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39 results on '"Kocabas, Ali"'

1. Prevalence of chronic cough, its risk factors and population attributable risk in the Burden of Obstructive Lung Disease (BOLD) study: a multinational cross-sectional study

Author

Hafizi, Hasan, Aliko, Anila, Bardhi, Donika, Tafa, Holta, Thanasi, Natasha, Mezini, Arian, Teferici, Alma, Todri, Dafina, Nikolla, Jolanda, Kazasi, Rezarta, Cherkaski, Hamid Hacene, Bengrait, Amira, Haddad, Tabarek, Zgaoula, Ibtissem, Ghit, Maamar, Roubhia, Abdelhamid, Boudra, Soumaya, Atoui, Feryal, Yakoubi, Randa, Benali, Rachid, Bencheikh, Abdelghani, Ait-Khaled, Nadia, Jenkins, Christine, Marks, Guy, Bird, Tessa, Espinel, Paola, Hardaker, Kate, Toelle, Brett, Studnicka, Michael, Dawes, Torkil, Lamprecht, Bernd, Schirhofer, Lea, Islam, Akramul, Ahmed, Syed Masud, Islam, Shayla, Islam, Qazi Shafayetul, Mesbah-Ul-Haque, Chowdhury, Tridib Roy, Chatterjee, Sukantha Kumar, Mia, Dulal, Chandra Das, Shyamal, Rahman, Mizanur, Islam, Nazrul, Uddin, Shahaz, Islam, Nurul, Khatun, Luiza, Parvin, Monira, Khan, Abdul Awal, Islam, Maidul, Lawin, Herve, Kpangon, Arsene, Kpossou, Karl, Agodokpessi, Gildas, Ayelo, Paul, Fayomi, Benjamin, Mbatchou, Bertrand, Ashu, Atongno Humphrey, Tan, Wan C., Wang, Wen, Zhong, NanShan, Liu, Shengming, Lu, Jiachun, Ran, Pixin, Wang, Dali, Zheng, Jin-ping, Zhou, Yumin, Jogi, Rain, Laja, Hendrik, Ulst, Katrin, Zobel, Vappu, Lill, Toomas-Julius, Adegnika, Ayola Akim, Welte, Tobias, Bodemann, Isabelle, Geldmacher, Henning, SchwedaLinow, Alexandra, Gislason, Thorarinn, Benedikdtsdottir, Bryndis, Jorundsdottir, Kristin, Lovisa Gudmundsdottir, Gudmundsdottir, Sigrun, Gudmundsson, Gunnar, Rao, Mahesh, Koul, Parvaiz A., Malik, Sajjad, Hakim, Nissar A., Khan, Umar Hafiz, Chowgule, Rohini, Shetye, Vasant, Raphael, Jonelle, Almeda, Rosel, Tawde, Mahesh, Tadvi, Rafiq, Katkar, Sunil, Kadam, Milind, Dhanawade, Rupesh, Ghurup, Umesh, Juvekar, Sanjay, Hirve, Siddhi, Sambhudas, Somnath, Chaidhary, Bharat, Tambe, Meera, Pingale, Savita, Umap, Arati, Umap, Archana, Shelar, Nitin, Devchakke, Sampada, Chaudhary, Sharda, Bondre, Suvarna, Walke, Savita, Gawhane, Ashleshsa, Sapkal, Anil, Argade, Rupali, Gaikwad, Vijay, Salvi, Sundeep, Brashier, Bill, Londhe, Jyoti, Madas, Sapna, Aquart-Stewart, Althea, Aikman, Akosua Francia, Sooronbaev, Talant M., Estebesova, Bermet M., Akmatalieva, Meerim, Usenbaeva, Saadat, Kydyrova, Jypara, Bostonova, Eliza, Sheraliev, Ulan, Marajapov, Nuridin, Toktogulova, Nurgul, Emilov, Berik, Azilova, Toktogul, Beishekeeva, Gulnara, Dononbaeva, Nasyikat, Tabyshova, Aijamal, Mortimer, Kevin, Nyapigoti, Wezzie, Mwangoka, Ernest, Kambwili, Mayamiko, Chipeta, Martha, Banda, Gloria, Mkandawire, Suzgo, Banda, Justice, Loh, Li-Cher, Rashid, Abdul, Sholehah, Siti, Benjelloun, Mohamed C., Nejjari, Chakib, Elbiaze, Mohamed, El Rhazi, Karima, Wouters, E.F.M., Wesseling, G.J., Obaseki, Daniel, Erhabor, Gregory, Awopeju, Olayemi, Adewole, Olufemi, Gulsvik, Amund, Endresen, Tina, Svendsen, Lene, Nafees, Asaad A., Irfan, Muhammad, Fatmi, Zafar, Zahidie, Aysha, Shaukat, Natasha, Iqbal, Meesha, Idolor, Luisito F., de Guia, Teresita S., Francisco, Norberto A., Roa, Camilo C., Ayuyao, Fernando G., Tady, Cecil Z., Tan, Daniel T., Banal-Yang, Sylvia, Balanag, Vincent M., Jr., Reyes, Maria Teresita N., Dantes, Renato B., Amarillo, Lourdes, Berratio, Lakan U., Fernandez, Lenora C., Garcia, Gerard S., Naval, Sullian S., Reyes, Thessa, Roa, Camilo C., Jr., Sanchez, Flordeliza, Simpao, Leander P., Nizankowska-Mogilnicka, Ewa, Frey, Jakub, Harat, Rafal, Mejza, Filip, Nastalek, Pawel, Pajak, Andrzej, Skucha, Wojciech, Szczeklik, Andrzej, Twardowska, Magda, Barbara, Cristina, Rodrigues, Fatima, Dias, Herminia, Cardoso, Joao, Almeida, João, Matos, Maria Joao, Simão, Paula, Santos, Moutinho, Ferreira, Reis, Al Ghobain, M., Alorainy, H., El-Hamad, E., Al Hajjaj, M., Hashi, A., Dela, R., Fanuncio, R., Doloriel, E., Marciano, I., Safia, L., Bateman, Eric, Jithoo, Anamika, Adams, Desiree, Barnes, Edward, Freeman, Jasper, Hayes, Anton, Hlengwa, Sipho, Johannisen, Christine, Koopman, Mariana, Louw, Innocentia, Ludick, Ina, Olckers, Alta, Ryck, Johanna, Storbeck, Janita, Gunasekera, Kirthi, Wickremasinghe, Rajitha, Elsony, Asma, Elsadig, Hana A., Osman, Nada Bakery, Noory, Bandar Salah, Mohamed, Monjda Awad, Akasha Ahmed Osman, Hasab Alrasoul, Moham ed Elhassan, Namarig, El Zain, Abdel Mu’is, Mohamaden, Marwa Mohamed, Khalifa, Suhaiba, Elhadi, Mahmoud, Hassan, Mohand, Abdelmonam, Dalia, Janson, Christer, Olafsdottir, Inga Sif, Nisser, Katarina, SpetzNystrom, Ulrike, Hagg, Gunilla, Lund, GunMarie, Seemungal, Terence, Lutchmansingh, Fallon, Conyette, Liane, Harrabi, Imed, Denguezli, Myriam, Tabka, Zouhair, Daldoul, Hager, Boukheroufa, Zaki, Chouikha, Firas, Khalifa, Wahbi Belhaj, Kocabas, Ali, Hancioglu, Attila, Hanta, Ismail, Kuleci, Sedat, Turkyilmaz, Ahmet Sinan, Umut, Sema, Unalan, Turgay, Burney, Peter G.J., Gnatiuc, Louisa, Azar, Hadia, Patel, Jaymini, Amor, Caron, Potts, James, Tumilty, Michael, McLean, Fiona, Dudhaiya, Risha, Buist, A. Sonia, McBurnie, Mary Ann, Vollmer, William M., Gillespie, Suzanne, Sullivan, Sean, Lee, Todd A., Weiss, Kevin B., Jensen, Robert L., Crapo, Robert, Enright, Paul, Mannino, David M., Cain, John, Copeland, Rebecca, Hazen, Dana, Methvin, Jennifer, Abozid, Hazim, Burney, Peter, Hartl, Sylvia, Breyer-Kohansal, Robab, Al Ghobain, Mohammed, Denguezli, Meriam, Loh, Li Cher, Paraguas, Stefanni Nonna, Franssen, Frits M.E., Mannino, David, Anand, Mahesh Padukudru, Buist, Sonia, El Sony, Asma, Breyer, Marie-Kathrin, Burghuber, Otto C., Wouters, Emiel F.M., and Amaral, Andre F.S.

