Search

Copyright of Arquivos Brasileiros de Oftalmologia is the property of Arquivos Brasileiros de Oftalmologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Purpose: To evaluate the effect of long-term antiglaucomatous therapy on the meibomian glands by meibograpy. Materials and Methods: A total of 31 patients with unilateral ocular hypertension or glaucoma receiving antiglaucomatous medical treatment for at least 1 year were included in this study. The contralateral eyes were used as the control group. Invasive tear film break-up time (TF-BUT), fluorescein staining of the ocular surface, and Schirmer II test were performed in all subjects. Total eyelid score and meibomian gland secretion score were evaluated. Non-contact meibography were performed with the Sirius corneal topographic device. Results: There were 15 (48,4%) males and 16 (51,6%) females and the mean age was 57.9±9.8 years. While the TF-BUT (p<0.001) and Schirmer test (p<0.001) values were significantly lower in the glaucoma group compared to the control group, the ocular surface staining score (p=0.001), eyelid (p<0.001) and meibomian gland secretion (p<0.001) score were significantly higher. Meibomian gland loss area (p<0.001 for the both upper and lower eyelid) and meiboscore (p<0.001 for the upper and lower eyelid) were significantly higher in the glaucoma group. In correlation analysis number of antiglaucoma eye drops, daily benzalkonium chloride exposure was associated with ocular surface parameters and meiboscore. Disease duration was correlated with any of ocular surface parameters. Conclusion: Long-term topical anti-glaucoma treatment adversely affects the ocular surface and meibomian glands. We found that long-term use of topical antiglaucomatous drugs caused significant loss of meibomian glands by meibographic evaluation, as well as decreased ocular surface scores. [ABSTRACT FROM AUTHOR]

Copyright of MN Opthalmology / MN Oftalmoloji is the property of Medical Network and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of MN Opthalmology / MN Oftalmoloji is the property of Medical Network and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Purpose: To investigate the structural and functional changes of the retina and optic nerve in amblyopia.Methods: Eighteen patients with unilateral anisometropic amblyopia and 27 age-matched healthy controls were involved in this study. All patients underwent optical coherence tomography angiography (OCTA), pattern visual evoked potential (pVEP), and flash electroretinogram (fERG).Results: There was no statistically significant difference in terms of the foveal avascular zone (FAZ), perifoveal superficial density, whole superficial density, parafoveal deep density, perifoveal deep density among the eyes (P > 0 0.05). Significant differences were found only in superficial capillary plexus (SCP) vessel density in whole (P = 0.029) and parafoveal (P = 0.008) image. In electrophysiological tests, while VEP latencies of the amblyopic eyes increased compared to nonamblyopic eyes and controls (P = 0.027), VEP amplitudes decreased in amblyopic and nonamblyopic eyes compared to controls (P = 0.01), amplitudes of the rod (P = 0.027) and cones (P < 0.001) also decreased in amblyopic eyes compared to nonamblyopic and healthy eyes. When we assessed the correlation between the parameters of OCTA and electrophysiological test, only a significant correlation was found between parafoveal SCP vessel density and VEP amplitudes (r = 0.341).Conclusion: We found a significant decrease only in SCP vessel density of the OCTA parameters in amblyopic eyes compared to healthy eyes. We detected a significant relationship between parafoveal SCP vessel density and VEP parameters, which might be associated with the underlying pathophysiology of the amblyopia. [ABSTRACT FROM AUTHOR]

Purpose: To investigate optical coherence tomography angiography (OCTA) findings in patients with Behçet's disease (BD).Methods: Ninety-four eyes of 49 patients with BD and 53 eyes of 53 healthy subjects were included. Vascular density (VD), foveal avascular zone (FAZ) area, perifoveal capillary hypoperfusion, perifoveal capillary network disorganization, and FAZ irregularity were analyzed.Results: OCTA revealed retinal VD reduction and higher perifoveal capillary hypoperfusion, perifoveal capillary network disorganization and FAZ irregularity in ocular Behçet's compared to nonocular Behçet's (p = .000). However, compared to normal eyes, there was no difference between any OCTA measurements in nonocular BD patients. The mean area of FAZ was not different in any group (p = .266). In ocular Behçet, visual acuity was inversely correlated with FAZ area and FAZ irregularity.Conclusion: Retinal VD decreases and perifoveal microvascular network changes in ocular Behçet's. FAZ irregularity may be a more valuable marker than FAZ area for indicating ocular involvement. [ABSTRACT FROM AUTHOR]

Purpose: To investigate whether an association exists between obesity and optic nerve parameters. Methods: This was a prospective comparative study including 125 eyes of 63 obese and 122 eyes of 62 healthy pediatric subjects. Optic nerve measurements were performed using the Cirrus spectral domain optical coherence tomograph (SD-OCT). Results: The disc area, cup volume, mean and vertical C/D ratio, inferior and temporal RNFL thickness values were significantly higher in the control group than the obese group; however, age, sex, mean, superior and nasal RNFL thickness and rim area measurements were not statistically significantly different between the two groups. Age was significantly negatively correlated with temporal RNFL thickness in the obese group. Girls had significantly higher rim area, mean and superior RNFL thickness, and lower cup volume and vertical C/D ratio than boys in the obese group. Conclusion: These results could be helpful in the diagnosis and follow-up of obese children. [ABSTRACT FROM AUTHOR]

Purpose: The evaluation of anterior segment morphology using Pentacam Scheimpflug camera (Oculus, Germany) after Nd: YAG laser capsulotomy in patients with posterior capsule opacification Materials and Methods: Sixty-seven eyes of 67 patients performed Nd: YAG laser capsulotomy were recruited into our study. The changes of anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), central corneal thickness (CCT), and corneal volume (CV) were evaluated using Pentacam Scheimpflug camera before laser capsulotomy and after laser capsulotomy in the 1st week, 1st month, 3rd month and 6th month. The results were compared statistically. Results: The ACD and ACV values were significantly decreased in the 1st week when compared the values of prior to laser capsulotomy (p<0.05). However, the ACD and ACV values were not statistically different in the 1st month, 3rd month, and 6th month when compared the values of prior to laser capsulotomy. Similarly the ACA, CCT and CV values were not statistically different in any period when compared before the values of prior to laser capsulotomy. Conclusion: Our study reveal that laser capsulotomy does not affect the anterior segment parameters in the long term in spite of reduction in the ACD and ACV values in the 1st week. [ABSTRACT FROM AUTHOR]