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Businesses increasingly aim to attract new employees and customers by creating a unique brand identity. Airlines, particularly low-cost carriers, are no exception. After the staff shortages caused by the COVID-19 pandemic, airlines use branding to regain their competitive edge and restore customer satisfaction. This paper explores the role of employer branding, a fusion of human resources and marketing, in the aviation sector. The research integrates both consumer and employee perspectives, helping to deepen the understanding of how a strong employer brand drives organizational success. It contributes to existing literature by addressing the gap in studies examining the interplay between these factors. A literature review and qualitative analysis of seventeen case studies, meeting three selected parameters (year, topic, and data used), were conducted to achieve the research goals. Results show that service performance and credibility are critical factors in aviation, more so than in other industries. To build customer loyalty, airlines should focus on meeting diverse needs based on travel types, offering memorable experiences, and ensuring website security. By strengthening their brand, companies can enhance their attractiveness to job seekers, boost employee and customer satisfaction and loyalty, and improve overall business performance.

The integration of logistics and information systems in urban waste management is a key step towards building sustainable smart cities. In the context of increasing urbanisation and environmental challenges, cities are forced to look for more efficient solutions for waste management. This paper explores how the interconnection of logistics and modern information technology can optimize waste collection, sorting and recycling processes, reduce operational costs and minimize negative environmental impacts. Using smart sensors, monitoring systems and analytical tools, it is possible to improve the planning of waste collection routes and predict the needs of different areas. The result is greater efficiency in urban waste management, leading to reduced landfill waste production and better use of recyclable materials. This article also highlights the need for coordinated cooperation between the public and private sectors, as well as the importance of a legislative framework that promotes technological innovation and environmental sustainability. Integrating these solutions into the infrastructure of modern cities contributes to their transition towards sustainable and smart urban ecosystems.

This article aims to provide an overview of the current state of research on artificial intelligence in logistics, focusing on identifying key thematic areas addressed by the authors in this field. The article analyzes specific thematic areas that are the subject of individual studies dealing with this issue. Various methodological approaches were used in the analysis, including bibliometric analysis aimed at mapping the development of research and identifying key publications in the field of artificial intelligence in logistics. The PRISMA method was applied to select relevant sources, while qualitative content analysis was used for an in-depth evaluation of the studies’ content and for identifying the most frequently covered theoretical areas. The results show that research on artificial intelligence in logistics focuses on diverse thematic areas, such as digital transformation, sustainability and environmental aspects, process optimization within supply chains, and human-machine interaction. This article provides valuable insights for experts and practitioners in the field of logistics and serves as a foundation for further research in this dynamically evolving area.

This study aims to evaluate exam questions set by science teachers for eighth grade students and science questions from a central high school entrance exam (HSEE) according to the Revised Bloom's Taxonomy (RBT). In this study, document analysis technique was employed, as one of the recognized methods of qualitative research. The HSEE science questions and the teacher-prepared exam questions were evaluated separately in the dimensions of knowledge and cognitive process, and the frequency and percentage distribution of the questions were examined according to the RBT. The science teachers' exam questions were found to be the most suitable for factual knowledge in the RBT knowledge dimension, and the most appropriate for the remembering and understanding levels of the cognitive process dimension. It was determined that the HSEE science questions were the most suitable for conceptual and procedural types of knowledge in the RBT knowledge dimension, and for the understanding and analyzing levels in the cognitive process dimension. Both the questions prepared by teachers and the HSEE science questions were not homogeneously distributed in terms of the RBT. It was determined that while the science teachers' exam questions were at the lower level of the cognitive process, the HSEE science questions were at a level higher than those prepared by the teachers.

The principles of management control and coordination of management control are described in Section I, Chapter 6 - Articles 68 - 71 of the Act of August 27, 2009 on Public Finance. Detailed rules on the manner of preparation and specimens of documents required by the provisions of the aforementioned Act are established in the Decree of the Minister of Finance of September 29, 2010 on the activity plan and the report on its implementation, and in the Decree of the Minister of Finance of December 2, 2010 on the model statement on the state of management control. Requirements relating to the establishment, evaluation and improvement of management control systems for the public finance sector are specified in Announcement No. 23 of the Minister of Finance dated December 16, 2009 on management control standards for the public finance sector. Guidance on monitoring and evaluating the adequacy, effectiveness and efficiency of management control is provided in Announcement No. 3 of the Minister of Finance dated February 16, 2011 on detailed guidelines for self-evaluation of management control for units in the public finance sector. The guidelines supporting effective risk management in units of the public finance sector are announced in Announcement No. 6 of the Minister of Finance of December 6, 2012 on detailed guidelines for the public finance sector on planning and risk management. The article analyzes the legal regulations of Articles

