27 results on '"Kral, Astrid M."'
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2. Supplementary Methods, Figures 1 - 3, Tables 1 - 3 from Molecular and Biologic Analysis of Histone Deacetylase Inhibitors with Diverse Specificities
3. Characterization of recombinant human farnesyl-protein transferase: cloning, expression, farnesyl diphosphate binding, and functional homology with yeast prenyl-protein transferases
4. [I] Bacterial expression and purification of human protein prenyltransferases using epitope-tagged, translationally coupled systems
5. Divergent Kinetics Differentiate the Mechanism of Action of Two HDAC Inhibitors
6. Delayed and Prolonged Histone Hyperacetylation with a Selective HDAC1/HDAC2 Inhibitor
7. Molecular and Biologic Analysis of Histone Deacetylase Inhibitors with Diverse Specificities
8. Exploring the pharmacokinetic properties of phosphorus-containing selective HDAC 1 and 2 inhibitors (SHI-1:2)
9. Parallel medicinal chemistry approaches to selective HDAC1/HDAC2 inhibitor (SHI-1:2) optimization
10. SAR profiles of spirocyclic nicotinamide derived selective HDAC1/HDAC2 inhibitors (SHI-1:2)
11. Optimization of biaryl Selective HDAC1&2 Inhibitors (SHI-1:2)
12. Phenylglycine and phenylalanine derivatives as potent and selective HDAC 1inhibitors (SHI-1)
13. Optimization of 2,3,5-trisubstituted pyridine derivatives as potent allosteric Akt1 and Akt2 inhibitors
14. Rapid assembly of diverse and potent allosteric Akt inhibitors
15. Development of Pyridopyrimidines as Potent Akt1/2 Inhibitors
16. Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)
17. Amino acid derivatives as histone deacetylase inhibitors
18. Design of novel histone deacetylase inhibitors
19. The discovery of 6-amino nicotinamides as potent and selective histone deacetylase inhibitors
20. Quantitative Analysis of Histone Deacetylase-1 Selective Histone Modifications by Differential Mass Spectrometry
21. Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1)
22. Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors
23. Identification of Tcf4 Residues Involved in High-Affinity β-Catenin Binding
24. Mutational Analysis of Conserved Residues of the ॆ-Subunit of Human Farnesyl:Protein Transferase
25. 2-Substituted Piperazines as Constrained Amino Acids. Application to the Synthesis of Potent, Non Carboxylic Acid Inhibitors of Farnesyltransferase
26. Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice
27. Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in rastransgenic mice
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