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574 results on '"Kopylov, U"'

9. P510 Relapse rate following withdrawal of vedolizumab and ustekinumab in patients with inflammatory bowel disease. The VEDUST-EXIT study

Author

Albshesh, A, primary, Kucha, P, additional, Mahajna, H, additional, Amiot, A, additional, Abitbol, C M, additional, Eder, P, additional, Imperatore, N, additional, Krznaric, Z, additional, Zaborowska, M, additional, Zagórowicz, E, additional, Carbonnel, F, additional, Zittan, E, additional, Ben-Horin, S, additional, and Kopylov, U, additional

Published
2024
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10. DOP09 Models for predicting Crohn Disease (CD) exacerbation using serum and fecal metabolomics

Author

Levhar, N, primary, Hadar, R, additional, Braun, T, additional, Efroni, G, additional, Naamneh, R, additional, Agranovich, B, additional, Talan Asher, A, additional, Selinger, L, additional, Picard, O, additional, Lahat, A, additional, Eliakim, A, additional, Kopylov, U, additional, Ben-Horin, S, additional, Amir, A, additional, and Haberman, Y, additional

Published
2024
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13. P663 Efficacy of jak inhibitors in inflammatory bowel disease patients with extraintestinal manifestations– Retrospective study

Author

Livne Margolin, M, primary, González Lama2, Y, additional, Koutroubakis, I, additional, Drygiannakis, I, additional, Shitrit, A, additional, Goldenberg, R, additional, Farkas, K, additional, Molnar, T, additional, Ivány, E, additional, Amiot, A, additional, Carbonnel, F, additional, Girod, P, additional, Doherty, G, additional, Mateescu, B, additional, Ben-Horin1, S, additional, and Kopylov, U, additional

Published
2024
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17. DOP29 Capsule endoscopy-guided proactive treatment versus standard treatment of patients with quiescent Crohn’s Disease: The CURE-CD randomized controlled trial

Author

Ben-Horin, S, primary, Lahat, A, additional, Ungar, B, additional, Ukashi, O, additional, Yablecovitch, D, additional, Amitai, M M, additional, Haberman, Y, additional, Selinger, L, additional, Talan-Asher, A, additional, Kriger-Sharabi, O, additional, Naftali, T, additional, Ron, Y, additional, Yanai, H, additional, Dotan, I, additional, Kopylov, U, additional, and Eliakim, R, additional

Published
2024
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21. Deep learning multi-domain model provides accurate detection and grading of mucosal ulcers in different capsule endoscopy types

Author

Margalit Yehuda, R., additional, Kratter, T., additional, Shapira, N., additional, Lev, Y., additional, Mauda, O., additional, Moshkovitz, Y., additional, Shitrit, R., additional, Konyo, S., additional, Ukashi, O., additional, Dar, L., additional, Shlomi, O., additional, Albshesh, A., additional, Soffer, S., additional, Klang, E., additional, Ben-Horin, S., additional, Eliakim, R., additional, and Kopylov, U., additional

Published
2023
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26. Idiopathic Thrombocytopaenic Purpura associated with Inflammatory Bowel Disease: a multicentre ECCO CONFER case series.

Author

Mahajna, H., Verstockt, B., Bergemalm, D., Castiglione, F., Rodríguez-Moranta, F., Savarino, E., Hoentjen, F., Bessissow, T., Pokryszka, J., Cremer, A., Eder, P., Truyens, M., Yerushalmy-Feler, A., García, M.J., Kopylov, U., Mahajna, H., Verstockt, B., Bergemalm, D., Castiglione, F., Rodríguez-Moranta, F., Savarino, E., Hoentjen, F., Bessissow, T., Pokryszka, J., Cremer, A., Eder, P., Truyens, M., Yerushalmy-Feler, A., García, M.J., and Kopylov, U.

