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Copyright of Turkish Journal of Clinical & Cardiovascular Perfusion / Türk Klinik ve Kardiyovasküler Perfüzyon Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkish Journal of Clinical & Cardiovascular Perfusion / Türk Klinik ve Kardiyovasküler Perfüzyon Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Turkish Journal of Clinical & Cardiovascular Perfusion / Türk Klinik ve Kardiyovasküler Perfüzyon Dergisi is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Coronary artery anomalies are being more frequently diagnosed these days both because increasing numbers of patients are undergoing diagnostic studies and because advanced radiographic imaging methods are now commonly available. An isolated single coronary artery giving rise to the main coronary branches is a rare congenital anomaly. In this report we present a patient with a solitary coronary ostium, with both the left and right coronary artery systems arising from it, and then following their usual courses. This case was diagnosed incidentally during conventional angiography.

The effect of pulmonary embolism (PE) on prostacyclin (PGI2) and thromboxane A2 (TxA2) levels and PGI2- TxA2 ratio (PTR) was investigated in a series of canine experiments. Group I dogs (n = 8) underwent experimental PE with autologous clot. Group II dogs (n=8) received imidazole (30 mg/kg), five minutes before PE to inhibit thromboxane synthesis and to simulate antiplatelet drug therapy. Group III dogs (n=8) received only imidazole without PE. In Groups I and II, PGI2 levels (measured as the 6-keto PGF1α metabolite) increased significantly after PE (p < 0.05), whereas they were not altered in Group III. PE caused a sharper increase in TxA2 levels (measured as the thromboxane B 2 metabolite) in Group I (p < 0.001). Imidazole decreased TxA 2 levels both in Groups II and III (p < 0.05). The reference values (ie, before PE and before imidazole) of PTR were not significantly different among the three groups: 3.8±0.4 in Group I, 3.6±0.2 in Group II, and 3.8 ±0.1 in Group III (mean 3.7±0.2). In Group I, PE resulted in a decrease in the PTR (p < 0.05), which reached its peak significance at ten minutes (from 3.8±0.4 to 1.8±0.2). Imidazole-treated groups showed a significant increase in the PTR irrespective of PE (p < 0.05) by virtue of the decreased thromboxane B2 values. It is concluded that, a PTR ratio of 2 or less is suggestive of PE in patients who do not receive antiplatelet therapy. [ABSTRACT FROM PUBLISHER]