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Your search keyword '"Kochhan, Katharina"' showing total 4 results
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4 results on '"Kochhan, Katharina"'

1. Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase

Author

Merle, Nastasja, Elmshäuser, Sabrina, Strassheimer, Florian, Wanzel, Michael, König, Alexander M., Funk, Julianne, Neumann, Michelle, Kochhan, Katharina, Helmprobst, Frederik, Pagenstecher, Axel, Nist, Andrea, Mernberger, Marco, Schneider, André, Braun, Thomas, Borggrefe, Tilman, Savai, Rajkumar, Timofeev, Oleg, and Stiewe, Thorsten

Published
2022
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2. Functional diversity of theTP53mutome revealed by saturating CRISPR mutagenesis

Author

Funk, Julianne, primary, Klimovich, Maria, additional, Pavlakis, Evangelos, additional, Neumann, Michelle, additional, Drangenstein, Daniel, additional, Noeparast, Maxim, additional, Hunold, Pascal, additional, Borowek, Anna, additional, Balourdas, Dimitrios-Ilias, additional, Kochhan, Katharina, additional, Merle, Nastasja, additional, Bullwinkel, Imke, additional, Wanzel, Michael, additional, Elmshäuser, Sabrina, additional, Nist, Andrea, additional, Procida, Tara, additional, Bartkuhn, Marek, additional, Humpert, Katharina, additional, Mernberger, Marco, additional, Savai, Rajkumar, additional, Joerger, Andreas C., additional, and Stiewe, Thorsten, additional

Published
2023
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3. Additional file 1 of Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase

Author

Merle, Nastasja, Elmshäuser, Sabrina, Strassheimer, Florian, Wanzel, Michael, König, Alexander M., Funk, Julianne, Neumann, Michelle, Kochhan, Katharina, Helmprobst, Frederik, Pagenstecher, Axel, Nist, Andrea, Mernberger, Marco, Schneider, André, Braun, Thomas, Borggrefe, Tilman, Savai, Rajkumar, Timofeev, Oleg, and Stiewe, Thorsten

Abstract

Additional file 1: Survival of non-GLuc transgenic SCLC mice. LSL-Cas9 mice (without GLuc transgene) were intratracheally infected with either AV-C.Cre, AV-PR.Cre or AV-PRL.Cre as depicted in Fig. 6a. Shown is the Kaplan-Meier survival plot with group size, median survival and P-values from Log-rank (Mantel-Cox) test

Published
2022
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4. Additional file 2 of Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase

Author

Merle, Nastasja, Elmshäuser, Sabrina, Strassheimer, Florian, Wanzel, Michael, König, Alexander M., Funk, Julianne, Neumann, Michelle, Kochhan, Katharina, Helmprobst, Frederik, Pagenstecher, Axel, Nist, Andrea, Mernberger, Marco, Schneider, André, Braun, Thomas, Borggrefe, Tilman, Savai, Rajkumar, Timofeev, Oleg, and Stiewe, Thorsten

Abstract

Additional file 2: Mutation spectra of SCLC cell lines. Cell lines were established from AV-PR.Cre (n=3) and AV-PRL.Cre (n=5) SCLC tumors and analyzed by deep sequencing of the sgRNA target regions in Trp53, Rb1 and Rbl2. Depicted is the frequency of wild-type and mutant reads. For mutant reads, the Top5 mutations are color-coded as deletions or insertions and labelled with the number of deleted, inserted or substituted base pairs. Less frequent mutations are summarized as ‘others’.

Published
2022
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