Search

Your search keyword '"Kozak, Osman"' showing total 33 results
Start Over Author "Kozak, Osman"
33 results on '"Kozak, Osman"'

1. Endovascular thrombectomy plus medical care versus medical care alone for large ischaemic stroke: 1-year outcomes of the SELECT2 trial

Author

Sarraj, Amrou, Abraham, Michael G, Hassan, Ameer E, Blackburn, Spiros, Kasner, Scott E, Ortega-Gutierrez, Santiago, Hussain, Muhammad Shazam, Chen, Michael, Johns, Hannah, Churilov, Leonid, Pujara, Deep K, Shaker, Faris, Maali, Laith, Cardona Portela, Pere, Herial, Nabeel A, Gibson, Daniel, Kozak, Osman, Arenillas, Juan F, Yan, Bernard, Pérez de la Ossa, Natalia, Sundararajan, Sophia, Hu, Yin C, Cordato, Dennis J, Manning, Nathan W, Hanel, Ricardo A, Aghaebrahim, Amin N, Budzik, Ronald F, Hicks, William J, Blasco, Jordi, Wu, Teddy Y, Tsai, Jenny P, Schaafsma, Joanna D, Gandhi, Chirag D, Al-Mufti, Fawaz, Sangha, Navdeep, Warach, Steven, Kleinig, Timothy J, Yogendrakumar, Vignan, Ng, Felix, Samaniego, Edgar A, Abdulrazzak, Mohammad A, Parsons, Mark W, Rahbar, Mohammad H, Nguyen, Thanh N, Fifi, Johanna T, Mendes Pereira, Vitor, Lansberg, Maarten G, Albers, Greg W, Furlan, Anthony J, Jabbour, Pascal, Sitton, Clark W, Sila, Cathy, Bambakidis, Nicholas, Davis, Stephen M, Wechsler, Lawrence, Hill, Michael D, Grotta, James C, Ribo, Marc, and Campbell, Bruce C V

Published
2024
Full Text
View/download PDF

2. Anticoagulation Use and Endovascular Thrombectomy in Patients with Large Core Stroke: A Secondary Analysis of the SELECT2 Trial.

Author

Pujara, Deep K., Hussain, M. Shazam, Abraham, Michael G., Ortega‐Gutierrez, Santiago, Chen, Michael, Kasner, Scott E., Churilov, Leonid, Sitton, Clark W., Blackburn, Spiros, Sundararajan, Sophia, Hu, Yin C., Herial, Nabeel A., Budzik, Ronald F., Hicks, William J., Arenillas, Juan F., Tsai, Jenny P., Kozak, Osman, Cordato, Dennis J., Manning, Nathan W., and Hanel, Ricardo A.

Subjects
INTRACRANIAL hemorrhage, ENDOVASCULAR surgery, ANTICOAGULANTS, CONGESTIVE heart failure, ORAL medication
Abstract

Endovascular thrombectomy (EVT) safety and efficacy in patients with large core infarcts receiving oral anticoagulants (OAC) are unknown. In the SELECT2 trial (NCT03876457), 29 of 180 (16%; vitamin K antagonists 15, direct OACs 14) EVT, and 18 of 172 (10%; vitamin K antagonists 3, direct OACs 15) medical management (MM) patients reported OAC use at baseline. EVT was not associated with better clinical outcomes in the OAC group (EVT 6 [4–6] vs MM 5 [4–6], adjusted generalized odds ratio 0.89 [0.53–1.50]), but demonstrated significantly better outcomes in patients without OAC (EVT 4 [3–6] vs MM 5 [4–6], adjusted generalized odds ratio 1.87 [1.45–2.40], p = 0.02). The OAC group had higher comorbidities, including atrial fibrillation (70% vs 17%), congestive heart failure (28% vs 10%), and hypertension (87% vs 72%), suggesting increased frailty. However, the results were consistent after adjustment for these comorbidities, and was similar regardless of the type of OACs used. Whereas any hemorrhage rates were higher in the OAC group receiving EVT (86% in OAC vs 70% in no OAC), no parenchymal hemorrhage or symptomatic intracranial hemorrhage were observed with OAC use in both the EVT and MM arms. Although we did not find evidence that the effect was due to excess hemorrhage or confounded by underlying cardiac disease or older age, OAC use alone should not exclude patients from receiving EVT. Baseline comorbidities and ischemic injury extent should be considered while making individualized treatment decisions. ANN NEUROL 2024;96:887–894 [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

4. Clinical relevance of intracranial hemorrhage after thrombectomy versus medical management for large core infarct: a secondary analysis of the SELECT2 randomized trial

Author

Chen, Michael, primary, Joshi, Krishna C, additional, Kolb, Bradley, additional, Sitton, Clark W, additional, Pujara, Deep Kiritbhai, additional, Abraham, Michael G, additional, Ortega-Gutierrez, Santiago, additional, Kasner, Scott E, additional, Hussain, Shazam M, additional, Churilov, Leonid, additional, Blackburn, Spiros, additional, Sundararajan, Sophia, additional, Hu, Yin C, additional, Herial, Nabeel, additional, Arenillas, Juan F, additional, Tsai, Jenny P, additional, Budzik, Ronald F, additional, Hicks, William, additional, Kozak, Osman, additional, Yan, Bernard, additional, Cordato, Dennis, additional, Manning, Nathan W, additional, Parsons, Mark, additional, Hanel, Ricardo A, additional, Aghaebrahim, Amin, additional, Wu, Teddy, additional, Cardona Portela, Pere, additional, Gandhi, Chirag D, additional, Al-Mufti, Fawaz, additional, Perez de la Ossa, Natalia, additional, Schaafsma, Joanna, additional, Blasco, Jordi, additional, Sangha, Navdeep, additional, Warach, Steven, additional, Kleinig, Timothy J, additional, Johns, Hannah, additional, Shaker, Faris, additional, Abdulrazzak, Mohammad A, additional, Ray, Abhishek, additional, Sunshine, Jeffery, additional, Opaskar, Amanda, additional, Duncan, Kelsey R, additional, Xiong, Wei, additional, Al-Shaibi, Faisal K, additional, Samaniego, Edgar A, additional, Nguyen, Thanh N, additional, Fifi, Johanna T, additional, Tjoumakaris, Stavropoula I, additional, Jabbour, Pascal, additional, Mendes Pereira, Vitor, additional, Lansberg, Maarten G, additional, Sila, Cathy, additional, Bambakidis, Nicholas C, additional, Davis, Stephen, additional, Wechsler, Lawrence, additional, Albers, Gregory W, additional, Grotta, James C, additional, Ribo, Marc, additional, Hassan, Ameer E, additional, Campbell, Bruce, additional, Hill, Michael D, additional, and Sarraj, Amrou, additional

Published
2024
Full Text
View/download PDF

5. Endovascular Thrombectomy Treatment Effect in Direct vs Transferred Patients With Large Ischemic Strokes: A Prespecified Analysis of the SELECT2 Trial.

Author

Sarraj, Amrou, Hill, Michael D., Hussain, M. Shazam, Abraham, Michael G., Ortega-Gutierrez, Santiago, Chen, Michael, Kasner, Scott E., Churilov, Leonid, Pujara, Deep K., Johns, Hannah, Blackburn, Spiros, Sundararajan, Sophia, Hu, Yin C., Herial, Nabeel A., Budzik, Ronald F., Hicks, William J., Arenillas, Juan F., Tsai, Jenny P., Kozak, Osman, and Cordato, Dennis J.

