124 results on '"Kouri, G."'
Search Results
2. Validation du score visuel prostatique en images SVPI dans l’évaluation des symptômes du bas appareil urinaire associés à une hyperplasie bénigne de la prostate (550 patients)
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Descazeaud, A., Coloby, P., Davin, J.L., De La Taille, A., Karsenty, G., Kouri, G., Rossi, D., Pouteau, J.C., and Zerbib, M.
- Published
- 2017
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- View/download PDF
3. Enquête observationnelle, transversale de l’Association française d’urologie (AFU) sur la pratique du traitement hormonal intermittent dans le cancer de la prostate en France
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Salomon, L., Ploussard, G., Coloby, P., Kouri, G., Lebret, T., Méjean, A., Prunet, D., and Soulié, M.
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- 2014
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4. Évolution des symptômes du bas appareil urinaire sous silodosine : facteurs influençant la satisfaction des patients
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Descazeaud, A., Davin, J.-L., De La Taille, A., Karsenty, G., Kouri, G., Zerbib, M., Morris, V., Allaert, F.A., and Coloby, P.
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- 2014
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5. Troubles de l’humeur et cognitifs et suppression androgénique
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Frémont, P., Balardy, L., Faramarzi-Roques, D., Goldblatt, L., Kouri, G., Latorzeff, I., Mourey, L., Pasticier, G., Vavdin, F., and Rischmann, P.
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- 2012
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6. The action of the herbicide 2,4-dichlorophenoxyacetic acid on the isolated sciatic nerve of the frog (Rana Ridibunda)
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Kouri, G. and Theophilidis, G.
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- 2002
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7. Dengue, Dengue Hemorrhagic Fever
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Guzman, M.G., primary, Perez, A.B., additional, Fuentes, O., additional, and Kouri, G., additional
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- 2008
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8. Intersectoral coordination in Aedes aegypti control. A pilot project in Havana City, Cuba
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Sanchez, L., Perez, D., Pérez, T., Sosa, T., Cruz, G., Kouri, G., Boelaert, M., and Van der Stuyft, P.
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- 2005
9. Intérêt d’une évaluation systématique du traitement des symptômes du bas appareil urinaire dans la prise en charge d’une hypertrophie bénigne de la prostate en médecine générale
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Descazeaud, A., primary, Coloby, P., additional, Taille, A. De La, additional, Kouri, G., additional, Mallet, R., additional, Rossi, D., additional, Rozet, F., additional, Zerbib, M., additional, and Carrois, F., additional
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- 2018
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10. Community participation in Aedes aegypti control; a sociological perspective on five years of research in the health area '26 de Julio', Havana, Cuba
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Pérez, D., Lefèvre, P., Sánchez, L., Sánchez, L. M., Boelaert, M., Kouri, G., and Van der Stuyft, P.
- Subjects
Dengue ,Caribbean ,Aedes aegypti ,Sociology ,Community participation ,America, Latin ,Cuba ,Empowerment ,Viral diseases ,Vector control - Abstract
The definitive version is available at www3.interscience.wiley.com, OBJECTIVE: Effective dengue prevention and Aedes aegypti control is a priority for the Cuban health authorities. To enhance effectiveness, strategies oriented towards a more active involvement of communities in control activities are being tested. This paper presents a sociological perspective on a pilot project conducted in the health area ''26 de Julio'' (La Havana) in 1999-2004. METHODS: Instrumental case study based on an exhaustive content analysis of project documents and on observations of a sociologist. RESULTS: The context and the pilot project are systematically described and an analysis of the evolution of the underlying concept of community participation is provided. The pilot experience was a dynamic process influenced by self-reflection of the research team, feedback from research partners and changes in the epidemiological context (provoked by two dengue outbreaks during the study period). Community participation evolved from being just one component in Aedes aegypti control directed by the health staff into a learning and empowering process for the people. This change in the concept of participation was reflected in different aspects of the pilot project such as the learning and evaluation processes. CONCLUSION: Empirical evidence from 5 years of research in the particular context of Cuba showed that moves towards community-based Aedes aegypti control are feasible. However, in order to be successful, community-based dengue prevention should be a social learning process, implying a transfer of power and responsibilities to local people. Actions undertaken must be oriented towards creating local capabilities, strengthening existing structures and organizations and promoting group work for learning participation from participation itself.
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- 2007
11. Double trisomy (48,XXY,+21) in monozygotic twins: case report and review of the literature
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Iliopoulos, D Poultsides, G Peristeri, V Kouri, G and Andreou, A Voyiatzis, N
- Abstract
The occurrence of double aneuploidy in the same individual is a relatively rare phenomenon. We describe twin newborns with typical clinical features of Down’s syndrome, of which one revealed 48,XXY,+21 GTG-band karyotype. The second newborn died 2 days after its birth, and was clinically diagnosed having Down syndrome. Due to the same clinical features of the twins, the common placenta and amniotic sac, we speculate that they were monozygotics and as a result the second newborn should also be a Klinefelter. The purpose of this report is to present a rare case of possible coincidence of double aneuploidy in newborn twins. A review of the literature showed that double trisomy (48,XXY,+21) in a twin newborn infant has never occurred. (C) 2003 Elsevier SAS. All rights reserved.
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- 2004
12. Validation d’une échelle visuelle analogique (EVA) en médecine générale, dans l’évaluation des symptômes du bas appareil urinaire (SBAU) associés à une hypertrophie bénigne de la prostate (HBP)
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Coloby, P., primary, Davin, J.-L., additional, De la Taille, A., additional, Descazeaud, A., additional, Karsenty, G., additional, Kouri, G., additional, Rossi, D., additional, Jaquet, D., additional, and Zerbib, M., additional
- Published
- 2014
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- View/download PDF
13. Validation en médecine générale d’un score visuel prostatique en images (SVPI), dans l’évaluation des symptômes du bas appareil urinaire (SBAU) associés à une hypertrophie bénigne de la prostate (HBP)
- Author
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Descazeaud, A., primary, Coloby, P., additional, Davin, J.-L., additional, De la Taille, A., additional, Karsenty, G., additional, Kouri, G., additional, Rossi, D., additional, Jaquet, D., additional, and Zerbib, M., additional
- Published
- 2014
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14. Observatoire des patients présentant une hypertrophie bénigne de la prostate (HBP), traités par la silodosine : corrélations entre les symptômes urinaires, les troubles du sommeil et la qualité de vie des patients
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Coloby, P., primary, Davin, J.L., additional, De La Taille, A., additional, Descazeaud, A., additional, Karsenty, G., additional, Kouri, G., additional, Zerbib, M., additional, Morris, V., additional, and Allaert, F.A., additional
- Published
- 2013
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15. Enquête « PHARES » portant sur la pratique du traitement hormonal et du suivi transversal des patients traités pour cancer de la prostate en France : étude observationnelle, transversale réalisée chez des urologues membres de l’Association française d’urologie
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Salomon, L., primary, Coloby, P., additional, Kouri, G., additional, Lebret, T., additional, Méjean, A., additional, Prunet, D., additional, and Soulié, M., additional
- Published
- 2013
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- View/download PDF
16. Enquête « Horinf » portant sur la pratique du traitement hormonal intermittent dans le cancer de la prostate en France : étude observationnelle, transversale réalisée chez des urologues membres de l’association française d’urologie
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Salomon, L., primary, Coloby, P., additional, Kouri, G., additional, Lebret, T., additional, Méjean, A., additional, Prunet, D., additional, and Soulié, M., additional
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- 2012
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17. Role of the Cytokines and Chemokines in the Regulation of Innate Immunity in Dengue Virus Infection
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Sierra, B., primary, Perez, A.B., additional, Vogt, K., additional, García, G., additional, Schmolke, K., additional, Aguirre, E., additional, Alvarez, M., additional, Kouri, G., additional, Volk, H.D., additional, and Guzman, M.G., additional
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- 2008
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18. Epidemia de dengue en Nicaragua, 1985
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Kouri, G., Valdéz, M., Arguello, L., Guzmán, Maria G., Valdés, L., Soler, Maritza, and Bravo, J.
