343 results on '"Koglin, J."'
Search Results
2. Performance of ePix10K, a high dynamic range, gain auto-ranging pixel detector for FELs
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Blaj, G., Dragone, A., Kenney, C. J., Abu-Nimeh, F., Caragiulo, P., Doering, D., Kwiatkowski, M., Pines, J., Weaver, M., Boutet, S., Carini, G., Chang, C. -E., Hart, P., Hasi, J., Hayes, M., Herbst, R., Koglin, J., Nakahara, K., Segal, J., and Haller, G.
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Physics - Instrumentation and Detectors - Abstract
ePix10K is a hybrid pixel detector developed at SLAC for demanding free-electron laser (FEL) applications, providing an ultrahigh dynamic range (245 eV to 88 MeV) through gain auto-ranging. It has three gain modes (high, medium and low) and two auto-ranging modes (high-to-low and medium-to-low). The first ePix10K cameras are built around modules consisting of a sensor flip-chip bonded to 4 ASICs, resulting in 352x384 pixels of 100 $\mu$m x 100 $\mu$m each. We present results from extensive testing of three ePix10K cameras with FEL beams at LCLS, resulting in a measured noise floor of 245 eV rms, or 67 e$^-$ equivalent noise charge (ENC), and a range of 11000 photons at 8 keV. We demonstrate the linearity of the response in various gain combinations: fixed high, fixed medium, fixed low, auto-ranging high to low, and auto-ranging medium-to-low, while maintaining a low noise (well within the counting statistics), a very low cross-talk, perfect saturation response at fluxes up to 900 times the maximum range, and acquisition rates of up to 480 Hz. Finally, we present examples of high dynamic range x-ray imaging spanning more than 4 orders of magnitude dynamic range (from a single photon to 11000 photons/pixel/pulse at 8 keV). Achieving this high performance with only one auto-ranging switch leads to relatively simple calibration and reconstruction procedures. The low noise levels allow usage with long integration times at non-FEL sources. ePix10K cameras leverage the advantages of hybrid pixel detectors with high production yield and good availability, minimize development complexity through sharing the hardware, software and DAQ development with all other versions of ePix cameras, while providing an upgrade path to 5 kHz, 25 kHz and 100 kHz in three steps over the next few years, matching the LCLS-II requirements., Comment: 9 pages, 5 figures
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- 2019
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3. Optimal pulse processing, pile-up decomposition and applications of silicon drift detectors at LCLS
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Blaj, G., Kenney, C. J., Dragone, A., Carini, G., Herrmann, S., Hart, P., Tomada, A., Koglin, J., Haller, G., Boutet, S., Messerschmidt, M., Williams, G., Chollet, M., Dakovski, G., Nelson, S., Pines, J., Song, S., and Thayer, J.
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Physics - Instrumentation and Detectors ,Physics - Data Analysis, Statistics and Probability - Abstract
Silicon drift detectors (SDDs) revolutionized spectroscopy in fields as diverse as geology and dentistry. For a subset of experiments at ultra-fast, x-ray free-electron lasers (FELs), SDDs can make substantial contributions. Often the unknown spectrum is interesting, carrying science data, or the background measurement is useful to identify unexpected signals. Many measurements involve only several discrete photon energies known a priori, allowing single event decomposition of pile-up and spectroscopic photon counting. We designed a pulse function and demonstrated that the signal amplitude and rise time are obtained for each pulse by fitting, thus removing the need for pulse shaping. By avoiding pulse shaping, rise times of tens of nanoseconds resulted in reduced pulse pile-up and allowed decomposition of remaining pulse pile-up at photon separation times down to hundreds of nanoseconds while yielding time-of-arrival information with precision of 10 nanoseconds. Waveform fitting yields simultaneously high energy resolution and high counting rates (2 orders of magnitude higher than current digital pulse processors). We showed that pile-up spectrum fitting is relatively simple and preferable to pile-up spectrum deconvolution. We developed a photon pile-up statistical model for constant intensity sources, extended it to variable intensity sources (typical for FELs) and used it to fit a complex pile-up spectrum. We subsequently developed a Bayesian pile-up decomposition method that allows decomposing pile-up of single events with up to 6 photons from 6 monochromatic lines with 99% accuracy. The usefulness of SDDs will continue into the x-ray FEL era of science. Their successors, the ePixS hybrid pixel detectors, already offer hundreds of pixels, each with similar performance to an SDD, in a compact, robust and affordable package, Comment: 16 pages, 11 figures, 4 tables
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- 2017
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4. The NuSTAR Hard X-ray Survey of the Norma Arm Region
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Fornasini, Francesca M., Tomsick, John A., Hong, JaeSub, Gotthelf, Eric V., Bauer, Franz, Rahoui, Farid, Stern, Daniel, Bodaghee, Arash, Chiu, Jeng-Lun, Clavel, Maïca, Corral-Santana, Jesús M., Hailey, Charles J., Krivonos, Roman A., Mori, Kaya, Alexander, David M., Barret, Didier, Boggs, Steven E., Christensen, Finn E., Craig, William W., Forster, Karl, Giommi, Paolo, Grefenstette, Brian W., Harrison, Fiona A., Hornstrup, Allan, Kitaguchi, Takao, Koglin, J. E., Madsen, Kristin K., Mao, Peter H., Miyasaka, Hiromasa, Perri, Matteo, Pivovaroff, Michael J., Puccetti, Simonetta, Rana, Vikram, Westergaard, Niels J., and Zhang, William W.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We present a catalog of hard X-ray sources in a square-degree region surveyed by NuSTAR in the direction of the Norma spiral arm. This survey has a total exposure time of 1.7 Ms, and typical and maximum exposure depths of 50 ks and 1 Ms, respectively. In the area of deepest coverage, sensitivity limits of $5\times10^{-14}$ and $4\times10^{-14}$ erg s$^{-1}$ cm$^{-2}$ in the 3-10 and 10-20 keV bands, respectively, are reached. Twenty-eight sources are firmly detected and ten are detected with low significance; eight of the 38 sources are expected to be active galactic nuclei. The three brightest sources were previously identified as a low-mass X-ray binary, high-mass X-ray binary, and pulsar wind nebula. Based on their X-ray properties and multi-wavelength counterparts, we identify the likely nature of the other sources as two colliding wind binaries, three pulsar wind nebulae, a black hole binary, and a plurality of cataclysmic variables (CVs). The CV candidates in the Norma region have plasma temperatures of $\approx$10-20 keV, consistent with the Galactic Ridge X-ray emission spectrum but lower than temperatures of CVs near the Galactic Center. This temperature difference may indicate that the Norma region has a lower fraction of intermediate polars relative to other types of CVs compared to the Galactic Center. The NuSTAR log$N$-log$S$ distribution in the 10-20 keV band is consistent with the distribution measured by Chandra at 2-10 keV if the average source spectrum is assumed to be a thermal model with $kT\approx15$~keV, as observed for the CV candidates., Comment: 42 pages, 12 figures, 11 tables
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- 2017
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5. The distribution of radioactive $^{44}$Ti in Cassiopeia A
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Grefenstette, Brian W., Fryer, Chris L., Harrison, Fiona A., Boggs, Steven E., DeLaney, Tracey, Laming, J. Martin, Reynolds, Stephen P., Alexander, David M., Barret, Didier, Christensen, Finn E., Craig, William W., Forster, Karl, Giommi, Paolo, Hailey, Charles J., Hornstrup, Alan, Kitaguchi, Takao, Koglin, J. E., Lopez, Laura, Mao, Peter H., Madsen, Kristin K., Miyasaka, Hiromasa, Mori, Kaya, Perri, Matteo, Pivovaroff, Michael J., Puccetti, Simonetta, Rana, Vikram, Stern, Daniel, Westergaard, Niels J., Wik, Daniel R., Zhang, William W., and Zoglauer, Andreas
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The distribution of elements produced in the inner-most layers of a supernova explosion is a key diagnostic for studying the collapse of massive stars. Here we present the results of a 2.4 Ms \textit{NuSTAR} observing campaign aimed at studying the supernova remnant Cassiopeia A (Cas A). We perform spatially-resolved spectroscopic analyses of the $^{44}$Ti ejecta which we use to determine the Doppler shift and thus the three-dimensional (3D) velocities of the $^{44}$Ti ejecta. We find an initial $^{44}$Ti mass of 1.54 $\pm$ 0.21 $\times 10^{-4}$ M$_{\odot}$ which has a present day average momentum direction of 340$^{\circ}$ $\pm$ 15$^{\circ}$ projected on to the plane of the sky (measured clockwise from Celestial North) and tilted by 58$^{\circ}$ $\pm$ 20$^{\circ}$ into the plane of the sky away from the observer, roughly opposite to the inferred direction of motion of the central compact object. We find some $^{44}$Ti ejecta that are clearly interior to the reverse shock and some that are clearly exterior to the reverse shock. Where we observe $^{44}$Ti ejecta exterior to the reverse shock we also see shock-heated iron; however, there are regions where we see iron but do not observe $^{44}$Ti. This suggests that the local conditions of the supernova shock during explosive nucleosynthesis varied enough to suppress the production of $^{44}$Ti in some regions by at least a factor of two, even in regions that are assumed to be the result of processes like $\alpha$-rich freezeout that should produce both iron and titanium., Comment: 14 pages, 13 figures (6 3D animations in the online journal). Accepted for publication in ApJ
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- 2016
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6. First NuSTAR observations of the BL Lac - type blazar PKS~2155-304: constraints on the jet content and distribution of radiating particles
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Madejski, G. M., Nalewajko, K., Madsen, K. K., Chiang, J., Baloković, M., Paneque, D., Furniss, A. K., Hayashida, M., Urry, C. M., Sikora, M., Ajello, M., Blandford, R. D., Harrison, F. A., Sanchez, D., Giebels, B., Stern, D., Alexander, D. M., Barret, D., Boggs, S. E., Christensen, F. E., Craig, W. W., Forster, K., Giommi, P., Grefenstette, B., Hailey, C., Hornstrup, A., Kitaguchi, T., Koglin, J. E., Mao, P. H., Miyasaka, H., Mori, K., Perri, M., Pivovaroff, M. J., Puccetti, S., Rana, V., Westergaard, N. J., Zhang, W. W., and Zoglauer, A.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We report the first hard X-ray observations with NuSTAR of the BL Lac type blazar PKS 2155-304, augmented with soft X-ray data from XMM-Newton and gamma-ray data from the Fermi Large Area Telescope, obtained in April 2013 when the source was in a very low flux state. A joint NuSTAR and XMM spectrum, covering the energy range 0.5 - 60 keV, is best described by a model consisting of a log-parabola component with curvature beta = 0.3(+0.2,-0.1) and a (local) photon index 3.04 +/- 0.15 at photon energy of 2 keV, and a hard power-law tail with photon index 2.2 +/- 0.4. The hard X-ray tail can be smoothly joined to the quasi-simultaneous gamma-ray spectrum by a synchrotron self-Compton component produced by an electron distribution with index p = 2.2. Assuming that the power-law electron distribution extends down to the minimum electron Lorentz factor gamma_min = 1 and that there is one proton per electron, an unrealistically high total jet power L_p of roughly 10^47 erg/s is inferred. This can be reduced by two orders of magnitude either by considering a significant presence of electron-positron pairs with lepton-to-proton ratio of at least 30, or by introducing an additional, low-energy break in the electron energy distribution at the electron Lorentz factor gamma_br1 of roughly 100. In either case, the jet composition is expected to be strongly matter-dominated., Comment: Astrophysical Journal, in press
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- 2016
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7. First observation of low-energy {\gamma}-ray enhancement in the rare-earth region
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Simon, A., Guttormsen, M., Larsen, A. C., Beausang, C. W., Humby, P., Burke, J. T., Casperson, R. J., Hughes, R. O., Ross, T. J., Allmond, J. M., Chyzh, R., Dag, M., Koglin, J., McCleskey, E., McCleskey, M., Ota, S., and Saastamoinen, A.
