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Your search keyword '"Koyamada, Nozomi"' showing total 41 results
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41 results on '"Koyamada, Nozomi"'

4. Duodenal neuroendocrine tumor after bilateral breast cancer with type 1 neurofibromatosis: a case report.

Author

Fujiwara, Sho, Koyamada, Nozomi, Miyazawa, Koji, Saiki, Yuriko, Horii, Akira, and Miyazaki, Shukichi

Subjects
DUODENAL tumors, NEUROENDOCRINE tumors, NEUROFIBROMATOSIS 1, BREAST cancer, ABDOMINAL tumors, GASTROINTESTINAL tumors
Abstract

Background: Young women with NF1 are at a high risk of developing breast cancer. Although they are at risk for abdominal tumors, such as gastrointestinal stromal tumors and neuroendocrine tumors, follow-up strategies for other tumors after breast cancer have not yet been established. Here, we present a case of duodenal neuroendocrine tumor found during follow-up after bilateral mastectomy for breast cancer with type 1 neurofibromatosis (NF1), for which pancreaticoduodenectomy (PD) and lymphadenectomy were performed. Case presentation: A 46-year-old woman with NF1 was referred to our hospital for treatment of a duodenal submucosal tumor. Her previous operative history included bilateral mastectomy for breast cancer: right total mastectomy and left partial mastectomy performed 9 and 5 years ago, respectively. Her daughter was confirmed to have NF1, but her parents were unclear. Although she had no recurrence or symptoms during the follow-up for her breast cancer, she wished to undergo 18-fluorodeoxyglucose–positron emission tomography (FDG–PET) for systemic screening. FDG–PET demonstrated FDG accumulation in the duodenal tumor with a maximum standardized uptake value of 5.78. Endoscopy revealed a 20-mm-diameter tumor in the second duodenal portion, and endoscopic biopsy suggested a NET G1. We performed PD and lymphadenectomy for complete. She was doing well without recurrence and was followed up with PET tomography–computed tomography. Conclusions: Early detection of gastrointestinal tumors is difficult, because most of them are asymptomatic. Gastrointestinal screening is important for patients with NF1, and PD with lymphadenectomy is feasible for managing duodenal neuroendocrine tumors, depending on their size. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Successful liver transplantation from agonal non-heart-beating donors in pigs

Author

Sato, Masahide, Ohkohchi, Nobuhiro, Tsukamoto, Shigeki, Koyamada, Nozomi, Asakura, Takeshi, Enomoto, Yoshitaka, Usuda, Masahiro, Miyagi, Shigehito, Okada, Akiho, and Satomi, Susumu

Subjects
Adenosine Triphosphatases, Transplantation, Hot Temperature, L-Lactate Dehydrogenase, Graft Survival, Sus scrofa, Tissue Donors, Heart Arrest, Liver Transplantation, Mitochondria, Microscopy, Electron, Liver, Reperfusion Injury, Animals, Aspartate Aminotransferases, Energy Metabolism
Abstract

An effective way to overcome shortage of donors in liver transplantation (LTx) is to consider such from non-heart-beating donors (NHBDs). We investigated how a liver graft should be treated before and/or after procurement for successful LTx from an NHBD. Porcine LTx was performed with FR167653 (FR), a dual inhibitor of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta), and/or prostaglandin E(1) (PG). Animals were allocated to an FR group (n=4, donors and recipients were treated with FR), a PG group (n=4, donors and recipients were treated with PG), or an FRPG group (n=4, donors and recipients were treated with both FR and PG). No recipients in the FR group and only two of four recipients in the PG group survived, whereas all recipients in the FRPG group survived. Suppression of TNF-alpha and IL-1beta and maintenance of microcirculation are the key to successful transplantation from NHBDs.

Published
2001

22. Successful Use of Anti-CD20 Monoclonal Antibody (Rituximab) for ABO-Incompatible Living-Related Liver Transplantation

Author

Usuda, Masahiro, primary, Fujimori, Keisei, additional, Koyamada, Nozomi, additional, Fukumori, Tatsuya, additional, Sekiguchi, Satoshi, additional, Kawagishi, Naoki, additional, Akamatsu, Yorihiro, additional, Enomoto, Yoshitaka, additional, Satoh, Kazushige, additional, Satoh, Akira, additional, Ishida, Kazuyuki, additional, Moriya, Takuya, additional, and Satomi, Susumu, additional

Published
2005
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34. Viability of Partial Liver Graft from Living Donor in Pigs.