Published
2024
Full Text
View/download PDF

6. Trial of Endovascular Thrombectomy for Large Ischemic Strokes

Author

Sarraj, Amrou, primary, Hassan, Ameer E., additional, Abraham, Michael G., additional, Ortega-Gutierrez, Santiago, additional, Kasner, Scott E., additional, Hussain, M. Shazam, additional, Chen, Michael, additional, Blackburn, Spiros, additional, Sitton, Clark W., additional, Churilov, Leonid, additional, Sundararajan, Sophia, additional, Hu, Yin C., additional, Herial, Nabeel A., additional, Jabbour, Pascal, additional, Gibson, Daniel, additional, Wallace, Adam N., additional, Arenillas, Juan F., additional, Tsai, Jenny P., additional, Budzik, Ronald F., additional, Hicks, William J., additional, Kozak, Osman, additional, Yan, Bernard, additional, Cordato, Dennis J., additional, Manning, Nathan W., additional, Parsons, Mark W., additional, Hanel, Ricardo A., additional, Aghaebrahim, Amin N., additional, Wu, Teddy Y., additional, Cardona-Portela, Pere, additional, Pérez de la Ossa, Natalia, additional, Schaafsma, Joanna D., additional, Blasco, Jordi, additional, Sangha, Navdeep, additional, Warach, Steven, additional, Gandhi, Chirag D., additional, Kleinig, Timothy J., additional, Sahlein, Daniel, additional, Elijovich, Lucas, additional, Tekle, Wondwossen, additional, Samaniego, Edgar A., additional, Maali, Laith, additional, Abdulrazzak, M. Ammar, additional, Psychogios, Marios N., additional, Shuaib, Ashfaq, additional, Pujara, Deep K., additional, Shaker, Faris, additional, Johns, Hannah, additional, Sharma, Gagan, additional, Yogendrakumar, Vignan, additional, Ng, Felix C., additional, Rahbar, Mohammad H., additional, Cai, Chunyan, additional, Lavori, Philip, additional, Hamilton, Scott, additional, Nguyen, Thanh, additional, Fifi, Johanna T., additional, Davis, Stephen, additional, Wechsler, Lawrence, additional, Pereira, Vitor M., additional, Lansberg, Maarten G., additional, Hill, Michael D., additional, Grotta, James C., additional, Ribo, Marc, additional, Campbell, Bruce C., additional, and Albers, Gregory W., additional

Published
2023
Full Text
View/download PDF

7. Onyx Versus Particles for Middle Meningeal Artery Embolization in Chronic Subdural Hematoma

Author

Shehabeldin, Mohamed, primary, Amllay, Abdelaziz, additional, Jabre, Roland, additional, Chen, Ching-Jen, additional, Schunemann, Victoria, additional, Herial, Nabeel A., additional, Gooch, M. Reid, additional, Mackenzie, Larami, additional, Choe, Hana, additional, Tjoumakaris, Stavropoula, additional, Rosenwasser, Robert H., additional, Jabbour, Pascal, additional, and Kozak, Osman, additional

Published
2022
Full Text
View/download PDF

10. Early Multicenter Experience With the Neuroform Atlas Stent: Feasibility, Safety, and Efficacy

Author

Sweid, Ahmad, primary, Herial, Nabeel, additional, Sajja, Kalyan, additional, Chalouhi, Nohra, additional, Velagapudi, Lohit, additional, Doermann, Allison, additional, Kardon, Adam, additional, Tjoumakaris, Stavropoula, additional, Zarzour, Hekmat, additional, Smith, Michelle J, additional, Choe, Hana, additional, Shah, Qaisar, additional, Mackenzie, Larami, additional, Kozak, Osman, additional, Rosenwasser, Robert H, additional, Jabbour, Pascal, additional, and Gooch, M Reid, additional

Published
2021
Full Text
View/download PDF

12. SELECTion criteria for large core trials: dogma or data?

Author

Sarraj, Amrou Campbell, Bruce Ribo, Marc Hussain, Muhammad Shazam Chen, Michael Abraham, Michael G. Lansberg, Maarten G. Mendes Pereira, Vitor Blackburn, Spiros Sitton, Clark W. and Budzik, Ronald F. Perez de la Ossa, Natalia Arenillas, Juan F. Wu, Teddy Blasco, Jordi Mullen, Michael Schaafsma, Joanna Tsai, Jenny P. Sangha, Navdeep Kozak, Osman and Gibson, Daniel Warach, Steven Cordato, Dennis Manning, Nathan W. Kleinig, Timothy J. Olivot, Jean-Marc Elijovich, Lucas Tsivgoulis, Georgios Alexandrov, Andrei Jabbour, Pascal Yan, Bernard Kasner, Scott E. Arthur, Adam S. and Parsons, Mark Grotta, James C. Hassan, Ameer E. Albers, Gregory W. SELECT2 Investigators SELECT2 Steering Comm

Published
2021

13. Posterior reversible encephalopathy syndrome: associated clinical and radiologic findings

Author

Fugate, Jennifer E., Claassen, Daniel O., Cloft, Harry J., Kallmes, David F., Kozak, Osman S., and Rabinstein, Alejandro A.

Subjects
Encephalopathy -- Diagnosis, Encephalopathy -- Risk factors, Radiology -- Methods, Radiology, Medical -- Methods, Clinical medicine -- Research
Abstract

OBJECTIVE: To identify and define clinical associations and radiologic findings of posterior reversible encephalopathy syndrome (PRES). PATIENTS AND METHODS: Patients prospectively diagnosed as having PRES from October 1, 2005, through [...]

Published
2010

15. SELECTion criteria for large core trials: dogma or data?

Author

Sarraj, Amrou, primary, Campbell, Bruce, additional, Ribo, Marc, additional, Hussain, Muhammad Shazam, additional, Chen, Michael, additional, Abraham, Michael G, additional, Lansberg, Maarten G, additional, Mendes Pereira, Vitor, additional, Blackburn, Spiros, additional, Sitton, Clark W, additional, Budzik, Ronald F, additional, Pérez de la Ossa, Natalia, additional, Arenillas, Juan F, additional, Wu, Teddy, additional, Blasco, Jordi, additional, Mullen, Michael, additional, Schaafsma, Joanna, additional, Tsai, Jenny P, additional, Sangha, Navdeep, additional, Kozak, Osman, additional, Gibson, Daniel, additional, Warach, Steven, additional, Cordato, Dennis, additional, Manning, Nathan W, additional, Kleinig, Timothy J, additional, Olivot, Jean-Marc, additional, Elijovich, Lucas, additional, Tsivgoulis, Georgios, additional, Alexandrov, Andrei, additional, Jabbour, Pascal, additional, Yan, Bernard, additional, Kasner, Scott E, additional, Arthur, Adam S, additional, Parsons, Mark, additional, Grotta, James C, additional, Hassan, Ameer E, additional, and Albers, Gregory W, additional

