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Postoperative atrial fibrillation (POAF) after cardiac surgery is associated with higher morbidity and mortality. The presence of an aberrant p-terminal force vector in lead V1 (PTFV1) has been identified as a significant predictor of atrial fibrillation in the non-surgical population. It is uncertain whether an association exists between PTFV1 and new-onset POAF in patients after cardiac surgery. In this secondary analysis, adult patients undergoing on-pump cardiac surgery for aortocoronary bypasses, valve surgery, combined bypass, and valve surgery were analyzed from 12/2018 to 08/2020. Patients who had a previous occurrence of atrial fibrillation or atrial flutter, patients with pacemakers and/or implantable cardioverter-defibrillators (ICDs), and those who did not have an electrocardiogram (ECG) performed within the 3 months before surgery were excluded. In addition, ECGs that were considered to be of low quality were also removed. Preoperative 12-lead ECGs were examined and the PTFV1 measured. Secondarily, we examined the P-wave length in lead II, the area under the P-wave in lead II, PR-interval, and QRS duration in lead V1 and II. The occurrence of POAF was extracted from the hospital record. Out of a total of 252 patients, 62 patients (24.6%) developed new onset POAF during their hospital stay. POAF occurred primarily in older patients, those with poor renal function, and those with a larger left atrium. Analysis of (odds ratios) ORs revealed that age, creatinine clearance, valve surgery, and left atrial volume index (LAVI) were associated with POAF. In the multivariable analysis, only age presented a significant correlation with postoperative atrial fibrillation (POAF). There was no observed relationship between any of the parameters based on ECG and the occurrence of POAF. No association was found between PTFV1 or other ECG based measurements and new onset POAF in cardiac surgery patients. Age was the only independent predictor of POAF. [ABSTRACT FROM AUTHOR]