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186 results on '"Knutson, Kristine"'

1. Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome

Author

Walitt, Brian, Singh, Komudi, LaMunion, Samuel R., Hallett, Mark, Jacobson, Steve, Chen, Kong, Enose-Akahata, Yoshimi, Apps, Richard, Barb, Jennifer J., Bedard, Patrick, Brychta, Robert J., Buckley, Ashura Williams, Burbelo, Peter D., Calco, Brice, Cathay, Brianna, Chen, Li, Chigurupati, Snigdha, Chen, Jinguo, Cheung, Foo, Chin, Lisa M. K., Coleman, Benjamin W., Courville, Amber B., Deming, Madeleine S., Drinkard, Bart, Feng, Li Rebekah, Ferrucci, Luigi, Gabel, Scott A., Gavin, Angelique, Goldstein, David S., Hassanzadeh, Shahin, Horan, Sean C., Horovitz, Silvina G., Johnson, Kory R., Govan, Anita Jones, Knutson, Kristine M., Kreskow, Joy D., Levin, Mark, Lyons, Jonathan J., Madian, Nicholas, Malik, Nasir, Mammen, Andrew L., McCulloch, John A., McGurrin, Patrick M., Milner, Joshua D., Moaddel, Ruin, Mueller, Geoffrey A., Mukherjee, Amrita, Muñoz-Braceras, Sandra, Norato, Gina, Pak, Katherine, Pinal-Fernandez, Iago, Popa, Traian, Reoma, Lauren B., Sack, Michael N., Safavi, Farinaz, Saligan, Leorey N., Sellers, Brian A., Sinclair, Stephen, Smith, Bryan, Snow, Joseph, Solin, Stacey, Stussman, Barbara J., Trinchieri, Giorgio, Turner, Sara A., Vetter, C. Stephenie, Vial, Felipe, Vizioli, Carlotta, Williams, Ashley, Yang, Shanna B., and Nath, Avindra

Published
2024
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8. The University of Michigan Dioxin Exposure Study: Predictors of Human Serum Dioxin Concentrations in Midland and Saginaw, Michigan

Author

Garabrant, David H., Franzblau, Alfred, Lepkowski, James, Gillespie, Brenda W., Adriaens, Peter, Demond, Avery, Hedgeman, Elizabeth, Knutson, Kristine, Zwica, Lynn, Olson, Kristen, Towey, Timothy, Chen, Qixuan, Hong, Biling, Chang, Chiung-Wen, Lee, Shih-Yuan, Ward, Barbara, LaDronka, Kathy, Luksemburg, William, and Maier, Martha

Published
2009
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12. Resting-State Correlations of Fatigue Following Military Deployment

Author

Lewis, Jeffrey D., primary, Knutson, Kristine M., additional, Gotts, Stephen J., additional, Tierney, Michael, additional, Ramage, Amy, additional, Tate, David F., additional, Clauw, Daniel, additional, Williams, David A., additional, Robin, Donald A., additional, and Wassermann, Eric M., additional

Published
2021
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28. Preface

Author

Anderson, James M., primary, Kim, Sung Wan, additional, Kopeˆek, Jindrich, additional, and Knutson, Kristine, additional

Published
1994
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33. Theory of mind impairment in patients with behavioural variant fronto-temporal dementia (bv-FTD) increases caregiver burden

Author

Brioschi Guevara, Andrea, Knutson, Kristine M., Wassermann, Eric M., Pulaski, Sarah, Grafman, Jordan, Krueger, Frank, Brioschi Guevara, Andrea, Knutson, Kristine M., Wassermann, Eric M., Pulaski, Sarah, Grafman, Jordan, and Krueger, Frank

Abstract

Background: Theory of mind (ToM), the capacity to infer the intention, beliefs and emotional states of others, is frequently impaired in behavioural variant fronto-temporal dementia patients (bv-FTDp); however, its impact on caregiver burden is unexplored. Setting: National Institute of Neurological Disorders and Stroke, National Institutes of Health. Subjects: bv-FTDp (n = 28), a subgroup of their caregivers (n = 20) and healthy controls (n = 32). Methods: we applied a faux-pas (FP) task as a ToM measure in bv-FTDp and healthy controls and the Zarit Burden Interview as a measure of burden in patients' caregivers. Patients underwent structural MRI; we used voxel-based morphometry to examine relationships between regional atrophy and ToM impairment and caregiver burden. Results: FP task performance was impaired in bv-FTDp and negatively associated with caregiver burden. Atrophy was found in areas involved in ToM. Caregiver burden increased with greater atrophy in left lateral premotor cortex, a region associated in animal models with the presence of mirror neurons, possibly involved in empathy. Conclusion: ToM impairment in bv-FTDp is associated with increased caregiver burden

Published
2017

41. Effective connectivity of brain regions underlying third-party punishment: Functional MRI and Granger causality evidence.

