Search

Cerium binding activity of different water soluble pectin compounds varying according to their degree of esterification and insoluble calcium pectate beads in aqueous solution was studied in a batch sorption system. The cerium uptake by all pectin compounds was highest within the pH range from 4.0 to 6.0. The binding capacities and rates of cerium ions by pectin compounds were evaluated. The Langmuir, Freundlich and BET sorption models were applied to describe the isotherms and constants. Sorption isothermal data could be well interpreted by the Langmuir equation. The results obtained through the study suggest that pectin compounds are favorable sorbents. The largest amount of cerium ions is bound by pectin with the degree of esterification close to zero. Therefore, it can be concluded that low esterified pectins are more effective substances for elimination of cerium ions from aqueous disposals., (2010 Elsevier B.V. All rights reserved.)

Carrageenans are abundant and safe non-starch polysaccharides exerting their biological effects in living organisms. Apart from their known pro-inflammation properties and some pharmacological activity, carrageenans can also strongly bind and hold metal ions. This property can be used for creation of the new drugs for elimination of metals from the body or targeted delivery of these metal ions for healing purposes. Metal binding activity of different carrageenans in aqueous solutions containing Y(3+) or Pb(2+) ions was studied in a batch sorption system. The metal uptake by carrageenans is not affected by the change of the pH within the range from 2.0 to 6.0. The rates and binding capacities of carrageenans regarding metal ions were evaluated. The Langmuir, Freundlich and BET sorption models were applied to describe the isotherms and constants, and the sorption isothermal data could be explained well by the Langmuir equation. The results obtained through the study suggest that kappa-, iota-, and lambda-carrageenans are favorable sorbents. The largest amount of Y(3+) and Pb(2+) ions are bound by iota-carrageenan. Therefore, it can be concluded that this type of polysaccharide is the more appropriate substance for elaboration of the drugs with high selective metal binding properties.

The efficacy of an enterosorbent based on low-esterified pectin, activated charcoal, and polyphepan was evaluated in rats with experimental renal failure. Pectin was shown to be most effective. Its use causes increased daily diuresis and lower blood urine and creatinine levels in experimental animals. The findings have led to the conclusion that low-esterified pectin may be used to design drugs for the complex treatment in patients with chronic renal failure.

The zinc-binding activity of different water-soluble pectin compounds varying according to their degree of esterification and of insoluble calcium pectate beads in aqueous solution was studied in a batch sorption system. The zinc uptake by all pectin compounds was highest within the pH range from 4.0 to 7.0. The binding capacities and rates of zinc ions by pectin compounds were evaluated. The Langmuir, Freundlich, and BET sorption models were applied to describe the isotherms and constants. Sorption isotherm data could be well interpreted by the Langmuir equation. The results obtained through the study suggest that pectin compounds are favorable sorbents. The largest number of zinc ions are bound by pectin with the degree of esterification close to zero. Therefore, it can be concluded that low-esterified pectins are more effective substances for elimination of zinc ions from aqueous disposals.

Study of the effects of low-esterified pectin in toxic damage to the liver caused by enteral treatment with lead acetate showed that pectin treatment promoted the decrease in lead content in the liver, reduction of LPO activity, and recovery of parameters of lipid metabolism.