Published
2024
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2. Overdiagnosis of COPD in Subjects With Unobstructed Spirometry: A BOLD Analysis

Author

Zhong, NanShan, Liu, Shengming, Lu, Jiachun, Ran, Pixin, Wang, Dali, Zheng, Jingping, Zhou, Yumin, Kocabaş, Ali, Hancioglu, Attila, Hanta, Ismail, Kuleci, Sedat, Turkyilmaz, Ahmet Sinan, Umut, Sema, Unalan, Turgay, Studnicka, Michael, Dawes, Torkil, Lamprecht, Bernd, Sator, Lea, Bateman, Eric, Jithoo, Anamika, Adams, Desiree, Barnes, Edward, Freeman, Jasper, Hayes, Anton, Hlengwa, Sipho, Johannisen, Christine, Koopman, Mariana, Louw, Innocentia, Ludick, Ina, Olckers, Alta, Ryck, Johanna, Storbeck, Janita, Gislason, Thorarinn, Benedikdtsdottir, Bryndis, Jörundsdottir, Kristin, Gudmundsdottir, Lovisa, Gudmundsdottir, Sigrun, Gundmundsson, Gunnar, Nizankowska-Mogilnicka, Ewa, Frey, Jakub, Harat, Rafal, Mejza, Filip, Nastalek, Pawel, Pajak, Andrzej, Skucha, Wojciech, Szczeklik, Andrzej, Twardowska, Magda, Welte, Tobias, Bodemann, Isabelle, Geldmacher, Henning, Schweda-Linow, Alexandra, Gulsvik, Amund, Endresen, Tina, Svendsen, Lene, Tan, Wan C., Wang, Wen, Mannino, David M., Cain, John, Copeland, Rebecca, Hazen, Dana, Methvin, Jennifer, Dantes, Renato B., Amarillo, Lourdes, Berratio, Lakan U., Fernandez, Lenora C., Francisco, Norberto A., Garcia, Gerard S., de Guia, Teresita S., Idolor, Luisito F., Naval, Sullian S., Reyes, Thessa, Roa, Camilo C., Jr., Sanchez, Ma. Flordeliza, Simpao, Leander P., Jenkins, Christine, Marks, Guy, Bird, Tessa, Espinel, Paola, Hardaker, Kate, Toelle, Brett, Burney, Peter G.J., Amor, Caron, Potts, James, Tumilty, Michael, McLean, Fiona, Wouters, E.F.M., Wesseling, G.J., Bárbara, Cristina, Rodrigues, Fátima, Dias, Hermínia, Cardoso, João, Almeida, João, Matos, Maria João, Simão, Paula, Santos, Moutinho, Ferreira, Reis, Janson, Christer, Olafsdottir, Inga Sif, Nisser, Katarina, Spetz-Nyström, Ulrike, Hägg, Gunilla, Lund, Gun-Marie, Jõgi, Rain, Laja, Hendrik, Ulst, Katrin, Zobel, Vappu, Lill, Toomas-Julius, Koul, Parvaiz A., Malik, Sajjad, Hakim, Nissar A., Khan, Umar Hafiz, Chowgule, Rohini, Shetye, Vasant, Raphael, Jonelle, Almeda, Rosel, Tawde, Mahesh, Tadvi, Rafiq, Katkar, Sunil, Kadam, Milind, Dhanawade, Rupesh, Ghurup, Umesh, Harrabi, Imed, Denguezli, Myriam, Tabka, Zouhair, Daldoul, Hager, Boukheroufa, Zaki, Chouikha, Firas, Khalifa, Wahbi Belhaj, Roa, Camilo C., Ayuyao, Fernando G., Tady, Cecil Z., Tan, Daniel T., Banal-Yang, Sylvia, Balanag, Vincent M., Jr., Reyes, Maria Teresita N., Juvekar, Sanjay, Hirve, Siddhi, Sambhudas, Somnath, Chaidhary, Bharat, Tambe, Meera, Pingale, Savita, Umap, Arati, Umap, Archana, Shelar, Nitin, Devchakke, Sampada, Chaudhary, Sharda, Bondre, Suvarna, Walke, Savita, Gawhane, Ashleshsa, Sapkal, Anil, Argade, Rupali, Gaikwad, Vijay, Salvi, Sundeep, Brashier, Bill, Londhe, Jyoti, Madas, Sapna, Obaseki, Daniel, Erhabor, Gregory, Awopeju, Olayemi, Adewole, Olufemi, Horner, Andreas, Kaiser, Bernhard, McBurnie, Mary Ann, Buist, A. Sonia, Gnatiuc, Luisa, Bateman, Eric D., and Burney, Peter