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Nuclear Experiment - Abstract
The {\gamma}-ray strength function and level density in the quasi-continuum of 151,153Sm have been measured using BGO shielded Ge clover detectors of the STARLiTeR system. The Compton shields allow for an extraction of the {\gamma} strength down to unprecedentedly low {\gamma} energies of about 500 keV. For the first time an enhanced low- energy {\gamma}-ray strength has been observed in the rare-earth region. In addition, for the first time both the upbend and the well known scissors resonance have been observed simultaneously for the same nucleus. Hauser-Feshbach calculations show that this strength enhancement at low {\gamma} energies could have an impact of 2-3 orders of magnitude on the (n,{\gamma}) reaction rates for the r-process nucleosynthesis.
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- 2016
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8. Multiwavelength Study of Quiescent States of Mrk 421 with Unprecedented Hard X-Ray Coverage Provided by NuSTAR in 2013
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Baloković, M., Paneque, D., Madejski, G., Furniss, A., Chiang, J., team, the NuSTAR, Ajello, M., Alexander, D. M., Barret, D., Blandford, R., Boggs, S. E., Christensen, F. E., Craig, W. W., Forster, K., Giommi, P., Grefenstette, B. W., Hailey, C. J., Harrison, F. A., Hornstrup, A., Kitaguchi, T., Koglin, J. E., Madsen, K. K., Mao, P. H., Miyasaka, H., Mori, K., Perri, M., Pivovaroff, M. J., Puccetti, S., Rana, V., Stern, D., Tagliaferri, G., Urry, C. M., Westergaard, N. J., Zhang, W. W., Zoglauer, A., collaboration, the VERITAS, Archambault, S., Archer, A. A., Barnacka, A., Benbow, W., Bird, R., Buckley, J., Bugaev, V., Cerruti, M., Chen, X., Ciupik, L., Connolly, M. P., Cui, W., Dickinson, H. J., Dumm, J., Eisch, J. D., Falcone, A., Feng, Q., Finley, J. P., Fleischhack, H., Fortson, L., Griffin, S., Griffiths, S. T., Grube, J., Gyuk, G., Huetten, M., Haakansson, N., Holder, J., Humensky, T. B., Johnson, C. A., Kaaret, P., Kertzman, M., Khassen, Y., Kieda, D., Krause, M., Krennrich, F., Lang, M. J., Maier, G., McArthur, S., Meagher, K., Moriarty, P., Nelson, T., Nieto, D., Ong, R. A., Park, N., Pohl, M., Popkow, A., Pueschel, E., Reynolds, P. T., Richards, G. T., Roache, E., Santander, M., Sembroski, G. H., Shahinyan, K., Smith, A. W., Staszak, D., Telezhinsky, I., Todd, N. W., Tucci, J. V., Tyler, J., Vincent, S., Weinstein, A., Wilhelm, A., Williams, D. A., Zitzer, B., collaboration, the MAGIC, Ahnen, M. L., Ansoldi, S., Antonelli, L. A., Antoranz, P., Babic, A., Banerjee, B., Bangale, P., de Almeida, U. Barres, Barrio, J., González, J. Becerra, Bednarek, W., Bernardini, E., Biasuzzi, B., Biland, A., Blanch, O., Bonnefoy, S., Bonnoli, G., Borracci, F., Bretz, T., Carmona, E., Carosi, A., Chatterjee, A., Clavero, R., Colin, P., Colombo, E., Contreras, J. L., Cortina, J., Covino, S., Da Vela, P., Dazzi, F., de Angelis, A., De Lotto, B., Wilhelmi, E. D. de Oña, Mendez, C. Delgado, Di Pierro, F., Prester, D. Dominis, Dorner, D., Doro, M., Einecke, S., Elsaesser, D., Fernández-Barral, A., Fidalgo, D., Fonseca, M. V., Font, L., Frantzen, K., Fruck, C., Galindo, D., López, R. J. García, Garczarczyk, M., Terrats, D. Garrido, Gaug, M., Giammaria, P., Eisenacher, D., Godinović, N., Muñoz, A. González, Guberman, D., Hahn, A., Hanabata, Y., Hayashida, M., Herrera, J., Hose, J., Hrupec, D., Hughes, G., Idec, W., Kodani, K., Konno, Y., Kubo, H., Kushida, J., La Barbera, A., Lelas, D., Lindfors, E., Lombardi, S., Longo, F., López, M., López-Coto, R., López-Oramas, A., Lorenz, E., Majumdar, P., Makariev, M., Mallot, K., Maneva, G., Manganaro, M., Mannheim, K., Maraschi, L., Marcote, B., Mariotti, M., Martínez, M., Mazin, D., Menzel, U., Miranda, J. M., Mirzoyan, R., Moralejo, A., Moretti, E., Nakajima, D., Neustroev, V., Niedzwiecki, A., Nievas-Rosillo, M., Nilsson, K., Nishijima, K., Noda, K., Orito, R., Overkemping, A., Paiano, S., Palacio, S., Palatiello, M., Paoletti, R., Paredes, J. M., Paredes-Fortuny, X., Persic, M., Poutanen, J., Moroni, P. G. Prada, Prandini, E., Puljak, I., Rhode, W., Ribó, M., Rico, J., Garcia, J. Rodriguez, Saito, T., Satalecka, K., Scapin, V., Schultz, C., Schweizer, T., Shore, S. N., Sillanpää, A., Sitarek, J., Snidaric, I., Sobczynska, D., Stamerra, A., Steinbring, T., Strzys, M., Takalo, L. O., Takami, H., Tavecchio, F., Temnikov, P., Terzić, T., Tescaro, D., Teshima, M., Thaele, J., Torres, D. F., Toyama, T., Treves, A., Verguilov, V., Vovk, I., Ward, J. E., Will, M., Wu, M. H., Zanin, R., collaborators, external, Perkins, J., Verrecchia, F., Leto, C., Böttcher, M., Villata, M., Raiteri, C. M., Acosta-Pulido, J. A., Bachev, R., Berdyugin, A., Blinov, D. A., Carnerero, M. I., Chen, W. P., Chinchilla, P., Damljanovic, G., Eswaraiah, C., Grishina, T. S., Ibryamov, S., Jordan, B., Jorstad, S. G., Joshi, M., Kopatskaya, E. N., Kurtanidze, O. M., Kurtanidze, S. O., Larionova, E. G., Larionova, L. V., Larionov, V. M., Latev, G., Lin, H. C., Marscher, A. P., Mokrushina, A. A., Morozova, D. A., Nikolashvili, M. G., Semkov, E., Strigachev, A., Troitskaya, Yu. V., Troitsky, I. S., Vince, O., Barnes, J., Güver, T., Moody, J. W., Sadun, A. C., Sun, S., Hovatta, T., Richards, J. L., Max-Moerbeck, W., Readhead, A. C., Lähteenmäki, A., Tornikoski, M., Tammi, J., Ramakrishnan, V., Reinthal, R., Angelakis, E., Fuhrmann, L., Myserlis, I., Karamanavis, V., Sievers, A., Ungerechts, H., and Zensus, J. A.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We present coordinated multiwavelength observations of the bright, nearby BL Lac object Mrk 421 taken in 2013 January-March, involving GASP-WEBT, Swift, NuSTAR, Fermi-LAT, MAGIC, VERITAS, and other collaborations and instruments, providing data from radio to very-high-energy (VHE) gamma-ray bands. NuSTAR yielded previously unattainable sensitivity in the 3-79 keV range, revealing that the spectrum softens when the source is dimmer until the X-ray spectral shape saturates into a steep power law with a photon index of approximately 3, with no evidence for an exponential cutoff or additional hard components up to about 80 keV. For the first time, we observed both the synchrotron and the inverse-Compton peaks of the spectral energy distribution (SED) simultaneously shifted to frequencies below the typical quiescent state by an order of magnitude. The fractional variability as a function of photon energy shows a double-bump structure which relates to the two bumps of the broadband SED. In each bump, the variability increases with energy which, in the framework of the synchrotron self-Compton model, implies that the electrons with higher energies are more variable. The measured multi-band variability, the significant X-ray-to-VHE correlation down to some of the lowest fluxes ever observed in both bands, the lack of correlation between optical/UV and X-ray flux, the low degree of polarization and its significant (random) variations, the short estimated electron cooling time, and the significantly longer variability timescale observed in the NuSTAR light curves point toward in-situ electron acceleration, and suggest that there are multiple compact regions contributing to the broadband emission of Mrk 421 during low-activity states., Comment: 32 pages, 14 figures; accepted for publication in ApJ
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- 2015
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9. The NuSTAR Extragalactic Surveys: The Number Counts of Active Galactic Nuclei and the Resolved Fraction of the Cosmic X-ray Background
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Harrison, F. A., Aird, J., Civano, F., Lansbury, G., Mullaney, J. R., Ballantyne, D. R., Alexander, D. M., Stern, D., Ajello, M., Barret, D., Bauer, F. E., Balokovic, M., Brandt, W. N., Brightman, M., Boggs, S. E., Christensen, F. E., Comastri, A., Craig, W. W., Del Moro, A., Forster, K., Gandhi, P., Giommi, P., Grefenstette, B. W., Hailey, C. J., Hickox, R. C., Hornstrup, A., Kitaguchi, T., Koglin, J., Luo, B., Madsen, K. K., Mao, P. H., Miyasaka, H., Mori, K., Perri, M., Pivovaroff, M., Puccetti, S., Rana, V., Treister, E., Walton, D., Westergaard, N. J., Wik, D., Zappacosta, L., Zhang, W. W., and Zoglauer, A.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
We present the 3-8 keV and 8-24 keV number counts of active galactic nuclei (AGN) identified in the NuSTAR extragalactic surveys. NuSTAR has now resolved 33-39% of the X-ray background in the 8-24 keV band, directly identifying AGN with obscuring columns up to approximately 1e25 /cm2. In the softer 3-8 keV band the number counts are in general agreement with those measured by XMM-Newton and Chandra over the flux range 5e-15 < S(3 - 8 keV)/(erg/cm2/s) < 1e-12 probed by NuSTAR. In the hard 8-24 keV band NuSTAR probes fluxes over the range 2e-14 < S(8-24 keV)/(erg/cm2/s) < 1e-12, a factor of approximately 100 fainter than previous measurements. The 8-24 keV number counts match predictions from AGN population synthesis models, directly confirming the existence of a population of obscured and/or hard X-ray sources inferred from the shape of the integrated cosmic X-ray background. The measured NuSTAR counts lie significantly above simple extrapolation with a Euclidian slope to low flux of the Swift/BAT 15-55 keV number counts measured at higher fluxes S(15-55 keV) > 1e-11 erg/cm2/s, reflecting the evolution of the AGN population between the Swift/BAT local (z<0.1) sample and NuSTAR's z~1 sample. CXB synthesis models, which account for AGN evolution, lie above the Swift/BAT measurements, suggesting that they do not fully capture the evolution of obscured AGN at low redshifts., Comment: 8 pages; accepted by the Astrophysical Journal
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- 2015
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10. Se-SAD serial femtosecond crystallography datasets from selenobiotinyl-streptavidin
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Yoon, C, DeMirci, H, Sierra, R, Dao, E, Ahmadi, R, Aksit, F, Aquila, A, Batyuk, A, Ciftci, H, Guillet, A, Hayes, B, Lane, T, Liang, M, Lundstrom, U, Koglin, J, Mgbam, P, Rao, Y, Rendahl, T, Rodriguez, E, Zhang, L, Wakatsuki, S, Boutet, S, Holton, J, and Hunter, M
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- 2017
11. Rapid Variability of Blazar 3C 279 during Flaring States in 2013-2014 with Joint Fermi-LAT, NuSTAR, Swift, and Ground-Based Multi-wavelength Observations
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Hayashida, M., Nalewajko, K., Madejski, G. M., Sikora, M., Itoh, R., Ajello, M., Blandford, R. D., Buson, S., Chiang, J., Fukazawa, Y., Furniss, A. K., Urry, C. M., Hasan, I., Harrison, F. A., Alexander, D. M., Baloković, M., Barret, D., Boggs, S. E., Christensen, F. E., Craig, W. W., Forster, K., Giommi, P., Grefenstette, B., Hailey, C., Hornstrup, A., Kitaguchi, T., Koglin, J. E., Madsen, K. K., Mao, P. H., Miyasaka, H., Mori, K., Perri, M., Pivovaroff, M. J., Puccetti, S., Rana, V., Stern, D., Tagliaferri, G., Westergaard, N. J., Zhang, W. W., Zoglauer, A., Gurwell, M. A., Uemura, M., Akitaya, H., Kawabata, K. S., Kawaguch, K., Kanda, Y., Moritani, Y., Takaki, K., Ui, T., Yoshida, M., Agarwal, A., and Gupta, A. C.
