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3. Performance evaluation of electron multiplier tubes as a high-intensity muon beam monitor of accelerator neutrino experiments

Author

Honjo, Takashi, Ashida, Yosuke, Auersperg-Castell, Oderich F., Friend, Megan, Heitkamp, Ian, Ichikawa, Atsuko K., Ishitsuka, Masaki, Izumi, Nao, Kasama, Sohei, Kashiwagi, Shigeru, Kawamura, Yuma, Kikawa, Tatsuya, Kobata, Takuya, Matsubara, Tsunayuki, Miyabe, Manabu, Nakamura, Kiseki D., Nakamura, Hina, Sato, Yukine, Sakashita, Ken, Seiya, Yoshihiro, Takifuji, Kouchi, Tokiyasu, Atsushi, Yamamoto, Tatsuya, Yamamoto, Kazuhiro, and Yasutome, Kenji

Subjects
Physics - Instrumentation and Detectors
Abstract

Upgrade work towards increasing the beam intensity of the neutrino beamline at J- PARC is underway. Monitoring tertiary muon beams is essential for stable operation of the beamline. Accordingly, we plan to replace the present muon monitor sensors with electron multiplier tubes (EMTs). We investigated the radiation tolerance and linearity response of EMTs using a 90 MeV electron beam. An EMTs was irradiated with electrons up to 470 nC. EMTs show higher radiation tolerance than the Si sensors which are presently used as one of the muon monitor detectors for the T2K long-baseline neutrino experiment at J-PARC. The integrated charge yield decrease is found to be less than 8% after a beam irradiation equivalent to 132 days of operation at the future J-PARC beam power of 1.3 MW. The EMTs show linearity better than $\pm$5% up to the future beam intensity. The observed yield decrease is likely due to dynode deterioration based on the detailed investigation. The studies described here confirm that EMTs can be used as a high-intensity muon beam monitor. From the reported results, we are proceeding with the installation in the J-PARC neutrino beamline., Comment: 20 pages,19 figures

Published
2024
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5. Updated T2K measurements of muon neutrino and antineutrino disappearance using 3.6 $\times$ 10$^{21}$ protons on target

Author

Abe, K., Akhlaq, N., Akutsu, R., Alarakia-Charles, H., Ali, A., Hakim, Y. I. Alj, Monsalve, S. Alonso, Alt, C., Andreopoulos, C., Antonova, M., Aoki, S., Arihara, T., Asada, Y., Ashida, Y., Atkin, E. T., Barbi, M., Barker, G. J., Barr, G., Barrow, D., Batkiewicz-Kwasniak, M., Bench, F., Berardi, V., Berns, L., Bhadra, S., Blanchet, A., Blondel, A., Bolognesi, S., Bonus, T., Bordoni, S., Boyd, S. B., Bravar, A., Bronner, C., Bron, S., Bubak, A., Avanzini, M. Buizza, Caballero, J. A., Calabria, N. F., Cao, S., Carabadjac, D., Carter, A. J., Cartwright, S. L., Casado, M. P., Catanesi, M. G., Cervera, A., Chakrani, J., Cherdack, D., Chong, P. S., Christodoulou, G., Chvirova, A., Cicerchia, M., Coleman, J., Collazuol, G., Cook, L., Cudd, A., Dalmazzone, C., Daret, T., Dasgupta, P., Davydov, Yu. I., De Roeck, A., De Rosa, G., Dealtry, T., Delogu, C. C., Densham, C., Dergacheva, A., Di Lodovico, F., Dolan, S., Douqa, D., Doyle, T. A., Drapier, O., Dumarchez, J., Dunne, P., Dygnarowicz, K., Eguchi, A., Emery-Schrenk, S., Erofeev, G., Ershova, A., Eurin, G., Fedorova, D., Fedotov, S., Feltre, M., Finch, A. J., Aguirre, G. A. Fiorentini, Fiorillo, G., Fitton, M. D., Patiño, J. M. Franco, Friend, M., Fujii, Y., Fukuda, Y., Furui, Y., Fusshoeller, K., Giannessi, L., Giganti, C., Glagolev, V., Gonin, M., Rosa, J. González, Goodman, E. A. G., Gorin, A., Grassi, M., Guigue, M., Hadley, D. R., Haigh, J. T., Hamacher-Baumann, P., Harris, D. A., Hartz, M., Hasegawa, T., Hassani, S., Hastings, N. C., Hayato, Y., Henaff, D., Hiramoto, A., Hogan, M., Holeczek, J., Holin, A., Holvey, T., Van, N. T. Hong, Honjo, T., Iacob, F., Ichikawa, A. K., Ikeda, M., Ishida, T., Ishitsuka, M., Israel, H. T., Iwamoto, K., Izmaylov, A., Izumi, N., Jakkapu, M., Jamieson, B., Jenkins, S. J., Jesús-Valls, C., Jiang, J. J., Ji, J. Y., Jonsson, P., Joshi, S., Jung, C. K., Jurj, P. B., Kabirnezhad, M., Kaboth, A. C., Kajita, T., Kakuno, H., Kameda, J., Kasetti, S. P., Kataoka, Y., Katayama, Y., Katori, T., Kawaue, M., Kearns, E., Khabibullin, M., Khotjantsev, A., Kikawa, T., Kikutani, H., King, S., Kiseeva, V., Kisiel, J., Kobata, T., Kobayashi, H., Kobayashi, T., Koch, L., Kodama, S., Konaka, A., Kormos, L. L., Koshio, Y., Kostin, A., Koto, T., Kowalik, K., Kudenko, Y., Kudo, Y., Kuribayashi, S., Kurjata, R., Kutter, T., Kuze, M., La Commara, M., Labarga, L., Lachner, K., Lagoda, J., Lakshmi, S. M., James, M. Lamers, Lamoureux, M., Langella, A., Laporte, J. -F., Last, D., Latham, N., Laveder, M., Lavitola, L., Lawe, M., Lee, Y., Lin, C., Lin, S. -K., Litchfield, R. P., Liu, S. L., Li, W., Longhin, A., Long, K. R., Moreno, A. Lopez, Ludovici, L., Lu, X., Lux, T., Machado, L. N., Magaletti, L., Mahn, K., Malek, M., Mandal, M., Manly, S., Marino, A. D., Marti-Magro, L., Martin, D. G. R., Martini, M., Martin, J. F., Maruyama, T., Matsubara, T., Matveev, V., Mauger, C., Mavrokoridis, K., Mazzucato, E., McCauley, N., McElwee, J., McFarland, K. S., McGrew, C., McKean, J., Mefodiev, A., Megias, G. D., Mehta, P., Mellet, L., Metelko, C., Mezzetto, M., Miller, E., Minamino, A., Mineev, O., Mine, S., Miura, M., Bueno, L. Molina, Moriyama, S., Morrison, P., Mueller, Th. A., Munford, D., Munteanu, L., Nagai, K., Nagai, Y., Nakadaira, T., Nakagiri, K., Nakahata, M., Nakajima, Y., Nakamura, A., Nakamura, H., Nakamura, K., Nakamura, K. D., Nakano, Y., Nakayama, S., Nakaya, T., Nakayoshi, K., Naseby, C. E. R., Ngoc, T. V., Nguyen, V. Q., Niewczas, K., Nishimori, S., Nishimura, Y., Nishizaki, K., Nosek, T., Nova, F., Novella, P., Nugent, J. C., O'Keeffe, H. M., O'Sullivan, L., Odagawa, T., Ogawa, T., Okada, R., Okinaga, W., Okumura, K., Okusawa, T., Ospina, N., Osu, L., Owen, R. A., Oyama, Y., Palladino, V., Paolone, V., Pari, M., Parlone, J., Parsa, S., Pasternak, J., Pavin, M., Payne, D., Penn, G. C., Pershey, D., Pickering, L., Pidcott, C., Pintaudi, G., Pistillo, C., Popov, B., Yrey, A. J. Portocarrero, Porwit, K., Posiadala-Zezula, M., Prabhu, Y. S., Pupilli, F., Quilain, B., Radermacher, T., Radicioni, E., Radics, B., Ramírez, M. A., Ratoff, P. N., Reh, M., Riccio, C., Rondio, E., Roth, S., Roy, N., Rubbia, A., Ruggeri, A. C., Ruggles, C. A., Rychter, A., Sakashita, K., Sánchez, F., Santucci, G., Schefke, T., Schloesser, C. M., Scholberg, K., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Sgalaberna, D., Shaikhiev, A., Shaker, F., Shiozawa, M., Shorrock, W., Shvartsman, A., Skrobova, N., Skwarczynski, K., Smyczek, D., Smy, M., Sobczyk, J. T., Sobel, H., Soler, F. J. P., Sonoda, Y., Speers, A. J., Spina, R., Suslov, I. A., Suvorov, S., Suzuki, A., Suzuki, S. Y., Suzuki, Y., Sztuc, A. A., Tada, M., Tairafune, S., Takayasu, S., Takeda, A., Takeuchi, Y., Takifuji, K., Tanaka, H. K., Tanigawa, H., Tanihara, Y., Tani, M., Teklu, A., Tereshchenko, V. V., Teshima, N., Thamm, N., Thompson, L. F., Toki, W., Touramanis, C., Towstego, T., Tsui, K. M., Tsukamoto, T., Tzanov, M., Uchida, Y., Vagins, M., Vargas, D., Varghese, M., Vasseur, G., Vilela, C., Villa, E., Vinning, W. G. S., Virginet, U., Vladisavljevic, T., Wachala, T., Wakabayashi, D., Walsh, J. G., Wang, Y., Wan, L., Wark, D., Wascko, M. O., Weber, A., Wendell, R., Wilking, M. J., Wilkinson, C., Wilson, J. R., Wood, K., Wret, C., Xia, J., Xu, Y. -h., Yamamoto, K., Yamamoto, T., Yanagisawa, C., Yang, G., Yano, T., Yasutome, K., Yershov, N., Yevarouskaya, U., Yokoyama, M., Yoshimoto, Y., Yoshimura, N., Yu, M., Zaki, R., Zalewska, A., Zalipska, J., Zaremba, K., Zarnecki, G., Zhao, X., Zhu, T., Ziembicki, M., Zimmerman, E. D., Zito, M., and Zsoldos, S.

Subjects
High Energy Physics - Experiment
Abstract

Muon neutrino and antineutrino disappearance probabilities are identical in the standard three-flavor neutrino oscillation framework, but CPT violation and non-standard interactions can violate this symmetry. In this work we report the measurements of $\sin^{2} \theta_{23}$ and $\Delta m_{32}^2$ independently for neutrinos and antineutrinos. The aforementioned symmetry violation would manifest as an inconsistency in the neutrino and antineutrino oscillation parameters. The analysis discussed here uses a total of 1.97$\times$10$^{21}$ and 1.63$\times$10$^{21}$ protons on target taken with a neutrino and antineutrino beam respectively, and benefits from improved flux and cross-section models, new near detector samples and more than double the data reducing the overall uncertainty of the result. No significant deviation is observed, consistent with the standard neutrino oscillation picture.

Published
2023

6. First measurement of muon neutrino charged-current interactions on hydrocarbon without pions in the final state using multiple detectors with correlated energy spectra at T2K