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Dengue hemorrágico - Abstract
In the second half of the year 1985, during the rainy season, an epidemic of Dengue Fever was recognized in Nicaragua. A total of 17.483 cases were reported by the health services. The highest morbidity and attack rates were reported between August and November of the same year. Regions II (Leon and Chinandega), III (Managua) and IV (Masaya, Granada, Carazo y Rivas) reported 89% of the cases; these regions are precisely the more densely populated in the country, located in the Pacific Coast. Leon and Chinandega were the more affected cities reporting 41% of the cases of the epidemic. Sixty seven percent of the cases were adults, 57% were female. The national attack rate was 55.4/10.000 inhab. An intensive campaign for the control of the vector was launched immediately after the epidemic was recognized and by the month of October 1985 morbidity decreased and an endemic situation was established. Seven fatal cases were reported in adults. They were considered as DHF/DSS cases by a multidisciplinary group of pathologists and clinicians, considering the criteria of WHO and the experience obtained during the cuban DHF/DSS epidemic, in 1981. The outbreak was considered as a Classical Dengue Fever epidemic with 7 fatalities. Dengue-1 and-2 were isolated from acute sera and Dengue-1 from one of the deads. En el segundo semestre de 1985, coincidiendo con el período de lluvias se produjo en Nicaragua una epidemia de Dengue en la que se reportaron 17,483 casos. La mayor morbilidad y las más elevadas tasas de ataque se registraron entre Agosto y Noviembre, siendo afectadas fundamentalmente las regiones II (León y Chinandega), III (Managua) y IV (Masaya, Granada, Carazo, Rivas) que acumularon el 89% de los reportes. Estas regiones se corresponden precisamente con las zonas más densamente pobladas ubicadas en la costa del Pacífico, en donde se encuentran los núcleos urbanos mas importantes y populosos del país. León y Chinandega fueron las ciudades mas afectadas, pues reportaron el 41% del total de casos registrados. El 66.8% de los casos eran adultos y el 57.6% del sexo femenino. La tasa global de ataque para el país fue de 55.24 x 10.000 habitantes. Una campaña de lucha antivectorial, fue iniciada de inmediato, manteniéndose en forma intensiva hasta el mes de Octubre. Al final de este período la morbilidad disminuyó considerablemente y la enfermedad entró en una fase de escasos reportes y posiblemente de endemia. Se reportaron 7 adultos fallecidos que fueron considerados como portadores de una FHD/SCD por un grupo mixto de patólogos y clínicos teniendo en cuenta la experiencia adquirida en los pacientes adultos durante la epidemia ocurrida en Cuba en 1981. El brote fue interpretado como una epidemia de Dengue Clásico en la cual se produjeron 7 casos fatales. Se aislaron los serotipos 1 y 2 del Dengue en sueros de fase aguda de pacientes y el serotipo 1 en el de uno de los fallecidos.
- Published
- 1991
19. Epidemic dengue in Nicaragua 1985
- Author
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Kouri, G., Valdéz, M., Arguello, L., Guzmán, Maria G., Valdés, L., Soler, Maritza, and Bravo, J.
- Subjects
Dengue hemorrágico - Abstract
En el segundo semestre de 1985, coincidiendo con el período de lluvias se produjo en Nicaragua una epidemia de Dengue en la que se reportaron 17,483 casos. La mayor morbilidad y las más elevadas tasas de ataque se registraron entre Agosto y Noviembre, siendo afectadas fundamentalmente las regiones II (León y Chinandega), III (Managua) y IV (Masaya, Granada, Carazo, Rivas) que acumularon el 89% de los reportes. Estas regiones se corresponden precisamente con las zonas más densamente pobladas ubicadas en la costa del Pacífico, en donde se encuentran los núcleos urbanos mas importantes y populosos del país. León y Chinandega fueron las ciudades mas afectadas, pues reportaron el 41% del total de casos registrados. El 66.8% de los casos eran adultos y el 57.6% del sexo femenino. La tasa global de ataque para el país fue de 55.24 x 10.000 habitantes. Una campaña de lucha antivectorial, fue iniciada de inmediato, manteniéndose en forma intensiva hasta el mes de Octubre. Al final de este período la morbilidad disminuyó considerablemente y la enfermedad entró en una fase de escasos reportes y posiblemente de endemia. Se reportaron 7 adultos fallecidos que fueron considerados como portadores de una FHD/SCD por un grupo mixto de patólogos y clínicos teniendo en cuenta la experiencia adquirida en los pacientes adultos durante la epidemia ocurrida en Cuba en 1981. El brote fue interpretado como una epidemia de Dengue Clásico en la cual se produjeron 7 casos fatales. Se aislaron los serotipos 1 y 2 del Dengue en sueros de fase aguda de pacientes y el serotipo 1 en el de uno de los fallecidos. In the second half of the year 1985, during the rainy season, an epidemic of Dengue Fever was recognized in Nicaragua. A total of 17.483 cases were reported by the health services. The highest morbidity and attack rates were reported between August and November of the same year. Regions II (Leon and Chinandega), III (Managua) and IV (Masaya, Granada, Carazo y Rivas) reported 89% of the cases; these regions are precisely the more densely populated in the country, located in the Pacific Coast. Leon and Chinandega were the more affected cities reporting 41% of the cases of the epidemic. Sixty seven percent of the cases were adults, 57% were female. The national attack rate was 55.4/10.000 inhab. An intensive campaign for the control of the vector was launched immediately after the epidemic was recognized and by the month of October 1985 morbidity decreased and an endemic situation was established. Seven fatal cases were reported in adults. They were considered as DHF/DSS cases by a multidisciplinary group of pathologists and clinicians, considering the criteria of WHO and the experience obtained during the cuban DHF/DSS epidemic, in 1981. The outbreak was considered as a Classical Dengue Fever epidemic with 7 fatalities. Dengue-1 and-2 were isolated from acute sera and Dengue-1 from one of the deads.
- Published
- 1991
20. Dengue virus type 2 in Cuba, 1997: conservation of E gene sequence in isolates obtained at different times during the epidemic
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Rodriguez-Roche, R., primary, Alvarez, M., additional, Gritsun, T., additional, Rosario, D., additional, Halstead, S., additional, Kouri, G., additional, Gould, E. A., additional, and Guzman, M. G., additional
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- 2004
- Full Text
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21. Detection and genetic relationship of dengue virus sequences in seventeen-year-old paraffin-embedded samples from Cuba.
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Sariol, C A, primary, Kouri, G, additional, Arteaga, E, additional, Guzman, M G, additional, Pelegrino, J L, additional, and Martinez, A, additional
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- 1999
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22. [NO TITLE AVAILABLE]
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Kouri, G., primary, Valdéz, M., additional, Arguello, L., additional, Guzmán, Maria G., additional, Valdés, L., additional, Soler, Maritza, additional, and Bravo, J., additional
- Published
- 1991
- Full Text
- View/download PDF
23. Dengue virus type 2 in Cuba, 1997: conservation of E gene sequence in isolates obtained at different times during the epidemic.
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Rodriguez-Roche, R., Alvarez, M., Gritsun, T., Rosario, D., Halstead, S., Kouri, G., Gould, E. A., and Guzman, M. G.
- Subjects
DENGUE viruses ,EPIDEMICS ,GENES ,PHYLOGENY - Abstract
It was recently reported that disease severity increased during the 1997 Cuban dengue 2 virus epidemic and it was suggested that this might be explained by the appearance of neutralization resistant escape mutants. We investigated these observations and ideas by sequencing 20 dengue 2 virus isolates obtained during the early (low case fatality rate) and the late (high case fatality rate) phases of the outbreak. Our results showed total conservation of the E gene sequence for these isolates suggesting that the selection of envelope gene escape mutants was not the determinant of increased disease severity. Alignment of these sequences with those available in GenBank, followed by Maximum likelihood phylogenetic analysis generated a tree, which indicated that our isolates are closely related to the virus that circulated in Venezuela in 1997/98 and subsequently in Martinique in 1998. This “American/Asian” genotype has therefore gradually dispersed across the Caribbean region during the past 5 years. [ABSTRACT FROM AUTHOR]
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- 2005
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24. Society, economy, inequities and dengue | Sociedad, economía, inequidades y dengue
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Kouri, G., José Luis Pelegrino Martínez de la Cotera, Munster, B. M., and Guzmán, M. G.
25. Data elements of men considering individual screening of prostate cancer. Occupational recommendations - Economic evaluation. September 2004: Document for the use of health professionals,Éléments d'information des hommes envisageant la réalisation d'un dépistage individuel du cancer de la prostate. Recommandations professionnelles - Évaluation économique. Septembre 2004: Document à l'usage des professionnels de santé
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Ancelle-Park, R., Assicot, M., Claveirole, P., Coloby, P., Doublet, J. -D, Bels, F., Dosquet, P., Maisonneuve, P., May-Levin, F., Rumeau-Pichon, C., Shojaei-Brosseau, T., Poullié, A. -I, Fortanier, C., Clavel, J. -P, Cornud, F., Delattre-Massy, H., Drahi, É, Eddi, A., Filloux, Y., Fulla, Y., Maidenberg, M., Moreau, F., Moreau, J. -L, Oriol, J. -M, Richaud, P., Roy, C., Soulie, M., Thelliez, P., Theodore, C., Vincent, I., Aguirre Junco, A. R., Aquino, J. -P, Atlan, P., Bey, P., Bolla, M., Bouchacourt, P., Brune, D., Carpuat, C., Carrere, M. -O, Carrie, C., Clerc, P., Cosset, J. -M, Coulange, C., Cressely, P., Cuzin, B., Dana, A., Delcey, M., Demeaux, J. -L, Duport, N., Feingold, J., Fontaine, É, Fourcade, R., Gavid, B., Grosclaude, P., Haillot, O., Hedelin, G., Hélénon, O., Hennequin, C., Hill, C., Irani, J., Jean, T., Joffre, F., Jonquille, C., Kouri, G., Labib, A., Laguens, J. -P, Landais, P., Lartigau, É, Launoy, G., Legrain, S., Lehnisch, R., Lesaunier, F., Levesque, J. -L, Mahe, M. -A, Menegoz, F., Mignot, L., Minne, J. -F, Molinié, V., Mouillefarine, P., Moumjid, N., Paget, J. -M, Paturel, J. -L, Rebillard, X., Richard, F., Rousselot, F., Sancho-Garnier, H., Sautron, J. -B, Schouman-Claeys, É, Serain, F., Stoppa-Lyonnet, D., Touboul, E., Yvan Touitou, Truc, G., Vernet, B., and Villers, A.
