91 results on '"Knežević Đ"'
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2. Shell Inhomogeneities of the Single-Particle Level Spectra in the Practical Model of the Gamma-Decay of Neutron Resonance
- Author
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Jovančević, N., Mitsyna, L. V., Sukhovoj, A. M., Knežević, D., Krmar, M., Petrović, J., Oberstedt, S., Dragić, A., Hambsch, F. -J., and Vu, D. C.
- Subjects
Nuclear Experiment - Abstract
In this paper we have taken into account shell inhomogeneities of the single-particle level spectra in the practical model of the gamma-decay of neutron resonance developed in Dubna. The obtained data confirm a dependence of breaking thresholds for Cooper pairs on a shape of investigated nuclei - a phenomenon noticed earlier without taking into account the shell inhomogeneity.
- Published
- 2018
3. Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study
- Author
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Glasbey, James, Ademuyiwa, Adesoji, Adisa, Adewale, AlAmeer, Ehab, Arnaud, Alexis P, Ayasra, Faris, Azevedo, José, Minaya-Bravo, Ana, Costas-Chavarri, Ainhoa, Edwards, John, Elhadi, Muhammed, Fiore, Marco, Fotopoulou, Christina, Gallo, Gaetano, Ghosh, Dhruva, Griffiths, Ewen A, Harrison, Ewen, Hutchinson, Peter, Lawani, Ismail, Lawday, Samuel, Lederhuber, Hans, Leventoglu, Sezai, Li, Elizabeth, Gomes, Gustavo Mendonça Ataíde, Mann, Harvinder, Marson, Ella J, Martin, Janet, Mazingi, Dennis, McLean, Kenneth, Modolo, Maria, Moore, Rachel, Morton, Dion, Ntirenganya, Faustin, Pata, Francesco, Picciochi, Maria, Pockney, Peter, Ramos-De la Medina, Antonio, Roberts, Keith, Roslani, April Camilla, Kottayasamy Seenivasagam, Rajkumar, Shaw, Richard, Simões, Joana Filipa Ferreira, Smart, Neil, Stewart, Grant D, Sullivan, Richard, Sundar, Sudha, Tabiri, Stephen, Taylor, Elliott H, Vidya, Raghavan, Nepogodiev, Dmitri, Bhangu, Aneel, Glasbey, James C, Bhangu, Aneel A, Siaw-Acheampong, Kwabena, Benson, Ruth A, Bywater, Edward, Chaudhry, Daoud, Dawson, Brett E, Evans, Jonathan P, Gujjuri, Rohan R, Heritage, Emily, Jones, Conor S, Kamarajah, Sivesh K, Khatri, Chetan, Khaw, Rachel A, Keatley, James M, Knight, Andrew, Mann, Harvinder S, McLean, Kenneth A, Mckay, Siobhan C, Mills, Emily C, Pellino, Gianluca, Tiwari, Abhinav, Simoes, Joana FF, Trout, Isobel M, Venn, Mary L, Wilkin, Richard JW, Smart, Neil J, Moug, Susan, Di Saverio, Salomone, Vallance, Abigail, Vimalchandran, Dale, Evans, Richard PT, Townend, Philip, McKay, Siobhan, Isaac, John, Satoi, Sohei, Coonar, Aman S, Marchbank, Adrian, Caruana, Edward J, Layton, Georgia R, Patel, Akshay, Brunelli, Alessandro, Ford, Samuel, Desai, Anant, Gronchi, Alessandro, Almond, Max, Tirotta, Fabio, Dumitra, Sinziana, Kolias, Angelos, Price, Stephen J, Fountain, Daniel M, Jenkinson, Michael D, Marcus, Hani J, Piper, Rory J, Lippa, Laura, Servadei, Franco, Esene, Ignatius, Freyschlag, Christian, Neville, Iuri, Rosseau, Gail, Schaller, Karl, Demetriades, Andreas K, Robertson, Faith, Alamri, Alex, Schache, Andrew G, Winter, Stuart C, Ho, Michael, Nankivell, Paul, Rey Biel, Juan, Batstone, Martin, Ganly, Ian, Wilkins, Alex, Singh, Jagdeep K, Thekinkattil, Dinesh, Leung, Elaine YL, Khan, Tabassum, Chiva, Luis, Sehouli, Jalid, Fagotti, Anna, Cohen, Paul, Gutelkin, Murat, Ghebre, Rahel, Konney, Thomas, Pareja, Rene, Bristow, Rob, Dowdy, Sean, Shylasree, TS, Ng, Joe, Fujiwara, Keiichi, Lamb, Benjamin, Narahari, Krishna, McNeill, Alan, Colquhoun, Alexandra, McGrath, John S, Bromage, Steve, Barod, Ravi, Kasivisvanathan, Veeru, Klatte, Tobias, Abbott, Tom EF, Abukhalaf, Sadi, Adamina, Michel, Ademuyiwa, Adesoji O, Agarwal, Arnav, Akkulak, Murat, Alameer, Ehab, Alderson, Derek, Alakaloko, Felix, Albertsmeier, Markus, Alser, Osaid, Alshaar, Muhammad, Alshryda, Sattar, Augestad, Knut Magne, Bankhead-Kendall, Brittany K, Barlow, Emma, Beard, David, Blanco-Colino, Ruth, Brar, Amanpreet, Breen, Kerry A, Bretherton, Chris, Buarque, 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Griffiths, B, Gananadha, S, McLaren, M, Cecire, J, Joshi, N, Salindera, S, Sutherland, A, Ahn, JH, Charlton, G, Chen, S, Gauri, N, Hayhurst, R, Jang, S, Jia, F, Mulligan, C, Yang, W, Ye, G, Zhang, H, Ballal, M, Gibson, D, Hayne, D, McMillan, H, Moss, J, Pugliese, MJ, Richards, T, Seow, YTN, Thian, A, Viswambaram, P, Vo, UG, Bennetts, J, Bright, T, Brooke-Smith, M, Fong, R, Gricks, B, Huang, L, Lam, YH, Nathan, A, Ong, BS, Ooi, E, Szpytma, M, Watson, D, Bagraith, K, Caird, S, Chan, E, Dawson, C, Ho, D, Hui, N, Izwan, S, Jeyarajan, E, Jordan, S, Liang, R, Lim, A, Nolan, GJ, Oar, A, Parker, D, Puhalla, H, Quennell, A, Rutherford, L, Sommerville, C, Townend, P, Von Papen, M, Wullschleger, M, Dawson, AC, Drane, A, Blatt, A, Cope, D, Egoroff, N, Fenton, M, Gani, J, Lott, N, Pockney, P, Shugg, N, Elliott, M, Phung, D, Phan, D, Townend, D, Bong, C, Gundara, J, Frankel, A, Bowman, S, Guerra, GR, Gerns, N, McGeorge, S, Riddell, A, Roberts, M, Rukin, N, Bolt, J, Buddingh, K, Dudi-Venkata, NN, 