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5. De tweetalige ontwikkeling van dove kinderen in de Nederlandse Gebarentaal en het Nederlands. Een meervoudige casusstudie

Author

Kolen, E., Hout, R.W.N.M. van, Verhoeven, L.T.W., Klatter-Folmer, H.A.K., and Radboud University Nijmegen

Subjects
otorhinolaryngologic diseases, Communicative Competences
Abstract

Contains fulltext : 65651_tweeonvad.pdf (Publisher’s version ) (Open Access) Contains fulltext : 78738.pdf ( ) (Open Access) Many deaf children in the Netherlands grow up learning Sign Language of the Netherlands (SLN), spoken Dutch and/or a combination of both languages. A relevant question is what the language proficiency of the children is in these languages. Besides, it is important to know in what way the children use both languages in interaction with deaf and hearing communication partners. In the Dutch language area few data are available on this subject.This thesis describes a longitudinal multiple case study on language proficiency, communicative behaviour and communication strategies in SLN and Dutch of eleven deaf children in the age of three to seven years. The goal of this thesis was to gain insight in the bilingual language acquisition of deaf children and the influence of combined acquisition on the communication development. Semi-spontaneous conversations between the deaf children and deaf and hearing adults form the essence of the data collection. The children’s role in these conversations is analysed on three aspects: lexical and syntactic complexity of the utterances, communicative turns and the use of communicative strategies. Additionally, language proficiency was investigated by means of receptive and productive language tasks, and background information was collected by interviewing parents and teachers. The results of this study reveal new insights in the bilingual development of children with an auditory impairment and factors that are of influence on that development. This book is important for researchers, parents, teachers and policymakers. Radboud Universiteit Nijmegen, 11 februari 2009 Promotores : Hout, R.W.N.M. van, Verhoeven, L.T.W. Co-promotor : Klatter-Folmer, H.A.K. 362 p.

Published
2009

6. Deaf children in interaction with deaf and hearing adults: Development of language and communication

Author

Kolen, E., Klatter-Folmer, H.A.K., Hout, R.W.N.M. van, and Verhoeven, L.T.W.

Subjects
Oral language proficiency of SLI children. Linguistic analysis and communicative evaluation of the morphposyntactic expression of conceptual domains, Structuur in uitvoering, Structure in Use
Abstract

Item does not contain fulltext 20th International Congress on the Education of the Deaf Maastricht

Published
2005

9. De tweetalige ontwikkeling van dove kinderen in de Nederlandse Gebarentaal en het Nederlands. Een meervoudige casusstudie

Author

Hout, R.W.N.M. van, Verhoeven, L.T.W., Klatter-Folmer, H.A.K., Kolen, E., Hout, R.W.N.M. van, Verhoeven, L.T.W., Klatter-Folmer, H.A.K., and Kolen, E.

Abstract

Radboud Universiteit Nijmegen, 11 februari 2009, Promotores : Hout, R.W.N.M. van, Verhoeven, L.T.W. Co-promotor : Klatter-Folmer, H.A.K., Contains fulltext : 78738.pdf ( ) (Open Access), Many deaf children in the Netherlands grow up learning Sign Language of the Netherlands (SLN), spoken Dutch and/or a combination of both languages. A relevant question is what the language proficiency of the children is in these languages. Besides, it is important to know in what way the children use both languages in interaction with deaf and hearing communication partners. In the Dutch language area few data are available on this subject.This thesis describes a longitudinal multiple case study on language proficiency, communicative behaviour and communication strategies in SLN and Dutch of eleven deaf children in the age of three to seven years. The goal of this thesis was to gain insight in the bilingual language acquisition of deaf children and the influence of combined acquisition on the communication development. Semi-spontaneous conversations between the deaf children and deaf and hearing adults form the essence of the data collection. The children’s role in these conversations is analysed on three aspects: lexical and syntactic complexity of the utterances, communicative turns and the use of communicative strategies. Additionally, language proficiency was investigated by means of receptive and productive language tasks, and background information was collected by interviewing parents and teachers. The results of this study reveal new insights in the bilingual development of children with an auditory impairment and factors that are of influence on that development. This book is important for researchers, parents, teachers and policymakers.

Published
2009

11. Language development in deaf children’s interactions with deaf and hearing adults. A Dutch longitudinal study

Author

Klatter-Folmer, H.A.K., Hout, R.W.N.M. van, Kolen, E., Verhoeven, L.T.W., Klatter-Folmer, H.A.K., Hout, R.W.N.M. van, Kolen, E., and Verhoeven, L.T.W.

Abstract

Contains fulltext : 41903.pdf (publisher's version ) (Closed access), The language development of two deaf girls and four deaf boys in Sign Language of the Netherlands (SLN) and spoken Dutch was investigated longitudinally. At the start, the mean age of the children was 3;5. All data were collected in video-recorded semistructured conversations between individual children and deaf and hearing adults. We investigated the lexical richness and syntactic complexity of the children's utterances in SLN and spoken Dutch, as well as language dominance and interactional participation. Richness and complexity increase over time, as well as children's participation. An important outcome is that syntactic complexity is higher in utterances with both sign and speech. SLN does not have higher outcomes on richness or complexity, but is dominant in terms of frequency of use.

