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3. Allergologische Diagnostik von Überempfindlichkeitsreaktionen auf Arzneimittel

Author

Brockow, K., primary, Wurpts, G., additional, Trautmann, A., additional, Pfützner, W., additional, Treudler, R., additional, Bircher, A.J., additional, Brehler, R., additional, Buhl, T., additional, Dickel, H., additional, Fuchs, T., additional, Jakob, T., additional, Kurz, J., additional, Kreft, B., additional, Lange, L., additional, Merk, H.F., additional, Mockenhaupt, M., additional, Mülleneisen, N., additional, Ott, H., additional, Ring, J., additional, Ruëff, F., additional, Sachs, B., additional, Sitter, H., additional, Wedi, B., additional, Wöhrl, S., additional, Worm, M., additional, and Zuberbier, T., additional

Published
2023
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7. Hodentumoren

Author

Kreft, B., Albers, P., Layer, Günter, editor, van Kaick, Gerhard, editor, and Delorme, Stefan, editor

Published
2008
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13. Infektiöse Panuveitis bei drogenabhängiger Patientin

Author

Burghardt, Marie, Viestenz, A., Kreft, B., and Wienrich, R.

Subjects
ddc: 610, Medicine and health
Abstract

Hintergrund: Die okulären Manifestationsformen einer Syphilis haben chamäleonartige Charakteristik und können von einer Bindehautreizung bis hin zur Panuveitis, sowie Neuroparalyse reichen. Nach Angaben des RKI wurde 2019 mit 7.889 ein Höchststand an Neuinfektionen erreicht, was [zum vollständigen Text gelangen Sie über die oben angegebene URL]

Published
2021
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24. Peanut���induced anaphylaxis in children and adolescents: Data from the European Anaphylaxis Registry

Author

Maris, Ioana, D��lle���Bierke, Sabine, Renaudin, Jean���Marie, Lange, Lars, Koehli, Alice, Spindler, Thomas, Hourihane, Jonathan, Scherer, Kathrin, Nemat, Katja, Kemen, C., Neust��dter, Irena, Vogelberg, Christian, Reese, Thomas, Yildiz, Ismail, Szepfalusi, Zsolt, Ott, Hagen, Straube, Helen, Papadopoulos, Nikolaos G., H��mmerling, Susanne, Staden, Ute, Polz, Michael, Mustakov, Tihomir, Cichocka���Jarosz, Ewa, Cocco, Renata, Fiocchi, Alessandro Giovanni, Fernandez���Rivas, Montserrat, Worm, Margitta, Gr��nhagen, J, Wittenberg, M, Beyer, K, Henschel, A, K��per, S, M��ser, A, Fuchs, T, Ru��ff, F, Wedi, B, Hansen, G, Buck, T, B��sselberg, J, Dr��gerdt, R, Pfeffer, L, Dickel, H, K��rner���Rettberg, C, Merk, H, Lehmann, S, Bauer, A, Nordwig, A, Zeil, S, Hannapp, C, Wagner, N, Rietschel, E, Hunzelmann, N, Huseynow, I, Treudler, R, Aurich, S, Prenzel, F, Klimek, L, Pfaar, O, Reider, N, Aberer, W, Varga, E, Bogatu, B, Schmid���Grendelmeier, P, Guggenheim, R, Riffelmann, F, Kreft, B, Kinaciyan, K, Hartl, L, Ebner, C, Horak, F, Brehler, R, Witte, J, Buss, M, Hompes, S, Bieber, T, Gernert, S, B��cheler, M, Rabe, U, Brosi, W, Nestoris, S, Hawranek, T, Lang, R, Bruns, R, Pf��hler, C, Eng, P, Schweitzer���Krantz, S, Meller, S, Rebmann, H, Fischer, J, Stichtenoth, G, Thies, S, Gerstlauer, M, Utz, P, Neust��dter, I, Klinge, J, Volkmuth, S, Plank���Habibi, S, Schilling, B, Kleinheinz, A, Br��ckner, A, Sch��kel, K, Manolaraki, I, Kowalski, M, Solarewicz���Madajek, K, Tscheiller, S, Seidenberg, J, Cardona, V, Garcia, B, Bilo, M, Caba��es Higuero, N, Vega Castro, A, Poziomkowska���G��sicka, I, B��sing, S, Virchow, C, Christoff, G, Jappe, U, M��ller, S, Kn��pfel, F, Correard, A���K, Rogala, B, Montoro, A, Brandes, A, Muraro, A, Zimmermann, N, Hernandez, D, Minale, P, Niederwimmer, J, Zahel, B, Dahdah, L, Arasi, S, Reissig, A, Eitelberger, F, Asero, R, Hermann, F, Zeidler, S, Pistauer, S, Gei��ler, M, Ensina, L, Plaza Martin, A, Meister, J, Stieglitz, S, Hamelmann, E, and Network For Online Registration Of Anaphylaxis (NORA)