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Ali, A, M.elghazaly, S, Mohammed, MM, Monib, FA, Nageh, MA, Saad, A, Saad, MM, Shahine, M, Yousof, EA, Youssef, A, El-Deeb, M, Fawzy, M, Ghaly, G, Ibraheem, M, Eldaly, A, Esmail, E, ElFiky, M, Nabil, A, Alrahawy, M, Sakr, A, Soliman, H, Soltan, H, Amira, G, Sallam, I, Sherief, M, Sherif, A, Abdelrahman, A, Aboulkassem, H, Hamdy, R, Morsi, A, Sherif, G, Abdeldayem, H, Abdelkader Salama, I, Balabel, M, Fayed, Y, Sherif, AE, Elmorsi, R, Emile, S, Refky, B, Abd-elsalam, S, Badr, H, Elbahnasawy, M, Elzoghby, M, Essa, M, Gamal Badr, S, Ghoneim, A, Hamad, O, Hamada, M, Hammad, M, Hawila, A, Morsy, MS, Salman, S, Sarsik, S, Bekele, K, Kauppila, JH, Sarjanoja, E, Helminen, O, Huhta, H, Beyrne, C, Jouffret, L, Lugans, L, Marie-Macron, L, Chouillard, E, De Simone, B, Fredon, F, Roux, A, Bettoni, J, Dakpé, S, Devauchelle, B, Lavagen, N, Testelin, S, Boucher, S, Breheret, R, Gueutier, A, Kahn, A, Kün-Darbois, J, Barrabe, A, Lakkis, Z, Louvrier, A, Manfredelli, S, Mathieu, P, Chebaro, A, Drubay, V, El amrani, M, Eveno, C, Lecolle, K, Legault, G, Martin, L, Piessen, G, Pruvot, FR, Truant, S, Zerbib, P, Ballouhey, Q, Barrat, B, Fourcade, L, Laloze, J, Salle, H, Taibi, A, Tricard, J, Usseglio, J, Bergeat, D, Merdrignac, A, Le Roy, B, Perotto, LO, Scalabre, A, Gornes, H, Vaysse, C, Vergriete, K, Aimé, A, Ezanno, A, Malgras, B, Arnaud, AP, Fustec, E, Lavoue, V, Tesson, C, Bouche, P, Tzedakis, S, Cotte, E, Glehen, O, Lifante, J, Bendjemar, L, Braham, H, Charre, L, El Arbi, N, Morel-chevillet, L, Police, A, Villefranque, V, Volpin, E, D'Urso, A, Felli, E, Mutter, D, Pessaux, P, Seeliger, B, Barbé, Y, Bardet, J, Barret, E, Berry, R, Boddaert, G, Bonnet, S, Brian, E, Cathala, N, Cathelineau, X, Denet, C, Fuks, D, Gossot, D, Grigoroiu, M, Laforest, A, Levy-Zauberman, Y, Louis-Sylvestre, C, Macek, P, Mombet, A, Moumen, A, Pourcher, G, Rozet, F, Sanchez Salas, R, Seguin-givelet, A, Tribillon, E, Crenn, V, De Vergie, S, Duchalais, E, Espitalier, F, Ferron, C, Fragnaud, H, Malard, O, Regenet, 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Brown, B, Collis, J, Duff, S, Khan, A, Moura, F, Taylor, M, Wadham, B, Warburton, H, Elmoslemany, T, Jenkinson, MD, Millward, CP, Zakaria, R, Mccluney, S, Parmar, C, Shah, S, Allison, J, Babar, MS, Bowen, J, Collard, B, Goodrum, S, Lau, K, Sargent, M, Scott, R, Thomas, E, Whitmore, H, Balasubramaniam, D, Jayasankar, B, Kapoor, S, Ramachandran, A, Semple, C, Elhamshary, A, Imam, SMB, Kapriniotis, K, Kasivisvanathan, V, Lindsay, J, Rakhshani-Moghadam, S, Beech, N, Chand, M, Green, L, Kalavrezos, N, Kiconco, H, McEwen, R, Schilling, C, Sinha, D, Pereca, J, Chopra, S, Egbeare, D, Thomas, R, Arumugam, S, Ibrahim, B, Khan, K, Combellack, T, Hill, G, Jones, S, Kornaszewska, M, Mohammed, M, Tahhan, G, Valtzoglou, V, Blencowe, N, Eskander, P, Gash, K, Gourbault, L, Hanna, M, Maccabe, TA, Main, B, Olivier, J, Newton, C, Roswadowski, S, Ryan, N, Teh, E, West, D, Al-omishy, H, Baig, M, Bates, H, Di Taranto, G, Dickson, K, Dunne, N, Gill, C, Howe, D, Jeevan, D, Khajuria, A, Martin-Ucar, A, McEvoy, K, Naredla, P, Robertson, S, Sait, M, Sarma, DR, Shanbhag, S, Shortland, T, Simmonds, S, Skillman, J, Tewari, N, Walton, G, Akhtar, MA, Brunt, A, McIntyre, J, Milne, K, Rashid, MM, Sgrò, A, Stewart, KE, Turnbull, A, Abou-Foul, AK, Gossedge, G, O'Donnell, S, Oldfield, F, Thomson, S, Aguilar Gonzalez, M, Talukder, S, Boyle, C, Fernando, D, Gallagher, K, Laird, A, Tham, D, Bath, M, Basnyat, P, Davis, H, Montauban, P, Shrestha, A, Agarwal, K, Arif, T, Magee, C, Nambirajan, T, Powell, S, Vinayagam, R, Flindall, I, Hanson, A, Mahendran, V, Green, S, Lim, M, MacDonald, L, Miu, V, Onos, L, Sheridan, K, Young, R, Alam, F, Griffiths, O, Houlden, C, Kolli, VS, Lala, AK, Leeson, S, Peevor, R, Seymour, Z, Consorti, E, Gonzalez, R, Grolman, R, Kwan-Feinberg, R, Liu, T, Merzlikin, O, Brown, A, Cooper, Z, Hirji, S, Jolissaint, J, Mahvi, D, Okafor, B, Raut, CP, Roxo, V, Salim, A, Bessen, S, Chen, L, Dagrosa, L, Fay, K, Fleischer, C, Hasson, R, Henderson, E, Leech, M, Loehrer, A, Markey, C, Paydarfar, J, Rosenkranz, K, Telma, K, Tocci, N, Wilkinson-Ryan, I, Bokenkamp, M, Brown, K, Fleming, D, Heron, C, Hill, C, Kay, H, Leede, E, McElhinney, K, Olson, KA, Osterberg, EC, Riley, C, Srikanth, P, Barbour, J, Blazer, D, DiLalla, GA, Fayanju, O, Hwang, ES, Kahmke, R, Kazaure, H, Lazarides, A, Lee, W, Lidsky, M, Menendez, C, Moris, D, Plichta, J, Pradhan, MC, Puscas, L, Rice, HE, Rocke, D, Rosenberger, L, Scheri, R, Smith, BD, Stang, MT, Tolnitch, L, Turnage, K, Visgauss, J, Walton, FS, Watts, T, Zani, S, Farma, J, Cardona, K, Russell, MC, Clark, J, Kwon, D, Goel, N, Kronenfeld, J, Bigelow, B, Etchill, E, Gabre-Kidan, A, Jenny, H, Kent, A, Ladd, MR, Long, C, Malapati, H, Margalit, A, Rapaport, S, Rose, J, Stevens, K, Tsai, L, Vervoort, D, Yesantharao, P, Dehal, A, Klaristenfeld, D, Huynh, K, Kaafarani, H, Naar, L, Qadan, M, Brown, L, Ganly, I, Mullinax, JE, Alpert, N, Gillezeau, C, Miles, DDS, Taioli, E, Cha, DE, Gleeson, E, Horn, C, Sarpel, U, Gusani, N, Hazelton, J, Maines, J, Oh, JS, Ssentongo, A, Ssentongo, P, Bhama, A, Colling, K, Najarian, M, Azam, M, Choudhry, A, Marx, W, Abedin, Y, Arzumanov, G, Chokshi, R, Gabrilovich, S, Glass, N, Kalyoussef, E, Parvin-Nejad, FP, Roden, D, Stein, J, Suarez-Ligon, A, Tsui, G, Zhao, K, Fleming, J, Fuson, A, Gigliotti, J, Ovaitt, A, Ying, Y, Abel, MK, Andaya, V, Bigay, K, Boeck, MA, Chern, H, Corvera, C, El-Sayed, I, Glencer, A, Ha, P, Hamilton, BCS, Heaton, C, Hirose, K, Jablons, DM, Kirkwood, KS, Kornblith, LZ, Kratz, JR, Lee, RH, Miller, PN, Nakakura, EK, Nunez-Garcia, B, O'Donnell, RJ, Ozgediz, D, Park, P, Robinson, B, Sarin, A, Sheu, B, Varma, MG, Wai, KC, Wustrack, R, Xu, MJ, Zimel, M, Beswick, D, Goddard, J, Manor, J, Song, J, Cioci, A, Pavlis, W, Rakoczy, K, Ruiz, G, Saberi, R, Fullmer, T, Gaskill, C, Gross, N, Kiong, K, Roland, CL, Zafar, SN, Abdallah, M, Abouassi, A, Aigbivbalu, E, Eid, J, George, B, Kulkarni, G, Marwan, H, Mehdi, M, San Andrés, M, Sundaresan, J, Aoun, SG, Ban, VS, Batjer, HH, Bosler, K, Caruso, J, Sumer, B, Abbott, D, Acher, A, Aiken, T, Barrett, J, Foley, E, Schwartz, PB, Hawkins, AT, Maiga, A, Ruzgar, NM, Sion, M, Ullrich, S, Laufer, J, Scasso, S, Al-Naggar, H, Al-Shehari, M, Almassaudi, A, Alsayadi, M, Alsayadi, R, Nahshal, M, Shream, S, AL-Ameri, S, and Aldawbali, M
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- 2021
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4. Modeling of neutron spectrum in the gamma spectroscopy measurements with Ge-detectors
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Knežević, D., Jovančević, N., Krmar, M., and Petrović, J.
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- 2016
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5. Studies of the Low-energy Gamma Background
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Bikit, K., Mrđa, D., Bikit, I., Slivka, J., Veskovic, M., and Knezevic, D.
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- 2014
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6. Effect of Nitrogen Fertilization on Winter Wheat Quality
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Zecevic, V., Knezevic, D., Boskovic, J., Micanovic, D., and Dozet, G.
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- 2010
7. GENETIC VARIABILITY OF WHEAT AS RELATED TO NITROGEN FIXATION BY ASSOCIATED RHIZOSPHERE MICROORGANISMS
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Micanovic, D., Knezevic, D., Saric, Z., and Saric, M.
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- 1997
8. Energy-Related Hormones in Raw and Retail Cow’s Milk and Possible Risk for Consumers
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Knežević Dragan, Bošnjaković Dušan, Dražić Slavica, Nedić Sreten, Vujanac Ivan, Valčić Olivera, Pantelić Marija, Stojiljković Mojca, Sladojević Željko, and Kirovski Danijela
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cows ,milk hormones ,consumer health ,Veterinary medicine ,SF600-1100 - Abstract
The study aimed to determine the concentration of energy-related hormones in cow’s milk and to consider them from a public health perspective. Fourteen Holstein cows were subjected to milk and blood sampling on the following days in lactation (DIL): 10, 30, 60, 90, 150, 180, 210, 250 and 280 to determine milk hormones, fat and protein content and blood biochemical parameters. For the same purpose, bulk-tank milk was sampled and samples of retail m ilk with 1.5% (CM1.5) and 3.2% (CM3.2) fat was purchased. Milk insulin-like growth factor-1 (IGF-1) values were significantly lower at 90, 150, 180, 210 and 250 and significantly higher at 10, 30 and 60 DIL than lactation average (LA). Milk insulin concentrations were significantly lower at 30, 60 and 90 and higher at 210, 250 and 280 DIL than LA. Free thyroxine (fT4) level in the milk was higher at 250 DIL, while milk free triiodothyronine (fT3) concentrations were lower at 30, 60, 90 and 280 DIL, and significantly higher at 10 and 180 DIL than respective LA. Milk cortisol levels were lower at 60 and 280 DIL than LA. All measured milk hormones were significantly lower in CM1.5 compared to CM3.2, bulk-tank milk and LA. An exception was the LA of IGF-1, which was significantly lower than the IGF-1 content in CM1.5. Blood biochemical parameters fluctuated evenly during lactation and were within the reference range. Hormone concentrations in cow’s milk fluctuate during lactation, giving milk an important role in the context of public health.