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Astrophysics - High Energy Astrophysical Phenomena ,Astrophysics - Astrophysics of Galaxies - Abstract
We report the results of a multi-band observing campaign on the famous blazar 3C 279 conducted during a phase of increased activity from 2013 December to 2014 April, including first observations of it with NuSTAR. The $\gamma$-ray emission of the source measured by Fermi-LAT showed multiple distinct flares reaching the highest flux level measured in this object since the beginning of the Fermi mission, with $F(E > 100\,{\rm MeV})$ of $10^{-5}$ photons cm$^{-2}$ s$^{-1}$, and with a flux doubling time scale as short as 2 hours. The $\gamma$-ray spectrum during one of the flares was very hard, with an index of $\Gamma_\gamma = 1.7 \pm 0.1$, which is rarely seen in flat spectrum radio quasars. The lack of concurrent optical variability implies a very high Compton dominance parameter $L_\gamma/L_{\rm syn} > 300$. Two 1-day NuSTAR observations with accompanying Swift pointings were separated by 2 weeks, probing different levels of source activity. While the 0.5$-$70 keV X-ray spectrum obtained during the first pointing, and fitted jointly with Swift-XRT is well-described by a simple power law, the second joint observation showed an unusual spectral structure: the spectrum softens by $\Delta\Gamma_{\rm X} \simeq 0.4$ at $\sim$4 keV. Modeling the broad-band SED during this flare with the standard synchrotron plus inverse Compton model requires: (1) the location of the $\gamma$-ray emitting region is comparable with the broad line region radius, (2) a very hard electron energy distribution index $p \simeq 1$, (3) total jet power significantly exceeding the accretion disk luminosity $L_{\rm j}/L_{\rm d} \gtrsim 10$, and (4) extremely low jet magnetization with $L_{\rm B}/L_{\rm j} \lesssim 10^{-4}$. We also find that single-zone models that match the observed $\gamma$-ray and optical spectra cannot satisfactorily explain the production of X-ray emission., Comment: 17 pages, 10 figures, accepted for publication in The Astrophysical Journal
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- 2015
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12. Selenium single-wavelength anomalous diffraction de novo phasing using an X-ray-free electron laser
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Hunter, M S, Yoon, C H, DeMirci, H, Sierra, R G, Dao, E H, Ahmadi, R, Askit, F, Aquila, A L, Ciftci, H, Guillet, S, Hayes, M J, Lane, T J, Liang, M, Lundstrom, U, Koglin, J E, Mgbam, P, Rao, Y, Zhang, L, Wakatsuki, S, Holton, J M, and Boutet, S
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- 2016
13. Asymmetries in core-collapse supernovae from maps of radioactive $^{44}$Ti in CassiopeiaA
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Grefenstette, B. W., Harrison, F. A., Boggs, S. E., Reynolds, S. P., Fryer, C. L., Madsen, K. K., Wik, D. R., Zoglauer, A., Ellinger, C. I., Alexander, D. M., An, H., Barret, D., Christensen, F. E., Craig, W. W., Forster, K., Giommi, P., Hailey, C. J., Hornstrup, A., Kaspi, V. M., Kitaguchi, T., Koglin, J. E., Mao, P. H., Miyasaka, H., Mori, K., Perri, M., Pivovaroff, M. J., Puccetti, S, Rana, V., Stern, D., Westergaard, N. J., and Zhang, W. W.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Asymmetry is required by most numerical simulations of stellar core-collapse explosions, but the form it takes differs significantly among models. The spatial distribution of radioactive 44Ti, synthesized in an exploding star near the boundary between material falling back onto the collapsing core and that ejected into the surrounding medium, directly probes the explosion asymmetries. CassiopeiaA is a young, nearby, core-collapse remnant from which 44Ti emission has previously been detected but not imaged. Asymmetries in the explosion have been indirectly inferred from a high ratio of observed 44Ti emission to estimated 56Ni emission, from optical light echoes, and from jet-like features seen in the X-ray and optical ejecta. Here we report spatial maps and spectral properties of the 44Ti in Cassiopeia A. This may explain the unexpected lack of correlation between the 44Ti and iron X-ray emission, the latter being visible only in shock-heated material. The observed spatial distribution rules out symmetric explosions even with a high level of convective mixing, as well as highly asymmetric bipolar explosions resulting from a fast-rotating progenitor. Instead, these observations provide strong evidence for the development of low-mode convective instabilities in core-collapse supernovae., Comment: 32 pages, Figures Embedded
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- 2014
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14. First Results from NuSTAR Observations of Mkn 421
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Baloković, M., Ajello, M., Blandford, R. D., Boggs, S. E., Borracci, F., Chiang, J., Christensen, F. E., Craig, W. W., Forster, K., Furniss, A., Fuerst, F., Ghisellini, G., Giebels, B., Giommi, P., Grefenstette, B. W., Hailey, C. J., Harrison, F. A., Hayashida, M., Humensky, B., Inoue, Y., Koglin, J. E., Krawczynski, H., Madejski, G. M., Madsen, K. K., Meier, D. L., Nelson, T., Ogle, P., Paneque, D., Perri, M., Puccetti, S., Reynolds, C. S., Sbarrato, T., Stern, D., Tagliaferri, G., Urry, C. M., Wehrle, A. E., and Zhang, W. W.
- Subjects
Astrophysics - High Energy Astrophysical Phenomena - Abstract
Mkn 421 is a nearby active galactic nucleus dominated at all wavelengths by a very broad non-thermal continuum thought to arise from a relativistic jet seen at a small angle to the line of sight. Its spectral energy distribution peaks in the X-ray and TeV gamma-ray bands, where the energy output is dominated by cooling of high-energy electrons in the jet. In order to study the electron distribution and its evolution, we carried out a dedicated multi-wavelength campaign, including extensive observations by the recently launched highly sensitive hard X-ray telescope NuSTAR, between December 2012 and May 2013. Here we present some initial results based on NuSTAR data from January through March 2013, as well as calibration observations conducted in 2012. Although the observations cover some of the faintest hard X-ray flux states ever observed for Mkn 421, the sensitivity is high enough to resolve intra-day spectral variability. We find that in this low state the dominant flux variations are smooth on timescales of hours, with typical intra-hour variations of less than 5%. We do not find evidence for either a cutoff in the hard X-ray spectrum, or a rise towards a high-energy component, but rather that at low flux the spectrum assumes a power law shape with a photon index of approximately 3. The spectrum is found to harden with increasing brightness., Comment: 4 pages, 4 figures; to appear in "The Innermost Regions of Relativistic Jets and Their Magnetic Fields" conference proceedings; updated with minor corrections
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- 2013
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15. The flight of the GAPS prototype experiment
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von Doetinchem, P., Aramaki, T., Bando, N., Boggs, S. E., Fuke, H., Gahbauer, F. H., Hailey, C. J., Koglin, J. E., Mognet, S. A. I., Madden, N., Okazaki, S., Ong, R. A., Perez, K. M., Yoshida, T., and Zweerink, J.
- Subjects
Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The General AntiParticle Spectrometer experiment (GAPS) is foreseen to carry out a dark matter search using low-energy cosmic ray antideuterons at stratospheric altitudes with a novel detection approach. A prototype flight from Taiki, Japan was carried out in June 2012 to prove the performance of the GAPS instrument subsystems (Lithium-drifted Silicon tracker and time-of-flight) and the thermal cooling concept as well as to measure background levels. The flight was a success and the stable flight operation of the GAPS detector concept was proven. During the flight about $10^6$ charged particle triggers were recorded, extensive X-ray calibrations of the individual tracker modules were performed by using an onboard X-ray tube, and the background level of atmospheric and cosmic X-rays was measured. The behavior of the tracker performance as a function of temperature was investigated. The tracks of charged particle events were reconstructed and used to study the tracking resolution, the detection efficiency of the tracker, and coherent X-ray backgrounds. A timing calibration of the time-of-flight subsystem was performed to measure the particle velocity. The flux as a function of flight altitude and as a function of velocity was extracted taking into account systematic instrumental effects. The developed analysis techniques will form the basis for future flights., Comment: accepted for publication by Astroparticle Physics: 33 pages, 36 figures
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- 2013
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16. A Measurement of Atomic X-ray Yields in Exotic Atoms and Implications for an Antideuteron-Based Dark Matter Search
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Aramaki, T., Chan, S. K., Craig, W. W., Fabris, L., Gahbauer, F., Hailey, C. J., Koglin, J. E., Madden, N., Mori, K., Yu, H. T., and Ziock, K. P.
