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20 results on '"Komuku, Yuki"'

7. Risk Factors for Legal Blindness in 77 Japanese Patients with Endogenous Endophthalmitis: A Multicenter Cohort Study from J-CREST

Author

Sugisawa, Takaaki, primary, Ishikawa, Hiroto, additional, Uchida, Kazutaka, additional, Takesue, Yoshio, additional, Mori, Junya, additional, Kinoshita, Takamasa, additional, Morikawa, Shohei, additional, Okamoto, Fumiki, additional, Sawada, Tomoko, additional, Ohji, Masahito, additional, Kanda, Takayuki, additional, Takeuchi, Masaru, additional, Miki, Akiko, additional, Kusuhara, Sentaro, additional, Ueda, Tetsuo, additional, Ogata, Nahoko, additional, Sugimoto, Masahiko, additional, Kondo, Mineo, additional, Yoshida, Shigeo, additional, Ogata, Tadahiko, additional, Kimura, Kazuhiro, additional, Mitamura, Yoshinori, additional, Jujo, Tatsuya, additional, Takagi, Hitoshi, additional, Terasaki, Hiroto, additional, Sakamoto, Taiji, additional, Komuku, Yuki, additional, and Gomi, Fumi, additional

Published
2022
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9. Risk factors and characteristics of central serous chorioretinopathy with later development of macular neovascularisation detected on OCT angiography: a retrospective multicentre observational study

Author

Zhou, Xiaoyin, primary, Komuku, Yuki, additional, Araki, Takashi, additional, Terasaki, Hiroto, additional, Miki, Akiko, additional, Kuwayama, Soichiro, additional, Nishi, Tomo, additional, Kinoshita, Takamasa, additional, and Gomi, Fumi, additional

Published
2022
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10. Clinical Characteristics and Outcomes in 314 Japanese Patients with Bacterial Endophthalmitis : A Multicenter Cohort Study from J-CREST

Author

Ishikawa, Hiroto, Uchida, Kazutaka, Takesue, Yoshio, Mori, Junya, Kinoshita, Takamasa, Morikawa, Shohei, Okamoto, Fumiki, Sawada, Tomoko, Ohji, Masahito, Kanda, Takayuki, Takeuchi, Masaru, Miki, Akiko, Kusuhara, Sentaro, Ueda, Tetsuo, Ogata, Nahoko, Sugimoto, Masahiko, Kondo, Mineo, Yoshida, Shigeo, Ogata, Tadahiko, Kimura, Kazuhiro, Mitamura, Yoshinori, Jujo, Tatsuya, Takagi, Hitoshi, Terasaki, Hiroto, Sakamoto, Taiji, Sugisawa, Takaaki, Komuku, Yuki, Gomi, Fumi, Ishikawa, Hiroto, Uchida, Kazutaka, Takesue, Yoshio, Mori, Junya, Kinoshita, Takamasa, Morikawa, Shohei, Okamoto, Fumiki, Sawada, Tomoko, Ohji, Masahito, Kanda, Takayuki, Takeuchi, Masaru, Miki, Akiko, Kusuhara, Sentaro, Ueda, Tetsuo, Ogata, Nahoko, Sugimoto, Masahiko, Kondo, Mineo, Yoshida, Shigeo, Ogata, Tadahiko, Kimura, Kazuhiro, Mitamura, Yoshinori, Jujo, Tatsuya, Takagi, Hitoshi, Terasaki, Hiroto, Sakamoto, Taiji, Sugisawa, Takaaki, Komuku, Yuki, and Gomi, Fumi

Abstract

Bacterial endophthalmitis is an intraocular infection that causes rapid vison loss. Pathogens can infect the intraocular space directly (exogenous endophthalmitis (ExE)) or indirectly (endogenous endophthalmitis (EnE)). To identify predictive factors for the visual prognosis of Japanese patients with bacterial endophthalmitis, we retrospectively examined the bacterial endophthalmitis characteristics of 314 Japanese patients and performed statistics using these clinical data. Older patients, with significantly more severe clinical symptoms, were prevalent in the ExE group compared with the EnE group. However, the final best-corrected visual acuity (BCVA) was not significantly different between the ExE and EnE groups. Bacteria isolated from patients were not associated with age, sex, or presence of eye symptoms. Genus Streptococcus, Streptococcus pneumoniae, and Enterococcus were more prevalent in ExE patients than EnE patients and contributed to poor final BCVA. The presence of eye pain, bacterial identification, and poor BCVA at baseline were risk factors for final visual impairment.