The principles of employing Police officers are regulated by the Act of April 6, 1990 on the Police, professional pragmatics of an autonomous nature. In the discussed pragmatics, the legislator divided the exhaustive catalog of reasons for dismissal from service into two reasons - obligatory and optional. The impetus for undertaking the research issues covered in this article was the construction of one of the reasons for optional dismissal from service. Namely, in accordance with Art. 41 section 2 point 5 of the Police Act, a police officer may be dismissed from service when an important interest of the service requires it. The construction of the service's interest is nothing more than the normative construction of a general clause, which by its nature is unspecified. Therefore, the closed catalog of grounds for dismissal from service remains open in this respect. The legislator deliberately and consciously uses this construction to make the generally closed catalog of reasons for dismissal from service more flexible. It should be stated, however, that although the Police authority is provided with a large area of freedom in the process of applying the law, the clause in question is not the basis for the authority to make arbitrary and instrumental assessments. The service interest clause, despite its undefined nature, refers to extra-legal criteria with a semantic context defined by the name of the criterion.

Tax proceedings are a separate type of administrative proceeding, which is conducted by tax authorities. It has the character of an authoritative, public-law concretization, a unilateral legal relationship in the field of tax law. The provisions governing the proceeding include both the Tax Ordinance and the Code of Administrative Procedure. The purpose of tax proceedings is to assess tax... Administrative proceedings are both a series of procedural actions, regulated by procedural law, taken by public administration bodies and other procedural entities to resolve an administrative matter in the form of an administrative decision, and a series of procedural actions taken to verify a previously issued administrative decision. Administrative procedure, also called formal administrative law, procedural administrative law or administrative procedure, is one of the three parts of administrative law.

Confined fluids and electrolyte solutions in nanopores exhibit rich and surprising physics and chemistry that impact the mass transport and energy efficiency in many important natural systems and industrial applications. Existing theories often fail to predict the exotic effects observed in the narrowest of such pores, called single-digit nanopores (SDNs), which have diameters or conduit widths of less than 10 nm, and have only recently become accessible for experimental measurements. What SDNs reveal has been surprising, including a rapidly increasing number of examples such as extraordinarily fast water transport, distorted fluid-phase boundaries, strong ion-correlation and quantum effects, and dielectric anomalies that are not observed in larger pores. Exploiting these effects presents myriad opportunities in both basic and applied research that stand to impact a host of new technologies at the water-energy nexus, from new membranes for precise separations and water purification to new gas permeable materials for water electrolyzers and energy-storage devices. SDNs also present unique opportunities to achieve ultrasensitive and selective chemical sensing at the single-ion and single-molecule limit. In this review article, we summarize the progress on nanofluidics of SDNs, with a focus on the confinement effects that arise in these extremely narrow nanopores. The recent development of precision model systems, transformative experimental tools, and multiscale theories that have played enabling roles in advancing this frontier are reviewed. We also identify new knowledge gaps in our understanding of nanofluidic transport and provide an outlook for the future challenges and opportunities at this rapidly advancing frontier.

The manufacture and production of industrial chemicals continues to increase, with hundreds of thousands of chemicals and chemical mixtures used worldwide, leading to widespread population exposures and resultant health impacts. Low-wealth communities and communities of color often bear disproportionate burdens of exposure and impact; all compounded by regulatory delays to the detriment of public health. Multiple authoritative bodies and scientific consensus groups have called for actions to prevent harmful exposures via improved policy approaches. We worked across multiple disciplines to develop consensus recommendations for health-protective, scientific approaches to reduce harmful chemical exposures, which can be applied to current US policies governing industrial chemicals and environmental pollutants. This consensus identifies five principles and scientific recommendations for improving how agencies like the US Environmental Protection Agency (EPA) approach and conduct hazard and risk assessment and risk management analyses: (1) the financial burden of data generation for any given chemical on (or to be introduced to) the market should be on the chemical producers that benefit from their production and use; (2) lack of data does not equate to lack of hazard, exposure, or risk; (3) populations at greater risk, including those that are more susceptible or more highly exposed, must be better identified and protected to account for their real-world risks; (4) hazard and risk assessments should not assume existence of a "safe" or "no-risk" level of chemical exposure in the diverse general population; and (5) hazard and risk assessments must evaluate and account for financial conflicts of interest in the body of evidence. While many of these recommendations focus specifically on the EPA, they are general principles for environmental health that could be adopted by any agency or entity engaged in exposure, hazard, and risk assessment. We also detail recommendations for four priority areas in companion papers (exposure assessment methods, human variability assessment, methods for quantifying non-cancer health outcomes, and a framework for defining chemical classes). These recommendations constitute key steps for improved evidence-based environmental health decision-making and public health protection.