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Cosmology and Extragalactic Astrophysics ,Physics - Instrumentation and Detectors - Abstract
The General AntiParticle Spectrometer (GAPS) is a novel approach for the indirect dark matter search that exploits cosmic antideuterons. GAPS utilizes a distinctive detection method using atomic X-rays and charged particles from the exotic atom as well as the timing, stopping range and dE/dX energy deposit of the incoming particle, which provides excellent antideuteron identification. In anticipation of a future balloon experiment, an accelerator test was conducted in 2004 and 2005 at KEK, Japan, in order to prove the concept and to precisely measure the X-ray yields of antiprotonic exotic atoms formed with different target materials [1]. The X-ray yields of the exotic atoms with Al and S targets were obtained as ~ 75%, which are higher than were previously assumed in [2]. A simple, but comprehensive cascade model has been developed not only to evaluate the measurement results but also to predict the X-ray yields of the exotic atoms formed with any materials in the GAPS instrument. The cascade model is extendable to any kind of exotic atom (any negatively charged cascading particles with any target materials), and it was compared and validated with other experimental data and cascade models for muonic and antiprotonic exotic atoms. The X-ray yields of the antideuteronic exotic atoms are predicted with a simple cascade model and the sensitivity for the GAPS antideuteron search was estimated for the proposed long duration balloon program [3], which suggests that GAPS has a strong potential to detect antideuterons as a dark matter signature. A GAPS prototype flight (pGAPS) was launched successfully from the JAXA/ISAS balloon facility in Hokkaido, Japan in summer 2012 [4, 5] and a proposed GAPS science flight is to fly from Antarctica in the austral summer of 2017-2018., Comment: 17 pages, 25 figures, accepted in "Astroparticle Physics"
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- 2013
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17. The Prototype GAPS (pGAPS) Experiment
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Mognet, S. A. I., Aramaki, T., Bando, N., Boggs, S. E., von Doetinchem, P., Fuke, H., Gahbauer, F. H., Hailey, C. J., Koglin, J. E., Madden, N., Mori, K., Okazaki, S., Ong, R. A., Perez, K. M., Tajiri, G., Yoshida, T., and Zweerink, J.
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Astrophysics - Instrumentation and Methods for Astrophysics ,Physics - Instrumentation and Detectors - Abstract
The General Antiparticle Spectrometer (GAPS) experiment is a novel approach for the detection of cosmic ray antiparticles. A prototype GAPS experiment (pGAPS) was successfully flown on a high-altitude balloon in June of 2012. The goals of the pGAPS experiment were: to test the operation of lithium drifted silicon (Si(Li)) detectors at balloon altitudes, to validate the thermal model and cooling concept needed for engineering of a full-size GAPS instrument, and to characterize cosmic ray and X-ray backgrounds. The instrument was launched from the Japan Aerospace Exploration Agency's (JAXA) Taiki Aerospace Research Field in Hokkaido, Japan. The flight lasted a total of 6 hours, with over 3 hours at float altitude (~33 km). Over one million cosmic ray triggers were recorded and all flight goals were met or exceeded., Comment: 37 pages, 25 figures
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- 2013
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18. Measurement of the Scintillation Yield of Low-Energy Electrons in Liquid Xenon
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Aprile, E., Budnik, R., Choi, B., Contreras, H. A., Giboni, K. -L., Goetzke, L. W., Koglin, J. E., Lang, R. F., Lim, K. E., Fernandez, A. J. Melgarejo, Persiani, R., Plante, G., and Rizzo, A.
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Astrophysics - Instrumentation and Methods for Astrophysics ,Physics - Instrumentation and Detectors - Abstract
We have measured the energy dependence of the liquid xenon (LXe) scintillation yield of electrons with energy between 2.1 and 120.2keV, using the Compton coincidence technique. A LXe scintillation detector with a very high light detection efficiency was irradiated with 137Cs {\gamma} rays and the energy of the Compton-scattered {\gamma} rays was measured with a high-purity germanium (HPGe) detector placed at different scattering angles. The excellent energy resolution of the HPGe detector allows the selection of events with Compton electrons of known energy in the LXe detector. We find that the scintillation yield initially increases as the electron energy decreases from 120 keV to about 60keV but then decreases by about 30% from 60keV to 2keV. The measured scintillation yield was also measured with conversion electrons from the 32.1 keV and 9.4 keV transitions of the 83mKr isomer, used as an internal calibration source. We find that the scintillation yield of the 32.1 keV transition is compatible with that obtained from the Compton coincidence measurement. On the other hand, the yield for the 9.4keV transition is much higher than that measured for a Compton electron of the same energy. We interpret the enhancement in the scintillation yield as due to the enhanced recombination rate in the presence of Xe ions left from the 32.1 keV transition, which precedes the 9.4 keV one by 220 ns, on average., Comment: 14 pages, 8 figures
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- 2012
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19. The General Antiparticle Spectrometer (GAPS) - Hunt for dark matter using low-energy antideuterons
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von Doetinchem, Ph., Aramaki, T., Boggs, St., Craig, W., Fuke, H., Gahbauer, F., Hailey, Ch., Koglin, J., Madden, N., Mognet, I., Mori, K., Ong, R., Yoshida, T., Zhang, T., and Zweerink, J.
- Subjects
Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The GAPS experiment is foreseen to carry out a dark matter search using a novel detection approach to detect low-energy cosmic-ray antideuterons. The theoretically predicted antideuteron flux resulting from secondary interactions of primary cosmic rays with the interstellar medium is very low. So far not a single cosmic antideuteron has been detected by any experiment, but well-motivated theories beyond the standard model of particle physics, e.g., supersymmetry or universal extra dimensions, contain viable dark matter candidates, which could led to a significant enhancement of the antideuteron flux due to self-annihilation of the dark matter particles.This flux contribution is believed to be especially large at small energies, which leads to a high discovery potential for GAPS. GAPS is designed to achieve its goals via a series of ultra-long duration balloon flights at high altitude in Antarctica, starting in 2014. The detector itself will consist of 13 planes of Si(Li) solid state detectors and a time of flight system. The low-energy antideuterons (< 0.3 GeV/n) will be slowed down in the Si(Li) material, replace a shell electron, and form an excited exotic atom. The atom will be deexcited by characteristic x-ray transitions and will end its life by forming an annihilation pion star. This unique event structure will allow for nearly background free detection. To prove the performance of the different detector components at stratospheric altitudes, a prototype flight will be conducted in 2011 from Taiki, Japan., Comment: 7 pages, 4 figures, conference proceedings of IDM2010 - identification of dark matter 2010 (submitted)
- Published
- 2010
20. Quantitative spatiotemporal density evolution of aluminum heated purely by monochromatic electrons.
- Author
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Coleman, J. E., Koglin, J. E., Morris, H. E., Ramey, N. B., and Offermann, D. T.
- Abstract
A spatially resolved air-wedge shearing interferometer and shadowgraph diagnostic provides measurements of electron density with a resolution of ∼ 40 μ m. A ∼ 100-ns-long, monoenergetic electron bunch at 19.8 MeV and a current of 1.4 kA (8.5 × 10 14 e −) heats 100- μ m-thick aluminum (Al) foils in a 1-mm-spot to T e ∼ 1 eV. A 5-ns-long, ∼ 60 mJ, frequency doubled Nd:YAG laser probes the dense Al plasma. Electron densities up to 10 20 cm − 3 are resolved; the maximum resolvable density is limited by opacity, transmission, and spatial fringe density achievable with the detector. This diagnostic provides measurements of the total phase shift, transmission, and electron density. Several measurements at different time slices provide the ability to determine the velocity of the leading edge of the shadowgraph and compare it to the motion of different density shells. These measurements are also compared to radiation hydrodynamics simulations. A rough quantitative agreement is shown between the hydro simulations and the measurements; there are differences in the exact density distributions. [ABSTRACT FROM AUTHOR]
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- 2022
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21. Accelerator Testing of the General Antiparticle Spectrometer, a Novel Approach to Indirect Dark Matter Detection
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Hailey, C J, Aramaki, T, Craig, W W, Fabris, L, Gahbauer, F, Koglin, J E, Madden, N, Mori, K, Yu, H T, and Ziock, K P
- Subjects
Astrophysics - Abstract
We report on recent accelerator testing of a prototype general antiparticle spectrometer (GAPS). GAPS is a novel approach for indirect dark matter searches that exploits the antideuterons produced in neutralino-neutralino annihilations. GAPS captures these antideuterons into a target with the subsequent formation of exotic atoms. These exotic atoms decay with the emission of X-rays of precisely defined energy and a correlated pion signature from nuclear annihilation. This signature uniquely characterizes the antideuterons. Preliminary analysis of data from a prototype GAPS in an antiproton beam at the KEK accelerator in Japan has confirmed the multi-X-ray/pion star topology and indicated X-ray yields consistent with prior expectations. Moreover our success in utilizing solid rather than gas targets represents a significant simplification over our original approach and offers potential gains in sensitivity through reduced dead mass in the target area., Comment: 18 pages, 9 figures, submitted to JCAP
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- 2005
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22. Design, Commissioning and Performance of the PIBETA Detector at PSI
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Frlez, E., Pocanic, D., Assamagan, K. A., Bagaturia, Yu., Baranov, V. A., Bertl, W., Broennimann, Ch., Bychkov, M. A., Crawford, J. F., Daum, M., Fluegel, Th., Frosch, R., Horisberger, R., Kalinnikov, V. A., Karpukhin, V. V., Khomutov, N. V., Koglin, J. E., Korenchenko, A. S., Korenchenko, S. M., Kozlowski, T., Krause, B., Kravchuk, N. P., Kuchinsky, N. A., Li, W., Lawrence, D. W., Minehart, R. C., Mzhavia, D., Obermeier, H., Renker, D., Ritchie, B. G., Ritt, S., Sakhelashvili, T., Schnyder, R., Sidorkin, V. V., Slocum, P. L., Smith, L. C., Soic, N., Stephens, W. A., Supek, I., Tsamalaidze, Z., VanDevender, B. A., Wang, Y., Wirtz, H. -P., and Ziock, K. O. H.
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High Energy Physics - Experiment ,Physics - Instrumentation and Detectors - Abstract
We describe the design, construction and performance of the PIBETA detector built for the precise measurement of the branching ratio of pion beta decay, pi+ -> pi0 e+ nu, at the Paul Scherrer Institute. The central part of the detector is a 240-module spherical pure CsI calorimeter covering 3*pi sr solid angle. The calorimeter is supplemented with an active collimator/beam degrader system, an active segmented plastic target, a pair of low-mass cylindrical wire chambers and a 20-element cylindrical plastic scintillator hodoscope. The whole detector system is housed inside a temperature-controlled lead brick enclosure which in turn is lined with cosmic muon plastic veto counters. Commissioning and calibration data were taken during two three-month beam periods in 1999/2000 with pi+ stopping rates between 1.3*E3 pi+/s and 1.3*E6 pi+/s. We examine the timing, energy and angular detector resolution for photons, positrons and protons in the energy range of 5-150 MeV, as well as the response of the detector to cosmic muons. We illustrate the detector signatures for the assorted rare pion and muon decays and their associated backgrounds., Comment: 117 pages, 48 Postscript figures, 5 tables, Elsevier LaTeX, submitted to Nucl. Instrum. Meth. A
- Published
- 2003
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23. Development of the Gaseous Antiparticle Spectrometer for Space-based Antimatter Detection
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Hailey, C. J., Craig, W. W., Harrison, F. A., Hong, J., Mori, K., Koglin, J., Yu, H. T., and Ziock, K. P.
