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405 results on '"Kobayashi, Nozomu"'

1. Time series generation for option pricing on quantum computers using tensor network

Author

Kobayashi, Nozomu, Suimon, Yoshiyuki, and Miyamoto, Koichi

Subjects
Quantum Physics, Computer Science - Machine Learning, Quantitative Finance - Computational Finance
Abstract

Finance, especially option pricing, is a promising industrial field that might benefit from quantum computing. While quantum algorithms for option pricing have been proposed, it is desired to devise more efficient implementations of costly operations in the algorithms, one of which is preparing a quantum state that encodes a probability distribution of the underlying asset price. In particular, in pricing a path-dependent option, we need to generate a state encoding a joint distribution of the underlying asset price at multiple time points, which is more demanding. To address these issues, we propose a novel approach using Matrix Product State (MPS) as a generative model for time series generation. To validate our approach, taking the Heston model as a target, we conduct numerical experiments to generate time series in the model. Our findings demonstrate the capability of the MPS model to generate paths in the Heston model, highlighting its potential for path-dependent option pricing on quantum computers., Comment: 15 pages, 2 figures

Published
2024

3. The cross-sectional stock return predictions via quantum neural network and tensor network

Author

Kobayashi, Nozomu, Suimon, Yoshiyuki, Miyamoto, Koichi, and Mitarai, Kosuke

Subjects
Computer Science - Machine Learning, Quantitative Finance - Computational Finance, Quantum Physics
Abstract

In this paper, we investigate the application of quantum and quantum-inspired machine learning algorithms to stock return predictions. Specifically, we evaluate the performance of quantum neural network, an algorithm suited for noisy intermediate-scale quantum computers, and tensor network, a quantum-inspired machine learning algorithm, against classical models such as linear regression and neural networks. To evaluate their abilities, we construct portfolios based on their predictions and measure investment performances. The empirical study on the Japanese stock market shows the tensor network model achieves superior performance compared to classical benchmark models, including linear and neural network models. Though the quantum neural network model attains a lowered risk-adjusted excess return than the classical neural network models over the whole period, both the quantum neural network and tensor network models have superior performances in the latest market environment, which suggests the capability of the model's capturing non-linearity between input features., Comment: 19 pages, 7 figures

Published
2023
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4. Association between continuous cessation or reduction of drinking alcohol and improvement of multiple dysplastic lesions in patients with esophageal squamous cell carcinoma after endoscopic resection

Author

Hori, Keisuke, Katada, Chikatoshi, Okada, Hiroyuki, Katagiri, Atsushi, Matsuo, Yasumasa, Yokoyama, Tetsuji, Yano, Tomonori, Suzuki, Haruhisa, Shimizu, Yuichi, Furue, Yasuaki, Nakanishi, Hiroyoshi, Koike, Tomoyuki, Takizawa, Kohei, Hirao, Motohiro, Yoshii, Takako, Yamanouchi, Takenori, Kawakubo, Hirofumi, Kobayashi, Nozomu, Shimoda, Tadakazu, Ochiai, Atsushi, Ishikawa, Hideki, Yokoyama, Akira, and Muto, Manabu

Published
2024
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5. Adenoma with Pagetoid Spread

Author

Takamaru, Hiroyuki, Kobayashi, Nozomu, Sano, Yasushi, editor, Chiu, Philip, editor, Singh, Rajvinder, editor, Uedo, Noriya, editor, Goda, Kenichi, editor, and Katada, Chikatoshi, editor

Published
2024
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6. Prevalence of family history of cancer in the NC-CCAPH consortium of Japan

Author

Abe, Sarah Krull, Ihira, Hikaru, Minami, Tetsuji, Imatoh, Takuya, Inoue, Yosuke, Tsutsumimoto, Kota, Kobayashi, Nozomu, Kashima, Rena, Konishi, Maki, Doi, Takehiko, Teramoto, Masayuki, Kabe, Isamu, Lee, Sangyoon, Watanabe, Makoto, Dohi, Seitaro, Sakai, Yukie, Nishita, Yukiko, Morisaki, Naho, Tachimori, Hisateru, Kokubo, Yoshihiro, Yamaji, Taiki, Shimada, Hiroyuki, Mizoue, Tetsuya, Sawada, Norie, Tsugane, Shoichiro, Iwasaki, Motoki, and Inoue, Manami

Published
2023
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7. Endoscopic Removal of Premalignant Lesions Reduces Long-Term Colorectal Cancer Risk: Results From the Japan Polyp Study

Author

Sano, Yasushi, Hotta, Kinichi, Matsuda, Takahisa, Murakami, Yoshitaka, Fujii, Takahiro, Kudo, Shin-ei, Oda, Yasushi, Ishikawa, Hideki, Saito, Yutaka, Kobayashi, Nozomu, Sekiguchi, Masau, Ikematsu, Hiroaki, Katagiri, Atsushi, Konishi, Kazuo, Takeuchi, Yoji, Iishi, Hiroyasu, Igarashi, Masahiro, Kobayashi, Kiyonori, Sada, Miwa, Osera, Shozo, Shinohara, Tomoaki, Yamaguchi, Yuichiro, Hasuda, Kiwamu, Morishima, Toshitaka, Miyashiro, Isao, Shimoda, Tadakazu, Taniguchi, Hirokazu, Fujimori, Takahiro, Ajioka, Yoichi, and Yoshida, Shigeaki

Published
2024
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8. The $O(N)$ model with $\phi^6$ potential in ${\mathbb R}^2 \times {\mathbb R}^+$

Author

Herzog, Christopher P. and Kobayashi, Nozomu

Subjects
High Energy Physics - Theory, Condensed Matter - Statistical Mechanics
Abstract

We study the large $N$ limit of $O(N)$ scalar field theory with classically marginal $\phi^6$ interaction in three dimensions in the presence of a planar boundary. This theory has an approximate conformal invariance at large $N$. We find different phases of the theory corresponding to different boundary conditions for the scalar field. Computing a one loop effective potential, we examine the stability of these different phases. The potential also allows us to determine a boundary anomaly coefficient in the trace of the stress tensor. We further compute the current and stress-tensor two point functions for the Dirichlet case and decompose them into boundary and bulk conformal blocks. The boundary limit of the stress tensor two point function allows us to compute the other boundary anomaly coefficient. Both anomaly coefficients depend on the approximately marginal $\phi^6$ coupling., Comment: 36pages, 6 figures

Published
2020

9. Regge OPE blocks and light-ray operators

Author

Kobayashi, Nozomu, Nishioka, Tatsuma, and Okuyama, Yoshitaka

Subjects
High Energy Physics - Theory
Abstract

We consider the structure of the operator product expansion (OPE) in conformal field theory by employing the OPE block formalism. The OPE block acted on the vacuum is promoted to an operator and its implications are examined on a non-vacuum state. We demonstrate that the OPE block is dominated by a light-ray operator in the Regge limit, which reproduces precisely the Regge behavior of conformal blocks when used inside scalar four-point functions. Motivated by this observation, we propose a new form of the OPE block, called the light-ray channel OPE block that has a well-behaved expansion dominated by a light-ray operator in the Regge limit. We also show that the two OPE blocks have the same asymptotic form in the Regge limit and confirm the assertion that the Regge limit of a pair of spacelike-separated operators in a Minkowski patch is equivalent to the OPE limit of a pair of timelike-separated operators associated with the original pair in a different Minkowski patch., Comment: 53 pages, 12 figures, v3: typos corrected

