46 results on '"Ko, Soo S."'
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2. Assessment of inhibitor structure-activity relationship and cholesterol biosynthesis inhibition properties
3. Use of a Conformational-Switching Mechanism to Modulate Exposed Polarity: Discovery of CCR2 Antagonist BMS-741672
4. Synthesis and evaluation of analogs of Efavirenz (SUSTIVA TM) as HIV-1 reverse transcriptase inhibitors
5. Synthesis and evaluation of benzoxazinones as HIV-1 reverse transcriptase inhibitors. Analogs of Efavirenz (SUSTIVA TM)
6. Unsymmetrical cyclic ureas as HIV-1 protease inhibitors: Novel biaryl indazoles as P2/P2′ substituents
7. Identification of Tricyclic Agonists of Sphingosine-1-phosphate Receptor 1 (S1P1) Employing Ligand-Based Drug Design
8. Discovery of a Potent and Orally Bioavailable Dual Antagonist of CC Chemokine Receptors 2 and 5
9. Identification of Tricyclic Agonists of Sphingosine-1-phosphate Receptor 1 (S1P1) Employing Ligand-Based Drug Design.
10. From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part II: Acyclic replacements for the (3 S)-3-benzylpiperidine in a series of potent CCR3 antagonists
11. From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part I: The discovery of CCR3 antagonist development candidate BMS-639623 with picomolar inhibition potency against eosinophil chemotaxis
12. ChemInform Abstract: Synthesis and Evaluation of Benzoxazinones as HIV-1 Reverse Transcriptase Inhibitors. Analogues of Efavirenz (Sustiva).
13. ChemInform Abstract: Unsymmetrical Cyclic Ureas as HIV-1 Protease Inhibitors: Novel Biaryl Indazoles as P2/P2′ Substituents.
14. ChemInform Abstract: Novel 2,2-Dioxide-4,4-disubstituted-1,3-H-2,1,3-benzothiadiazines as Non-Nucleoside Reverse Transcriptase Inhibitors.
15. ChemInform Abstract: Synthesis and Evaluation of Efavirenz (Sustiva) Analogues as HIV-1 Reverse Transcriptase Inhibitors: Replacement of the Cyclopropylacetylene Side Chain.
16. Enantioselective Synthesis of Benzyl (1S,2R,4R)-4-(tert-Butoxycarbonylamino)-2-(hydroxymethyl)cyclohexylcarbamate Using an Iodolactamization As the Key Step
17. CC chemokine receptor-3 (CCR3) antagonists: Improving the selectivity of DPC168 by reducing central ring lipophilicity
18. From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part II: Acyclic replacements for the (3S)-3-benzylpiperidine in a series of potent CCR3 antagonists
19. 2,4-Disubstituted piperidines as selective CC chemokine receptor 3 (CCR3) antagonists: Synthesis and selectivity
20. Selective Inhibition of Eosinophil Influx into the Lung by Small Molecule CC Chemokine Receptor 3 Antagonists in Mouse Models of Allergic Inflammation
21. Discovery of CC Chemokine Receptor-3 (CCR3) Antagonists with Picomolar Potency
22. Discovery of N-propylurea 3-benzylpiperidines as selective CC chemokine receptor-3 (CCR3) antagonists
23. Discovery and Structure−Activity Relationship of N-(Ureidoalkyl)-Benzyl-Piperidines As Potent Small Molecule CC Chemokine Receptor-3 (CCR3) Antagonists
24. CCR3 antagonists: a potential new therapy for the treatment of asthma. Discovery and structure–activity relationships
25. 4,1-Benzoxazepinone analogues of efavirenz (Sustiva™) as HIV-1 reverse transcriptase inhibitors
26. Synthesis and Evaluation of Efavirenz (SustivaTM) Analogues as HIV-1 Reverse Transcriptase Inhibitors: Replacement of the Cyclopropylacetylene Side Chain
27. Inhibition of Clinically Relevant Mutant Variants of HIV-1 by Quinazolinone Non-Nucleoside Reverse Transcriptase Inhibitors
28. Novel 2,2-dioxide-4,4-disubstituted-1,3- H -2,1,3-benzothiadiazines as non-nucleoside reverse transcriptase inhibitors
29. Expanded-Spectrum Nonnucleoside Reverse Transcriptase Inhibitors Inhibit Clinically Relevant Mutant Variants of Human Immunodeficiency Virus Type 1
30. Synthesis and evaluation of analogs of Efavirenz (SUSTIVATM) as HIV-1 reverse transcriptase inhibitors
31. Design and selection of DMP 850 and DMP 851: the next generation of cyclic urea HIV protease inhibitors
32. Effects of 15-Oxa-32-vinyl-lanost-8-ene-3β,32 diol on the Expression of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Low Density Lipoprotein Receptor in Rat Liver
33. Nonsymmetric P2/P2‘ Cyclic Urea HIV Protease Inhibitors. Structure−Activity Relationship, Bioavailability, and Resistance Profile of Monoindazole-Substituted P2 Analogues
34. ACAT inhibitors derived from hetero-Diels-Alder cycloadducts of thioaldehydes
35. Substrate-based inhibitors of lanosterol 14.alpha.-methyl demethylase: II. Time-dependent enzyme inactivation by selected oxylanosterol analogs
36. Substrate-based inhibitors of lanosterol 14.alpha.-methyl demethylase: I. Assessment of inhibitor structure-activity relationship and cholesterol biosynthesis inhibition properties
37. Synthesis and Evaluation of Efavirenz (Sustiva TM) Analogues as HIV-1 Reverse Transcriptase Inhibitors: Replacement of the Cyclopropylacetylene Side Chain
38. Substrate based inhibitors of lanosterol 14 alpha- methyl demethylase: I. Assessment of inhibitor...
39. Enentioselective Synthesis of Benzyl (1S,2R,4R)-4-(tert-Butoxycarbonylamino)-2-(hydroxymethyl)-cyclohexylcarbamate Using an Iodolactamization As the Key Step.
40. Design and synthesis of potential DNA cross-linking reagents based on the anthramycin class of minor groove binding compounds
41. The intramolecular nitrile oxide-olefin [3+2] cycloaddition route to the maytansinoids
42. ChemInform Abstract: Synthesis and Evaluation of Efavirenz (Sustiva) Analogues as HIV-1 Reverse Transcriptase Inhibitors: Replacement of the Cyclopropylacetylene Side Chain.
43. ChemInform Abstract: Novel 2,2-Dioxide-4,4-disubstituted-1,3-H-2,1,3-benzothiadiazines as Non-Nucleoside Reverse Transcriptase Inhibitors.
44. ChemInform Abstract: Synthesis and Evaluation of Benzoxazinones as HIV-1 Reverse Transcriptase Inhibitors. Analogues of Efavirenz (Sustiva).
45. ChemInform Abstract: Unsymmetrical Cyclic Ureas as HIV-1 Protease Inhibitors: Novel Biaryl Indazoles as P2/P2′ Substituents.
46. Discovery and structure-activity relationship of N-(ureidoalkyl)-benzyl-piperidines as potent small molecule CC chemokine receptor-3 (CCR3) antagonists.
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