26. 40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004
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Veitenhansl, M., Stegner, K., Hierl, F-X, Dieterle, C., Feldmeier, H., Gutt, B., Landgraf, R., Garrow, A. P., Vileikyte, L., Findlow, A., Waterman, C., Boulton, A. J. M., Shankhdhar, K., Shankhdhar, L., Shankhdhar, U., Petrova, N. L., Foster, A. V. M., Edmonds, M. E., Ferraresi, R., Caravaggi, C., Giglio, R., Cavaiani, P., Pogliaghi, I., Sommariva, E., Katz, I. A., Harlan, A., Miranda-Palma, B., Prieto-Sanchez, L., Armstrong, D. G., Bowker, J. H., Mizel, M. S., Cernea, S., Wohlgelernter, J., Kidron, M., Modi, P., Raz, I., Arbit, E., Nosek, L., Kapitza, C., Beckett, P., Gelfand, R., Goldberg, M., Heise, T., Testa, M. A., Turner, R. R., Hayes, J. F., Scranton, R. E., Simonson, D. C., Yang, Y-W, Hsu, Y-J, Naujok, O., Francini, F., Jorns, A., Tiedge, M., Lenzen, S., Abdel-Wahab, Y. H. A., Marenah, L., Orr, D. F., Shaw, C., Flatt, P. R., Chokkalingam, K., Mansell, P. I., Clausen, P., Ekbom, P., Damm, P., Feldt-Rasmussen, U., Nielsen, B., Mathiesen, E. R., Feldt-Rasmussen, B., Dewan, S., Da Silva, N., Ternan, P. Mc, Leong, K. S., Wilding, J. P. H., Asatiani, N., Kurashvili, R., Dundua, M., Shelestova, E., Pagava, K., Ramazashvili, M., Hod, M., Smirnov, S., Petersen, J. L. A., Justesen, T. I., Ringholm Nielsen, L., Muller, C., Hojlund, K., Wensaas, A., Kase, E. T., Aas, V., Rustan, A. C., Thoresen, G. H., Levin, K., Beck-Nielsen, H., Gaster, M., Im, S-S, Kang, S-Y, Kim, S-Y, Ahn, Y-H, Lihn, A. S., Schmoll, D., Werner, T., Kienitz, A., Meyer, M., Barthel, A., Ailett, F., Sutherland, C., Walther, R., Grempler, R., Sasson, S., Reich, R., Tenenbaum, T., Alpert, E., Anfossi, G., Russo, I., Traversa, M., Massucco, P., Mattiello, L., Doronzo, G., Trovati, M., Lally, S., Tan, C. Y., Owens, D., Tomkin, G. H., Porchay, I., Pean, F., Bellili, N., Betoulle, D., Balkau, B., Tichet, J., Marre, M., Fumeron, F., Group D.E.S.I.R., Chatellier, G., Alhenc-Gelas, F., Diabhycar, Study Group, Nichols, G. A., Brown, J. B., Hayes, R. P., Bowman, L., Drexel, H., Saely, C. H., Marte, T., Benzer, W., Langer, P., Hoefle, G., Moll, W., Aczel, S., Karagiannis, E., Lubben, G., Urquhart, R., Edwards, G., Bruce, S., Howlett, H. S. C., Cugnardey, N., Turner, K. C., Park, J-S, Fiedorek, F. T., Avogaro, A., Gallo, A., Pinton, P., Rizzuto, R., Murphy, E., Ceolotto, G., Caterson, I., Guy-Grand, B., Hill, J., Barone, M., Aiello, A., Allochis, G., Borzi, V., Cannata, F., Caronna, S., D Avanzo, A., Elli, R., Formoso, G., Paroli, A., Scardapane, R., Sorichetti, P., Tatti, P., Viviani, G., Santeusanio, F., Italian Repaglinide Study Group, Manzella, D., Grella, R., Abbatecola, A. M., Paolisso, G., Sondergaard, L. G., Monster, T. B. M., Johnsen, S. P., Olsen, M. L., Mclaughlin, J. K., Sorensen, H. T., Lervang, H. H., Rungby, J., Lyssenko, V., Fredriksson, J., Almgren, P., Anevski, D., Orho-Melander, M., Sjogren, M., Tuomi, T., Groop, L., Jaziri, R., Aubert, R., Tuomilehto, J., Hu, G., Jousilahti, P., Peltonen, M., Lindstrom, J., Laina, A., Alevizaki, M., Philippou, G., Souvatzoglou, A., Anastasiou, E., Alba, S., Metcalf, B. S., Voss, L. D., Jeffery, A. N., Wilkin, T. J., Gluimer, C., Colagiuri, S., Vistisen, D., Borch-Johnsen, K., Haynes, A., Bower, C., Bulsara, M. K., Jones, T. W., Davis, E. A., Mortensen, H. B., Hougaard, P., Holl, R., Swift, P., Pociot, F., Knip, M., Hansen, L., Szadkowska, A., Pietrzak, I., Zmyslowska, A., Wyka, K., Bodalski, J., Holl, R. W., Swift, R., Hougaard, R., Gerstl, E-M, Engelsberger, I., Rabl, W., Rosenbauer, J., Grobe, H., Hofer, S. E., Krause, U., DPV-Wiss-Study Group, Dabelea, D., Morgan, T., Pettitt, D. J., Dolan, L., Mayer-Davis, E. J., Pihoker, C., Hillier, T. A., Imperatore, G., Ruggiero, A., Hamman, R. E., Stylianou, A., Tentolouris, N., Perrea, D., Tselepis, A. D., Lourida, E., Kitsou, E., Katsilambros, N., Vedovato, M., Dodesini, A. R., Lepore, G., Tiengo, A., Trevisan, R., Penno, G., Miccoli, R., Pucci, L., Lucchesi, D., Bandinelli, S., Fotino, C., Triscornia, S., Baldassari, E., Del Prato, S., Reboldi, P., Santeusanio, E., Fuller, J., Langham, R. G., Gow, R. M., Zhang, Y., Kelly, D. J., Christensen, P. K., Parving, H-H, Gilbert, R. E., Chibalin, A. V., Zhong, Z., Kotova, O., Davidescu, A., Ehren, I., Ekberg, K., Wahren, J., Wassef, L., Buckley, A. J., Rooney, K. B., Briody, J., Thompson, M., Ozanne, S. E., Thompson, C. H., Chamson-Reig, A., Summers, K., Arany, E. J. R., Hill, D. J., Solerte, S. B., Gazzaruso, C., Locatelli, E., Precerutti, S., Schifino, N., Ferrari, E., Fioravanti, M., Phenekos, C. V., Ginis, A., Fragaki, I., Chalkiadaki, M., Tzioras, C., Powell, L. A., Mcguire, G. M., Jewhurst, V., Trimble, E. R., Rasmussen, B. 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L., Hopkins, D., Anand, V., Lim, E., Raval, U., Sharp, P., Corder, R., Lipkin, D., Lahiri, A., Bartnik, M., Ryden, L., Ferrari, R., Malmberg, K., Pyorala, K., Simoons, M. L., Standl, E., Soler-Soler, J., Ohrvik, J., Euro Heart Survey Investigators, Bruce, D. G., Starkstein, S. E., Schauer, U. J. W., Astrup, A. S., Pietraszek, L., Nielsen, F. S., Rossing, P., Ali, S., Smidt, U. M., Yokoyama, H., Pavkov, M. E., Knowler, W. C., Bennett, P. H., Nelson, R. G., Lopez-Alba, A., Morcillo, L., Caballero, A., Montoya, L., Jimenez, A., Maceira, B., Lewis, J. B., Ravid, M., Wajman, A., Tadgell, C., Remuzzi, G., Hunsicker, L. G., Wessman, M., Taskinen, M-R, FinnDiane Study Group, Pugliese, G., Amadio, L., Menini, S., Oddi, G., Ricci, C., Iacobini, C., Pricci, F., Sorcini, M., Pesce, C., Migliaccio, E., Giorgio, M., Pelicci, P., Di Mario, U., Lassila, M., Jandeleit-Dahm, K., Seah, K. K., Calkin, A. C., Allen, T. J., Cooper, M. E., Lopes Faria, J. M., Cavakcanti, T. C., Silva, K. C., Ferrari, A. 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27. ANTIBODY-DEPENDENT ENHANCEMENT OF DENGUE 2 VIRUS IN PEOPLE OF WHITE DESCENT IN CUBA
- Author
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Morier, L., primary, Kouri, G., additional, Guzman, G., additional, and Soler, M., additional
- Published
- 1987
- Full Text
- View/download PDF
28. A Study of Microfoci and Inclusion Bodies produced by Rubella Virus in the RK-13 Cell Line
- Author
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Kouri, G., primary, Aguilera, A., additional, Rodriguez, P., additional, and Korolev, M., additional
- Published
- 1974
- Full Text
- View/download PDF
29. Dengue: where are we today?
- Author
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Guzman MG, Vazquez S, and Kouri G
- Abstract
Dengue is considered the main arthropod-borne viral disease of humans. In the last few years, an increasing number of reports of mild and severe cases have been reported. The growing dengue incidence observed in recent years has been accompanied by reports of new observations, findings and global initiatives with an improvement in our understanding of this phenomenon. The epidemiology and new clinical classification of dengue, advances in the diagnostic and pathogenesis knowledge, and vaccine development as well as control methods including new global initiatives are summarised here. [ABSTRACT FROM AUTHOR]
- Published
- 2009
30. 427-PA12 AIDS and tuberculosis in the Republic of Cuba
- Author
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González, E., Pérez, J., Díaz, M., Valdivia, J., Armas, L., and Kourí, G.