Published
2020
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10. The gravity dual of Lorentzian OPE blocks

Author

Chen, Heng-Yu, Chen, Lung-Chuan, Kobayashi, Nozomu, and Nishioka, Tatsuma

Subjects
High Energy Physics - Theory
Abstract

We consider the operator product expansion (OPE) structure of scalar primary operators in a generic Lorentzian CFT and its dual description in a gravitational theory with one extra dimension. The OPE can be decomposed into certain bi-local operators transforming as the irreducible representations under conformal group, called the OPE blocks. We show the OPE block is given by integrating a higher spin field along a geodesic in the Lorentzian AdS space-time when the two operators are space-like separated. When the two operators are time-like separated however, we find the OPE block has a peculiar representation where the dual gravitational theory is not defined on the AdS space-time but on a hyperboloid with an additional time coordinate and Minkowski space-time on its boundary. This differs from the surface Witten diagram proposal for the time-like OPE block, but in two dimensions we reproduce it consistently using a kinematical duality between a pair of time-like separated points and space-like ones., Comment: 40 pages + 10 pages of appendices, 7 figures, v2: typos corrected, minor changes, v3: typos corrected

Published
2019
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11. Nomogram as a novel predictive tool for lymph node metastasis in T1 colorectal cancer treated with endoscopic resection: a nationwide, multicenter study

Author

Kajiwara, Yoshiki, Oka, Shiro, Tanaka, Shinji, Nakamura, Takahiro, Saito, Shoichi, Fukunaga, Yosuke, Takamatsu, Manabu, Kawachi, Hiroshi, Hotta, Kinichi, Ikematsu, Hiroaki, Kojima, Motohiro, Saito, Yutaka, Yamada, Masayoshi, Kanemitsu, Yukihide, Sekine, Shigeki, Nagata, Shinji, Yamada, Kazutaka, Kobayashi, Nozomu, Ishihara, Soichiro, Saitoh, Yusuke, Matsuda, Kenji, Togashi, Kazutomo, Komori, Koji, Ishiguro, Megumi, Kuwai, Toshio, Okuyama, Takashi, Ohuchi, Akihiro, Ohnuma, Shinobu, Sakamoto, Kazuhiro, Sugai, Tamotsu, Katsumata, Kenji, Matsushita, Hiro-o, Yamano, Hiro-o, Eda, Hirotsugu, Uraoka, Toshio, Akimoto, Naohiko, Kobayashi, Hirotoshi, Ajioka, Yoichi, Sugihara, Kenichi, and Ueno, Hideki

Published
2023
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12. Towards a $C$-theorem in defect CFT

Author

Kobayashi, Nozomu, Nishioka, Tatsuma, Sato, Yoshiki, and Watanabe, Kento

Subjects
High Energy Physics - Theory, Condensed Matter - Statistical Mechanics
Abstract

We explore a $C$-theorem in defect conformal field theories (DCFTs) that unify all the known conjectures and theorems until now. We examine as a candidate $C$-function the additional contributions from conformal defects to the sphere free energy and the entanglement entropy across a sphere in a number of examples including holographic models. We find the two quantities are equivalent, when suitably regularized, for codimension-one defects (or boundaries), but differ by a universal constant term otherwise. Moreover, we find in a few field theoretic examples that the sphere free energy decreases but the entanglement entropy increases along a certain renormalization group (RG) flow triggered by a defect localized perturbation which is assumed to have a trivial IR fixed point without defects. We hence propose a $C$-theorem in DCFTs stating that the increment of the regularized sphere free energy due to the defect does not increase under any defect RG flow. We also provide a proof of our proposal in several holographic models of defect RG flows., Comment: 48 pages, 5 figures, v2: typos corrected, references added, minor changes

Published
2018
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13. Long-term Survival After Endoscopic Resection For Gastric Cancer: Real-world Evidence From a Multicenter Prospective Cohort

Author

Mashimo, Yumi, Ishigooka, Masahiro, Fukase, Kazutoshi, Mizuguchi, Yasuhiko, Suzuki, Haruhisa, Ono, Hiroyuki, Hirasawa, Toshiaki, Takeuchi, Yoji, Ishido, Kenji, Hoteya, Shu, Yano, Tomonori, Tanaka, Shinji, Toya, Yosuke, Nakagawa, Masahiro, Toyonaga, Takashi, Takemura, Kenichi, Hirasawa, Kingo, Matsuda, Mitsuru, Yamamoto, Hironori, Tsuji, Yosuke, Hashimoto, Satoru, Yuki, Maeda, Oyama, Tsuneo, Takenaka, Ryuta, Yamamoto, Yoshinobu, Naito, Yuji, Yamamoto, Katsumi, Kobayashi, Nozomu, Kawahara, Yoshiro, Hirano, Masaaki, Koizumi, Shigeto, Hori, Shinichiro, Tajika, Masahiro, Hikichi, Takuto, Yao, Kenshi, Yokoi, Chizu, Ohnita, Ken, Hisanaga, Yasuhiro, Sumiyoshi, Tetsuya, Kitamura, Shinji, Tanaka, Hisao, Shimoda, Ryo, Shimazu, Taichi, Takizawa, Kohei, Tanabe, Satoshi, Kondo, Hitoshi, Iishi, Hiroyasu, Ninomiya, Motoki, and Oda, Ichiro

Published
2023
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14. Final Analysis of Diagnostic Endoscopic Resection Followed by Selective Chemoradiotherapy for Stage I Esophageal Cancer: JCOG0508

Author

Mizuaswa, Junki, Takizawa, Kohei, Aoyama, Ikuo, Ishiyama, Akiyoshi, Kawata, Noboru, Kikuchi, Daisuke, Hanaoka, Noboru, Oda, Ichiro, Morita, Yoshinori, Tajika, Masahiro, Fujiwara, Junko, Yamamoto, Yoshinobu, Katada, Chikatoshi, Hori, Shinichiro, Doyama, Hisashi, Oyama, Tsuneo, Nebiki, Hiroko, Amagai, Kenji, Kubota, Yutaro, Inokuchi, Yasuhiro, Kobayashi, Nozomu, Suzuki, Takuto, Hirasawa, Kingo, Takeuchi, Toshihisa, Kadota, Tomohiro, Nihei, Keiji, Minashi, Keiko, Yano, Tomonori, Shimoda, Tadakazu, Fukuda, Haruhiko, and Muto, Manabu

Published
2023
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15. Endoscopic hand suturing using a modified through‐the‐scope needle holder for mucosal closure after colorectal endoscopic submucosal dissection: Prospective multicenter study (with video)

Author

Uozumi, Takeshi, primary, Abe, Seiichiro, additional, Mizuguchi, Yasuhiko, additional, Sekiguchi, Masau, additional, Toyoshima, Naoya, additional, Takamaru, Hiroyuki, additional, Yamada, Masayoshi, additional, Kobayashi, Nozomu, additional, Sadachi, Ryo, additional, Ito, Sayo, additional, Takada, Kazunori, additional, Kishida, Yoshihiro, additional, Imai, Kenichiro, additional, Hotta, Kinichi, additional, Ono, Hiroyuki, additional, and Saito, Yutaka, additional

Published
2024
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16. Spinning conformal defects