Published
2006

15. Language development in deaf children's interactions with deaf and hearing adults: a Dutch longitudinal study.

Author

Klatter-Folmer J, van Hout R, Kolen E, and Verhoeven L

Abstract

The language development of two deaf girls and four deaf boys in Sign Language of the Netherlands (SLN) and spoken Dutch was investigated longitudinally. At the start, the mean age of the children was 3;5. All data were collected in video-recorded semistructured conversations between individual children and deaf and hearing adults. We investigated the lexical richness and syntactic complexity of the children's utterances in SLN and spoken Dutch, as well as language dominance and interactional participation. Richness and complexity increase over time, as well as children's participation. An important outcome is that syntactic complexity is higher in utterances with both sign and speech. SLN does not have higher outcomes on richness or complexity, but is dominant in terms of frequency of use. [ABSTRACT FROM AUTHOR]

Published
2006

16. Congenital craniopharyngioma: a role for imaging in the prenatal diagnosis and treatment of an uncommon tumor.

Author

Kolen, E. R., Horvai, A., Perry, V., and Gupta, N.

Subjects
*ULTRASONIC imaging, *MAGNETIC resonance imaging, *TUMORS, *FETAL surgery, *DIAGNOSTIC imaging, *DIFFERENTIAL diagnosis, *FETAL diseases, *FETAL ultrasonic imaging, *PITUITARY tumors, *CRANIOPHARYNGIOMA
Abstract

Ultrasonography and magnetic resonance imaging performed upon a male fetus at 32 and 36 weeks gestation, respectively, revealed a large suprasellar mass. A male newborn, delivered at 37 weeks, required ventilatory assistance at birth and subsequently developed myoclonic seizures, hypertension, and bradycardia. The intracranial mass was felt to be inoperable and the patient expired shortly after support was withdrawn. Autopsy results were consistent with a congenital craniopharyngioma. We discuss the differential diagnosis for this mass lesion based on prenatal imaging as well as distinguishing features on imaging studies that may aid in the prenatal diagnosis and treatment of this benign tumor. [ABSTRACT FROM AUTHOR]

Published
2003
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17. Synapsin I is expressed in epithelial cells: localization to a unique trans-Golgi compartment.

Author

R, Bustos, R, Kolen E, L, Braiterman, J, Baines A, S, Gorelick F, and L, Hubbard A

Abstract

Synapsin I is abundant in neural tissues. Its phosphorylation is thought to regulate synaptic vesicle exocytosis in the pre-synaptic terminal by mediating vesicle tethering to the cytoskeleton. Using anti-synapsin antibodies, we detected an 85 kDa protein in liver cells and identified it as synapsin I. Like brain synapsin I, non-neuronal synapsin I is phosphorylated in vitro by protein kinase A and yields identical (32)P-peptide maps after limited proteolysis. We also detected synapsin I mRNA in liver by northern blot analysis. These results indicate that the expression of synapsin I is more widespread than previously thought. Immunofluorescence analysis of several non-neuronal cell lines localizes synapsin I to a vesicular compartment adjacent to trans-elements of the Golgi complex, which is also labeled with antibodies against myosin II; no sub-plasma membrane synapsin I is evident. We conclude that synapsin I is present in epithelial cells and is associated with a trans-Golgi network-derived compartment; this localization suggests that it plays a role in modulating post-TGN trafficking pathways.

Published
2001

18. Identification of the putative mammalian orthologue of Sec31P, a component of the COPII coat.

Author

Shugrue, C A, Kolen, E R, Peters, H, Czernik, A, Kaiser, C, Matovcik, L, Hubbard, A L, and Gorelick, F

Abstract

The regulation of intracellular vesicular trafficking is mediated by specific families of proteins that are involved in vesicular budding, translocation, and fusion with target membranes. We purified a vesicle-associated protein from hepatic microsomes using sequential column chromatography and partially sequenced it. Oliogonucleotides based on these sequences were used to clone the protein from a rat liver cDNA library. The clone encoded a novel protein with a predicted mass of 137 kDa (p137). The protein had an N terminus WD repeat motif with significant homology to Sec31p, a member of the yeast COPII coat that complexes with Sec13p. We found that p137 interacted with mammalian Sec13p using several approaches: co-elution through sequential column chromatography, co-immunoprecipitation from intact cells, and yeast two-hybrid analysis. Morphologically, the p137 protein was localized to small punctate structures in the cytoplasm of multiple cultured cell lines. When Sec13p was transfected into these cells, it demonstrated considerable overlap with p137. This overlap was maintained through several pharmacological manipulations. The p137 compartment also demonstrated partial overlap with ts045-VSVG protein when infected cells were incubated at 15 degrees C. These findings suggest that p137 is the mammalian orthologue of Sec31p.

Published
1999

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