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285 results on '"Kouskouni, Evangelia"'

40. Genital tract infection and associated factors affect the reproductive outcome in fertile females and females undergoing in vitro fertilization

Author

Moragianni, Dimitra, primary, Dryllis, George, additional, Andromidas, Panagiotis, additional, Kapeta-Korkouli, Rachil, additional, Kouskouni, Evangelia, additional, Pessach, Ilias, additional, Papalexis, Petros, additional, Kodonaki, Antigoni, additional, Athanasiou, Nikolaos, additional, Pouliakis, Avraham, additional, and Baka, Stavroula, additional

Published
2019
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43. Increased Metabolic and Cardiorespiratory Stress with Isoenergetic Long vs. Short-Bout High-Intensity Interval Exercise

Author

Bogdanis, Gregory C., primary, Tsirigkakis, Spiros, additional, Katsoula, Alexandra, additional, Daskalaki, Georgia, additional, Chatzis, Alexandros, additional, Mantzou, Amalia, additional, Kouskouni, Evangelia, additional, Veligekas, Panagiotis, additional, Mougios, Vassilis, additional, and Mastorakos, George, additional

Published
2018
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44. Late Polypropylene Mesh Susceptibility to Infection during Intra-Abdominal Sepsis

Author

Ioannis, Vassiliou, Vassiliou, Ioannis, Aliki, Tympa, Tympa, Aliki, Theodosios, Theodosopoulos, Theodosopoulos, Theodosios, Constantinos, Nastos, Nastos, Constantinos, Nikolaos, Arkadopoulos, Arkadopoulos, Nikolaos, Nikolaos, Dafnios, Dafnios, Nikolaos, Georgios, Fragulidis, Fragulidis, Georgios, Evangelia, Kouskouni, Kouskouni, Evangelia, Vassilios, Smyrniotis, and Smyrniotis, Vassilios

Subjects
Male, medicine.medical_specialty, medicine.medical_treatment, Group ii, Escherichia coli O157, Polypropylenes, Gastroenterology, Postoperative Complications, Peritoneum, Sepsis, Internal medicine, Animals, Medicine, Rats, Wistar, Escherichia coli Infections, Herniorrhaphy, Interleukin-6, business.industry, Prostheses and Implants, Surgical Mesh, Hernia repair, Hernia, Abdominal, Rats, Surgery, Intra abdominal sepsis, Polypropylene mesh, C-Reactive Protein, medicine.anatomical_structure, business
Abstract

To evaluate the susceptibility of high-density polypropylene mesh to contamination, 1 year after experimental hernia repair.Wistar rats were randomized into two groups: one experimental group (n = 20) and another control group (n = 10). Mesh hernia repair was performed with intra-abdominal (group I, n = 10) or subcutaneous (group II, n = 10) implantation of grafts. The three groups were exposed to an intra-abdominal E. coli administration after 1 year of operation. After 24 hr, the meshes and peritoneum were sampled from the experimental and control groups, respectively, in order to assess bacterial inoculation. Immunoreaction to E. coli inoculation was also evaluated after 24 hr by measuring serum interleukin-6 (IL-6) and C-reactive protein (CRP) levels.Bacteriological analysis revealed increased contamination in groups I and II when compared with the control group (p = .001 and .007, respectively). IL-6 levels were increased in both groups I and II compared with the control group, 24 hr after E. coli injection (p = .034 and .022, respectively), while there was no statistically significant difference between groups concerning the concentration of CRP.Polypropylene mesh is vulnerable to bacterial inoculation during intra-abdominal sepsis 1 year after mesh placement.

Published
2011
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47. The role of microRNAs in the pathogenesis of endometrial cancer: a systematic review

Author

Sianou, Argiri Galyfos, George Moragianni, Dimitra and Andromidas, Panagiotis Kaparos, Georgios Baka, Stavroula and Kouskouni, Evangelia

Abstract

Epigenetics seem to play a primary role in the current research on the pathogenesis of different types of endometrial cancer. Data so far indicate that microRNAs regulate different pathways that could lead to carcinogenesis when not functioning properly. The aim of this review is to summarize current knowledge on microRNAs that have been associated with endometrial cancer development. From July 2014 to August 2014, we conducted a comprehensive research utilizing major online search engines (Pubmed, Crossref, Google Scholar). The main keywords used in our search were endometrial cancer/carcinoma; microRNA; epigenetics; novel biomarkers; pathogenesis. Overall, we identified 155 studies, although only 77 were eligible for this review. Different miRNAs were identified to contribute either promoting the carcinogenesis in the endometrium or inhibiting different steps of endometrial cancer development. Tumour growth, cell proliferation, apoptosis and invasion metastasis have been identified as the main processes where miRNAs seem to be implicated. microRNAs are effective regulators of gene expression that has a significant role in the pathogenesis of endometrial cancer. Research concerning possible therapeutic implications has been promising, although there is still a significant distance to be covered between research observations and clinical results. Extensive preclinical and translational research is still required to improve the efficacy and minimize unwanted effects of miRNAs-based therapy.