- Published
- 1995
- Full Text
- View/download PDF
31. 40(th) EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004
- Author
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S. Artigas, A V Dreval, Mark I. McCarthy, C Watson, Peter H. Bennett, M Quint, Y Ikeda, E Alpert, F Schiele, H Sekihara, Erik Gylfe, P Lowe, J Kuhlmann, Alain Golay, V Longo, Shahidul Alam Khan Akm., L G Mantovani, M Zawodniak-Szalapska, G Winkler, T Harrity, L Virág, U Johne, Kuo S-W., Linda C Tapsell, J Rodriguez, Michel Komajda, K Kankova, Carole A. Cull, M Sporna, E Estilles, U Ribel, M C Spruce, E Buzzigoli, T Prazak, J K McLaughlin, M K Lingohr, M Lim, F Calara, A Siebenhofer, G Meregalli, Roberto Anichini, A D Baron, R Kurashvili, P C Butler, G I Fantus, T. E. De Gooyer, Park Y-M., R. Walther, S Heinrich, Agnieszka Zawiejska, S Mukherjee, Nikolaos Papanas, G Wong, Ian D. Caterson, David M. Maahs, Shuichi Kaneko, Alexandra E. Butler, Francisco Javier Ampudia-Blasco, O N Kong, Attali J-R., C A Hedman, K Oshinyemi, Nicolle Müller, I C Cranston, N Okumus, M V Vlaiculescu, Balasubramanian Ravikumar, W W Cheatham, K Mukasa, K B Biswas, Annunziata Lapolla, Phil McEwan, G Mader, Gilles Chassot, Dragi Anevski, Werner A. Scherbaum, M Donath, C Hesselmann, R A Gandhi, David E. Moller, Ezio Bonifacio, C Garcia, V Ifandi, P Hornnes, Nieuwenhoven Fav., C Puech, S Pérez-Del-Pulgar, Kim S-R., G Hines, C Rubio Terrés, Michael Gaster, N. Hosszufalusi, A Scholze, Andrew A. Young, Stavros Liatis, F Hariri, S Tan, Paul Valensi, Allan E. Karlsen, J Kim, E. Moberg, J Kaiser, L Berman, G Nelson, A Altkrüger, P Kothare, D B Cook, S Doran, G. van Dijk, Shahnaz Shahinfar, Kim C-S., P Stahl, M Manousaki, S Sigrist, S K Lim, M. P. Stern, A Guberti, C Rezzani, J McKenney, Karl Thomaseth, Sofia Carlsson, M Julia, R Brillante, I Rubesova, T Darkow, E Matsumoto, Wendy M. 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Halban, Daniel J. Cox, O Ljungkvist, Justine Davies, J Palsgaard, Lars Sjöström, E Bosi, L Janin-Manificat, W. F. Kelly, M. Fernandez, E Colak, O V Mulyarchik, B Kronshage, F Lang, M Erfurth, Takashi Kadowaki, N Jendrike, U Walter, J Wishart, Y. Neye, D Kim, N Furuhashi, M Barsotti, D Florow, L Ke, L Borgquist, N C Jackson, Ffolliott M. Fisher, V Baskar, K Yoshioka, Bryan A. Wolf, G Chabrier, R Skoumal, Livio Luzi, H Kose, I Pharisien, B. Klein, H Winiarska, M C Johnson, L Griffiths, Nonna Kravchun, C Combe, Baptist Gallwitz, J Zdychova, L Skorda, Jorma Ilonen, W Gao, I N Steen, A Terrinoni, P D Ambery, W Kern, C M Kusminski, Cho M-H., Paolo Pozzilli, Louise G. Grunnet, E Schönle, David R Matthews, Robert W. Taylor, Y Cohen, Kim H-S., M P Eccles, N B Tutuncu, D McDowell, Richard M. Bergenstal, K Takamatsu, T Steiner, Jaan Palgi, Valdemar Grill, N Niculescu, G Federici, S Lehto, P. M. McKeigue, M Barone, Michael E. 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Chauveau, P, Combe, C, Baillet blanco, L, Beauvieux, M, Gin, H, Heinrich, S, Steiner, T, Ott, U, Holdass, H, Fellström, B, Jardine, A, Staffler, B, Logan, J, Gimpelewicz, C, Stanciu, C, Pena, C, Serafinceanu, C, González posada, J, Hernández, D, Pérez tamajó, L, Ló, A, Herná Alarcó, M, Meneses, M, Barsotti, M, Rizzo, G, Schmauss, S, Havrdova, T, Saudek, F, Boucek, P, Adamec, M, Invitti, C, Gilardini, L, Parati, G, Mazzilli, G, Pontiggia, B, Sartorio, A, Lutgers, H, Groenier, K, Zasadzinska, G, Saryusz wolska, M, Kurktschiev, D, Majdrakova, I, Varbanova, T, Todorova, B, Bajo martinez, A, Bernal, E, Sanchez, O, Ugalde canitrot, A, Sanchez largo, E, Coca robinot, D, Fabregate, R, Calbacho, M, Marquez, J, Saban ruiz, J, Penesova, A, Cizmarova, E, Blazicek, P, De Jongh, R, Serné, E, Ijzerman, R, De Vries, G, Andersen, N, Knudsen, S, Helleberg, K, Mogensen, C, Waluś, M, Idzior waluś, B, Sztefko, K, Cieślik, G, Fedak, D, Wozniakiewicz, E, Lin, S, Guo, M, Lin, C, Liu, X, Francisco, M, Rodriguez rosas, H, Peiró martinez, I, Macías batista, A, Harte, A, Rodriguez cuenca, S, Valsamakis, G, Chetty, R, Anderson, L, Roca, P, Matyka, K, Lasalle, J, Hershon, K, Berman, L, Gibson, E, Gillen, D, Maroni, J, Simmons, D, Hiukka, A, Forder, P, Leinonen, E, Hilden, H, Fruchart, J, Keech, A, Farnier, M, Freeman, M, Macdonell, G, Perevozskaya, I, Mitchel, Y, Gumbiner, B, Didangelos, T, Athyros, V, Mikhailidis, D, Papageorgiou, A, Bouloukos, V, Pehlivanidis, A, Symeonidis, A, Elisaf, M, Mckenney, J, Insull, W, Lewin, A, Maccubbin, D, Kush, D, Schuster, H, Barter, P, Stender, S, Bonnet, J, Morrell, J, Watkins, C, Kallend, D, Stalenhoef, A, Ballantyne, C, Murin, J, Tonstad, S, Rose, H, Wilpshaar, W, Jenkins, A, Karschimkus, C, Dragicevic, G, Rowley, K, Wolthers, T, Best, J, Voet, B, Murdoch, S, Marcovina, S, Brunzell, J, Caparevic, Z, Kostic, N, Ilic, S, Sartore, G, Piarulli, F, Cantaro, S, Reitano, R, Fiore, C, Marin, R, Bassan, S, Manzato, E, Fedele, D, Solini, A, Santini, E, Thornalley, P, Babaei jadidi, R, Karachalias, N, Kupich, C, Ahmed, N, Fowler, A, Baker, A, Starczynski, J, O'Hare, P, Szepietowska, B, Szelachowska, M, Puch, U, Glebocka, A, Quinn, D, Mcternan, C, Bonser, R, Idzior walus, B, Woźniakiewicz, E, Dimitriou, K, Apostolou, O, Kontela, E, Devangelio, E, Gould, E, Serri, O, Roussin, A, Buithieu, J, Mamputu, J, Renier, G, Giordanetti, S, De Amici, E, Poggi, G, Turpini, C, Fratino, P, Garzaniti, A, Banu, I, Paries, J, Roman, G, Negrean, M, Bala, C, Nita, C, Kistorp, C, Gustafsson, F, Chong, A, Lip, G, Galatius, S, Ari, N, Sahilli, M, Ceylan isık, A, Ozansoy, G, Karasu yilmaz, C, Matteucci, E, Rosada, J, Pallini, M, Evangelista, I, Cassetti, G, Giusti, C, Giampietro, O, Capaldo, B, Galderisi, M, Cicala, S, Turco, A, Imbroinise, A, Nosso, G, D'Errico, A, De Divitiis, O, Klimontov, V, Korolyova, E, Jeltova, L, Bondar, I, Tarkun, I, Arslan, B, Canturk, Z, Tarkun, P, Agacdiken, A, Komsuoglu, B, Méneveau, N, Pierre justin, E, Alsayed, M, Sabbah, R, Paulin, S, Marcu, S, Tauveron, I, Zimmermann, C, Schiele, F, Seronde, M, Vautrin, P, Lusson, J, Thieblot, P, Bernard, Y, Mistry, A, Pye, M, Peovska, I, Maksimovic Pavlovic, J, Vavlukis, M, Pop Gorceva, D, Bosevski, M, Scognamiglio, R, Negut, C, De Kreutzenberg, S, Madonna, R, De Caterina, R, Willerson, J, Geng, Y, Vahsen, S, Ledwig, D, Ramrath, S, Frantz, S, Schmidt, I, Calvillo, L, Dienesch, C, Elbing, I, Bischoff, H, Ertl, G, Bauersachs, J, Davydov, A, Mkrtum'Yan, A, Baranova, L, Ikeda, Y, Suehiro, T, Osaki, F, Ota, K, Arii, K, Kumon, Y, Hashimoto, K, Doney, A, Morris, A, Palmer, C, Byun, S, Doo, H, Pagnin, E, Calo, L, Fadini, G, Kubaszek, A, Chai, S, Chai, Q, Rasmussen, L, Ledet, T, Wogensen, L, Lengyel, C, Varró, A, Virág, L, Magyar, J, Bíró, T, Jost, N, Skoumal, R, Nánási, P, Tóth, M, Horkay, F, Papp, J, Zacharopoulou, O, Athanaselis, S, Tsokos, N, Doupis, J, Psallas, M, Cokkinos, D, Pavlatos, S, Liatis, S, Akhobadze, T, Dzneladze, L, Samarguliani, I, Taskiran, M, Rasmussen, V, Jensen, G, Fisher, A, Petrovsky, N, Srikusalanukul, W, Budge, M, Trifunovic zamaklar, D, Zivkovic, M, Jelic, V, Vukomanovic, G, Ristic, A, Seferovic, P, Costa, J, Duarte, S, Manley, S, Sailesh, S, Venkataraman, A, Haider, Y, Groza, I, Oprean, M, Ardelean, A, Morosanu, A, Darkow, T, Vanderplas, A, Mamas, M, Mcelduff, P, Burns, J, Edwards, R, Fitchet, A, Young, R, Gibson, J, Lichiardopol, R, Niculescu, N, Totora, A, Pencea, C, Tomescu, I, Cinteza, M, Manicardi, V, Coscelli, C, Navazio, A, Catellani, E, Michelini, M, Dall'Asta, D, Guberti, A, Piazza, A, Gasparini, E, Pantaleoni, M, Guiducci, U, Manari, A, Sejil, S, Janand