Published
2019
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3. The association of spirometric small airways obstruction with respiratory symptoms, cardiometabolic diseases, and quality of life : results from the Burden of Obstructive Lung Disease (BOLD) study

Author

Knox-Brown, Ben, Patel, Jaymini, Potts, James, Ahmed, Rana, Aquart-Stewart, Althea, Barbara, Cristina, Buist, A. Sonia, Cherkaski, Hamid Hacene, Denguezli, Meriam, Elbiaze, Mohammed, Erhabor, Gregory E., Franssen, Frits M. E., Al Ghobain, Mohammed, Gislason, Thorarinn, Janson, Christer, Kocabas, Ali, Mannino, David, Marks, Guy, Mortimer, Kevin, Nafees, Asaad Ahmed, Obaseki, Daniel, Paraguas, Stefanni Nonna M., Loh, Li Cher, Rashid, Abdul, Salvi, Sundeep, Seemungal, Terence, Studnicka, Michael, Tan, Wan C., Wouters, Emiel F. M., Abozid, Hazim, Mueller, Alexander, Burney, Peter, Amaral, Andre F. S., Knox-Brown, Ben, Patel, Jaymini, Potts, James, Ahmed, Rana, Aquart-Stewart, Althea, Barbara, Cristina, Buist, A. Sonia, Cherkaski, Hamid Hacene, Denguezli, Meriam, Elbiaze, Mohammed, Erhabor, Gregory E., Franssen, Frits M. E., Al Ghobain, Mohammed, Gislason, Thorarinn, Janson, Christer, Kocabas, Ali, Mannino, David, Marks, Guy, Mortimer, Kevin, Nafees, Asaad Ahmed, Obaseki, Daniel, Paraguas, Stefanni Nonna M., Loh, Li Cher, Rashid, Abdul, Salvi, Sundeep, Seemungal, Terence, Studnicka, Michael, Tan, Wan C., Wouters, Emiel F. M., Abozid, Hazim, Mueller, Alexander, Burney, Peter, and Amaral, Andre F. S.

Abstract

Background Spirometric small airways obstruction (SAO) is common in the general population. Whether spirometric SAO is associated with respiratory symptoms, cardiometabolic diseases, and quality of life (QoL) is unknown. Methods Using data from the Burden of Obstructive Lung Disease study (N = 21,594), we defined spirometric SAO as the mean forced expiratory flow rate between 25 and 75% of the FVC (FEF25-75) less than the lower limit of normal (LLN) or the forced expiratory volume in 3 s to FVC ratio (FEV3/FVC) less than the LLN. We analysed data on respiratory symptoms, cardiometabolic diseases, and QoL collected using standardised questionnaires. We assessed the associations with spirometric SAO using multivariable regression models, and pooled site estimates using random effects meta-analysis. We conducted identical analyses for isolated spirometric SAO (i.e. with FEV1/FVC ≥ LLN). Results Almost a fifth of the participants had spirometric SAO (19% for FEF25-75; 17% for FEV3/FVC). Using FEF25-75, spirometric SAO was associated with dyspnoea (OR = 2.16, 95% CI 1.77–2.70), chronic cough (OR = 2.56, 95% CI 2.08–3.15), chronic phlegm (OR = 2.29, 95% CI 1.77–4.05), wheeze (OR = 2.87, 95% CI 2.50–3.40) and cardiovascular disease (OR = 1.30, 95% CI 1.11–1.52), but not hypertension or diabetes. Spirometric SAO was associated with worse physical and mental QoL. These associations were similar for FEV3/FVC. Isolated spirometric SAO (10% for FEF25-75; 6% for FEV3/FVC), was also associated with respiratory symptoms and cardiovascular disease. Conclusion Spirometric SAO is associated with respiratory symptoms, cardiovascular disease, and QoL. Consideration should be given to the measurement of FEF25-75 and FEV3/FVC, in addition to traditional spirometry parameters.

Published
2023
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4. Chronic airflow obstruction and ambient particulate air pollution

Author

Amaral, Andre F. S., Burney, Peter G. J., Patel, Jaymini, Minelli, Cosetta, Mejza, Filip, Mannino, David M., Seemungal, Terence A. R., Mahesh, Padukudru Anand, Lo, Li Cher, Janson, Christer, Juvekar, Sanjay, Denguezli, Meriam, Harrabi, Imed, Wouters, Emiel F. M., Cherkaski, Hamid, Mortimer, Kevin, Jogi, Rain, Bateman, Eric D., Fuertes, Elaine, Al Ghobain, Mohammed, Tan, Wan, Obaseki, Daniel O., El Sony, Asma, Studnicka, Michael, Aquart-Stewart, Althea, Koul, Parvaiz, Lawin, Herve, Nafees, Asaad Ahmed, Awopeju, Olayemi, Erhabor, Gregory E., Gislason, Thorarinn, Welte, Tobias, Gulsvik, Amund, Nielsen, Rune, Gnatiuc, Louisa, Kocabas, Ali, Marks, Guy B., Sooronbaev, Talant, Mbatchou Ngahane, Bertrand Hugo, Barbara, Cristina, Buist, A. Sonia, Amaral, Andre F. S., Burney, Peter G. J., Patel, Jaymini, Minelli, Cosetta, Mejza, Filip, Mannino, David M., Seemungal, Terence A. R., Mahesh, Padukudru Anand, Lo, Li Cher, Janson, Christer, Juvekar, Sanjay, Denguezli, Meriam, Harrabi, Imed, Wouters, Emiel F. M., Cherkaski, Hamid, Mortimer, Kevin, Jogi, Rain, Bateman, Eric D., Fuertes, Elaine, Al Ghobain, Mohammed, Tan, Wan, Obaseki, Daniel O., El Sony, Asma, Studnicka, Michael, Aquart-Stewart, Althea, Koul, Parvaiz, Lawin, Herve, Nafees, Asaad Ahmed, Awopeju, Olayemi, Erhabor, Gregory E., Gislason, Thorarinn, Welte, Tobias, Gulsvik, Amund, Nielsen, Rune, Gnatiuc, Louisa, Kocabas, Ali, Marks, Guy B., Sooronbaev, Talant, Mbatchou Ngahane, Bertrand Hugo, Barbara, Cristina, and Buist, A. Sonia

Abstract

Smoking is the most well-established cause of chronic airflow obstruction (CAO) but particulate air pollution and poverty have also been implicated. We regressed sex-specific prevalence of CAO from 41 Burden of Obstructive Lung Disease study sites against smoking prevalence from the same study, the gross national income per capita and the local annual mean level of ambient particulate matter (PM2.5) using negative binomial regression. The prevalence of CAO was not independently associated with PM2.5 but was strongly associated with smoking and was also associated with poverty. Strengthening tobacco control and improved understanding of the link between CAO and poverty should be prioritised.