Published
2021
Full Text
View/download PDF

17. Contributors

Author

Anderson, Robert J., primary, Balk, Robert A., additional, Barie, Philip S., additional, Barletta, Jeffrey F., additional, Barton, Richard G., additional, Bartter, Thaddeus, additional, Bashour, C. Allen, additional, Beale, Richard, additional, Bekes, Carolyn, additional, Bion, Julian, additional, Bleck, Thomas P., additional, Borunda, Delia, additional, Braithwaite, Susan S., additional, Browne, William T., additional, Buckley, John D., additional, Caironi, Pietro, additional, Carlesso, Eleonora, additional, Caronna, John J., additional, Chansky, Michael, additional, Chaptini, Louis, additional, Cilley, Jonathan H., additional, Cinel, Ismail, additional, Crnich, Christopher J., additional, Curti, Brendan D., additional, Danis, Marion, additional, Dellinger, R. Phillip, additional, Devlin, John W., additional, Dinh, Jack T., additional, Domínguez-Cherit, Guillermo, additional, Dries, David J., additional, Elfant, Adam B., additional, Ely, E. Wesley, additional, Emanuel, Ezekiel, additional, Faridi, Ahmad Bilal, additional, Farmer, J. Christopher, additional, Fraimow, Henry S., additional, Friedman, Yaakov, additional, Garwood, Susan, additional, Gattinoni, Luciano, additional, Gautam, Nandan, additional, Gessman, Lawrence J., additional, Ginsberg, Fredric, additional, Godke, John, additional, Goldman, H. Warren, additional, Groeneveld, A.B.J., additional, Gross, Robin, additional, Gurka, David P., additional, Haddad, Ghada, additional, Haupt, Marilyn T., additional, Hockstein, Michael J., additional, Hollenberg, Steven M., additional, Hudson, Leonard D., additional, Hunninghake, Gary W., additional, Jackson, James, additional, Jamison, C.A., additional, Jean, Smith, additional, Jneid, Hani, additional, Johnson, Robert G., additional, Jubran, Amal, additional, Kanagasundaram, Nigel S., additional, Karam, George, additional, Karam, Joseph A., additional, Karnik, Ankur A., additional, Karnik, Ashok M., additional, Kincaid, M. Sean, additional, Kozak, Osman Samil, additional, Kumar, Anand, additional, Lachant, Neil A., additional, Laghi, Franco, additional, Lapinsky, Stephen E., additional, Lavery, G.G., additional, Longo, Dan L., additional, Lotano, Ramya, additional, Lotano, Vincent E., additional, Luce, John M., additional, Luce, Judith A., additional, Maki, Dennis G., additional, March, Robert J., additional, Maree, Andrew O., additional, Marini, John, additional, Marshall, John C., additional, Masur, Henry, additional, McFadden, Christopher, additional, Metnitz, Philipp G.H., additional, Mirsen, Thomas R., additional, Moreno, Rui P., additional, Murphy, Nick, additional, Murray, Michael J., additional, Nagueh, Sherif F., additional, Niederman, Michael S., additional, Ostrosky-Zeichner, Luis, additional, Ouellette, Daniel R., additional, Ougorets, Igor, additional, Oyen, Lance J., additional, Paganini, Emil P., additional, Palacios, Igor F., additional, Pandharipande, Pratik, additional, Parrillo, Joseph E., additional, Patel, Amish, additional, Peikin, Steven, additional, Peruzzi, William, additional, Peters, Priscilla J., additional, Popovich, John, additional, Posadas-Calleja, Juan Gabriel, additional, Pratter, Melvin R., additional, Rajaram, S. Sujanthy, additional, Reay, Hannah, additional, Reboli, Annette C., additional, Rex, John H., additional, Rhodes, Andrew, additional, Rubin, Lewis J., additional, Rudis, Maria, additional, Safdar, Nasia, additional, Saffle, Jeffrey R., additional, Sahn, Steven A., additional, Schmidt, Gregory A., additional, Sharar, Sam R., additional, Silverman, Henry, additional, Sobek, Sabine, additional, Strange, Charlie, additional, Subramanian, Sanjay, additional, Tang, Wanchun, additional, Taylor, Robert W., additional, Teo, Boon Wee, additional, Tobin, Martin J., additional, Townsend, Sean, additional, Trohman, Richard, additional, Trzeciak, Stephen, additional, Turi, Zoltan G., additional, Turtz, Alan R., additional, Vincent, Jean-Louis, additional, Weil, Max Harry, additional, Weisberg, Lawrence S., additional, Werns, Steven, additional, Wijdicks, Eelco F.M., additional, Zanotti-Cavazzoni, Sergio L., additional, and Zimmerman, Janice L., additional

Published
2008
Full Text
View/download PDF

18. Posterior Circulation Tandem Occlusions

Author

Weinberg, Joshua, primary, Sweid, Ahmad, additional, Sajja, Kalyan, additional, Abbas, Rawad, additional, Asada, Ashlee, additional, Kozak, Osman, additional, Mackenzie, Larami, additional, Choe, Hana, additional, Gooch, M. Reid, additional, Herial, Nabeel, additional, Tjoumakaris, Stavropoula I, additional, Zarzour, Hekmat, additional, Rosenwasser, Robert H, additional, and Jabbour, Pascal, additional

Published
2020
Full Text
View/download PDF

19. Changes in Neuroendovascular Procedural Volume During the COVID‐19 Pandemic: An International Multicenter Study

Author

Qureshi, Adnan I., primary, Agunbiade, Samiat, additional, Huang, Wei, additional, Akhtar, Iqra N., additional, Abraham, Michael G., additional, Akhtar, Naveed, additional, Al‐Mufti, Fawaz, additional, Aytac, Emrah, additional, Balgetir, Ferhat, additional, Grigoryan, Mikayel, additional, Gomez, Camilo R., additional, Hassan, Ameer E., additional, Jani, Vishal, additional, Janjua, Nazli A., additional, Jiao, Liqun, additional, Khatri, Rakesh, additional, Kirmani, Jawad F., additional, Kobayashi, Adam, additional, Kozak, Osman, additional, Lee, Jun, additional, Lobanova, Iryna, additional, Mansour, Ossama Yassin, additional, Maud, Alberto, additional, Mazighi, Mikael, additional, Piotin, Michel, additional, Rodriguez, Gustavo J., additional, Siddiq, Farhan, additional, Suri, M. Fareed K., additional, and Tekle, Wondwossen G., additional

Published
2020
Full Text
View/download PDF

20. Early Multicenter Experience With the Neuroform Atlas Stent: Feasibility, Safety, and Efficacy

Author

Sweid, Ahmad, primary, Herial, Nabeel, additional, Sajja, Kalyan, additional, Chalouhi, Nohra, additional, Velagapudi, Lohit, additional, Doermann, Allison, additional, Kardon, Adam, additional, Tjoumakaris, Stavropoula, additional, Zarzour, Hekmat, additional, Smith, Michelle J, additional, Choe, Hana, additional, Shah, Qaisar, additional, Mackenzie, Larami, additional, Kozak, Osman, additional, Rosenwasser, Robert H, additional, Jabbour, Pascal, additional, and Gooch, M Reid, additional