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- 2024
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9. Pure squamous cell carcinoma of primary pancreatic origin
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Mišković Bojana, Mitrović-Jovanović Milica, Tadić Boris, Šaponjski Dušan, and Knežević Đorđe
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squamous cell carcinoma ,computed tomography ,distal pancreatectomy ,Medicine - Abstract
Introduction. Primary, “pure” squamous cell carcinoma (SCC) is an exceptionally rare pancreatic malignancy that has been described in sporadic case reports. The appearance of this rare entity created a diagnostic dilemma for us, therefore, in this case report, we are focused on the radiological detection and characterization, pathogenesis, and therapeutic options of pure pancreatic SCC. Case outline. In an 80-year-old female patient, a partially necrotic mass in the tail of the pancreas was detected by computed tomography, which is the rarest localization of this tumor. On the performed imaging, the tumor showed predominantly malignant features with a surprising definitive histopathological diagnosis in the direction of pure SCC. Distal pancreatectomy with splenectomy was performed because of the infiltration of lienal vascular structures. Conclusion. Due to the very aggressive form of this tumor and poor prognosis, early detection, risk factors control, genetic burden, and optimization of surgical and therapeutic management can improve the quality of life and prolong the overall survival period.
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- 2024
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10. Analysis of the influence of the cost management approaches on the critical factors of project success
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Knežević Dunja Đ.
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costs ,cost management ,project success ,critical success factors ,Engineering (General). Civil engineering (General) ,TA1-2040 - Abstract
Cost management represents a fundamental element of successful project management in the modern business environment. With increasing demands for resource optimization within a limited budget, effective cost management becomes crucial for project success across various industries. This paper explores interaction between cost management and critical success factors of projects, focusing on identifying key aspects that directly or indirectly influence project success through efficient cost management. Through analysis of relevant literature and the application of appropriate research methodology, the aim of this paper is to provide a better understanding of how cost management approaches can impact various aspects of project success, as well as to identify effective practices that organizations can implement to enhance the performance of their projects.
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- 2024
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11. The relationship between gluten proteins and loaf volume
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Knežević Desimir, Kondić Danijela, Dragovich Aleksandra Yu., Kudryavtsev Alexander M., Matković-Stojšin Mirela, Zečević Veselinka, Radosavac Adriana, and Paunović Aleksandar
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wheat ,gliadin ,glutenin ,allele ,bread ,quality ,Agriculture (General) ,S1-972 - Abstract
The storage proteins influence technological quality value of grain wheat, dough quality traits, and loaf quality. The aim of this study is to estimate variability in the dry gluten content, loaf volume, and their relationships with encoding alleles of gliadin and glutenins. Wheat genotypes grown in two vegetation seasons (2015/16 and 2016/17) were studied. The technological quality traits analyzed in this study varied in wheat genotypes within and between vegetation seasons. In both vegetation seasons the highest dry gluten content was established in G-3621-1 (30.23% and 31.15%) and the highest value of loaf volume in G-3621-1 (530 ml and 540 ml). In both vegetation seasons the least dry gluten content was found in G-3606-6 (25.42% and 25.98%) and the least loaf volume in G-3606-6 (380 ml and 390 ml). The composition of gliadin and glutenin alleles in the wheat genotypes analyzed was different. The genotypes carrying Gli-B1b, Gli-D1b, Gli-D2b, and Glu-A1b, Glu-B1c, Glu-D1d had the highest gluten content, while the genotype that carried Gli-B1l and Glu-A1b, Glu-B1c, Glu-D1d had high bread volume. The results have shown relationships between gliadin and glutenin alleles and quality traits of grain, flour, and bread.
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- 2024
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12. Genetic analysis of nitrogen contents in four wheat cultivars and their hybrids
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Knezevic, D., Ando, Tadao, editor, Fujita, Kounosuke, editor, Mae, Tadahiko, editor, Matsumoto, Hideaki, editor, Mori, Satoshi, editor, and Sekiya, Jiro, editor
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- 1997
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13. Influence of native root microflora on wheat growth
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Micanovic, Danica, Zecevic, V., Knezevic, D., Raicevic, V., Ando, Tadao, editor, Fujita, Kounosuke, editor, Mae, Tadahiko, editor, Matsumoto, Hideaki, editor, Mori, Satoshi, editor, and Sekiya, Jiro, editor
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- 1997
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14. Development and implementation of a protocol for the prevention of Clostridioides difficile infections aimed at the improvement of nursing skills
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Knežević Darija, Jović Duška, Egeljić-Mihailović Nataša, and Dobrovoljski Daniela
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clostridioides difficile infections ,nurses ,sampling ,Nursing ,RT1-120 - Abstract
Introduction: Hospitalized patients have an increased risk of developing infections caused by Clostridioides difficile. Due to the changing epidemiology of C. difficile, it is necessary to educate nurses about the implementation of prevention measures, but also about the criteria for obtaining a quality sample of feces in order to establish an etiological diagnosis in a timely manner. The aim of the study was to assess gaps and flaws in C. difficile infection (CDI) prevention policies and practices, and to determine whether a nurses knowledge about early identification and isolation of CDI patients improved after education. Methods: The research was conducted in a quasi-experimental study at the University Clinical Center of the Republka Srpska (UKC RS) in the period from May 2020 to December 2021 on a sample of 60 nurses. A survey questionnaire Centers for Disease Control and Prevention (CDC) was used as a research instrument and it was intended for the assessment of knowledge, attitudes and understanding about procedures for the prevention of infection with C. difficile. The applied strategy to prevent hospital CDI was based on the introduction of the concept of "package of care", which was based on scientific evidence. For the education of nurses, interactive educational modules were used that contained detailed prevention measures CDI in hospital conditions in accordance with the guidelines. Before and after the education, the participants completed a knowledge test about C. difficile and prevention CDI.The study was approved by the Ethics Committee of the UKC RS. Results: Only 5 (8.3%) respondents stated that they were informed about CDI prevention during the visit of a nurse from the infection control team. Most of the shortcomings during the assessment of CDI prevention at the observed clinics were related to the practice of sending feces samples for laboratory testing for C. difficile. Nurses showed highly statistically significant (p