Author

KATOH, HIROTAKA, primary, OHKOHCHI, NOBUHIRO, additional, HIRANO, TAKUJI, additional, SAKURADA, MASATOSHI, additional, ORII, TAKASHI, additional, KOYAMADA, NOZOMI, additional, FUJIMORI, KEISEI, additional, TAKEMURA, MASANOBU, additional, ENDOH, TADAO, additional, SATOMI, SUSUMU, additional, TAGUCHI, YOSHIO, additional, and MORI, SHOZO, additional

Published
1995
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38. SURVIVAL OF ACCOMMODATED CARDIAC XENOGRAFTS UPON RETRANSPLANTATION INTO CYCLOSPORINETREATED RECIPIENTS1,2

Author

Miyatake, Tsukasa, Koyamada, Nozomi, Hancock, Wayne W., Soares, Miguel P., and Bach, Fritz H.

Abstract

Accommodation designates the survival of vascularized grafts in the presence of circulating antigraft antibodies and complement. In the hamstertorat model, accommodation is associated with an ongoing T helperTh2 cytokine response and the expression of "protective genes" by the graft endothelial cells and smooth muscle cells. In this report, we tested whether accommodated xenografts would be protected from rejection upon retransplantation into second recipients treated with cyclosporine CsA, a treatment that does not prolong survival of a fresh hamster heart.

Published
1998

39. Isolated Pancreatic Metastasis From Renal Clear Cell Renal Cell Carcinoma 29 Years After Radical Nephrectomy.

Author

Fujiwara S, Koyamada N, Nishimura R, Miyazawa K, and Miyazaki S

Abstract

Isolated metastatic tumors of the pancreas from other origins are only 2-3% of pancreatic cancers, and renal cell carcinoma is the most common origin of metastasis. It is challenging to differentiate between pancreatic tumors and those with a history of renal cancer to optimize treatment and management of this tumor. Here, we present a case of isolated renal cell cancer metastasis to the pancreas, which occurred 29 years after the radical nephrectomy. Surgical resection and pancreatectomy is a feasible treatment because of the low rate of complication and favorable prognosis. However, isolated metastatic pancreatic cancer from renal cell cancer is rare and has relatively high risk of recurrence. Therefore, a larger sample size is necessary to evaluate long-term oncologic outcomes and to optimize diagnostic and therapeutic strategies., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2024, Fujiwara et al.)

Published
2024
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40. Giant hepatic metastasis from gastrointestinal stromal tumor of the rectum 12 years after surgery.

Author

Masuoka H, Kawagishi N, Inoue T, Ohkohchi N, Fujimori K, Koyamada N, Sekiguchi S, Tsukamoto S, and Satomi S

Subjects
Hepatectomy, Humans, Immunohistochemistry, Liver Neoplasms diagnostic imaging, Liver Neoplasms surgery, Magnetic Resonance Imaging, Male, Middle Aged, Prognosis, Rectal Neoplasms surgery, Tomography, X-Ray Computed, Liver Neoplasms secondary, Rectal Neoplasms pathology
Abstract

Gastrointestinal stromal tumors are non-epithelial neoplasms that arise from the gastrointestinal tract. Their variable cytologic atypia makes it difficult to predict their prognosis. We report a case of right hepatectomy for a giant metastasis detected 12 years after the surgical treatment of a rectal neoplasm, histologically demonstrated as a low-grade leiomyosarcoma initially, having morphological and immunohistochemical features of low malignancy. Histological examination of the hepatic metastases demonstrated that the tumors were composed of spindle cells similar to those in the rectal neoplasm. Immunohistochemical staining of the hepatic metastases with Ki-67 revealed stronger than the primary tumor. In conclusion, although histological and immunohistochemical analyses provide useful prognostic information, the prognosis of gastrointestinal stromal tumors is difficult to predict. Therefore, a patient with gastrointestinal stromal tumor diagnosed as low-grade malignancy requires carefully long-term follow-up.

Published
2003

41. [ABO-incompatible liver transplantation and patients with hepatopulmonary syndrome].

Author

Koyamada N and Satomi S

Subjects
Adolescent, Child, Child, Preschool, Female, Humans, Infant, Male, Perioperative Care, Survival Rate, ABO Blood-Group System, Blood Group Incompatibility, Hepatopulmonary Syndrome surgery, Liver Transplantation mortality, Liver Transplantation statistics & numerical data
Abstract

From 1991 to 2000, more than 100 ABO-incompatible liver transplantations were performed in 12 institution in Japan. The overall survival rate is 60%. Survival data appear to have improved in these years even in adult cases, although acute vascular rejection causing hepatic necrosis, infection, and intrahepatic bile duct injury are major complications to be resolved. Hepatopulmonary syndrome (HPS) was considered to be a contraindication to transplantation in the 1980s. However, even severe cases can recover from hypoxia after liver transplantation, and improved survival data were reported in the 1990s. Intensive respiratory therapy after transplantation with NO inhalation allows expansion of the indications for transplantation in HPS.

Published
2002

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