Published
2015

48. Greek-origin royal jelly improves the lipid profile of postmenopausal women

Author

Lambrinoudaki, Irene, primary, Augoulea, Areti, additional, Rizos, Demetrios, additional, Politi, Marianna, additional, Tsoltos, Nikolaos, additional, Moros, Michail, additional, Chinou, Ioanna, additional, Graikou, Konstantia, additional, Kouskouni, Evangelia, additional, Kambani, Susana, additional, Panoulis, Konstantinos, additional, and Moutsatsou, Paraskevi, additional

Published
2016
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49. Seroprevalence of HHV-6 and HHV-8 among blood donors in Greece

Author

Politou, Marianna Koutras, Dimitrios Kaparos, Georgios and Valsami, Serena Pittaras, Theodoros Logothetis, Emmanouil and Panayiotakopoulos, George Kouskouni, Evangelia

Subjects
viruses, virus diseases, biochemical phenomena, metabolism, and nutrition
Abstract

Background: Herpes viruses infection transmitted through healthy but infected blood donors pose a danger to herpes-naive immunocompromised recipients. The risk of transfusion-related HHV-8 transmission is different in endemic and not endemic areas. HHV-6 and HHV-8 seroprevalence and viral load among blood donors have been reported from different countries. The aim of our study was to assess the seroprevalence of HHV-8 and HHV-6 in volunteer blood donors from Greece which is unknown. Findings: Serum samples from 179 healthy blood donors were tested for the presence of IgG antibodies against HHV-6 and HHV-8 with ELISA. None of the 179 donors of Greek origin tested was positive for HHV-8. HHV-6 seropositivity was assessed in 160 blood donors’ samples and was found to be 78.75% ( 126/160). The HHV-6 seroprevalence did not differ either between males and females or among different decade age groups. Conclusions: The fact, that no blood donor was positive for HHV-8 IgG antibodies indicates that the risk for transfusion related HHV-8 transmission in Greece, if any, is negligible and does not warrant broad testing for HHV-8. Definitely further studies are needed, in order to clarify the potential risk of HHV-6 transmission.

Published
2014

50. Adropin levels in women with polycystic ovaries undergoing ovarian stimulation: correlation with lipoprotein lipid profiles.

Author

Bousmpoula, Artemis, Kouskouni, Evangelia, Benidis, Evangelos, Demeridou, Styliani, Kapeta-Kourkouli, Rachil, Chasiakou, Anthia, and Baka, Stavroula

Subjects
*DYSLIPIDEMIA, *POLYCYSTIC ovary syndrome, *OVARIAN physiology, *BODY mass index, *HUMAN in vitro fertilization
Abstract

This study aimed to investigate serum and follicular fluid (FF) adropin levels in polycystic ovary syndrome (PCOS) and normal women undergoing controlled ovarian stimulation and correlate them with the lipid and lipoprotein levels. We included 60 women (30 lean and 30 overweight) with diagnosed PCOS, and 60 age and weight-matched non-PCOS controls (30 lean and 30 overweight), under in vitro fertilization (IVF) treatment. Serum lipid and lipoprotein levels were assessed by the Abbott Architect c8000 autoanalyzer while adropin levels were determined by enzyme immunoassay. Serum and FF adropin levels were significantly lower in PCOS women compared with controls and FF adropin levels were lower than serum levels. Significantly higher serum levels of total cholesterol, LDL-C, triglycerides, apolipoprotein B, lipoprotein(a) and homocysteine were encountered in PCOS subjects, while HDL-C and apolipoprotein A1 were significantly lower compared with controls. According to univariate and multivariate analysis, serum and FF adropin levels were positively correlated with BMI and HDL-C levels and negatively correlated with LDL-C levels. Women with polycystic ovaries exhibit lipid lipoprotein alterations increasing the risk of cardiovascular diseases later in life. Our findings suggest a probable involvement of adropin both in human metabolism and in the pathophysiology of PCOS. [ABSTRACT FROM AUTHOR]

Published
2018
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