- Subjects
Astrophysics - Abstract
We report progress in developing a novel antimatter detection scheme. The gaseous antiparticle spectrometer (GAPS) identifies antimatter through the characteristic X-rays emitted by antimatter when it forms exotic atoms in gases. The approach provides large area and field of view, and excellent background rejection capability. If the GAPS concept is successfully demonstrated, then it would be an ideal candidate for space-based, indirect dark matter searches. GAPS can detect antideuterons produced in neutralino annihilations. A modest GAPS experiment can detect the neutralino for all minimal SUSY models in which the neutralino mass is in the 50-350 GeV mass range. Underground searches, by contrast, are only sensitive to about 1/2 the SUSY parameter space in this mass range., Comment: 6 pages, 3 figures, accepted for publication in Nuclear Instruments and Methods B: Proceedings of the LEAP03
- Published
- 2003
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24. The KARMEN Time Anomaly: Search for a Neutral Particle of Mass 33.9 MeV in Pion Decay
- Author
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Daum, M., Janousch, M., Kettle, P-R., Koglin, J., Pocanic, D., Schotmueller, J., Wigger, C., and Zhao, Z. G.
- Subjects
High Energy Physics - Experiment - Abstract
We have searched for the pion decay pi^+ --> mu^+ X, where X is a neutral particle of mass 33.905 MeV. This process was suggested by the KARMEN Collaboration to explain an anomaly in their observed time distribution of neutrino induced reactions. Having measured the muon momentum spectrum of charged pions decaying in flight, we find no evidence for this process and place an upper limit on the branching fraction eta leq 6.0 * 10^{-10} of such a decay at a 95% confidence level., Comment: 17 pages including 4 for figures
- Published
- 2000
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25. The hyperion particle-γ detector array
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Hughes, R.O., Harke, J.T., Casperson, R.J., Ota, S., Fisher, S., Parker, J., Beausang, C.W., Dag, M., Humby, P., Koglin, J., McCleskey, E., McIntosh, A.B., Saastamoinen, A., Tamashiro, A.S., Wilson, E., and Wu, T.C.
- Published
- 2017
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26. Femtosecond response of polyatomic molecules to ultra-intense hard X-rays
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Rudenko, A., Inhester, L., Hanasaki, K., Li, X., Robatjazi, S. J., Erk, B., Boll, R., Toyota, K., Hao, Y., Vendrell, O., Bomme, C., Savelyev, E., Rudek, B., Foucar, L., Southworth, S. H., Lehmann, C. S., Kraessig, B., Marchenko, T., Simon, M., Ueda, K., Ferguson, K. R., Bucher, M., Gorkhover, T., Carron, S., Alonso-Mori, R., Koglin, J. E., Correa, J., Williams, G. J., Boutet, S., Young, L., Bostedt, C., Son, S.-K., Santra, R., and Rolles, D.
- Subjects
X-rays -- Physiological aspects ,Femtosecond lasers -- Physiological aspects ,Environmental issues ,Science and technology ,Zoology and wildlife conservation - Abstract
Author(s): A. Rudenko (corresponding author) [1]; L. Inhester [2, 3]; K. Hanasaki [2, 3, 4]; X. Li [1]; S. J. Robatjazi [1]; B. Erk [5]; R. Boll [5, 6]; K. [...]
- Published
- 2017
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27. 44 Ti gamma-ray emission lines from SN1987A reveal an asymmetric explosion
- Author
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Boggs, S. E., Harrison, F. A., Miyasaka, H., Grefenstette, B. W., Zoglauer, A., Fryer, C. L., Reynolds, S. P., Alexander, D. M., An, H., Barret, D., Christensen, F. E., Craig, W. W., Forster, K., Giommi, P., Hailey, C. J., Hornstrup, A., Kitaguchi, T., Koglin, J. E., Madsen, K. K., Mao, P. H., Mori, K., Perri, M., Pivovaroff, M. J., Puccetti, S., Rana, V., Stern, D., Westergaard, N. J., and Zhang, W. W.
- Published
- 2015
28. Temperature and Density Measurements of an Optically Thick, Dense Aluminum Plasma Heated by Monochromatic Electrons
- Author
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Ramey, N. B., primary, Coleman, J. E., additional, Hakel, P., additional, Morris, H. E., additional, Fontes, C. J., additional, Colgan, J., additional, Koglin, J. E., additional, Gilgenbach, R. M., additional, and McBride, R. D., additional
- Published
- 2022
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29. Zerebrales natriuretisches Peptid — neuer Parameter zur Kandidatenselektion
- Author
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Koglin, J., Rüter, Florian, editor, von Scheidt, Wolfgang, editor, Buser, Peter, editor, and Zerkowski, Hans-Reinhard, editor
- Published
- 2002
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30. THE NuSTAR Hard X-Ray Survey of the Norma Arm Region
- Author
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Fornasini, Francesca M, Tomsick, John A, Hong, Jaesub, Gotthelf, Eric V, Bauer, Franz, Rahoui, Farid, Stern, Daniel K, Bodaghee, Arash, Chiu, Jeng-Lun, Clavel, Maïca, Corral-Santana, Jesús, Hailey, Charles J, Krivonos, Roman A, Mori, Kaya, Alexander, David M, Barret, Didier, Boggs, Steven E, Christensen, Finn E, Craig, William W, Forster, Karl, Giommi, Paolo, Grefenstette, Brian W, Harrison, Fiona A, Hornstrup, Allan, Kitaguchi, Takao, Koglin, J. E, Madsen, Kristin K, Mao, Peter H, Miyasaka, Hiromasa, Perri, Matteo, Pivovaroff, Michael J, Puccetti, Simonetta, Rana, Vikram, Westergaard, Niels J, and Zhang, William W
- Subjects
Astrophysics - Abstract
We present a catalog of hard X-ray sources in a square-degree region surveyed by the Nuclear Spectroscopic Telescope Array (NuSTAR) in the direction of the Norma spiral arm. This survey has a total exposure time of 1.7 Ms, and the typical and maximum exposure depths are 50 ks and 1 Ms, respectively. In the area of deepest coverage, sensitivity limits of 5 x 10(exp -14) and 4 x 10(exp -14) ergs/s/sq cm in the 3-10 and 10-20 keV bands, respectively, are reached. Twenty-eight sources are firmly detected, and 10 are detected with low significance; 8 of the 38 sources are expected to be active galactic nuclei. The three brightest sources were previously identified as a low-mass X-ray binary, high-mass X-ray binary, and pulsar wind nebula. Based on their X-ray properties and multiwavelength counterparts, we identify the likely nature of the other sources as two colliding wind binaries, three pulsar wind nebulae, a black hole binary, and a plurality of cataclysmic variables (CVs). The CV candidates in the Norma region have plasma temperatures of approx. 10-20 keV, consistent with the Galactic ridge X-ray emission spectrum but lower than the temperatures of CVs near the Galactic center. This temperature difference may indicate that the Norma region has a lower fraction of intermediate polars relative to other types of CVs compared to the Galactic center. The NuSTAR logN-logS distribution in the 10-20keV band is consistent with the distribution measured by Chandra at 2-10 keV if the average source spectrum is assumed to be a thermal model with kT approx. =15 keV, as observed for the CV candidates.
- Published
- 2017
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31. The NuSTAR Extragalactic Surveys: The Number Counts Of Active Galactic Nuclei And The Resolved Fraction Of The Cosmic X-ray Background
- Author
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Harrison, F. A, Aird, J, Civano, F, Lansbury, G, Mullaney, J. R, Ballentyne, D. R, Alexander, D. M, Stern, D, Ajello, M, Barret, D, Bauer, F. E, Balokovic, M, Brandt, W. N, Brightman, M, Boggs, S. E, Christensen, F. E, Comastri, A, Craig, W. W, Del Moro, A, Forster, K, Gandhi, P, Giommi, P, Grefenstette, B. W, Hailey, C. J, Hickox, R. C, Hornstrup, A, Kitaguchi, T, Koglin, J, Luo, B, Madsen, K. K, Mao, P. H, Miyasaka, H, Mori, K, Perri, M, Pivovaroff, M, Puccetti, S, Rana, V, Treister, E, Walton, D, Westergaard, N. J, Wik, D, Zappacosta, L, Zhang, W. W, and Zoglauer, A
- Subjects
Astrophysics - Abstract
We present the 3-8 kiloelectronvolts and 8-24 kiloelectronvolts number counts of active galactic nuclei (AGNs) identified in the Nuclear Spectroscopic Telescope Array (NuSTAR) extragalactic surveys. NuSTAR has now resolved 33 percent -39 percent of the X-ray background in the 8-24 kiloelectronvolts band, directly identifying AGNs with obscuring columns up to approximately 10 (exp 25) per square centimeter. In the softer 3-8 kiloelectronvolts band the number counts are in general agreement with those measured by XMM-Newton and Chandra over the flux range 5 times 10 (exp -15) less than or approximately equal to S (3-8 kiloelectronvolts) divided by ergs per second per square centimeter less than or approximately equal to 10 (exp -12) probed by NuSTAR. In the hard 8-24 kiloelectronvolts band NuSTAR probes fluxes over the range 2 times 10 (exp -14) less than or approximately equal to S (8-24 kiloelectronvolts) divided by ergs per second per square centimeter less than or approximately equal to 10 (exp -12), a factor approximately 100 times fainter than previous measurements. The 8-24 kiloelectronvolts number counts match predictions from AGN population synthesis models, directly confirming the existence of a population of obscured and/or hard X-ray sources inferred from the shape of the integrated cosmic X-ray background. The measured NuSTAR counts lie significantly above simple extrapolation with a Euclidian slope to low flux of the Swift/BAT15-55 kiloelectronvolts number counts measured at higher fluxes (S (15-55 kiloelectronvolts) less than or approximately equal to 10 (exp -11) ergs per second per square centimeter), reflecting the evolution of the AGN population between the Swift/BAT local (redshift is less than 0.1) sample and NuSTAR's redshift approximately equal to 1 sample. CXB (Cosmic X-ray Background) synthesis models, which account for AGN evolution, lie above the Swift/BAT measurements, suggesting that they do not fully capture the evolution of obscured AGNs at low redshifts
- Published
- 2016
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32. Near Field Optics and Scanning Near Field Optical Microscopy
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Fischer, U. C., Koglin, J., Naber, A., Raschewski, A., Tiemann, R., Fuchs, H., Ducloy, Martial, editor, and Bloch, Daniel, editor
- Published
- 1996
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33. 6 NM Lateral Resolution in Scanning Near Field Optical Microscopy with the Tetrahedral Tip
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Koglin, J., Fischer, U. C., Fuchs, H., Nieto-Vesperinas, M., editor, and García, N., editor
- Published
- 1996
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34. 239Pu(n, 2n) and 241Pu(n, 2n) surrogate cross section measurements using NeutronSTARS
- Author
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Burke, J., primary, Alan, B., additional, Akindele, O., additional, Casperson, R., additional, Hughes, R., additional, Koglin, J., additional, Tamashiro, A., additional, Kolos, K., additional, Norman, E., additional, Saastamoinen, A., additional, Padilla, A., additional, and Fisher, S., additional
- Published
- 2017
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35. The Tetrahedral Tip as a Probe for Scanning Near-Field Optical and for Scanning Tunneling Microscopy
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Koglin, J., Fischer, U. C., Brzoska, K. D., Göhde, W., Fuchs, H., Marti, Othmar, editor, and Möller, Rolf, editor
- Published
- 1995
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36. Anomalous two-photon Compton scattering
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Kettle, B, primary, Aquila, A, additional, Boutet, S, additional, Bucksbaum, P H, additional, Carini, G, additional, Feng, Y, additional, Gamboa, E, additional, Ghimire, S, additional, Glenzer, S, additional, Hart, P, additional, Hastings, J B, additional, Henighan, T, additional, Hunter, M, additional, Koglin, J, additional, Kozina, M, additional, Liu, H, additional, MacDonald, M J, additional, Trigo, M, additional, Reis, D A, additional, and Fuchs, M, additional
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- 2021
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37. Pulse Energy and Pulse Duration Effects in the Ionization and Fragmentation of Iodomethane by Ultraintense Hard X Rays
- Author
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Li, X., primary, Inhester, L., additional, Robatjazi, S. J., additional, Erk, B., additional, Boll, R., additional, Hanasaki, K., additional, Toyota, K., additional, Hao, Y., additional, Bomme, C., additional, Rudek, B., additional, Foucar, L., additional, Southworth, S. H., additional, Lehmann, C. S., additional, Kraessig, B., additional, Marchenko, T., additional, Simon, M., additional, Ueda, K., additional, Ferguson, K. R., additional, Bucher, M., additional, Gorkhover, T., additional, Carron, S., additional, Alonso-Mori, R., additional, Koglin, J. E., additional, Correa, J., additional, Williams, G. J., additional, Boutet, S., additional, Young, L., additional, Bostedt, C., additional, Son, S.-K., additional, Santra, R., additional, Rolles, D., additional, and Rudenko, A., additional
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- 2021
- Full Text
- View/download PDF
38. SUPERNOVAE: 44Ti gamma-ray emission lines from SN1987A reveal an asymmetric explosion
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Boggs, S. E., Harrison, F. A., Miyasaka, H., Grefenstette, B. W., Zoglauer, A., Fryer, C. L., Reynolds, S. P., Alexander, D. M., An, H., Barret, D., Christensen, F. E., Craig, W. W., Forster, K., Giommi, P., Hailey, C. J., Hornstrup, A., Kitaguchi, T., Koglin, J. E., Madsen, K. K., Mao, P. H., Mori, K., Perri, M., Pivovaroff, M. J., Puccetti, S., Rana, V., Stern, D., Westergaard, N. J., and Zhang, W. W.