Author

Kobayashi, Nozomu and Nishioka, Tatsuma

Subjects
High Energy Physics - Theory
Abstract

We consider conformal defects with spins under the rotation group acting on the transverse directions. They are described in the embedding space formalism in a similar manner to spinning local operators, and their correlation functions with bulk and defect local operators are determined by the conformal symmetry. The operator product expansion (OPE) structure of spinning conformal defects is examined by decomposing it into the spinning defect OPE block that packages all the contribution from a conformal multiplet. The integral representation of the block derived in the shadow formalism is facilitated to deduce recursion relations for correlation functions of two spinning conformal defects. In simple cases, we construct spinning defect correlators by acting differential operators recursively on scalar defect correlators., Comment: 36 pages, v2: minor corrections, a reference and notes added, v3: typos corrected

Published
2018
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17. Observables in Inhomogeneous Ground States at Large Global Charge

Author

Hellerman, Simeon, Kobayashi, Nozomu, Maeda, Shunsuke, and Watanabe, Masataka

Subjects
High Energy Physics - Theory
Abstract

As a sequel to previous work, we extend the study of the ground state configuration of the $D=3$, Wilson-Fisher conformal $O(4)$ model. In this work, we prove that for generic ratios of two charge densities, $\rho_1/\rho_2$, the ground-state configuration is inhomogeneous and that the inhomogeneity expresses itself towards longer spatial periods. This is the direct extension of the similar statements we previously made for $\rho_1/\rho_2\ll 1$. We also compute, at fixed set of charges, $\rho_1,\, \rho_2$, the ground state energy and the two-point function(s) associated with this inhomogeneous configuration on the torus. The ground state energy was found to scale $(\rho_1+\rho_2)^{3/2}$, as dictated by dimensional analysis and similarly to the case of the $O(2)$ model. Unlike the case of the $O(2)$ model, the ground also strongly violates cluster decomposition in the large-volume, fixed-density limit, with a two-point function that is negative definite at antipodal points of the torus at leading order at large charge., Comment: 25 pages

Published
2018
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18. Operator product expansion for conformal defects

Author

Fukuda, Masayuki, Kobayashi, Nozomu, and Nishioka, Tatsuma

Subjects
High Energy Physics - Theory
Abstract

We study the operator product expansion (OPE) for scalar conformal defects of any codimension in CFT. The OPE for defects is decomposed into "defect OPE blocks", the irreducible representations of the conformal group, each of which packages the contribution from a primary operator and its descendants. We use the shadow formalism to deduce an integral representation of the defect OPE blocks. They are shown to obey a set of constraint equations that can be regarded as equations of motion for a scalar field propagating on the moduli space of the defects. By employing the Radon transform between the AdS space and the moduli space, we obtain a formula of constructing an AdS scalar field from the defect OPE block for a conformal defect of any codimension in a scalar representation of the conformal group, which turns out to be the Euclidean version of the HKLL formula. We also introduce a duality between conformal defects of different codimensions and prove the equivalence between the defect OPE block for codimension-two defects and the OPE block for a pair of local operators., Comment: 47 pages, v2: a reference added

Published
2017
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19. Optimal surveillance interval after piecemeal endoscopic mucosal resection for large colorectal neoplasia: a multicenter randomized controlled trial

Author

Nakajima, Takeshi, Sakamoto, Taku, Hori, Shinichiro, Yamada, Shinya, Ikematsu, Hiroaki, Harada, Keita, Chiu, Han-Mo, Kiriyama, Shinsuke, Michida, Tomoki, Hotta, Kinichi, Sakamoto, Naoto, Abe, Takashi, Chino, Akiko, Fukuzawa, Masakatsu, Kobayashi, Nozomu, Fukase, Kazutoshi, Matsuda, Takahisa, Murakami, Yoshitaka, Ishikawa, Hideki, and Saito, Yutaka

Published
2022
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21. Field Effect of Alcohol, Cigarette Smoking, and Their Cessation on the Development of Multiple Dysplastic Lesions and Squamous Cell Carcinoma: A Long-term Multicenter Cohort Study

Author

Kaneko, Kazuhiro, Morita, Shuko, Funakoshi, Makiko, Horimatsu, Takahiro, Takahashi, Mari, Suzuki, Haruhisa, Abiko, Satoshi, Takemura, Kenichi, Nakanishi, Hiroyoshi, Saito, Masahiro, Ara, Nobuyuki, Kakushima, Naomi, Tanaka, Masaki, Hori, Keisuke, Tsuda, Takashi, Muto, Manabu, Katada, Chikatoshi, Yokoyama, Tetsuji, Yano, Tomonori, Oda, Ichiro, Ezoe, Yasumasa, Tanabe, Satoshi, Shimizu, Yuichi, Doyama, Hisashi, Koike, Tomoyuki, Takizawa, Kohei, Hirao, Motohiro, Okada, Hiroyuki, Ogata, Takashi, Katagiri, Atsushi, Yamanouchi, Takenori, Matsuo, Yasumasa, Kawakubo, Hirofumi, Omori, Tai, Kobayashi, Nozomu, Shimoda, Tadakazu, Ochiai, Atsushi, Ishikawa, Hideki, Baba, Kiichiro, Amanuna, Yusuke, Yokoyama, Akira, and Ohashi, Shinya

Published
2022
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22. A Note on Inhomogeneous Ground States at Large Global Charge

Author

Hellerman, Simeon, Kobayashi, Nozomu, Maeda, Shunsuke, and Watanabe, Masataka

Subjects
High Energy Physics - Theory
Abstract

In this note we search for the ground state, in infinite volume, of the $D=3$ Wilson-Fisher conformal $O(4)$ model, at nonzero values of the two independent charge densities $\rho_{1,2}$. Using an effective theory valid on scales longer than the scale defined by the charge density, we show that the ground-state configuration is inhomogeneous for generic ratios $\rho_1 / \rho_2$. This result confirms, within the context of a well-defined effective theory, a recent no-go result of Alvarez-Gaume' et al. We also show that any spatially periodic ground state solutions have an energetic preference towards longer periods, within some range of $\rho_1 / \rho_2$ containing a neighborhood of zero. This suggests that the scale of variation of the ground state solution in finite volume will be the infrared scale, and that the use of the effective theory at large charge in finite volume is self-consistent., Comment: 13 pages, LaTeX

Published
2017
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23. Proportions and characteristics of interval cancer in annual fecal immunochemical test screening and postcolonoscopy colorectal cancer: Results from a Japanese multicenter prospective study using questionnaires, the C‐DETECT study

Author

Sekiguchi, Masau, primary, Kishida, Yoshihiro, additional, Ikematsu, Hiroaki, additional, Konno, Maki, additional, Mizuguchi, Yasuhiko, additional, Hotta, Kinichi, additional, Imai, Kenichiro, additional, Ito, Sayo, additional, Takada, Kazunori, additional, Shiomi, Akio, additional, Yasui, Hirofumi, additional, Tsukamoto, Shunsuke, additional, Hirano, Hidekazu, additional, Kobayashi, Nozomu, additional, Saito, Yutaka, additional, Inaba, Atsushi, additional, Shinmura, Kensuke, additional, Konishi, Jun, additional, Ozawa, Heita, additional, Fujita, Shin, additional, Murakami, Yoshitaka, additional, and Matsuda, Takahisa, additional

Published
2024
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24. Short‐term and long‐term outcomes of submucosal dissection for residual or recurrent colorectal tumors after endoscopic resection: Analysis of a multicenter prospective study.