A key element of risk assessment is accounting for the full range of variability in response to environmental exposures. Default dose-response methods typically assume a 10-fold difference in response to chemical exposures between average (healthy) and susceptible humans, despite evidence of wider variability. Experts and authoritative bodies support using advanced techniques to better account for human variability due to factors such as in utero or early life exposure and exposure to multiple environmental, social, and economic stressors.This review describes: 1) sources of human variability and susceptibility in dose-response assessment, 2) existing US frameworks for addressing response variability in risk assessment; 3) key scientific inadequacies necessitating updated methods; 4) improved approaches and opportunities for better use of science; and 5) specific and quantitative recommendations to address evidence and policy needs.Current default adjustment factors do not sufficiently capture human variability in dose-response and thus are inadequate to protect the entire population. Susceptible groups are not appropriately protected under current regulatory guidelines. Emerging tools and data sources that better account for human variability and susceptibility include probabilistic methods, genetically diverse in vivo and in vitro models, and the use of human data to capture underlying risk and/or assess combined effects from chemical and non-chemical stressors.We recommend using updated methods and data to improve consideration of human variability and susceptibility in risk assessment, including the use of increased default human variability factors and separate adjustment factors for capturing age/life stage of development and exposure to multiple chemical and non-chemical stressors. Updated methods would result in greater transparency and protection for susceptible groups, including children, infants, people who are pregnant or nursing, people with disabilities, and those burdened by additional environmental exposures and/or social factors such as poverty and racism.

Introduction: Sodium-glucose cotransporter-2 inhibitors (SGLT2 inhibitors), known as flozins, are a recent class of medications gaining recognition for their effectiveness in diabetes, cardiovascular health, and heart failure management. The objective of this study is to examine and integrate recent literature concerning the mechanisms, effectiveness, and safety of SGLT2 inhibitors in managing heart failure. Material and Methods of Research: A literature review focused on keywords related to the topic was performed using databases such as PubMed and Google Scholar. Results: SGLT-2 inhibitors, initially developed for type 2 diabetes, significantly benefit heart failure (HF) with reduced, mildly reduced, and preserved ejection fractions by improving various cardiac outcomes. These drugs lower glucose levels and promote osmotic diuresis, natriuresis, and favorable metabolic effects, reducing cardiac preload and afterload. Consequently, SGLT-2 inhibitors are now pivotal in HF treatment, enhancing cardiac efficiency and reducing HF-related hospitalizations and mortality. Conclusion: SGLT-2 inhibitors substantially decrease cardiovascular risk and hospitalizations for heart failure in patients with or without type 2 diabetes, making them crucial in HF management. Consequently, SGLT-2 inhibitors should be considered first-line therapy for heart failure, regardless of concurrent medications, due to their efficacy and comprehensive benefits in managing this condition.

Introduction: Ozempic is a new generation antihyperglycemic drug used to treat type 2 diabetes in adults whose underlying disease is not sufficiently controlled with physical activity and diet, as well as for long-term weight control in people with excess body weight and comorbidities. The aim of this study is to explore and integrate the latest literature on the analysis of the pharmacology, mechanism of action and clinical applications of Ozempic. Material and Methods of Research: A literature review focused on keywords related to the topic was performed using databases such as PubMed and Google Scholar. Results: Ozempic effectively lowers blood glucose levels and supports weight loss in patients with type 2 diabetes and obesity. Clinical trials have demonstrated its superiority over other antidiabetic medications, with significant reductions in HbA1c and body weight. Patients receiving Ozempic experienced improved glycemic control and cardiovascular outcomes, with manageable side effects. Ongoing research suggests additional benefits in cardiovascular prevention and obesity management. Conclusion: Ozempic (semaglutide) is a potent GLP-1 receptor agonist that effectively improves glycemic control and aids in weight reduction for patients with type 2 diabetes and obesity. Its practical administration, patient education, and regular monitoring are essential for optimal outcomes. Ongoing research and technological advancements, including the development of oral forms, promise to expand its applications and improve patient adherence, making Ozempic a versatile and valuable therapeutic option.

