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7. Uniform data collection in routine clinical practice in cardiovascular patients for optimal care, quality control and research : The Utrecht Cardiovascular Cohort

Author

Asselbergs, Folkert W, Visseren, Frank Lj, Bots, Michiel L, de Borst, Gert J, Buijsrogge, Marc P, Dieleman, Jan M, van Dinther, Baukje Gf, Doevendans, Pieter A, Hoefer, Imo E, Hollander, Monika, de Jong, Pim A, Koenen, Steven V, Pasterkamp, Gerard, Ruigrok, Ynte M, van der Schouw, Yvonne T, Verhaar, Marianne C, Grobbee, Diederick E, Asselbergs, Folkert W, Visseren, Frank Lj, Bots, Michiel L, de Borst, Gert J, Buijsrogge, Marc P, Dieleman, Jan M, van Dinther, Baukje Gf, Doevendans, Pieter A, Hoefer, Imo E, Hollander, Monika, de Jong, Pim A, Koenen, Steven V, Pasterkamp, Gerard, Ruigrok, Ynte M, van der Schouw, Yvonne T, Verhaar, Marianne C, and Grobbee, Diederick E

Published
2017

8. Lower perinatal mortality in preterm born twins than in singletons: A nationwide study from the Netherlands

Author

Arts-assistenten DV&B, MS Verloskunde, Circulatory Health, Groep Timmers, DV&B-MT-Medisch, Brain, Child Health, Geboortecentrum voorzitterschap, Other research (not in main researchprogram), Vasak, Blanka, Verhagen, Jessica J, Koenen, Steven V., Koster, Maria P H, de Reu, Paul A O M, Franx, Arie, Nijhuis, Jan G, Bonsel, Gouke J., Visser, Gerard H A, Arts-assistenten DV&B, MS Verloskunde, Circulatory Health, Groep Timmers, DV&B-MT-Medisch, Brain, Child Health, Geboortecentrum voorzitterschap, Other research (not in main researchprogram), Vasak, Blanka, Verhagen, Jessica J, Koenen, Steven V., Koster, Maria P H, de Reu, Paul A O M, Franx, Arie, Nijhuis, Jan G, Bonsel, Gouke J., and Visser, Gerard H A

Published
2017

9. Uniform data collection in routine clinical practice in cardiovascular patients for optimal care, quality control and research: The Utrecht Cardiovascular Cohort

Author

Cardiologie, Circulatory Health, Team Medisch, Julius Centrum, Interne Geneeskunde Vasculaire, Cardiovasculaire Epi Team 5, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Zorgeenheid Vaatchirurgie Medisch, CTC, Medische staf Anesthesiologie, Brain, Programma management Cardiovasculair, CDL Staf Research, HAG Hart- Vaatziekten, Researchgr. Systems Radiology, MS Verloskunde, Experimentele Afd. Cardiologie 1, CDL Cluster Onderzoek en Onderwijs, ZL Cerebrovasculaire Ziekten Medisch, Cardiovasculaire Epidemiologie, Nefro Vasculaire Geneeskunde, Regenerative Medicine and Stem Cells, Cardiovasculaire Epi Team 9, Asselbergs, Folkert W, Visseren, Frank Lj, Bots, Michiel L, de Borst, Gert J, Buijsrogge, Marc P, Dieleman, Jan M, van Dinther, Baukje Gf, Doevendans, Pieter A, Hoefer, Imo E, Hollander, Monika, de Jong, Pim A, Koenen, Steven V, Pasterkamp, Gerard, Ruigrok, Ynte M, van der Schouw, Yvonne T, Verhaar, Marianne C, Grobbee, Diederick E, Cardiologie, Circulatory Health, Team Medisch, Julius Centrum, Interne Geneeskunde Vasculaire, Cardiovasculaire Epi Team 5, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Zorgeenheid Vaatchirurgie Medisch, CTC, Medische staf Anesthesiologie, Brain, Programma management Cardiovasculair, CDL Staf Research, HAG Hart- Vaatziekten, Researchgr. Systems Radiology, MS Verloskunde, Experimentele Afd. Cardiologie 1, CDL Cluster Onderzoek en Onderwijs, ZL Cerebrovasculaire Ziekten Medisch, Cardiovasculaire Epidemiologie, Nefro Vasculaire Geneeskunde, Regenerative Medicine and Stem Cells, Cardiovasculaire Epi Team 9, Asselbergs, Folkert W, Visseren, Frank Lj, Bots, Michiel L, de Borst, Gert J, Buijsrogge, Marc P, Dieleman, Jan M, van Dinther, Baukje Gf, Doevendans, Pieter A, Hoefer, Imo E, Hollander, Monika, de Jong, Pim A, Koenen, Steven V, Pasterkamp, Gerard, Ruigrok, Ynte M, van der Schouw, Yvonne T, Verhaar, Marianne C, and Grobbee, Diederick E

