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35 results on '"Koulchitsky Stanislav"'

6. Experimental Verification of Hypothesis of Antitumor Potential Presence in Mesenchymal Stem Cells

Author

Pašukonienė Vita, Suziedelis Kestusis, Takalchyk Yulya, Koulchitsky Stanislav, Navitskaya Valeria, Kuznetsova Tatiana, Shanko Yuri, Pashkevich Svetlana, Kulchitsky Vladimir, Dosina Margarita, Kaliadzich Zhanna, Khotin Vitaly, Krivenchuk Dmitry, and Zamaro Alexandra

Subjects
business.industry, Mesenchymal stem cell, Treatment method, General Medicine, Hypoxia (medical), medicine.disease_cause, Tissue damage, Cancer research, Medicine, medicine.symptom, Stem cell, business, Carcinogenesis, Immunosuppressive effect
Abstract

Experimental Verification of Hypothesis of Antitumor Potential Presence in Mesenchymal Stem Cells is an analgesic treatment method which is applied before surgical trauma and tissue damage..

Published
2020
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8. Does Technique of Mesenchymal Stem Cells Perineural Migration Seem Promising in Technologies of Combined Therapy with Stem Cells?

Author

Koulchitsky Stanislav, Navitskaya Valeria, Shanko Yuri, Zamaro Aleksandra, and Kulchitsky Vladimir

Subjects
Modern medicine, Pathology, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Lumbar puncture, Cranial nerves, Mesenchymal stem cell, General Medicine, Cell therapy, Cerebrospinal fluid, Combined therapy, Medicine, Stem cell, business
Abstract

The progress of modern medicine is also associated with highcost technologies, expensive creation of medicines, and unique ways of transplantations of inner organs, which are available only for selected people [1].

Published
2019
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10. Typing and Antifungal Susceptibility of Candida Spp. Isolated from Clinical Samples

Author

Alinia-Ahandani, Koulchitsky Stanislav, Zamaro Alexandra, and Kulchitsky Vladimir

Subjects
biology, business.industry, medicine.medical_treatment, General Medicine, Fungus, medicine.disease, Vagotomy, biology.organism_classification, Vagus nerve, Microbiology, Neurotrophic factors, Diabetes mellitus, Amphotericin B, medicine, Candida spp, Typing, business, medicine.drug
Published
2019
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11. Perineural Way of Stem Cells Migration to Injured Heart Regions

Author

Pashkevich Svetlana, Filatova Daria, Zamaro Aleksandra, Kalvinkovskaya Julia, Hubkin Siarhei, Ablomeiko Antonina, Shanko Yuri, Dosina Margarita, Sushko Timur, Kuznetsova Tatiana, Bushuk Sergei, Kulchitsky Vladimir, Koulchitsky Stanislav, and Stukach Yulya

Subjects
Pathology, medicine.medical_specialty, business.industry, medicine.medical_treatment, Cardiac muscle, General Medicine, 030204 cardiovascular system & hematology, medicine.disease, Vagotomy, Vagus nerve, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, nervous system, 030220 oncology & carcinogenesis, Medicine, Myocardial infarction, Stem cell, business, Biomedical sciences
Abstract

Hypothesis on reality of perineural migration of stem cells (SCs) along vagus nerve fibers to injured heart and brain stem regions was experimentally verified on ten Wistar rats.

Published
2019
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14. Tumor Cell Survival Secrets

Author

Zhu, Junlan, primary, Zamaro, Alexandra, additional, Kuznetsova, Tatiana, additional, Koulchitsky, Stanislav, additional, Suziedelis, Kestutis, additional, Takalchyk, Yulya, additional, Shanko, Yuri, additional, and Kulchitsky, Vladimir, additional

Published
2020
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15. Topical Issues of Bioprinting Technology

Author

Denisov Andrew, Kulchitsky Vladimir, Koulchitsky Stanislav, Krivenchuk Dmitry, and Zamaro Alexandra

Subjects
Computer science, General Medicine, Brain tissue, Biomedical engineering
Abstract

Brief analysis of positive and negative aspects of bioprinting was performed. Bioprinting has technical deficiencies and a range of unresolved issues, including the absence of bioprinting protocol strategy...