Exposures to industrial chemicals are widespread and can increase the risk of adverse health effects such as cancer, developmental disorders, respiratory effects, diabetes, and reproductive problems. The amended Toxic Substances Control Act (amended TSCA) requires the U.S. Environmental Protection Agency (EPA) to evaluate risks of chemicals in commerce, account for risk to potentially exposed and susceptible populations, and mitigate risks for chemicals determined to pose an unreasonable risk to human health and the environment. This analysis compares EPA's first 10 chemical risk evaluations under amended TSCA to best scientific practices for conducting risk assessments. We find EPA's risk evaluations underestimated human health risks of chemical exposures by excluding conditions of use and exposure pathways; not considering aggregate exposure and cumulative risk; not identifying all potentially exposed or susceptible subpopulations, and not quantifying differences in risk for susceptible groups; not addressing data gaps; and using flawed systematic review approaches to identify and evaluate the relevant evidence. We present specific recommendations for improving the implementation of amended TSCA using the best available science to ensure equitable, socially just safeguards to public health. Failing to remedy these shortcomings will result in continued systematic underestimation of risk for all chemicals evaluated under amended TSCA.

Ocean currents play an important role in regulating the Earth's climate by redistributing ocean heat around the planet. One important climate phenomenon that includes several large ocean currents is the Atlantic Meridional Overturning Circulation, which is the process of warm surface currents in the North Atlantic Ocean moving to the Arctic to ultimately form cold currents near the seafloor. This process relieves the tropics of excess ocean heat, which helps reduce the intensity of Atlantic hurricanes. Scientists are concerned that the Atlantic Meridional Overturning Circulation may slow, or even collapse, because of anthropogenic climate change. In this activity, students will use selected portions of a four-year dataset of observations of the Atlantic Meridional Overturning Circulation to learn about the importance of long-term consistent sampling and data biases. The students will plot their data, calculate the slope between the first and last points, listen to sonified versions of the data, and discuss trends in the data. This activity will also give students the opportunity to build a mooring with craft supplies representing the anchor, cable, scientific instruments, and flotation. There are modifications for the visually impaired via the graphing format, data sonification, and with the tactile nature of the mooring construction.

The article’s primary purpose is to highlight the importance of cybersecurity for Internet of Things (IoT) devices. Due to the widespread use of such devices in everyone’s daily and professional lives, taking care of their security is essential. This security can be strengthened by raising awareness about the vulnerabilities and risks of these devices among their manufacturers and users. Therefore, this paper shows the results of several years of work regarding building vulnerabilities and exploiting databases, with a particular focus on IoT devices. We highlight multiple unique features of our solution, such as aggregation, correlation, and enrichment of known vulnerabilities and exploits collected from 12 different sources, presentation of a timeline of threats, and combining vulnerability information with exploits. Our databases have more than 300,000 entries, which are the result of aggregating and correlating more than 1,300,000 entries from 12 different databases simultaneously, enriched with information from unstructured sources. We cover the innovative utilization of Artificial Intelligence (AI) to support data enrichment, examining the usage of the Light Gradient-Boosting Machine (LGBM) model to automatically predict vulnerability severity and Mistral7B to categorize vulnerable products, which, especially in the case of IoT devices, is critical due to the diversity of nomenclature. Social media and various unstructured sources are prominent places for gathering information. Retrieving data from them is much more complex than from structured databases, but the information there is normally supplied at a faster rate. Thus, we added Mastodon monitoring to enhance our threat timelines.

Indonesia needs bathymetry information for diverse applications as a maritime country. There are various methods of determining the water depth for bathymetry. The advancement of satellite imagery data has led to the increasing use of remote sensing data for depth measurements. With satellite imaging, wide area coverage can be achieved in a relatively short time, making depth data acquisition more cost-effective. SAR (Synthetic Aperture Radar) imagery is an active remote sensing technology developed to estimate depth data known as the SAR Bathymetry method. This method is still not widely applied, especially in Indonesia, even though it has considerable potential with cloud-free imageries, where it becomes a severe problem in tropical countries when using optical imagery. Therefore, this paper will discuss algorithms and techniques for depth data estimation using SAR Bathymetry and their possible implementation in Indonesia. The optimum depth, SAR image recommendation, and conditions required to apply this method will also be discussed.

