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44 results on '"Krishna, Neethu"'

32. Do alternative approaches work in surgical septal myectomy?

Author

Varma, Praveen Kerala, Krishna, Neethu, Jose, Rajesh, Gopal, Kirun, and Ahamed, Hisham

Abstract

Trans-aortic septal myectomy is the gold standard for septal reduction therapy. This technique has low peri-procedural mortality and excellent long-term survival. Moreover, it relieves the heart failure symptoms and improves the quality of life. Secondary chordal cutting along with septal myectomy has shown to improve the outcome but can potentially cause deterioration of left ventricular function. In patients with relatively thin inter-ventricular septum, abnormalities of mitral valve apparatus may be the main reason for systolic anterior motion and left ventricular outflow tract obstruction. These patients may require additional procedures on the mitral valve to shift the coaptation plane away from outflow tract. Mitral valve replacement should be performed only in patients with intrinsic mitral valve abnormalities that are not suitable for repair and its routine use along with limited septal myectomy should be discouraged. Minimal access surgery although attractive in concept requires more robust data before universal application. [ABSTRACT FROM AUTHOR]

Published
2022
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40. Female Gender is not a Risk Factor for Early Mortality after Coronary Artery Bypass Grafting.

Author

Gurram, Akhil, Krishna, Neethu, Vasudevan, Anu, Baquero, Luis, Jayant, Aveek, Varma, Praveen, Baquero, Luis Alberto, and Varma, Praveen Kerala

Subjects
*CORONARY artery bypass, *KIDNEY failure, *DISEASE risk factors, *MEDIASTINITIS, *PATIENT readmissions, *GENDER, *LOGISTIC regression analysis
Abstract

Background: The female gender is considered as a risk factor for morbidity and mortality after coronary artery bypass grafting (CABG).Aim: In this analysis, we assessed the impact of female gender on early outcome after CABG.Study Design: This is a retrospective analysis of data from our center situated in South India.Statistical Analysis: Patients were categorized according to gender and potential differences in pre-operative and post-operative factors were explored. Significant risk factors were then built in a multivariate model to account for differences in predicting gender influence on surgical outcome.Methods: 773 consecutive patients underwent first time CABG between January 2015 and December 2016. 96.77% of cases were performed using off-pump technique. 132 (17.07%) patients were females. These patients formed the study group.Results: The in-house/ 30-day mortality in females was similar to that of males (3.03% vs. 3.12%, p value 0.957). Mediastinitis developed more commonly in females (5.35% vs. 1.30%; p value 0.004) compared to males. There were more re-admissions to hospital for female patients (21.37% in females vs. 10.14% in males, p value <0.001). In multivariate analysis using logistic regression; there was a significant association between age (OR 1.08), chronic obstructive airway disease (OR 4.315), and use of therapeutic antibiotics (OR 6.299), IABP usage (OR 11.18) and renal failure requiring dialysis (OR 28.939) with mortality.Conclusions: Early mortality in females was similar to that of males. Females were associated with higher rate of wound infection and readmission to hospital. [ABSTRACT FROM AUTHOR]

Published
2019
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