Published
2021
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5. COPD: Should Diagnosis Match Physiology?

Author

Zhong, NanShan, Liu, Shengming, Lu, Jiachun, Ran, Pixin, Wang, Dali, Zheng, Jingping, Zhou, Yumin, Kocabaş, Ali, Hancioglu, Attila, Hanta, Ismail, Kuleci, Sedat, Turkyilmaz, Ahmet Sinan, Umut, Sema, Unalan, Turgay, Studnicka, Michael, Dawes, Torkil, Lamprecht, Bernd, Sator, Lea, Bateman, Eric, Jithoo, Anamika, Adams, Desiree, Barnes, Edward, Freeman, Jasper, Hayes, Anton, Hlengwa, Sipho, Johannisen, Christine, Koopman, Mariana, Louw, Innocentia, Ludick, Ina, Olckers, Alta, Ryck, Johanna, Storbeck, Janita, Gislason, Thorarinn, Benedikdtsdottir, Bryndis, Jörundsdottir, Kristin, Gudmundsdottir, Lovisa, Gudmundsdottir, Sigrun, Gundmundsson, Gunnar, Nizankowska-Mogilnicka, Ewa, Frey, Jakub, Harat, Rafal, Mejza, Filip, Nastalek, Pawel, Pajak, Andrzej, Skucha, Wojciech, Szczeklik, Andrzej, Twardowska, Magda, Welte, Tobias, Bodemann, Isabelle, Geldmacher, Henning, Schweda-Linow, Alexandra, Gulsvik, Amund, Endresen, Tina, Svendsen, Lene, Tan, Wan C., Wang, Wen, Mannino, David M., Cain, John, Copeland, Rebecca, Hazen, Dana, Methvin, Jennifer, Dantes, Renato B., Amarillo, Lourdes, Berratio, Lakan U., Fernandez, Lenora C., Francisco, Norberto A., Garcia, Gerard S., de Guia, Teresita S., Idolor, Luisito F., Naval, Sullian S., Reyes, Thessa, Roa, Camilo C., Jr, Sanchez, Ma. Flordeliza, Simpao, Leander P., Jenkins, Christine, Marks, Guy, Bird, Tessa, Espinel, Paola, Hardaker, Kate, Toelle, Brett, Burney, Peter G.J., Amor, Caron, Potts, James, Tumilty, Michael, McLean, Fiona, Wouters, E.F.M., Wesseling, G.J., Bárbara, Cristina, Rodrigues, Fátima, Dias, Hermínia, Cardoso, João, Almeida, João, Matos, Maria João, Simão, Paula, Santos, Moutinho, Ferreira, Reis, Janson, Christer, Olafsdottir, Inga Sif, Nisser, Katarina, Spetz-Nyström, Ulrike, Hägg, Gunilla, Lund, Gun-Marie, Jõgi, Rain, Laja, Hendrik, Ulst, Katrin, Zobel, Vappu, Lill, Toomas-Julius, Koul, Parvaiz A., Malik, Sajjad, Hakim, Nissar A., Khan, Umar Hafiz, Chowgule, Rohini, Shetye, Vasant, Raphael, Jonelle, Almeda, Rosel, Tawde, Mahesh, Tadvi, Rafiq, Katkar, Sunil, Kadam, Milind, Dhanawade, Rupesh, Ghurup, Umesh, Harrabi, Imed, Denguezli, Myriam, Tabka, Zouhair, Daldoul, Hager, Boukheroufa, Zaki, Chouikha, Firas, Khalifa, Wahbi Belhaj, Roa, Camilo C., Ayuyao, Fernando G., Tady, Cecil Z., Tan, Daniel T., Banal-Yang, Sylvia, Balanag, Vincent M., Jr, Reyes, Maria Teresita N., Dantes, Renato. B., Juvekar, Sanjay, Hirve, Siddhi, Sambhudas, Somnath, Chaidhary, Bharat, Tambe, Meera, Pingale, Savita, Umap, Arati, Umap, Archana, Shelar, Nitin, Devchakke, Sampada, Chaudhary, Sharda, Bondre, Suvarna, Walke, Savita, Gawhane, Ashleshsa, Sapkal, Anil, Argade, Rupali, Gaikwad, Vijay, Salvi, Sundeep, Brashier, Bill, Londhe, Jyoti, Madas, Sapna, Obaseki, Daniel, Erhabor, Gregory, Awopeju, Olayemi, Adewole, Olufemi, Horner, Andreas, and Buist, A. Sonia

Published
2020
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8. Chronic airflow obstruction and ambient particulate air pollution

Author

Amaral, Andre F S, primary, Burney, Peter G J, additional, Patel, Jaymini, additional, Minelli, Cosetta, additional, Mejza, Filip, additional, Mannino, David M, additional, Seemungal, Terence A R, additional, Mahesh, Padukudru Anand, additional, Lo, Li Cher, additional, Janson, Christer, additional, Juvekar, Sanjay, additional, Denguezli, Meriam, additional, Harrabi, Imed, additional, Wouters, Emiel F M, additional, Cherkaski, Hamid, additional, Mortimer, Kevin, additional, Jogi, Rain, additional, Bateman, Eric D, additional, Fuertes, Elaine, additional, Al Ghobain, Mohammed, additional, Tan, Wan, additional, Obaseki, Daniel O, additional, El Sony, Asma, additional, Studnicka, Michael, additional, Aquart-Stewart, Althea, additional, Koul, Parvaiz, additional, Lawin, Herve, additional, Nafees, Asaad Ahmed, additional, Awopeju, Olayemi, additional, Erhabor, Gregory E, additional, Gislason, Thorarinn, additional, Welte, Tobias, additional, Gulsvik, Amund, additional, Nielsen, Rune, additional, Gnatiuc, Louisa, additional, Kocabas, Ali, additional, Marks, Guy B, additional, Sooronbaev, Talant, additional, Mbatchou Ngahane, Bertrand Hugo, additional, Barbara, Cristina, additional, and Buist, A Sonia, additional

Published
2021
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11. COPD : Should Diagnosis Match Physiology?