Published
2020
Full Text
View/download PDF

21. Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial

Author

Hill, Michael D, primary, Goyal, Mayank, additional, Menon, Bijoy K, additional, Nogueira, Raul G, additional, McTaggart, Ryan A, additional, Demchuk, Andrew M, additional, Poppe, Alexandre Y, additional, Buck, Brian H, additional, Field, Thalia S, additional, Dowlatshahi, Dar, additional, van Adel, Brian A, additional, Swartz, Richard H, additional, Shah, Ruchir A, additional, Sauvageau, Eric, additional, Zerna, Charlotte, additional, Ospel, Johanna M, additional, Joshi, Manish, additional, Almekhlafi, Mohammed A, additional, Ryckborst, Karla J, additional, Lowerison, Mark W, additional, Heard, Kathy, additional, Garman, David, additional, Haussen, Diogo, additional, Cutting, Shawna M, additional, Coutts, Shelagh B, additional, Roy, Daniel, additional, Rempel, Jeremy L, additional, Rohr, Axel CR, additional, Iancu, Daniela, additional, Sahlas, Demetrios J, additional, Yu, Amy Y X, additional, Devlin, Thomas G, additional, Hanel, Ricardo A, additional, Puetz, Volker, additional, Silver, Frank L, additional, Campbell, Bruce C V, additional, Chapot, René, additional, Teitelbaum, Jeanne, additional, Mandzia, Jennifer L, additional, Kleinig, Timothy J, additional, Turkel-Parrella, David, additional, Heck, Donald, additional, Kelly, Michael E, additional, Bharatha, Aditya, additional, Bang, Oh Young, additional, Jadhav, Ashutosh, additional, Gupta, Rishi, additional, Frei, Donald F, additional, Tarpley, Jason W, additional, McDougall, Cameron G, additional, Holmin, Staffan, additional, Rha, Joung-Ho, additional, Puri, Ajit S, additional, Camden, Marie-Christine, additional, Thomalla, Götz, additional, Choe, Hana, additional, Phillips, Stephen J, additional, Schindler, Joseph L, additional, Thornton, John, additional, Nagel, Simon, additional, Heo, Ji Hoe, additional, Sohn, Sung-Il, additional, Psychogios, Marios-Nikos, additional, Budzik, Ronald F, additional, Starkman, Sidney, additional, Martin, Coleman O, additional, Burns, Paul A, additional, Murphy, Seán, additional, Lopez, George A, additional, English, Joey, additional, Tymianski, Michael, additional, Demchuk, Andrew, additional, Barber, Philip, additional, Smith, Eric, additional, Bal, Simerpreet, additional, Subramaniam, Suresh, additional, Peters, Steven, additional, Couillard, Phillippe, additional, Klein, Gary, additional, Stys, Peter, additional, Menon, Bijoy, additional, Coutts, Shelagh, additional, Almekhlafi, Mohammed, additional, Hill, Michael, additional, Wong, John, additional, Mitha, Alim, additional, Eesa, Muneer, additional, Morrish, William, additional, Alqatani, Saad, additional, Kashani, Nima, additional, Ospel, Johanna, additional, Venkatesan, Prasanna, additional, Teleg, Erika, additional, Sitaram, Amith, additional, Graham, Brett, additional, Van Gaal, Stephen, additional, Moussaddy, Aimen, additional, Chakraborty, Debabrata, additional, Maraj, Nicholas, additional, Loockey, Andrew, additional, Chen, Shuo, additional, Singh, Ravinder, additional, Alsultan, Abdulaziz, additional, Asuncion, Ria, additional, Tse, Dominic, additional, Doshi, Darshan, additional, Volny, Ondrej, additional, Ojha, Piyush, additional, Wadhwa, Ankur, additional, Marko, Martha, additional, Singh, Nishita, additional, Wasyliw, Sanchea, additional, Ryckborst, Karla, additional, Kenney, Carol, additional, Save, Supriya, additional, Jambula, Anitha, additional, Newcommon, Nancy, additional, Hull, Gavin, additional, Blackstock, Darcy, additional, Kiszczak, Sharon, additional, Zimmel, Leslie, additional, Wright, Michelle, additional, Jahraus, Cari, additional, Andersen, Linda, additional, Bohn, Shelly, additional, Paul, Joseph, additional, Zhang, Oiao, additional, Doram, Craig, additional, Lowerison, Mark, additional, Hanley, Andrea, additional, Campbell, Lori, additional, Ure, Ashley, additional, Taylor, Francis, additional, Hul, Dominic, additional, Wiebe, Samuel, additional, Saluzzi, Marina, additional, Blenkin, Nicole, additional, Frayne, Richard, additional, Buck, Brian, additional, Butcher, Kenneth, additional, Shuaib, Ashfaq, additional, Jeerakathil, Tom, additional, Jickling, Glen, additional, Emery, Derek, additional, Rempel, Jeremy, additional, Owen, Richard, additional, Ashforth, Robert, additional, Yeo, Tom, additional, Kotylak, Trevor, additional, O'Kelly, Cian, additional, Chow, Michael, additional, Siddiqui, Muzaffer, additional, Saqqur, Maher, additional, D'Souza, Atlantic, additional, Lloret, Mar, additional, Butt, Asif, additional, Nomani, Ali, additional, Kalashyan, Hayrapet, additional, Thirunavukkarasu, Sibi, additional, Jabs, Juline, additional, Fairall, Paige, additional, Piquette, Lori, additional, Phillips, Stephen, additional, Green, A. Laine, additional, Gubitz, Gordon, additional, Heidenreich, Jens, additional, Huynh, Thien, additional, Shankar, Jai, additional, Maloney, William, additional, Vandorpe, Robert, additional, Schmidt, Matthias, additional, Pickett, Gwynedd, additional, Weeks, Adrienne, additional, Jarrett, Judith, additional, MacDonald, Debbie, additional, Arsenault, Joanna, additional, Kinnear, Ruth, additional, Mandzia, Jennifer, additional, Mayich, Michael, additional, Boulton, Melfort, additional, Bullrich, Maria, additional, Fridman, Sebastian, additional, Kiwan, Ruba, additional, Lee, Donald, additional, Lownie, Stephen, additional, Khaw, Alexander, additional, Pandey, Sachin, additional, Sharma, Manas, additional, Sposato, Luciano, additional, Wade, Kevin, additional, Beauchamp, Beth, additional, Lambourn, Lindsay, additional, Amato-Marziali, Belinda, additional, Poppe, Alexandre, additional, Daneault, Nicole, additional, Deschaintre, Yan, additional, Gioia, Laura, additional, Jacquin, Grégory, additional, Odier, Céline, additional, Stapf, Christian, additional, Raymond, Jean, additional, Weill, Alain, additional, Lapierre, Marlène, additional, Jadil, Nadia, additional, Jolteus, Judlène, additional, Angle, Mark, additional, Hannouche, Mathew, additional, Badawy, Mohamed, additional, Letourneau, Justin, additional, Cortes, Maria, additional, Linnell, Grant, additional, Tampieri, Donateela, additional, Vieira, Lucy, additional, Legault, Catherine, additional, Durcan, Liam, additional, Moore, Angela, additional, Cole, Erin, additional, Magnussen, Claire, additional, Salmon, Kristiana, additional, Khalil, Salma, additional, Desloges, Isabelle, additional, Waxman, Lindsay, additional, Abdon, Wynne, additional, Lai, Sonia, additional, Shamy, Michel, additional, Stotts, Grant, additional, Blacquiere, Dylan, additional, Lesiuk, Howard, additional, Quateen, Aiman, additional, Drake, Brian, additional, Dewar, Brian, additional, Daham, Zeinab, additional, Kelly, Michael, additional, Hunter, Gary, additional, Peeling, Lissa, additional, Whelan, Ruth, additional, Garner, Aaron, additional, Urroz, Lilian, additional, Maley, Sharleen, additional, Silver, Frank, additional, Casaubon, Leanne, additional, Pikula, Aleksandra, additional, Del Campo, Martin, additional, Schaafsma, Joanna, additional, Jaigobin, Cheryl, additional, Krings, Timo, additional, Pereira, Vitor, additional, Agid, Ronit, additional, Farb, Richard, additional, Kalman, Libby, additional, Cayley, Anne, additional, Williams, Janice, additional, Stewart, Tim, additional, Misquitta, Karen, additional, Selchen, Daniel, additional, Marotta, Thomas, additional, Sarma, Dipanka, additional, Montanera, Walter, additional, Spears, Juluan, additional, Saposnik, Gustavo, additional, Kostyrko, Pawel, additional, Li, Yangmei, additional, Parra-Farina, Carmen, additional, Bengzon