Author

Abe, K., Akhlaq, N., Akutsu, R., Alarakia-Charles, H., Ali, A., Hakim, Y. I. Alj, Monsalve, S. Alonso, Alt, C., Andreopoulos, C., Antonova, M., Aoki, S., Arihara, T., Asada, Y., Ashida, Y., Atkin, E. T., Barbi, M., Barker, G. J., Barr, G., Barrow, D., Batkiewicz-Kwasniak, M., Bench, F., Berardi, V., Berns, L., Bhadra, S., Blanchet, A., Blondel, A., Bolognesi, S., Bonus, T., Bordoni, S., Boyd, S. B., Bravar, A., Bronner, C., Bron, S., Bubak, A., Avanzini, M. Buizza, Caballero, J. A., Calabria, N. F., Cao, S., Carabadjac, D., Carter, A. J., Cartwright, S. L., Casado, M. P., Catanesi, M. G., Cervera, A., Chakrani, J., Cherdack, D., Chong, P. S., Christodoulou, G., Chvirova, A., Cicerchia, M., Coleman, J., Collazuol, G., Cook, L., Cudd, A., Dalmazzone, C., Daret, T., Dasgupta, P., Davydov, Yu. I., De Roeck, A., De Rosa, G., Dealtry, T., Delogu, C. C., Densham, C., Dergacheva, A., Di Lodovico, F., Dolan, S., Douqa, D., Doyle, T. A., Drapier, O., Dumarchez, J., Dunne, P., Dygnarowicz, K., Eguchi, A., Emery-Schrenk, S., Erofeev, G., Ershova, A., Eurin, G., Fedorova, D., Fedotov, S., Feltre, M., Finch, A. J., Aguirre, G. A. Fiorentini, Fiorillo, G., Fitton, M. D., Patiño, J. M. Franco, Friend, M., Fujii, Y., Fukuda, Y., Furui, Y., Fusshoeller, K., Giannessi, L., Giganti, C., Glagolev, V., Gonin, M., Rosa, J. González, Goodman, E. A. G., Gorin, A., Grassi, M., Guigue, M., Hadley, D. R., Haigh, J. T., Hamacher-Baumann, P., Harris, D. A., Hartz, M., Hasegawa, T., Hassani, S., Hastings, N. C., Hayato, Y., Henaff, D., Hiramoto, A., Hogan, M., Holeczek, J., Holin, A., Holvey, T., Van, N. T. Hong, Honjo, T., Iacob, F., Ichikawa, A. K., Ikeda, M., Ishida, T., Ishitsuka, M., Israel, H. T., Izmaylov, A., Izumi, N., Jakkapu, M., Jamieson, B., Jenkins, S. J., Jesús-Valls, C., Jiang, J. J., Ji, J. Y., Jonsson, P., Joshi, S., Jung, C. K., Jurj, P. B., Kabirnezhad, M., Kaboth, A. C., Kajita, T., Kakuno, H., Kameda, J., Kasetti, S. P., Kataoka, Y., Katori, T., Kawaue, M., Kearns, E., Khabibullin, M., Khotjantsev, A., Kikawa, T., King, S., Kiseeva, V., Kisiel, J., Kobata, T., Kobayashi, H., Kobayashi, T., Koch, L., Kodama, S., Konaka, A., Kormos, L. L., Koshio, Y., Kostin, A., Koto, T., Kowalik, K., Kudenko, Y., Kudo, Y., Kuribayashi, S., Kurjata, R., Kutter, T., Kuze, M., La Commara, M., Labarga, L., Lachner, K., Lagoda, J., Lakshmi, S. M., James, M. Lamers, Lamoureux, M., Langella, A., Laporte, J. -F., Last, D., Latham, N., Laveder, M., Lavitola, L., Lawe, M., Lee, Y., Lin, C., Lin, S. -K., Litchfield, R. P., Liu, S. L., Li, W., Longhin, A., Long, K. R., Moreno, A. Lopez, Ludovici, L., Lu, X., Lux, T., Machado, L. N., Magaletti, L., Mahn, K., Malek, M., Mandal, M., Manly, S., Marino, A. D., Marti-Magro, L., Martin, D. G. R., Martini, M., Martin, J. F., Maruyama, T., Matsubara, T., Matveev, V., Mauger, C., Mavrokoridis, K., Mazzucato, E., McCauley, N., McElwee, J., McFarland, K. S., McGrew, C., McKean, J., Mefodiev, A., Megias, G. D., Mehta, P., Mellet, L., Metelko, C., Mezzetto, M., Miller, E., Minamino, A., Mineev, O., Mine, S., Miura, M., Bueno, L. Molina, Moriyama, S., Morrison, P., Mueller, Th. A., Munford, D., Munteanu, L., Nagai, K., Nagai, Y., Nakadaira, T., Nakagiri, K., Nakahata, M., Nakajima, Y., Nakamura, A., Nakamura, H., Nakamura, K., Nakamura, K. D., Nakano, Y., Nakayama, S., Nakaya, T., Nakayoshi, K., Naseby, C. E. R., Ngoc, T. V., Nguyen, V. Q., Niewczas, K., Nishimori, S., Nishimura, Y., Nishizaki, K., Nosek, T., Nova, F., Novella, P., Nugent, J. C., O'Keeffe, H. M., O'Sullivan, L., Odagawa, T., Ogawa, T., Okinaga, W., Okumura, K., Okusawa, T., Ospina, N., Osu, L., Owen, R. A., Oyama, Y., Palladino, V., Paolone, V., Pari, M., Parlone, J., Parsa, S., Pasternak, J., Pavin, M., Payne, D., Penn, G. C., Pershey, D., Pickering, L., Pidcott, C., Pintaudi, G., Pistillo, C., Popov, B., Yrey, A. J. Portocarrero, Porwit, K., Posiadala-Zezula, M., Prabhu, Y. S., Pupilli, F., Quilain, B., Radermacher, T., Radicioni, E., Radics, B., Ramírez, M. A., Ratoff, P. N., Reh, M., Riccio, C., Rondio, E., Roth, S., Roy, N., Rubbia, A., Ruggeri, A. C., Ruggles, C. A., Rychter, A., Sakashita, K., Sánchez, F., Santucci, G., Schefke, T., Schloesser, C. M., Scholberg, K., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Sgalaberna, D., Shaikhiev, A., Shaker, F., Shiozawa, M., Shorrock, W., Shvartsman, A., Skrobova, N., Skwarczynski, K., Smyczek, D., Smy, M., Sobczyk, J. T., Sobel, H., Soler, F. J. P., Sonoda, Y., Speers, A. J., Spina, R., Suslov, I. A., Suvorov, S., Suzuki, A., Suzuki, S. Y., Suzuki, Y., Sztuc, A. A., Tada, M., Tairafune, S., Takayasu, S., Takeda, A., Takeuchi, Y., Takifuji, K., Tanaka, H. K., Tanigawa, H., Tani, M., Teklu, A., Tereshchenko, V. V., Teshima, N., Thamm, N., Thompson, L. F., Toki, W., Touramanis, C., Towstego, T., Tsui, K. M., Tsukamoto, T., Tzanov, M., Uchida, Y., Vagins, M., Vargas, D., Varghese, M., Vasseur, G., Vilela, C., Villa, E., Vinning, W. G. S., Virginet, U., Vladisavljevic, T., Wachala, T., Wakabayashi, D., Walsh, J. G., Wang, Y., Wan, L., Wark, D., Wascko, M. O., Weber, A., Wendell, R., Wilking, M. J., Wilkinson, C., Wilson, J. R., Wood, K., Wret, C., Xia, J., Xu, Y. -h., Yamamoto, K., Yamamoto, T., Yanagisawa, C., Yang, G., Yano, T., Yasutome, K., Yershov, N., Yevarouskaya, U., Yokoyama, M., Yoshimoto, Y., Yoshimura, N., Yu, M., Zaki, R., Zalewska, A., Zalipska, J., Zaremba, K., Zarnecki, G., Zhao, X., Zhu, T., Ziembicki, M., Zimmerman, E. D., Zito, M., and Zsoldos, S.

Subjects
High Energy Physics - Experiment
Abstract

This paper reports the first measurement of muon neutrino charged-current interactions without pions in the final state using multiple detectors with correlated energy spectra at T2K. The data was collected on hydrocarbon targets using the off-axis T2K near detector (ND280) and the on-axis T2K near detector (INGRID) with neutrino energy spectra peaked at 0.6 GeV and 1.1 GeV respectively. The correlated neutrino flux presents an opportunity to reduce the impact of the flux uncertainty and to study the energy dependence of neutrino interactions. The extracted double-differential cross sections are compared to several Monte Carlo neutrino-nucleus interaction event generators showing the agreement between both detectors individually and with the correlated result., Comment: Updated discussion in Sec. V-A; Updated author list

Published
2023
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7. Measurements of neutrino oscillation parameters from the T2K experiment using $3.6\times10^{21}$ protons on target

Author

The T2K Collaboration, Abe, K., Akhlaq, N., Akutsu, R., Ali, A., Monsalve, S. Alonso, Alt, C., Andreopoulos, C., Antonova, M., Aoki, S., Arihara, T., Asada, Y., Ashida, Y., Atkin, E. T., Barbi, M., Barker, G. J., Barr, G., Barrow, D., Batkiewicz-Kwasniak, M., Bench, F., Berardi, V., Berns, L., Bhadra, S., Blanchet, A., Blondel, A., Bolognesi, S., Bonus, T., Bordoni, S., Boyd, S. B., Bravar, A., Bronner, C., Bron, S., Bubak, A., Avanzini, M. Buizza, Caballero, J. A., Calabria, N. F., Cao, S., Carabadjac, D., Carter, A. J., Cartwright, S. L., Catanesi, M. G., Cervera, A., Chakrani, J., Cherdack, D., Chong, P. S., Christodoulou, G., Chvirova, A., Cicerchia, M., Coleman, J., Collazuol, G., Cook, L., Cudd, A., Dalmazzone, C., Daret, T., Davydov, Yu. I., De Roeck, A., De Rosa, G., Dealtry, T., Delogu, C. C., Densham, C., Dergacheva, A., Di Lodovico, F., Dolan, S., Douqa, D., Doyle, T. A., Drapier, O., Dumarchez, J., Dunne, P., Dygnarowicz, K., Eguchi, A., Emery-Schrenk, S., Erofeev, G., Ershova, A., Eurin, G., Fedorova, D., Fedotov, S., Feltre, M., Finch, A. J., Aguirre, G. A. Fiorentini, Fiorillo, G., Fitton, M. D., Patiño, J. M. Franco, Friend, M., Fujii, Y., Fukuda, Y., Fusshoeller, K., Giannessi, L., Giganti, C., Glagolev, V., Gonin, M., Rosa, J. González, Goodman, E. A. G., Gorin, A., Grassi, M., Guigue, M., Hadley, D. R., Haigh, J. T., Hamacher-Baumann, P., Harris, D. A., Hartz, M., Hasegawa, T., Hassani, S., Hastings, N. C., Hayato, Y., Henaff, D., Hiramoto, A., Hogan, M., Holeczek, J., Holin, A., Holvey, T., Van, N. T. Hong, Honjo, T., Iacob, F., Ichikawa, A. K., Ikeda, M., Ishida, T., Ishitsuka, M., Israel, H. T., Iwamoto, K., Izmaylov, A., Izumi, N., Jakkapu, M., Jamieson, B., Jenkins, S. J., Jesús-Valls, C., Jiang, J. J., Jonsson, P., Joshi, S., Jung, C. K., Jurj, P. B., Kabirnezhad, M., Kaboth, A. C., Kajita, T., Kakuno, H., Kameda, J., Kasetti, S. P., Kataoka, Y., Katayama, Y., Katori, T., Kawaue, M., Kearns, E., Khabibullin, M., Khotjantsev, A., Kikawa, T., Kikutani, H., King, S., Kiseeva, V., Kisiel, J., Kobata, T., Kobayashi, H., Kobayashi, T., Koch, L., Kodama, S., Konaka, A., Kormos, L. L., Koshio, Y., Kostin, A., Koto, T., Kowalik, K., Kudenko, Y., Kudo, Y., Kuribayashi, S., Kurjata, R., Kutter, T., Kuze, M., La Commara, M., Labarga, L., Lachner, K., Lagoda, J., Lakshmi, S. M., James, M. Lamers, Lamoureux, M., Langella, A., Laporte, J. -F., Last, D., Latham, N., Laveder, M., Lavitola, L., Lawe, M., Lee, Y., Lin, C., Lin, S. -K., Litchfield, R. P., Liu, S. L., Li, W., Longhin, A., Long, K. R., Moreno, A. Lopez, Ludovici, L., Lu, X., Lux, T., Machado, L. N., Magaletti, L., Mahn, K., Malek, M., Mandal, M., Manly, S., Marino, A. D., Marti-Magro, L., Martin, D. G. R., Martini, M., Martin, J. F., Maruyama, T., Matsubara, T., Matveev, V., Mauger, C., Mavrokoridis, K., Mazzucato, E., McCauley, N., McElwee, J., McFarland, K. S., McGrew, C., McKean, J., Mefodiev, A., Megias, G. D., Mehta, P., Mellet, L., Metelko, C., Mezzetto, M., Miller, E., Minamino, A., Mineev, O., Mine, S., Miura, M., Bueno, L. Molina, Moriyama, S., Morrison, P., Mueller, Th. A., Munford, D., Munteanu, L., Nagai, K., Nagai, Y., Nakadaira, T., Nakagiri, K., Nakahata, M., Nakajima, Y., Nakamura, A., Nakamura, H., Nakamura, K., Nakamura, K. D., Nakano, Y., Nakayama, S., Nakaya, T., Nakayoshi, K., Naseby, C. E. R., Ngoc, T. V., Nguyen, V. Q., Niewczas, K., Nishimori, S., Nishimura, Y., Nishizaki, K., Nosek, T., Nova, F., Novella, P., Nugent, J. C., O'Keeffe, H. M., O'Sullivan, L., Odagawa, T., Ogawa, T., Okada, R., Okinaga, W., Okumura, K., Okusawa, T., Ospina, N., Owen, R. A., Oyama, Y., Palladino, V., Paolone, V., Pari, M., Parlone, J., Parsa, S., Pasternak, J., Pavin, M., Payne, D., Penn, G. C., Pershey, D., Pickering, L., Pidcott, C., Pintaudi, G., Pistillo, C., Popov, B., Porwit, K., Posiadala-Zezula, M., Prabhu, Y. S., Pupilli, F., Quilain, B., Radermacher, T., Radicioni, E., Radics, B., Ramírez, M. A., Ratoff, P. N., Reh, M., Riccio, C., Rondio, E., Roth, S., Roy, N., Rubbia, A., Ruggeri, A. C., Ruggles, C. A., Rychter, A., Sakashita, K., Sánchez, F., Santucci, G., Schloesser, C. M., Scholberg, K., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Sgalaberna, D., Shaikhiev, A., Shaker, F., Shaykina, A., Shiozawa, M., Shorrock, W., Shvartsman, A., Skrobova, N., Skwarczynski, K., Smyczek, D., Smy, M., Sobczyk, J. T., Sobel, H., Soler, F. J. P., Sonoda, Y., Speers, A. J., Spina, R., Suslov, I. A., Suvorov, S., Suzuki, A., Suzuki, S. Y., Suzuki, Y., Sztuc, A. A., Tada, M., Tairafune, S., Takayasu, S., Takeda, A., Takeuchi, Y., Takifuji, K., Tanaka, H. K., Tanihara, Y., Tani, M., Teklu, A., Tereshchenko, V. V., Teshima, N., Thamm, N., Thompson, L. F., Toki, W., Touramanis, C., Towstego, T., Tsui, K. M., Tsukamoto, T., Tzanov, M., Uchida, Y., Vagins, M., Vargas, D., Varghese, M., Vasseur, G., Vilela, C., Villa, E., Vinning, W. G. S., Virginet, U., Vladisavljevic, T., Wachala, T., Walsh, J. G., Wang, Y., Wan, L., Wark, D., Wascko, M. O., Weber, A., Wendell, R., Wilking, M. J., Wilkinson, C., Wilson, J. R., Wood, K., Wret, C., Xia, J., Xu, Y. -h., Yamamoto, K., Yamamoto, T., Yanagisawa, C., Yang, G., Yano, T., Yasutome, K., Yershov, N., Yevarouskaya, U., Yokoyama, M., Yoshimoto, Y., Yoshimura, N., Yu, M., Zaki, R., Zalewska, A., Zalipska, J., Zaremba, K., Zarnecki, G., Zhao, X., Zhu, T., Ziembicki, M., Zimmerman, E. D., Zito, M., and Zsoldos, S.