delenne, B, Avierinos, J, Habib, G, Labastie, N, Vague, P, Lassmann vague, V, Luźniak, P, Tatoń, J, Wojciechowska Luźniak, A, Zairis, M, Lyras, A, Patsourakos, N, Tsirimbis, V, Foussas, S, Lupón, J, Urrutia, A, Herreros, J, González, B, Coll, R, Altimir, S, Prats, M, Valle, V, Abreu padí, C, Rábago, G, Ivanova, L, Brasacchio, D, Harno, E, Keenan, A, Li, H, Lu, Z, Ke, L, Liu, H, Jeong, I, Chae, M, Choi, M, Yoo, H, Kim, C, Yun, M, Na, M, Kang, Y, Kong, O, Son, S, Kim, I, Tanaka, N, Hosoi, M, Matsuyama, Y, Fukumoto, M, Yamakita, T, Yoshioka, K, Ishii, T, Sato, T, Fujii, S, Aoki, T, Shibata, T, Mizutani, N, Suzuki, J, Fowelin, J, Samuelsson, P, Brandrup wogsen, G, Okumura, K, Tokmakova, A, Staroverova, D, Antcieferov, M, Shutichina, I, Kuntchevich, G, Vriesendorp, T, Morélis, Q, Legemate, D, Schaper, F, Mainas, E, Gkioulmpasanis, I, Panagiotou, I, Vassilikos, G, Skorda, L, Sidira, M, Christoforidou, M, Alaveras, A, Artikis, V, Evdemon, E, Lechleitner, M, Koch, T, Ebenbichler, C, Sturm, W, Moretti, L, Moruzzo, D, Boldrini, E, Pandolfo, C, Kameyama, M, Iwasa, R, Cho, M, Nam, J, Huh, K, Kaplar, M, Paragh, G, Erdei, A, Csongradi, E, Garai, I, Varga, J, Galuska, L, Udvardy, M, Higa, M, Kaneko, Y, Hiroi, N, Koziarska, D, Nowacki, P, Majkowska, L, Luzniak, P, Wojciechowska luźniak, A, Tushuizen, M, Nieuwland, R, Snoeck, D, Sturk, A, Diamant, M, Aguiar, L, Bahia, L, Villela, N, Laflor, C, Conde, C, Bottino, D, Dorigo, D, Bouskela, E, Pu, S, Luo, Z, Lam, K, Dan, Q, Xu, A, Shen, J, Cheng, K, Xu, J, Thamer, C, Stefan, N, Haap, M, Heller, E, Tschritter, O, De Prado, A, Ortiz, A, Ybarra, J, Gich, I, Pou, J, Ehren, M, Roggenland, D, Reinsen, B, Klein, H, Rittig, K, Stock, J, Kocher, B, Balletshofer, B, Shon, H, Chung, D, Nakatani, Y, Matsuhisa, M, Kaneto, H, Hatazaki, M, Yoshiuchi, K, Katakami, N, Kawamori, D, Ohtoshi, K, Sakamoto, K, Matsuoka, T, Ozawa, K, Ogawa, S, Hori, M, Yamasaki, Y, Zitouni, K, Harry, D, Nourooz zadeh, J, Earle, K, Olesen, P, Franco, L, Corvaja, C, Semplicini, A, Ceylan işık, A, Arı, N, Rösen, P, Lee, I, Park, K, Jung, E, Shin, D, Jo, S, Obuobie, K, Prakash, P, Hanna, F, Lazarus, J, Varadhan, L, Gurushankar, J, James, D, Sheikh, S, Gaede, P, Zou, D, Vilarrasa, N, Perez maraver, M, Mena, E, Perez, D, Setti, G, Buckingham, R, Urbančič, V, Stefanovska, A, Bernjak, A, Ažman juvan, K, Kocijančič, A, Glowania, A, Filters, T, Fosmark, D, Torjesen, P, Kilhovd, B, Berg, T, Sandvik, L, Hanssen, K, Mentink, C, Donchenko, G, Stepanenko, S, Maingrette, F, Deng, H, Lindenmair, A, Freudenthaler, A, Baumgartner parzer, S, Nizheradze, K, Khoruzhenko, A, Tronko, N, Sheu, W, Ou, H, Shen, H, Lin, T, Wu, H, Yang, C, Mogylnytska, L, Schmoelzer, I, Davies, J, Band, M, Struthers, A, Prázný, M, Škrha, J, Kasalová, Z, Neelotpol, S, Jahan, P, Kauschke, S, Harrop, C, Schäfer, A, Widder, J, Eigenthaler, M, Walter, U, Uchimura, I, Ikebukuro, M, Kaibara, M, Hirata, M, Helal, R, Pervin, F, Yang, X, Jansson, P, Nagaev, I, Jack, M, Carvalho, E, Sunnerhagen, K, Cam, M, Cushman, S, Smith, U, Creely, S, Farmer, J, Gustafson, B, Kusminski, C, Krusinova, E, Wohl, P, Klementova, M, Lanska, V, Mcdougall, C, Kelly, I, Abbas, Z, Lutale, J, Archibald, L, Karunajeewa, H, Stingemore, N, Stuccio, G, Mcgechie, D, Muller, L, Hak, E, Goudzwaard, W, Montorsi, F, Homering, M, Sprenger, K, Goldstein, I, Asnaghi, V, Ferrari, G, Rastaldi, M, Gabellini, D, Dell'Antonio, G, Maestroni, A, Ruggieri, D, Luzi, L, Piemonti, L, Zerbini, G, Anafaroglu, I, Tutuncu, N, Sultana, M, Siddiqua, N, Iwasaki, T, Nakajima, A, Yoneda, M, Mukasa, K, Tanaka, S, and Sekihara, H
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0303 health sciences ,medicine.medical_specialty ,business.industry ,EASD ,Endocrinology, Diabetes and Metabolism ,Human physiology ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,Diabetes mellitus ,Family medicine ,Internal Medicine ,Medicine ,business ,030217 neurology & neurosurgery ,030304 developmental biology - Published
- 2004
32. Rejection in romantic relationships: Does rejection sensitivity modulate emotional responses to perceptions of negative interactions?
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Richter M, Kouri G, Meuwly N, and Schoebi D
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- Humans, Male, Female, Adult, Young Adult, Social Perception, Rejection, Psychology, Emotions, Interpersonal Relations, Sexual Partners psychology
- Abstract
Background: Rejection is a highly stressful experience and individuals tend to avoid it whenever possible. In intimate relationships, experiences of rejection can shape the interaction dynamics between partners. Highly rejection sensitive people fear that their romantic partner will reject them and they overreact to any ambiguous cues that might indicate rejection. Furthermore, because they focus on the threat of rejection, they may have difficulty disengaging from rejection-related emotions, persevere in a rejection-focused state and have a reduced capacity to regulate their emotions. The prolonged experience of strong negative emotions, together with maladaptive attempts to respond to rejection, may undermine key relationship maintenance processes that contribute to relationship functioning and lead to negative reciprocity in interactions. The goal of the present study was to shed light on how individuals experience rejection-related emotions and determine whether, following perceptions of negative interactions, rejection sensitivity was associated with stronger negative responses and less efficient downregulation of negative emotions. In addition, we examined whether dyadic patterns of rejection sensitivity were associated with negative emotion dynamics following perceptions of negative interactions., Methods: The participants (N = 298) were couples experiencing the transition to parenthood. A multilevel modelling approach was used to assess the associations between rejection sensitivity, perceptions of negative interactions and emotional states. The analyses included repeated daily reports for both rejection and emotions., Results: The results suggest that rejection sensitive individuals do not report higher negative emotions when they perceive negative interactions. Moreover, rejection sensitive men and women did not remain longer in a negative emotional state after they perceived negative interactions with their partner. Finally, when both men and women partners reported higher levels of rejection sensitivity, neither reported having higher negative emotions after experiencing negative interaction perceptions., Conclusions: Our findings provide further insights into emotional dynamics and rejection sensitivity in romantic relationships. Our results do not provide evidence for a link between rejection sensitivity and higher negative emotions or slower recovery after reports of negative interactions. If individuals suppress their emotions, they may not benefit from regulation with their partner and instead may protect themselves over their relationships. However, in this context, rejection sensitivity might also not constitute a strong predictor of daily emotion fluctuations, but other variables- such as relationship satisfaction - might. Future research may investigate emotional responses in a sample with higher levels of rejection sensitivity and use more diverse measures of perceptions of negative interactions., (© 2024. The Author(s).)