Author

Tanaka, Hirohito, primary, Uraoka, Toshio, additional, Kobayashi, Nozomu, additional, Ohata, Ken, additional, Takeuchi, Yoji, additional, Chino, Akiko, additional, Yamada, Masayoshi, additional, Tsuji, Yosuke, additional, Hotta, Kinichi, additional, Harada, Keita, additional, Ikematsu, Hiroaki, additional, Murakami, Takashi, additional, Tsuji, Shigetsugu, additional, Katagiri, Atsushi, additional, Hori, Shinichiro, additional, Michida, Tomoki, additional, Suzuki, Takuto, additional, Fukuzawa, Masakatsu, additional, Kiriyama, Shinsuke, additional, Fukase, Kazutoshi, additional, Murakami, Yoshitaka, additional, Ishikawa, Hideki, additional, Nagahara, Akihito, additional, and Saito, Yutaka, additional

Published
2023
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25. Association between continuous cessation or reduction of drinking alcohol and improvement of multiple dysplastic lesions in patients with esophageal squamous cell carcinoma after endoscopic resection

Author

Hori, Keisuke, primary, Katada, Chikatoshi, additional, Okada, Hiroyuki, additional, Katagiri, Atsushi, additional, Matsuo, Yasumasa, additional, Yokoyama, Tetsuji, additional, Yano, Tomonori, additional, Suzuki, Haruhisa, additional, Shimizu, Yuichi, additional, Furue, Yasuaki, additional, Nakanishi, Hiroyoshi, additional, Koike, Tomoyuki, additional, Takizawa, Kohei, additional, Hirao, Motohiro, additional, Yoshii, Takako, additional, Yamanouchi, Takenori, additional, Kawakubo, Hirofumi, additional, Kobayashi, Nozomu, additional, Shimoda, Tadakazu, additional, Ochiai, Atsushi, additional, Ishikawa, Hideki, additional, Yokoyama, Akira, additional, and Muto, Manabu, additional

Published
2023
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27. Endoscopist‐related factors affecting adenoma detection during colonoscopy: data from the J‐SCOUT study

Author

Kawamura, Takuji, primary, Sekiguchi, Masau, additional, Takamaru, Hiroyuki, additional, Mizuguchi, Yasuhiko, additional, Horiguchi, Go, additional, Toyoizumi, Hirobumi, additional, Kato, Masayuki, additional, Kobayashi, Kiyonori, additional, Sada, Miwa, additional, Oda, Yasushi, additional, Yokoyama, Akira, additional, Utsumi, Takahiro, additional, Tsuji, Yosuke, additional, Ohki, Daisuke, additional, Takeuchi, Yoji, additional, Shichijo, Satoki, additional, Ikematsu, Hiroaki, additional, Matsuda, Koji, additional, Teramukai, Satoshi, additional, Kobayashi, Nozomu, additional, Matsuda, Takahisa, additional, Saito, Yutaka, additional, and Tanaka, Kiyohito, additional

Published
2023
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28. The Influence of Age on the Outcomes of Traumatic Brain Injury: Findings from a Japanese Nationwide Survey (J-ASPECT Study-Traumatic Brain Injury)