Published
2017

10. Six uneventful pregnancy outcomes in an extended vascular Ehlers-Danlos syndrome family

Author

Genetica Klinische Genetica, MS Infectieziekten, Circulatory Health, MS Interne Geneeskunde, Zorgeenheid Vaatchirurgie Medisch, MS Verloskunde, Other research (not in main researchprogram), Medische staf Anesthesiologie, Genetica Sectie Genoomdiagnostiek, MS Radiologie, Genetica, Child Health, Cardiologie, Team Medisch, Baas, Annette F., Spiering, Wilko, Moll, Frans L., Page-Christiaens, Lieve, Beenakkers, Ingrid C M, Dooijes, Dennis, Vonken, Evert Jan P A, van der Smagt, Jasper J., Knoers, Nine V., Koenen, Steven V., van Herwaarden, Joost A., Sieswerda, Gertjan T J, Genetica Klinische Genetica, MS Infectieziekten, Circulatory Health, MS Interne Geneeskunde, Zorgeenheid Vaatchirurgie Medisch, MS Verloskunde, Other research (not in main researchprogram), Medische staf Anesthesiologie, Genetica Sectie Genoomdiagnostiek, MS Radiologie, Genetica, Child Health, Cardiologie, Team Medisch, Baas, Annette F., Spiering, Wilko, Moll, Frans L., Page-Christiaens, Lieve, Beenakkers, Ingrid C M, Dooijes, Dennis, Vonken, Evert Jan P A, van der Smagt, Jasper J., Knoers, Nine V., Koenen, Steven V., van Herwaarden, Joost A., and Sieswerda, Gertjan T J

Published
2017

11. Uniform data collection in routine clinical practice in cardiovascular patients for optimal care, quality control and research: The Utrecht Cardiovascular Cohort

Author

Asselbergs, Folkert W, primary, Visseren, Frank LJ, additional, Bots, Michiel L, additional, de Borst, Gert J, additional, Buijsrogge, Marc P, additional, Dieleman, Jan M, additional, van Dinther, Baukje GF, additional, Doevendans, Pieter A, additional, Hoefer, Imo E, additional, Hollander, Monika, additional, de Jong, Pim A, additional, Koenen, Steven V, additional, Pasterkamp, Gerard, additional, Ruigrok, Ynte M, additional, van der Schouw, Yvonne T, additional, Verhaar, Marianne C, additional, and Grobbee, Diederick E, additional

Published
2017
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12. Terminating pregnancy for severe hypertension when the fetus is considered non-viable : a retrospective cohort study

Author

Van Eerden, Leonoor, Van Oostwaard, Miriam F., Zeeman, Gerda G., Page-Christiaens, Godelieve C M, Pajkrt, Eva, Duvekot, Johannes J., Vandenbussche, Frank P., Oei, Swan G., Scheepers, Hubertina C J, Van Eyck, Jim, Middeldorp, Johanna M., Koenen, Steven V., De Groot, Christianne J M, Bolte, Antoinette C., Van Eerden, Leonoor, Van Oostwaard, Miriam F., Zeeman, Gerda G., Page-Christiaens, Godelieve C M, Pajkrt, Eva, Duvekot, Johannes J., Vandenbussche, Frank P., Oei, Swan G., Scheepers, Hubertina C J, Van Eyck, Jim, Middeldorp, Johanna M., Koenen, Steven V., De Groot, Christianne J M, and Bolte, Antoinette C.

Published
2016

14. Spiral artery remodeling and maternal cardiovascular risk: the spiral artery remodeling (SPAR) study

Author

Circulatory Health, MS Verloskunde, Metabole ziekten patientenzorg, Pathologie Pathologen staf, Cancer, Brain, DV&B-MT-Medisch, Veerbeek, Jan H W, Brouwers, Laura, Koster, Maria P H, Koenen, Steven V., van Vliet, Elvira O G, Nikkels, Peter G J, Franx, Arie, van Rijn, Bas B., Circulatory Health, MS Verloskunde, Metabole ziekten patientenzorg, Pathologie Pathologen staf, Cancer, Brain, DV&B-MT-Medisch, Veerbeek, Jan H W, Brouwers, Laura, Koster, Maria P H, Koenen, Steven V., van Vliet, Elvira O G, Nikkels, Peter G J, Franx, Arie, and van Rijn, Bas B.