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- 2024
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33. Correction: Attachment insecurities, emotion dynamics and stress in intimate relationships during the transition to parenthood.
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Kouri G, Meuwly N, Richter M, and Schoebi D
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- 2024
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34. Attachment insecurities, emotion dynamics and stress in intimate relationships during the transition to parenthood.
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Kouri G, Meuwly N, Richter M, and Schoebi D
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- Humans, Anxiety, Anxiety Disorders, Emotions, Emotional Regulation
- Abstract
Background: In intimate relationships, which are characterized by emotional interdependence, partners act as attachment figures which serve emotion regulation functions. The experience of emotions as well as the strategies that partners use to regulate them and to respond to relational experiences, especially during stressful periods, differ greatly according to their attachment orientation. An important aspect in emotion dynamics is emotional inertia, which reflects the degree to which a person's current affective state is resistant to change on a moment-to-moment basis. Inertia has been related to maladaptive emotion regulation strategies, like suppression and rumination, preferentially used by highly anxious and avoidant individuals. The aim of this study is to examine associations between attachment orientations and reports on the experience of positive and negative affect, and their dynamics in daily life across the transition to parenthood., Methods: Longitudinal data from a sample of 152 mixed-gender couples collected across the transition to parenthood was analyzed. We predicted that individuals with a more insecure attachment would report more negative and less positive affect, and that their emotional experience would be more resistant to change over time. We explored effects when participants reported feeling stressed., Results: The data suggested that attachment anxiety was associated with less positive and more negative affect and that attachment avoidance was associated with more positive affect. Anxious individuals showed lower emotional inertia and not higher as we expected. Reported stress for anxious and avoidant individuals was significantly associated with more negative but not less positive affect., Conclusions: Results are discussed in the light of their impact on couples during stressful periods. Differences between anxiety and avoidance are found, emphasizing the importance of attachment insecurities on the experience of emotion. Furthermore, our findings on momentary fluctuating affect offer complementary insight into the emotional functioning of individuals with different attachment orientations., (© 2024. The Author(s).)
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- 2024
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35. The visual prostate symptom score is a simple tool to identify and follow up in general practice patients with lower urinary tract symptoms associated with benign prostatic hyperplasia (a study with 1359 patients).
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Descazeaud A, Coloby P, Taille A, Karsenty G, Kouri G, Rossi D, Carrois F, and Zerbib M
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- Aged, Follow-Up Studies, General Practice, Humans, Male, Middle Aged, Prospective Studies, Symptom Assessment, Diagnostic Self Evaluation, Lower Urinary Tract Symptoms diagnosis, Lower Urinary Tract Symptoms etiology, Prostatic Hyperplasia complications
- Abstract
Introduction: The IPSS (International Prostate Symptom Score), a structured self-administered questionnaire is the reference test for evaluation of lower urinary tract symptoms (LUTS). A 5-pictogram score entitled Score Visuel Prostatique en Images (SVPI) was proposed in France and evaluated by urologists. We assessed the interest of the SVPI for the identification and monitoring of benign prostatic hyperplasia (BPH)-related LUTS in general practice, and compared it with the IPSS., Methods: A prospective observational survey was carried out with general practitioners (GPs) throughout France. The first 4consecutive patients aged over 60years, with BPH-related LUTS (IPSS score greater than 8) for whom the GP freely intended to prescribe an alpha-blocker, were enrolled. Two self-administered questionnaires were used at baseline and at follow-up visit (between 1 and 3months): French language version of the IPSS (8questions) and the SVPI. The 5pictograms of the SVPI were: How many times do you urinate during the day (score of 0 to 5)? How many times do you urinate during the night (score of 0 to 5)? Do you experience an urgent need to urinate (score of 0 to 4)? How strong is the stream (response from 0 to 4)? Do you urinate in a satisfactory manner (score of 0 to 6)? The primary objective was to assess and validate the sensitivity to change of the SVPI at baseline and follow-up visit by the study of the correlation of its changes according to the changes of LUTS evaluated with the IPSS., Results: Five hundred and forty seven GPs enrolled at least one patient and returned information. 2261patients completed the inclusion questionnaire, and 1359 were included in the statistical analysis. Under treatment with alpha-blocker, the IPSS average decreased from 17.7±4.9 to 10.5±4.4 (P<0.0001) with an average diminution of 7.2±4.0, which corresponded to an improvement of 40.7%. This significant decrease of the IPSS involved all its components. The total SVPI was evaluated to 13.8±3.1, the irritative sub-score to 7.4±2.0, and the obstructive sub-score to 2.4±0.8. The internal consistency of the SVPI was good with a value of the Cronbach Alpha coefficient of 0.74. Under treatment with alpha-blocker, the value of the total SVPI decreased from 13.8±3.1 to 8.2±3.0 (P<0.0001) between enrolment and the follow-up visit. The Pearson coefficients assessing the correlations in 1359 patients with benign prostatic hypertrophy were statistically significant at enrolment, and at the follow-up visit. Their variations were all significant. The correlations were weak for the obstructive subscores. Four hundred and fifty-one GPs gave their opinion on the SVPI compared to IPSS: for 36.8% of them, the SVPI was completed a little more rapidly than the IPSS, for 34.6% more rapidly, and for 22.8% of them the SVPI was completed much more rapidly. For 5.8% of them, there was no difference. With regard to ease of understanding for the patient, the 451 GPs responded: much easier for 27.3%, easier for 37.3%, a little easier for 27.1%, and 8.4% had no opinion., Conclusion: This study showed the SVPI to be a simple and useful tool for identifying and monitoring BPH-related LUTS. Total SVPI was correlated with total IPSS, even if the obstructive subscore correlation was weaker. The good sensitivity of the SVPI to change showed its potential interest for monitoring LUTS. Given the underuse of the IPSS and the interest expressed by GPs and urologists, the SVPI might be used alone to analyse patient complaints., (Copyright © 2018 Elsevier Masson SAS. All rights reserved.)
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- 2018
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36. Epidemiological studies on dengue virus type 3 in Playa municipality, Havana, Cuba, 2001-2002.
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Guzman MG, Alvarez A, Vazquez S, Alvarez M, Rosario D, Pelaez O, Cruz G, Rodriguez R, Pavon A, Gonzalez A, Morier L, Ruiz D, Kouri G, and Halstead SB
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- Adolescent, Adult, Aged, Aged, 80 and over, Antibodies, Neutralizing blood, Child, Child, Preschool, Coinfection virology, Cuba epidemiology, Epidemiologic Studies, Female, Humans, Male, Middle Aged, Retrospective Studies, Serotyping, Severe Dengue virology, Young Adult, Coinfection epidemiology, Dengue Virus pathogenicity, Disease Outbreaks, Severe Dengue epidemiology
- Abstract
Objectives: Recognizing the uniqueness of secondary dengue virus (DENV)-1/3 dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS) cases at an interval of 24 years, we sought to estimate DENV infections as well as the ratios between mild disease and DHF/DSS by DENV infection sequence in Playa District (Havana, Cuba) during the 2001-2002 outbreak of dengue virus type 3 (DENV-3)., Methods: A retrospective seroepidemiological study was conducted in 2003 in Playa District. Blood samples were collected from a 1% random sample of residents and were studied for the prevalence of dengue neutralizing antibodies., Results: DENV-3 was found to have infected 7.2% (95% confidence interval (95% CI) 6.0-8.4%) of susceptible individuals (the entire cohort), the majority of whom experienced silent infections. Virtually every individual who had a secondary infection in the sequence DENV-1 then DENV-3 became ill, with a ratio of severe to mild cases of 1:35 (95% CI 1:67-1:23). Secondary infections in the sequence DENV-2/3 were less pathogenic than DENV-1/3. Mild disease accompanying secondary DENV2/3 occurred at a ratio of 1:4.49 infections (95% CI 1:5.77-1:3.42) secondary infections., Conclusions: The results obtained highlight the role of the infecting serotype and also the sequence of the viral infection in the clinical outcome of a dengue infection., (Copyright © 2011 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.)
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- 2012
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37. Virus role during intraepidemic increase in dengue disease severity.