Abstract

Item does not contain fulltext, BACKGROUND: Idiopathic thrombocytopaenic purpura [ITP] is an acquired haematological disorder with an incidence of 1-6 per 100 00/year. ITP and inflammatory bowel disease [IBD] comorbidity has been reported in the literature, but insights regarding the course, outcome and optimal management are limited by its rarity. The current study aimed to evaluate the clinical presentation and outcome of ITP in patients with IBD. METHODS: This multicentre retrospective case series was performed as part of the ECCO Collaborative Network of Exceptionally Rare case reports [CONFER] project. Cases of patients with ITP and IBD were collected by participating investigators. Clinical data were recorded in a standardized collection form. RESULTS: This report includes 32 patients with concurrent ITP and IBD: ten were females, and the median age was 32.0 years (interquartile range [IQR] 20.5-39.5). Fourteen patients had a diagnosis of Crohn's disease [CD] and the other 18 ulcerative colitis [UC]. The diagnosis of IBD preceded the ITP in 26 patients (median time between diagnoses was 7.0 years [IQR, 1.5-9.5]). Among those patients, 17 were in clinical remission at ITP diagnosis. Thirteen patients were treated with mesalamine, four with oral corticosteroids, one with rectal corticosteroids, two with azathioprine and five with anti-tumour necrosis factor agents. The median platelet count was 35 000/microliter [IQR, 10 000-70 000]. Eight patients had rectal bleeding, 13 had skin purpura, three had epistaxis, six had mucosal petechiae and 13 were asymptomatic. Regarding ITP treatment, 19 were treated with corticosteroids, one with anti-RhD immunoglobulin, 12 with intravenous immunoglobulins [IVIGs], four with thrombopoietin, three with rituximab and six patients eventually required splenectomy. Ten patients needed no treatment directed to the ITP. Three patients required colectomy during long-term follow-up, due to IBD or cancer but not to massive bleeding as a complication of ITP. One of eig

Published
2023

27. ECCO Guidelines on Inflammatory Bowel Disease and Malignancies.

Author

Gordon, H., Biancone, L., Fiorino, G., Katsanos, K.H., Kopylov, U., Sulais, E. Al, Axelrad, J.E., Balendran, K., Burisch, J., Ridder, L., Derikx, L.A.A.P., Ellul, P., Greuter, T., Iacucci, M., Jiang, C., Kapizioni, C., Karmiris, K., Kirchgesner, J., Laharie, D., Lobatón, T., Molnár, T., Noor, N.M., Rao, R., Saibeni, S., Scharl, M., Vavricka, S.R., Raine, T., Gordon, H., Biancone, L., Fiorino, G., Katsanos, K.H., Kopylov, U., Sulais, E. Al, Axelrad, J.E., Balendran, K., Burisch, J., Ridder, L., Derikx, L.A.A.P., Ellul, P., Greuter, T., Iacucci, M., Jiang, C., Kapizioni, C., Karmiris, K., Kirchgesner, J., Laharie, D., Lobatón, T., Molnár, T., Noor, N.M., Rao, R., Saibeni, S., Scharl, M., Vavricka, S.R., and Raine, T.

Abstract

Item does not contain fulltext

Published
2023

30. P777 Deployment of an artificial intelligence tool for precision medicine in ulcerative colitis: Preliminary data from 8 globally distributed clinical sites

Author

Peyrin-Biroulet, L, primary, Rubin, D, additional, Weber, C, additional, Adsul, S, additional, Freire, M, additional, Biedermann, L, additional, Koelzer, V, additional, Bressler, B, additional, Xiong, W, additional, Niess, J, additional, Matthias Matter, M M, additional, Kopylov, U, additional, Barshack, I, additional, Mayer, C, additional, Magro, F, additional, Carneiro, F, additional, Maharshak, N, additional, Greenberg, A, additional, Hart, S, additional, Dehmeshki, J, additional, and Kubassova, O, additional

Published
2023
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33. P560 Curcumin-QingDai combination for patients with active ulcerative colitis: A randomized double-blinded placebo-controlled trial

Author

Ben-Horin, S, primary, Salomon, N, additional, Karampekos, G, additional, Viazis, N, additional, Lahat, A, additional, Ungar, B, additional, Eliakim, R, additional, Kriger-Sharabi, O, additional, Reiss-Mintz, H, additional, Yanai, H, additional, Dotan, I, additional, Zittan, E, additional, Maharshak, N, additional, Hirsch, A, additional, Weitman, M, additional, Mantzaris, G J, additional, and Kopylov, U, additional

Published
2023
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34. P046 Crohn Disease (CD) untargeted fecal metabolome shows strong correlation with specific salivary associated microbial taxa, and with disease activity

Author

Levhar, N, primary, Hadar, R, additional, Braun, T, additional, Efroni, G, additional, Abramovich, I, additional, Gottlieb, E, additional, Granot, M, additional, Neuman, S, additional, Selinger, L, additional, Picard, O, additional, Yavzori, M, additional, Lahat, A, additional, Eliakim, R, additional, Weiss, B, additional, Kopylov, U, additional, Ben-Horin, S, additional, Amir, A, additional, and Haberman Ziv, Y, additional

Published
2023
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38. P004 Untargeted serum metabolome shows Crohn Disease (CD) associated signature, signals that correlate with disease activity and CRP, and signals that may precede disease flare

Author

Levhar, N, primary, Hadar, R, additional, Braun, T, additional, Efroni, G, additional, Abramovich, I, additional, Gottlieb, E, additional, Granot, M, additional, Sandra, N, additional, Selinger, L, additional, Picard, O, additional, Yavzori, M, additional, Lahat, A, additional, Eliakim, R, additional, Weiss, B, additional, Kopylov, U, additional, Ben-Horin, S, additional, Amir, A, additional, and Haberman Ziv, Y, additional

Published
2023
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43. Magnetic resonance enterography or video capsule endoscopy – what do Crohn’s disease patients prefer?