Subjects
0301 basic medicine, Allergy, medicine.medical_specialty, Adolescent, Arachis, Epinephrine, Immunology, Peanut allergy, Peanut-induced anaphylaxis, paediatrics, 03 medical and health sciences, 0302 clinical medicine, Food allergy, Internal medicine, medicine, anaphylaxis, Humans, Immunology and Allergy, Peanut Hypersensitivity, In patient, Registries, Child, Asthma, food allergy, business.industry, food and beverages, medicine.disease, Comorbidity, 030104 developmental biology, 030228 respiratory system, business, Anaphylaxis, 600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
Abstract

Background Peanut allergy has a rising prevalence in high-income countries, affecting 0.5%-1.4% of children. This study aimed to better understand peanut anaphylaxis in comparison to anaphylaxis to other food triggers in European children and adolescents. Methods Data was sourced from the European Anaphylaxis Registry via an online questionnaire, after in-depth review of food-induced anaphylaxis cases in a tertiary paediatric allergy centre. Results 3514 cases of food anaphylaxis were reported between July 2007 - March 2018, 56% in patients younger than 18 years. Peanut anaphylaxis was recorded in 459 children and adolescents (85% of all peanut anaphylaxis cases). Previous reactions (42% vs. 38%; p = .001), asthma comorbidity (47% vs. 35%; p < .001), relevant cofactors (29% vs. 22%; p = .004) and biphasic reactions (10% vs. 4%; p = .001) were more commonly reported in peanut anaphylaxis. Most cases were labelled as severe anaphylaxis (Ring&Messmer grade III 65% vs. 56% and grade IV 1.1% vs. 0.9%; p = .001). Self-administration of intramuscular adrenaline was low (17% vs. 15%), professional adrenaline administration was higher in non-peanut food anaphylaxis (34% vs. 26%; p = .003). Hospitalization was higher for peanut anaphylaxis (67% vs. 54%; p = .004). Conclusions The European Anaphylaxis Registry data confirmed peanut as one of the major causes of severe, potentially life-threatening allergic reactions in European children, with some characteristic features e.g., presence of asthma comorbidity and increased rate of biphasic reactions. Usage of intramuscular adrenaline as first-line treatment is low and needs to be improved. The Registry, designed as the largest database on anaphylaxis, allows continuous assessment of this condition.

Published
2021
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25. Penicillin tolerance induction in pregnancy: Allergological statement on the recommendation of the current guideline on diagnosis and treatment of syphilis (AWMF register no. 059-002)

Author

Wedi, B., Aberer, W., Brockow, K., Dickel, H., Brehler, R., Jakob, T., Kreft, B., Mahler, V, Merk, H. F., Muelleneisen, N., Ott, H., Pfuetzner, W., Roeseler, S., Rueff, F., Sunderkoetter, C., Trautmann, A., Treudler, R., Worm, M., Wurpts, G., Wedi, B., Aberer, W., Brockow, K., Dickel, H., Brehler, R., Jakob, T., Kreft, B., Mahler, V, Merk, H. F., Muelleneisen, N., Ott, H., Pfuetzner, W., Roeseler, S., Rueff, F., Sunderkoetter, C., Trautmann, A., Treudler, R., Worm, M., and Wurpts, G.

