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29 results on '"Kouni, Sophia N."'

1. Cardio-Oncoimmunology: Cardiac Toxicity, Cardiovascular Hypersensitivity, and Kounis Syndrome

Author

Kounis, Nicholas G., primary, Hung, Ming-Yow, additional, de Gregorio, Cesare, additional, Mplani, Virginia, additional, Gogos, Christos, additional, Assimakopoulos, Stelios F., additional, Plotas, Panagiotis, additional, Dousdampanis, Periklis, additional, Kouni, Sophia N., additional, Maria, Anastasopoulou, additional, Tsigkas, Grigorios, additional, and Koniari, Ioanna, additional

Published
2024
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3. “When”, “Where”, and “How” of SARS-CoV-2 Infection Affects the Human Cardiovascular System: a Narrative Review

Author

Kounis, Nicholas G., primary, Gogos, Christos, additional, Gregorio, Cesare de, additional, Hung, Ming-Yow, additional, Kouni, Sophia N., additional, Tsounis, Efthymios P., additional, Assimakopoulos, Stelios F., additional, Pourmasumi, Soheila, additional, Mplani, Virginia, additional, Servos, George, additional, Dousdampanis, Periklis, additional, Plotas, Panagiotis, additional, Michalaki, Marina A., additional, Tsigkas, Grigorios, additional, Grammatikopoulos, Gerasimos, additional, Velissaris, Dimitrios, additional, and Koniari, Ioanna, additional

Published
2023
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5. The Effect of Long COVID-19 Infection and Vaccination on Male Fertility; A Narrative Review

Author

Pourmasumi, Soheila, primary, Nazari, Alireza, additional, Ahmadi, Zahra, additional, Kouni, Sophia N., additional, de Gregorio, Cesare, additional, Koniari, Ioanna, additional, Dousdampanis, Periklis, additional, Mplani, Virginia, additional, Plotas, Panagiotis, additional, Assimakopoulos, Stelios, additional, Gogos, Christos, additional, Aidonisdis, Georgios, additional, Roditis, Pavlos, additional, Matsas, Nikos, additional, Velissaris, Dimitrios, additional, Calogiuri, Gianfranco, additional, Hung, Ming-Yow, additional, Altay, Servet, additional, and Kounis, Nicholas G., additional

Published
2022
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8. Effects of COVID-19 Infection and Vaccination on the Female Reproductive System: A Narrative Review.

Author

Pourmasumi, Soheila, Kounis, Nicholas G., Nader, Monavar, Hosseinisadat, Robabe, Khoradmehr, Arezoo, Fagheirelahee, Niloofar, Kouni, Sophia N., de Gregorio, Cesare, Dousdampanis, Periklis, Mplani, Virginia, Michalaki, Marina A., Plotas, Panagiotis, Assimakopoulos, Stelios, Gogos, Christos, Aidonidis, Georgios, Roditis, Pavlos, Matsas, Nikos, DimitriosVelissaris, Calogiuri, Gianfranco, and Hung, Ming-Yow

Subjects
OVARIAN physiology, COVID-19, MENSTRUATION disorders, COVID-19 vaccines, OVUM, MENSTRUAL cycle, DISEASES, CHILDBEARING age, CELL physiology, UTERINE diseases, FEMALE reproductive organs, RISK assessment, SEX hormones, REPRODUCTIVE health, WOMEN'S health, ENDOMETRIUM, COVID-19 pandemic
Abstract