Author

Studnicka, Michael, Horner, Andreas, Sator, Lea, Buist, A. Sonia, Lamprecht, Bernd, Zhong, NanShan, Liu, Shengming, Lu, Jiachun, Ran, Pixin, Wang, Dali, Zheng, Jingping, Zhou, Yumin, Kocabas, Ali, Hancioglu, Attila, Hanta, Ismail, Kuleci, Sedat, Turkyilmaz, Ahmet Sinan, Umut, Sema, Unalan, Turgay, Dawes, Torkil, Bateman, Eric, Jithoo, Anamika, Adams, Desiree, Barnes, Edward, Freeman, Jasper, Hayes, Anton, Hlengwa, Sipho, Johannisen, Christine, Koopman, Mariana, Louw, Innocentia, Ludick, Ina, Olckers, Alta, Ryck, Johanna, Storbeck, Janita, Gislason, Thorarinn, Benedikdtsdottir, Bryndis, Jorundsdottir, Kristin, Gudmundsdottir, Lovisa, Gudmundsdottir, Sigrun, Gundmundsson, Gunnar, Nizankowska-Mogilnicka, Ewa, Frey, Jakub, Harat, Rafal, Mejza, Filip, Nastalek, Pawel, Pajak, Andrzej, Skucha, Wojciech, Szczeklik, Andrzej, Twardowska, Magda, Welte, Tobias, Bodemann, Isabelle, Geldmacher, Henning, Schweda-Linow, Alexandra, Gulsvik, Amund, Endresen, Tina, Svendsen, Lene, Tan, Wan C., Wang, Wen, Mannino, David M., Cain, John, Copeland, Rebecca, Hazen, Dana, Methvin, Jennifer, Amarillo, Lourdes, Berratio, Lakan U., Fernandez, Lenora C., Francisco, Norberto A., Garcia, Gerard S., de Guia, Teresita S., Idolor, Luisito F., Naval, Sullian S., Reyes, Thessa, Roa, Camilo C., Jr., Sanchez, Flordeliza, Simpao, Leander P., Jenkins, Christine, Marks, Guy, Bird, Tessa, Espinel, Paola, Hardaker, Kate, Toelle, Brett, Burney, Peter G. J., Amor, Caron, Potts, James, Tumilty, Michael, McLean, Fiona, Wouters, E. F. M., Wesseling, G. J., Barbara, Cristina, Rodrigues, Fatima, Dias, Herminia, Cardoso, Joao, Almeida, Joao, Matos, Maria Joao, Simao, Paula, Santos, Moutinho, Ferreira, Reis, Janson, Christer, Olafsdottir, Inga Sif, Nisser, Katarina, Spetz-Nyström, Ulrike, Hägg, Gunilla, Lund, Gun-Marie, Jogi, Rain, Laja, Hendrik, Ulst, Katrin, Zobel, Vappu, Lill, Toomas-Julius, Koul, Parvaiz A., Malik, Sajjad, Hakim, Nissar A., Khan, Umar Hafiz, Chowgule, Rohini, Shetye, Vasant, Raphael, Jonelle, Almeda, Rosel, Tawde, Mahesh, Tadvi, Rafiq, Katkar, Sunil, Kadam, Milind, Dhanawade, Rupesh, Ghurup, Umesh, Harrabi, Imed, Denguezli, Myriam, Tabka, Zouhair, Daldoul, Hager, Boukheroufa, Zaki, Chouikha, Firas, Khalifa, Wahbi Belhaj, Roa, Camilo C., Ayuyao, Fernando G., Tady, Cecil Z., Tan, Daniel T., Banal-Yang, Sylvia, Balanag, Vincent M., Jr., Reyes, Maria Teresita N., Dantes, Renato. B., Juvekar, Sanjay, Hirve, Siddhi, Sambhudas, Somnath, Chaidhary, Bharat, Tambe, Meera, Pingale, Savita, Umap, Arati, Umap, Archana, Shelar, Nitin, Devchakke, Sampada, Chaudhary, Sharda, Bondre, Suvarna, Walke, Savita, Gawhane, Ashleshsa, Sapkal, Anil, Argade, Rupali, Gaikwad, Vijay, Salvi, Sundeep, Brashier, Bill, Londhe, Jyoti, Madas, Sapna, Obaseki, Daniel, Erhabor, Gregory, Awopeju, Olayemi, Adewole, Olufemi, Studnicka, Michael, Horner, Andreas, Sator, Lea, Buist, A. Sonia, Lamprecht, Bernd, Zhong, NanShan, Liu, Shengming, Lu, Jiachun, Ran, Pixin, Wang, Dali, Zheng, Jingping, Zhou, Yumin, Kocabas, Ali, Hancioglu, Attila, Hanta, Ismail, Kuleci, Sedat, Turkyilmaz, Ahmet Sinan, Umut, Sema, Unalan, Turgay, Dawes, Torkil, Bateman, Eric, Jithoo, Anamika, Adams, Desiree, Barnes, Edward, Freeman, Jasper, Hayes, Anton, Hlengwa, Sipho, Johannisen, Christine, Koopman, Mariana, Louw, Innocentia, Ludick, Ina, Olckers, Alta, Ryck, Johanna, Storbeck, Janita, Gislason, Thorarinn, Benedikdtsdottir, Bryndis, Jorundsdottir, Kristin, Gudmundsdottir, Lovisa, Gudmundsdottir, Sigrun, Gundmundsson, Gunnar, Nizankowska-Mogilnicka, Ewa, Frey, Jakub, Harat, Rafal, Mejza, Filip, Nastalek, Pawel, Pajak, Andrzej, Skucha, Wojciech, Szczeklik, Andrzej, Twardowska, Magda, Welte, Tobias, Bodemann, Isabelle, Geldmacher, Henning, Schweda-Linow, Alexandra, Gulsvik, Amund, Endresen, Tina, Svendsen, Lene, Tan, Wan C., Wang, Wen, Mannino, David M., Cain, John, Copeland, Rebecca, Hazen, Dana, Methvin, Jennifer, Amarillo, Lourdes, Berratio, Lakan U., Fernandez, Lenora C., Francisco, Norberto A., Garcia, Gerard S., de Guia, Teresita S., Idolor, Luisito F., Naval, Sullian S., Reyes, Thessa, Roa, Camilo C., Jr., Sanchez, Flordeliza, Simpao, Leander P., Jenkins, Christine, Marks, Guy, Bird, Tessa, Espinel, Paola, Hardaker, Kate, Toelle, Brett, Burney, Peter G. J., Amor, Caron, Potts, James, Tumilty, Michael, McLean, Fiona, Wouters, E. F. M., Wesseling, G. J., Barbara, Cristina, Rodrigues, Fatima, Dias, Herminia, Cardoso, Joao, Almeida, Joao, Matos, Maria Joao, Simao, Paula, Santos, Moutinho, Ferreira, Reis, Janson, Christer, Olafsdottir, Inga Sif, Nisser, Katarina, Spetz-Nyström, Ulrike, Hägg, Gunilla, Lund, Gun-Marie, Jogi, Rain, Laja, Hendrik, Ulst, Katrin, Zobel, Vappu, Lill, Toomas-Julius, Koul, Parvaiz A., Malik, Sajjad, Hakim, Nissar A., Khan, Umar Hafiz, Chowgule, Rohini, Shetye, Vasant, Raphael, Jonelle, Almeda, Rosel, Tawde, Mahesh, Tadvi, Rafiq, Katkar, Sunil, Kadam, Milind, Dhanawade, Rupesh, Ghurup, Umesh, Harrabi, Imed, Denguezli, Myriam, Tabka, Zouhair, Daldoul, Hager, Boukheroufa, Zaki, Chouikha, Firas, Khalifa, Wahbi Belhaj, Roa, Camilo C., Ayuyao, Fernando G., Tady, Cecil Z., Tan, Daniel T., Banal-Yang, Sylvia, Balanag, Vincent M., Jr., Reyes, Maria Teresita N., Dantes, Renato. B., Juvekar, Sanjay, Hirve, Siddhi, Sambhudas, Somnath, Chaidhary, Bharat, Tambe, Meera, Pingale, Savita, Umap, Arati, Umap, Archana, Shelar, Nitin, Devchakke, Sampada, Chaudhary, Sharda, Bondre, Suvarna, Walke, Savita, Gawhane, Ashleshsa, Sapkal, Anil, Argade, Rupali, Gaikwad, Vijay, Salvi, Sundeep, Brashier, Bill, Londhe, Jyoti, Madas, Sapna, Obaseki, Daniel, Erhabor, Gregory, Awopeju, Olayemi, and Adewole, Olufemi