Published
2018
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16. The Role of Feedback in Breathing Self-Regulation in Health and Obstructive Sleep Apnea Syndrome Development

Author

Zaykina Natalia, Koulchitsky Stanislav, Kulchitsky Vladimir, Andrianova Tatiana, Dosina Margarita, Zamaro Alexandra, Yaromenka Yuliya, Kaliadzich Zhanna, Semenik-Philipovich Tatiana, Hudny Gennady, and Krivenchuk Dmitry

Subjects
medicine.medical_specialty, Medullary cavity, business.industry, Respiratory arrest, Apnea, General Medicine, respiratory system, medicine.disease, respiratory tract diseases, Obstructive sleep apnea, nervous system, Internal medicine, medicine, Cardiology, In patient, medicine.symptom, business, hormones, hormone substitutes, and hormone antagonists, Biomedical sciences
Abstract

Hypothesis on efficiency of feedback from medullary chemoreceptors (MCh) which react to carbon dioxide excess in the organism was tested in patients with obstructive sleep apnea syndrome (OSAS)...

Published
2018
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17. Anti-Epileptic Drugs, Would They be the Cause of Heterotopic Ossification

Author

Saloua Khalfaoui, Shanko Yuri, Navitskaya Valeria, Hafid Arabi, and Koulchitsky Stanislav

Subjects
Valproic Acid, medicine.medical_specialty, Prolonged immobilization, medicine.diagnostic_test, business.industry, Radiography, Computed tomography, General Medicine, medicine.disease, Surgery, Epilepsy, medicine, Heterotopic ossification, Risk factor, business, Biomedical sciences, medicine.drug
Abstract

Etiopathogenesis of Heterotopic ossification or paraosteoarthropathy is unknown, all speculations remain open. Epilepsy and anti-epileptic drugs have never been mentioned as a risk factor...

Published
2018
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18. Regulatory Effects of Mesenchymal Stem Cells in Brain

Author

Shanko Yuri, Zamaro Alexandra, Navitskaya Valeria, Kulchitsky Vladimir, and Koulchitsky Stanislav

Subjects
Brain-derived neurotrophic factor, Neurotrophic factors, Neuroplasticity, Mesenchymal stem cell, General Medicine, Biology, Stem cell, Transcription factor, Pathological, Neuroscience, Biomedical sciences
Abstract

The question on various functional effects of mesenchymal stem cells (MSCs) during different pathological processes development in brain was considered...

Published
2018
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19. Prospects of Perineural Implantation of Stem Cells in Recovery of Neural Network’s Functions in Brain Diseases

Author

Aftab Ahmed, Koulchitsky Stanislav, Sara Isthaq, Kulchitsky Vladimir, Darosham Sohail Khan, Usman Naeem, Muhammad Nadeem, Zamaro Alexandra, Shanko Yuri, Muhammad Aslam, and MMuhammad Imran

Subjects
medicine.anatomical_structure, Artificial neural network, business.industry, medicine, General Medicine, Stem cell, business, Umbilical cord, Neuroscience
Published
2018
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20. Tissue Engineering Therapy for Unhealed Diabetic Wound Using Mononuclear Stem Cells, Plasma Rich Platelets and Collagen

Author

Usman Naeem, Koulchitsky Stanislav, Basuki Supartono, Darosham Sohail Khan, Zamaro Alexandra, Muhammad Aslam, Aftab Ahmed, MMuhammad Imran, Shanko Yuri, Muhammad Nadeem, and Sara Isthaq

Subjects
Pathology, medicine.medical_specialty, business.industry, General Medicine, Gradient centrifugation, medicine.disease, Povidone-Iodine Solution, Diabetic wound, Neovascularization, Tissue engineering, Diabetes mellitus, medicine, Platelet, Stem cell, medicine.symptom, business
Published
2018
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21. Ecofriendly Dentistry: Save Today for a Better Tomorrow

Author

Gangishetti SaiRam, Tomar Singh Prashant, Koulchitsky Stanislav, Yadav Karthik D, Denisov Andrew, Sindhe J Raghunand, Kulchitsky Vladimir, Jordi Carratalà, Pashkevich Svetlana, and Takalchik Stukach Yulya

Subjects
Engineering, business.industry, Engineering ethics, General Medicine, business
Published
2018
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22. Effects of Climate Change in Aquaculture: Case study in Thua Thien Hue Province, Vietnam