Several studies and research papers have been published to elucidate and understand the mechanism of the coronavirus disease 2019 (COVID-19) pandemic and its long-term effects on the human body. COVID-19 affects a number of organs, including the female reproductive system. However, less attention has been given to the effects of COVID-19 on the female reproductive system due to their low morbidity. The results of studies investigating the relationship between COVID-19 infection and ovarian function in women of reproductive age have shown the harmless involvement of COVID-19 infection. Several studies have reported the involvement of COVID-19 infection in oocyte quality, ovarian function, and dysfunctions in the uterine endometrium and the menstrual cycle. The findings of these studies indicate that COVID-19 infection negatively affects the follicular microenvironment and dysregulate ovarian function. Although the COVID-19 pandemic and female reproductive health have been studied in humans and animals, very few studies have examined how COVID-19 affects the female reproductive system. The objective of this review is to summarize the current literature and categorize the effects of COVID-19 on the female reproductive system, including the ovaries, uterus, and hormonal profiles. The effects on oocyte maturation, oxidative stress, which causes chromosomal instability and apoptosis in ovaries, in vitro fertilization cycle, high-quality embryos, premature ovarian insufficiency, ovarian vein thrombosis, hypercoagulable state, women's menstrual cycle, the hypothalamus-pituitary-ovary axis, and sex hormones, including estrogen, progesterone, and the anti- Müllerian hormone, are discussed in particular. [ABSTRACT FROM AUTHOR]

Published
2023
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10. COVID-19 Disease, Women’s Predominant Non-Heparin Vaccine-Induced Thrombotic Thrombocytopenia and Kounis Syndrome: A Passepartout Cytokine Storm Interplay

Author

Kounis, Nicholas G., primary, Koniari, Ioanna, additional, de Gregorio, Cesare, additional, Assimakopoulos, Stelios F., additional, Velissaris, Dimitrios, additional, Hung, Ming-Yow, additional, Mplani, Virginia, additional, Saba, Luca, additional, Brinia, Aikaterini, additional, Kouni, Sophia N., additional, Gogos, Christos, additional, Giovannini, Mattia, additional, Novembre, Elio, additional, Arumugham, Vinu, additional, Ricke, Darrell O., additional, Soufras, George D., additional, Nugent, Kenneth, additional, Sestili, Piero, additional, and Malone, Robert W., additional

Published
2021
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11. COVID-19 Disease, Women’s Predominant Non-Heparin Vaccine-Induced Thrombotic Thrombocytopenia and Kounis Syndrome: A Passepartout Cytokine Storm Interplay

Author

Lincoln Laboratory, Kounis, Nicholas G., Koniari, Ioanna, de Gregorio, Cesare, Assimakopoulos, Stelios F., Velissaris, Dimitrios, Hung, Ming-Yow, Mplani, Virginia, Saba, Luca, Brinia, Aikaterini, Kouni, Sophia N., Gogos, Christos, Giovannini, Mattia, Novembre, Elio, Arumugham, Vinu, Ricke, Nathan Darrell, Soufras, George D., Nugent, Kenneth, Sestili, Piero, Malone, Robert W., Lincoln Laboratory, Kounis, Nicholas G., Koniari, Ioanna, de Gregorio, Cesare, Assimakopoulos, Stelios F., Velissaris, Dimitrios, Hung, Ming-Yow, Mplani, Virginia, Saba, Luca, Brinia, Aikaterini, Kouni, Sophia N., Gogos, Christos, Giovannini, Mattia, Novembre, Elio, Arumugham, Vinu, Ricke, Nathan Darrell, Soufras, George D., Nugent, Kenneth, Sestili, Piero, and Malone, Robert W.

Abstract

Coronavirus disease 2019 (COVID-19) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) constitute one of the deadliest pandemics in modern history demonstrating cardiovascular, gastrointestinal, hematologic, mucocutaneous, respiratory, neurological, renal and testicular manifestations and further complications. COVID-19-induced excessive immune response accompanied with uncontrolled release of cytokines culminating in cytokine storm seem to be the common pathogenetic mechanism of these complications. The aim of this narrative review is to elucidate the relation between anaphylaxis associated with profound hypotension or hypoxemia with pro-inflammatory cytokine release. COVID-19 relation with Kounis syndrome and post-COVID-19 vaccination correlation with heparin-induced thrombocytopenia with thrombosis (HITT), especially serious cerebral venous sinus thrombosis, were also reviewed. Methods: A current literature search in PubMed, Embase and Google databases was performed to reveal the pathophysiology, prevalence, clinical manifestation, correlation and treatment of COVID-19, anaphylaxis with profuse hypotension, Kounis acute coronary syndrome and thrombotic events post vaccination. Results: The same key immunological pathophysiology mechanisms and cells seem to underlie COVID-19 cardiovascular complications and the anaphylaxis-associated Kounis syndrome. The myocardial injury in patients with COVID-19 has been attributed to coronary spasm, plaque rupture and microthrombi formation, hypoxic injury or cytokine storm disposing the same pathophysiology with the three clinical variants of Kounis syndrome. COVID-19-interrelated vaccine excipients as polysorbate, polyethelene glycol (PEG) and trometamol constitute potential allergenic substances. Conclusion: Better acknowledgement of the pathophysiological mechanisms, clinical similarities, multiorgan complications of COVID-19 or other viral infections as dengue and human immunodeficiency viruses along with the

