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137 results on '"Kobayashi, Nobutaka"'

1. A case of leiomyosarcoma originating from the azygos vein.

Author

Shimura, Masatoshi, Kobayashi, Nobutaka, and Miyazawa, Masahisa

Abstract

Leiomyosarcoma is a soft‐tissue sarcoma that accounts for less than 1% of all malignant tumors. Furthermore, leiomyosarcoma accounts for 6% of all soft tissue sarcomas, and leiomyosarcoma of azygos vein origin is extremely rare. In this report, we describe a case of leiomyosarcoma derived from an azygos vein that was completely resected. A 78‐year‐old male patient was incidentally found to have a mediastinal mass during a computed tomography (CT) scan performed for the evaluation of prostate cancer. Bronchoscopic needle biopsy revealed the mass to be a leiomyosarcoma. Preoperative contrast‐enhanced CT demonstrated a filling defect in the azygos vein, suggesting the tumor's origin from this structure. Video‐assisted thoracoscopic surgery (VATS) was performed to resect the mediastinal tumor. The tumor was found to have minimal adhesions to surrounding tissues and no evidence of local invasion, although findings suggested it originated from the azygos vein. Consequently, en bloc resection of the azygos vein was performed. Postoperative histopathological examination confirmed the diagnosis of leiomyosarcoma originating from the azygos vein, and complete resection was performed. [ABSTRACT FROM AUTHOR]

Published
2024
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4. A rare case of empyema caused by septic arthritis of the sternoclavicular joint, successfully treated with surgical drainage.

Author

Koike, Sachie, Miyazawa, Masahisa, and Kobayashi, Nobutaka

Subjects
STERNOCLAVICULAR joint, INFECTIOUS arthritis, EMPYEMA, MEDICAL drainage, JOINT infections, TREATMENT effectiveness, ABSCESSES
Abstract

Septic arthritis of the sternoclavicular joint is a rare joint infection, and it sometimes leads to a chest wall abscess or mediastinitis. We report a case of a 70-year-old man who was diagnosed with empyema caused by an anterior chest wall abscess extended from septic arthritis of the sternoclavicular joint. It is very rare that arthritis causes empyema combined with an anterior chest wall abscess, and this is the first report of such a case. The patient was successfully treated with surgical drainage. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Data from Hyaluronan Deficiency in Tumor Stroma Impairs Macrophage Trafficking and Tumor Neovascularization

Author

Kobayashi, Nobutaka, primary, Miyoshi, Seiji, primary, Mikami, Takahide, primary, Koyama, Hiroshi, primary, Kitazawa, Masato, primary, Takeoka, Michiko, primary, Sano, Kenji, primary, Amano, Jun, primary, Isogai, Zenzo, primary, Niida, Shumpei, primary, Oguri, Kayoko, primary, Okayama, Minoru, primary, McDonald, John A., primary, Kimata, Koji, primary, Taniguchi, Shun'ichiro, primary, and Itano, Naoki, primary

Published
2023
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9. Supplementary Figure 2 from Hyaluronan Deficiency in Tumor Stroma Impairs Macrophage Trafficking and Tumor Neovascularization

Author

Kobayashi, Nobutaka, primary, Miyoshi, Seiji, primary, Mikami, Takahide, primary, Koyama, Hiroshi, primary, Kitazawa, Masato, primary, Takeoka, Michiko, primary, Sano, Kenji, primary, Amano, Jun, primary, Isogai, Zenzo, primary, Niida, Shumpei, primary, Oguri, Kayoko, primary, Okayama, Minoru, primary, McDonald, John A., primary, Kimata, Koji, primary, Taniguchi, Shun'ichiro, primary, and Itano, Naoki, primary

Published
2023
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10. Supplementary Figure 3 from Hyaluronan Deficiency in Tumor Stroma Impairs Macrophage Trafficking and Tumor Neovascularization