Published
2021

11. Clinical Characteristics and Outcomes in 314 Japanese Patients with Bacterial Endophthalmitis: A Multicenter Cohort Study from J-CREST

Author

Ishikawa, Hiroto, primary, Uchida, Kazutaka, additional, Takesue, Yoshio, additional, Mori, Junya, additional, Kinoshita, Takamasa, additional, Morikawa, Shohei, additional, Okamoto, Fumiki, additional, Sawada, Tomoko, additional, Ohji, Masahito, additional, Kanda, Takayuki, additional, Takeuchi, Masaru, additional, Miki, Akiko, additional, Kusuhara, Sentaro, additional, Ueda, Tetsuo, additional, Ogata, Nahoko, additional, Sugimoto, Masahiko, additional, Kondo, Mineo, additional, Yoshida, Shigeo, additional, Ogata, Tadahiko, additional, Kimura, Kazuhiro, additional, Mitamura, Yoshinori, additional, Jujo, Tatsuya, additional, Takagi, Hitoshi, additional, Terasaki, Hiroto, additional, Sakamoto, Taiji, additional, Sugisawa, Takaaki, additional, Komuku, Yuki, additional, and Gomi, Fumi, additional

Published
2021
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17. ASSOCIATION OF FLOW SIGNALS WITHIN POLYPS ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY WITH TREATMENT RESPONSES AFTER COMBINATION THERAPY FOR POLYPOIDAL CHOROIDAL VASCULOPATHY

Author

Fukuyama, Hisashi, Komuku, Yuki, Araki, Takashi, and Gomi, Fumi

Abstract

This study retrospective case series of 46 eyes who underwent combination therapy of photodynamic therapy and anti–vascular endothelial growth factor injection for polypoidal choroidal vasculopathy. OCT-angiography makes it possible to detect polypoidal lesions noninvasively, and flow signal in polyps could be a biomarker for early recurrence or poor response.

Published
2022
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18. Flanged intraocular lens fixation via 27‐gauge trocars using a double‐needle technique decreases surgical wounds without losing its therapeutic effect.

Author

Ishikawa, Hiroto, Fukuyama, Hisashi, Komuku, Yuki, Araki, Takashi, and Gomi, Fumi

Subjects
SURGICAL site, INTRAOCULAR lenses, TREATMENT effectiveness, OPERATIVE surgery, VITRECTOMY, VISUAL acuity
Abstract

Purpose: Intraocular lens (IOL) fixation using a sutureless 27‐gauge needle intrascleral IOL implantation technique requires six surgical wounds. We developed a modified technique using two 27‐gauge trocars for vitrectomy and indwelling flanged IOL haptics to reduce the number of surgical wounds. Setting: Department of Ophthalmology, Hyogo College of Medicine. Design: This retrospective study enrolled 54 patients who had undergone IOL scleral fixation between January 2016 and April 2019. Methods: Patients who underwent IOL scleral fixation and were observed for >12 weeks were analysed using medical record data. Before October 2017, patients underwent normal flanged IOL scleral fixation. Between November 2017 and April 2019, patients underwent the modified method (flanged IOL via 27‐gauge trocars with double‐needle technique). Primary end‐point was superiority or non‐inferiority of modified IOL scleral fixation compared with normal IOL scleral fixation for visual acuity (VA). Changes in corneal endothelium cell number, refractivity, astigmatisms and surgery‐related complications, were secondary end‐points. Results: There were no significant differences in baseline characteristics between groups. Raw VA and best collected VA (BCVA) were significantly improved in all eyes (p−). There were no statistical significances in raw VA, BCVA and surgery‐related complications between groups. Conclusions: Results of the modified technique were not inferior compared with the original technique although it was less invasive. Therefore, flanged IOL fixation via trocars using a double‐needle technique is a useful technique for IOL implantation. [ABSTRACT FROM AUTHOR]

Published
2020
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20. Risk Factors for Legal Blindness in 77 Japanese Patients with Endogenous Endophthalmitis: A Multicenter Cohort Study from J-CREST.

Author

Sugisawa T, Ishikawa H, Uchida K, Takesue Y, Mori J, Kinoshita T, Morikawa S, Okamoto F, Sawada T, Ohji M, Kanda T, Takeuchi M, Miki A, Kusuhara S, Ueda T, Ogata N, Sugimoto M, Kondo M, Yoshida S, Ogata T, Kimura K, Mitamura Y, Jujo T, Takagi H, Terasaki H, Sakamoto T, Komuku Y, and Gomi F

Subjects
Humans, Blindness prevention & control, Cohort Studies, East Asian People, Retrospective Studies, Risk Factors, Visual Acuity, Endophthalmitis microbiology, Eye Infections, Bacterial microbiology
Abstract

Purpose: We investigated potential predictive factors for visual prognosis in Japanese patients with endogenous endophthalmitis., Design: Retrospective observational multicenter cohort study., Methods: We examined the characteristics of 77 Japanese patients with endogenous endophthalmitis and performed statistical analyses of these real-world data. The primary endpoint was the identification of factors associated with visual prognosis. We examined differences between patients in the better vision and legal blindness groups at 12 weeks after treatment initiation., Results: The five risk factors for visual impairment at 12 weeks after treatment initiation were presence of pressure injuries, severe clinical symptoms (presence of eye pain and ciliary injection), pathogen identification, and poor best-corrected visual acuity at baseline. Staphylococcus aureus and fungus were associated with a better visual impairment outcome., Conclusions: Endogenous endophthalmitis remains a severe ocular infection; however, it can be managed with rapid treatments, as well as other advances in medical knowledge and technology.

Published
2023
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