Author

Takigami, Masayoshi, Kamiyama, Kenji, Houkin, Kiyohiro, Nishi, Shougo, Yoshimoto, Tetsuyuki, Kaneko, Sadao, Oka, Koji, Ooyama, Hiroshi, Kamada, Kyousuke, Makino, Kenichi, Tokumitsu, Naoki, Sako, Kazuhiro, Suzuki, Susumu, Suzuki, Nozomi, Izumi, Naoto, Nitta, Kazumi, Ootaki, Masahumi, Isobe, Masanori, Nishiya, Mikio, Yamazaki, Takaaki, Mabuchi, Syouji, Ogasawara, Kuniaki, Kubo, Naohiko, Shimizu, Yukihiko, Saito, Keiichi, Yamanome, Tatumi, Yoshino, Atsuo, Fujitsuka, Mitsuyuki, Takami, Masaaki, Ohtaka, Hirotoshi, Hirano, Teruyuki, Shiokawa, Yosiaki, Okada, Takaharu, Suzuki, Ichiro, Kohno, Michihiro, Haraoka, Jou, Arai, Yoshinori, Kawamura, Noriyoshi, Isoshima, Akira, Yasue, Masaharu, Takayoshi Kobayashi, Mitsuhiko Hokari, Kawai, Kensuke, Maehara, Taketoshi, Arai, Hajime, Noguchi, Makoto, Hoshino, Haruhiko, Hiyama, Hirofumi, Yoshida, Kensaku, Utsugi, Osamu, Takeda, Yasuaki, Tamaki, Kouichi, Karasudani, Hirohide, Urabe, Takao, Kobayashi, Shiro, Nakamura, Michio, Koguchi, Yorio, Ono, Junichi, Suda, Sumio, Hadeishi, Hiromu, Fukutake, Toshio, Wakui, Kenji, Tanno, Hirokazu, Ishige, Naoki, Ohasi, Takashi, Sakai, Hideki, Nishimura, Yasuaki, Watanabe, Takayuki, Matsumoto, Takashi, Koketsu, Naoki, Hirose, Yuichi, Doyu, Manabu, Hasegawa, Toshinori, Kuwayama, Naoto, Terao, Shinichi, Mizutani, Nobuhiko, Suzaki, Noriyuki, Okuda, Satoshi, Yasui, Keizo, Seki, Yukio, Hasegawa, Yasuhiro, Ikeda, Akira, Takeuchi, Youtarou, Ohara, Sigeki, Araki, Yoshio, Wakabayashi, Toshihiko, Tanaka, Hisashi, Yoshimoto, Junpei, Sugiura, Makoto, Koichiro, Ogura, Kobayashi, Nozomu, Yamada, Tomonori, Kato, Amami, Toshiho, Ohtsuki, Wakayama, Akatsuki, Takahashi, Jun, Kataoka, Hiroharu, Yoshimine, Toshiki, Nakajima, Yoshikazu, Gi, Hidehuku, Uranishi, Ryunosuke, Nakamura, Yusaku, Yamanaka, Kazunori, Ohmori, Kazumi, Matsumoto, Hiroyuki, Oiwa, Yoshitugu, Uemura, Yosihiko, Fujiwara, Hiroaki, Iwai, Yoshiyasu, Morikawa, Masashi, Tane, Kazuyuki, Hashikawa, Kazuo, Fujinaka, Toshiyuki, Yoneda, Shunichi, Yamashita, Kohsuke, Kitano, Masahiko, Tominaga, Shinsuke, Nakamura, Kazuhito, Kono, Katsuhiko, Ohata, Kenji, Taniguchi, Hirokatsu, Hazama, Takanori, Kuroiwa, Toshihiko, Tamura, Yoji, Maeno, Kazusige, Arai, Motohiro, Iwase, Masaaki, Hashimoto, Kenji, Yamada, Keisuke, Turuno, Takashi, Ichinose, Tsutomu, Kurokawa, Shinichiro, Matsuyama, Takeshi, Fujita, Toshiaki, Yuguchi, Takamichi, Teramoto, Yoshihumi, Kakita, Hiroto, Matsuo, Takayuki, Izumo, Tsuyoshi, Ryu, Nobutoshi, Naoki Kitagawa, Wataru Haraguchi, Kaminogo, Makio, Sakamoto, Seisaburo, Tokunaga, Yosiharu, Urasaki, Ei-Ichirou, Kuratsu, Junichi, Takada, Akira, Terasaki, Tadashi, Hisami Oosima, Isao Fuwa, Yamashiro, Shigeo, Hiromasa Tsuiki, Makoto Yoshikawa, Koga, Kazunari, Egami, Hiroshi, Kawamura, Tadao, Mitsuo, Kunihiko, Masaki Morisige, Takamitu Hikawa, Takeda, Yuu, Yamaguchi, Yutaka, Shunro Uchinokura, Shiro Miyata, Goya, Tomokazu, Takeshima, Hideo, Yatsushiro, Kazutaka, Ohta, Hajime, Nagadou, Tatsui, Hirahara, Kazuho, Obara, Souichi, Seto, Hiroshi, Moroki, Koiti, Arita, Kazunori, Ishiuchi, Shogo, Uchihara, Toshimitsu, Mekaru, Susumu, Nagamine, Tomoaki, Jin Momoji, Naoki Tomiyama, Atusi Kimoto, Kouzi Idomari, Kadekaru, Tsutomu, Syamoto, Hirosi, Sasaki, Osamu, Minagawa, Makoto, Takahashi, Hideaki, Hiroyuki Arai, Kiyoshi Onda, Takeuchi, Shigekazu, Abe, Hiroshi, Fukuda, Osamu, Kouno, Mitsuo, Tamura, Tetsuro, Michiya Kubo, Yukio Horie, Hondo, Hiroaki, Takada, Hisashi, Masuoka, Toru, Shirasaki, Naoki, Nitta, Hisashi, Yasuo Katsuki, Makoto Kimura, Hisato Minamide, Yutaka Hayashi, Munemoto, Shigeru, Ikeda, Kiyonobu, Yutaka Hayashi, Mitsutoshi Nakada, Sato, Syuji, Hatano, Taketo, Yamamura, Osamu, Kabuto, Masanori, Jyunya Hayashi, Takahiro Sakuma, Kinouchi, Hiroyuki, Koizumi, Hidehito, Imae, Syougo, Fujita, Manabu, Suga, Masakazu, Kanehisa Kohno, Shinji Iwata, Zenke, Kiichiro, Fujisawa, Mutsuo, Mizobuchi, Hikaru, Hayashi, Satoru, Morimoto, Masanori, Ueba, Tetsuya, Nishimura, Hiroyuki, Ikawa, Naoki, Matsumoto, Yuzo, Kannuki, Seiji, Kagawa, Masahiro, Hayashi, Naoki, Atsushi Shindo, Takashi Tamiya, Yoshino, Kimihiro, Masaoka, Tetsuya, Nakahara, Ichiro, Satoshi Suzuki, Akira Nakamizo, Okamoto, Yuji, Takahashi, Haruki, Iihara, Koji, Hirakawa, Katsuyuki, Nagata, Shinji, Ookura, Akio, Yoshiro Kaneko, Hidenori Yoshida, Nakane, Hiroshi, Inoue, Isao, Hitotsumatsu, Tsutomu, Kouichi Kuramoto, Terukazu Kuramoto, Hiromichi Ooishi, Yoshihisa Matumoto, Masani Nonaka, Tooru Inoue, Morioka, Motohiro, Shuji Sakata, Hiroshi Sugimori, Takashima, Hiroshi, Ishihara, Shin-Ichiro, Suzuyama, Kenji, Miyazono, Masayuki, Itaro Hattori, Masafumi Morimoto, Ozaki, Satoshi, Hirota, Nobuo, Yasuhiko Mochimatsu, Yasunori Takemoto, Takagi, Makoto, Kenji Nakayama, Isao Yamamoto, Hiroshi Tanaka, Yoshinori Uchida, Sakata, Katsumi, Nobutaka, Kawahara, Nomura, Motohiro, Ozawa, Hitoshi, Tsumura, Kotaro, Michiyuki Maruyama, Makoto Inaba, Mori, Tatsuro, Mori, Takahisa, Sugitani, Masato, Tanaka, Yuichiro, Yamada, Masaru, Matsumae, Mitsunori, Onitsuka, Keiichirou, Tatsuya Takahashi, Kosuke Miyahara, Endou, Sumio, Takahashi, Hidekazu, Kaidu, Hiroyuki, Chikashi Maruki, Akira Tsunoda, Fujimaki, Takamitsu, Ooigawa, Hidetoshi, Masatsugu Uchida, Masahiko Tanaka, Kouiti Katoh, Hiroshi Wanihuti, Hyodo, Akio, Asakura, Ken, Nakajima, Shigeyoshi, Kanzawa, Takao, Kurihara, Hideyuki, Ohmori, Sigehiro, Hiroshi Kusunoki, Mitsugi Yoshinao, Magarisawa, Satoshi, Okabe, Shinichi, Kujiraoka, Yuuji, Tsuruoka, Shin, Takeshita, Mikihiko, Akira Matsumura, Tetsuya Yamamoto, Uemura, Kazuya, Tabata, Hitoshi, Sonobe, Makoto, Ryoji Yoshida, Masashi Nakatsukasa, Shimoeda, Norifumi, Kunimine, Hideo, Ishihara, Masayuki, Murai, Nozomu, Murakami, Nobukuni, Kidooka, Minoru, Iwamoto, Yoshihiro, Tenjin, Hiroshi, Masahiko Takamasu, Kouji Shiga, Mori, Nobuhito, Kose, Shigeru, Kohmura, Eiji, Matsumoto, Keigo, Sakaki, Takayuki, Miyake, Hiroji, Mabuchi, Eiichiro, Yokota, Masayuki, Yosihiro Kuga, Hideyuki Ohnishi, Kimura, Mitsuru, Masaaki Saiki, Osamu Narumi, Nakajima, Norio, Asahi, Minoru, Koyama, Junji, Noda, Shinya, Iida, Junichi, Fujita, Toyohisa, Nakase, Hiroyuki, Toru Hoshida, Hidehiro Hirabayashi, Fujimoto, Takayoshi, Nakao, Naoyuki, Tanaka, Yoshiyuki, Ozaki, Fuminori, Nakamura, Yoshinari, Miki, Kazuhito, Watanabe, Takashi, Hasegawa, Seiko, Konno, Hiromu, Takemura, Atsuhito, Okubo, Atsuya, Saito, Hitoshi, Taizen Nakase, Tatsuya Ishikawa, Toshio Sasajima, Hiroaki Shimizu, Sasou, Masayuki, Watanabe, Yoichi, Kiyoshi Saito, Taku Sato, Masahiro Satoh, Satoshi Taira, Koizumi, Takayuki, Shoji Mashiyama, Yasuhiro Suzuki, Oikawa, Tomoyoshi, Sonoda, Yukihiko, Shinjiro Saito, Rei Kondo, Shinoda, Atsuo, Kamatsuka, Eiichiro, So, Keiten, Kinjo, Toshihiko, Kennji Itou, Tooru Sasaki, Hiroaki Shimizu, Hidenori Endo, Karibe, Hirosi, Takahashi, Kou, Nakajima, Masayuki, Watanabe, Kazuyoshi, Takayama, Motohiro, Komuro, Taro, Fumio Suzuki, Hisao Hirai, Suzuki, Hidenori, Murata, Hiroto, Miya, Fumitaka, Kanamaru, Kenji, Tamura, Akira, Harada, Kiyoshi, Fukazawa, Seiji, Takehara, Seiya, Watanabe, Yoshihiko, Nakayama, Teiji, Hiroshi Nagura, Haruhiko Sato, Chiharu Tanoi, Shinji Amano, Kuroda, Katsuhiro, Morooka, Satoru, Masashi Kitagawa, Takafumi Wataya, Koide, Kazuo, Tanigawara, Tetsuya, Iwama, Toru, Ito, Junki, Noda, Shinji, Kouno, Kazuyuki, Kitazawa, Kazuo, Toshiki Takemae, Yoshikazu Kusano, Hokama, Masanobu, Yoshihisa Nishiyama, Hiroki Sato, Seguchi, Tatsuya, Yoshihiko Inui, Sumio Kobayashi, Oohigashi, Youji, Muraoka, Shinsuke, Miyatake, Masaki, Nakagawa Shinichi, Kensuke Hayashida, Inoue, Atsushi, Sakai, Keiichi, Yamaguchi, Shuhei, Fusao Ikawa, Tatsuya Mizoue, Hideki Irie, Gen Ishida, Kagawa, Takato, Namba, Yoichiro, Nakashima, Hiroyuki, Koji Abe, Isao Date, Uno, Masaaki, Sen Yamagata, Masaki Chin, Soitiro Takao, Hidemiti Sasayama, Kouji Muneda, Hideyuki Yoshida, Watanebe, Akira, Katou, Syouichi, Hamada, Yasuhiro, Suzuki, Michiyasu, Nishizaki, Takafumi, Yamashita, Katsuhiro, Ryuji Nakamura, Takaharu Nakamura, Wakabayashi, Shinichi, Okazaki, Takahito, Kurisu, Kaoru, Matsumoto, Masayasu, Katsuzo Kiya, Atsushi Tominaga, Syuichi Oki, Masaaki Shibukawa, Nakahara, Toshinori, Okita, Shinji, Torii, Tuyosi, Kenjirou Fujiwara, Minoru Nakagawa, Syuuhei Nishimura, Takashi Matsuoka, Naoyuki Isobe, Osamu Hamasaki, Shinji Nagahiro, Junichiro Satomi, Agawa, Masahito, Oka, Hirofumi, Yoshimura, Kunikazu, Kato, Tsutomu, Satoshi Minoshima, Nobuaki Kobayasi, Mikuni, Nobuhiro, Tanikawa, Rokuya, Sasaki, Jyunkou, Otawara, Yasunari, Tominaga, Teiji, Sasaki, Tatsuya, Takemura, Sunao, Kawakami, Masahisa, Ihara, Satoshi, Shibata, Yasushi, Saegusa, Takashi, Iuchi, Toshihiko, Ito, Chiaki, Okuda, Osamu, Yoshida, Kazunari, Masateru Katayama, Sadao Suga, Akihiro, Oikawa, Miura, Naohisa, Ota, Takahiro, Kumabe, Toshihiro, Suzuki, Sachio, Kumagai, Takashi, Nishimaki, Keiichi, Hongo, Kazuhiro, Shigeta, Hiroaki, Hattori, Kazuyoshi, Uozumi, Yoichi, Nakahara, Norimoto, Hashimoto, Nobukazu, Shu Imai, Shinichi Shirakami, Okumura, Yoshinari, Kazuhiro Yokoyama, Ryo Tamaki, Miyamoto, Susumu, Yamamoto, Kazuo, Ichioka, Tsugumichi, Inoue, Tsuyoshi, Kinoshita, Manabu, Saitoh, Minoru, Aihara, Hideo, Miyake, Hajimu, Tukasa Nishiura, Kotaro Ogihara, Nishino, Shigeki, Miyoshi, Yasuyuki, Arisawa, Tadashi, Shoji Tsuchimoto, Shigeru Daido, Kinoshita, Kimihisa, Keisuke Migita, Kiyoshi Yuki, Akatsuka, Keiichi, Fujisawa, Hirosuke, Shono, Tadahisa, Tsugu, Hitoshi, Hayashi, Shuji, Toshio Matsushima, Tatsuya Abe, Nakashima, Susumu, Tuji, Takehisa, Kaga, Akihiko, Kanemaru, Reizou, Takasaki, Koji, Imamura, Junichi, Noha, Masahiro, Watanabe, Saburo, Sakai, Nobuyuki, Hiroaki Minami, Yasuhisa Yoshida, Okumura, Tomoyoshi, Nishimura, Shinjitsu, Numazawa, Shinichi, Masanori Tsutsumi, Kiyoshi Kazekawa, Fukuyama, Kouzou, Fujimoto, Yasuhiro, Yamagami, Keitaro, Kurogi, Ryota, Kurogi, Ai, Nishimura, Kunihiro, Onozuka, Daisuke, Ren, Nice, Kada, Akiko, Nishimura, Ataru, Arimura, Koichi, Ido, Keisuke, Mizoguchi, Masahiro, Sakamoto, Tetsuya, Kayama, Takamasa, and Hagihara, Akihito