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- 2023
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15. The predictive role of biochemical markers on outcomes of severe COVID-19 patients admitted to intensive care unit
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Mirjanić-Azarić Bosa, Pejić Ivana, Mijić Smiljana, Pejčić Aleksandra, Đurđević-Svraka Anita, Svraka Dragan, Knežević Darija, Milivojac Tatjana, and Bogavac-Stanojević Nataša
- Subjects
covid-19 ,neutrophil-to-lymphocyte ratio ,systemic inflammation index ,d-dimer ,magnesium ,ferritin ,Biochemistry ,QD415-436 - Abstract
Background: The pandemic of severe acute respiratory syndrome by coronavirus 2 (SARS-CoV-2) is a multi-system disease caused by a diffuse systemic process involving a complex interaction of the inflammatory, immunological and coagulative cascades. This study aims to identify the most effective biomarkers to predict poor outcome in intensive care unit (ICU) patients with severe COVID-19 disease. Methods: A single-centre retrospective observational study enrolled 69 deceased and 20 recovered patients treated in the ICU of the General Hospital Gradiska in the period from March 1, 2021. until April 1, 2022. We evaluated the leukocytes (WBC), lymphocytes (LYM), neutrophils (NEU), platelets (PLT), haemoglobin, neutrophil-lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), and systemic immune-inflammation index (SII). In addition, we evaluated the IL-6, ferritin, CRP, D-dimer, magnesium, bilirubin and lactate dehydrogenase. Results: Between deceased and recovered patients on admission to the ICU, there was a significant difference between the following parameters: WBC x109/L 11.50 (8.86-14.75) vs. 9.40 (5.90-11.90), p =0.026; NEU x109/L 10.15 (7.81-12.74) vs. 8.60 (4.80-10.30) p=0.022; NLR 15.01 (10.60-24.33) vs. 9.45 (5.10-14.90) p=0.02; SII 3712 (2240-6543) vs. 1949 (993-3720) p=0.003. The magnesium level increased significantly over time in the patients who died, while the haemoglobin level and platelet count decreased. ROC analysis showed the following AUC values: WBC 0.774; NEU 0.781; NLR 0.786; SII 0.776; D-dimer 0.741, and bilirubin 0.713. Conclusion: In this retrospective study WBC, NEU, NLR, SII, D-dimer, and bilirubin determined at hospital admission had a high value in predicting death among patients with severe COVID-19.
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- 2023
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16. Characteristics of unintentional injuries in hospitalised children and adolescents - national retrospective study
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Jović Duška, Petrović-Tepić Snežana, Knežević Darija, Tepić Aleksandar, Burgić Sanela, Radmanović Vanja, and Burgić-Radmanović Marija
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unintentional injury ,child ,adolescent ,hospitalisation ,Medicine - Abstract
Introduction/Objective. Unintentional injuries is a global health issue among children and adolescents. The aim of this study was to examine the characteristics of unintentional injuries divided according to different age groups and sex among the children and adolescents who have been hospitalized in public hospitals of the Republic of Srpska, Bosnia and Herzegovina. Methods. A retrospective analysis of the e-base of the Agency for Certification, Accreditation and Health Care Quality Improvement of the Republic of Srpska data were collected from 10 public hospitals for patients aged ≤ 19 years, who have been hospitalized for unintentional injuries in the period of January 2018 and December 2020. Results. The study identified 1336 patients who were hospitalized for unintentional injuries, most of whom were boys (67.4%). Falls were the most frequent cause of hospitalization in children of all age categories (aged 1 (70.6%), 1–4 (59.1%), 5–9 (68.5%)) and adolescents aged 10–14 (64.1%), while road traffic injuries were the leading cause of hospitalization in adolescents aged 15–19 (62.6%). The cause of injury for the hospitalized patients were significantly related to age (p < 0.001) and sex (p < 0.05) groups. According to the nature of the injury in relation to the area of the body, the most frequent injuries were to the head (41.1%), caused by traffic accidents and falls. Conclusion. Since falls and road traffic injuries were the leading causes of hospitalization, preventive measures should be taken to reduce the frequency of these injuries.
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- 2023
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17. Epidemiological and clinical characteristics of patients with healthcare: Associated Clostridioides difficile infection before and during the COVID-19 pandemic
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Knežević Darija, Jović Duška, and Petković Miroslav
- Subjects
clostridioides difficile infections ,covid-19 pandemic ,risk factors ,disease outbreak ,Medicine - Abstract
Background/Aim: Diarrhoea that occurs as a result of the presence of Clostridium difficile (reclassified as Clostridioides difficile) is usually manifested as a hospital infection, usually after antibiotic treatment. The study aim was to assess the incidence, characteristics and outcomes of hospitalised patients with healthcare - associated Clostridioides difficile infection (HA - CDI) before and during the COVID-19 pandemic. Methods: This retrospective cohort study included patients older than 18, who met the HA - CDI case definition. The CDI diagnosis was made by demonstrating toxins A and B in stool samples using an immunochromatographic assay test and polymerase chain reaction (PCR). Results: The incidence of HA - CDI has significantly decreased from the preCOVID-19 period to the COVID-19 period (11.04 per 10,000 vs 6.49 per 10,000, p < 0.001). Before establishing the HA - CDI diagnosis, 41.4 % of patients used one antibiotic, 25.9 % used two and 11.2 % were treated with three or more antibiotics. Almost one half of the applied antibiotics were from the group that represents high risk for the development of HA - CDI. Multivariable logistic regression analysis showed that older age (OR = 3.4; 95 % CI = 0.9-12.4; p = 0.038) and complicated disease course (OR = 11.8; 95 % CI = 2.6-53.6; p ≤ 0.001) were associated with a higher risk of death. Conclusion: The incidence of HA - CDI has decreased during the observed period of the COVID-19 pandemic, however, no clear connection between the impact of the pandemic and incidence reduction was found. Due to unfavourable outcome of the treatment of HA - CDI patients during COVID-19 pandemic, the rational use of antibiotics is necessary.
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- 2023
18. The effect of tranexamic acid on the reduction of intraoperative and postoperative blood loss and thromboembolic risk in patients with hip fracture
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Stojadinovic Ivan B., Ristic Branko M., Knezevic Dragan R., Milenkovic Zoran S., Prodanovic Nikola S., Zornic Nenad R., and Milosevic Jelena B.