Author

Bellucci, Gabriele, Chernyak, Sergey, Hoffman, Morris, Deshpande, Gopikrishna, Dal Monte, Olga, Knutson, Kristine M., Grafman, Jordan, and Krueger, Frank

Subjects
PUNISHMENT, GRANGER causality test, LEGAL liability, VIOLATION of sovereignty, MAGNETIC resonance imaging of the brain, PSYCHOLOGY
Abstract

Third-party punishment (TPP) for norm violations is an essential deterrent in large-scale human societies, and builds on two essential cognitive functions: evaluating legal responsibility and determining appropriate punishment. Despite converging evidence that TPP is mediated by a specific set of brain regions, little is known about their effective connectivity (direction and strength of connections). Applying parametric event-related functional MRI in conjunction with multivariate Granger causality analysis, we asked healthy participants to estimate how much punishment a hypothetical perpetrator deserves for intentionally committing criminal offenses varying in levels of harm. Our results confirmed that TPP legal decisions are based on two domain-general networks: the mentalizing network for evaluating legal responsibility and the central-executive network for determining appropriate punishment. Further, temporal pole (TP) and dorsomedial prefrontal cortex (PFC) emerged as hubs of the mentalizing network, uniquely generating converging output connections to ventromedial PFC, temporo-parietal junction, and posterior cingulate. In particular, dorsomedial PFC received inputs only from TP and both its activation and its connectivity to dorsolateral PFC correlated with degree of punishment. This supports the hypothesis that dorsomedial PFC acts as the driver of the TPP activation pattern, leading to the decision on the appropriate punishment. In conclusion, these results advance our understanding of the organizational elements of the TPP brain networks and provide better insights into the mental states of judges and jurors tasked with blaming and punishing legal wrongs. [ABSTRACT FROM PUBLISHER]

Published
2017
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44. Relationship between polychlorinated dibenzo- p -dioxin, polychlorinated dibenzofuran, and dioxin-like polychlorinated biphenyl concentrations in vegetation and soil on residential properties

Author

Department of Civil and Environmental Engineering, University of Michigan College of Engineering, Ann Arbor, Michigan 48109, USA ; Department of Civil and Environmental Engineering, University of Michigan College of Engineering, Ann Arbor, Michigan 48109, USA., Department of Civil and Environmental Engineering, University of Michigan College of Engineering, Ann Arbor, Michigan 48109, USA, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA, Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan, USA, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA, LimnoTech, Ann Arbor, Michigan, USA, Vista Analytical Laboratory, El Dorado Hills, California, USA, Demond, Avery, Towey, Timothy, Adriaens, Peter, Zhong, Xiaobo, Knutson, Kristine, Chen, Qixuan, Hong, Biling, Gillespie, Brenda, Franzblau, Alfred, Garabrant, David, Lepkowski, James, Luksemburg, William, Maier, Martha, Department of Civil and Environmental Engineering, University of Michigan College of Engineering, Ann Arbor, Michigan 48109, USA ; Department of Civil and Environmental Engineering, University of Michigan College of Engineering, Ann Arbor, Michigan 48109, USA., Department of Civil and Environmental Engineering, University of Michigan College of Engineering, Ann Arbor, Michigan 48109, USA, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, USA, Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan, USA, Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA, LimnoTech, Ann Arbor, Michigan, USA, Vista Analytical Laboratory, El Dorado Hills, California, USA, Demond, Avery, Towey, Timothy, Adriaens, Peter, Zhong, Xiaobo, Knutson, Kristine, Chen, Qixuan, Hong, Biling, Gillespie, Brenda, Franzblau, Alfred, Garabrant, David, Lepkowski, James, Luksemburg, William, and Maier, Martha

