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A synthesis laboratory has been established for the preparation of compounds to be evaluated against viruses of interest to U. S. Army Medical Research Institute of Infectious Diseases. The synthesis of known compounds as well as new compounds has been undertaken, and all compounds are being made in sufficient quantity to allow for full evaluation. The compounds prepared under this contract included nucleoside analogs and other heterocyclic compounds including 6-azauridine analogs, ribavirin analogs, and 1-substituted 4-acetyl-4-phenylpiperidines. Antiviral; synthesis laboratory; nucleoside analogs; heterocyclic compounds; 6-azauridine analogs; ribavirin analogs; 1-substituted 4-acetyl-4-phenylpiperidines.

A synthesis laboratory has been established for the preparation of compounds to be evaluated against viruses of interest of U.S. Army Medical Research Institute of Infectious Diseases. The synthesis of known compounds as well as new compounds has been undertaken, and all compounds are being made in sufficient quantity to allow for full evaluation. Among the compounds prepared thus far are 1-benzyloxy-adenosines, 9-substituted 1-benzyloxyadenines, 1,2,4,5,3,6,-tetraazadiphosphorines, substituted imidazoles, selenadiazoles, triazoles, triazolotriazoles, guanidines, pyrazoles, adamantane derivatives, chloroquines, Ni-aminonucleosides, allopurinol acyclonucleosides, nucleotides of ribavirin and tiazofurin, and various other heterocyclic compounds.

A synthesis laboratory has been established for the preparation of compounds to be evaluated against viruses of interest to U.S. Army Medical Research Institute of Infectious Diseases. The synthesis of known compounds as well as new compounds has been undertaken, and all compounds are being made in sufficient quantity to allow for full evaluation. Among the compounds prepared thus far are 1-benzyl-benyloxadenines, 1,2,4,5,3,6- tetraazadiphosphorines, substituted imidazoles, selenadiazoles, triazoles, oxyadenosines, 9-substituted 1-benzyltriazoles, triazolotriazoles, guanidines, pyrazoles, adamantane derivatives, chloroquines, N1-aminonucleosides, allopurinol acyclonucleosides, nucleotides of ribavirin and tiazofurin, and various other heterocyclic compounds. Keywords: Antiviral agents. (kt)

48 p., Making of America (MOA), (dlps) AHL6962.0001.001, (lccallno) HV 37 .K9, http://quod.lib.umich.edu/t/text/accesspolicy.html

xvii, 810 p. 23cm., First edition, 1871., "The Lutheran reformation in those features which distinguish it from the Zwinglian and Calvinistic reformations ... forms the topic of the book."--Pref., Bibliographical foot-notes., Making of America (MOA), (dlps) AJK2557.0001.001, (lccallno) BX 8069 .K91, http://quod.lib.umich.edu/t/text/accesspolicy.html

xxii, [2], 1044 p. ; 21cm., (dlps) AJE2953.0001.001, http://name.umdl.umich.edu/AJE2953.0001.001, http://quod.lib.umich.edu/t/text/accesspolicy.html

48 p., Making of America (MOA), (dlps) AHL6962.0001.001, (lccallno) HV 37 .K9, http://quod.lib.umich.edu/t/text/accesspolicy.html

xvii, 810 p. 23cm., First edition, 1871., "The Lutheran reformation in those features which distinguish it from the Zwinglian and Calvinistic reformations ... forms the topic of the book."--Pref., Bibliographical foot-notes., Making of America (MOA), (dlps) AJK2557.0001.001, (lccallno) BX 8069 .K91, http://quod.lib.umich.edu/t/text/accesspolicy.html

xxii, [2], 1044 p. ; 21cm., (dlps) AJE2953.0001.001, http://name.umdl.umich.edu/AJE2953.0001.001, http://quod.lib.umich.edu/t/text/accesspolicy.html

A synthesis laboratory has been established for the preparation of compounds to be evaluated against viruses of interest to U.S. Army Medical Research Institute of Infectious Diseases. The synthesis of known compounds as well as new compounds has been undertaken, and all compounds are being made in sufficient quantity to allow for full evaluation. Types of compounds prepared thus far include: 1-benzyloxyadenosines, 9-substituted 1-benzyloxyadenines, 1,2, 4,5,3,6-tetraazadiphosphorines, substituted imidazoles, selenadiazoles triazoles, triazolotriazoles, guanidines, pyrazoles, adamantanecarboxamides, adamantylthioureas, adamantylthiosemicarbazides, and chloroquines.

A synthesis laboratory has been established for the preparation of compounds to be evaluated against viruses of interest to U.S. Army medical Research Institute of Infectious Diseases. The synthesis of known compounds as well as new compounds has been under taken, and all compounds are being made in sufficient quantity to allow for full evaluation. Among the compounds prepared thus far are 1-benzyloxyadenosines, 9-substituted 1-benzyloxyadenines, 1,2,4,5,3,6-tetraazadiphosphorines, substituted imidazoles, selanadiazoles, triazoles, triazolotriazoles, guanidines, pyrazoles, adamantane derivatives, chloroquines, N-aminonucleosides, allopurinol acyclonuclosides, nucleotides of ribavirin and tiazofurin, and various other heterocyclic compounds. Keywords: Antiviral agents; Synthesis (Chemistry); Organic chemistry. (kt)

A synthesis laboratory has been established for the preparation of compounds to be evaluated against viruses of interest to U.S. Army Medical Research Institute of Infectious Diseases. The synthesis of known compounds as well as new compounds has been undertaken, and all compounds are being made in sufficient quantity to allow for full evaluations. Types of compounds prepared thus far include 1-benzyloxyadenosines, amidines, 1,2,4,5,3,6-tetraazadiphosphorines, substituted imidazoles, and several compounds derived from ascorbic acid. Keywords: antiviral agents.