Author

Kulchitsky Vladimir, Sindhe J Raghunand, Yadav Karthik D, Denisov Andrew, Koulchitsky Stanislav, Jordi Carratalà, Gangishetti SaiRam, Pashkevich Svetlana, Takalchik Stukach Yulya, and Le Duc Ngoan

Subjects
0106 biological sciences, 010504 meteorology & atmospheric sciences, business.industry, 010604 marine biology & hydrobiology, Aquatic animal, General Medicine, 01 natural sciences, Fishery, Geography, Habitat destruction, Aquaculture, Effects of global warming, business, 0105 earth and related environmental sciences, Hue
Published
2018
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23. Steroid Myopathy: Understanding the Pathogenesis

Author

Kulchitsky Vladimir, Denisov Andrew, Monica Canepari, Takalchik Stukach Yulya, Pashkevich Svetlana, Jordi Carratalà, Rezvan Pourahmad, Mohammad Alizadeh Khaledabad, Asghar Khosrowshahi, and Koulchitsky Stanislav

Subjects
Inhibition zone, biology, business.industry, Chronic gastritis, General Medicine, biology.organism_classification, medicine.disease, Pathogenesis, Levofloxacin, Immunology, medicine, Helicobacter, business, Bifidobacterium, Steroid Myopathy, medicine.drug
Published
2018
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24. Prevalence and Associated Factors of Low Back Pain Among Teachers Working at Governmental Primary Schools in Addis Ababa, Ethiopia: A Cross Sectional Study

Author

Tsega-Ab Abebaw, Denisov Andrew, Bereket Gebremichael, Pashkevich Svetlana, Admas Abera Abaerei, Mitslal Kidane Weldegebriel, Jordi Carratalà, Koulchitsky Stanislav, Zafranskaya Marina, Takalchik Stukach Yulya, and Kulchitsky Vladimir

Subjects
medicine.medical_specialty, business.industry, Cross-sectional study, Public health, Air pollution, General Medicine, medicine.disease_cause, Low back pain, Road transport, Environmental health, Life expectancy, Medicine, medicine.symptom, business, Risk assessment
Published
2018
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25. Prospects of Perineural Administration of Autologous Mesenchymal Stem Cells of Adipose Tissue in Patients with Cerebral Infarction

Author

Koulchitsky Stanislav, Zafranskaya Marina, Denisov Andrew, Pashkevich Svetlana, Shanko Yuri, Kulchitsky Vladimir, Krivenko Svetlana, Navitskaya Valeria, Takalchik Stukach Yulya, Jordi Carratalà, and Zamaro Alexandra

Subjects
Nasal cavity, Pathology, medicine.medical_specialty, Cerebral infarction, business.industry, Mesenchymal stem cell, Glasgow Coma Scale, Adipose tissue, General Medicine, medicine.disease, Cell therapy, medicine.anatomical_structure, medicine, In patient, Stem cell, business
Published
2018
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27. Prospects for Improving the Effectiveness of Chemotherapy in Patients with Tumors

Author

Kletskov Alexey, Darinskas Adas, Kulchitsky Vladimir, Suziedelis Kestusis, Potkin Vladimir, Denisov Andrew, Koulchitsky Stanislav, Sushko Timur, Pašukonienė Vita, Alexandrova Radostina, Pashkevich Svetlana, Zamaro Alexandra, and Dosina Margarita

Subjects
Oncology, medicine.medical_specialty, Chemotherapy, business.industry, medicine.medical_treatment, Internal medicine, medicine, In patient, General Medicine, business
Published
2018
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28. Effect of a calcitonin gene-related peptide-binding L-RNA aptamer on neuronal activity in the rat spinal trigeminal nucleus

Author

Fischer, Michael J. M., Schmidt, Jakob, Koulchitsky, Stanislav, Klussmann, Sven, Vater, Axel, and Messlinger, Karl

Subjects
Male, Neurons, Nociception, Calcitonin Gene-Related Peptide, Migraine Disorders, lcsh:R, Headache, lcsh:Medicine, Aptamers, Nucleotide, Rats, Disease Models, Animal, Meninges, Medizinische Fakultät, Meningeal nociception, Animals, RNA, ddc:610, Rats, Wistar, Trigeminal Nucleus, Spinal, Migraine, Research Article, Receptors, Calcitonin Gene-Related Peptide
Abstract

