1. Synthesis of a New Series of Chromones Based on Formylthiazoles.
- Author
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Tarasenko, D. O., Chumak, A. Y., Kolomoitsev, O. O., Kotliar, V. M., and Roshal, A. D.
- Subjects
THIAZOLES ,XANTHINE oxidase ,HYPERURICEMIA ,PYRAZOLONES ,AMINO acid sequence - Abstract
A preparative approach to thiazole-containing chromone derivatives has been developed by modifying the corresponding aldehydes with their further transformation into propenone derivatives, and finally introducing them into the Algar-FlynnOyamada reaction. Several methods for obtaining propenones have been analyzed, and the most effective and practically convenient one has been found. The thiazole-containing analogs of chromones obtained have a great potential as probes for a wide range of studies. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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