Subjects
High Energy Physics - Experiment
Abstract

The T2K experiment presents new measurements of neutrino oscillation parameters using $19.7(16.3)\times10^{20}$ protons on target (POT) in (anti-)neutrino mode at the far detector (FD). Compared to the previous analysis, an additional $4.7\times10^{20}$ POT neutrino data was collected at the FD. Significant improvements were made to the analysis methodology, with the near-detector analysis introducing new selections and using more than double the data. Additionally, this is the first T2K oscillation analysis to use NA61/SHINE data on a replica of the T2K target to tune the neutrino flux model, and the neutrino interaction model was improved to include new nuclear effects and calculations. Frequentist and Bayesian analyses are presented, including results on $\sin^2\theta_{13}$ and the impact of priors on the $\delta_\mathrm{CP}$ measurement. Both analyses prefer the normal mass ordering and upper octant of $\sin^2\theta_{23}$ with a nearly maximally CP-violating phase. Assuming the normal ordering and using the constraint on $\sin^2\theta_{13}$ from reactors, $\sin^2\theta_{23}=0.561^{+0.021}_{-0.032}$ using Feldman--Cousins corrected intervals, and $\Delta{}m^2_{32}=2.494_{-0.058}^{+0.041}\times10^{-3}~\mathrm{eV^2}$ using constant $\Delta\chi^{2}$ intervals. The CP-violating phase is constrained to $\delta_\mathrm{CP}=-1.97_{-0.70}^{+0.97}$ using Feldman--Cousins corrected intervals, and $\delta_\mathrm{CP}=0,\pi$ is excluded at more than 90% confidence level. A Jarlskog invariant of zero is excluded at more than $2\sigma$ credible level using a flat prior in $\delta_\mathrm{CP}$, and just below $2\sigma$ using a flat prior in $\sin\delta_\mathrm{CP}$. When the external constraint on $\sin^2\theta_{13}$ is removed, $\sin^2\theta_{13}=28.0^{+2.8}_{-6.5}\times10^{-3}$, in agreement with measurements from reactor experiments. These results are consistent with previous T2K analyses.

Published
2023
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8. In situ XAFS–XRD study of the Zr–Y2O3 interaction at extra-high temperatures

Author

Ayumi Itoh, Satoru Matsuo, Kenta Yoshida, Kenji Konashi, Rikuto Ikuta, Keisuke Niino, Yuji Arita, Masaaki Kobata, Tatsuo Fukuda, Tohru Kobayashi, Hajime Tanida, and Tsuyoshi Yaita

Subjects
in situ xafs–xrd, zr–y2o3, extra-high temperature., Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798, Crystallography, QD901-999
Abstract

The in situ measurement technique for a metal/metal-oxide mixture at extra-high temperature above 2000 K has been desired in the field of nuclear safety engineering. In the present study, we succeeded in simultaneous XAFS–XRD measurements of the Zr oxidation [Zr + O → Zr(O) + ZrO2] up to 1952 K and ZrO2–Y2O3 reaction from 1952 to 2519 K. The chemical shift during Zr oxidation was observed in the absorption spectra around the Zr K-edge, and the interatomic cation–cation and cation–oxygen distances obtained by the fitting analysis of EXAFS during the Y2O3–ZrO2 reaction are explained. Also, the temperature dependency of the anharmonic effect was investigated by comparing the fitted second- and third-order cumulants with the theoretical ones in which the Morse potential was applied as an interatomic potential, giving a good explanation about the local structure dynamics. Finally, the applicability of the developed system to investigation of nuclear fuel materials, such as UO2–Zr, is discussed.

Published
2024
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9. Antimicrobial resistance among invasive Haemophilus influenzae strains: results of a Brazilian study carried out from 1996 through 2000

Author

Casagrande S.T., Landgraf I.M., Kobata A.M.M., Zanella R.C., and Bokermann S.

Subjects
Haemophilus influenzae, Meningitis, Antimicrobial resistance, Medicine (General), R5-920, Biology (General), QH301-705.5
Abstract

A total of 1712 strains of Haemophilus influenzae isolated from patients with invasive diseases were obtained from ten Brazilian states from 1996 to 2000. ß-Lactamase production was assessed and the minimum inhibitory concentrations (MIC) of ampicillin, chloramphenicol, ceftriaxone and rifampin were determined using a method for broth microdilution of Haemophilus test medium. The prevalence of strains producing ß-lactamase ranged from 6.6 to 57.7%, with an overall prevalence of 18.4%. High frequency of ß-lactamase-mediated ampicillin resistance was observed in Distrito Federal (25%), São Paulo (21.7%) and Paraná (18.5%). Of the 1712 strains analyzed, none was ß-lactamase negative, ampicillin resistant. A total of 16.8% of the strains were resistant to chloramphenicol, and 13.8% of these also presented resistance to ampicillin, and only 3.0% were resistant to chloramphenicol alone. All strains were susceptible to ceftriaxone and rifampin and the MIC90 were 0.015 µg/ml and 0.25 µg/ml, respectively. Ceftriaxone is the drug of choice for empirical treatment of bacterial meningitis in pediatric patients who have not been screened for drug susceptibility. The emergence of drug resistance is a serious challenge for the management of invasive H. influenzae disease, which emphasizes the fundamental role of laboratory-based surveillance for antimicrobial resistance.

Published
2002

12. Scintillator ageing of the T2K near detectors from 2010 to 2021

Author

The T2K Collaboration, Abe, K., Akhlaq, N., Akutsu, R., Ali, A., Alt, C., Andreopoulos, C., Antonova, M., Aoki, S., Arihara, T., Asada, Y., Ashida, Y., Atkin, E. T., Ban, S., Barbi, M., Barker, G. J., Barr, G., Barrow, D., Batkiewicz-Kwasniak, M., Bench, F., Berardi, V., Berns, L., Bhadra, S., Blanchet, A., Blondel, A., Bolognesi, S., Bonus, T., Bordoni, S., Boyd, S. B., Bravar, A., Bronner, C., Bron, S., Bubak, A., Avanzini, M. Buizza, Calabria, N. F., Cao, S., Carter, A. J., Cartwright, S. L., Catanesi, M. G., Cervera, A., Chakrani, J., Cherdack, D., Christodoulou, G., Cicerchia, M., Coleman, J., Collazuol, G., Cook, L., Cudd, A., Davydov, Yu. I., De Roeck, A., De Rosa, G., Dealtry, T., Delogu, C. C., Densham, C., Dergacheva, A., Di Lodovico, F., Dolan, S., Douqa, D., Doyle, T. A., Drapier, O., Duffy, K. E., Dumarchez, J., Dunne, P., Dygnarowicz, K., Eguchi, A., Emery-Schrenk, S., Ershova, A., Fedotov, S., Fernandez, P., Finch, A. J., Aguirre, G. A. Fiorentini, Fiorillo, G., Friend, M., Fujii, Y., Fukuda, Y., Fusshoeller, K., Giganti, C., Glagolev, V., Gonin, M., Goodman, E. A. G., Gorin, A., Grassi, M., Guigue, M., Hadley, D. R., Haigh, J. T., Hamacher-Baumann, P., Harris, D. A., Hartz, M., Hasegawa, T., Hassani, S., Hastings, N. C., Hatzikoutelis, A., Hayato, Y., Hiramoto, A., Hogan, M., Holeczek, J., Holin, A., Holvey, T. J., Van, N. T. Hong, Honjo, T., Iacob, F., Ichikawa, A. K., Ikeda, M., Ishida, T., Ishitsuka, M., Israel, H. T., Iwamoto, K., Izmaylov, A., Izumi, N., Jakkapu, M., Jamieson, B., Jenkins, S. J., Jesús-Valls, C., Jiang, J. J., Jonsson, P., Jung, C. K., Jurj, P. B., Kabirnezhad, M., Kaboth, A. C., Kajita, T., Kakuno, H., Kameda, J., Kasetti, S. P., Kataoka, Y., Katayama, Y., Katori, T., Kawaue, M., Kearns, E., Khabibullin, M., Khotjantsev, A., Kikawa, T., Kikutani, H., King, S., Kisiel, J., Knight, A., Kobata, T., Kobayashi, T., Koch, L., Kogan, G., Konaka, A., Kormos, L. L., Koshio, Y., Kostin, A., Kowalik, K., Kudenko, Y., Kuribayashi, S., Kurjata, R., Kutter, T., Kuze, M., La Commara, M., Labarga, L., Lagoda, J., Lakshmi, S. M., James, M. Lamers, Lamont, I., Lamoureux, M., Last, D., Latham, N., Laveder, M., Lawe, M., Lee, Y., Lin, C., Lindner, T., Lin, S. -K., Litchfield, R. P., Liu, S. L., Longhin, A., Long, K. R., Ludovici, L., Lu, X., Lux, T., Machado, L. N., Magaletti, L., Mahn, K., Malek, M., Mandal, M., Manly, S., Marino, A. D., Marti-Magro, L., Martin, D. G. R., Martini, M., Martin, J. F., Maruyama, T., Matsubara, T., Matveev, V., Mauger, C., Mavrokoridis, K., Mazzucato, E., McCauley, N., McElwee, J., McFarland, K. S., McGrew, C., Mefodiev, A., Megias, G. D., Mellet, L., Metelko, C., Mezzetto, M., Minamino, A., Mineev, O., Mine, S., Miura, M., Bueno, L. Molina, Moriyama, S., Mueller, Th. A., Munford, D., Munteanu, L., Nagai, K., Nagai, Y., Nakadaira, T., Nakagiri, K., Nakahata, M., Nakajima, Y., Nakamura, A., Nakamura, H., Nakamura, K., Nakano, Y., Nakayama, S., Nakaya, T., Nakayoshi, K., Naseby, C. E. R., Ngoc, T. V., Nguyen, V. Q., Niewczas, K., Nishimura, Y., Nishizaki, K., Nova, F., Novella, P., Nugent, J. C., O'Keeffe, H. M., O'Sullivan, L., Odagawa, T., Ogawa, T., Okada, R., Okumura, K., Okusawa, T., Owen, R. A., Oyama, Y., Palladino, V., Paolone, V., Pari, M., Parlone, J., Parsa, S., Pasternak, J., Pavin, M., Payne, D., Penn, G. C., Pershey, D., Pickering, L., Pidcott, C., Pintaudi, G., Pistillo, C., Popov, B., Porwit, K., Posiadala-Zezula, M., Prabhu, Y. S., Quilain, B., Radermacher, T., Radicioni, E., Radics, B., Ratoff, P. N., Reh, M., Riccio, C., Rondio, E., Roth, S., Rubbia, A., Ruggeri, A. C., Ruggles, C. A., Rychter, A., Sakashita, K., Sánchez, F., Santucci, G., Schloesser, C. M., Scholberg, K., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Sgalaberna, D., Shaikhiev, A., Shaykina, A., Shiozawa, M., Shorrock, W., Shvartsman, A., Skwarczynski, K., Smy, M., Sobczyk, J. T., Sobel, H., Soler, F. J. P., Sonoda, Y., Spina, R., Su, H., Suslov, I. A., Suvorov, S., Suzuki, A., Suzuki, S. Y., Suzuki, Y., Sztuc, A. A., Tada, M., Takayasu, S., Takeda, A., Takeuchi, Y., Tanaka, H. K., Tanihara, Y., Tani, M., Tereshchenko, V. V., Teshima, N., Thamm, N., Thompson, L. F., Toki, W., Touramanis, C., Towstego, T., Tsui, K. M., Tsukamoto, T., Tzanov, M., Uchida, Y., Vacheret, A., Vagins, M., Vargas, D., Vasseur, G., Vilela, C., Vinning, W. G. S., Vladisavljevic, T., Wachala, T., Walsh, J. G., Wang, Y., Wan, L., Wark, D., Wascko, M. O., Weber, A., Wendell, R., Wilking, M. J., Wilkinson, C., Wilson, J. R., Wood, K., Wret, C., Xia, J., Xu, Y. -h., Yamamoto, K., Yanagisawa, C., Yang, G., Yano, T., Yasutome, K., Yershov, N., Yevarouskaya, U., Yokoyama, M., Yoshimoto, Y., Yu, M., Zaki, R., Zalewska, A., Zalipska, J., Zaremba, K., Zarnecki, G., Zhao, X., Zhu, T., Ziembicki, M., Zimmerman, E. D., Zito, M., and Zsoldos, S.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

The T2K experiment widely uses plastic scintillator as a target for neutrino interactions and an active medium for the measurement of charged particles produced in neutrino interactions at its near detector complex. Over 10 years of operation the measured light yield recorded by the scintillator based subsystems has been observed to degrade by 0.9--2.2\% per year. Extrapolation of the degradation rate through to 2040 indicates the recorded light yield should remain above the lower threshold used by the current reconstruction algorithms for all subsystems. This will allow the near detectors to continue contributing to important physics measurements during the T2K-II and Hyper-Kamiokande eras. Additionally, work to disentangle the degradation of the plastic scintillator and wavelength shifting fibres shows that the reduction in light yield can be attributed to the ageing of the plastic scintillator., Comment: 29 pages, 18 figures. Prepared for submission to JINST

Published
2022

17. Physiological myocardial 18F-FDG uptake pattern in oncologic PET/CT: comparison with findings in cardiac sarcoidosis

Author

Takashi Norikane, Yuka Yamamoto, Yasukage Takami, Katsuya Mitamura, Takuya Kobata, Yukito Maeda, Takahisa Noma, and Yoshihiro Nishiyama

Subjects
18f-fdg, pet, physiological uptake, Medical physics. Medical radiology. Nuclear medicine, R895-920, Biology (General), QH301-705.5
Abstract

Objective(s): Physiological myocardial 18F-fluorodeoxyglucose (18F-FDG) uptake in oncologic positron emission tomography (PET)/computed tomography (CT) is commonly observed with multiple variations under clinical fasting conditions. The purpose of the present study was to evaluate physiological myocardial 18F-FDG uptake pattern by comparing with the results in cardiac sarcoidosis.Methods: A total of 174 examinations in 174 patients without cardiac disease and 27 examinations in 17 patients with cardiac sarcoidosis were performed. The polar map images generated from 18F-FDG PET/CT data were visually assessed as “basal-ring,” “focal,” and “focal on diffuse” patterns. Semi-quantitative analysis was also performed using the regional relative 18F-FDG uptake (% uptake).Results: On visual analysis, the “focal on diffuse” pattern was the most common in both examinations (43% and 59%, respectively). The physiological % uptake in the lateral and basal septal walls tended to be higher. Subgroup analysis showed significantly higher uptake in the mid-wall and left circumflex territory. In cardiac sarcoidosis patients, there was a significant difference only between segments 2 and 15 (p=0.04). No significant differences were observed between the base-mid-apical territory and coronary artery branch territory.Conclusion: High 18F-FDG uptake in the basal septal walls is likely to be observed as both physiological uptake in patients without cardiac disease and pathological uptake in patients with cardiac sarcoidosis.