Diestro, Jose Danilo, additional, Verreault, Steve, additional, Mackey, Ariane, additional, Audet, Marie-Eve, additional, Milot, Geneviève, additional, Lavoie, Pascale, additional, Gariépy, Jean-Luc, additional, Collard, Karine, additional, Haché, Annette, additional, Van Adel, Brian, additional, Sahlas, Demetrios, additional, Alshanbari, Ahmed, additional, Baldwin, Josephine, additional, Catanese, Luciana, additional, Chen, Bing, additional, De Sa Boasquevisque, Danielle, additional, Deshmukh, Aviraj, additional, Knapman, Jordan, additional, Lamers, Shana, additional, Larrazabal, Ramiro, additional, MacMillan, Susan, additional, Mai, Lauren, additional, Mattia, Alicia, additional, Nayar, Sumiti, additional, Ng, Kuan, additional, Oczkowski, Wieslaw, additional, Perera, Kanjana, additional, Shawawrah, Mays, additional, Shoamanesh, Ashkan, additional, Sobhi, Gita, additional, Syed, Nabeel, additional, Taher, Noran, additional, Vandervelde, Cheyanne, additional, Wang Pharm, Di, additional, Field, Thalia, additional, Teal, Philip, additional, Benavente, Oscar, additional, Wilson, Laura, additional, Mann, Sharanpal, additional, Yip, Samuel, additional, Murphy, Colleen, additional, Heran, Manraj, additional, Rohr, Axel, additional, Settecase, Fabio, additional, Redekop, Gary, additional, Haw, Charles, additional, Maclean, Genoveva, additional, Murray, Karina, additional, Chiu, Rosalin, additional, Flexman, Alana, additional, Strecha, Eilidh, additional, Gayton, Yolanda, additional, Yip, Judy, additional, Swartz, Richard, additional, Boulos, Mark, additional, Gladstone, David, additional, Yu, Amy, additional, Hopyan, Julia, additional, Khosravani, Houman, additional, Manosalva Alzate, Herbert, additional, Southwell, Alisia, additional, Kamra, Maneesha, additional, Lopes, Kaitlyn, additional, Kapoor, Arunima, additional, da Costa, Leodante, additional, Yang, Victor, additional, Dyer, Erin, additional, Shah, Ruchir, additional, Knowles, Brenda, additional, Nichols, Jennifer, additional, Patterson, Jennifer, additional, Cope, Krista, additional, Dickerson, Lee, additional, Barton, Katrina, additional, Gray, Kimberly, additional, Massengale, Ticey, additional, Miller, Melanie, additional, Simpson, Cindy, additional, Walker, Sabrina, additional, Tennyson-Yemm, Chlin, additional, Devlin, Thomas, additional, Frei, Donald, additional, Bellon, Richard, additional, Atchie, Benjamin, additional, Kaminsky, Ian, additional, Wilson, Duandelyn, additional, Schraeder, Nicolle, additional, Arias, Eric, additional, Kodis, Lisa, additional, Talley, Mark, additional, Edinger, Alex, additional, Talley, Tiffany, additional, Dempsey, Ita, additional, Williams, Laurie, additional, Williams, Scott, additional, Kupniewski, Sonny, additional, Fasbinder, Brad, additional, Snead, Joanna, additional, Mackenzie, Larami, additional, Weisman, Davi, additional, Kozak, Osman, additional, Shah, Qaisar, additional, Gzesh, Dan, additional, Kulandaivel, Kandan, additional, Khoury, John, additional, Klein, Brad, additional, Bussinger, Patricia, additional, Griffin, Lisa, additional, dePalmo, Ashley, additional, Oliva, Cynthia, additional, Jovin, Tudor, additional, Kenmuir, Cynthia, additional, Jankowitz, Brian, additional, Gross, Bradley, additional, Rocha, Marcelo, additional, Starr, Matthew, additional, Brown, Merritt, additional, Hawkes, Christine, additional, Shah, Kavit, additional, Tememe, Danoushka, additional, Walker, Gregory, additional, Patel, Pratit, additional, Klein, Bradley, additional, Ziayee, Habibullah, additional, Limaye, Kaustubh, additional, Baxendell, Lisa, additional, Gilchrist, Vicki, additional, Feineigle, Patricia, additional, Toseki Haibach, Kelsea, additional, Van Every, Cathy, additional, Desai, Shashyat, additional, Zulfiqar, Maryam, additional, Gibson, Linda, additional, Barrett, Sean, additional, Arcot, Karthikeyan, additional, DiCrescento, Steven, additional, Farkas, Jeffrey, additional, Filipowski, Gregory, additional, Frontera, Jennifer, additional, Joset, Danielle, additional, Liff, Jeremy, additional, Scher, Erica, additional, McDougall, Cameron, additional, Kelly, Cheryl, additional, Patel, Akshal, additional, Monteith, Stephen, additional, Atchaneeyasakul, Kunakorn, additional, Burgos, Adrian, additional, Chua, Janice Anne, additional, Gaines, Nathan, additional, Grunberg, Ileana, additional, Guzy, Judy, additional, Liu, Zuolu, additional, Maluste, Neil, additional, Ramirez, Lucas, additional, Sharma, Latisha, additional, Brown, Morry, additional, McDonald, Colin, additional, Calderon, Mateo, additional, Hargis, Mitch, additional, Roels, Christina, additional, Emmady, Prabhu, additional, Alvi, Talat, additional, McTaggart, Ryan, additional, Jayaraman, Mahesh, additional, Cutting, Shawna, additional, Smith, Wendy, additional, Foley, Susan, additional, Paolucci, Gino, additional, Has, Richard, additional, Quinn, Katie, additional, Fuller, Lindsey, additional, Brierley, Rebecca, additional, Watkins, Christina, additional, Demir, Nicole, additional, Lopez, George, additional, Vargas, Alejandro, additional, Osteraas, Nicholas, additional, Holtz, Becky, additional, Hanel, Ricardo, additional, Aghaebrahim, Amin, additional, Chmayssani, Mohamad, additional, Naval, Neeraj, additional, Day, Jason, additional, Dellorso, Scott, additional, Ludwig, Benjamin, additional, Schemmel, Derek, additional, Ebreo, Nancy, additional, Bell, Karen, additional, Lewis, Lanai, additional, Delucia, Marjorie, additional, Nogueira, Raul, additional, Frankel, Michael, additional, Bhatt, Nirav, additional, Bianchi, Nicolas, additional, Anderson, Aaron, additional, Belagaje, Samir, additional, Liberato, Bernardo, additional, Rangaraju, Srikant, additional, Al-Bayati, Alhamza, additional, Grossberg, Jonathan, additional, Craft, Leah, additional, Schindler, Kiva, additional, Schaad, Erin, additional, Schultz, Meagan, additional, Southerly, Lorretta, additional, Doppelheuer, Shannon, additional, Charlton, Jacquelyn, additional, Faggard, Jason, additional, Barbret, Zuzana, additional, DukSoo Han, Ethan, additional, Walters, Robin, additional, Dolia, Jaydevsinh, additional, El-Jamal, Sleiman, additional, Eby, Brendan, additional, Saleem, Yasir, additional, Pearl, Harrison, additional, Patel, Kishan, additional, Rahman, Haseeb, additional, Butt, Reema, additional, English, Stephen, additional, Puri, Ajit, additional, Howk, Mary, additional, Singh, Jasmeet, additional, Massari, Francesco, additional, DeMacedo Rodrigues, Katyucia, additional, Kuhn, Anna, additional, Barazangi, Nobl, additional, Telischak, Nick, additional, Kim, Warren, additional, Ross, Josh, additional, DeVole, Nata, additional, Redford, Jessica, additional, Ferreira, Milena, additional, Ponting, Katie, additional, Shen, Helen, additional, Bedenk, Ann, additional, Patel, Susila, additional, Fernandess, Julia, additional, Ke, Michael, additional, Spokoyny, Ilanit, additional, Gao, Billy, additional, Tong, David, additional, Chen, Charlene, additional, Wong, Christine, additional, Choe, Jessica, additional, Martin, Coleman, additional, Summers, Debbie, additional, Boutwell, Christine, additional, Olds, Karin, additional, Crandall, Suzanne, additional, Eatman, John, additional, Akhtar, Naveed, additional, Holloway, William, additional, Halpin, Jared, additional, Donegan, Brett, additional, Schindler, Joseph, additional, Hwang, David, additional, Gilmore, Emily, additional, Petersen, Nils, additional, Sheth, Kevin, additional, Brown, Stacy, additional, Beekman, Rachel, additional, George, Benjamin, additional, Kaddouh, Firas, additional, Falcone, Guido, additional, Wira, Charles, additional, Matouk, Charles, additional, Loomis, Caitlin, additional, Amin, Hardik, additional, Stretz, Hans