489 results on '"Knollmann, Bjorn C."'
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2. Triiodothyronine and dexamethasone alter potassium channel expression and promote electrophysiological maturation of human-induced pluripotent stem cell-derived cardiomyocytes
3. RyR2 inhibition with dantrolene is antiarrhythmic, prevents further pathological remodeling, and improves cardiac function in chronic ischemic heart disease
4. Regulation of Postnatal Cardiomyocyte Maturation by an RNA Splicing Regulator RBFox1
5. The proteostasis interactomes of trafficking-deficient variants of the voltage-gated potassium channel KV11.1 associated with Long QT Syndrome
6. Low expression of the K280N TNNT2 mutation is sufficient to increase basal myofilament activation in human hypertrophy cardiomyopathy
7. Backbone-Determined Antiarrhythmic Structure–Activity Relationships for a Mirror Image, Oligomeric Depsipeptide Natural Product.
8. The proteostasis interactomes of trafficking-deficient KV11.1 variants associated with Long QT Syndrome and pharmacological chaperone rescue
9. ent-Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic inCasq2−/−Mice
10. Hypertrophic cardiomyopathy dysfunction mimicked in human engineered heart tissue and improved by SGLT2 inhibitors
11. Abstract 13523: The Role of Mitochondrial-Associated-Membranes in Ca-Dependent Arrhythmias
12. Abstract 13377: Modulating Mitochondrial Phosphate Transport Shapes Intracellular Ca Signaling to Impact Arrhythmogenesis
13. High-throughput discovery of trafficking-deficient variants in the cardiac potassium channel KV11.1
14. MCL-1 Inhibition by Selective BH3 Mimetics Disrupts Mitochondrial Dynamics Causing Loss of Viability and Functionality of Human Cardiomyocytes
15. Ryanodine receptor 2 inhibition reduces dispersion of cardiac repolarization, improves contractile function, and prevents sudden arrhythmic death in failing hearts
16. Author Response: Ryanodine receptor 2 inhibition reduces dispersion of cardiac repolarization, improves contractile function, and prevents sudden arrhythmic death in failing hearts
17. Ryanodine receptor inhibition with acute dantrolene treatment reduces arrhythmia susceptibility in human hearts
18. Unnatural verticilide enantiomer inhibits type 2 ryanodine receptor-mediated calcium leak and is antiarrhythmic
19. Buffering the Heart Against Atrial Fibrillation.
20. Patient-independent human induced pluripotent stem cell model: A new tool for rapid determination of genetic variant pathogenicity in long QT syndrome
21. Hypertrophic cardiomyopathy dysfunction mimicked in human engineered heart tissue and improved by sodium–glucose cotransporter 2 inhibitors.
22. Danicamtiv Recruits Myosin Motors to Aid the Failing Heart
23. Ryanodine receptor 2 inhibition improves cardiac repolarization reserve and contractile function and prevents sudden arrhythmic death in failing hearts
24. ent-Verticilide B1 inhibits type 2 ryanodine receptor channels and is antiarrhythmic in Casq2-/- mice
25. Hypertrophic cardiomyopathy-linked mutation in troponin T causes myofibrillar disarray and pro-arrhythmic action potential changes in human iPSC cardiomyocytes
26. Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function
27. PO-02-176 MODIFICATION OF HUMAN STEM CELL-DERIVED CARDIOMYOCYTES ELECTROPHYSIOLOGY FOR CARDIAC REGENERATION
28. PO-01-173 IBRUTINIB TREATMENT RESULTS IN INCREASED PHOSPHORYLATION OF THE ERK1/2 SIGNALING PATHWAY IN ATRIAL-SPECIFIC HUMAN IPSC-DERIVED CARDIOMYOCYTES (HIPSC-ACMS)
29. Cellular and electrophysiological characterization of triadin knockout syndrome using induced pluripotent stem cell-derived cardiomyocytes
30. Supplementary data from Inhibition of the Biosynthesis of Prostaglandin E2 By Low-Dose Aspirin: Implications for Adenocarcinoma Metastasis
31. Data from A Genetic Mouse Model Recapitulates Immune Checkpoint Inhibitor–Associated Myocarditis and Supports a Mechanism-Based Therapeutic Intervention
32. Data from Inhibition of the Biosynthesis of Prostaglandin E2 By Low-Dose Aspirin: Implications for Adenocarcinoma Metastasis
33. Supplementary Data from A Genetic Mouse Model Recapitulates Immune Checkpoint Inhibitor–Associated Myocarditis and Supports a Mechanism-Based Therapeutic Intervention
34. Supplementary Figures from Inhibition of the Biosynthesis of Prostaglandin E2 By Low-Dose Aspirin: Implications for Adenocarcinoma Metastasis
35. Abstract 15420: Resolving a Controversy: Inhibition of Cardiac Ryanodine Receptors is the Principal Mechanism of Antiarrhythmic Action of Flecainide in Catecholaminergic Polymorphic Ventricular Tachycardia
36. Regulation of Postnatal Cardiomyocyte Maturation by an RNA Splicing Regulator RBFox1.
37. Cardiomyocyte Homeodomain-Interacting Protein Kinase 2 Maintains Basal Cardiac Function via Extracellular Signal-Regulated Kinase Signaling
38. In Vivo Pharmacokinetic and Pharmacodynamic Properties of the Antiarrhythmic Moleculeent-Verticilide
39. Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization
40. Modulating mitochondrial phosphate transport shapes intracellular Ca signaling to impact arrhythmogenesis
41. Dissecting the mechanisms by which a pathogenic variant in cardiac TnT tail domain leads to disturbed myofilament performance
42. HCM and DCM associated TNNT2 sarcomeric variants induce nucleus remodeling in human iPSC-CMs
43. The role of mitochondrial-associated-membranes in Ca-dependent arrhythmias
44. Abnormal kinetics of contraction caused by an α-actinin 2 missense variant in the EF-3-4 hand domain in human myocardium
45. Neuronal Na+ Channels Are Integral Components of Pro-Arrhythmic Na+/Ca2+ Signaling Nanodomain That Promotes Cardiac Arrhythmias During β-Adrenergic Stimulation
46. Androgenic Effects on Ventricular Repolarization: A Translational Study From the International Pharmacovigilance Database to iPSC-Cardiomyocytes
47. Studying Long QT Syndrome Caused by NAA10Genetic Variants Using Patient-Derived Induced Pluripotent Stem Cells
48. Impaired calcium-calmodulin-dependent inactivation of Cav1.2 contributes to loss of sarcoplasmic reticulum calcium release refractoriness in mice lacking calsequestrin 2
49. Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals
50. Structure–Activity Relationships for the N-Me- Versus N-H-Amide Modification to Macrocyclic ent-Verticilide Antiarrhythmics
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