Introduction: Engaging in regular aerobic exercise can have a tremendous impact on one's physical and mental well-being. Despite the known benefits, a significant number of adults worldwide continue to lead sedentary lifestyles. Aerobic exercise, in particular, has been shown to improve lipid profiles, reducing the risk of cardiovascular diseases and mortality rates. Additionally, it promotes healthy metabolism, hormonal balance, and mental well-being, all of which contribute to overall health and quality of life. This is especially crucial for cancer patients undergoing treatment. Aim of the Study: The primary objective of this study is to conduct a comprehensive analysis of the physiological and psychological benefits of aerobic exercise on the human body. Description of the State of Knowledge: Moderate and regular aerobic exercise has been shown to have a beneficial effect on both physical and mental health. The importance of improving physical performance, overall body fitness, endurance, strength, balance, and mobility cannot be overstated, as it has a proven therapeutic and preventive effect against various diseases. Materials and methods: An unsystematic scientific literature review was conducted using specific keywords such as earobic exercise, lipid profile, cardiovascular system, cardiovascular disease, diabetes. The review was carried out on PubMed, analyzing a total of 70 sources published until 2023. Conclusions: Exercise has beneficial effects on all organ systems and is a non-pharmacological form of treatment for cardiovascular, musculoskeletal, metabolic and nervous system diseases. They have the benefits of reducing stress, lowering blood pressure, stimulating osteogenesis, and having a beneficial effect on body shape and self-perception. Exercise can be considered an effective treatment for established diseases or the alleviation of their symptoms.

Introduction. Childhood infectious diseases have been a significant medical problem, with a global increase in recent years. Modern diagnostic methods and new vaccinations are available. Poland is part of the WHO-coordinated global measles and rubella elimination program. Controversy surrounds mandatory and recommended vaccinations in Poland. There has been a concerning increase in the abandonment of vaccinating children, leading to a resurgence of infectious diseases. In 2024, the WHO reported a significant increase in measles cases in the European region, including in Poland. It's crucial to remind people of these diseases and warn them about the complications they bring. Aim of study. The aim of this study is to investigate the increasing occurrence of infectious diseases in childhood and examine the correlation with declining vaccination rates across society. Materials and methods. An unsystematic review of scientific literature was conducted, employing specific keywords such as „measles,” „pertussis,” „rubella,” „infectious diseases,” „vaccination,” and „hib.” The review was executed on the PubMed database, analyzing a total of 59 sources published until the conclusion of 2024. Conclusions. To control and eliminate infectious diseases, it is vital to maintain and improve vaccination rates. Policymakers and healthcare providers should prioritize immunization programs and address barriers to vaccine access. Further research is crucial to develop comprehensive strategies for increasing vaccination coverage and understanding vaccine-preventable diseases in modern public health challenges.

IntroductionResidents of long-term care facilities (LTCFs) are at high risk of morbidity and mortality due to COVID-19, especially when new variants of concern (VOC) emerge. To provide intradisciplinary data in order to tailor public health interventions during future epidemics, available epidemiologic and genomic data from Slovenian LTCFs during the initial phases of the COVID-19 pandemic was analyzed.MethodsThe first part of the study included SARS-CoV-2 reverse-transcription Real-Time PCR (rtRT-PCR) positive LTCF residents, from 21 facilities with COVID-19 outbreaks occurring in October 2020. The second part of the study included SARS-CoV-2 rtRT-PCR positive LTCF residents and staff between January and April 2021, when VOC Alpha emerged in Slovenia. Next-generation sequencing (NGS) was used to acquire SARS-CoV-2 genomes, and lineage determination. In-depth phylogenetic and mutational profile analysis were performed and coupled with available field epidemiological data to assess the dynamics of SARS-CoV-2 introduction and transmission.Results370/498 SARS-CoV-2 positive residents as well as 558/699 SARS-CoV-2 positive residents and 301/358 staff were successfully sequenced in the first and second part of the study, respectively. In October 2020, COVID-19 outbreaks in the 21 LTCFs were caused by intra-facility transmission as well as multiple independent SARS-CoV-2 introductions. The Alpha variant was confirmed in the first LTCF resident approximately 1.5 months after the first Alpha case was identified in Slovenia. The data also showed a slower replacement of existing variants by Alpha in residents compared to staff and the general population.DiscussionMultiple SARS CoV-2 introductions as well as intra-facility spreading impacted disease transmission in Slovenian LTCFs. Timely implementation of control measures aimed at limiting new introductions while controlling in-facility transmission are of paramount importance, especially as new VOCs emerge. Sequencing, in conjunction with epidemiological data, can facilitate the determination of the need for future improvements in control measures to protect LTCF residents from COVID-19 or other respiratory infections.