Christoph, additional, Narula, Reshma, additional, Jasne, Adam, additional, Sansing, Lauren, additional, Agarwal, Tijil, additional, Jasak, Sara, additional, Fontaine, Briana, additional, King, Zachary, additional, Kuohn, Lindsey, additional, Orgass, Hailey, additional, Leary, Megan, additional, Nye, Joan, additional, Halbert, Kelsey, additional, Nystrom, Karin, additional, Neuschatz, Kaile, additional, Petrucci, Dawn, additional, Coppola, Anna, additional, Tarpley, Jason, additional, Joyce, Treasure, additional, Hou, Sam, additional, Umekubo, Mark, additional, Nakamura, Catrice, additional, Ovando, Renee, additional, Zuniga, Diana, additional, Nien, Yih Lin, additional, Basto, Fernando Mayor, additional, Arch, Allison, additional, Jong, Laura, additional, Conrad, William, additional, Abbott, Tara, additional, Yao, Jay, additional, Caganap, Scott, additional, Jordan, John, additional, Teitelbaum, George, additional, Darflinger, Robert, additional, Bain, Marianne, additional, Budzik, Ronald, additional, Czerniak, Jennifer, additional, Groezinger, Katherine, additional, Hicks II, William, additional, Kaskar, Omran, additional, Katz, Brian, additional, Loochtan, Aaron, additional, Pema, Peter, additional, Rai, Vivek, additional, Vora, Nirav, additional, Brown, Amanda, additional, Goodman, Diane, additional, Danenbergs, Barb, additional, Gossett, Monica, additional, Chung, Jong-Won, additional, Jeon, Pyoung, additional, Kim, Keon Ha, additional, Lim, Yun Jeong, additional, Nam, Hyo Suk, additional, Kim, Young Dae, additional, Park, HyungJong, additional, Hwang, In Gun, additional, Ha, Wooseok, additional, Choi, Jin Kyo, additional, Jeong, Kyungsun, additional, Park, Hee-Kwon, additional, Yoon, Cindy, additional, Kim, Bo-Kyung, additional, Kim, Chang-hyun, additional, Yoo, Joonsang, additional, Hong, Jeong-Ho, additional, Park, Hyungjong, additional, Kim, Sohyeon, additional, Choi, Moonkyung, additional, Bae, Hyoeun, additional, Lee, Jun Seok, additional, Lee, Jae-Joon, additional, Jun, Go-Eun, additional, Jeon, Sujeong, additional, Campbell, Bruce, additional, Mitchell, Peter, additional, Yassi, Nawaf, additional, Davis, Stephen, additional, Donnan, Geoffrey, additional, Parsons, Mark, additional, Yan, Bernard, additional, Dowling, Richard, additional, Bush, Steven, additional, Wu, Teddy, additional, Shah, Darshan, additional, Zhao, Henry, additional, Salvaris, Patrick, additional, Alemseged, Fana, additional, Ng, Felix, additional, Williams, Cameron, additional, Balabanski, Anna, additional, Dos Santos, Angela, additional, Ng, Jo-Lyn, additional, McDonald, Amy, additional, Jackson, David, additional, Tsoleridis, Jessica, additional, Pesavento, Lauren, additional, Kleinig, Timothy John, additional, Nurs, Roy Drew, additional, Cranefield, Jennifer, additional, Scroop, Rebecca, additional, Cagi, Lavenia, additional, Harvey, Jackson, additional, Waters, Michael, additional, Brennan, Robert, additional, O'Hare, Alan, additional, Power, Sarah, additional, Williams, David, additional, Boyle, Karl, additional, Moynihan, Barry, additional, Liddy, Ann-Marie, additional, Large, Margaret, additional, Cullen, Ailbhe, additional, Walsh, Roisin, additional, Martin, Emma, additional, Lynch, Julie, additional, McElroy, Sinéad, additional, Coveney, Sarah, additional, Deegan, Caroline, additional, Horgan, Gillian, additional, Kelly, Peter, additional, Laffan, Aoife, additional, Llamas-Osorio, Yudy, additional, Lynch, Catherine, additional, Mac Mahon, Peter, additional, Marnane, Michael, additional, McCabe, John, additional, Burns, Paul, additional, Tauro, Suzanne, additional, Cuddy, Sarah, additional, Rennie, Ian, additional, Smyth, Graham, additional, Flynn, Peter, additional, Wiggam, Ivan, additional, Kerr, Enda, additional, Gordon, Patricia, additional, Fearon, Patricia, additional, Roberts, Geralt, additional, Patterson, Cathy, additional, Adams, Karen, additional, Wells, Brian, additional, McFarland, Margaret, additional, Moreira, Tiago, additional, Sjöstrand, Christina, additional, Mazya, Michael, additional, Almqvist, Håkan, additional, Wahlgren, Nils, additional, Steinberg, Anna, additional, Cooray, Charith, additional, Eriksson, Einar, additional, Thorén, Magnus, additional, Keselman, Boris, additional, Ahmed, NIaz, additional, Holmberg, Åke, additional, Axelsson, Maria, additional, Berglund, Annika, additional, Golsari, Amir, additional, Hoppe, Julia, additional, Deb-Chatterji, Milani, additional, Cheng, Bastian, additional, Barrow, Ewgenia, additional, Schlemm, Eckhard, additional, Lettow, Iris, additional, Jensen, Märit, additional, Otto, Dagmar, additional, Jaramillo, Kirsten, additional, Appelbohm, Hannes, additional, Fiehler, Jens, additional, Bester, Maxim, additional, Schönfeld, Michael, additional, Brekenfeld, Caspar, additional, Holst, Brigitte, additional, Wortmann, Ginette, additional, Koch, Friederike, additional, Gerber, Johannes, additional, Abramyuk, Andrij, additional, Kaiser, Daniel, additional, Winzer, Simon, additional, Prakapenia, Alexandra, additional, Pallesen, Lars-Peder, additional, Siepmann, Timo, additional, Barlinn, Kristian, additional, Haase, Kathrin, additional, Sauer, Angela, additional, Liman, Jan, additional, Brehm, Alex, additional, Maus, Volker, additional, Hollstein, Nicole, additional, Reinke, Annika, additional, Neitz, Gustav, additional, Schnieder, Marlena, additional, Schwarz, Margret, additional, Ibrahim, Allam, additional, Müller, Julia, additional, Meister, Stefanie, additional, Bäumle, Berit, additional, Pilgram-Pastor, Sara, additional, Wallocha, Marta, additional, Stauder, Michael, additional, Celik, Ekin, additional, Stracke, Paul, additional, Müller, Nicole, additional, Weber, Ralph, additional, Velktamp, Roland, additional, Ringleb, Peter Arthur, additional, Heyse, Miriam, additional, Amiri, Hemasse, additional, Mundiyanapurath, Sibu, additional, Chen, Min, additional, Bevrle, Elisabeth, additional, Beck, Perdita, additional, Möhlenbruch, Markus alfred, additional, Potvin, Alphonse, additional, Harris, Cameron, additional, Wang, Chong, additional, Adams, Corey, additional, Mayor, Diana, additional, Garman, Dave, additional, Chau, Davis, additional, Wu, Jane, additional, Lunn, Janet, additional, Bermanis, Liat, additional, Teyes, Lucy, additional, Constant, Marc, additional, Galsim, Maria, additional, Helbin, Michael, additional, Leroux, Michelle, additional, Felix, Nicole, additional, Bendre, Nilima, additional, Cuthbert, Sandra, additional, Brokx, Steve, additional, Zhang, Yichuan, additional, Lingham, Trudy, additional, Kohli, Yatika, additional, Salter, Michael, additional, Liebeschuetz, Joseph, additional, Hofmann, Frieder, additional, Constant, John, additional, Soeder, Tom, additional, Snoke, Kara, additional, Bologa, Monica, additional, Stahl, Kimberly, additional, and Graziewicz, Maria, additional