- Subjects
tranexamic acid ,hip fracture ,blood loss ,thromboembolism ,Medicine - Abstract
The aim of this study is to determine whether the use of tranexamic acid (TXA) in patients with hip fracture reduces intraoperative and postoperative blood loss, and on the other hand, whether it increases thromboembolic risk. The study was performed on patients with hip fracture for a period of one year. Patients were divided into two groups (1:1): the first group receiving TXA and the second group receiving placebo. The amount of blood aspiration during the surgery was measured as well as drainage in the postoperative period of 24 h. The occurrence of deep vein thrombosis (DVT) was monitored before and after the surgery by ultrasound of the lower extremities. The amount of total blood loss was two times lower in patients who received TXA (291.8 ± 65.5 mL of blood vs 634.7 ± 150.5 mL of blood). Among the patients who developed DVT, one patient was from the group that did not receive TXA, and two patients were from the group that received TXA. The use of TXA in patients with hip fracture significantly reduces intraoperative and postoperative blood loss, without a significant thromboembolic risk.
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- 2022
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19. Evaluation of unintentional falls among children and adolescents treated in emergency medical services
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Jović Duška, Petrović-Tepić Snežana, Knežević Darija, Dobrovoljski Daniela, Egeljić-Mihailović Nataša, Tepić Aleksandar, and Burgić-Radmanović Marija
- Subjects
unintentional fall ,children ,adolescents ,emergency medical services ,Nursing ,RT1-120 - Abstract
Introduction: Unintentional falls are the leading cause of traumatic injuries, without fatal consequences, with significant morbidity in the population of children and adolescents. Goal: The main goal of this research was to analyze the manner of falling in relation to age and gender, and to assess the type of injury and the anatomical region of the body affected by the injury sustained during a fall in patients ≤19 years of age treated in the emergency medical services in the Republic of Srpska. Material and methods: A cross-section study with retrospective analysis of the national e-database WebMedic from 11 emergency medical services between January 2018 and December 2020 was conducted. Research included patients with diagnosis of unintentional injury caused by a fall, aged ≤19 years. Descriptive statistics and the Chi-square test were used for comparisons between groups. Results: During the observed period, 857 cases of unintentional falls were identified, where 87.5% were referred for hospitalization. The group of children aged 0 to 9 years (55.7%) was more often treated for falls (p
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- 2022
20. Unintentional injuries of children and adolescents treated in emergency medical services: A cross-sectional study
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Jović Duška, Skela-Savič Brigita, Petrović-Tepić Snežana, Knežević Darija, Tepić Aleksandar, Burgić-Radmanović Marija, Dobrovoljski Daniela, and Egeljić-Mihailović Nataša
- Subjects
unintentional injury ,child ,adolescent ,emergency medical services ,Medicine - Abstract
Background/Aim: Unintentional injuries among children and adolescents have become a common issue in public healthcare. The study objective was to analyse the characteristics and identify predictors associated with unintentional injuries in children and adolescents treated in emergency medical services (EMS) in the Republic of Srpska, Bosnia and Herzegovina. Methods: A cross-section study with retrospective analysis of WebMedic e-database from 14 EMS, in the period between January 2018 and December 2020 was conducted. Research included patients with unintentional injuries, aged ≤ 19 years, of both sexes. For comparison between groups, Chi-squared and multivariate logistic regression were used in risk factor analysis. Results: A total of 1,856 cases were identified, most injuries resulted from falls (46.7 %) and traffic injuries (26.9 %). Boys were significantly more affected by injuries than girls (p < 0.001). Falls were the major cause for reporting to EMS among age groups of children (0-9 years) and adolescents (10-14 years), whereas injuries in traffic were dominant in adolescents aged 15 to 19. The most common injuries were head injuries (35.7 %). Risk factors of unintentional injuries were age (p < 0.001), sex (p = 0.046), weekday (p = 0.016), winter (p = 0.014), body region (head, abdomen, lower and upper limbs (p < 0.001), thorax (p = 0.009)). Conclusions: There were significant differences in characteristics of unintentional injuries according to age and sex. Chances for occurrence of unintentional injuries among children increased with their age, especially for boys. These differences might indicate areas where preventive measures should be undertaken.
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- 2022
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21. Development of selection criteria for improving grain yield in wheat grown in different agro-ecological environments
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Matković-Stojšin Mirela, Petrović Sofija, Banjac Borislav, Roljević-Nikolić Svetlana, Zečević Veselinka, Bačić Jasmina, Đorđević Radiša, and Knežević Desimir
- Subjects
variability ,correlations ,path analysis ,wheat ,solonetz ,chernozem ,Agriculture - Abstract
Various statistical methods were applied in this research: analysis of genetic parameters, Pearson's correlation, genotypic and phenotypic correlations, and Path analysis, with the aim of creating a selection criterion for increasing wheat grain yield. A two-year experimental study was conducted with twenty-seven wheat genotypes, grown on two localities: Rimski Šančevi (Bačka, Vojvodina), on Chernozem soil type; and Kumane (Banat, Vojvodina), on Solonjec soil type. The highest values of phenotypic coefficient of variation (CVp) had the grain weight per plant (17.44% on Chernozem and 13.81% on Solonetz), while the lowest value of CVp had the thousand grain weight (8.12% on Chernozem and 5.47% on Solonetz). On Chernozem, the value of the genotypic coefficient of variation (CVg) ranged from 1.51%, in the number of grains per spike, to 9.17% in the spike length, while on Solonetz, grain weight per plant had the lowest value of CVg (0.36%) and plant height the highest one (11.15%). At both localities, grain yield was in highly significant and positive correlations with all analyzed traits, except with plant height and spike length. In favorable environmental conditions (Chernozem), Path analysis revealed that grain yield directly depends on grain weight per spike (0.317**), number of grains per spike (0.232**) and spike weight (0.209**), and other analyzed traits have a positive indirect effect on grain yield over mentioned traits. Under salinity stress conditions, the grain weight per plant had the highest direct effect on grain yield (0.891**), which makes this trait a good selection criterion in breeding for salinity stress tolerance.
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- 2022
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22. Environmental cadmium and the risk of pancreatic cancer development
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Djordjevic, V., Knezevic, D., Kmezic, S., Wallace, D., and Buha, A.