Published
2019
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29. Association between macrocytosis and metachronous squamous cell carcinoma of the esophagus after endoscopic resection in men with early esophageal squamous cell carcinoma

Author

Katada, Chikatoshi, Yokoyama, Tetsuji, Yano, Tomonori, Oda, Ichiro, Shimizu, Yuichi, Doyama, Hisashi, Koike, Tomoyuki, Takizawa, Kohei, Hirao, Motohiro, Okada, Hiroyuki, Yoshii, Takako, Kubota, Yutaro, Yamanouchi, Takenori, Tsuda, Takashi, Omori, Tai, Kobayashi, Nozomu, Suzuki, Haruhisa, Tanabe, Satoshi, Hori, Keisuke, Nakayama, Norisuke, Kawakubo, Hirofumi, Kakushima, Naomi, Matsuo, Yasumasa, Ishikawa, Hideki, Yokoyama, Akira, and Muto, Manabu

Published
2020
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31. Efficacy of Endoscopic Resection and Selective Chemoradiotherapy for Stage I Esophageal Squamous Cell Carcinoma

Author

Minashi, Keiko, Nihei, Keiji, Mizusawa, Junki, Takizawa, Kohei, Yano, Tomonori, Ezoe, Yasumasa, Tsuchida, Tomohiro, Ono, Hiroyuki, Iizuka, Toshiro, Hanaoka, Noboru, Oda, Ichiro, Morita, Yoshinori, Tajika, Masahiro, Fujiwara, Junko, Yamamoto, Yoshinobu, Katada, Chikatoshi, Hori, Shinichiro, Doyama, Hisashi, Oyama, Tsuneo, Nebiki, Hiroko, Amagai, Kenji, Kubota, Yutaro, Nishimura, Ken, Kobayashi, Nozomu, Suzuki, Takuto, Hirasawa, Kingo, Takeuchi, Toshihisa, Fukuda, Haruhiko, and Muto, Manabu

Published
2019
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33. Endoscopist‐related factors affecting adenoma detection during colonoscopy: Data from the J‐SCOUT study.