Published
2024
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19. Impact of Lactate Clearance on Clinical and Neurological Outcomes of Patients With Out-of-Hospital Cardiac Arrest Treated With Extracorporeal Cardiopulmonary Resuscitation: A Secondary Data Analysis*

Author

Sugimoto, Momoko, Takayama, Wataru, Inoue, Akihiko, Hifumi, Toru, Sakamoto, Tetsuya, Kuroda, Yasuhiro, Otomo, Yasuhiro, Senda, Asae, Suzuki, Hajime, Tanimoto, Atsunori, Kitagawa, Kanta, Katayama, Yoichi, Igarashi, Nobuaki, Kawano, Masayuki, Kuroki, Yuji, Umehara, Tadashi, Sasaki, Yukari, Tominaga, Naoki, Hamaguchi, Takuro, Sakai, Takuma, Abe, Takeru, Hanafusa, Hiroaki, Yamaoka, Yuki, Kakizaki, Yumi, Sakato, Shinya, Kashiwabara, Shiho, Kadoya, Takashi, Misumi, Kayo, Kobayashi, Takaomi, Yamada, Sou, Kobayashi, Masakazu, Akashi, Naoko, Kuno, Masamune, Maruyama, Jun, Kobata, Hitoshi, Soh, Mitsuhito, Shirasaki, Kasumi, Shiba, Daiki, Isokawa, Shutaro, Uchida, Masatoshi, Sakurai, Atsushi, Tatsukawa, Hirotaka, Nishikawa, Marie, Kojima, Mitsuaki, Kosaki, Ryohei, Shimazui, Takashi, Kinoshita, Hiroki, Sawada, Yusuke, Yamamoto, Ryo, Masuzawa, Yuya, Matsumura, Kazuki, and Shimazaki, Junya

Published
2024
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20. First T2K measurement of transverse kinematic imbalance in the muon-neutrino charged-current single-$\pi^+$ production channel containing at least one proton

Author

Abe, K., Akhlaq, N., Akutsu, R., Ali, A., Alt, C., Andreopoulos, C., Antonova, M., Aoki, S., Arihara, T., Asada, Y., Ashida, Y., Atkin, E. T., Awataguchi, Y., Barker, G. J., Barr, G., Barrow, D., Batkiewicz-Kwasniak, M., Beloshapkin, A., Bench, F., Berardi, V., Berns, L., Bhadra, S., Blanchet, A., Blondel, A., Bolognesi, S., Bonus, T., Bourguille, B., Boyd, S. B., Bravar, A., Berguño, D. Bravo, Bronner, C., Bron, S., Bubak, A., Avanzini, M. Buizza, Cao, S., Cartwright, S. L., Catanesi, M. G., Cervera, A., Cherdack, D., Christodoulou, G., Cicerchia, M., Coleman, J., Collazuol, G., Cook, L., Coplowe, D., Cudd, A., De Rosa, G., Dealtry, T., Delogu, C. C., Dennis, S. R., Densham, C., Dergacheva, A., Di Lodovico, F., Dolan, S., Douqa, D., Doyle, T. A., Dumarchez, J., Dunne, P., Eguchi, A., Eklund, L., Emery-Schrenk, S., Ereditato, A., Finch, A. J., Fiorillo, G., Francois, C., Friend, M., Fujii, Y., Fukuda, R., Fukuda, Y., Fusshoeller, K., Giganti, C., Gonin, M., Gorin, A., Grassi, M., Guigue, M., Hadley, D. R., Hamacher-Baumann, P., Harris, D. A., Hartz, M., Hasegawa, T., Hassani, S., Hastings, N. C., Hayato, Y., Hiramoto, A., Hogan, M., Holeczek, J., Van, N. T. Hong, Honjo, T., Iacob, F., Ichikawa, A. K., Ikeda, M., Ishida, T., Ishitsuka, M., Iwamoto, K., Izmaylov, A., Izumi, N., Jakkapu, M., Jamieson, B., Jenkins, S. J., Jesús-Valls, C., Jonsson, P., Jung, C. K., Jurj, P. B., Kabirnezhad, M., Kakuno, H., Kameda, J., Kasetti, S. P., Kataoka, Y., Katayama, Y., Katori, T., Kearns, E., Khabibullin, M., Khotjantsev, A., Kikawa, T., Kikutani, H., King, S., Kisiel, J., Kobata, T., Kobayashi, T., Koch, L., Konaka, A., Kormos, L. L., Koshio, Y., Kostin, A., Kowalik, K., Kudenko, Y., Kuribayashi, S., Kurjata, R., Kutter, T., Kuze, M., Labarga, L., Lagoda, J., Lamoureux, M., Last, D., Laveder, M., Lawe, M., Litchfield, R. P., Liu, S. L., Longhin, A., Ludovici, L., Lu, X., Lux, T., Machado, L. N., Magaletti, L., Mahn, K., Malek, M., Manly, S., Maret, L., Marino, A. D., Marti-Magro, L., Maruyama, T., Matsubara, T., Matsushita, K., Mauger, C., Mavrokoridis, K., Mazzucato, E., McCauley, N., McElwee, J., McFarland, K. S., McGrew, C., Mefodiev, A., Mezzetto, M., Minamino, A., Mineev, O., Mine, S., Miura, M., Bueno, L. Molina, Moriyama, S., Mueller, Th. A., Munteanu, L., Nagai, Y., Nakadaira, T., Nakahata, M., Nakajima, Y., Nakamura, A., Nakamura, K., Nakano, Y., Nakayama, S., Nakaya, T., Nakayoshi, K., Naseby, C. E. R., Ngoc, T. V., Nguyen, V. Q., Niewczas, K., Nishimura, Y., Noah, E., Nonnenmacher, T. S., Nova, F., Nowak, J., Nugent, J. C., O'Keeffe, H. M., O'Sullivan, L., Odagawa, T., Ogawa, T., Okada, R., Okumura, K., Okusawa, T., Owen, R. A., Oyama, Y., Palladino, V., Paolone, V., Pari, M., Parker, W. C., Parsa, S., Pasternak, J., Pavin, M., Payne, D., Penn, G. C., Pershey, D., Pickering, L., Pidcott, C., Pintaudi, G., Pistillo, C., Popov, B., Porwit, K., Posiadala-Zezula, M., Quilain, B., Radermacher, T., Radicioni, E., Radics, B., Ratoff, P. N., Riccio, C., Rondio, E., Roth, S., Rubbia, A., Ruggeri, A. C., Ruggles, C., Rychter, A., Sakashita, K., Sánchez, F., Santucci, G., Schloesser, C. M., Scholberg, K., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Sgalaberna, D., Shaikhiev, A., Shaykina, A., Shiozawa, M., Shorrock, W., Shvartsman, A., Skwarczynski, K., Smy, M., Sobczyk, J. T., Sobel, H., Soler, F. J. P., Sonoda, Y., Spina, R., Suvorov, S., Suzuki, A., Suzuki, S. Y., Suzuki, Y., Sztuc, A. A., Tada, M., Tajima, M., Takeda, A., Takeuchi, Y., Tanaka, H. K., Tanihara, Y., Tani, M., Teshima, N., Thompson, L. F., Toki, W., Touramanis, C., Towstego, T., Tsui, K. M., Tsukamoto, T., Tzanov, M., Uchida, Y., Vagins, M., Valder, S., Vargas, D., Vasseur, G., Vilela, C., Vinning, W. G. S., Vladisavljevic, T., Wachala, T., Walker, J., Walsh, J. G., Wang, Y., Wan, L., Wark, D., Wascko, M. O., Weber, A., Wendell, R., Wilking, M. J., Wilkinson, C., Wilson, J. R., Wood, K., Wret, C., Xia, J., Xu, Y. -h., Yamamoto, K., Yanagisawa, C., Yang, G., Yano, T., Yasutome, K., Yershov, N., Yokoyama, M., Yoshida, T., Yoshimoto, Y., Yu, M., Zalewska, A., Zalipska, J., Zaremba, K., Zarnecki, G., Ziembicki, M., Zito, M., and Zsoldos, S.

Subjects
High Energy Physics - Experiment
Abstract

This paper reports the first T2K measurement of the transverse kinematic imbalance in the single-$\pi^+$ production channel of neutrino interactions. We measure the differential cross sections in the muon-neutrino charged-current interaction on hydrocarbon with a single $\pi^+$ and at least one proton in the final state, at the ND280 off-axis near detector of the T2K experiment. The extracted cross sections are compared to the predictions from different neutrino-nucleus interaction event generators. Overall, the results show a preference for models which have a more realistic treatment of nuclear medium effects including the initial nuclear state and final-state interactions.

Published
2021
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21. Improved constraints on neutrino mixing from the T2K experiment with $\mathbf{3.13\times10^{21}}$ protons on target

Author

T2K Collaboration, Abe, K., Akhlaq, N., Akutsu, R., Ali, A., Alt, C., Andreopoulos, C., Antonova, M., Aoki, S., Arihara, T., Asada, Y., Ashida, Y., Atkin, E. T., Awataguchi, Y., Barker, G. J., Barr, G., Barrow, D., Batkiewicz-Kwasniak, M., Beloshapkin, A., Bench, F., Berardi, V., Berns, L., Bhadra, S., Blanchet, A., Blondel, A., Bolognesi, S., Bonus, T., Bourguille, B., Boyd, S. B., Bravar, A., Bergu, D. Bravo, Bronner, C., Bron, S., Bubak, A., Avanzini, M. Buizza, Cao, S., Cartwright, S. L., Catanesi, M. G., Cervera, A., Cherdack, D., Christodoulou, G., Cicerchia, M., Coleman, J., Collazuol, G., Cook, L., Coplowe, D., Cudd, A., De Rosa, G., Dealtry, T., Delogu, C. C., Dennis, S. R., Densham, C., Dergacheva, A., Di Lodovico, F., Dolan, S., Douqa, D., Doyle, T. A., Dumarchez, J., Dunne, P., Eguchi, A., Eklund, L., Emery-Schrenk, S., Ereditato, A., Finch, A. J., Fiorillo, G., Francois, C., Friend, M., Fujii, Y., Fukuda, R., Fukuda, Y., Fusshoeller, K., Giganti, C., Gonin, M., Gorin, A., Grassi, M., Guigue, M., Hadley, D. R., Hamacher-Baumann, P., Harris, D. A., Hartz, M., Hasegawa, T., Hassani, S., Hastings, N. C., Hayato, Y., Hiramoto, A., Hogan, M., Holeczek, J., Van, N. T. Hong, Honjo, T., Iacob, F., Ichikawa, A. K., Ikeda, M., Ishida, T., Ishitsuka, M., Iwamoto, K., Izmaylov, A., Izumi, N., Jakkapu, M., Jamieson, B., Jenkins, S. J., Jes, C., Jonsson, P., Jung, C. K., Jurj, P. B., Kabirnezhad, M., Kakuno, H., Kameda, J., Kasetti, S. P., Kataoka, Y., Katayama, Y., Katori, T., Kearns, E., Khabibullin, M., Khotjantsev, A., Kikawa, T., Kikutani, H., King, S., Kisiel, J., Kobata, T., Kobayashi, T., Koch, L., Konaka, A., Kormos, L. L., Koshio, Y., Kostin, A., Kowalik, K., Kudenko, Y., Kuribayashi, S., Kurjata, R., Kutter, T., Kuze, M., Labarga, L., Lagoda, J., Lamoureux, M., Last, D., Laveder, M., Lawe, M., Litchfield, R. P., Liu, S. L., Longhin, A., Ludovici, L., Lu, X., Lux, T., Machado, L. N., Magaletti, L., Mahn, K., Malek, M., Manly, S., Maret, L., Marino, A. D., Marti-Magro, L., Maruyama, T., Matsubara, T., Matsushita, K., Mauger, C., Mavrokoridis, K., Mazzucato, E., McCauley, N., McElwee, J., McFarland, K. S., McGrew, C., Mefodiev, A., Mezzetto, M., Minamino, A., Mineev, O., Mine, S., Miura, M., Bueno, L. Molina, Moriyama, S., Mueller, Th. A., Munteanu, L., Nagai, Y., Nakadaira, T., Nakahata, M., Nakajima, Y., Nakamura, A., Nakamura, K., Nakano, Y., Nakayama, S., Nakaya, T., Nakayoshi, K., Naseby, C. E. R., Ngoc, T. V., Nguyen, V. Q., Niewczas, K., Nishimura, Y., Noah, E., Nonnenmacher, T. S., Nova, F., Nowak, J., Nugent, J. C., O'Keeffe, H. M., O'Sullivan, L., Odagawa, T., Ogawa, T., Okada, R., Okumura, K., Okusawa, T., Owen, R. A., Oyama, Y., Palladino, V., Paolone, V., Pari, M., Parker, W. C., Parsa, S., Pasternak, J., Pavin, M., Payne, D., Penn, G. C., Pickering, L., Pidcott, C., Pintaudi, G., Pistillo, C., Popov, B., Porwit, K., Posiadala-Zezula, M., Pritchard, A., Quilain, B., Radermacher, T., Radicioni, E., Radics, B., Ratoff, P. N., Riccio, C., Rondio, E., Roth, S., Rubbia, A., Ruggeri, A. C., Ruggles, C., Rychter, A., Sakashita, K., S, F., Santucci, G., Schloesser, C. M., Scholberg, K., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Sgalaberna, D., Shaikhiev, A., Shaykina, A., Shiozawa, M., Shorrock, W., Shvartsman, A., Skwarczynski, K., Smy, M., Sobczyk, J. T., Sobel, H., Soler, F. J. P., Sonoda, Y., Spina, R., Suvorov, S., Suzuki, A., Suzuki, S. Y., Suzuki, Y., Sztuc, A. A., Tada, M., Tajima, M., Takeda, A., Takeuchi, Y., Tanaka, H. K., Tanihara, Y., Tani, M., Teshima, N., Thompson, L. F., Toki, W., Touramanis, C., Towstego, T., Tsui, K. M., Tsukamoto, T., Tzanov, M., Uchida, Y., Vagins, M., Valder, S., Vargas, D., Vasseur, G., Vilela, C., Vinning, W. G. S., Vladisavljevic, T., Wachala, T., Walker, J., Walsh, J. G., Wang, Y., Wark, D., Wascko, M. O., Weber, A., Wendell, R., Wilking, M. J., Wilkinson, C., Wilson, J. R., Wood, K., Wret, C., Xia, J., Yamamoto, K., Yanagisawa, C., Yang, G., Yano, T., Yasutome, K., Yershov, N., Yokoyama, M., Yoshida, T., Yoshimoto, Y., Yu, M., Zalewska, A., Zalipska, J., Zaremba, K., Zarnecki, G., Ziembicki, M., Zito, M., and Zsoldos, S.