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- 2015
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39. Ti-44 Gamma-Ray Emission Lines from SN1987A Reveal an Asymmetric Explosion
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Boggs, S. E, Harrison, F. A, Miyasaka, H, Grefenstette, B. W, Zoglauer, A, Fryer, C. L, Reynolds, S. P, Alexander, D. M, An, H, Barret, D, Christensen, F. E, Craig, W. W, Forster, K, Giommi, P, Hailey, C. J, Hornstrup, A, Kitaguchi, T, Koglin, J. E, Madsen, K. K, and Zhang, W. W
- Subjects
Astrophysics - Abstract
In core-collapse supernovae, titanium-44 (Ti-44) is produced in the innermost ejecta, in the layer of material directly on top of the newly formed compact object. As such, it provides a direct probe of the supernova engine. Observations of supernova 1987A (SN1987A) have resolved the 67.87- and 78.32-kilo-electron volt emission lines from decay of Ti-44 produced in the supernova explosion. These lines are narrow and redshifted with a Doppler velocity of ~700 kilometers per second, direct evidence of large-scale asymmetry in the explosion.
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- 2015
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- View/download PDF
40. Asymmetries in core-collapse supernovae from maps of radioactive 44Ti in Cassiopeia A
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Grefenstette, B. W., Harrison, F. A., Boggs, S. E., Reynolds, S. P., Fryer, C. L., Madsen, K. K., Wik, D. R., Zoglauer, A., Ellinger, C. I., Alexander, D. M., An, H., Barret, D., Christensen, F. E., Craig, W. W., Forster, K., Giommi, P., Hailey, C. J., Hornstrup, A., Kaspi, V. M., Kitaguchi, T., Koglin, J. E., Mao, P. H., Miyasaka, H., Mori, K., Perri, M., Pivovaroff, M. J., Puccetti, S., Rana, V., Stern, D., Westergaard, N. J., and Zhang, W. W.
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- 2014
- Full Text
- View/download PDF
41. Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction
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Armstrong PW, Pieske B, Anstrom KJ, Ezekowitz J, Hernandez AF, Butler J, Lam CSP, Ponikowski P, Voors AA, Jia G, McNulty SE, Patel MJ, Roessig L, Koglin J, O'Connor CM, and VICTORIA Study Group
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animal structures - Abstract
The effect of vericiguat, a novel oral soluble guanylate cyclase stimulator, in patients with heart failure and reduced ejection fraction who had recently been hospitalized or had received intravenous diuretic therapy is unclear.
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- 2020
42. Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes
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Green JB, Bethel MA, Armstrong PW, Buse JB, Engel SS, Garg J, Josse R, Kaufman KD, Koglin J, Korn S, Lachin JM, McGuire DK, Pencina MJ, Standl E, Stein PP, Suryawanshi S, Van de Werf F, Peterson ED, Holman RR, Josse RG, Califf RM, Goldstein BJ, Shapiro DR, Silverman R, Bethel A, Green J, Hayden S, Hannan K, Quintero K, Rorick T, Berdan L, Leloudis D, Califf S, Wilson M, McFarron D, Trollinger K, Pesarchick J, Eskenazi L, Campbell C, Townes O, Tolsma D, Keenan J, Milton J, Athwal R, Darbyshire J, Doran Z, Kennedy I, Gregory V, Lokhnygina Y, Prather K, Wolfley A, Usman M, Tajjar A, Gray R, Pfeffer MA, Gerstein HC, Groop L, McMurray JJ, Pocock SJ, Clayton T, Sinay I, Brieger D, Stranks S, Scheen A, Lopes R, Tankova T, Hramiak I, Grado CR, Wenying Y, Ge J, Aschner P, Skrha J, Ambos A, Strandberg T, Travert F, Hanefeld M, Riefflin A, Chan JC, Ofner P, Reddy NK, Christopher J, Mathur A, Arambam P, Mittal S, Manchanda M, Wainstein J, Ambrosio G, Pirags V, Jakuboniene N, Mohamed M, Scott R, White H, Cornel J, Halvorsen S, Tykarski A, Veresiu IA, Dreval AV, Misinkova I, Tai E, Krahulec B, Distiller L, Park Y, Rovira A, Alversson M, Chuang LM, Delibasi T, Adler A, Rodbard HW, Marre M, Goff D, Chacra A, DeVore A, Beaven A, Shah B, Hirsch B, Batch B, Bushnell C, Patel C, Melloni C, Henshaw C, Kong D, Bernecki G, Tillman H, Kang HJ, Hawes J, Strickler J, Piccini J, Wilder J, Alexander K, Mahaffey K, Patel K, Hyland K, Newby K, Jackson L, Cooper L, Armaganijan L, Szczeh L, Koshizaka M, Roe M, Morse M, Guimaraes P, Hess P, Tricoci P, Mehta R, Mathews R, Kociol R, Harrison R, Mentz R, Pokorney S, Leblanc T, Lazzarini V, Eapen Z, Truffa A, Fosbol E, Brito F, Katz M, Bahit M, Santos M, Barros P, Bernardez S, Alvarisqueta AF, Arias P, Cagide AL, Calella PR, Cantero MC, Canella JP, Cipullo MA, de Loredo L, Gelersztein ES, Gorban de Lapertosa SB, Klyver MI, Maffei LE, Maldonado N, Oviedo AI, Piskorz DL, Ridruejo MC, Saavedra SS, Sessa HA, Sinay IR, Sposetti GD, Ulla MR, Vico ML, Waitman JN, Binnekamp M, Carroll P, Cheung W, Colman P, Davis T, De Looze F, dEmden M, Fulcher G, Gerstman M, Hamilton A, Lehman S, Moses R, Proietto J, Roberts A, Shaw J, Simpson R, Sinha A, Tan Y, Topliss D, Vora P, Waites J, Crenier L, Descamps O, Keymeulen B, Mathieu C, Nobels F, Van den Bruel A, Van Gaal L, Borges JL, Costa e Forti A, Eliaschewitz FG, Felício JS, Griz LH, Hissa MN, Leite S, Panarotto D, Pimentel Filho P, Rassi N, Saraiva JK, Sgarbi JA, Silva RP, Tambascia M, Weber Silva DM, Bobeva R, Bostandzhieva R, Cinlikov I, Georgieva M, Iliev D, Ilieva E, Kovacheva S, Liubenova L, Nikitov Z, SHeinikova G, Slavcheva A, Spasova V, Temelkova-Kurktschiev T, Velichka D, Yakov A, Carpentier A, Chiasson JL, Constance C, Dumas R, Filteau P, Garceau C, Huynh T, Kaiser S, Kornder J, Leiter L, Mereu L, Miller D, Pandey S, Punthakee Z, Rabasa-Lhoret R, Robitaille Y, Saunders K, Sigal R, Sigalas J, Vizel S, Weisnagel S, Woo V, Yale JF, Yared K, Zinman B, Bunster Balocchi LB, Escobar Cerda EE, Garces Flores EE, Lanas Zanetti FT, Larrazabal Miranda Adel P, Morales Alvarado JM, Olivares Cañon CM, Potthoff Cárdenas SH, Raffo Grado CA, Rodriguez Venegas ME, Saavedra Gajardo VA, Westerberg Maldonado BH, Chen LL, Dong J, Guo X, Li QM, Shi B, Tang XL, Yang T, Yang WY, Zheng SX, Aschner Montoya P, Botero Lopez R, Coronel Arroyo JA, Cure CA, Gómez Medina AM, Molina DI, Perez Amador GA, Reyes Rincon A, Urina Triana MA, Valenzuela Rincon A, Vélez Pelaez S, Yupanqui Lozno H, Brabec T, Brychta T, Hasalova Zapletalova J, Havelkova J, Hejnicova K, Hola O, Hornackova M, Hrdina T, Kafkova D, Kellnerova I, Krystl T, Kutejova V, Mikulkova I, Nevrla J, Pantlikova C, Petr M, Racicka E, Sarbochova R, Smolenakova K, Turcinek R, Urbancova K, Vejvodova J, Vondrakova M, Zachoval R, Alt I, Kaasik Ü, Kiiroja K, Lanno R, Märtsin K, Past M, Vides H, Viitas L, Kantola I, Nieminen S, Perhonen M, Strand J, Valle T, Clergeot A, Couffinhal T, Courreges JP, Gouet D, Moulin P, Ziegler O, Badenhoop K, Behnke T, Bender G, Braun M, Dshabrailov J, Hamann A, Himpel-Boenninghoff A, Kamke W, Kasperk C, Luedemann J, Mayr P, Merkel M, Oerter EM, Ohlow MA, Ott P, Overhoff U, Paschen B, Remppis R, Rose L, Schumm-Draeger PM, Segiet T, Strotmann HJ, Stuchlik G, Stürmer W, Thinesse-Mallwitz M, Tytko A, Wendisch U, Wurziger J, Ho AY, Kam G, Kong AP, Lam YY, Lau EY, Lee S, Siu SC, Tomlinson B, Tsang CC, Yeung VT, Dezső E, Dudás M, Földesi I, Fülöp T, Késmárki N, Koranyi L, Nagy K, Oroszlán T, Pécsvárady Z, Ples Z, Taller A, Agarwal P, Ambulkar S, Aravind S, Balaji V, Kalra S, Kesavadev J, Kudalkar H, Kumar A, Misra A, Mithal A, Mohan V, Pitale S, Ramu M, Reddy N, Shah S, Shamanna P, Sharda A, Sharma A, Shunmugavelu M, Srikanta S, Suryaprakash G, Abramov G, Adawi F, Bashkin A, Darawsha M, Fuchs S, Harman-Boehm I, Hayek T, Jaffe A, Knobler H, Minuchin O, Mosseri M, Shechter M, Shimon I, Stern N, Tsur A, Vishlitzky V, Alfonsi F, Cavalot F, Del Vecchio L, Frisinghelli A, Gambardella S, Lauro D, Lembo G, Leotta S, Mondillo S, Novo S, Pedrinelli R, Piatti P, Salvioni A, Tritto I, Zavaroni DZ, Ahn KJ, Choi KM, Chung C, Han SJ, Kim DM, Kim IJ, Kim MH, Lee IK, Nam M, Park IeB, Park KS, Park TS, Rhee EJ, Yoo SJ, Andersone I, Balode A, Eglite R, Gersamija A, Kakurina