Author

Kawamura, Takuji, Sekiguchi, Masau, Takamaru, Hiroyuki, Mizuguchi, Yasuhiko, Horiguchi, Go, Toyoizumi, Hirobumi, Kato, Masayuki, Kobayashi, Kiyonori, Sada, Miwa, Oda, Yasushi, Yokoyama, Akira, Utsumi, Takahiro, Tsuji, Yosuke, Ohki, Daisuke, Takeuchi, Yoji, Shichijo, Satoki, Ikematsu, Hiroaki, Matsuda, Koji, Teramukai, Satoshi, and Kobayashi, Nozomu

Subjects
ADENOMA, COLONOSCOPY, DATABASES, ODDS ratio, CONFIDENCE intervals
Abstract

Objectives: Colonoscopy withdrawal times are associated with the adenoma detection rate (ADR). However, the relationship between ADR and cecal insertion time has been inadequately characterized. We aimed to evaluate endoscopist‐related factors involved in the ADR, including the average individual colonoscopy insertion and withdrawal times. Methods: This observational study used a colonoscopy database with pathology data from routine clinical practice in Japanese institutions. The odds ratios (OR) of endoscopist‐related factors related to ADRs were examined using a generalized linear mixed model. Results: Of the 186,293 colonoscopies performed during the study period, 47,705 colonoscopies by 189 endoscopists in four hospitals were analyzed for ADR. The overall ADR was 38.3% (95% confidence interval [CI] 37.8, 38.7). Compared to endoscopists with mean cecal insertion times of <5 min, the OR of ADR for those with mean cecal insertion times of 5–9, 10–14, and ≥15 min were 0.84 (95% CI 0.71, 0.99), 0.68 (95% CI 0.52, 0.90), and 0.45 (95% CI 0.25, 0.78), respectively. Compared to endoscopists with mean withdrawal times of <6 min, the OR of ADR for those with mean withdrawal times of 6–9, 10–14, and ≥15 min were 1.38 (95% CI 1.03, 1.85), 1.48 (95% CI 1.09, 2.02), and 1.68 (95% CI 1.04, 2.61), respectively. There were no significant differences in ADRs by endoscopist specialty, gender, or the total number of examinations performed. Conclusion: Individual mean colonoscopy insertion time was associated with ADR and might be considered as a colonoscopy quality indicator as well as withdrawal time. [ABSTRACT FROM AUTHOR]

Published
2024
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34. Endoscopic Removal of Premalignant Lesions Reduces Long-Term Colorectal Cancer Risk: Results from the Japan Polyp Study

Author

Sano, Yasushi, primary, Hotta, Kinichi, additional, Matsuda, Takahisa, additional, Murakami, Yoshitaka, additional, Fujii, Takahiro, additional, Kudo, Shin-ei, additional, Oda, Yasushi, additional, Ishikawa, Hideki, additional, Saito, Yutaka, additional, Kobayashi, Nozomu, additional, Sekiguchi, Masau, additional, Ikematsu, Hiroaki, additional, Katagiri, Atsushi, additional, Konishi, Kazuo, additional, Takeuchi, Yoji, additional, Iishi, Hiroyasu, additional, Igarashi, Masahiro, additional, Kobayashi, Kiyonori, additional, Sada, Miwa, additional, Osera, Shozo, additional, Shinohara, Tomoaki, additional, Yamaguchi, Yuichiro, additional, Hasuda, Kiwamu, additional, Morishima, Toshitaka, additional, Miyashiro, Isao, additional, Shimoda, Tadakazu, additional, Taniguchi, Hirokazu, additional, Fujimori, Takahiro, additional, Ajioka, Yoichi, additional, and Yoshida, Shigeaki, additional

Published
2023
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35. Intensive endoscopic resection for downstaging of polyp burden in patients with familial adenomatous polyposis (J-FAPP Study III): a multicenter prospective interventional study

Author

Ishikawa, Hideki, Yamada, Masayoshi, Sato, Yasushi, Tanaka, Shinji, Chino, Akiko, Tajika, Masahiro, Doyama, Hisashi, Takayama, Tetsuji, Ohda, Yoshio, Horimatsu, Takahiro, Sano, Yasushi, Tanakaya, Kohji, Ikematsu, Hiroaki, Saida, Yoshihisa, Ishida, Hideyuki, Takeuchi, Yoji, Kashida, Hiroshi, Kiriyama, Shinsuke, Hori, Shinichiro, Lee, Kyowon, Tashiro, Jun, Kobayashi, Nozomu, Nakajima, Takeshi, Suzuki, Sadao, and Mutoh, Michihiro

Subjects
Gastroenterology
Abstract

Background Total colectomy is the standard treatment for familial adenomatous polyposis (FAP). Recently, an increasing number of young patients with FAP have requested the postponement of surgery or have refused to undergo surgery. We aimed to evaluate the effectiveness of intensive endoscopic removal for downstaging of polyp burden (IDP) in FAP. Method A single-arm intervention study was conducted at 22 facilities. Participants were patients with FAP, aged ≥ 16 years, who had not undergone colectomy or who had undergone colectomy but had ≥ 10 cm of large intestine remaining. For IDP, colorectal polyps of ≥ 10 mm were removed, followed by polyps of ≥ 5 mm. The primary end point was the presence/absence of colectomy during a 5-year intervention period. Results 222 patients were eligible, of whom 166 had not undergone colectomy, 46 had undergone subtotal colectomy with ileorectal anastomosis, and 10 had undergone partial resection of the large intestine. During the intervention period, five patients (2.3 %, 95 % confidence interval [CI] 0.74 %–5.18 %) underwent colectomy, and three patients died. Completion of the 5-year intervention period without colectomy was confirmed in 150 /166 patients who had not undergone colectomy (90.4 %, 95 %CI 84.8 %–94.4 %) and in 47 /56 patients who had previously undergone colectomy (83.9 %, 95 %CI 71.7 %–92.4 %). Conclusion IDP in patients with mild-to-moderate FAP could have the potential to be a useful means of preventing colorectal cancer without implementing colectomy. However, if the IDP protocol was proposed during a much longer term, it may not preclude the possibility that a large proportion of colectomies may still need to be performed.

Published
2022

42. Cost‐effectiveness analysis of computer‐aided detection systems for colonoscopy in Japan.

Author

Sekiguchi, Masau, Igarashi, Ataru, Toyoshima, Naoya, Takamaru, Hiroyuki, Yamada, Masayoshi, Esaki, Minoru, Kobayashi, Nozomu, and Saito, Yutaka

Subjects
COMPUTER-aided diagnosis, ADENOMATOUS polyps, COLONOSCOPY, COST effectiveness, MEDICAL screening, COLORECTAL cancer
Abstract