Author

Kobayashi, Nobutaka, primary, Miyoshi, Seiji, primary, Mikami, Takahide, primary, Koyama, Hiroshi, primary, Kitazawa, Masato, primary, Takeoka, Michiko, primary, Sano, Kenji, primary, Amano, Jun, primary, Isogai, Zenzo, primary, Niida, Shumpei, primary, Oguri, Kayoko, primary, Okayama, Minoru, primary, McDonald, John A., primary, Kimata, Koji, primary, Taniguchi, Shun'ichiro, primary, and Itano, Naoki, primary

Published
2023
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11. Supplementary Methods, Figure Legends 1-3 from Hyaluronan Deficiency in Tumor Stroma Impairs Macrophage Trafficking and Tumor Neovascularization

Author

Kobayashi, Nobutaka, primary, Miyoshi, Seiji, primary, Mikami, Takahide, primary, Koyama, Hiroshi, primary, Kitazawa, Masato, primary, Takeoka, Michiko, primary, Sano, Kenji, primary, Amano, Jun, primary, Isogai, Zenzo, primary, Niida, Shumpei, primary, Oguri, Kayoko, primary, Okayama, Minoru, primary, McDonald, John A., primary, Kimata, Koji, primary, Taniguchi, Shun'ichiro, primary, and Itano, Naoki, primary

Published
2023
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12. Supplementary Figure 1 from Hyaluronan Deficiency in Tumor Stroma Impairs Macrophage Trafficking and Tumor Neovascularization

Author

Kobayashi, Nobutaka, primary, Miyoshi, Seiji, primary, Mikami, Takahide, primary, Koyama, Hiroshi, primary, Kitazawa, Masato, primary, Takeoka, Michiko, primary, Sano, Kenji, primary, Amano, Jun, primary, Isogai, Zenzo, primary, Niida, Shumpei, primary, Oguri, Kayoko, primary, Okayama, Minoru, primary, McDonald, John A., primary, Kimata, Koji, primary, Taniguchi, Shun'ichiro, primary, and Itano, Naoki, primary

Published
2023
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31. Pulmonary metastasis with coexisting pulmonary mucosa‐associated lymphoid tissue (MALT) lymphoma 20 years after endometrioid adenocarcinoma surgery: A case report.

Author

Nakamura, Daisuke, Kobayashi, Nobutaka, Miyazawa, Masahisa, Miura, Kentaro, and Satomi, Hidetoshi

Subjects
*ADENOCARCINOMA, *B cell lymphoma, *CHEST X rays, *COMPUTED tomography, *LUNG tumors, *METASTASIS, *ENDOMETRIAL tumors
Abstract

Late pulmonary metastasis from endometrioid adenocarcinoma (EA) is rare, and occurrence after >20 years is extremely rare. Here, we report a case of pulmonary metastasis with coexisting pulmonary mucosa‐associated lymphoid tissue (MALT) lymphoma that occurred 20 years after surgery for EA. A 60‐year‐old Japanese woman had previously undergone surgery for primary EA, and 20 years later presented with an abnormality that was detected on chest radiography. Chest computed tomography (CT) revealed two nodules in the right lower lung lobe, which were suspected to be primary lung cancer. Wedge resection was performed, and the intraoperative pathological diagnosis was that of adenocarcinoma with MALT lymphoma; this prompted additional right lower lobectomy. The final pathological diagnosis was pulmonary metastasis from EA with coexisting MALT lymphoma. This is probably the first report on late pulmonary metastasis coexisting with MALT lymphoma 20 years after surgery for EA. Surgeons should be aware of the possibility of late pulmonary recurrence of EA after more than 20 years and should consider aggressive resection. Key points: Significant findings of the study: Although extremely rare, pulmonary metastasis can occur more than 20 years after surgery for endometrioid adenocarcinoma. Furthermore, pulmonary metastasis from endometrioid adenocarcinoma may coexist with mucosa‐associated lymphoid tissue lymphoma. What this study adds: Endometrioid adenocarcinoma requires long‐term postoperative follow‐up to detect recurrence, even in early‐stage cases. Video‐assisted thoracoscopic surgery (VATS) is useful for resecting pulmonary metastasis from endometrioid adenocarcinoma. [ABSTRACT FROM AUTHOR]