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- 2018
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23. Corrigendum to “Endothelial dysfunction mediated by interleukin-18 in patients with ischemic heart disease undergoing coronary artery bypass grafting surgery” [Med. Hypotheses 104 (2017) 20–24]
- Author
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Sokolic, J., Sotosek Tokmadzic, V., Knezevic, D., Medved, I., Vukelic Damjani, N., Balen, S., Rakic, M., Lanca Bastiancic, A., and Laskarin, G.
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- 2018
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24. 18 - Production of biofuels via hydrothermal conversion
- Author
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Kersten, S.R.A., Knežević, D., and Venderbosch, R.H.
- Published
- 2011
- Full Text
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25. Faecal transplantation and Clostridioides difficile infection
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Knežević Darija A. and Petković Miroslav
- Subjects
faecal microbiota transplantation ,clostridioides difficile infection ,microbiota ,Medicine - Abstract
Faecal microbiota transplantation (FMT), known equally well as faecal transplantation or faecal bacteriotherapy, is the process of implanting the faecal suspension containing balanced microbiota from a healthy donor to the colon of a recipient patient. Excessive growth of Clostridioides difficile (C difficile) in the intestinal microbiota resulting from antibiotic consumption is currently a rising threat to public health. FMT is one of the most important, newer approaches to treating C difficile infections. Since C difficile is regarded as an opportunistic bacterium triggering disease in conditions of disturbed homeostasis of the intestinal microbiota, restoration of healthy intestinal microflora facilitates suppression of toxic strain of C difficile by anaerobic bacteria of normal intestinal microflora with concomitant cure. Nurses have important role in caring for patients after faecal transplantation.
- Published
- 2021
- Full Text
- View/download PDF
26. Prevention procedures for nurses during the COVID epidemic in acute care hospital: Experiences from Republika Srpska
- Author
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Knežević Darija, Trifunović Silvana, and Dobrovoljski Daniela
- Subjects
covid-19 disease ,nurses ,prevention measures ,procedures ,Nursing ,RT1-120 - Abstract
The epidemic of the COVID-19 disease presented a great threat to the public health. The SARS-CoV-2 virus is still spreading on a global level, so the accurate global number of the infected or deceased from the COVID-19 disease is yet to be estimated or correctly counted. The nurses have always played a great role in the prevention and control of infections, isolations and public health protection. The nurses' work during the COVID-19 epidemic has created a history of nursing. Nurses have been on the front line of defense from the SARSCov-2 virus for over a year now and many of them are already on the edge of endurance, both mentally and physically. The professional security is the key for the work of nurses who are facing the danger of infection on a daily basis. The aim of this paper is to show the actions and measures taken by the nurses in Republika Srpska that could help in the decrease of the global transmission of the infection. Compared with some European countries and their fight with the epidemic, Republika Srpska has maintained the number of confirmed cases on a level which can be controlled. The prevention measures are the only thing that can stop the spread of this new infectious disease. In our biggest healthcare institution of a tertiary level, a large number of COVID procedures for nurses and other healthcare workers have been released. Nurses are, together with other healthcare professionals, actively involved in the interventions around the COVID-19 and will be one of the key factors that will stop the pandemic.
- Published
- 2021
- Full Text
- View/download PDF
27. Modeling the relationship between the characteristics of agricultural holdings and the presence of organic farming
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Roljević-Nikolić Svetlana, Knežević Desimir, and Paraušić Vesna
- Subjects
holdings ,agricultural land ,livestock ,economic value ,organic production ,environment ,Agriculture - Abstract
Organic farming is a fast growing market segment in the global food industry. Ecological and health benefits of organic farming are frequently emphasized. In addition, we have recently witnessed the promotion of its role in the development of rural areas by means of creating jobs and strengthening ties with local economies. This paper analyzes the relationship between the presence of organic farming and the main characteristics of agricultural holdings in the case of European Union countries. The objective is to identify factors which have a significant relationship with the organic farming sector and which can affect its future development. The results have shown that large farms are dominant in farm land management in the EU, which is related to the fact that there is a significant correlation between the availability of agricultural areas and the economic value of farms (r = 0.881**). There is a positive and significant correlation between the economic value of a holding and the number of livestock units on the farm (r = 0.940**), which indicates that animal husbandry has strong economic potential. When it comes to the relationships between the structural and economic indicators of agricultural holdings and the presence of organic farming, the results have shown that the number of organic producers is positively and significantly correlated with the available agricultural areas (r = 0.675**), and a strongly positively correlated with the economic value of farms (r = 0.810**). The areas under organic farming are also directly correlated with the utilized agricultural area (r = 0.836**), as well as with the number of livestock units (r = 0.793**), but they are slightly negatively correlated with livestock density (r = -0.211). Therefore, high livestock density can be a limiting factor for the further intensive growth of organic farming areas, considering the significant impact of animal husbandry on the environment.
- Published
- 2021
- Full Text
- View/download PDF
28. Radon variability due to floor level in two typical residential buildings in Serbia
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Udovicic Vladimir, Veselinovic Nikola, Maletic Dimitrije, Banjanac Radomir, Dragic Aleksandar, Jokovic Dejan, Savic Mihailo, Knezevic David, and Savkovic Maja Eremic
- Subjects
radon variability ,time series ,Science - Abstract
It is well known that one of the factors that influence the indoor radon variability is the floor level of the buildings. Considering the fact that the main source of indoor radon is radon in soil gas, it is expected that the radon concentration decreases at higher floors. Thus at higher floors the dominant source of radon is originating from building materials, and in some cases there may be deviations from the generally established regularity. In such sense, we chose one freestanding single-family house with loft and other 16-floor high-rise residential building for this study. The indoor radon measurements were performed by two methods: passive and active. We used passive devices based on track-etched detectors: Radtrak2 Radonova. For the short-term indoor radon measurements, we used two active devices: SN1029 and SN1030 (manufactured by Sun Nuclear Corporation). The first device was fixed in the living room at the ground level and the second was moved through the floors of the residential building. Every measuring cycle at the specified floor lasted seven days with the sampling time of 2 h. The results show two different indoor radon behaviours regarding radon variability due to floor level. In the single-family house with loft we registered intense difference between radon concentration in the ground level and loft, while in the high-rise residential building the radon level was almost the same at all floors, and hence we may conclude that radon originated mainly from building materials.