Published
2021

29. Penicillin-Toleranzinduktion in der Schwangerschaft: Allergologische Stellungnahme zur Empfehlung der aktuellen Leitlinie Diagnostik und Therapie der Syphilis (AWMF-Register-Nr. 059-002)

Author

Wedi, B., primary, Aberer, W., additional, Brockow, K., additional, Dickel, H., additional, Brehler, R., additional, Jakob, T., additional, Kreft, B., additional, Mahler, V., additional, Merk, H.F., additional, Mülleneisen, N., additional, Ott, H., additional, Pfützner, W., additional, Röseler, S., additional, Ruëff, F., additional, Sunderkötter, C., additional, Trautmann, A., additional, Treudler, R., additional, Worm, M., additional, and Wurpts, G., additional

Published
2021
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43. Food-induced anaphylaxis and cofactors – data from the anaphylaxis registry

Author

Worm, M., Scherer, K., Köhli-Wiesner, A., Ruëff, F., Mahler, V., Lange, L., Treudler, R., Rietschel, E., Szepfalusi, Z., Lang, R., Rabe, U., Reese, T., Schwerk, N., Beyer, K., Hompes, S., Bircher, A., Przybilla, B., Hawranek, T., Hansen, G., Friedrichs, F., Merk, H., Tenbrock, K., Lehmann, S., Gerstlauer, M., Kleine-Tebbe, J., Niggemann, B., Dickel, H., Bücheler, M., Bieber, T., Hanfland, J., Schmitt-Grohe, S., Vlajnic, D., Heckmann, V., Nemat, K., Schäkel, K., Nordwig, A., Schuster, A., Schweitzer-Krantz, S., Hillen, U., Kopp, M., Szliska, C., Klinge, J., Neustädter, I., Fuchs, T., Bruns, R., Marsch, C., Kreft, B., Coors, E., Rebien, W., Wedi, B., Pföhler, C., Rett, M., Henzgen, M., Vöhringer, P., Fölster-Holst, R., Hunzelmann, N., Siebenhaar, G., Nestoris, S., Schirpke, C., Grabbe, J., Stichtenoth, G., Ring, J., Brockow, K., Brehler, R., Yildiz, I., Volkmuth, S., Geißler, M., Polz, M., Riffelmann, F., Thies, S., Lepp, U., Rebmann, H., Spindler, T., Klimek, L., Pfaar, O., Brosi, W., Aberer, W., Varga, E., Reider, N., Huttegger, I., Kinaciyan, T., Hoffmann-Sommergruber, K., Eng, P., Helbling, A., Eigenmann, P., Guggenheim, R., and Schmid-Grendelmeier, P.

Subjects
medicine.medical_specialty, Pediatrics, Allergy, Food induced anaphylaxis, Physical activity, registry, food allergens, 03 medical and health sciences, 0302 clinical medicine, 030225 pediatrics, Internal medicine, anaphylaxis, cofactors, medicine, Insect venom, Food allergens, General Environmental Science, 2. Zero hunger, business.industry, General Engineering, Allergic asthma, Atopic dermatitis, medicine.disease, 3. Good health, 030228 respiratory system, Concomitant, General Earth and Planetary Sciences, business, Anaphylaxis, Research Article
Abstract