Objectives: The usefulness of computer‐aided detection systems (CADe) for colonoscopy has been increasingly reported. In many countries, however, data on the cost‐effectiveness of their use are lacking; consequently, CADe for colonoscopy has not been covered by health insurance. We aimed to evaluate the cost‐effectiveness of colonoscopy using CADe in Japan. Methods: We conducted a simulation model analysis using Japanese data to examine the cost‐effectiveness of colonoscopy with and without CADe for a population aged 40–74 years who received colorectal cancer (CRC) screening with a fecal immunochemical test (FIT). The rates of receiving FIT screening and colonoscopy following a positive FIT were set as 40% and 70%, respectively. The sensitivities of FIT for advanced adenomas and CRC Dukes' A–D were 26.5% and 52.8–78.3%, respectively. CADe colonoscopy was judged to be cost‐effective when its incremental cost‐effectiveness ratio (ICER) was below JPY 5,000,000 per quality‐adjusted life‐years (QALYs) gained. Results: Compared to conventional colonoscopy, CADe colonoscopy showed a higher QALY (20.4098 vs. 20.4088) and lower CRC incidence (2373 vs. 2415 per 100,000) and mortality (561 vs. 569 per 100,000). When the CADe cost was set at JPY 1000–6000, the ICER per QALY gained for CADe colonoscopy was lower than JPY 5,000,000 (JPY 796,328–4,971,274). The CADe cost threshold at which the ICER for CADe colonoscopy exceeded JPY 5,000,000 was JPY 6040. Conclusions: Computer‐aided detection systems for colonoscopy has the potential to be cost‐effective when the CADe cost is up to JPY 6000. These results suggest that the insurance reimbursement of CADe for colonoscopy is reasonable. [ABSTRACT FROM AUTHOR]

Published
2023
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43. Alcohol Consumption and Multiple Dysplastic Lesions Increase Risk of Squamous Cell Carcinoma in the Esophagus, Head, and Neck

Author

Katada, Chikatoshi, Yokoyama, Tetsuji, Yano, Tomonori, Kaneko, Kazuhiro, Oda, Ichiro, Shimizu, Yuichi, Doyama, Hisashi, Koike, Tomoyuki, Takizawa, Kohei, Hirao, Motohiro, Okada, Hiroyuki, Yoshii, Takako, Konishi, Kazuo, Yamanouchi, Takenori, Tsuda, Takashi, Omori, Tai, Kobayashi, Nozomu, Shimoda, Tadakazu, Ochiai, Atsushi, Amanuma, Yusuke, Ohashi, Shinya, Matsuda, Tomonari, Ishikawa, Hideki, Yokoyama, Akira, and Muto, Manabu

Published
2016
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44. Final Analysis of Diagnostic Endoscopic Resection Followed by Selective Chemoradiotherapy for Stage I Esophageal Cancer: JCOG0508

Author

Nihei, Keiji, primary, Minashi, Keiko, additional, Yano, Tomonori, additional, Shimoda, Tadakazu, additional, Fukuda, Haruhiko, additional, Muto, Manabu, additional, Mizuaswa, Junki, additional, Takizawa, Kohei, additional, Aoyama, Ikuo, additional, Ishiyama, Akiyoshi, additional, Kawata, Noboru, additional, Kikuchi, Daisuke, additional, Hanaoka, Noboru, additional, Oda, Ichiro, additional, Morita, Yoshinori, additional, Tajika, Masahiro, additional, Fujiwara, Junko, additional, Yamamoto, Yoshinobu, additional, Katada, Chikatoshi, additional, Hori, Shinichiro, additional, Doyama, Hisashi, additional, Oyama, Tsuneo, additional, Nebiki, Hiroko, additional, Amagai, Kenji, additional, Kubota, Yutaro, additional, Inokuchi, Yasuhiro, additional, Kobayashi, Nozomu, additional, Suzuki, Takuto, additional, Hirasawa, Kingo, additional, Takeuchi, Toshihisa, additional, and Kadota, Tomohiro, additional

Published
2023
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45. Reply

Author

Ken, Ohata, primary, Kobayashi, Nozomu, additional, and Saito, Yutaka, additional

Published
2023
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46. Long-term Survival After Endoscopic Resection For Gastric Cancer: Real-world Evidence From a Multicenter Prospective Cohort

Author

Suzuki, Haruhisa, primary, Ono, Hiroyuki, additional, Hirasawa, Toshiaki, additional, Takeuchi, Yoji, additional, Ishido, Kenji, additional, Hoteya, Shu, additional, Yano, Tomonori, additional, Tanaka, Shinji, additional, Toya, Yosuke, additional, Nakagawa, Masahiro, additional, Toyonaga, Takashi, additional, Takemura, Kenichi, additional, Hirasawa, Kingo, additional, Matsuda, Mitsuru, additional, Yamamoto, Hironori, additional, Tsuji, Yosuke, additional, Hashimoto, Satoru, additional, Yuki, Maeda, additional, Oyama, Tsuneo, additional, Takenaka, Ryuta, additional, Yamamoto, Yoshinobu, additional, Naito, Yuji, additional, Yamamoto, Katsumi, additional, Kobayashi, Nozomu, additional, Kawahara, Yoshiro, additional, Hirano, Masaaki, additional, Koizumi, Shigeto, additional, Hori, Shinichiro, additional, Tajika, Masahiro, additional, Hikichi, Takuto, additional, Yao, Kenshi, additional, Yokoi, Chizu, additional, Ohnita, Ken, additional, Hisanaga, Yasuhiro, additional, Sumiyoshi, Tetsuya, additional, Kitamura, Shinji, additional, Tanaka, Hisao, additional, Shimoda, Ryo, additional, Shimazu, Taichi, additional, Takizawa, Kohei, additional, Tanabe, Satoshi, additional, Kondo, Hitoshi, additional, Iishi, Hiroyasu, additional, Ninomiya, Motoki, additional, Oda, Ichiro, additional, Mashimo, Yumi, additional, Ishigooka, Masahiro, additional, Fukase, Kazutoshi, additional, and Mizuguchi, Yasuhiko, additional

Published
2023
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47. “Endoscopic” adenoma detection rate as a quality indicator of colonoscopy: First report from the J‐SCOUT study

Author

Kawamura, Takuji, primary, Sekiguchi, Masau, additional, Takamaru, Hiroyuki, additional, Mizuguchi, Yasuhiko, additional, Horiguchi, Go, additional, Kato, Masayuki, additional, Kobayashi, Kiyonori, additional, Sada, Miwa, additional, Oda, Yasushi, additional, Yokoyama, Akira, additional, Utsumi, Takahiro, additional, Tsuji, Yosuke, additional, Ohki, Daisuke, additional, Takeuchi, Yoji, additional, Shichijo, Satoki, additional, Ikematsu, Hiroaki, additional, Matsuda, Koji, additional, Teramukai, Satoshi, additional, Kobayashi, Nozomu, additional, Matsuda, Takahisa, additional, Saito, Yutaka, additional, and Tanaka, Kiyohito, additional

Published
2023
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49. Long-term Outcomes After Endoscopic Submucosal Dissection for Large Colorectal Epithelial Neoplasms: A Prospective, Multicenter, Cohort Trial From Japan

Author

Ohata, Ken, primary, Kobayashi, Nozomu, additional, Sakai, Eiji, additional, Takeuchi, Yoji, additional, Chino, Akiko, additional, Takamaru, Hiroyuki, additional, Kodashima, Shinya, additional, Hotta, Kinichi, additional, Harada, Keita, additional, Ikematsu, Hiroaki, additional, Uraoka, Toshio, additional, Murakami, Takashi, additional, Tsuji, Shigetsugu, additional, Abe, Takashi, additional, Katagiri, Atsushi, additional, Hori, Shinichiro, additional, Michida, Tomoki, additional, Suzuki, Takuto, additional, Fukuzawa, Masakatsu, additional, Kiriyama, Shinsuke, additional, Fukase, Kazutoshi, additional, Murakami, Yoshitaka, additional, Ishikawa, Hideki, additional, and Saito, Yutaka, additional

Published
2022
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