Author

Lahat A, Kopylov U, Amitai MM, Neuman S, Levhar N, Yablecovitch D, Avidan B, Yanai H, Dotan I, Chowers Y, Weiss B, Ben-Horin S, and Eliakim R

Subjects
Inflammatory Bowel Disease, Crohn's, imaging, MRE, capsule endoscopy, patients preference, Medicine (General), R5-920
Abstract

Adi Lahat,1,2 Uri Kopylov,1,2 Marianne M Amitai,3 Sandra Neuman,1,2 Nina Levhar,1,2 Doron Yablecovitch,1,2 Benjamin Avidan,1,2 Henit Yanai,2,4 Iris Dotan,2,4 Yehuda Chowers,5,6 Batya Weiss,7 Shomron Ben-Horin,1,2,* Rami Eliakim1,2,* On behalf of the Israeli IBD Research Network (IIRN) 1Department of Gastroenterology, Chaim Sheba Medical Center, Tel Hashomer, Israel; 2Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; 3Department of Diagnostic Imaging, Chaim Sheba Medical Center, Tel Hashomer, Israel; 4IBD Center, Department of Gastroenterology and Liver Diseases, Tel Aviv Medical Center, Tel Aviv, Isarel; 5Rambam Health Care Campus, Haifa, Israel; 6Bruce Rappaport School of Medicine, Technion Israel Institute of Technology, Haifa, Israel; 7Edmond and Lily Safra Children’s Hospital, Tel Hashomer, Israel *These authors contributed equally to this work Background: Despite differences in the information obtained by capsule endoscopy (CE) and magnetic resonance enterography (MRE), one of these modalities is usually needed when evaluating disease activity. There are no data on patients’ preference that would help guide the choice between these two modalities in these instances.Aim: To compare patients’ tolerance and preference to MRE versus CE.Patients and methods: Patients with known small bowel Crohn’s disease (CD) in clinical remission (Crohn’s disease activity index [CDAI]

Published
2016

45. LINEE GUIDA EUROEE

Author

Gordon, H, Biancone, L, Fiorino, G, Katsanos, K, Kopylov, U, Sulais, E, Axelrad, J, Balendran, K, Burisch, J, de Ridder, L, Derikx, L, Ellul, P, Greuter, T, Iacucci, M, Di Jiang, C, Kapizioni, C, Karmiris, K, Kirchgesner, J, Laharie, D, Lobatón Ortega, T, Molnár, T, Noor, N, Rao, R, Saibeni, S, Scharl, M, Vavricka, S, and Raine, T