Published
2016

15. Terminating pregnancy for severe hypertension when the fetus is considered non-viable: a retrospective cohort study

Author

UMC Utrecht, MS Verloskunde, Other research (not in main researchprogram), Circulatory Health, Van Eerden, Leonoor, Van Oostwaard, Miriam F., Zeeman, Gerda G., Page-Christiaens, Godelieve C M, Pajkrt, Eva, Duvekot, Johannes J., Vandenbussche, Frank P., Oei, Swan G., Scheepers, Hubertina C J, Van Eyck, Jim, Middeldorp, Johanna M., Koenen, Steven V., De Groot, Christianne J M, Bolte, Antoinette C., UMC Utrecht, MS Verloskunde, Other research (not in main researchprogram), Circulatory Health, Van Eerden, Leonoor, Van Oostwaard, Miriam F., Zeeman, Gerda G., Page-Christiaens, Godelieve C M, Pajkrt, Eva, Duvekot, Johannes J., Vandenbussche, Frank P., Oei, Swan G., Scheepers, Hubertina C J, Van Eyck, Jim, Middeldorp, Johanna M., Koenen, Steven V., De Groot, Christianne J M, and Bolte, Antoinette C.

Published
2016

16. Effect of in vivo fetal infusion of dexamethasone at 0.75 GA on fetal ovine resistance artery responses to ET-1

Author

DOCHERTY, CHERYL C., KALMAR-NAGY, JUDIT, ENGELEN, MARC, KOENEN, STEVEN V., NIJLAND, MARK, KUC, RHODA E., DAVENPORT, ANTHONY P., and NATHANIELSZ, PETER W.

Subjects
Physiology -- Research, Corticosteroids -- Physiological aspects, Blood pressure -- Physiological aspects, Dexamethasone -- Physiological aspects, Biological sciences
Abstract

Effect of in vivo fetal infusion of dexamethasone at 0.75 GA on fetal ovine resistance artery responses to ET-1. Am J Physiol Regulatory Integrative Comp Physiol 281: R261-R268, 2001.--At 110-111 days gestation, instrumented fetal sheep were administered saline or dexamethasone (2.2 [micro]g [multiplied by] [kg.sup.-1]. [h.sup.-1] iv) for 48 h. Measurement of fetal blood pressure showed a greater increase in dexamethasone-treated (n = 6) compared with control (n = 5) fetuses (7.3 [+ or -] 2.3 vs. 0.6 [+ or -] 2.3 mmHg, P [is less than] 0.05). Fetuses were delivered by cesarean section, and the femoral muscle and brain were obtained under halothane anesthesia. Femoral and middle cerebral arteries (~320-[micro]m internal diameter) were evaluated using wire myography. Sensitivity to KCl (2.5-125 mM) and the magnitude of the maximal vasoconstriction to 125 mM [K.sup.+] were similar in femoral and middle cerebral arteries from dexamethasone-treated vs. control fetuses. Acetylcholine-induced vasorelaxation was similar in femoral arteries from control and dexamethasone-treated fetuses. Middle cerebral arteries did not relax to acetylcholine. Sensitivity to endothelin-1 (ET-1; 0.1 pM-0.1 [micro]M) and magnitude of the ET-1-induced vasoconstriction were greater in femoral arteries from dexamethasone-treated vs. control fetuses (P [is less than] 0.05). Autoradiographical studies with receptor-specific ligands demonstrated increased [ET.sub.A]-receptor binding, the principal receptor subtype, in femoral muscle vessels (P [is less than] 0.001) but decreased [ET.sub.A]-receptor binding in middle cerebral arteries (P [is less than] 0.01) from dexamethasone-treated compared with control fetuses. Relatively little [ET.sub.B]-receptor binding was evident in all tissues examined. We conclude that hyperreactivity to ET-1, due to increased [ET.sub.A]-receptor binding, may be involved in the dexamethasone-induced increase in peripheral vascular resistance in fetal sheep in vivo. glucocorticoids; blood pressure; fetal sheep

Published
2001

17. Six uneventful pregnancy outcomes in an extended vascular Ehlers-Danlos syndrome family

Author

Baas, Annette F., primary, Spiering, Wilko, additional, Moll, Frans L., additional, Page-Christiaens, Lieve, additional, Beenakkers, Ingrid C. M., additional, Dooijes, Dennis, additional, Vonken, Evert-Jan P. A., additional, van der Smagt, Jasper J., additional, Knoers, Nine V., additional, Koenen, Steven V., additional, van Herwaarden, Joost A., additional, and Sieswerda, Gertjan Tj., additional

