472 results on '"Koivunen, Peppi"'
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2. Activation of the hypoxia-inducible factor pathway by roxadustat improves glucose metabolism in human primary myotubes from men
3. Hemoglobin levels are associated with retinal vascular caliber in a middle-aged birth cohort
4. Glutarate regulates T cell metabolism and anti-tumour immunity
5. Iron drives anabolic metabolism through active histone demethylation and mTORC1
6. PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase
7. Supplementary Figure S8 from A Histone Methylation–MAPK Signaling Axis Drives Durable Epithelial–Mesenchymal Transition in Hypoxic Pancreatic Cancer
8. Data from A Histone Methylation–MAPK Signaling Axis Drives Durable Epithelial–Mesenchymal Transition in Hypoxic Pancreatic Cancer
9. Supplementary Data from A Histone Methylation–MAPK Signaling Axis Drives Durable Epithelial–Mesenchymal Transition in Hypoxic Pancreatic Cancer
10. Contribution of HIF-P4H isoenzyme inhibition to metabolism indicates major beneficial effects being conveyed by HIF-P4H-2 antagonism
11. Higher hemoglobin levels are an independent risk factor for gestational diabetes
12. Activation of the hypoxia response pathway protects against age-induced cardiac hypertrophy
13. Higher haemoglobin levels are associated with impaired periodontal status.
14. Activation of the hypoxia response protects mice from amyloid-β accumulation
15. A 2-Hydroxybutyrate- mediated feedback loop regulates muscular fatigue
16. Lower hemoglobin levels associate with higher baroreflex sensitivity and heart rate variability
17. 2-Oxoglutarate-dependent dioxygenases in cancer
18. Higher hemoglobin levels are an independent risk factor for adverse metabolism and higher mortality in a 20-year follow-up
19. HIF-P4H-2 inhibition enhances intestinal fructose metabolism and induces thermogenesis protecting against NAFLD
20. Biallelic loss-of-function P4HTM gene variants cause hypotonia, hypoventilation, intellectual disability, dysautonomia, epilepsy, and eye abnormalities (HIDEA syndrome)
21. Maternal hemoglobin associates with preterm delivery and small for gestational age in two Finnish birth cohorts
22. The Circadian Clock Protein CRY1 Is a Negative Regulator of HIF-1α
23. Hypoxia-Inducible Factor Prolyl 4-Hydroxylases and Metabolism
24. Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase.
25. Remote ischemic preconditioning and hypoxia-induced biomarkers in acute myocardial infarction: study on a porcine model
26. Characterization of genetic variants in the EGLN1/PHD2 gene identified in a European collection of patients with erythrocytosis
27. Supplementary Figure S5 from (R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers
28. Human phytanoyl‐CoA dioxygenase domain‐containing 1 (PHYHD1) is a putative oxygen sensor associated with RNA and carbohydrate metabolism
29. Supplementary Table S8 from (R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers
30. Data from (R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers
31. Supplementary Data: list of figures and tables from (R)-2-Hydroxyglutarate Inhibits KDM5 Histone Lysine Demethylases to Drive Transformation in IDH-Mutant Cancers
32. Figure S4 from USP28 Deficiency Promotes Breast and Liver Carcinogenesis as well as Tumor Angiogenesis in a HIF-independent Manner
33. Supplemental table 1 from USP28 Deficiency Promotes Breast and Liver Carcinogenesis as well as Tumor Angiogenesis in a HIF-independent Manner
34. Supplemental table 2 from USP28 Deficiency Promotes Breast and Liver Carcinogenesis as well as Tumor Angiogenesis in a HIF-independent Manner
35. Author Correction: Hypoxia causes reductions in birth weight by altering maternal glucose and lipid metabolism
36. The TET enzymes
37. Data from The Pro-Oncogenic Adaptor CIN85 Acts as an Inhibitory Binding Partner of Hypoxia-Inducible Factor Prolyl Hydroxylase 2
38. Supplementary Materials and Methods from The Pro-Oncogenic Adaptor CIN85 Acts as an Inhibitory Binding Partner of Hypoxia-Inducible Factor Prolyl Hydroxylase 2
39. Supplementary Data from The Pro-Oncogenic Adaptor CIN85 Acts as an Inhibitory Binding Partner of Hypoxia-Inducible Factor Prolyl Hydroxylase 2
40. (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
41. Kinetic Analysis of HIF Prolyl Hydroxylases
42. Sodium valproate induces mitochondrial respiration dysfunction in HepG2 in vitro cell model
43. A histone methylation-MAPK signaling axis drives durable epithelial-mesenchymal transition in hypoxic pancreas cancer
44. Iron Drives Anabolic Metabolism Through Active Histone Demethylation and mTORC1
45. HIDEA syndrome is caused by biallelic, pathogenic, rare or founder P4HTM variants impacting the active site or the overall stability of the P4H‐TM protein
46. Hypoxia causes reductions in birth weight by altering maternal glucose and lipid metabolism
47. HIF-P4H-2 deficiency protects against skeletal muscle ischemia-reperfusion injury
48. Abstract 5853: (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive tumorigenesis in IDH-mutant cancers
49. Hypoxia ameliorates maternal diet‐induced insulin resistance during pregnancy while having a detrimental effect on the placenta
50. (R)-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
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