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Rodriguez-Roche R, Sanchez L, Burgher Y, Rosario D, Alvarez M, Kouri G, Halstead SB, Gould EA, and Guzman MG
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- Cuba epidemiology, Dengue mortality, Dengue pathology, Dengue Virus genetics, Humans, Mutation, Odds Ratio, Virulence, Virus Replication, Dengue virology, Dengue Virus pathogenicity, Epidemics
- Abstract
Dengue epidemics in Cuba have repeatedly demonstrated a month-to-month increase in clinical severity during secondary infections. The dengue 2 outbreak that occurred in Santiago de Cuba in 1997 was accompanied by the most severe intraepidemic increase in disease severity reported to date. It was initially proposed that the appearance of neutralization escape mutants during the course of the epidemic might explain this phenomenon. Recent studies have revealed that during the course of this epidemic, nucleotide substitutions appeared only in nonstructural (NS) genes, most of which were silent, except for one change in the NS1 gene. To study whether or not variation in the NS1 gene might be associated with increased disease severity during the epidemic, this gene was partially sequenced from 15 isolates obtained at different times during the 1997 epidemic. Early epidemic isolates differed from those obtained later by replacement only of threonine with serine at position 164 in the NS1 protein, an amino acid rarely found in any genotype of dengue 2 virus. All viruses isolated from patients located in Health Districts, where dengue 2 transmissions occurred late in the epidemic, contained Serine at position 164, indicating that this change was fixed within a few months. Here we argue that this single mutation contributes to viral survival or replication efficiency, resulting in enhanced infection in the presence of enhancing antibodies, a phenomenon that we term increased virus "fitness" in contrast to "virulence," an intrinsic property of the virus.
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- 2011
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38. Research priorities for neglected infectious diseases in Latin America and the Caribbean region.
- Author
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Dujardin JC, Herrera S, do Rosario V, Arevalo J, Boelaert M, Carrasco HJ, Correa-Oliveira R, Garcia L, Gotuzzo E, Gyorkos TW, Kalergis AM, Kouri G, Larraga V, Lutumba P, Macias Garcia MA, Manrique-Saide PC, Modabber F, Nieto A, Pluschke G, Robello C, Rojas de Arias A, Rumbo M, Santos Preciado JI, Sundar S, Torres J, Torrico F, Van der Stuyft P, Victoir K, and Olesen OF
- Subjects
- Caribbean Region epidemiology, Communicable Diseases diagnosis, Communicable Diseases drug therapy, Humans, Latin America epidemiology, Neglected Diseases diagnosis, Neglected Diseases drug therapy, Neglected Diseases prevention & control, Biomedical Research trends, Communicable Diseases epidemiology, Neglected Diseases epidemiology, Research
- Published
- 2010
- Full Text
- View/download PDF
39. Randomized, double-blind, placebo-controlled trial to evaluate the safety and immunogenicity of live oral cholera vaccine 638 in Cuban adults.
- Author
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Valera R, García HM, Jidy MD, Mirabal M, Armesto MI, Fando R, García L, Fernández R, Año G, Cedré B, Ramírez M, Bravo L, Serrano T, Palma S, González D, Miralles F, Medina V, Nuñez F, Plasencia Y, Martínez JC, Mandarioti A, Lugones J, Rodríguez BL, Moreno A, González D, Baro M, Solis RL, Sierra G, Barbera R, Domínguez F, Gutiérrez C, Kouri G, Campa C, and Menéndez J
- Subjects
- Administration, Oral, Adolescent, Adult, Antibodies, Bacterial blood, Cholera immunology, Cholera Vaccines adverse effects, Cholera Vaccines immunology, Cuba, Double-Blind Method, Female, Humans, Male, Vaccines, Attenuated administration & dosage, Vaccines, Attenuated adverse effects, Vaccines, Attenuated immunology, Young Adult, Cholera prevention & control, Cholera Vaccines administration & dosage
- Abstract
A randomized, double-blind, placebo-controlled clinical trial was conducted to evaluate the safety, reactogenicity and the immunogenicity of a 2 x 10(9)CFU dose of the 638 lyophilized live attenuated cholera vaccine for oral administration, formulated and produced at Finlay Institute, City of Havana, Cuba. Thirty-six healthy female and male adult volunteers from 18 to 40 years old were involved, clinically examined and laboratory tested after the informed consent signature. Adverse events were monitored and seroconversion rates and geometrical mean titer (GMT) of vibriocidal antibodies were tested in volunteer's sera samples. Neither serious adverse events nor other damages to the volunteers due to vaccine or placebo feeding were reported during the clinical follow-up period of this study; none of the adverse events registered within the first 72 h after inoculation were life-threatening for volunteers. Neither severe nor moderate adverse events were reported. Sixty-one percent of subjects showed mild expected adverse events in an interval lower than 24h up to the first 72 h, 75% of these in the vaccinated group and 18% in the placebo group. Fourteen days after inoculation the GMT of vibriocidal antibodies in the vaccine group significantly increased in comparison to the placebo group. All subjects in the vaccine group (24) seroconverted (100%). Results show that this vaccine is safe, well tolerated and immunogenic in healthy female and male volunteers.
- Published
- 2009
- Full Text
- View/download PDF
40. Dual infection with dengue virus 3 and human immunodeficiency virus 1 in Havana, Cuba.
- Author
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Gonzalez D, Limonta D, Bandera JF, Perez J, Kouri G, and Guzman MG
- Subjects
- Adult, CD4 Lymphocyte Count, Cuba, Dengue epidemiology, Dengue Virus isolation & purification, HIV-1 isolation & purification, Humans, Male, Young Adult, Dengue complications, Dengue diagnosis, HIV Infections complications, HIV Infections diagnosis
- Abstract
Although dengue virus (DEN) endemic regions overlap with human immunodeficiency virus 1 (HIV) high incidence areas, little has been documented on HIV and DEN mixed infection. Here we report DEN/HIV concurrent infections recorded during the DEN-3 epidemic in 2001-2002 in Havana. Serologic-confirmed DEN is described in two HIV-infected subjects with dengue fever symptoms. Although patients had dengue disease, the CD4+ cells remained within normal levels and no accelerated progression of HIV disease was observed. To our knowledge, DEN cases caused by DEN-3 in HIV-infected individuals have not been reported previously. Further research is needed to diagnose this likely underreported mixed viral infection in DEN endemic areas.
- Published
- 2009
- Full Text
- View/download PDF
41. Dengue haemorrhagic fever integral hypothesis: confirming observations, 1987-2007.
- Author
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Guzman MG and Kouri G
- Subjects
- Animals, Cuba epidemiology, Cuba ethnology, Diagnosis, Differential, Disease Outbreaks, Humans, Risk Factors, Severe Dengue complications, Severe Dengue genetics, Aedes parasitology, Dengue Virus pathogenicity, Ecosystem, Severe Dengue epidemiology
- Abstract
In 1987, Kouri et al. published in Transactions their integral hypothesis to explain the development of dengue haemorrhagic fever (DHF) epidemics (Kouri, G.P., Guzmán, M.G., Bravo, J.R., 1987. Why dengue haemorrhagic fever in Cuba? 2. An integral analysis. Trans. R. Soc. Trop. Med. Hyg. 81, 821-823). Based on observations carried out during the 1981 Cuban DHF epidemic, the authors integrated in one model the most advanced knowledge at that time. Observations in the last 20 years confirm the importance of this multifactorial and unifying view of the problem, where the interaction between the host, the virus and the vector in an epidemiological and ecosystem setting might determine DHF as a final outcome. Investigations on the interaction among host, virus and mosquito with an ecosystemic view are needed.
- Published
- 2008
- Full Text
- View/download PDF
42. [Society, economy, inequities and dengue].
- Author
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Kouri G, Pelegrino JL, Munster BM, and Guzmán MG
- Subjects
- Aedes, Animals, Communicable Diseases, Emerging economics, Communicable Diseases, Emerging epidemiology, Dengue economics, Dengue prevention & control, Emigration and Immigration, Global Health, Health Policy, Health Services Accessibility, Humans, Incidence, Insect Vectors, Latin America epidemiology, Mosquito Control, Poverty, Privatization, Social Justice, United States epidemiology, Water Supply, Dengue epidemiology, Socioeconomic Factors
- Abstract
Dengue and dengue hemorrhagic fever in the Americas have been on the rise throughout the 1990s, with the highest number -over one million cases- reported in 2002. This paper analyzed the situation of dengue in the region and discussed the determining factors that account for the rise of the disease, making emphasis on socioeconomic factors, such as poverty, inequality, migrations and the lack of access to basic services, which are the most influential in perpetuating this disease in most countries. Considering that a safe and accessible vaccine is now unavailable, basic principles of vector control combined with political willingness, inter-sectoral involvement, active community participation and the tightening of health legislation were also examined as the only viable solution at present.
- Published
- 2007
43. [The prostate: how to treat this symbol of male vulnerability? An Association Française d'Urologie (AFU)-IPSOS qualitative survey].