Introduction: Hashimoto's thyroiditis is a prevalent autoimmune disease among the population. With the progress in diagnostic and research techniques, it has come to light that Hashimoto's thyroiditis is linked to a higher likelihood of developing other disorders that impact multiple organs and systems. Throughout the course of this disease, individuals may experience an array of complications such as sexual dysfunctions, fertility problems, specific mental disorders, cardiovascular diseases and other autoimmune diseases. Aim of the Study: The primary aim of this study is to explore the potential association between Hashimoto’s thyroiditis and its consequential effects on other physiological systems and organs. Description of the State of Knowledge: Hashimoto's thyroiditis is a complex autoimmune disease characterized by chronic inflammation of the thyroid gland. The pathogenesis of the disease is not yet completely understood. Hashimoto's thyroiditis has been associated with a range of health issues, including sexual dysfunction, fertility problems, psychiatric disorders, cardiovascular diseases, and other autoimmune disorders. Materials and methods: An unsystematic scientific literature review was conducted using specific keywords such as Hashimoto's thyroiditis, fertility problems, thyroid tumor, cardiovascular diseases, and autoimmune diseases. The review was carried out on PubMed, analyzing a total of 53 sources published until 2023. Conclusions: HT's association with psychiatric disorders, fertility issues, thyroid tumors, cardiovascular dysfunction, and comorbid autoimmune conditions underscores its broad clinical impact, necessitating integrated management approaches. Effective management of HT requires collaboration among specialists to ensure early detection, proactive intervention, and patient education, ultimately improving therapeutic outcomes and quality of life.

Employee recruitment is among the most critical processes performed in businesses. Nowadays, it is more and more frequently implemented online. Companies switch to e-recruitment, utilising information and communication technologies (ICT). This article aims to identify the risks emerging while implementing such a solution and set the risk management steps to sustain the business’s long-term operation. The analysis is based on secondary as well as primary data. Multiple methods were applied: observation, questionnaire survey, semi-structured interviews, case study analysis, comparison, and synthesis. The authors’ original case study was created to reduce employee turnover via a new approach to the recruitment process. Research questions and hypotheses focus on examining the relationship between the length of the employee’s employment and how they were approached in the recruitment process. The main findings include identifying key potential risks jeopardising the implementation of e-recruitment. The analysis concluded that no employee recruitment step in the selected business is performed online. The practical result of this research included the creation of the business’s career website. This can inform the potential applicants about the business’s activities. It was created to support individual activities of the employee recruitment process. Finally, recommendations were designed for the managers of other companies. They can use these in implementing ICT solutions for the recruitment process to support long-term sustainability.

This study proposed a practical seismic retrofit method for RC frames. For this purpose, a quasi-static loading was applied to 8 RC frames in finite element analysis software, Abaqus, and frames were pushed 45 mm laterally. High-strength fiber-reinforced lightweight concrete panels strengthened infill walls inside the RC frames. To apply them to the walls, epoxy binder and polyurethane binder were used, and their behavior was compared. Using panels increased the lateral load capacity of the whole frame according to the numerical analysis performed with Abaqus. In the worst case, the retrofitted frame carried approximately two times the traditionally infilled frame's capacity. In the best case, the RC frame carried 4.29 times the lateral load traditionally infilled frame. Polyurethane binder prevented the separation of panels from walls and provided a ductile behavior to frames even in large drifts.

The current business environment faces numerous new challenges closely linked to the rapid development of information and communication technologies, which influence the corporate landscape. This article focuses on exploring the possibilities of integrating artificial intelligence, as one of the key technologies of today, into the recruitment process. Its aim is to examine the potential applications of artificial intelligence across various stages of employee recruitment. To achieve this goal, the authors employed various methods and techniques, including the PICOS framework, scientific mapping, and case study analysis. The outcome of this study identifies opportunities for leveraging artificial intelligence in the employee recruitment process within corporate settings. The results reflect the current research gaps concerning the analysis of the personnel processes and conceptualizing the implementation possibilities of artificial intelligence in these processes. The contribution of this article to the academic community lies in its conceptualization, providing a foundation for further research focused on analyzing the impacts of integrating AI into recruitment processes.