Subjects
High Energy Physics - Experiment
Abstract

The T2K experiment reports updated measurements of neutrino and antineutrino oscillations using both appearance and disappearance channels. This result comes from an exposure of $14.9~(16.4) \times 10^{20}$ protons on target in neutrino (antineutrino) mode. Significant improvements have been made to the neutrino interaction model and far detector reconstruction. An extensive set of simulated data studies have also been performed to quantify the effect interaction model uncertainties have on the T2K oscillation parameter sensitivity. T2K performs multiple oscillation analyses that present both frequentist and Bayesian intervals for the PMNS parameters. For fits including a constraint on \ssqthonethree from reactor data and assuming normal mass ordering T2K measures $\sin^2\theta_{23} = 0.53^{+0.03}_{-0.04}$ and $\Delta{}m^2_{32} = (2.45 \pm 0.07) \times 10^{-3}$ eV$^{2}$c$^{-4}$. The Bayesian analyses show a weak preference for normal mass ordering (89% posterior probability) and the upper $\sin^2\theta_{23}$ octant (80% posterior probability), with a uniform prior probability assumed in both cases. The T2K data exclude CP conservation in neutrino oscillations at the $2\sigma$ level., Comment: Update figure formatting

Published
2021
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23. Retrospective Observational Study of Patients With Subdural Hematoma Treated With Idarucizumab

Author

Eiichi Suehiro, Hideyuki Ishihara, Yohei Kogeichi, Tsunenori Ozawa, Koichi Haraguchi, Masaru Honda, Yumie Honda, Makoto Inaba, Ryusuke Kabeya, Naoaki Kanda, Kenta Koketsu, Nobukuni Murakami, Hidetoshi Nakamoto, Kotaro Oshio, Kuniyasu Saigusa, Takashi Shuto, Shuichi Sugiyama, Kenji Suzuyama, Tsuguaki Terashima, Mitsuharu Tsuura, Mitsutoshi Nakada, Hitoshi Kobata, Toshio Higashi, Nobuyuki Sakai, and Michiyasu Suzuki

Subjects
dabigatran, exacerbation, idarucizumab, reversal therapy, traumatic brain injury, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Use of anticoagulants is increasing with the aging of societies. The safe first-line drug is likely to be a direct oral anticoagulant (DOAC), but outcomes of treatment of traumatic brain injury (TBI) with anticoagulants are uncertain. Therefore, we examined the clinical effect of idarucizumab as reversal therapy in elderly patients with TBI who were treated with dabigatran. A retrospective multi-center observational study was performed in patients ?65 years of age who developed acute traumatic subdural hematoma during treatment with dabigatran and underwent reversal therapy with idarucizumab. The items examined included patient background, neurological and imaging findings at arrival, course after admission, complications, and outcomes. A total of 23 patients were enrolled in the study. The patients had a mean age of 78.9 years. Cause of TBI was fall in 60.9% of the subjects. Mean Glasgow Coma Scale score at arrival was 8.7; anisocoria was present in 31.8% of cases. Exacerbation of consciousness was found in 30.4%, but only in 13.3% of subjects treated with idarucizumab before consciousness and imaging findings worsened. Dabigatran was discontinued in 81.8% of cases after hematoma development, with a mean withdrawal period of 12.1 days. The favorable outcome rate was 21.7%, and mortality was 39.1%. In multi-variate analysis, timing of idarucizumab administration was associated with a favorable outcome. There were ischemic complications in 3 cases (13.1%), and all three events occurred ?7 days after administration of idarucizumab. These findings suggest that in cases that develop hematoma during treatment with dabigatran, it is important to administer idarucizumab early and restart dabigatran after conditions stabilize.

Published
2023
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24. T2K measurements of muon neutrino and antineutrino disappearance using $3.13\times 10^{21}$ protons on target

Author

Abe, K., Akhlaq, N., Akutsu, R., Ali, A., Alt, C., Andreopoulos, C., Antonova, M., Aoki, S., Arihara, T., Asada, Y., Ashida, Y., Atkin, E. T., Awataguchi, Y., Barker, G. J., Barr, G., Barrow, D., Batkiewicz-Kwasniak, M., Beloshapkin, A., Bench, F., Berardi, V., Berns, L., Bhadra, S., Bolognesi, S., Bonus, T., Bourguille, B., Boyd, S. B., Bravar, A., BravoBerguno, D., Bronner, C., Bron, S., Bubak, A., BuizzaAvanzini, M., Cao, S., Cartwright, S. L., Catanesi, M. G., Cervera, A., Cherdack, D., Christodoulou, G., Cicerchia, M., Coleman, J., Collazuol, G., Cook, L., Coplowe, D., Cudd, A., DeRosa, G., Dealtry, T., Delogu, C. C., Dennis, S. R., Densham, C., DiLodovico, F., Dolan, S., Doyle, T. A., Dumarchez, J., Dunne, P., Eguchi, A., Eklund, L., Emery-Schrenk, S., Ereditato, A., Finch, A. J., Fiorentini, G. A., Francois, C., Friend, M., Fujii, Y., Fukuda, R., Fukuda, Y., Fusshoeller, K., Giganti, C., Gonin, M., Gorin, A., Guigue, M., Hadley, D. R., Hamacher-Baumann, P., Hartz, M., Hasegawa, T., Hassani, S., Hastings, N. C., Hayato, Y., Hiramoto, A., Hogan, M., Holeczek, J., HongVan, N. T., Honjo, T., Iacob, F., Ichikawa, A. K., Ikeda, M., Ishida, T., Ishitsuka, M., Iwamoto, K., Izmaylov, A., Izumi, N., Jakkapu, M., Jamieson, B., Jenkins, S. J., Jesus-Valls, C., Jonsson, P., Junjie, X., Jurj, P. B., Kabirnezhad, M., Kakuno, H., Kameda, J., Abe, S. P. K., Blondel, A., Berguño, D. Bravo, Avanzini, M. Buizza, De Rosa, G., Dergacheva, A., Di Lodovico, F., Harris, D. A., Van, N. T. Hong, Jesús-Valls, C., Jung, C. K., Kasetti, S. P., Kataoka, Y., Katayama, Y., Katori, T., Kearns, E., Khabibullin, M., Khotjantsev, A., Kikawa, T., Kikutani, H., King, S., Kisiel, J., Kobata, T., Kobayashi, T., Koch, L., Konaka, A., Kormos, L. L., Koshio, Y., Kostin, A., Kowalik, K., Kudenko, Y., Kuribayashi, S., Kurjata, R., Kutter, T., Kuze, M., Labarga, L., Lagoda, J., Lamoureux, M., Last, D., Laveder, M., Lawe, M., Litchfield, R. P., Liu, S. L., Longhin, A., Ludovici, L., Lu, X., Lux, T., Machado, L. N., Magaletti, L., Mahn, K., Malek, M., Manly, S., Maret, L., Marino, A. D., Marti-Magro, L., Maruyama, T., Matsubara, T., Matsushita, K., Mauger, C., Mavrokoridis, K., Mazzucato, E., McCauley, N., McElwee, J., McFarland, K. S., McGrew, C., Mefodiev, A., Mezzetto, M., Minamino, A., Mineev, O., Mine, S., Miura, M., Bueno, L. Molina, Moriyama, S., Mueller, Th. A., Munteanu, L., Nagai, Y., Nakadaira, T., Nakahata, M., Nakajima, Y., Nakamura, A., Nakamura, K., Nakano, Y., Nakayama, S., Nakaya, T., Nakayoshi, K., Naseby, C. E. R., Ngoc, T. V., Nguyen, V. Q., Niewczas, K., Nishimura, Y., Noah, E., Nonnenmacher, T. S., Nova, F., Nowak, J., Nugent, J. C., O'Keeffe, H. M., O'Sullivan, L., Odagawa, T., Ogawa, T., Okada, R., Okumura, K., Okusawa, T., Owen, R. A., Oyama, Y., Palladino, V., Paolone, V., Pari, M., Parker, W. C., Parsa, S., Pasternak, J., Pavin, M., Payne, D., Penn, G. C., Pickering, L., Pidcott, C., Pintaudi, G., Pistillo, C., Popov, B., Porwit, K., Posiadala-Zezula, M., Pritchard, A., Quilain, B., Radermacher, T., Radicioni, E., Radics, B., Ratoff, P. N., Riccio, C., Rondio, E., Roth, S., Rubbia, A., Ruggeri, A. C., Ruggles, C., Rychter, A., Sakashita, K., Sánchez, F., Santucci, G., Schloesser, C. M., Scholberg, K., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Sgalaberna, D., Shaikhiev, A., Shaykina, A., Shiozawa, M., Shorrock, W., Shvartsman, A., Skwarczynski, K., Smy, M., Sobczyk, J. T., Sobel, H., Soler, F. J. P., Sonoda, Y., Spina, R., Suvorov, S., Suzuki, A., Suzuki, S. Y., Suzuki, Y., Sztuc, A. A., Tada, M., Tajima, M., Takeda, A., Takeuchi, Y., Tanaka, H. K., Tanihara, Y., Tani, M., Teshima, N., Thompson, L. F., Toki, W., Touramanis, C., Towstego, T., Tsui, K. M., Tsukamoto, T., Tzanov, M., Uchida, Y., Vagins, M., Valder, S., Vargas, D., Vasseur, G., Vilela, C., Vinning, W. G. S., Vladisavljevic, T., Wachala, T., Walker, J., Walsh, J. G., Wang, Y., Wark, D., Wascko, M. O., Weber, A., Wendell, R., Wilking, M. J., Wilkinson, C., Wilson, J. R., Wood, K., Wret, C., Xia, J., Yamamoto, K., Yanagisawa, C., Yang, G., Yano, T., Yasutome, K., Yershov, N., Yokoyama, M., Yoshida, T., Yoshimoto, Y., Yu, M., Zalewska, A., Zalipska, J., Zaremba, K., Zarnecki, G., Ziembicki, M., Zito, M., and Zsoldos, S.

Subjects
High Energy Physics - Experiment
Abstract

We report measurements by the T2K experiment of the parameters $\theta_{23}$ and $\Delta m^2_{32}$ which govern the disappearance of muon neutrinos and antineutrinos in the three-flavor PMNS neutrino oscillation model at T2K's neutrino energy and propagation distance. Utilizing the ability of the experiment to run with either a mainly neutrino or a mainly antineutrino beam, muon-like events from each beam mode are used to measure these parameters separately for neutrino and antineutrino oscillations. Data taken from $1.49 \times 10^{21}$ protons on target (POT) in neutrino mode and $1.64 \times 10^{21}$ POT in antineutrino mode are used. The best-fit values obtained by T2K were $\sin^2\left(\theta_{23}\right)=0.51^{+0.06}_{-0.07} \left(0.43^{+0.21}_{-0.05}\right)$ and $\Delta m^2_{32}=2.47^{+0.08}_{-0.09} \left(2.50^{+0.18}_{-0.13}\right)$\evmass for neutrinos (antineutrinos). No significant differences between the values of the parameters describing the disappearance of muon neutrinos and antineutrinos were observed. An analysis using an effective two-flavor neutrino oscillation model where the sine of the mixing angle is allowed to take non-physical values larger than 1 is also performed to check the consistency of our data with the three-flavor model. Our data were found to be consistent with a physical value for the mixing angle.

