1. Growth rate of pulmonary metastases in human sarcomas.
- Author
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Band PR and Kocandrle C
- Subjects
- Adolescent, Adult, Aged, Bone Neoplasms drug therapy, Child, Female, Fibrosarcoma drug therapy, Hemangiopericytoma drug therapy, Humans, Leiomyosarcoma drug therapy, Liposarcoma drug therapy, Lomustine therapeutic use, Male, Middle Aged, Neoplasm Metastasis, Osteosarcoma drug therapy, Sarcoma, Ewing drug therapy, Time Factors, Lung Neoplasms drug therapy, Sarcoma drug therapy
- Abstract
The growth rate of spherical pulmonary metastases was studied in 15 patients with osseous and soft tissue sarcoma. The median volume doubling time (Dt) was 25 days. The time from diagnosis of the primary tumor to occurrence of pulmonary metastases correlated directly with the length of Dt. No correlation between Dt and tumor histology was observed. The effect of therapy on the tumor growth curve was studied in 1 patient. The therapeutic implications derived from the quantitative evaluation of tumor growth rate are discussed.
- Published
- 1975
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