Abstract A key element of risk assessment is accounting for the full range of variability in response to environmental exposures. Default dose-response methods typically assume a 10-fold difference in response to chemical exposures between average (healthy) and susceptible humans, despite evidence of wider variability. Experts and authoritative bodies support using advanced techniques to better account for human variability due to factors such as in utero or early life exposure and exposure to multiple environmental, social, and economic stressors. This review describes: 1) sources of human variability and susceptibility in dose-response assessment, 2) existing US frameworks for addressing response variability in risk assessment; 3) key scientific inadequacies necessitating updated methods; 4) improved approaches and opportunities for better use of science; and 5) specific and quantitative recommendations to address evidence and policy needs. Current default adjustment factors do not sufficiently capture human variability in dose-response and thus are inadequate to protect the entire population. Susceptible groups are not appropriately protected under current regulatory guidelines. Emerging tools and data sources that better account for human variability and susceptibility include probabilistic methods, genetically diverse in vivo and in vitro models, and the use of human data to capture underlying risk and/or assess combined effects from chemical and non-chemical stressors. We recommend using updated methods and data to improve consideration of human variability and susceptibility in risk assessment, including the use of increased default human variability factors and separate adjustment factors for capturing age/life stage of development and exposure to multiple chemical and non-chemical stressors. Updated methods would result in greater transparency and protection for susceptible groups, including children, infants, people who are pregnant or nursing, people with disabilities, and those burdened by additional environmental exposures and/or social factors such as poverty and racism.

Abstract The manufacture and production of industrial chemicals continues to increase, with hundreds of thousands of chemicals and chemical mixtures used worldwide, leading to widespread population exposures and resultant health impacts. Low-wealth communities and communities of color often bear disproportionate burdens of exposure and impact; all compounded by regulatory delays to the detriment of public health. Multiple authoritative bodies and scientific consensus groups have called for actions to prevent harmful exposures via improved policy approaches. We worked across multiple disciplines to develop consensus recommendations for health-protective, scientific approaches to reduce harmful chemical exposures, which can be applied to current US policies governing industrial chemicals and environmental pollutants. This consensus identifies five principles and scientific recommendations for improving how agencies like the US Environmental Protection Agency (EPA) approach and conduct hazard and risk assessment and risk management analyses: (1) the financial burden of data generation for any given chemical on (or to be introduced to) the market should be on the chemical producers that benefit from their production and use; (2) lack of data does not equate to lack of hazard, exposure, or risk; (3) populations at greater risk, including those that are more susceptible or more highly exposed, must be better identified and protected to account for their real-world risks; (4) hazard and risk assessments should not assume existence of a “safe” or “no-risk” level of chemical exposure in the diverse general population; and (5) hazard and risk assessments must evaluate and account for financial conflicts of interest in the body of evidence. While many of these recommendations focus specifically on the EPA, they are general principles for environmental health that could be adopted by any agency or entity engaged in exposure, hazard, and risk assessment. We also detail recommendations for four priority areas in companion papers (exposure assessment methods, human variability assessment, methods for quantifying non-cancer health outcomes, and a framework for defining chemical classes). These recommendations constitute key steps for improved evidence-based environmental health decision-making and public health protection.

Zaradi težnje po prepovedi kirurške kastracije merjascev, se razmišlja o alternativah, ki vključujejo tudi pitanje merjascev za prirejo mesa. Problem pri porabi merjaščevega mesa predstavlja predvsem neprijeten vonj, za katerega je v veliki meri odgovoren skatol (3-metilindol). V raziskavi smo vpeljali spektrofotometrično metodo za določanje vsebnosti skatola v maščobnem tkivu. Zbrali smo vzorce petih genotipv merjascev iz petih različnih rej, starih med 101 in 310 dni. Ob vpeljavi metode smo analizirali prvo skupino, kasneje dobljene vzorce pa kot drugo skupino. Vpeljana metoda je ponovljiva (koeficient variabilnosti, KV = 13,6), obnovljiva (KV = 21,3) in ima dober izkoristek (96 %). Vsebnost skatola v hrbtnem maščobnem tkivu merjascev pri prvi skupini je bila mes 0,01 in 0,62 ppm, v povprečju 0,23 ppm. Druga skupina pa je v povprečju vsebovala 0,71 ppm skatola (med 0,07 in 1,26 ppm). Vpliva genotipa, rejca in starosti na vsebnost skatola nismo zaznali.