Published
2020
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13. Overdiagnosis of COPD in Subjects With Unobstructed Spirometry A BOLD Analysis

Author

Sator, Lea, Horner, Andreas, Studnicka, Michael, Lamprecht, Bernd, Kaiser, Bernhard, McBurnie, Mary Ann, Buist, A. Sonia, Gnatiuc, Luisa, Mannino, David M., Janson, Christer, Bateman, Eric D., Burney, Peter, Zhong, NanShan, Liu, Shengming, Lu, Jiachun, Ran, Pixin, Wang, Dali, Zheng, Jingping, Zhou, Yumin, Kocabas, Ali, Hancioglu, Attila, Hanta, Ismail, Kuleci, Sedat, Turkyilmaz, Ahmet Sinan, Umut, Sema, Unalan, Turgay, Dawes, Torkil, Bateman, Eric, Jithoo, Anamika, Adams, Desiree, Barnes, Edward, Freeman, Jasper, Hayes, Anton, Hlengwa, Sipho, Johannisen, Christine, Koopman, Mariana, Louw, Innocentia, Ludick, Ina, Olckers, Alta, Ryck, Johanna, Storbeck, Janita, Gislason, Thorarinn, Benedikdtsdottir, Bryndis, Jorundsdottir, Kristin, Gudmundsdottir, Lovisa, Gudmundsdottir, Sigrun, Gundmundsson, Gunnar, Nizankowska-Mogilnicka, Ewa, Wouters, E. F. M., Wesseling, G. J., MUMC+: MA Longziekten (3), RS: NUTRIM - R3 - Respiratory & Age-related Health, Pulmonologie, MUMC+: MA Med Staf Spec Longziekten (9), and RS: CAPHRI - R5 - Optimising Patient Care

Subjects
COUNTRIES, SYMPTOMS, overtreatment, false positive diagnosis, ACCURACY, overdiagnosis, DIAGNOSIS, OBSTRUCTIVE PULMONARY-DISEASE, PREVALENCE, UNDERDIAGNOSIS, DEFINITIONS, SEVERITY, COPD, QUALITY, misdiagnosis
Abstract

BACKGROUND: There are several reports on underdiagnosis of COPD, while little is known about COPD overdiagnosis and overtreatment. We describe the overdiagnosis and the prevalence of spirometrically defined false positive COPD, as well as their relationship with overtreatment across 23 population samples in 20 countries participating in the BOLD Study between 2003 and 2012. METHODS: A false positive diagnosis of COPD was considered when participants reported a doctor's diagnosis of COPD, but postbronchodilator spirometry was unobstructed (FEV1/FVC > LLN). Additional analyses were performed using the fixed ratio criterion (FEV1/FVC

Published
2019

16. Determination of Attitudes of Turkish Thoracic Society Members on Exposure to Sexist Approach and Sexism in Business Life

Author

Ocakli, Birsen, primary, Yorgancioglu, Arzu, additional, Topcu, Füsun, additional, Köktürk, Nurdan, additional, Altınöz, Hilal, additional, Yasin, Yesim, additional, Genc Kuzuca, İlknur, additional, Duru, Serap, additional, Ozari Yildirim, Elif, additional, Sevim, Tulin, additional, Tekgul, Serpil, additional, Acarturk Tuncay, Eylem, additional, Gungor, Sinem, additional, Goktas, Basak, additional, Yigiter Senol, Yesim, additional, Atinkaya Ozturk, Cansel, additional, Ozmen, Ipek, additional, Pinar Tastan, Cagla, additional, Us Dulger, Seyhan, additional, Uzaslan, Esra, additional, Erboy, Fatma, additional, Aksoy, Emine, additional, Yildiz Gulhan, Pinar, additional, Kocabas, Ali, additional, Gemicioglu, Bilun, additional, Topcu, Salih, additional, Altinisik, Goksel, additional, Celik, Pinar, additional, and Women Lung Care Workşng Group, Tts, additional

Published
2018
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19. Sarkoidozlu Hastada Gelişen Masif Pulmoner Tromboembolizm: Bir Olgu Nedeni İle

Author

Hanta, Ismail, EZGI OZYILMAZ, Baydar, Oya, Kuleci, Sedat, and Kocabas, Ali

Subjects
Massive pulmonary embolism,sarcoidosis, Massive pulmonary embolism, lcsh:R5-920, lcsh:R, lcsh:Medicine, sarcoidosis, Masif pulmoner tromboemboli,sarkoidoz, lcsh:Medicine (General)
Abstract