Published
2021

12. Allergic Reactions to Current Available COVID-19 Vaccinations: Pathophysiology, Causality, and Therapeutic Considerations

Author

Kounis, Nicholas G., primary, Koniari, Ioanna, additional, de Gregorio, Cesare, additional, Velissaris, Dimitris, additional, Petalas, Konstantinos, additional, Brinia, Aikaterini, additional, Assimakopoulos, Stelios F., additional, Gogos, Christos, additional, Kouni, Sophia N., additional, Kounis, George N., additional, Calogiuri, GianFranco, additional, and Hung, Ming-Yow, additional

Published
2021
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15. Coronary-Artery Stents

Author

Kounis, Nicholas G., Kounis, George N., and Kouni, Sophia N.

Published
2006

27. Intravenous tissue plasminogen activator, ischemic stroke, and the risk of Kounis Syndrome.

Author

Kounis, Nicholas G., Kouni, Sophia N., Kounis, George N., and Kounis, Sophia A.

Subjects
*TISSUE plasminogen activator, *ALLERGIES, *CEREBROVASCULAR disease, *CORONARY disease, *DIFFERENTIAL diagnosis, *MYOCARDIAL infarction, *SYNDROMES, *THERAPEUTICS
Abstract

A letter to the editor is presented in response to the article "Acute Myocardial Infarction Following Intravenous Tissue Plasminogen Activator for Acute Ischemic Stroke: An Unknown Danger," by A. Sweta et al, in a 2010 issue.

Published
2011
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28. Letter to the Editor.

Author

Kounis, Nicholas G., Kouni, Sophia A., Kouni, Sophia N., and Kounis, George N.

Subjects
LETTERS to the editor, DRUG-eluting stents, THROMBOSIS, CHEMOTAXIS, ALLERGENS, IMMUNOGLOBULIN E receptors
Published
2012
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29. A novel method of brainstem auditory evoked potentials using complex verbal stimuli.

Author

Kouni SN, Koutsojannis C, Ziavra N, and Giannopoulos S

Abstract

Background: The click and tone-evoked auditory brainstem responses are widely used in clinical practice due to their consistency and predictability. More recently, the speech-evoked responses have been used to evaluate subcortical processing of complex signals, not revealed by responses to clicks and tones., Aims: Disyllable stimuli corresponding to familiar words can induce a pattern of voltage fluctuations in the brain stem resulting in a familiar waveform, and they can yield better information about brain stem nuclei along the ascending central auditory pathway., Materials and Methods: We describe a new method with the use of the disyllable word "baba" corresponding to English "daddy" that is commonly used in many other ethnic languages spanning from West Africa to the Eastern Mediterranean all the way to the East Asia., Results: This method was applied in 20 young adults institutionally diagnosed as dyslexic (10 subjects) or light dyslexic (10 subjects) who were matched with 20 sex, age, education, hearing sensitivity, and IQ-matched normal subjects. The absolute peak latencies of the negative wave C and the interpeak latencies of A-C elicited by verbal stimuli "baba" were found to be significantly increased in the dyslexic group in comparison with the control group., Conclusions: The method is easy and helpful to diagnose abnormalities affecting the auditory pathway, to identify subjects with early perception and cortical representation abnormalities, and to apply the suitable therapeutic and rehabilitation management.

Published
2014
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