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2,217 results on '"Kobayashi, Shu"'

5. Nanoparticle Catalysts in Flow Systems

Author

Miyamura, Hiroyuki, Kobayashi, Shū, Beller, Matthias, Series Editor, Dixneuf, Pierre H., Series Editor, Dupont, Jairton, Series Editor, Fürstner, Alois, Series Editor, Glorius, Frank, Series Editor, Gooßen, Lukas J., Series Editor, Nolan, Steven P., Series Editor, Okuda, Jun, Series Editor, Oro, Luis A., Series Editor, Willis, Michael, Series Editor, Zhou, Qi-Lin, Series Editor, and Kobayashi, Shū, editor

Published
2020
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6. Chiral Metal Nanoparticles for Asymmetric Catalysis

Author

Yasukawa, Tomohiro, Kobayashi, Shū, Beller, Matthias, Series Editor, Dixneuf, Pierre H., Series Editor, Dupont, Jairton, Series Editor, Fürstner, Alois, Series Editor, Glorius, Frank, Series Editor, Gooßen, Lukas J., Series Editor, Nolan, Steven P., Series Editor, Okuda, Jun, Series Editor, Oro, Luis A., Series Editor, Willis, Michael, Series Editor, Zhou, Qi-Lin, Series Editor, and Kobayashi, Shū, editor

Published
2020
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10. Sequential‐Flow Synthesis of Donepezil: A Green and Sustainable Strategy Featuring Heterogeneous Catalysis and Hydrogenation.

Author

Ishitani, Haruro, Sogo, Hideyuki, Furiya, Yuichi, and Kobayashi, Shu

Subjects
CONDENSATION reactions, HETEROGENEOUS catalysis, ADDITION reactions, ALZHEIMER'S disease, HETEROGENEOUS catalysts
Abstract

An atom‐economical sequential‐flow synthesis of donepezil, a widely prescribed drug for Alzheimer's disease, was accomplished using inexpensive, commercially available precursors. This achievement was made possible by reconfiguring the synthetic route to include only heterogeneous catalytic addition and condensation reactions, with a particular emphasis on skeletal transformation and bond formation through hydrogenation processes. Notably, water was the sole byproduct in this synthesis. A crucial aspect of this work was the development of appropriate continuous‐flow processes to achieve a one‐flow synthesis. This was accomplished by implementing in‐line treatments of the main reaction stream to eliminate inhibitory factors that could affect catalyst performance in the hydrogenation steps. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Recent Advances of Asymmetric Catalysis in Flow for Drug Discovery

Author

Saito, Yuki, Kobayashi, Shu, Bernstein, Peter R., Series Editor, Garner, Amanda L., Series Editor, Georg, Gunda I., Series Editor, Laufer, Stefan, Series Editor, Lowe, John A., Series Editor, Meanwell, Nicholas A., Series Editor, Saxena, Anil Kumar, Series Editor, Supuran, Claudiu T., Series Editor, Zhang, Ao, Series Editor, Tschammer, Nuska, Series Editor, Poulsen, Sally-Ann, Series Editor, Alcazar, Jesus, editor, de la Hoz, Antonio, editor, and Díaz-Ortiz, Angel, editor

Published
2021
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29. Chiral Alkaline Earth Metal Complexes in Asymmetric Catalysis

Author

Yamashita, Yasuhiro, Tsubogo, Tetsu, Kobayashi, Shū, Beller, M., Editorial Board Member, Dixneuf, P. H., Editorial Board Member, Dupont, J., Editorial Board Member, Fürstner, A., Editorial Board Member, Glorius, F., Editorial Board Member, Gooßen, L. J., Editorial Board Member, Ikariya, T., Editorial Board Member, Nolan, S. P., Editorial Board Member, Okuda, J., Editorial Board Member, Oro, L. A., Editorial Board Member, Willis, M., Editorial Board Member, Zhou, Q.-L., Editorial Board Member, Mikami, Koichi, editor, Brill, M., Book Editor, Deng, Y., Book Editor, Doyle, M. P., Book Editor, Feng, X., Book Editor, Hatano, M., Book Editor, Ishihara, K., Book Editor, Kobayashi, S., Book Editor, Kumagai, N., Book Editor, Liu, X., Book Editor, Paradies, J., Book Editor, Sha, Q., Book Editor, Shibasaki, M., Book Editor, Tsubogo, T., Book Editor, Wang, Z., Book Editor, and Yamashita, Y., Book Editor

Published
2018
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41. Enantioselective Organometallic Catalysis in Flow

Author

Ishitani, Haruro, Saito, Yuki, Kobayashi, Shū, Beller, Matthias, Series editor, Dixneuf, Pierre H., Series editor, Dupont, Jairton, Series editor, Fürstner, Alois, Series editor, Glorius, Frank, Series editor, Gooßen, Lukas J., Series editor, Ikariya, Takao, Series editor, Nolan, Steven P., Series editor, Okuda, Jun, Series editor, Oro, Luis A., Series editor, Willis, Michael, Series editor, Zhou, Qi-Lin, Series editor, and Noël, Timothy, editor

Published
2016
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44. Two Cases of Emphysematous Pyelonephritis Successfully Treated by Transurethral Catheterization

Author

TAKEMORI, Daigo, SATAKE, Hirofumi, and KOBAYASHI, Shu

Subjects
Emphysematous pyelonephritis, Transurethral catheterization, 494.9
Abstract

Emphysematous pyelonephritis (EPN) is a severe necrotic urinary tract infection accompanied by retention of gas in the kidney and areas around it. Formerly, emergency nephrectomy was the primary treatment, but the trend is shifting to treatment with maximum conservation of the kidney. In this report, two cases of EPN successfully treated by transurethral drainage are presented. The first case was in a 63-year-old woman with a history of poorly controlled diabetes. She arrived at the hospital by ambulance with primary symptoms of vomiting and trembling of the hands, and computed tomography (CT) revealed gas in the right renal calix. The second case was in a 61-year-old woman who arrived by ambulance with difficulty of body movement as the primary symptom, and CT revealed a calculus in the right ureter accompanied by right hydronephrosis and retention of gas in the right renal pelvis and right upper ureter. Both patients were diagnosed with EPN and treated by transurethral drainage rather than percutaneous drainage or nephrectomy because of their poor general condition. The treatment was successful. Along with percutaneous drainage, transurethral drainage is considered to be an option of surgical treatment for EPN.

Published
2022

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