N, Jegere B, Leitane I, Pastare S, Stalte V, Teterovska D, Baltramonaitiene K, Barsiene L, Ceponis J, Lasiene J, Levinger A, Sirutaviciene A, Sulskiene M, Urbanaviciene L, Valius L, Varanauskiene E, Velickiene D, Mahendran KA, Abu Hassan MR, Aziz NA, Hussein Z, Ismail IS, Kamaruddin NA, Nordin Z, Nayar SK, Ramanathan GR, Sothiratnam R, Beijerbacht H, Breedveld R, Cornel JH, Den Hartog F, Hermans W, Kietselaer B, Kooy A, Lenderink T, Nierop P, Remmen J, Rojas Lingan G, Ronner E, Van der Heijden R, Van Hessen M, van Kempen W, Voors-Pette C, Westendorp I, Baker J, Benatar J, Cutfield R, Krebs J, Leikis R, Lunt H, Manning P, Williams M, Birkeland K, Claudi T, Istad H, Karlsson T, Ossum Gronert J, Arciszewska M, Artemiuk E, Blach E, Blicharski T, Cypryk K, Dabrowska M, Górny G, Górska M, Jakubowska I, Jazwinska-Tarnawska E, Karczmarczyk A, Kitowska-Koterla J, Koltowski L, Krzyzagorska E, Pasternak D, Pentela-Nowicka J, Piesiewicz W, Przekwas-Jaruchowska M, Rajzer M, Salamon-Ferenc A, Sawicki A, Skowron T, Śmiałowski A, Albota A, Alexandru C, Crisan C, Dumitrescu A, Ferariu IE, Lupusoru DA, Munteanu M, Negru D, Nicolau A, Pintiliei E, Popescu A, Serban G, Voitec M, Babenko A, Barbarash O, Bondar I, Chizhov P, Demin A, Dora S, Dreval A, Ershova O, Gratsiansky N, Ketova G, Kotelnikov M, Levashov S, Morugova T, Mustafina S, Pekarskiy S, Raskina T, Rechkova E, Samoylova Y, Sazonova O, Sherenkov A, Shilkina N, Stetsyuk O, Tretyakova T, Turova E, Valeeva F, Zadionchenko V, Dalan R, Tan RS, Tay L, Buganova I, Fabry J, Jan C, Toserova E, Zak R, Zimanova J, Badat A, Bester F, Burgess L, De Jong D, Ellis G, Fouche L, Govender P, Govind U, Naidoo V, Nieuwoudt G, Nortje H, Rheeder P, Robertson L, Siddique N, Stapelberg AM, Trinder Y, Van Der Merwe A, Van Zyl L, Viljoen M, Wilhase A, Botella M, Civeira Murillo F, de Teresa L, Del Cañizo FJ, Extremera BG, Gimeno EJ, Martin-Hidalgo A, Morales C, Nubiola A, Tinahones Madueño F, Tranche S, Trescolí Serrano C, Alvarsson M, Eizyk E, Gillblad A, Johansson P, Löndahl M, Ohlsson-Önerud Å, Rautio A, Sundström U, Torstensson I, Chen JF, Chou CW, Ho LT, Hsieh IC, Huang BH, Huang CL, Huang CN, Lai WT, Lo PH, Pei D, Sheu WH, Wang SY, Araz M, Bakiner O, Comlekci A, Guler S, Sahin I, Sarac F, Tarkun I, Ukinc K, Yilmaz M, Abdulhakim E, Abraham P, Adamson K, Blagden M, Bundy C, Daly M, Davies M, Deshpande M, Gillings S, Harvey P, Horvathova V, Hristova D, Jaap A, Johnson A, Jones H, Kerrane J, Kilvert A, Ko T, Kumar J, Lindsay R, Litchfield J, McCrimmon R, McKnight J, Millward B, Oyesile B, Purewal T, Ravikumar C, Robinson A, Sathyapalan T, Simpson H, Thomas H, Turner W, Weaver J, Wilding J, Wiles P, Adkins K, Akpunonu B, Albu J, Anagnostis G, Anastasi L, Argoud G, Aroda V, Azizad M, Banerji MA, Bartkowiak A Jr, Bays H, Behn P, Bergenstal R, Bhargava A, Bias D, Bolster E, Buchanan P, Busch R, Chadha C, Chang M, Cheng C, Cohen A, Cohen J, Cole B, Connery L, Cooperman M, Cushman W, DAgostino R, Dayamani P, De Lemos J, De Meireles M, Dean J, DeHart D, Detweiler R, Donovan D, Dugano-Daphnis P, Dulin M, Dunn F, Eaton C, Erickson B, Estevez R, Feinglos M, Fonseca V, Force R, Forker A, Fox D, Gabriel J, Garcia R, Garvey T, Gaudiani L, Getaneh A, Goldberg A, Goldman S, Hairston K, Harris R, Haught W, Hidalgo H Jr, Higgins A, Houchin V, Ison R, Jacobs G, Jaffrani N, Jafry B, Kapsner P, Kaye W, Labroo A, Levinson L, Lewis S, Lillestol M, Luttrell L, Madu I, McNeill R, Merrick B, Metzger F, Nadar V, Nagelberg S, Nash S, Oparil S, Osei K, Papademetriou V, Patel N, Pedley C, Prentiss A, Radbill M, Raisinghani A, Rassouli N, Reddy R, Rees P, Rendell M, Robbins D, Rodbard H, Rohlf J, Roseman H, Rudolph L, Sadler L, Schnall A, Schramm R, Schubart U, Seneviratne T, Shanik M, Snyder H, Sorli C, Stich M, Sweeney ME, Tsao J, Ukwade P, Viswanath D, Vo A, Vogel C, Voyce S, Weintraub H, White J, Wood M, Wu P, Wysham C, Zimmerman R, Pathology/molecular and cellular medicine, Diabetes Pathology & Therapy, and Green JB, Bethel MA, Armstrong PW, Buse JB, Engel SS, Garg J, Josse R, Kaufman KD, Koglin J, Korn S, Lachin JM, McGuire DK, Pencina MJ, Standl E, Stein PP, Suryawanshi S, Van de Werf F, Peterson ED, Holman RR, Holman RR, Peterson ED, Holman RR, Peterson ED, Armstrong PW, Buse JB, Josse RG, Kaufman KD, Koglin J, Korn S, Lachin JM, McGuire DK, Standl E, Stein PP, Suryawanshi S, Van de Werf F, Engel SS, Califf RM, Goldstein BJ, Shapiro DR, Silverman R, Bethel A, Green J, Hayden S, Hannan K, Quintero K, Rorick T, Berdan L, Leloudis D, Califf S, Wilson M, McFarron D, Trollinger K, Pesarchick J, Eskenazi L, Campbell C, Townes O, Tolsma D, Keenan J, Milton J, Athwal R, Darbyshire J, Doran Z, Kennedy I, Gregory V, Garg J, Lokhnygina Y, Prather K, Wolfley A, Usman M, Tajjar A, Gray R, Pfeffer MA, Gerstein HC, Groop L, McMurray JJ, Pocock SJ, Clayton T, Sinay I, Brieger D, Stranks S, Scheen A, Lopes R, Tankova T, Hramiak I, Grado CR, Wenying Y, Ge J, Aschner P, Skrha J, Ambos A, Strandberg T, Travert F, Hanefeld M, Riefflin A, Chan JC, Ofner P, Reddy NK, Christopher J, Mathur A, Arambam P, Mittal S, Manchanda M, Wainstein J, Ambrosio G, Pirags V, Jakuboniene N, Mohamed M, Scott R, White H, Cornel J, Halvorsen S, Tykarski A, Veresiu IA, Dreval AV, Misinkova I, Tai E, Krahulec B, Distiller L, Park Y, Rovira A, Alversson M, Chuang LM, Delibasi T, Adler A, Rodbard HW, Marre M, Goff D, Chacra A, DeVore A, Beaven A, Shah B, Hirsch B, Batch B, Bushnell C, Patel C, Melloni C, Henshaw C, Kong D, McFarron D, Bernecki G, Tillman H, Kang HJ, Green J, Hawes J, Strickler J, Piccini J, Wilder J, Alexander K, Mahaffey K, Patel K, Hyland K, Newby K, Jackson L, Cooper L, Armaganijan L, Szczeh L, Koshizaka M, Roe M, Morse M, Guimaraes P, Hess P, Tricoci P, 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Bostandzhieva R, Cinlikov I, Georgieva M, Iliev D, Ilieva E, Kovacheva S, Liubenova L, Nikitov Z, SHeinikova G, Slavcheva A, Spasova V, Tankova T, Temelkova-Kurktschiev T, Velichka D, Yakov A, Carpentier A, Chiasson JL, Constance C, Dumas R, Filteau P, Garceau C, Hramiak I, Huynh T, Kaiser S, Kornder J, Leiter L, Mereu L, Miller D, Pandey S, Punthakee Z, Rabasa-Lhoret R, Robitaille Y, Saunders K, Sigal R, Sigalas J, Vizel S, Weisnagel S, Woo V, Yale JF, Yared K, Zinman B, Bunster Balocchi LB, Escobar Cerda EE, Garces Flores EE, Lanas Zanetti FT, Larrazabal Miranda Adel P, Morales Alvarado JM, Olivares Cañon CM, Potthoff Cárdenas SH, Raffo Grado CA, Rodriguez Venegas ME, Saavedra Gajardo VA, Westerberg Maldonado BH, Chen LL, Dong J, Guo X, Li QM, Shi B, Tang XL, Yang T, Yang WY, Zheng SX, Aschner Montoya P, Botero Lopez R, Coronel Arroyo JA, Cure CA, Gómez Medina AM, Molina DI, Perez Amador GA, Reyes Rincon A, Urina Triana MA, Valenzuela Rincon A, Vélez Pelaez S, Yupanqui Lozno H, Brabec T, Brychta T, Hasalova Zapletalova J, Havelkova J, Hejnicova K, Hola O, Hornackova M, Hrdina T, Kafkova D, Kellnerova I, Krystl T, Kutejova V, Mikulkova I, Nevrla J, Pantlikova C, Petr M, Racicka E, Sarbochova R, Skrha J, Smolenakova K, Turcinek R, Urbancova K, Vejvodova J, Vondrakova M, Zachoval R, Alt I, Ambos A, Kaasik Ü, Kiiroja K, Lanno R, Märtsin K, Past M, Vides H, Viitas L, Kantola I, Nieminen S, Perhonen M, Strand J, Strandberg T, Valle T, Clergeot A, Couffinhal T, Courreges JP, Gouet D, Moulin P, Travert F, Ziegler O, Badenhoop K, Behnke T, Bender G, Braun M, Dshabrailov J, Hamann A, Hanefeld M, Himpel-Boenninghoff A, Kamke W, Kasperk C, Luedemann J, Mayr P, Merkel M, Oerter EM, Ohlow MA, Ott P, Overhoff U, Paschen B, Remppis R, Riefflin A, Rose L, Schumm-Draeger PM, Segiet T, Strotmann HJ, Stuchlik G, Stürmer W, Thinesse-Mallwitz M, Tytko A, Wendisch U, Wurziger J, Ho AY, Kam G, Kong AP, Lam YY, Lau EY, Lee S, Siu SC, Tomlinson B, Tsang CC, Yeung VT, Dezső E, Dudás M, Földesi I, Fülöp T, Késmárki N, Koranyi L, Nagy K, Ofner P, Oroszlán T, Pécsvárady Z, Ples Z, Taller A, Agarwal P, Ambulkar S, Aravind S, Balaji V, Christopher J, Kalra S, Kesavadev