Published
2016
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18. Terminating pregnancy for severe hypertension when the fetus is considered non-viable: a retrospective cohort study

Author

Van Eerden, Leonoor, primary, Van Oostwaard, Miriam F., additional, Zeeman, Gerda G., additional, Page-Christiaens, Godelieve C.M., additional, Pajkrt, Eva, additional, Duvekot, Johannes J., additional, Vandenbussche, Frank P., additional, Oei, Swan G., additional, Scheepers, Hubertina C.J., additional, Van Eyck, Jim, additional, Middeldorp, Johanna M., additional, Koenen, Steven V., additional, De Groot, Christianne J.M., additional, and Bolte, Antoinette C., additional

Published
2016
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20. Cardiovascular Disease Risk Factors After Early-Onset Preeclampsia, Late-Onset Preeclampsia, and Pregnancy-Induced Hypertension

Author

Veerbeek, Jan H. W., Hermes, Wietske, Breimer, Anath Y., van Rijn, Bas B., Koenen, Steven V., Mol, Ben W., Franx, Arie, de Groot, Christianne J. M., Koster, Maria P. H., Koster, M.P.H. (Wendy), Veerbeek, Jan H. W., Hermes, Wietske, Breimer, Anath Y., van Rijn, Bas B., Koenen, Steven V., Mol, Ben W., Franx, Arie, de Groot, Christianne J. M., Koster, Maria P. H., and Koster, M.P.H. (Wendy)

Published
2015

21. Evaluation of strategies regarding management of imminent preterm delivery before 32 weeks of gestation: a regional cohort study among 1375 women in the Netherlands

Author

Other research (not in main researchprogram), MS Verloskunde, Circulatory Health, MS Neonatologie, Brain, Boesveld, Merel, Oudijk, Martijn A., Koenen, Steven V., Brouwers, Hens A, Van Beek, Erik, Boon, Janine, Drogtrop, Addy, Euser, Robert, Evers, Inge M., Fiedeldeij, Cora A., Heida, Karst Y., Huisjes, Anjoke J M, Muijsers, Guido J J M, Schierbeek, Jaap M., Kwee, Anneke, Other research (not in main researchprogram), MS Verloskunde, Circulatory Health, MS Neonatologie, Brain, Boesveld, Merel, Oudijk, Martijn A., Koenen, Steven V., Brouwers, Hens A, Van Beek, Erik, Boon, Janine, Drogtrop, Addy, Euser, Robert, Evers, Inge M., Fiedeldeij, Cora A., Heida, Karst Y., Huisjes, Anjoke J M, Muijsers, Guido J J M, Schierbeek, Jaap M., and Kwee, Anneke

Published
2015

22. Cardiovascular Disease Risk Factors After Early-Onset Preeclampsia, Late-Onset Preeclampsia, and Pregnancy-Induced Hypertension

Author

MS Verloskunde, Cancer, Child Health, Circulatory Health, Groep Timmers, Veerbeek, Jan H. W., Hermes, Wietske, Breimer, Anath Y., van Rijn, Bas B., Koenen, Steven V., Mol, Ben W., Franx, Arie, de Groot, Christianne J. M., Koster, Maria P. H., Koster, M.P.H. (Wendy), MS Verloskunde, Cancer, Child Health, Circulatory Health, Groep Timmers, Veerbeek, Jan H. W., Hermes, Wietske, Breimer, Anath Y., van Rijn, Bas B., Koenen, Steven V., Mol, Ben W., Franx, Arie, de Groot, Christianne J. M., Koster, Maria P. H., and Koster, M.P.H. (Wendy)

Published
2015

23. O66. Comparison of immediate delivery versus expectant management in women with severe early onset preeclampsia before 26 weeks of gestation

Author

Van Oostwaard, Miriam F., primary, Van Eerden, Leonoor, additional, De Laat, Monique W., additional, Duvekot, Hans J., additional, Erwich, Jan Jaap H.M., additional, Bloemenkamp, Kitty W.M., additional, Bolte, Antoinette, additional, Bosma, Joost P.F., additional, Koenen, Steven V., additional, Kornelisse, René F., additional, Rethans, Bente, additional, Van Runnard Heimel, Pieter, additional, Scheepers, Hubertina C.J., additional, Ganzevoort, Wessel, additional, Mol, Ben Willem J., additional, De Groot, Christianne J., additional, and Gaugler-Senden, Ingrid P.M., additional

Published
2015
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32. Evaluation of antenatal corticosteroid prescribing patterns among 984 women at risk for preterm delivery.