Background Calcitonin gene-related peptide (CGRP) plays a major role in the pathogenesis of migraine and other primary headaches. Spinal trigeminal neurons integrate nociceptive afferent input from trigeminal tissues including intracranial afferents, and their activity is thought to reflect facial pain and headache in man. CGRP receptor inhibitors and anti-CGRP antibodies have been demonstrated to be therapeutically effective in migraine. In parallel, CGRP receptor inhibition has been shown to lower spinal trigeminal neuron activity in animal models of meningeal nociception. Methods In a rat model of meningeal nociception, single cell activity of neurons in the spinal trigeminal nucleus with meningeal afferent input was recorded to test a further pharmacological approach, scavenging CGRP with a CGRP-binding l-RNA oligonucleotide, the l-aptamer NOX-C89. Cumulative ascending doses of NOX-C89 were intravenously infused. Results Spontaneous activity of spinal trigeminal neurons did not change after 0.05 mg/kg NOX-C89, however, after additional infusion of 0.5 mg/kg and 5 mg/kg NOX-C89, spontaneous activity was dose-dependently reduced. Identical doses of a control l-aptamer had no effect. This pharmacological effect of NOX-C89 was observed 10–25 min after infusion, but no difference was detected in the period 0–5 min. For comparison, the previously investigated CGRP receptor antagonist olcegepant had reduced activity within 5 min after infusion. Alongside the reduced spontaneous activity, after infusion of NOX-C89 the heat-induced neuronal activity was abolished. Conclusions Scavenging CGRP by mirror-image RNA aptamers provides further evidence that this approach can be used to control spinal trigeminal activity.

Published
2018

31. Changed state – changed brain: shift of the dominant frequency of theta oscillations in the rat VTA during stereotypic locomotion

Author

Monteforte Alexandre, Beeken Thom, Dethier Julie, Findeisen Rolf, Quertemont Etienne, Seutin Vincent, Bullinger Eric, and Koulchitsky Stanislav

Subjects
Behavioral Neuroscience, Psychiatry and Mental health, Neuropsychology and Physiological Psychology, Neurology, Brain shift, State (functional analysis), Dominant frequency, Psychology, Neuroscience, Theta oscillations, Biological Psychiatry
Published
2014
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35. The Nonpeptide Calcitonin Gene-Related Peptide Receptor Antagonist BIBN4096BS Lowers the Activity of Neurons with Meningeal Input in the Rat Spinal Trigeminal Nucleus.

Author

Marco Fischer, Michael Jochen, Koulchitsky, Stanislav, and Messlinger, Karl

Subjects
*CALCITONIN gene-related peptide, *MIGRAINE, *TRIGEMINAL nerve, *FACIAL pain, *NEUROPEPTIDES
Abstract

Calcitonin gene-related peptide (CGRP) has been suggested to play a major role in the pathogenesis of migraines and other primary headaches. CGRP may be involved in the control of neuronal activity in the spinal trigeminal nucleus (STN), which integrates nociceptive afferent inputs from trigeminal tissues, including intracranial afferents. The activity of STN neurons is thought to reflect the activity of central trigeminal nociceptive pathways causing facial pain and headaches in humans. In a rat model of meningeal nociception, single neuronal activity in the STN was recorded. All units had receptive fields located in the exposed parietal dura mater. Heat and cold stimuli were repetitively applied to the dura in a fixed pattern of ramps and steps. The nonpeptide CGRP receptor antagonist BIBN4096BS was topically applied onto the exposed dura or infused intravenously. BIBN4096BS (300 µg/kg, i.v.) reduced spontaneous activity by ∼30%, the additional dose of 900 µg/kg intravenously by ∼50% of the initial activity, whereas saline had no effect. The activity evoked by heat ramps was also reduced after BIBN4096BS (900 µg/kg, i.v.) by ∼50%. Topical administration of BIBN4096BS (1 mM) did not significantly change the spontaneous neuronal activity within 15 min. We conclude that the endogenous release of CGRP significantly contributes to the maintenance of spontaneous activity in STN neurons. Blockade of CGRP receptors, possibly at central and peripheral sites, may therefore be an effective way to decrease nociceptive transmission. This may offer a new therapeutic strategy for the treatment of facial pain and primary headaches. [ABSTRACT FROM AUTHOR]

Published
2005
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