Published
2020
Full Text
View/download PDF

23. Changes in Neuroendovascular Procedural Volume During the COVID‐19 Pandemic: An International Multicenter Study.

Author

Qureshi, Adnan I., Agunbiade, Samiat, Huang, Wei, Akhtar, Iqra N., Abraham, Michael G., Akhtar, Naveed, Al‐Mufti, Fawaz, Aytac, Emrah, Balgetir, Ferhat, Grigoryan, Mikayel, Gomez, Camilo R., Hassan, Ameer E., Jani, Vishal, Janjua, Nazli A., Jiao, Liqun, Khatri, Rakesh, Kirmani, Jawad F., Kobayashi, Adam, Kozak, Osman, and Lee, Jun

Subjects
COVID-19 pandemic, COVID-19, PANDEMICS, INTRACRANIAL aneurysm ruptures, CEREBRAL arteriovenous malformations, INTRACRANIAL aneurysms, ENDOVASCULAR surgery
Abstract

BACKGROUND AND PURPOSE: The effect of coronavirus disease 2019 (COVID‐19) pandemic on performance of neuroendovascular procedures has not been quantified. METHODS: We performed an audit of performance of neuroendovascular procedures at 18 institutions (seven countries) for two periods; January‐April 2019 and 2020, to identify changes in various core procedures. We divided the region where the hospital was located based on the median value of total number of COVID‐19 cases per 100,00 population‐into high and low prevalent regions. RESULTS: Between 2019 and 2020, there was a reduction in number of cerebral angiograms (30.9% reduction), mechanical thrombectomy (8% reduction), carotid artery stent placement for symptomatic (22.7% reduction) and asymptomatic (43.4% reduction) stenoses, intracranial angioplasty and/or stent placement (45% reduction), and endovascular treatment of unruptured intracranial aneurysms (44.6% reduction) and ruptured (22.9% reduction) and unruptured brain arteriovenous malformations (66.4% reduction). There was an increase in the treatment of ruptured intracranial aneurysms (10% increase) and other neuroendovascular procedures (34.9% increase). There was no relationship between procedural volume change and intuitional location in high or low COVID‐19 prevalent regions. The procedural volume reduction was mainly observed in March‐April 2020. CONCLUSIONS: We provided an international multicenter view of changes in neuroendovascular practices to better understand the gaps in provision of care and identify individual procedures, which are susceptible to change. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

29. Association of Reperfusion and Procedural Characteristics with Endovascular Thrombectomy Outcomes in Large Core Stroke: Sub‐Analysis from the SELECT2 Trial.

Author

Hassan, Ameer E., Abraham, Michael G., Blackburn, Spiros, Hussain, Muhammad S., Ortega‐Gutierrez, Santiago, Chen, Michael, Hu, Yin C., Pujara, Deep K., Herial, Nabeel A., Tsai, Jenny P., Budzik, Ronald F., Manning, Nathan W., Kozak, Osman, Hanel, Ricardo A., Aghaebrahim, Amin N., Gandhi, Chirag D., Al‐Mufti, Fawaz, Cheung, Andrew, Yan, Bernard, and Mitchell, Peter

Subjects
*ENDOVASCULAR surgery, *CEREBRAL infarction, *RANDOMIZED controlled trials, *STROKE, *REPERFUSION
Abstract

Methods Results Interpretation Endovascular thrombectomy (EVT) was shown to be safe and efficacious in patients with large core stroke in multiple randomized controlled trials. However, the impact of reperfusion and other procedural metrics on EVT outcomes in this population has not been well‐characterized.From the SELECT2 trial, we evaluated the association between reperfusion status, first‐pass effect (near‐complete or complete reperfusion [extended thrombolysis in cerebral infarction (eTICI) 2c‐3] in 1 pass), procedure time and primary technique (aspiration vs stent‐retriever) with functional outcomes in patients receiving EVT across ASPECTS (3 vs 4 vs 5) and core estimate strata (<70 vs ≥70ml, <100 vs ≥100ml, and <150 vs ≥150ml).Of 180 patients who received thrombectomy, 144 (80%) achieved successful reperfusion (eTICI 2b‐3) and demonstrated better clinical outcomes (adjusted generalized odds ratios [aGenOR]: 1.48, 95% confidence interval [CI]: 1.01–2.15), compared with unsuccessful reperfusion. Results were consistent across ASPECTS and core estimate strata. Additionally, complete or near‐complete reperfusion (eTICI 2c‐3) was associated with better functional outcome (aGenOR: 1.99, 95% CI: 1.33–2.97) in patients achieving successful reperfusion. Functional outcome point estimates favored those with first‐pass‐effect (42 of 167 (25%), aGenOR: 1.46, 95% CI: 0.96–2.24). Longer procedure time was associated with worse modified Rankin scale (mRS) distribution (aGenOR: 0.92, 95% CI: 0.87–0.96, p‐value = 0.001 for 10 minutes increment). Aspiration‐first technique was used in 43 of 154 (25%) patients and was not associated with higher reperfusion (88% vs 78%, p = 0.18) or better functional outcome (aGenOR: 0.74, 95% CI: 0.50–1.10) as compared with stent‐retriever first.Successful reperfusion resulted in improved clinical outcomes in large core patients across baseline ischemic core strata. Near complete or complete reperfusion was further associated with better outcomes, whereas prolonged procedures were associated with worse outcomes. Results were consistent regardless of the technique used. ANN NEUROL 2024 [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

31. Contributors

Author

Anderson, Robert J., Balk, Robert A., Barie, Philip S., Barletta, Jeffrey F., Barton, Richard G., Bartter, Thaddeus, Bashour, C. Allen, Beale, Richard, Bekes, Carolyn, Bion, Julian, Bleck, Thomas P., Borunda, Delia, Braithwaite, Susan S., Browne, William T., Buckley, John D., Caironi, Pietro, Carlesso, Eleonora, Caronna, John J., Chansky, Michael, Chaptini, Louis, Cilley, Jonathan H., Jr., Cinel, Ismail, Crnich, Christopher J., Curti, Brendan D., Danis, Marion, Dellinger, R. Phillip, Devlin, John W., Dinh, Jack T., Domínguez-Cherit, Guillermo, Dries, David J., Elfant, Adam B., Ely, E. Wesley, Emanuel, Ezekiel, Faridi, Ahmad Bilal, Farmer, J. Christopher, Fraimow, Henry S., Friedman, Yaakov, Garwood, Susan, Gattinoni, Luciano, Gautam, Nandan, Gessman, Lawrence J., Ginsberg, Fredric, Godke, John, Goldman, H. Warren, Groeneveld, A.B.J., Gross, Robin, Gurka, David P., Haddad, Ghada, Haupt, Marilyn T., Hockstein, Michael J., Hollenberg, Steven M., Hudson, Leonard D., Hunninghake, Gary W., Jackson, James, Jamison, C.A., Jean, Smith, Jneid, Hani, Johnson, Robert G., Jubran, Amal, Kanagasundaram, Nigel S., Karam, George, Karam, Joseph A., Karnik, Ankur A., Karnik, Ashok M., Kincaid, M. Sean, Kozak, Osman Samil, Kumar, Anand, Lachant, Neil A., Laghi, Franco, Lapinsky, Stephen E., Lavery, G.G., Longo, Dan L., Lotano, Ramya, Lotano, Vincent E., Luce, John M., Luce, Judith A., Maki, Dennis G., March, Robert J., Maree, Andrew O., Marini, John, Marshall, John C., Masur, Henry, McFadden, Christopher, Metnitz, Philipp G.H., Mirsen, Thomas R., Moreno, Rui P., Murphy, Nick, Murray, Michael J., Nagueh, Sherif F., Niederman, Michael S., Ostrosky-Zeichner, Luis, Ouellette, Daniel R., Ougorets, Igor, Oyen, Lance J., Paganini, Emil P., Palacios, Igor F., Pandharipande, Pratik, Parrillo, Joseph E., Patel, Amish, Peikin, Steven, Peruzzi, William, Peters, Priscilla J., Popovich, John, Jr., Posadas-Calleja, Juan Gabriel, Pratter, Melvin R., Rajaram, S. Sujanthy, Reay, Hannah, Reboli, Annette C., Rex, John H., Rhodes, Andrew, Rubin, Lewis J., Rudis, Maria, Safdar, Nasia, Saffle, Jeffrey R., Sahn, Steven A., Schmidt, Gregory A., Sharar, Sam R., Silverman, Henry, Sobek, Sabine, Strange, Charlie, Subramanian, Sanjay, Tang, Wanchun, Taylor, Robert W., Teo, Boon Wee, Tobin, Martin J., Townsend, Sean, Trohman, Richard, Trzeciak, Stephen, Turi, Zoltan G., Turtz, Alan R., Vincent, Jean-Louis, Weil, Max Harry, Weisberg, Lawrence S., Werns, Steven, Wijdicks, Eelco F.M., Zanotti-Cavazzoni, Sergio L., and Zimmerman, Janice L.

