1. Merkel Cell Carcinoma, Version 1.2018, NCCN Clinical Practice Guidelines in Oncology
- Author
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Karin G. Hoffmann, Manisha J. Loss, Roy H. Decker, Rachel C. Blitzblau, Sumaira Z. Aasi, Murad Alam, Karthik Ghosh, Yaohui G. Xu, Roy C. Grekin, Valencia Thomas, Ashok R. Shaha, Anita M. Engh, James S. Andersen, Kishwer S. Nehal, Thomas Olencki, Carlo M. Contreras, Kenneth Grossman, Glen M. Bowen, Gregory A. Daniels, Kris Fisher, Alan L. Ho, Jane L. Messina, Paul Nghiem, John A. Zic, Igor Puzanov, Karl D. Lewis, Daniel D. Lydiatt, Brian R. Gastman, Jeffrey M. Farma, Chrysalyne D. Schmults, and Christopher K. Bichakjian
- Subjects
Oncology ,medicine.medical_specialty ,Skin Neoplasms ,medicine.medical_treatment ,Aftercare ,Merkel cell polyomavirus ,Medical Oncology ,Systemic therapy ,Article ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Carcinoma ,Humans ,Societies, Medical ,biology ,Merkel cell carcinoma ,business.industry ,Incidence ,food and beverages ,Chemoradiotherapy ,biology.organism_classification ,medicine.disease ,Primary tumor ,United States ,Carcinoma, Merkel Cell ,Clinical Practice ,Radiation therapy ,030220 oncology & carcinogenesis ,Biomarker (medicine) ,business - Abstract
This selection from the NCCN Guidelines for Merkel Cell Carcinoma (MCC) focuses on areas impacted by recently emerging data, including sections describing MCC risk factors, diagnosis, workup, follow-up, and management of advanced disease with radiation and systemic therapy. Included in these sections are discussion of the new recommendations for use of Merkel cell polyomavirus as a biomarker and new recommendations for use of checkpoint immunotherapies to treat metastatic or unresectable disease. The next update of the complete version of the NCCN Guidelines for MCC will include more detailed information about elements of pathology and addresses additional aspects of management of MCC, including surgical management of the primary tumor and draining nodal basin, radiation therapy as primary treatment, and management of recurrence.
- Published
- 2018