Author

Boesveld, Merel, Heida, Karst Y., Oudijk, Martijn A., Brouwers, Hens A. A., Koenen, Steven V., and Kwee, Anneke

Subjects
LABOR complications (Obstetrics), HIGH-risk pregnancy, DURATION of pregnancy, CORTICOSTEROIDS, UTERINE hemorrhage
Abstract

Objective: To evaluate the prescribing patterns of the first antenatal corticosteroids (ACS) course in our tertiary referral centre from 2005 until 2010. Study design: We conducted a retrospective cohort study including all women who received ACS between 24+0 and 34+0 weeks of gestation. Main outcome measure was the number of women who delivered within 7 d after ACS administration. The time interval from administration to delivery was compared between women with different indications. Furthermore, all women delivering between 24+0 and 34+0 weeks of gestation who did not receive ACS were identified. Results: 1008 women received ACS, 15 (1.5%) women were lost to follow up. Main indications were suspected preterm labour, preterm prelabour rupture of membranes, maternal indication, foetal indication and vaginal blood loss (VBL). Overall, 447 (45.4%) women delivered ≤7 d after ACS administration. This percentage was 13.6% in women with VBL and 61.5% in women with maternal indication. During the study period, 1267 women delivered before 34 weeks of gestation, 126 (9.9%) women did not receive ACS. Conclusions: The time interval from ACS administration to delivery differs per indication. Women with VBL are most often over treated. The timing of the first ACS course should be improved. [ABSTRACT FROM AUTHOR]

Published
2014
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34. C-reactive protein and fibrinogen levels as determinants of recurrent preeclampsia

Author

Rijn, Bas B. van, Veerbeek, Jan H., Scholtens, Lenneke C., Uiterweer, Emiel D. Post, Koster, Maria P., Peeters, Louis L., Koenen, Steven V., Bruinse, Hein W., and Franx, Arie

Abstract

Women with a history of early-onset preeclampsia have an increased risk of recurrent preeclampsia and are more prone to develop future cardiovascular disease. At present, risk factors underlying this association are not well characterized. We investigated whether the risk of recurrent preeclampsia is associated with pre-pregnancy levels of common cardiovascular and inflammatory markers.

Published
2014
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35. Terminating pregnancy for severe hypertension when the fetus is considered non-viable: a retrospective cohort study.

Author

Van Eerden L, Van Oostwaard MF, Zeeman GG, Page-Christiaens GC, Pajkrt E, Duvekot JJ, Vandenbussche FP, Oei SG, Scheepers HC, Van Eyck J, Middeldorp JM, Koenen SV, De Groot CJ, and Bolte AC

Subjects
Adult, Eclampsia diagnosis, Female, Gestational Age, HELLP Syndrome diagnosis, Humans, Netherlands, Pre-Eclampsia diagnosis, Pregnancy, Retrospective Studies, Abortion, Induced statistics & numerical data, Eclampsia therapy, HELLP Syndrome therapy, Pre-Eclampsia therapy
Abstract

Objective: To investigate frequency and practise of termination of pregnancy for early-onset hypertensive disorders where the fetus is considered to be non-viable., Study Design: Retrospective cohort study in all Dutch tertiary perinatal care centres (n=10), between January 2000 and January 2014. All women who underwent termination of pregnancy, without fetal surveillance or intention to intervene for fetal reasons, for early-onset hypertensive disorders in pregnancy, were analyzed. Women eligible for this study were identified in the local delivery databases. Medical records were used to collect relevant data., Results: Between January 2000 and January 2014, 2,456,584 women delivered in The Netherlands, of which 238,448 (9.7%) in a tertiary care centre. A total of 161 pregnancy terminations (11-12 per year) for severe early-onset preeclampsia were identified, including 6 women with a twin pregnancy. Mean gestational age at termination was 172 days (GA 24 4/7 )±9.4 days. In 70% of cases termination was performed at or shortly after 24 weeks' gestation. 74.5% of women developed HELLP syndrome (n=96), eclampsia (n=10) or needed admission to an ICU (n=14). Birth weight was below 500g in 64% of cases. In 69% of the cases the estimated fetal weight was within a 10% margin of the actual birth weight., Conclusion: Termination of pregnancy for early-onset hypertensive disorders without intervention for fetal indication occurs approximately 12 times per year in The Netherlands. More data are needed to investigate contemporary best practice regarding termination of pregnancy for early-onset hypertensive indications at the limits of fetal viability. Considering the frequency of maternal complications, termination of pregnancy and not expectant management should be considered for all women presenting with severe early onset hypertensive disorders at the limits of fetal viability., (Copyright © 2016 The Author(s). Published by Elsevier Ireland Ltd.. All rights reserved.)

Published
2016
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