Published
2020
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25. Measurements of $\bar{\nu}_{\mu}$ and $\bar{\nu}_{\mu} + \nu_{\mu}$ charged-current cross-sections without detected pions nor protons on water and hydrocarbon at mean antineutrino energy of 0.86 GeV

Author

Abe, K., Akhlaq, N., Akutsu, R., Ali, A., Alt, C., Andreopoulos, C., Anthony, L., Antonova, M., Aoki, S., Ariga, A., Arihara, T., Asada, Y., Ashida, Y., Atkin, E. T., Awataguchi, Y., Ban, S., Barbi, M., Barker, G. J., Barr, G., Barrow, D., Barry, C., Batkiewicz-Kwasniak, M., Beloshapkin, A., Bench, F., Berardi, V., Berkman, S., Berns, L., Bhadra, S., Bienstock, S., Blondel, A., Bolognesi, S., Bonus, T., Bourguille, B., Boyd, S. B., Brailsford, D., Bravar, A., Berguño, D. Bravo, Bronner, C., Bron, S., Bubak, A., Avanzini, M. Buizza, Calcutt, J., Campbell, T., Cao, S., Cartwright, S. L., Catanesi, M. G., Cervera, A., Chappell, A., Checchia, C., Cherdack, D., Chikuma, N., Christodoulou, G., Cicerchia, M., Coleman, J., Collazuol, G., Cook, L., Coplowe, D., Cudd, A., Dabrowska, A., De Rosa, G., Dealtry, T., Denner, P. F., Dennis, S. R., Densham, C., Di Lodovico, F., Dokania, N., Dolan, S., Doyle, T. A., Drapier, O., Dumarchez, J., Dunne, P., Eguchi, A., Eklund, L., Emery-Schrenk, S., Ereditato, A., Fernandez, P., Feusels, T., Finch, A. J., Fiorentini, G. A., Fiorillo, G., Francois, C., Friend, M., Fujii, Y., Fujita, R., Fukuda, D., Fukuda, R., Fukuda, Y., Fusshoeller, K., Gameil, K., Giganti, C., Golan, T., Gonin, M., Gorin, A., Guigue, M., Hadley, D. R., Haigh, J. T., Hamacher-Baumann, P., Hartz, M., Hasegawa, T., Hassani, S., Hastings, N. C., Hayashino, T., Hayato, Y., Hiramoto, A., Hogan, M., Holeczek, J., Van, N. T. Hong, Honjo, T., Iacob, F., Ichikawa, A. K., Ikeda, M., Ishida, T., Ishii, T., Ishitsuka, M., Iwamoto, K., Izmaylov, A., Izumi, N., Jakkapu, M., Jamieson, B., Jenkins, S. J., Jesús-Valls, C., Jiang, M., Johnson, S., Jonsson, P., Jung, C. K., Junjie, X., Kabirnezhad, M., Kaboth, A. C., Kajita, T., Kakuno, H., Kameda, J., Karlen, D., Kasetti, K., Kataoka, Y., Katayama, Y., Katori, T., Kato, Y., Kearns, E., Khabibullin, M., Khotjantsev, A., Kikawa, T., Kikutani, H., Kim, H., Kim, J., King, S., Kisiel, J., Knight, A., Knox, A., Kobata, T., Kobayashi, T., Koch, L., Koga, T., Konaka, A., Kormos, L. L., Koshio, Y., Kostin, A., Kowalik, K., Kubo, H., Kudenko, Y., Kukita, N., Kuribayashi, S., Kurjata, R., Kutter, T., Kuze, M., Labarga, L., Lagoda, J., Lamoureux, M., Last, D., Laveder, M., Lawe, M., Licciardi, M., Lindner, T., Litchfield, R. P., Liu, S. L., Li, X., Longhin, A., Ludovici, L., Lu, X., Lux, T., Machado, L. N., Magaletti, L., Mahn, K., Malek, M., Manly, S., Maret, L., Marino, A. D., Marti-Magro, L., Martin, J. F., Maruyama, T., Matsubara, T., Matsushita, K., Matveev, V., Mauger, C., Mavrokoridis, K., Mazzucato, E., McCarthy, M., McCauley, N., McElwee, J., McFarland, K. S., McGrew, C., Mefodiev, A., Metelko, C., Mezzetto, M., Minamino, A., Mineev, O., Mine, S., Miura, M., Bueno, L. Molina, Moriyama, S., Morrison, J., Mueller, Th. A., Munteanu, L., Murphy, S., Nagai, Y., Nakadaira, T., Nakahata, M., Nakajima, Y., Nakamura, A., Nakamura, K. G., Nakamura, K., Nakayama, S., Nakaya, T., Nakayoshi, K., Nantais, C., Naseby, C. E. R., Ngoc, T. V., Niewczas, K., Nishikawa, K., Nishimura, Y., Noah, E., Nonnenmacher, T. S., Nova, F., Novella, P., Nowak, J., Nugent, J. C., O'Keeffe, H. M., O'Sullivan, L., Odagawa, T., Ogawa, T., Okada, R., Okumura, K., Okusawa, T., Oser, S. M., Owen, R. A., Oyama, Y., Palladino, V., Palomino, J. L., Paolone, V., Pari, M., Parker, W. C., Parsa, S., Pasternak, J., Paudyal, P., Pavin, M., Payne, D., Penn, G. C., Pickering, L., Pidcott, C., Pintaudi, G., Guerra, E. S. Pinzon, Pistillo, C., Popov, B., Porwit, K., Posiadala-Zezula, M., Pritchard, A., Quilain, B., Radermacher, T., Radicioni, E., Radics, B., Ratoff, P. N., Reinherz-Aronis, E., Riccio, C., Rondio, E., Roth, S., Rubbia, A., Ruggeri, A. C., Ruggles, C., Rychter, A., Sakashita, K., Sánchez, F., Santucci, G., Schloesser, C. M., Scholberg, K., Schwehr, J., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Sgalaberna, D., Shah, R., Shaikhiev, A., Shaker, F., Shaykina, A., Shiozawa, M., Shorrock, W., Shvartsman, A., Smirnov, A., Smy, M., Sobczyk, J. T., Sobel, H., Soler, F. J. P., Sonoda, Y., Steinmann, J., Suvorov, S., Suzuki, A., Suzuki, S. Y., Suzuki, Y., Sztuc, A. A., Tada, M., Tajima, M., Takeda, A., Takeuchi, Y., Tanaka, H. K., Tanaka, H. A., Tanaka, S., Tanihara, Y., Teshima, N., Thompson, L. F., Toki, W., Touramanis, C., Towstego, T., Tsui, K. M., Tsukamoto, T., Tzanov, M., Uchida, Y., Uno, W., Vagins, M., Valder, S., Vallari, Z., Vargas, D., Vasseur, G., Vilela, C., Vinning, W. G. S., Vladisavljevic, T., Volkov, V. V., Wachala, T., Walker, J., Walsh, J. G., Wang, Y., Wark, D., Wascko, M. O., Weber, A., Wendell, R., Wilking, M. J., Wilkinson, C., Wilson, J. R., Wilson, R. J., Wood, K., Wret, C., Yamada, Y., Yamamoto, K., Yanagisawa, C., Yang, G., Yano, T., Yasutome, K., Yen, S., Yershov, N., Yokoyama, M., Yoshida, T., Yu, M., Zalewska, A., Zalipska, J., Zaremba, K., Zarnecki, G., Ziembicki, M., Zimmerman, E. D., Zito, M., Zsoldos, S., and Zykova, A.

Subjects
High Energy Physics - Experiment
Abstract

We report measurements of the flux-integrated $\bar{\nu}_\mu$ and $\bar{\nu}_\mu+\nu_\mu$ charged-current cross-sections on water and hydrocarbon targets using the T2K anti-neutrino beam, with a mean neutrino energy of 0.86 GeV. The signal is defined as the (anti-)neutrino charged-current interaction with one induced $\mu^\pm$ and no detected charged pion nor proton. These measurements are performed using a new WAGASCI module recently added to the T2K setup in combination with the INGRID Proton module. The phase space of muons is restricted to the high-detection efficiency region, $p_{\mu}>400~{\rm MeV}/c$ and $\theta_{\mu}<30^{\circ}$, in the laboratory frame. Absence of pions and protons in the detectable phase space of "$p_{\pi}>200~{\rm MeV}/c$ and $\theta_{\pi}<70^{\circ}$", and "$p_{\rm p}>600~{\rm MeV}/c$ and $\theta_{\rm p}<70^{\circ}$" is required. In this paper, both of the $\bar{\nu}_\mu$ cross-sections and $\bar{\nu}_\mu+\nu_\mu$ cross-sections on water and hydrocarbon targets, and their ratios are provided by using D'Agostini unfolding method. The results of the integrated $\bar{\nu}_\mu$ cross-section measurements over this phase space are $\sigma_{\rm H_{2}O}\,=\,(1.082\pm0.068(\rm stat.)^{+0.145}_{-0.128}(\rm syst.)) \times 10^{-39}~{\rm cm^{2}/nucleon}$, $\sigma_{\rm CH}\,=\,(1.096\pm0.054(\rm stat.)^{+0.132}_{-0.117}(\rm syst.)) \times 10^{-39}~{\rm cm^{2}/nucleon}$, and $\sigma_{\rm H_{2}O}/\sigma_{\rm CH} = 0.987\pm0.078(\rm stat.)^{+0.093}_{-0.090}(\rm syst.)$. The $\bar{\nu}_\mu+\nu_\mu$ cross-section is $\sigma_{\rm H_{2}O} = (1.155\pm0.064(\rm stat.)^{+0.148}_{-0.129}(\rm syst.)) \times 10^{-39}~{\rm cm^{2}/nucleon}$, $\sigma_{\rm CH}\,=\,(1.159\pm0.049(\rm stat.)^{+0.129}_{-0.115}(\rm syst.)) \times 10^{-39}~{\rm cm^{2}/nucleon}$, and $\sigma_{\rm H_{2}O}/\sigma_{\rm CH}\,=\,0.996\pm0.069(\rm stat.)^{+0.083}_{-0.078}(\rm syst.)$.

Published
2020
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26. Simultaneous measurement of the muon neutrino charged-current cross section on oxygen and carbon without pions in the final state at T2K

Author

Abe, K., Akhlaq, N., Akutsu, R., Ali, A., Alt, C., Andreopoulos, C., Anthony, L., Antonova, M., Aoki, S., Ariga, A., Arihara, T., Asada, Y., Ashida, Y., Atkin, E. T., Awataguchi, Y., Ban, S., Barbi, M., Barker, G. J., Barr, G., Barrow, D., Batkiewicz-Kwasniak, M., Beloshapkin, A., Bench, F., Berardi, V., Berns, L., Bhadra, S., Bienstock, S., Bolognesi, S., Bonus, T., Bourguille, B., Boyd, S. B., Bravar, A., Berguño, D. Bravo, Bronner, C., Bron, S., Bubak, A., Avanzini, M. Buizza, Campbell, T., Cao, S., Cartwright, S. L., Catanesi, M. G., Cervera, A., Cherdack, D., Chikuma, N., Christodoulou, G., Cicerchia, M., Coleman, J., Collazuol, G., Cook, L., Coplowe, D., Cudd, A., Dabrowska, A., De Rosa, G., Dealtry, T., Dennis, S. R., Densham, C., Di Lodovico, F., Dokania, N., Dolan, S., Doyle, T. A., Drapier, O., Dumarchez, J., Dunne, P., Eguchi, A., Eklund, L., Emery-Schrenk, S., Ereditato, A., Finch, A. J., Fiorentini, G. A., Fiorillo, G., Francois, C., Friend, M., Fujii, Y., Fujita, R., Fukuda, D., Fukuda, R., Fukuda, Y., Fusshoeller, K., Giganti, C., Gonin, M., Gorin, A., Guigue, M., Hadley, D. R., Haigh, J. T., Hamacher-Baumann, P., Hartz, M., Hasegawa, T., Hassani, S., Hastings, N. C., Hayato, Y., Hiramoto, A., Hogan, M., Holeczek, J., Van, N. T. Hong, Honjo, T., Iacob, F., Ichikawa, A. K., Ikeda, M., Ishida, T., Ishitsuka, M., Iwamoto, K., Izmaylov, A., Izumi, N., Jakkapu, M., Jamieson, B., Jenkins, S. J., Jesús-Valls, C., Jiang, M., Jonsson, P., Jung, C. K., Junjie, X., Jurj, P. B., Kabirnezhad, M., Kaboth, A. C., Kajita, T., Kakuno, H., Kameda, J., Karlen, D., Kasetti, S. P., Kataoka, Y., Katayama, Y., Katori, T., Kato, Y., Kearns, E., Khabibullin, M., Khotjantsev, A., Kikawa, T., Kikutani, H., Kim, H., King, S., Kisiel, J., Knight, A., Kobata, T., Kobayashi, T., Koch, L., Koga, T., Konaka, A., Kormos, L. L., Koshio, Y., Kostin, A., Kowalik, K., Kubo, H., Kudenko, Y., Kukita, N., Kuribayashi, S., Kurjata, R., Kutter, T., Kuze, M., Labarga, L., Lagoda, J., Lamoureux, M., Last, D., Lawe, M., Licciardi, M., Litchfield, R. P., Liu, S. L., Li, X., Longhin, A., Ludovici, L., Lu, X., Lux, T., Machado, L. N., Magaletti, L., Mahn, K., Malek, M., Manly, S., Maret, L., Marino, A. D., Marti-Magro, L., Maruyama, T., Matsubara, T., Matsushita, K., Matveev, V., Mauger, C., Mavrokoridis, K., Mazzucato, E., McCauley, N., McElwee, J., McFarland, K. S., McGrew, C., Mefodiev, A., Metelko, C., Mezzetto, M., Minamino, A., Mineev, O., Mine, S., Miura, M., Bueno, L. Molina, Moriyama, S., Mueller, Th. A., Munteanu, L., Murphy, S., Nagai, Y., Nakadaira, T., Nakahata, M., Nakajima, Y., Nakamura, A., Nakamura, K., Nakayama, S., Nakaya, T., Nakayoshi, K., Naseby, C. E. R., Ngoc, T. V., Niewczas, K., Nishikawa, K., Nishimura, Y., Noah, E., Nonnenmacher, T. S., Nova, F., Novella, P., Nowak, J., Nugent, J. C., O'Keeffe, H. M., O'Sullivan, L., Odagawa, T., Ogawa, T., Okada, R., Okumura, K., Okusawa, T., Oser, S. M., Owen, R. A., Oyama, Y., Palladino, V., Paolone, V., Pari, M., Parker, W. C., Parsa, S., Pasternak, J., Pavin, M., Payne, D., Penn, G. C., Pickering, L., Pidcott, C., Pintaudi, G., Pistillo, C., Popov, B., Porwit, K., Posiadala-Zezula, M., Pritchard, A., Quilain, B., Radermacher, T., Radicioni, E., Radics, B., Ratoff, P. N., Riccio, C., Rondio, E., Roth, S., Rubbia, A., Ruggeri, A. C., Ruggles, C., Rychter, A., Sakashita, K., Sánchez, F., Santucci, G., Schloesser, C. M., Scholberg, K., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Sgalaberna, D., Shaikhiev, A., Shaykina, A., Shiozawa, M., Shorrock, W., Shvartsman, A., Smy, M., Sobczyk, J. T., Sobel, H., Soler, F. J. P., Sonoda, Y., Suvorov, S., Suzuki, A., Suzuki, S. Y., Suzuki, Y., Sztuc, A. A., Tada, M., Tajima, M., Takeda, A., Takeuchi, Y., Tanaka, H. K., Tanaka, H. A., Tanaka, S., Tanihara, Y., Tani, M., Teshima, N., Thompson, L. F., Toki, W., Touramanis, C., Towstego, T., Tsui, K. M., Tsukamoto, T., Tzanov, M., Uchida, Y., Vagins, M., Valder, S., Vallari, Z., Vargas, D., Vasseur, G., Vinning, W. G. S., Vladisavljevic, T., Volkov, V. V., Wachala, T., Walker, J., Walsh, J. G., Wang, Y., Wark, D., Wascko, M. O., Weber, A., Wendell, R., Wilking, M. J., Wilkinson, C., Wilson, J. R., Wood, K., Wret, C., Yamamoto, K., Yanagisawa, C., Yang, G., Yano, T., Yasutome, K., Yershov, N., Yokoyama, M., Yoshida, T., Yu, M., Zalewska, A., Zalipska, J., Zaremba, K., Zarnecki, G., Ziembicki, M., Zimmerman, E. D., Zito, M., Zsoldos, S., and Zykova, A.