- Author
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Yves B, de la Taille A, Chartier-Kastler E, Moreau JL, Davin JL, Mignard JP, Coulange C, Allegre JP, Averous M, Botto H, Coloby P, Conort P, Delmas V, Desgrandchamps F, Fourcade RO, Grall J, Grise P, Kouri G, Le Doze H, Piechaud T, Prunet D, Rambeaud JJ, Rebillard X, Soulie M, Vignes B, and Villers A
- Subjects
- Aging physiology, Attitude of Health Personnel, Attitude to Health, Communication, Digital Rectal Examination, Family Practice education, Female, France, Health Education, Health Promotion, Humans, Interprofessional Relations, Male, Patient Education as Topic, Physician-Patient Relations, Prostate-Specific Antigen analysis, Prostatic Diseases diagnostic imaging, Prostatic Neoplasms diagnostic imaging, Public Health, Referral and Consultation, Ultrasonography, Urology, Mass Screening, Prostatic Diseases diagnosis, Prostatic Neoplasms diagnosis
- Abstract
Introduction: Information on prostate diseases, including prostate cancer, has been promoted by the Association Française d'Urologie (AFU) for several years, but is developing slowly in France. In 2005, a first communication was targeted to the male public and identified the reasons for the fatalistic attitude of men, and paradoxically, why the prostate incarnates the vulnerability of their sexual capital. As part of a second phase, this article presents the results of a complementary study conducted among general practitioners to identify their expectations and the most appropriate levers to promote screening., Material and Method: The Ipsos survey company developed a Krisis qualitative protocol in October 2005 (after the first French prostate day on 15 September 2005). Three groups of general practitioners were defined: doctors who are very active in terms of screening, doctors who are uncomfortable with this problem and doctors who systematically refer their patients to urologists., Results: The management of prostate diseases often highlights the ageing process for the patient. The ability to discuss these problems during the consultation depended on the doctor's degree of comfort with this subject, which is related to his/her training and relationships with urologists. To initiate the question of screening, general practitioners involved in this process asked simple questions about everyday practices without being afraid of making jokes or basing their approach on mediatization of the disease. Digital rectal examination is one of the important clinical elements but is not always easy to perform. PSA was found to be an examination that is not always appropriate, characterized by a lack of information on the conditions for ordering this test, its usefulness and its relevance for screening. Ultrasound could be a way of alerting the patient without dramatizing the situation, letting the urologist perform digital rectal examination. Female general practitioners preferred PSA and ultrasound. The doctors surveyed relied on mediatization of prostate diseases, a high level of interactivity with urologists and documents and brochures to be placed in waiting rooms to relay screening messages., Conclusion: General practitioners need their authorities, specialists and public health institutions to develop and mediatize andrology in the same way as gynaecology. Urologists play a major supportive role by means of conferences, postgraduate training or AFU invitations.
- Published
- 2007
- Full Text
- View/download PDF
44. An integrated ecosystem approach for sustainable prevention and control of dengue in Central Havana.
- Author
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Bonet M, Spiegel JM, Ibarra AM, Kouri G, Pintre A, and Yassi A
- Subjects
- Aedes, Animals, Cuba epidemiology, Dengue transmission, Health Knowledge, Attitudes, Practice, Health Promotion methods, Humans, Insect Vectors, Mosquito Control methods, Mosquito Control organization & administration, Risk Assessment, Community Participation methods, Dengue prevention & control, Ecosystem, Sentinel Surveillance
- Abstract
The authors developed and evaluated a comprehensive participatory ecosystem health approach for preventing the transmission of dengue, the most prevalent vector-borne disease in Cuba and the Latin America-Caribbean region. The integrated surveillance system central to this initiative encompassed three main subsystems (environmental; entomological; clinical-epidemiologic), relying on extensive community involvement. The study was conducted in Central Havana, Cuba. Indicators from each subsystem were selected and mapped using a GIS procedure providing instant visualization by city block in the municipality. To elucidate the factors affecting control and prevention efforts, perceived needs and risks, as well as knowledge, attitudes, and behaviors related to dengue, were assessed. Specific factors associated with the presence of mosquito breeding sites and risks of dengue were examined in a case-control study.
- Published
- 2007
- Full Text
- View/download PDF
45. Neutralizing antibodies after infection with dengue 1 virus.
- Author
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Guzman MG, Alvarez M, Rodriguez-Roche R, Bernardo L, Montes T, Vazquez S, Morier L, Alvarez A, Gould EA, Kouri G, and Halstead SB
- Subjects
- Humans, Neutralization Tests, Antibodies, Viral blood, Dengue immunology, Dengue virology, Dengue Virus classification
- Abstract
Severity of disease is markedly increased when infection with dengue virus type 2 (DENV-2) follows infection with DENV-1 at an interval of 20 years. Studies have shown that heterologous neutralizing antibody titers are inversely correlated with severity of a second infection. If this mechanism controlled disease severity in Cuba, heterotypic antibody titers should have declined over time. To determine whether phenotypic changes in dengue antibodies occur over time, we analyzed serum samples collected 4-8 and 20-22 years after DENV-1 infection. We found a significant increase in mean titer of homologous DENV-1 neutralizing antibodies and a significant decrease in heterologous antibodies to 1 of 2 genotypes of DENV-2 virus (the American genotype). Asian DENV-2 viruses were not neutralized during either interval; however, the American genotype underwent phenotypic changes in heterotypic viral neutralizing antibodies in the predicted direction. This finding may be related to the time-dependent changes in severity of disease found with secondary dengue infection.
- Published
- 2007
- Full Text
- View/download PDF
46. High quality and convenience with digital radiography in pediatric care.
- Author
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Kouri G
- Subjects
- Child, Dental Care for Children instrumentation, Humans, Dental Care for Children methods, Radiography, Dental, Digital
- Published
- 2007
47. Dengue hemorrhagic Fever caused by sequential dengue 1-3 virus infections over a long time interval: Havana epidemic, 2001-2002.
- Author
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Alvarez M, Rodriguez-Roche R, Bernardo L, Vázquez S, Morier L, Gonzalez D, Castro O, Kouri G, Halstead SB, and Guzman MG
- Subjects
- Antibodies, Viral blood, Cuba epidemiology, Dengue Virus classification, Dengue Virus isolation & purification, Humans, Neutralization Tests, Time Factors, Severe Dengue epidemiology
- Abstract
A dengue epidemic caused by dengue virus 3 (DENV-3) occurred in Cuba in 2001-2002. It included cases of dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS). We report neutralizing antibody studies on sera from 54 of 78 DHF/DSS patients that provide evidence of infections occurring in the sequence DENV-1 followed by DENV-3. No sera showed infection in the sequence DENV-2 followed by DENV-3. Some sera showed a pattern of infection in the sequence DENV-1 followed by DENV-2 and then DENV-3. However definitive categorization of a tertiary infection was not possible because of broadly reactive antibodies, which could have been raised by infections in the sequence DENV-1 then DENV-3.
- Published
- 2006
48. ER stress and SREBP-1 activation are implicated in beta-cell glucolipotoxicity.
- Author
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Wang H, Kouri G, and Wollheim CB
- Subjects
- Animals, Cell Line, Diabetes Mellitus, Type 2 metabolism, Gene Expression Regulation, Humans, Insulin metabolism, Insulin-Secreting Cells cytology, Islets of Langerhans cytology, Islets of Langerhans metabolism, Rats, Endoplasmic Reticulum metabolism, Glucose toxicity, Insulin-Secreting Cells metabolism, Lipids toxicity
- Abstract
The reduction in insulin secretory capacity and beta-cell mass observed in type 2 diabetes is thought to be caused by glucolipotoxicity secondary to hyperglycemia and hyperlipidemia. Our aim in this study was to elucidate the underlying molecular mechanisms. We found a strong correlation between chronic high-glucose treatment and SREBP-1c activation in INS-1 cells and rat islets. Both high-glucose treatment and SREBP-1c activation in INS-1 cells resulted in lipid accumulation, impaired glucose-stimulated insulin secretion, apoptosis, and strikingly similar gene expression patterns, including upregulation of lipogenic and pro-apoptotic genes and downregulation of IRS2, Bclxl and Pdx1. These lipotoxic effects of high glucose were largely prevented by induction of a dominant-negative mutant of SREBP-1c, suggesting SREBP-1c is a major factor responsible for beta cell glucolipotoxicity. Moreover, overexpression of another lipogenic transcription factor, ChREBP, in INS-1 cells did not cause lipotoxicity. Intriguingly, chronic high glucose treatment in INS-1 cells led to pronounced induction of the ER stress marker genes, BIP and Chop10. Treatment of rat islets with both chronic high glucose and two ER stress inducers, thapsigargin and tunicamycin, enhanced SREBP-1 binding to the human IRS2 promoter. These results suggest that SREBP-1 activation caused by ER stress is implicated in beta-cell glucolipotoxicity.
- Published
- 2005
- Full Text
- View/download PDF
49. Dengue virus type 3, Cuba, 2000-2002.
- Author
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Rodriguez-Roche R, Alvarez M, Holmes EC, Bernardo L, Kouri G, Gould EA, Halstead S, and Guzman MG
- Subjects
- Cuba epidemiology, Dengue epidemiology, Dengue virology, Disease Outbreaks, Humans, Phylogeny, Dengue Virus genetics
- Published
- 2005
- Full Text
- View/download PDF
50. Virus evolution during a severe dengue epidemic in Cuba, 1997.
- Author
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Rodriguez-Roche R, Alvarez M, Gritsun T, Halstead S, Kouri G, Gould EA, and Guzman MG
- Subjects
- Aedes virology, Animals, Cuba epidemiology, Dengue virology, Dengue Virus classification, Humans, Molecular Sequence Data, Mutation, Phylogeny, Dengue epidemiology, Dengue Virus genetics, Disease Outbreaks, Evolution, Molecular, Severity of Illness Index
- Abstract
Full-length genomic sequences from six DENV-2 isolates sampled at different times during a dengue outbreak that occurred in Cuba in 1997 were determined. Phylogenetic analysis indicated that these isolates fall into the "American/Asian" genotype. Genome analysis revealed strong conservation of the structural proteins and the non-coding regions (5' NCR and 3' NCR). Nucleotide substitutions were observed in non-structural genes and most notably in the NS5 gene. There was a clear pattern of virus evolution during the epidemic; the earliest isolates sampled differed from those sampled later by amino acid replacements in the NS1 and NS5 proteins, although there was no evidence that these represented escape mutants. Further studies are therefore required to define the functional role of amino acid replacements observed and their possible relation to disease severity.
- Published
- 2005
- Full Text
- View/download PDF
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