Subjects
Settore MED/12
Published
2022

47. Development of a core descriptor set for Crohn's anal fistula

Author

Lee M. J., Williams K. M., Lamidi S., Coe P. O., Bordeianou L. G., Hart A. L., Hind D., Lindsay J. O., Lobo A. J., Myrelid P., Raine T., Sebastian S., Fearnhead N. S., Adams K., Almer S., Ananthakrishnan A., Bethune R. M., Block M., Brown S. R., Cirocco W. C., Cooney R., Davies J., Atici S. D., Dhar A., Din S., Drobne D., Espin-Basany E., Evans J. P., Fleshner P. R., Folkesson J., Fraser A., Graf W., Hahnloser D., Hager J., Hancock L., Hanzel J., Hargest R., Hedin C. R. H., Hill J., Ihle C., Jongen J., Kader R., Karmiris K., Katsanos K. H., Keller D. S., Kopylov U., Koutrabakis I. E., Lamb C. A., Landerholm K., Lee G. C., Litta F., Limdi J. K., Lopes E. W., Madoff R. D., Martin S. T., Martin-Perez B., Michalopoulos G., Millan M., Munch A., Nakov R., Noor N. M., Oresland T., Paquette I. M., Pellino G., Perra T., Porcu A., Roslani A. C., Samaan M. A., Sebepos-Rogers G. M., Segal J. P., de Silva S., Soderholm M., Spinelli A., Speight A., Steinhagen R. M., Stenstrom P., Tsimogiannis K. E., Varma M. G., Verma A. M., Verstockt B., Warden C., Yassin N., Zawadzki A., Carr P., Devlin B., Mannick S., Avery P., Gecse K. B., Goren I., Hellstrom P. M., Kotze P. G., McWhirter D., Naik A. S., Sammour T., Selinger C. P., Stein S. L., Torres J., Wexner S. D., Younge L. C., Lee, M. J., Williams, K. M., Lamidi, S., Coe, P. O., Bordeianou, L. G., Hart, A. L., Hind, D., Lindsay, J. O., Lobo, A. J., Myrelid, P., Raine, T., Sebastian, S., Fearnhead, N. S., Adams, K., Almer, S., Ananthakrishnan, A., Bethune, R. M., Block, M., Brown, S. R., Cirocco, W. C., Cooney, R., Davies, J., Atici, S. D., Dhar, A., Din, S., Drobne, D., Espin-Basany, E., Evans, J. P., Fleshner, P. R., Folkesson, J., Fraser, A., Graf, W., Hahnloser, D., Hager, J., Hancock, L., Hanzel, J., Hargest, R., Hedin, C. R. H., Hill, J., Ihle, C., Jongen, J., Kader, R., Karmiris, K., Katsanos, K. H., Keller, D. S., Kopylov, U., Koutrabakis, I. E., Lamb, C. A., Landerholm, K., Lee, G. C., Litta, F., Limdi, J. K., Lopes, E. W., Madoff, R. D., Martin, S. T., Martin-Perez, B., Michalopoulos, G., Millan, M., Munch, A., Nakov, R., Noor, N. M., Oresland, T., Paquette, I. M., Pellino, G., Perra, T., Porcu, A., Roslani, A. C., Samaan, M. A., Sebepos-Rogers, G. M., Segal, J. P., de Silva, S., Soderholm, M., Spinelli, A., Speight, A., Steinhagen, R. M., Stenstrom, P., Tsimogiannis, K. E., Varma, M. G., Verma, A. M., Verstockt, B., Warden, C., Yassin, N., Zawadzki, A., Carr, P., Devlin, B., Mannick, S., Avery, P., Gecse, K. B., Goren, I., Hellstrom, P. M., Kotze, P. G., Mcwhirter, D., Naik, A. S., Sammour, T., Selinger, C. P., Stein, S. L., Torres, J., Wexner, S. D., Younge, L. C., Gastroenterology and Hepatology, and AGEM - Amsterdam Gastroenterology Endocrinology Metabolism

Subjects
Crohn's disease, anal fistula, consensus, methodology, Gastroenterologi, Gastroenterology, consensu, Gastroenterology and Hepatology
Abstract

Aim: Crohn's anal fistula (CAF) is a complex condition, with no agreement on which patient characteristics should be routinely reported in studies. The aim of this study was to develop a core descriptor set of key patient characteristics for reporting in all CAF research.Method: Candidate descriptors were generated from published literature and stakeholder suggestions. Colorectal surgeons, gastroenterologists and specialist nurses in inflammatory bowel disease took part in three rounds of an international modified Delphi process using nine-point Likert scales to rank the importance of descriptors. Feedback was provided between rounds to allow refinement of the next ratings. Patterns in descriptor voting were assessed using principal component analysis (PCA). Resulting PCA groups were used to organize items in rounds two and three. Consensus descriptors were submitted to a patient panel for feedback. Items meeting predetermined thresholds were included in the final set and ratified at the consensus meeting.Results: One hundred and thirty three respondents from 22 countries completed round one, of whom 67.0% completed round three. Ninety seven descriptors were rated across three rounds in 11 PCA-based groups. Forty descriptors were shortlisted. The consensus meeting ratified a core descriptor set of 37 descriptors within six domains: fistula anatomy, current disease activity and phenotype, risk factors, medical interventions for CAF, surgical interventions for CAF, and patient symptoms and impact on quality of life.Conclusion: The core descriptor set proposed for all future CAF research reflects characteristics important to gastroenterologists and surgeons. This might aid transparent reporting in future studies.

Published
2022

49. DOP001 Effectiveness and safety of vedolizumab in anti-TNF naïve patients with inflammatory bowel disease: a multicentre retrospective European Crohn’s and Colitis Organisation study

Author

Kopylov, U, Verstockt, B, Biedermann, L, Sebastian, S, Pugliese, D, Sonnenberg, E, Steinhagen, P R, Arebi, N, Ron, Y, Kucharzik, T, Roblin, X, Ungar, B, Bar-Gil Shitrit, A, Ardizzone, S, Molander, P, Coletta, M, Peyrin-Biroulet, L, Bossuyt, P, Avni-Biron, I, Tsoukal, E I, Allocca, M, Katsanos, K, Raine, T, Sipponen, T, Fiorino, G, Ben-Horin, S, Eliakim, R, Armuzzi, A, Siegmund, B, Baumgart, D C, Kamperidis, N, Maharshak, N, Maaser, C, Mantzaris, G, Yanai, H, Christodoulou, D, Dotan, I, and Ferrante, M

Published
2018
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