Published
2021
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37. Significance of Tumor-Associated Stroma in Promotion of Intratumoral Lymphangiogenesis : Pivotal Role of a Hyaluronan-Rich Tumor Microenvironment

Author

Koyama, Hiroshi, Kobayashi, Nobutaka, Harada, Michihiko, Takeoka, Michiko, Kawai, Yoshiko, Sano, Kenji, Fujimori, Minoru, Amano, Jun, Ohhashi, Toshio, Kannagi, Reiji, Kimata, Koji, Taniguchi, Shun’ichiro, and Itano, Naoki

Subjects
Mice, Transgenic, Immunohistochemistry, Models, Biological, Gene Expression Regulation, Neoplastic, Disease Models, Animal, Mice, Cell Movement, Neoplasms, Disease Progression, Animals, Humans, Endothelium, Vascular, Hyaluronic Acid, Lymphangiogenesis, Regular Articles, Lymphatic Vessels
Abstract

Stromal cells, together with extracellular matrix components, provide a tumor microenvironment that is pivotal for cancer cell growth and progression. In our previous study using a conditional transgenic mouse model of breast cancer, the overproduction of hyaluronan, a major extracellular constituent, accelerated tumor angiogenesis through stromal cell recruitment. This finding led us to investigate the role of hyaluronan in the lymphatic vessel system. Here, we have found that microenvironmental hyaluronan promoted tumor lymphangiogenesis concurrently with the formation of stromal structures. Additionally, lymphatic vessels frequently penetrated and accumulated into stromal compartments, and up-regulation of vascular endothelial growth factor-C and -D was detected at tumor-stromal interfaces. To assess the contribution of stromal cells to lymphangiogenesis in vivo, we established tumor-associated fibroblasts from hyaluronan-overproducing mammary tumors and implanted them together with carcinoma cells from control tumors or MCF-7 human breast carcinoma cells in nude mice. Carcinoma cells grew rapidly in association with marked stromal reactions and lymphangiogenesis. Without the stromal cells, however, the tumors developed slowly with less stroma and lymphatic vessels. These findings underline the significance of tumor-associated stroma in the promotion of intratumoral lymphangiogenesis and suggest a pivotal role for the hyaluronan-rich tumor microenvironment.

Published
2008

38. State Estimation for HAYABUSA2 Reentry Capsule with On-Board Gyro Sensor

Author

Kobayashi, Nobutaka, Ueno, Seiya, Yoshihara, Keisuke, and Yamada, Tetsuya

Abstract

平成23年度宇宙航行の力学シンポジウム（2011年12月19日-20日. 宇宙航空研究開発機構宇宙科学研究所）, 相模原市, 神奈川県, Symposium on Flight Mechanics and Astrodynamics 2011 (December 19-20, 2011. Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)(ISAS)), Sagamihara, Kanagawa Japan, 資料番号: SA6000006021

Published
2012

45. Hyaluronan Deficiency in Tumor Stroma Impairs Macrophage Trafficking and Tumor Neovascularization

Author

Kobayashi, Nobutaka, primary, Miyoshi, Seiji, additional, Mikami, Takahide, additional, Koyama, Hiroshi, additional, Kitazawa, Masato, additional, Takeoka, Michiko, additional, Sano, Kenji, additional, Amano, Jun, additional, Isogai, Zenzo, additional, Niida, Shumpei, additional, Oguri, Kayoko, additional, Okayama, Minoru, additional, McDonald, John A., additional, Kimata, Koji, additional, Taniguchi, Shun'ichiro, additional, and Itano, Naoki, additional

Published
2010
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50. Significance of Tumor-Associated Stroma in Promotion of Intratumoral Lymphangiogenesis

Author

Koyama, Hiroshi, primary, Kobayashi, Nobutaka, additional, Harada, Michihiko, additional, Takeoka, Michiko, additional, Kawai, Yoshiko, additional, Sano, Kenji, additional, Fujimori, Minoru, additional, Amano, Jun, additional, Ohhashi, Toshio, additional, Kannagi, Reiji, additional, Kimata, Koji, additional, Taniguchi, Shun'ichiro, additional, and Itano, Naoki, additional

Published
2008
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