Subjects
High Energy Physics - Experiment
Abstract

This paper reports the first simultaneous measurement of the double differential muon neutrino charged-current cross section on oxygen and carbon without pions in the final state as a function of the outgoing muon kinematics, made at the ND280 off-axis near detector of the T2K experiment. The ratio of the oxygen and carbon cross sections is also provided to help validate various models' ability to extrapolate between carbon and oxygen nuclear targets, as is required in T2K oscillation analyses. The data are taken using a neutrino beam with an energy spectrum peaked at 0.6 GeV. The extracted measurement is compared with the prediction from different Monte Carlo neutrino-nucleus interaction event generators, showing particular model separation for very forward-going muons. Overall, of the models tested, the result is best described using Local Fermi Gas descriptions of the nuclear ground state with RPA suppression.

Published
2020
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27. In-hospital extracorporeal cardiopulmonary resuscitation for patients with out-of-hospital cardiac arrest: an analysis by time-dependent propensity score matching using a nationwide database in Japan

Author

Okada, Yohei, Komukai, Sho, Irisawa, Taro, Yamada, Tomoki, Yoshiya, Kazuhisa, Park, Changhwi, Nishimura, Tetsuro, Ishibe, Takuya, Kobata, Hitoshi, Kiguchi, Takeyuki, Kishimoto, Masafumi, Kim, Sung-Ho, Ito, Yusuke, Sogabe, Taku, Morooka, Takaya, Sakamoto, Haruko, Suzuki, Keitaro, Onoe, Atsunori, Matsuyama, Tasuku, Nishioka, Norihiro, Matsui, Satoshi, Yoshimura, Satoshi, Kimata, Shunsuke, Kawai, Shunsuke, Makino, Yuto, Kiyohara, Kosuke, Zha, Ling, Ong, Marcus Eng Hock, Iwami, Taku, and Kitamura, Tetsuhisa

Published
2023
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29. Measurement of the charged-current electron (anti-)neutrino inclusive cross-sections at the T2K off-axis near detector ND280

Author

Abe, K., Akhlaq, N., Akutsu, R., Ali, A., Alt, C., Andreopoulos, C., Anthony, L., Antonova, M., Aoki, S., Ariga, A., Arihara, T., Asada, Y., Ashida, Y., Atkin, E. T., Awataguchi, Y., Ban, S., Barbi, M., Barker, G. J., Barr, G., Barrow, D., Barry, C., Batkiewicz-Kwasniak, M., Beloshapkin, A., Bench, F., Berardi, V., Berns, L., Bhadra, S., Bienstock, S., Blondel, A., Bolognesi, S., Bonus, T., Bourguille, B., Boyd, S. B., Brailsford, D., Bravar, A., Berguño, D. Bravo, Bronner, C., Bron, S., Bubak, A., Avanzini, M. Buizza, Calcutt, J., Campbell, T., Cao, S., Cartwright, S. L., Catanesi, M. G., Cervera, A., Chappell, A., Checchia, C., Cherdack, D., Chikuma, N., Christodoulou, G., Cicerchia, M., Coleman, J., Collazuol, G., Cook, L., Coplowe, D., Cudd, A., Dabrowska, A., De Rosa, G., Dealtry, T., Denner, P. F., Dennis, S. R., Densham, C., Di Lodovico, F., Dokania, N., Dolan, S., Doyle, T. A., Drapier, O., Dumarchez, J., Dunne, P., Eguchi, A., Eklund, L., Emery-Schrenk, S., Ereditato, A., Fernandez, P., Feusels, T., Finch, A. J., Fiorentini, G. A., Fiorillo, G., Francois, C., Friend, M., Fujii, Y., Fujita, R., Fukuda, D., Fukuda, R., Fukuda, Y., Fusshoeller, K., Giganti, C., Golan, T., Gonin, M., Gorin, A., Guigue, M., Hadley, D. R., Haigh, J. T., Hamacher-Baumann, P., Hartz, M., Hasegawa, T., Hassani, S., Hastings, N. C., Hayashino, T., Hayato, Y., Hiramoto, A., Hogan, M., Holeczek, J., Van, N. T. Hong, Honjo, T., Iacob, F., Ichikawa, A. K., Ikeda, M., Ishida, T., Ishii, T., Ishitsuka, M., Iwamoto, K., Izmaylov, A., Izumi, N., Jakkapu, M., Jamieson, B., Jenkins, S. J., Jesús-Valls, C., Jiang, M., Johnson, S., Jonsson, P., Jung, C. K., Jurj, P. B., Kabirnezhad, M., Kaboth, A. C., Kajita, T., Kakuno, H., Kameda, J., Karlen, D., Kasetti, S. P., Kataoka, Y., Katayama, Y., Katori, T., Kato, Y., Kearns, E., Khabibullin, M., Khotjantsev, A., Kikawa, T., Kikutani, H., Kim, H., King, S., Kisiel, J., Knight, A., Knox, A., Kobata, T., Kobayashi, T., Koch, L., Koga, T., Konaka, A., Kormos, L. L., Koshio, Y., Kostin, A., Kowalik, K., Kubo, H., Kudenko, Y., Kukita, N., Kuribayashi, S., Kurjata, R., Kutter, T., Kuze, M., Labarga, L., Lagoda, J., Lamoureux, M., Last, D., Laveder, M., Lawe, M., Licciardi, M., Lindner, T., Litchfield, R. P., Liu, S. L., Li, X., Longhin, A., Ludovici, L., Lu, X., Lux, T., Machado, L. N., Magaletti, L., Mahn, K., Malek, M., Manly, S., Maret, L., Marino, A. D., Marti-Magro, L., Martin, J. F., Maruyama, T., Matsubara, T., Matsushita, K., Matveev, V., Mauger, C., Mavrokoridis, K., Mazzucato, E., McCarthy, M., McCauley, N., McElwee, J., McFarland, K. S., McGrew, C., Mefodiev, A., Metelko, C., Mezzetto, M., Minamino, A., Mineev, O., Mine, S., Miura, M., Bueno, L. Molina, Moriyama, S., Morrison, J., Mueller, Th. A., Munteanu, L., Murphy, S., Nagai, Y., Nakadaira, T., Nakahata, M., Nakajima, Y., Nakamura, A., Nakamura, K. G., Nakamura, K., Nakano, Y., Nakayama, S., Nakaya, T., Nakayoshi, K., Nantais, C., Naseby, C. E. R., Ngoc, T. V., Niewczas, K., Nishikawa, K., Nishimura, Y., Noah, E., Nonnenmacher, T. S., Nova, F., Novella, P., Nowak, J., Nugent, J. C., O'Keeffe, H. M., O'Sullivan, L., Odagawa, T., Ogawa, T., Okada, R., Okumura, K., Okusawa, T., Oser, S. M., Owen, R. A., Oyama, Y., Palladino, V., Palomino, J. L., Paolone, V., Pari, M., Parker, W. C., Parsa, S., Pasternak, J., Paudyal, P., Pavin, M., Payne, D., Penn, G. C., Pickering, L., Pidcott, C., Pintaudi, G., Guerra, E. S. Pinzon, Pistillo, C., Popov, B., Porwit, K., Posiadala-Zezula, M., Pritchard, A., Quilain, B., Radermacher, T., Radicioni, E., Radics, B., Ratoff, P. N., Reinherz-Aronis, E., Riccio, C., Rondio, E., Roth, S., Rubbia, A., Ruggeri, A. C., Ruggles, C., Rychter, A., Sakashita, K., Sánchez, F., Santucci, G., Schloesser, C. M., Scholberg, K., Schwehr, J., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Sgalaberna, D., Shah, R., Shaikhiev, A., Shaker, F., Shaykina, A., Shiozawa, M., Shorrock, W., Shvartsman, A., Skwarczynski, K., Smirnov, A., Smy, M., Sobczyk, J. T., Sobel, H., Soler, F. J. P., Sonoda, Y., Steinmann, J., Suvorov, S., Suzuki, A., Suzuki, S. Y., Suzuki, Y., Sztuc, A. A., Tada, M., Tajima, M., Takeda, A., Takeuchi, Y., Tanaka, H. K., Tanaka, H. A., Tanaka, S., Tanihara, Y., Tani, M., Teshima, N., Thompson, L. F., Toki, W., Touramanis, C., Towstego, T., Tsui, K. M., Tsukamoto, T., Tzanov, M., Uchida, Y., Vagins, M., Valder, S., Vallari, Z., Vargas, D., Vasseur, G., Vilela, C., Vinning, W. G. S., Vladisavljevic, T., Volkov, V. V., Wachala, T., Walker, J., Walsh, J. G., Wang, Y., Wark, D., Wascko, M. O., Weber, A., Wendell, R., Wilking, M. J., Wilkinson, C., Wilson, J. R., Wilson, R. J., Wood, K., Wret, C., Xia, J., Yamada, Y., Yamamoto, K., Yanagisawa, C., Yang, G., Yano, T., Yasutome, K., Yen, S., Yershov, N., Yokoyama, M., Yoshida, T., Yu, M., Zalewska, A., Zalipska, J., Zaremba, K., Zarnecki, G., Ziembicki, M., Zimmerman, E. D., Zito, M., Zsoldos, S., and Zykova, A.

Subjects
High Energy Physics - Experiment
Abstract

The electron (anti-)neutrino component of the T2K neutrino beam constitutes the largest background in the measurement of electron (anti-)neutrino appearance at the far detector. The electron neutrino scattering is measured directly with the T2K off-axis near detector, ND280. The selection of the electron (anti-)neutrino events in the plastic scintillator target from both neutrino and anti-neutrino mode beams is discussed in this paper. The flux integrated single differential charged-current inclusive electron (anti-)neutrino cross-sections, $d\sigma/dp$ and $d\sigma/d\cos(\theta)$, and the total cross-sections in a limited phase-space in momentum and scattering angle ($p > 300$ MeV/c and $\theta \leq 45^{\circ}$) are measured using a binned maximum likelihood fit and compared to the neutrino Monte Carlo generator predictions, resulting in good agreement.

Published
2020
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33. Correction: Kurniawan et al. Vapor-Phase Oxidant-Free Dehydrogenation of 2,3- and 1,4-Butanediol over Cu/SiO2 Catalyst Prepared by Crown-Ether-Assisted Impregnation. Chemistry 2023, 5, 406–421

Author

Enggah Kurniawan, Shuya Hosaka, Masayuki Kobata, Yasuhiro Yamada, and Satoshi Sato

Subjects
n/a, Chemistry, QD1-999
Abstract

In the published article “Vapor-Phase Oxidant-Free Dehydrogenation of 2,3- and 1,4-Butanediol over Cu/SiO2 Catalyst Prepared by Crown-Ether-Assisted Impregnation“ [...]