Abstract

The University of Michigan Dioxin Exposure Study was undertaken to address concerns that the industrial discharge of dioxin-like compounds in the Midland, Michigan, USA area had resulted in the contamination of soil and vegetation in the Tittabawassee River floodplain and downwind of the incinerator in the City of Midland. The study included the analysis of 597 vegetation samples, predominantly grass and weeds, from residential properties selected through a multistage probabilistic sample design in the Midland area, and in Jackson and Calhoun Counties (Michigan), as a background comparison, for 29 polychlorinated dibenzo- p -dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs). The mean toxic equivalent (TEQ) of the house perimeter vegetation samples ranged from 4.2 to 377???pg/g. The ratio of TEQs (vegetation to soil) was about 0.3, with a maximum of 3.5. Based on a calculation of the similarity of the congener patterns between the soil and the vegetation, it appeared that the source of the contamination on the vegetation was the surrounding soil. This conclusion was supported by linear regression analysis, which showed that the largest contributor to the R 2 for the outcome variable of log 10 of the vegetation concentration was log 10 of the surrounding soil concentration. Models of vegetation contamination usually focus on atmospheric deposition and partitioning. The results obtained here suggest that the deposition of soil particles onto vegetation is a significant route of contamination for residential herbage. Thus, the inclusion of deposition of soil particles onto vegetation is critical to the accurate modeling of contamination residential herbage in communities impacted by historic industrial discharges of persistent organic compounds. Environ. Toxicol. Chem. 2010;29:2660???2668. ?? 2010 SETAC

Published
2010

45. Estimation of age- and sex-specific background human serum concentrations of PCDDs, PCDFs, and PCBs in the UMDES and NHANES populations

Author

Chen, Qixuan, primary, Jiang, Xiaohui, additional, Hedgeman, Elizabeth, additional, Knutson, Kristine, additional, Gillespie, Brenda, additional, Hong, Biling, additional, Lepkowski, James M., additional, Franzblau, Alfred, additional, Jolliet, Olivier, additional, Adriaens, Peter, additional, Demond, Avery H., additional, and Garabrant, David H., additional

Published
2013
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47. Association Between Traumatic Brain Injury-Related Brain Lesions and Long-term Caregiver Burden.

Author

Brioschi Guevara, Andrea, Demonet, Jean-Francois, Polejaeva, Elena, Knutson, Kristine M., Wassermann, Eric M., Grafman, Jordan, and Krueger, Frank

Abstract

Objective: To investigate the association between traumatic brain injury (TBI)-related brain lesions and long-term caregiver burden in relation to dysexecutive syndrome. Setting: National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland. Participants: A total of 256 participants: 105 combat veterans with TBI, 23 healthy control combat veterans (HCv), and 128 caregivers. Outcome Measure: Caregiver burden assessed by the Zarit Burden Interview at 40 years postinjury. Design: Participants with penetrating TBI were compared with HCv on perceived caregiver burden and neuropsychological assessment measures. Data of computed tomographic scans (overlay lesion maps of participants with a penetrating TBI whose caregivers have a significantly high burden) and behavioral statistical analyses were combined to identify brain lesions associated with caregiver burden. Results: Burden was greater in caregivers of veterans with TBI than in caregivers of HCv. Caregivers of participants with lesions affecting cognitive and behavioral indicators of dysexecutive syndrome (ie, left dorsolateral prefrontal cortex and dorsal anterior cingulate cortex) showed greater long-term burden than caregivers of participants with lesions elsewhere in the brain. Conclusion and Implication: The TBI-related brain lesions have a lasting effect on long-term caregiver burden due to cognitive and behavioral factors associated with dysexecutive syndrome [ABSTRACT FROM AUTHOR]

Published
2016
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49. Relationship between polychlorinated dibenzo-p-dioxin, polychlorinated dibenzofuran, and dioxin-like polychlorinated biphenyl concentrations in vegetation and soil on residential properties

Author

Demond, Avery, primary, Towey, Timothy, additional, Adriaens, Peter, additional, Zhong, Xiaobo, additional, Knutson, Kristine, additional, Chen, Qixuan, additional, Hong, Biling, additional, Gillespie, Brenda, additional, Franzblau, Alfred, additional, Garabrant, David, additional, Lepkowski, James, additional, Luksemburg, William, additional, and Maier, Martha, additional

Published
2010
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