Full Text
View/download PDF

32. Endovascular Thrombectomy for Large Ischemic Stroke Across Ischemic Injury and Penumbra Profiles.

Author

Sarraj A, Hassan AE, Abraham MG, Ortega-Gutierrez S, Kasner SE, Hussain MS, Chen M, Churilov L, Johns H, Sitton CW, Yogendrakumar V, Ng FC, Pujara DK, Blackburn S, Sundararajan S, Hu YC, Herial NA, Arenillas JF, Tsai JP, Budzik RF, Hicks WJ, Kozak O, Yan B, Cordato DJ, Manning NW, Parsons MW, Cheung A, Hanel RA, Aghaebrahim AN, Wu TY, Portela PC, Gandhi CD, Al-Mufti F, Pérez de la Ossa N, Schaafsma JD, Blasco J, Sangha N, Warach S, Kleinig TJ, Shaker F, Al Shaibi F, Toth G, Abdulrazzak MA, Sharma G, Ray A, Sunshine J, Opaskar A, Duncan KR, Xiong W, Samaniego EA, Maali L, Lechtenberg CG, Renú A, Vora N, Nguyen T, Fifi JT, Tjoumakaris SI, Jabbour P, Tsivgoulis G, Pereira VM, Lansberg MG, DeGeorgia M, Sila CA, Bambakidis N, Hill MD, Davis SM, Wechsler L, Grotta JC, Ribo M, Albers GW, and Campbell BC

Subjects
Adult, Humans, Female, Aged, Male, Thrombectomy adverse effects, Thrombectomy methods, Brain diagnostic imaging, Stroke diagnostic imaging, Stroke surgery, Ischemic Stroke diagnostic imaging, Ischemic Stroke surgery, Brain Ischemia diagnostic imaging, Brain Ischemia surgery
Abstract

Importance: Whether endovascular thrombectomy (EVT) efficacy for patients with acute ischemic stroke and large cores varies depending on the extent of ischemic injury is uncertain., Objective: To describe the relationship between imaging estimates of irreversibly injured brain (core) and at-risk regions (mismatch) and clinical outcomes and EVT treatment effect., Design, Setting, and Participants: An exploratory analysis of the SELECT2 trial, which randomized 352 adults (18-85 years) with acute ischemic stroke due to occlusion of the internal carotid or middle cerebral artery (M1 segment) and large ischemic core to EVT vs medical management (MM), across 31 global centers between October 2019 and September 2022., Intervention: EVT vs MM., Main Outcomes and Measures: Primary outcome was functional outcome-90-day mRS score (0, no symptoms, to 6, death) assessed by adjusted generalized OR (aGenOR; values >1 represent more favorable outcomes). Benefit of EVT vs MM was assessed across levels of ischemic injury defined by noncontrast CT using ASPECTS score and by the volume of brain with severely reduced blood flow on CT perfusion or restricted diffusion on MRI., Results: Among 352 patients randomized, 336 were analyzed (median age, 67 years; 139 [41.4%] female); of these, 168 (50%) were randomized to EVT, and 2 additional crossover MM patients received EVT. In an ordinal analysis of mRS at 90 days, EVT improved functional outcomes compared with MM within ASPECTS categories of 3 (aGenOR, 1.71 [95% CI, 1.04-2.81]), 4 (aGenOR, 2.01 [95% CI, 1.19-3.40]), and 5 (aGenOR, 1.85 [95% CI, 1.22-2.79]). Across strata for CT perfusion/MRI ischemic core volumes, aGenOR for EVT vs MM was 1.63 (95% CI, 1.23-2.16) for volumes ≥70 mL, 1.41 (95% CI, 0.99-2.02) for ≥100 mL, and 1.47 (95% CI, 0.84-2.56) for ≥150 mL. In the EVT group, outcomes worsened as ASPECTS decreased (aGenOR, 0.91 [95% CI, 0.82-1.00] per 1-point decrease) and as CT perfusion/MRI ischemic core volume increased (aGenOR, 0.92 [95% CI, 0.89-0.95] per 10-mL increase). No heterogeneity of EVT treatment effect was observed with or without mismatch, although few patients without mismatch were enrolled., Conclusion and Relevance: In this exploratory analysis of a randomized clinical trial of patients with extensive ischemic stroke, EVT improved clinical outcomes across a wide spectrum of infarct volumes, although enrollment of patients with minimal penumbra volume was low. In EVT-treated patients, clinical outcomes worsened as presenting ischemic injury estimates increased., Trial Registration: ClinicalTrials.gov Identifier: NCT03876457.

Published
2024
Full Text
View/download PDF

33. Posterior reversible encephalopathy syndrome: incidence of atypical regions of involvement and imaging findings.

Author

McKinney AM, Short J, Truwit CL, McKinney ZJ, Kozak OS, SantaCruz KS, and Teksam M

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Female, Humans, Incidence, Male, Middle Aged, Minnesota epidemiology, Risk Factors, Syndrome, Brain Edema epidemiology, Brain Edema pathology, Magnetic Resonance Imaging statistics & numerical data, Risk Assessment methods
Abstract

Objective: Posterior reversible encephalopathy syndrome (PRES) is classically characterized as symmetric parietooccipital edema but may occur in other distributions with varying imaging appearances. This study determines the incidence of atypical and typical regions of involvement and unusual imaging manifestations., Materials and Methods: Seventy-six patients were eventually included as having confirmed PRES from 111 initially suspected cases, per imaging and clinical follow-up. Two neuroradiologists retrospectively reviewed each MR image. Standard sequences were unenhanced FLAIR and T1- and T2-weighted images in all patients, with diffusion-weighted imaging (n = 75) and contrast-enhanced T1-weighted imaging (n = 69) in most. The regions involved were recorded on the basis of FLAIR findings, and the presence of atypical imaging findings (contrast enhancement, restricted diffusion, hemorrhage) was correlated with the severity (extent) of hyperintensity or mass effect on FLAIR., Results: The incidence of regions of involvement was parietooccipital, 98.7%; posterior frontal, 78.9%; temporal, 68.4%; thalamus, 30.3%; cerebellum, 34.2%; brainstem, 18.4%; and basal ganglia, 11.8%. The incidence of less common manifestations was enhancement, 37.7%; restricted diffusion, 17.3%; hemorrhage, 17.1%; and a newly described unilateral variant, 2.6%. Poor correlation was found between edema severity and enhancement (r = 0.072), restricted diffusion (r = 0.271), hemorrhage (r = 0.267), blood pressure (systolic, r = 0.13; diastolic, r = 0.02). Potentially new PRES causes included contrast-related anaphylaxis and alcohol withdrawal., Conclusion: This large series of PRES cases shows that atypical distributions and imaging manifestations of PRES have a higher incidence than commonly perceived, and atypical manifestations do not correlate well with the edema severity.

Published
2007
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results