J, Kudalkar H, Kumar A, Misra A, Mithal A, Mohan V, Pitale S, Ramu M, Reddy N, Shah S, Shamanna P, Sharda A, Sharma A, Shunmugavelu M, Srikanta S, Suryaprakash G, Abramov G, Adawi F, Bashkin A, Darawsha M, Fuchs S, Harman-Boehm I, Hayek T, Jaffe A, Knobler H, Minuchin O, Mosseri M, Shechter M, Shimon I, Stern N, Tsur A, Vishlitzky V, Wainstein J, Alfonsi F, Cavalot F, Del Vecchio L, Frisinghelli A, Gambardella S, Lauro D, Lembo G, Leotta S, Mondillo S, Novo S, Pedrinelli R, Piatti P, Salvioni A, Tritto I, Zavaroni DZ, Ahn KJ, Choi KM, Chung C, Han SJ, Kim DM, Kim IJ, Kim MH, Lee IK, Nam M, Park IeB, Park KS, Park TS, Park Y, Rhee EJ, Yoo SJ, Andersone I, Balode A, Eglite R, Gersamija A, Kakurina N, Jegere B, Leitane I, Pastare S, Pirags V, Stalte V, Teterovska D, Baltramonaitiene K, Barsiene L, Ceponis J, Jakuboniene N, Lasiene J, Levinger A, Sirutaviciene A, Sulskiene M, Urbanaviciene L, Valius L, Varanauskiene E, Velickiene D, Mahendran KA, Abu Hassan MR, Aziz NA, Hussein Z, Ismail IS, Kamaruddin NA, Mohamed M, Nordin Z, Nayar SK, Ramanathan GR, Sothiratnam R, Beijerbacht H, Breedveld R, Cornel JH, Den Hartog F, Hermans W, Kietselaer B, Kooy A, Lenderink T, Nierop P, Remmen J, Rojas Lingan G, Ronner E, Van der Heijden R, Van Hessen M, van Kempen W, Voors-Pette C, Westendorp I, Baker J, Benatar J, Cutfield R, Krebs J, Leikis R, Lunt H, Manning P, Scott R, Williams M, Birkeland K, Claudi T, Halvorsen S, Istad H, Karlsson T, Ossum Gronert J, Arciszewska M, Artemiuk E, Blach E, Blicharski T, Cypryk K, Dabrowska M, Górny G, Górska M, Jakubowska I, Jazwinska-Tarnawska E, Karczmarczyk A, Kitowska-Koterla J, Koltowski L, Krzyzagorska E, Pasternak D, Pentela-Nowicka J, Piesiewicz W, Przekwas-Jaruchowska M, Rajzer M, Salamon-Ferenc A, Sawicki A, Skowron T, Śmiałowski A, Tykarski A, Albota A, 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Oral ,medicine.medical_specialty ,Heart diseases ,Glycosylated ,Administration, Oral ,heart failure ,Type 2 diabetes ,Dipeptidyl peptidase-4 inhibitor ,Kaplan-Meier Estimate ,Placebo ,Sitagliptin Phosphate ,Sitagliptin, Cardiovascular Outcomes ,chemistry.chemical_compound ,Drug Therapy ,Double-Blind Method ,Internal medicine ,Diabetes Mellitus ,medicine ,Humans ,Hypoglycemic Agents ,Glycated Hemoglobin ,Hemoglobin A, Glycosylated ,Cardiovascular Diseases ,Diabetes Mellitus, Type 2 ,Drug Therapy, Combination ,Follow-Up Studies ,Heart Diseases ,Heart Failure ,Hospitalization ,Pyrazines ,Triazoles ,Medicine (all) ,business.industry ,Semaglutide ,Hemoglobin A ,General Medicine ,ta3121 ,medicine.disease ,Surgery ,Cardiovascular diseases ,chemistry ,Sitagliptin ,Administration ,Combination ,Glycated hemoglobin ,business ,Type 2 ,Alogliptin ,medicine.drug - Abstract
BACKGROUND: Data are lacking on the long-term effect on cardiovascular events of adding sitagliptin, a dipeptidyl peptidase 4 inhibitor, to usual care in patients with type 2 diabetes and cardiovascular disease. METHODS: In this randomized, double-blind study, we assigned 14,671 patients to add either sitagliptin or placebo to their existing therapy. Open-label use of antihyperglycemic therapy was encouraged as required, aimed at reaching individually appropriate glycemic targets in all patients. To determine whether sitagliptin was noninferior to placebo, we used a relative risk of 1.3 as the marginal upper boundary. The primary cardiovascular outcome was a composite of cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for unstable angina. RESULTS: During a median follow-up of 3.0 years, there was a small difference in glycated hemoglobin levels (least-squares mean difference for sitagliptin vs. placebo, -0.29 percentage points; 95% confidence interval [CI], -0.32 to-0.27). Overall, the primary outcome occurred in 839 patients in the sitagliptin group (11.4%; 4.06 per 100 person-years) and 851 patients in the placebo group (11.6%; 4.17 per 100 person-years). Sitagliptin was noninferior to placebo for the primary composite cardiovascular outcome (hazard ratio, 0.98; 95% CI, 0.88 to 1.09; P
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- 2015
43. Surrogate Measurements of Actinide (n,2n) Cross Sections with NeutronSTARS
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Casperson, R., primary, Burke, J., additional, Hughes, R., additional, Akindele, O., additional, Koglin, J., additional, Wang, B., additional, and Tamashiro, A., additional
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- 2016
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44. Pathogenetic mechanisms of cardiac allograft vasculopathy – impact of nitric oxide
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Koglin, J.
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- 2000
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45. First results from NuSTAR observations of Mkn 421
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Balokovic, M, Ajello, M, Blandford, R. D, Boggs, S. E, Borracci, F, Chiang, J, Christensen, F. E, Craig, W. W, Forster, K, Furniss, A, Fürst, F, Ghisellini, G, Giebels, B, Giommi, P, Grefenstette, B. W, Hailey, C. J, Harrison, F. A, Hayashida, M, Humensky, B, Inoue, Y, Koglin, J. E, Krawczynski, H, Madejski, G. M, Madsen, K. K, Meier, D. L, Nelson, T, Ogle, P, Paneque, D, Perri, M, Puccetti, S, Reynolds, C. S, Sbarrato, T, Stern, D, Tagliaferri, G, Urry, C. M, Wehrle, A. E, and Zhang, W. W
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- 2013
46. Kinetic energy of π− p-atoms in liquid and gaseous hydrogen
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Schottmüller, J., Badertscher, A., Daum, M., Goudsmit, P.F.A., Janousch, M., Kettle, P.-R., Koglin, J., Markushin, V.E., and Zhao, Z.G.
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- 1999
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47. Erratum: Delayed Onset of Nonthermal Melting in Single-Crystal Silicon Pumped with Hard X Rays [Phys. Rev. Lett. 120 , 265701 (2018)]
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Pardini, T., primary, Alameda, J., additional, Aquila, A., additional, Boutet, S., additional, Decker, T., additional, Gleason, A. E., additional, Guillet, S., additional, Hamilton, P., additional, Hayes, M., additional, Hill, R., additional, Koglin, J., additional, Kozioziemski, B., additional, Robinson, J., additional, Sokolowski-Tinten, K., additional, Soufli, R., additional, and Hau-Riege, S. P., additional
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- 2020
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48. Blastulation of a zygote to a hatched blastocyst without any clear cell division: an observational finding in a time-lapse system after in vitro fertilization
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Sandi-Monroy, N.L., primary, Musanovic, S., additional, Zhu, D., additional, Eibner, K., additional, Reeka, N., additional, Koglin, J., additional, Bundschu, K., additional, and Gagsteiger, F., additional
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- 2020
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49. Determining the average prompt-fission-neutron multiplicity for Pu239(n,f) via a Pu240(α,α′f) surrogate reaction
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Wang, B. S., primary, Harke, J. T., additional, Akindele, O. A., additional, Casperson, R. J., additional, Hughes, R. O., additional, Koglin, J. D., additional, Kolos, K., additional, Norman, E. B., additional, Ota, S., additional, and Saastamoinen, A., additional
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- 2019
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50. Herztransplantation — State of the Art Today
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Meiser, B. M., von Scheidt, W., Weis, M., Böhm, D., Kur, F., Koglin, J., Reichenspurner, H., Überfuhr, P., and Reichart, B.
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- 1997
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