Although sarcoidosis is not a well known risk factor of pulmonary thromboembolism, recent investigations shows increased risk of pulmonary thromboembolism in these patients with the lack of any other risk factor. In this case report, massive pulmonary embolism was presented in a forty seven years old female patient who is followed up under metilprednisolon therapy due to sarcoidosis for five months. This patient was underlined because of that sarcoidosis may be a potential risk factor of pulmonary thromboembolism and must be kept in mind at the patients with sarcoidosis and acute deletoration. Keywords, Sarkoidoz, pulmoner tromboemboli için bilinen bir risk faktörü olmamakla birlikte son yıllarda bilinen başka risk faktörü olmaksızın sarkoidozlu hastalarda pulmoner tromboemboli gelişimi ile ilgili yeni veriler bildirilmektedir. Bu sunumda, 47 yaşında sarkoidoz tanısıyla beş aydır metilprednizolon tedavisi altında takip edilmekte olan kadın hastada gelişen bir masif tromboembolizm olgusu bildirilmiştir. Bu olgu ile, sarkoidozun pulmoner tromboembolinin risk faktörlerinden biri olabileceği ve takip altındaki sarkoidozlu hastalarda klinik bozulmanın ayırıcı tanısında pulmoner tromboembolinin de akılda tutulması gerekliliği düşünülmüştür.

Published
2011

23. Chronic obstructive pulmonary disease mortality and prevalence : the associations with smoking and poverty: a BOLD analysis-authors' reply

Author

Burney, Peter, Kato, Bernet, Janson, Christer, Mannino, David, Studnicka, Michael, Tan, Wan, Bateman, Eric, Kocabas, Ali, Vollmer, William M., Gislason, Thorarrin, Marks, Guy, Koul, Parvaiz A., Gnatiuc, Louisa, Buist, Sonia, Burney, Peter, Kato, Bernet, Janson, Christer, Mannino, David, Studnicka, Michael, Tan, Wan, Bateman, Eric, Kocabas, Ali, Vollmer, William M., Gislason, Thorarrin, Marks, Guy, Koul, Parvaiz A., Gnatiuc, Louisa, and Buist, Sonia

Published
2014
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24. Chronic obstructive pulmonary disease mortality and prevalence : the associations with smoking and poverty-a BOLD analysis

Author

Burney, Peter, Jithoo, Anamika, Kato, Bernet, Janson, Christer, Mannino, David, Nizankowska-Mogilnicka, Ewa, Studnicka, Michael, Tan, Wan, Bateman, Eric, Kocabas, Ali, Vollmer, William M., Gislason, Thorarrin, Marks, Guy, Koul, Parvaiz A., Harrabi, Imed, Gnatiuc, Louisa, Buist, Sonia, Burney, Peter, Jithoo, Anamika, Kato, Bernet, Janson, Christer, Mannino, David, Nizankowska-Mogilnicka, Ewa, Studnicka, Michael, Tan, Wan, Bateman, Eric, Kocabas, Ali, Vollmer, William M., Gislason, Thorarrin, Marks, Guy, Koul, Parvaiz A., Harrabi, Imed, Gnatiuc, Louisa, and Buist, Sonia

Abstract

Background Chronic obstructive pulmonary disease (COPD) is a commonly reported cause of death and associated with smoking. However, COPD mortality is high in poor countries with low smoking rates. Spirometric restriction predicts mortality better than airflow obstruction, suggesting that the prevalence of restriction could explain mortality rates attributed to COPD. We have studied associations between mortality from COPD and low lung function, and between both lung function and death rates and cigarette consumption and gross national income per capita (GNI). Methods National COPD mortality rates were regressed against the prevalence of airflow obstruction and spirometric restriction in 22 Burden of Obstructive Lung Disease (BOLD) study sites and against GNI, and national smoking prevalence. The prevalence of airflow obstruction and spirometric restriction in the BOLD sites were regressed against GNI and mean pack years smoked. Results National COPD mortality rates were more strongly associated with spirometric restriction in the BOLD sites (<60 years: men r(s)=0.73, p=0.0001; women r(s)=0.90, p<0.0001; 60+ years: men r(s)=0.63, p=0.0022; women r(s)=0.37, p=0.1) than obstruction (<60 years: men r(s)=0.28, p=0.20; women r(s)=0.17, p<0.46; 60+ years: men r(s)=0.28, p=0.23; women r(s)=0.22, p=0.33). Obstruction increased with mean pack years smoked, but COPD mortality fell with increased cigarette consumption and rose rapidly as GNI fell below US$ 15 000. Prevalence of restriction was not associated with smoking but also increased rapidly as GNI fell below US$ 15 000. Conclusions Smoking remains the single most important cause of obstruction but a high prevalence of restriction associated with poverty could explain the high 'COPD' mortality in poor countries.

Published
2014
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25. State of the World 2004; Special Focus: The Consumer Society

Author

Kocabas, Ali and Rutsch, Horst

Subjects
State of the World 2004, Special Focus: The Consumer Society (Book) -- Halweil, Brian -- Mastny, Lisa, Books -- Book reviews, International relations, Political science
Abstract

State of the World 2004 Special Focus: The Consumer Society Brian Halweil and Lisa Mastny, Project Directors Published by W.W. Norton/Worldwatch Institute, 2004 245 pp., ISBN 0-393-32539-3 Good Stuff? A [...]

Published
2004

30. The Prevalence Of Reported Cardiovascular Disease In Subjects With Non-Reversible Airways Obstruction - Findings From The Multi-Center Population-Based Burden Of Obstructive Lung Disease (BOLD) Study

Author

Studnicka, Michael, primary, McBurnie, Mary A., additional, Tan, Wan C., additional, Gulsvik, Amund, additional, Gislason, Thorarinn, additional, Kocabas, Ali, additional, Bateman, Erick, additional, Jithoo, Anamika, additional, Janson, Christer, additional, Jenkins, C, additional, Welte, Tobias, additional, Mejza, Filip, additional, Lamprecht, Bernd, additional, Wouters, Emiel F., additional, and Buist, A. Sonia, additional

Published
2011
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37. Early prediction of sarcoidosis prognosis with HLA typing: a 5 year follow-up study.