Published
2023
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34. Vapor-Phase Oxidant-Free Dehydrogenation of 2,3- and 1,4-Butanediol over Cu/SiO2 Catalyst Prepared by Crown-Ether-Assisted Impregnation

Author

Enggah Kurniawan, Shuya Hosaka, Masayuki Kobata, Yasuhiro Yamada, and Satoshi Sato

Subjects
organic additive, crown ether, Cu/SiO2 catalyst, butanediol dehydrogenation, Chemistry, QD1-999
Abstract

A silica-supported copper (Cu/SiO2) catalyst containing highly dispersed Cu nanoparticles was prepared via a crown-ether-assisted impregnation method. A 12-crown-4-ether-assisted Cu/SiO2 catalyst outperformed several Cu/SiO2 catalysts prepared with various organic additives in the dehydrogenation of 2,3- and 1,4-butanediol. It was found that the catalytic activity, i.e., the formation rate of acetoin from 2,3-butanediol and that of γ-butyrolactone from 1,4-butanediol, was proportional to the copper surface area.

Published
2023
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36. Association between blood urea nitrogen to creatinine ratio and neurologically favourable outcomes in out-of-hospital cardiac arrest in adults: A multicentre cohort study

Author

Nishioka, Norihiro, Kobayashi, Daisuke, Izawa, Junichi, Irisawa, Taro, Yamada, Tomoki, Yoshiya, Kazuhisa, Park, Changhwi, Nishimura, Tetsuro, Ishibe, Takuya, Kobata, Hitoshi, Kiguchi, Takeyuki, Kishimoto, Masafumi, Kim, Sung-Ho, Ito, Yusuke, Sogabe, Taku, Morooka, Takaya, Sakamoto, Haruko, Suzuki, Keitaro, Onoe, Atsunori, Matsuyama, Tasuku, Okada, Yohei, Matsui, Satoshi, Yoshimura, Satoshi, Kimata, Shunsuke, Kawai, Shunsuke, Makino, Yuto, Zha, Ling, Kiyohara, Kosuke, Kitamura, Tetsuhisa, and Iwami, Taku

Published
2023
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38. Diagnostic test accuracy of life-threatening electrocardiographic findings (ST-elevation myocardial infarction equivalents) for acute coronary syndrome after out-of-hospital cardiac arrest without ST-segment elevation

Author

Yoshimura, Satoshi, Kiguchi, Takeyuki, Irisawa, Taro, Yamada, Tomoki, Yoshiya, Kazuhisa, Park, Changhwi, Nishimura, Tetsuro, Ishibe, Takuya, Kobata, Hitoshi, Kishimoto, Masafumi, Kim, Sung-Ho, Ito, Yusuke, Sogabe, Taku, Morooka, Takaya, Sakamoto, Haruko, Suzuki, Keitaro, Onoe, Atsunori, Matsuyama, Tasuku, Matsui, Satoshi, Nishioka, Norihiro, Okada, Yohei, Makino, Yuto, Kimata, Shunsuke, Kawai, Shunsuke, Zha, Ling, Kiyohara, Kosuke, Kitamura, Tetsuhisa, and Iwami, Taku

Published
2023
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39. Manifestation of electron correlation effect in $\mathrm{U}~5f$ states of uranium compounds revealed by $\mathrm{U}~4d-5f$ resonant photoemission spectroscopy

Author

Fujimori, Shin-ichi, Kobata, Masaharu, Takeda, Yukiharu, Okane, Tetsuo, Saitoh, Yuji, Fujimori, Atsushi, Yamagami, Hiroshi, Haga, Yoshinori, Yamamoto, Etsuji, and Onuki, Yoshichika

Subjects
Condensed Matter - Strongly Correlated Electrons
Abstract

We have elucidated the nature of the electron correlation effect in uranium compounds by imaging the partial $\mathrm{U}~5f$ density of states (pDOS) of typical itinerant, localized, and heavy fermion uranium compounds by using the $\mathrm{U}~4d-5f$ resonant photoemission spectroscopy. Obtained $\mathrm{U}~5f$ pDOS exhibit a systematic trend depending on the physical properties of compounds. The coherent peak at the Fermi level can be described by the band-structure calculation, but an incoherent peak emerges on the higher binding energy side ($\lesssim 1~\mathrm{eV}$) in the \Uf pDOS of localized and heavy fermion compounds. As the $\mathrm{U}~5f$ state is more localized, the intensity of the incoherent peak is enhanced and its energy position is shifted to higher binding energy. These behaviors are consistent with the prediction of the Mott metal-insulator transition, suggesting that the Hubbard-$U$ type mechanism takes an essential role in the $5f$ electronic structure of actinide materials., Comment: Accepted to PRB Dec. 22, 2018

Published
2019
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41. External validation of the TiPS65 score for predicting good neurological outcomes in patients with out-of-hospital cardiac arrest treated with extracorporeal cardiopulmonary resuscitation

Author

Makino, Yuto, Okada, Yohei, Irisawa, Taro, Yamada, Tomoki, Yoshiya, Kazuhisa, Park, Changhwi, Nishimura, Tetsuro, Ishibe, Takuya, Kobata, Hitoshi, Kiguchi, Takeyuki, Kishimoto, Masafumi, Kim, Sung-Ho, Ito, Yusuke, Sogabe, Taku, Morooka, Takaya, Sakamoto, Haruko, Suzuki, Keitaro, Onoe, Atsunori, Matsuyama, Tasuku, Matsui, Satoshi, Nishioka, Norihiro, Yoshimura, Satoshi, Kimata, Shunsuke, Kawai, Shunsuke, Zha, Ling, Kiyohara, Kosuke, Kitamura, Tetsuhisa, and Iwami, Taku

Published
2023
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44. Carcinomas Gástricos com Hemorragia ou Perfuração: Uma Retrospecção com 44 casos

Author

Clóvis Massayuki Kobata, Nelson Yukitoshi Sato, Mário da Silva Monteiro, and Jesus Pan Chacon

Subjects
Carcinoma Gástrico, Carcinoma Gástrico Complicado, Carcinoma Gástrico Hemorrágico, Carcinoma Gástrico Perfurado, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Da análise retrospectiva de 44 doentes com carcinoma gástrico complicado com hemorragia e/ou perfuração, resultou a mortalidade global de 25,0% (11/44). Em sangramentos, a mortalidade em cirurgias realizadas em caráter de urgência foi de 27,3% e, em perfurações, de 44,4% O índice de ressecabilidade foi de 68,3% (gastrectomia total sete doentes; gastrectomia subtotal 21 doentes). A sobrevida, mesmo em doentes ressecados, tem-se mostrado semelhante à observada entre aqueles operados sem estas complicações.

Published
2023
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45. Clinical outcomes among out-of-hospital cardiac arrest patients treated by extracorporeal cardiopulmonary resuscitation: The CRITICAL study in Osaka

Author

Okada, Yohei, Irisawa, Taro, Yamada, Tomoki, Yoshiya, Kazuhisa, Park, Changhwi, Nishimura, Tetsuro, Ishibe, Takuya, Kobata, Hitoshi, Kiguchi, Takeyuki, Kishimoto, Masafumi, Kim, Sung-Ho, Ito, Yusuke, Sogabe, Taku, Morooka, Takaya, Sakamoto, Haruko, Suzuki, Keitaro, Onoe, Atsunori, Matsuyama, Tasuku, Kobayashi, Daisuke, Nishioka, Norihiro, Matsui, Satoshi, Yoshimura, Satoshi, Kimata, Shunsuke, Kawai, Shunsuke, Makino, Yuto, Kiyohara, Kosuke, Zha, Ling, Kitamura, Tetsuhisa, and Iwami, Taku

Published
2022
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46. Vanillin reduction in the biosynthetic pathway of capsiate, a non-pungent component of Capsicum fruits, is catalyzed by cinnamyl alcohol dehydrogenase

Author

Kaori Sano, Yuya Uzawa, Itsuki Kaneshima, Saika Nakasato, Masashi Hashimoto, Yoshiyuki Tanaka, Sachie Nakatani, and Kenji Kobata

Subjects
Medicine, Science
Abstract

Abstract Capsicum fruits synthesize capsaicin from vanillylamine, which is produced from vanillin in a reaction catalyzed by a putative aminotransferase (pAMT). Capsiate, a non-pungent compound that is structurally similar to capsaicin, is synthesized from vanillyl alcohol rather than vanillylamine. Vanillyl alcohol is possibly generated by the enzymatic reduction of vanillin, but the enzyme responsible for this reaction is unknown. In the present study, we revealed that the vanillin reductase in the capsiate biosynthetic pathway is cinnamyl alcohol dehydrogenase (CAD), which is an enzyme involved in lignin synthesis. The reduction of vanillin to vanillyl alcohol was greater in the mature red fruit placental extract than in the immature green fruit placental extract. This reduction was suppressed by both N-(O-hydroxyphenyl) sulfinamoyltertiobutyl acetate, a specific inhibitor of CAD, and ethylenediaminetetraacetic acid, a metalloenzyme inhibitor. The CaCAD1 transcript levels in the placenta were higher in the red fruits than in the green fruits. A recombinant CaCAD1 protein obtained using an Escherichia coli expression system reduced vanillin to vanillyl alcohol. This reaction was suppressed by the CAD inhibitors. These results strongly suggest that CAD is the enzyme that catalyzes the reduction of vanillin to vanillyl alcohol during capsiate biosynthesis. Syntenic analyses indicated that genes encoding CAD and capsaicin synthase (Pun1) involved in capsiate biosynthesis were acquired before the pAMT gene during the evolution of the family Solanaceae. This raises the possibility that in the genus Capsicum, the capsiate biosynthetic pathway emerged before the pAMT-encoding gene was acquired as the final trigger for capsaicin biosynthesis.

Published
2022
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47. Cardiac cephalalgia: a case series of four patients and updated literature review

Author

Hitoshi Kobata

Subjects
Cardiac cephalalgia, Cardiac cephalgia, Acute myocardial ischemia, Thunderclap headache, Neurological Emergency, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Abstract Background Cardiac damage is common in patients with acute brain injury; however, little is known regarding cardiac-induced neurological symptoms. In the International Classification of Headache, Third Edition (ICHD-III), cardiac cephalalgia is classified as a headache caused by impaired homeostasis. Methods This report presents four patients with acute myocardial infarction (AMI) who presented with headache that fulfilled the ICHD-III diagnostic criteria for cardiac cephalalgia. A systematic review of cardiac cephalalgia using the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines is also presented. Results Case 1: A 69-year-old man with a history of percutaneous coronary intervention (PCI) developed sudden severe occipital pain, nausea, and cold sweating. Coronary angiography (CAG) revealed occlusion of the right coronary artery (RCA). Case 2: A 66-year-old woman complained of increasing occipitalgia and chest discomfort while riding a bicycle. CAG demonstrated 99% stenosis of the left anterior descending artery. Case 3: A 54-year-old man presented with faintness, cold sweating, and occipitalgia after eating lunch. CAG detected occlusion of the RCA. Case 4: A 72-year-old man went into shock after complaining of a sudden severe headache and nausea. Vasopressors were initiated and emergency CAG was performed, which detected three-vessel disease. In all four, electrocardiography (ECG) showed ST segment elevation or depression and echocardiography revealed a left ventricular wall motion abnormality. All patients underwent PCI, which resulted in headache resolution after successful coronary reperfusion. A total of 59 cases of cardiac cephalalgia were reviewed, including the four reported here. Although the typical manifestation of cardiac cephalalgia is migraine-like pain on exertion, it may present with thunderclap headache without a trigger or chest symptoms, mimicking subarachnoid hemorrhage. ECG may not always show an abnormality. Headaches resolve after successful coronary reperfusion. Conclusions Cardiac cephalalgia resulting from AMI can present with or without chest discomfort and even mimic the classic thunderclap headache associated with SAH. It should be recognized as a neurological emergency and treated without delay.

Published
2022
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48. Benefits of Hypothermia for Young Patients with Acute Subdural Hematoma: A Computed Tomography Analysis of the Brain Hypothermia Study

Author

Hitoshi Kobata, Yasuhiro Kuroda, Eiichi Suehiro, Tadashi Kaneko, Motoki Fujita, Naofumi Bunya, Kei Miyata, Akihiko Inoue, Toru Hifumi, Yasutaka Oda, Kenji Dohi, Susumu Yamashita, Tsuyoshi Maekawa, and Collaboration group

Subjects
acute subdural hematoma, computed tomography, evacuated hematoma, hypothermia, targeted temperature management, traumatic brain injury, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9
Abstract

Therapeutic hypothermia for severe traumatic brain injury (TBI) has been repeatedly studied, but no past studies have assessed the detailed head computed tomography (CT) findings. We sought to investigate individual CT findings of severe TBI patients treated with targeted temperature management utilizing the head CT database obtained from the Brain Hypothermia study. Enrolled patients underwent either mild therapeutic hypothermia (32.0?C?34.0?C) or fever control (35.5?C?37.0?C). We assessed individual head CT images on arrival and after rewarming and investigated the correlations with outcomes. The initial CT data were available for 125 patients (hypothermia group?=?80, fever control group?=?45). Baseline characteristics and CT findings, such as hematoma thickness and midline shift, were similar in all aspects between the two groups. The favorable outcomes in the hypothermia and fever control groups were 38 (47.5%) and 24 (53.3%; p?=?0.53) for all 125 patients, respectively; 21 (46.7%) vs. 10 (38.5%; p?=?0.50) for 71 patients with acute subdural hematoma (SDH), respectively; and 12 (75.0%) vs. 4 (36.4%; p?=?0.045) in 27 young adults (?50 years) with acute SDH, respectively. There was a trend toward favorable outcomes for earlier time to reach 35.5?C (190 vs. 377?min, p?=?0.052) and surgery (155 vs. 180?min, p?=?0.096) in young patients with acute SDH. The second CT image revealed progression of the brain injury. This study demonstrated the potential benefits of early hypothermia in young patients with acute SDH, despite no difference in CT findings between the two groups. However, the small number of cases involved hindered the drawing of definitive conclusions. Future studies are warranted to validate the results.

Published
2022
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