1. Afamin and adropin in patients with alcohol-induced liver cirrhosis
- Author
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Andrzej Prystupa, Paweł Kiciński, Dorota Luchowska-Kocot, Jarosław Sak, Tomasz Prystupa, Ko-Hsin Chen, Yu-Chieh Chen, Lech Panasiuk, and Wojciech Załuska
- Subjects
alcoholic liver cirrhosis ,Adropin ,Child-Pugh score ,afamin ,Agriculture ,Environmental sciences ,GE1-350 - Abstract
The aim of the study was to determine serum concentrations of afamin and adropin in patients with alcoholic liver cirrhosis and to define their correlation with the stage of disease. The study included 99 patients with alcoholic cirrhosis from the region of Lublin, (Eastern Poland). Liver cirrhosis was diagnosed based on clinical features, history of heavy alcohol consumption, laboratory tests and abdominal ultrasonography. The control group consisted of 20 healthy individuals without liver disease who did not abuse alcohol. The serum afamin and adropin concentrations were determined using ELISA kits. The concentration of afamin was found to be significantly lower in patients with compensated alcoholic liver cirrhosis, i.e. P-Ch B (85.1±40.6 μg/ml) and P-Ch C (56.4±32.3 μg/ml) individuals, compared to the control group (135.9±43.6 μg/ml); p-value was
- Published
- 2018
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