Author

Ozyilmaz E, Ozturk OG, Durmaz A, Othman Hasan O, Guzelbaba B, Seydaoglu G, Kuleci S, Hanta I, Erken E, and Kocabas A

Abstract

Background: A wide range of HLA-DR alleles have been associated with sarcoidosis either in terms of disease phenotype or extra pulmonary involvement, however the effect on non-resolution in different ethnic groups is not fully understood. The aim of this study was to investigate whether disease characterics and HLA-DRB1 alleles may early reflect non resolution in sarcoidosis. Methods: 91 patients who were diagnosed in Cukurova University Faculty of Medicine Department of Chest Diseases between 1993-2012 and were followed up until June 2017 were included in the study. All patients underwent HLA analysis by the Sequence Specific Oligonucleotide Prob (SSOP) method. Fifteen of them were excluded from the study group due to lost of follow-up (n=6) and not yet passed 5 years since diagnosis (n=9). Complete resolution at 5 th year was defined according to the predefined standard criteria (ACCESS). Results: The resolution rate was 51.3%. The HLA-DRB1*14 allele was significantly higher in patients without resolution (11.8 vs 1.3%)(p=0.006). According to multivariate logistic regression analysis the independent risk factors of non resolution were female gender (OR: 12.6; 95%CI: 2.1-74.9, p=0.005), HLA DRB1*14 allele (OR:51.9; 95%CI: 3.6-735.8, p=0.000), baseline TLCO<75%(predicted) (OR:3.8; 95%CI: 1.1-13.7, p=0.028), extra-pulmonary involvement (OR:3.7; 95%CI: 1.0-13.1, p=0.038) and advanced stage at baseline (OR: 8.3; 95%CI: 1.9-35.4, p=0.001). Conclusions: HLA-DRB1*14 alleles, lower baseline TLCO, advanced stage, female gender or the presence of extra-pulmonary involvement could predict long term non-resolution in sarcoidosis. Early prediction of long term prognosis may affect treatment decisions and avoid further deterioration in these patient groups. (Sarcoidosis Vasc Diffuse Lung Dis 2018; 35: 184-191) ., (Copyright: © 2018.)

Published
2018
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38. Could HLA-DR B1*11 allele be a clue for predicting extra-pulmonary sarcoidosis?

Author

Ozyilmaz E, Goruroglu Ozturk O, Yunsel D, Deniz A, Hanta I, Kuleci S, Seydaoglu G, Erken E, and Kocabas A

Subjects
Adult, Case-Control Studies, Female, Gene Frequency, Genetic Association Studies, Genetic Predisposition to Disease, HLA-DRB1 Chains immunology, Haplotypes, Humans, Logistic Models, Male, Middle Aged, Odds Ratio, Phenotype, Prospective Studies, Protective Factors, Risk Assessment, Risk Factors, Sarcoidosis diagnosis, Sarcoidosis ethnology, Sarcoidosis immunology, Turkey epidemiology, White People genetics, HLA-DRB1 Chains genetics, Sarcoidosis genetics
Abstract

Background: Several HLA-DR alleles have been described as a potential risk factor for sarcoidosis between distinct ethnic groups however the relationship between HLA-DR alleles and extra-pulmonary sarcoidosis (EPS) is still scarce., Objectives: The aim of this prospective study is to investigate the relationship between extra-pulmonary involvement and HLA-DR genetic analysis in Turkish patients with sarcoidosis., Methods: In this study, we HLA-typed sarcoidosis patients with and without extra-pulmonary involvement, and compared with healthy control subjects. The presence of EPS was evaluated with previously defined standard criteria (ACCESS) and only patients with definite and probable involvement were accepted as positive. Sequence Specific Oligonucletide Probes method was used for typing of HLA-DRB1 alleles from DNA samples in both groups., Results: The frequency of HLA DRB1*15 allele was more frequent in patients with sarcoidosis than controls (% 20.4 vs % 9.6)(pcorr=0.017). According to multivariate analysis (MVA), the presence of HLA DRB1*15 was indicated as an independent risk factor for sarcoidosis (OR:2.37; 95% CI: 1.31-4.30, p=0.004). Extra-pulmonary involvement was present in 39 patients (42.9 %). When the patients with and without extra-pulmonary involvement compared, HLADRB1*11 allele was significantly higher in patients without extra-pulmonary sarcoidosis which may be concluded as a protective allele for systemic involvement (%30.8 vs. %15.4)(p&lt;0.05). This result was also confirmed with the MVA (OR:0.35, %95 CI:0.15-0.84, p=0.018)., Conclusions: We demonstrated a strong positive link between the haplotype HLA DRB1*15 and sarcoidosis in a Turkish Caucasian population and a potential protective effect of HLA DRB1*11 from extra-pulmonary involvement of disease.

Published
2014

39. Risk factors for COPD spirometrically defined from the lower limit of normal in the BOLD project.

Author

Hooper R, Burney P, Vollmer WM, McBurnie MA, Gislason T, Tan WC, Jithoo A, Kocabas A, Welte T, and Buist AS

Subjects
Adult, Aged, Body Mass Index, Educational Status, Female, Humans, Male, Middle Aged, Multicenter Studies as Topic statistics & numerical data, Prevalence, Pulmonary Disease, Chronic Obstructive diagnosis, Pulmonary Disease, Chronic Obstructive etiology, Risk Factors, Smoking adverse effects, Smoking epidemiology, Spirometry methods, Tobacco Smoke Pollution adverse effects, Tobacco Smoke Pollution statistics & numerical data, Tuberculosis, Pulmonary complications, Tuberculosis, Pulmonary epidemiology, Pulmonary Disease, Chronic Obstructive epidemiology
Abstract

Chronic obstructive pulmonary disease (COPD) is predicted to become the third most common cause of death and disability worldwide by 2020. The prevalence of COPD defined by the lower limit of normal was estimated using high-quality spirometry in surveys of 14 populations aged ≥ 40 yrs. The strength and consistency of associations were assessed using random effects meta-analysis. Pack-years of smoking were associated with risk of COPD at each site. After adjusting for this effect, we still observed significant associations of COPD risk with age (OR 1.52 for a 10 yr age difference, 95% CI 1.35-1.71), body mass index in obese compared with normal weight (OR 0.50, 95% CI 0.37-0.67), level of education completed (OR 0.76, 95% CI 0.67-0.87), hospitalisation with a respiratory problem before age 10 yrs (OR 2.35, 95% CI 1.42-3.91), passive cigarette smoke exposure (OR 1.24, 95% CI 1.05-1.47), tuberculosis (OR 1.78, 95%CI 1.17-2.72) and a family history of COPD (OR 1.50, 95% CI 1.19-1.90). Although smoking is the most important risk factor for COPD, other risk factors are also important. More research is required to elucidate relevant risk factors in low- and middle-income countries where the greatest impact of COPD will occur.

Published
2012
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