The 2016 Frank Lautenberg Chemical Safety for the 21st Century Act (Lautenberg TSCA) amended the 1976 Toxic Substances Control Act (TSCA) to mandate protection of susceptible and highly exposed populations. Program implementation entails a myriad of choices that can lead to different degrees of public health protections. Well-documented exposures to multiple industrial chemicals occur from air, soil, water, food, and products in our workplaces, schools, and homes. Many hazardous chemicals are associated with or known to cause health risks; for other industrial chemicals, no data exist to confirm their safety because of flaws in 1976 TSCA. Under the 2016 Lautenberg amendments, the United States Environmental Protection Agency (EPA) must evaluate chemicals against risk-based safety standards under enforceable deadlines, with an explicit mandate to identify and assess risks to susceptible and highly exposed populations. Effective public health protection requires EPA to implement the Lautenberg TSCA requirements by incorporating intrinsic and extrinsic factors that affect susceptibility, adequately assessing exposure among vulnerable groups, and accurately identifying highly exposed groups. We recommend key scientific and risk assessment principles to inform health-protective chemical policy such as consideration of aggregate exposures from all pathways and, when data are lacking, the use of health-protective defaults.

A widely utilized tool in reactor analysis is passive tracers that report the residence time distribution, allowing estimation of the conversion and other properties of the system. Recently, advances in microrobotics have introduced powered and functional entities with sizes comparable to some traditional tracers. This has motivated the concept of Smart Tracers that could record the local chemical concentrations, temperature, or other conditions as they progress through reactors. Herein, the design constraints and advantages of Smart Tracers by simulating their operation in a laminar flow reactor model conducting chemical reactions of various orders are analyzed. It is noted that far fewer particles are necessary to completely map even the most complex concentration gradients compared with their conventional counterparts. Design criteria explored herein include sampling frequency, memory storage capacity, and ensemble number necessary to achieve the required accuracy to inform a reactor model. Cases of severe particle diffusion and sensor noise appear to bind the functional upper limit of such probes and require consideration for future design. The results of the study provide a starting framework for applying the new technology of microrobotics to the broad and impactful set of problems classified as chemical reactor analysis.

Rationale: The endocannabinoid system is known to be involved in learning, memory, emotional processing and regulation of personality patterns. Here we assessed the endocannabinoid profile in the brains of mice with strong characteristics of social dominance and submissiveness.Methods: A lipidomics approach was employed to assess the endocannabinoidome in the brains of Dominant (Dom) and Submissive (Sub) mice. The endocannabinoid showing the greatest difference in concentration in the brain between the groups, docosatetraenoyl ethanolamine (DEA), was synthesized, and its effects on the physiological and behavioral responses of Dom and Sub mice were evaluated. mRNA expression of the endocannabinoid receptors and enzymes involved in PUFA biosynthesis was assessed using qRT-PCR.Results: Targeted LC/MS analysis revealed that long-chain polyunsaturated ethanolamides including arachidonoyl ethanolamide (AEA), DEA, docosatrienoyl ethanolamide (DTEA), eicosatrienoyl ethanolamide (ETEA), eicosapentaenoyl ethanolamide (EPEA) and docosahexaenoyl ethanolamide (DHEA) were higher in the Sub compared with the Dom mice. Untargeted LC/MS analysis showed that the parent fatty acids, docosatetraenoic (DA) and eicosapentaenoic (EPA), were higher in Sub vs. Dom. Gene expression analysis revealed increased mRNA expression of genes encoding the desaturase FADS2 and the elongase ELOVL5 in Sub mice compared with Dom mice. Acute DEA administration at the dose of 15 mg/kg produced antinociceptive and locomotion-inducing effects in Sub mice, but not in Dom mice. Subchronic treatment with DEA at the dose of 5 mg/kg augmented dominant behavior in wild-type ICR and Dom mice but not in Sub mice.Conclusion: This study suggests that the endocannabinoid system may play a role in the regulation of dominance and submissiveness, functional elements of social behavior and personality. While currently we have only scratched the surface, understanding the role of the endocannabinoid system in personality may help in revealing the mechanisms underlying the etiopathology of psychiatric disorders.