Food allergens are frequent causes of anaphylaxis. In particular in children and adolescents they are the most frequent elicitors of severe allergic reactions, and in adults food allergens rank third behind insect venom and drugs. Since July 2006 severe allergic reactions from Germany, Austria, and Switzerland are collected in the anaphylaxis registry. Currently 78 hospitals and private practises are connected. From July 2006 until February 2009 1,156 severe allergic reactions were registered. Among children and adolescents (n = 187, age range from 3 months to 17 years) food allergens were the most frequent triggers, comprising 58% of cases. In the adult group (n = 968, 18 - 85 years) food allergens were in the third position (16.3%) behind insect venom and drugs. In children legumes (31%) and in particular peanuts were frequently responsible food allergens, followed by tree nuts (25%) with hazelnut being the most frequent elicitor. In adults fruits (13.4%) most often induced severe food-dependent anaphylaxis, but also animal products (12.2%); among these most frequently crustaceans and molluscs. Cofactors were often suspected in food-dependent anaphylaxis, namely in 39% of the adult group and in 14% of the pediatric group. In adults drugs (22%) and physical activity (10%) were reported to be the most frequent cofactors, in children physical activity was suspected in 8.7% and drugs in 2.6%. Concomitant diseases like atopic dermatitis, allergic asthma, or allergic rhinoconjunctivitis were reported in 78% of children and adolescents and in 67% of the adults. In conclusion, food-induced anaphylaxis, its cofactors and concomitant diseases are age-dependent. The data offers to identify risk factors of anaphylaxis.

Published
2017

46. Erratum: Contact sensitization to plants of the Compositae family: Data of the Information Network of Departments of Dermatology (IVDK) from 2007 to 2016 (vol 80, pg 222, 2019)

Author

Baron, J. M., Grabbe, J., Ludwig, A., Bircher, A., Laubstein, B., Zuberbier, T., Worm, M., Simon, D., Effendy, Isaak, Dickel, H., Fartasch, M., Meyersburg, D., Patsinakidis, N., Zutt, M., Große-Hüttmann, P., Hausenblas, P., Martin, V., Reich, K., Breuer, K., Vieluf, D., Jung, A., Lippert, U., Pilz, B., Frosch, P. J., Mydlach, B., Pirker, C., Herbst, R., Kügler, K., Beiteke, U., Richter, G., Aschoff, R., Spornraft-Ragaller, P., Bauer, A., Koch, A., Peters, K. -P., Diepgen, T. L., Hertl, M., Mahler, V., Wagner, N., Ockenfels, H. -M., Hillen, U., Schwantes, H., Szliska, Ch., Geier, J., Meyer, J., Grunwald-Delitz, H., Kaatz, M., Kränke, B., Aberer, W., Jünger, M., Fuchs, Th., Buhl, T., Gaber, G., Lübbe, D., Kreft, B., Kiehn, M., Wessbecher, R., Coors, E., Witte, J., Seemann, U., Schröder-Kraft, C., Schaefer, T., Werfel, Th., Kapp, A., Schulze-Dirks, A., Hartmann, M., Jappe, U., Schäkel, K., Weisshaar, E., Löffler, H., Bahmer, F. A., Koch, P., Pföhler, C., Gebhardt, M., Wigger-Alberti, W., Schliemann, S., Brasch, J., Spring, P., Curdin, C., Treudler, R., Nestoris, St., Shimanovich, I., Hartmann, K., Recke, A., Becker, D., Bayerl, Ch., Kurzen, H., Booken, D., Klemke, C. -D., Ludwig-Peitsch, W., Schmieder, A., Pfützner, W., Hoffmann, J., Stadler, R., Oppel, T., Przybilla, B., Thomas, P., Schuh, T., Eben, R., Molin, S., Agathos, M., Ramrath, K., Georgi, M., Isbary, G., Rakoski, J., Darsow, U., Biedermann, T., Hellweg, B., Brehler, R., Behring, M., Müller, I., Debus, D., Bachtler, A., Ertner, K., Baur, V., Padeken, M., Kautz, O., Uter, W., John, S. M., Schwanitz, H. J., Schürer, N., Skudlik, Ch., Prager, W., Heise, H., Trcka, J., Rothaupt, D., Plaza, T., Nist, G., Rieker-Schwienbacher, J., Lischka, G., Roecken, M., Fischer, J., Staib, G., Hinrichs, R., Weiss, J., Arnold, J., Trautmann, A., Knopf, B., Teubner, D., Mechtel, D., Ballmer-Weber, B., and Navarini, A.

Published
2019

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