- Published
- 2020
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- View/download PDF
29. Laparoscopic approach in the treatment of echinococcal liver disease - case report and literature review
- Author
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Grubor Nikola, Tadić Boris, Milosavljević Vladimir, Knežević Đorđe, and Matić Slavko
- Subjects
echinococcus granulosus ,liver cyst ,laparoscopy ,hydatid cyst ,laparoscopic fenestration ,Medicine - Abstract
Introduction. Cystic echinococcosis or hydatid disease is a parasitic disease, zoonosis, and is most commonly caused by Echinococcus granulosus larvae. It mainly occurs in endemic areas. The most common localization is the liver. Case outline. In this paper, we will present our experience with a 67-year-old female patient diagnosed with an echinococcal cyst in the right lobe of the liver, as confirmed by computed tomography examination of the abdomen. The patient underwent laparoscopic partial pericystectomy with omentoplasty. The operation went without complications, as well as the postoperative period. Conclusion. Laparoscopic partial pericystectomy is a safe and effective treatment of available hepatic hydatid cysts. Considering all the benefits of minimally invasive surgery, laparoscopic partial pericystectomy of hepatic hydatid cysts may be the treatment of choice, over the classical open surgery approach.
- Published
- 2020
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- View/download PDF
30. Large choledochal cyst initially interpreted as Mirizzi syndrome - case report and literature review
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Milosavljević Vladimir, Tadić Boris, Grubor Nikola, Knežević Đorđe, and Matić Slavko
- Subjects
choledochal cyst ,todani ,common hepatic duct ,icterus ,mirizzi syndrome ,Medicine - Abstract
Introduction. Choledochal cysts are congenital anomalies manifested as focal or diffuse cystic dilatation of the bile ducts. They are mostly diagnosed in childhood. The magnetic resonance and surgical management are the gold standard diagnostic and treatment modality. Case outline. We present a male patient who was presumed to have Mirizzi syndrome. This presumption was discarded by additional imaging procedures and by later surgical treatment. It was confirmed that it was a large choledochal cyst filled with stones. Considering the diagnosis and good patient’s general condition, we opted for surgical treatment. Conclusion. There are several surgical techniques that can be used in the treatment of choledochal cysts, wherein each is intended as a complete resection of the cyst with histological confirmation. Operative techniques do not affect the outcome of the treatment, but the time and extent of surgical resection, as well as any metaplasia of the epithelium, do.
- Published
- 2020
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- View/download PDF
31. Approaches in cereal breeding
- Author
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Knežević Desimir, Laze Artiona, Paunović Aleksandar, Đurović Vesna, Đukić Nevena, Valjarević Danijela, Kondić Danijela, Mićanović Danica, Živić Jelica, and Zečević Veselinka
- Subjects
breeding ,genotype ,biotechnology ,yield ,quality ,Agriculture - Abstract
The main goal of plant breeding is to improve quality traits, yield and resistance to abiotic and biotic stress factors. A thousand years ago, people selected the best plants, seeds or fruits to produce seed for new crops and food for human and animal nutrition. Modern plant breeding is based on genetic principles and contributes to increases in yield and quality components (contents of protein, amino acids, fat, sucrose, mineral elements etc.). Breeders in conventional breeding programs in the last six decades have made changes to plant phenotypes, significantly improved resistance to diseases, earliness, and frost and drought resistance, and improved scientific farming practices, baking and milling technologies, and beverage production technology. Through bioinformatics and improved technology, breeders have developed ways to improve and accelerate the breeding process to combine desired traits in new genotypes as well to operate at the level of individual cells and their chromosomes. Nowadays, modern biotechnology is used to improve human nutrition, and develop genotypes with significantly higher yields and quality compared with genotypes created by conventional breeding. By genetic modification it is possible to add, modify or delete a trait without interfering between two complete genomes. However, genetically modified crops can be used after their assessment in terms of human health, food safety and the environment.
- Published
- 2020
32. Combustion characteristics of several types of biofuel in a diesel engine
- Author
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Knežević Dragan M., Petrović Velimir S., Vorotović Goran S., Pajković Vladimir R., and Bralović Predrag D.
- Subjects
diesel engine ,combustion process ,biofuels ,heat release rate ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Mechanics of engineering. Applied mechanics ,TA349-359 - Abstract
Alternative propulsion fuels for diesel engines were highlights for a variety of research activities within a large number of R&D labs in the world. Curiosity, as well as basic interest in alternative fuel has been immense because of its reproducibility, renewability, as well as good ecological characteristics. Another reason for this interest is a favorable impact on the economies of the countries engaged in their production, by processing that kind of bio fuel. This paper presents the results of testing and research of the three types of alternative fuel gained from bio oil. Analyses and comparison of the dynamics of combustion process of these alternative fuels were done in relation to the reference diesel fuel. Burning process of methyl esters rapeseed (RME100), soya oil (SME100), waste cooking palm oil (PME100), as well as of regular Euro diesel fuel were investigated. It was found that these fuels were highly usable in diesel engines if they had been produced according to a proper standard procedure under standard EN 14214. The application of bio fuel is also very interesting for the propulsion of agricultural engines and machinery, because it enables the individual farming of bio fuel products necessary for the appropriate own machinery.
- Published
- 2020
33. Nuclear structure data obtained by the (nth,2γ) reaction
- Author
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Jovancevic Nikola, Knezevic David, Stieghorst Christian, Revay Zsolt, and Krmar Miodrag
- Subjects
Physics ,QC1-999 - Abstract
The determination of nuclear structure parameters such as gamma transitions, level scheme, nuclear level density and radiative strength functions is one of the most important tasks in low-energy nuclear physics. The two-step gamma cascades method based on detection of gamma coincidences following neutron capture, ie. the (n,2γ) reaction has been proven to give spectroscopic data and data concerning level density and radiative strength function. This method allows for the study of the dynamics of interaction and inter-transition between Fermi-and Bose-states of the nucleus near the neutron binding energy. There is an essential difference between these intranuclear processes from those in classical and high-temperature superfluidity, which is determined by a shape of the investigated nucleus, the nucleon parity in it, existence of nucleons of different types (protons and neutrons) etc. Two-step gamma cascades technique has so far been successfully applied for 45 nuclei in the mass region 28
- Published
- 2023
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- View/download PDF
34. Role of hepatic stellate cells (HSCs) in the development of hepatic fibrosis in cats with polycystic kidney disease (PKD)
- Author
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Aleksić-Kovačević, Sanja, Kukolj, Vladimir, Kureljušić, Branislav, Marinković, Darko, Knežević, Đ., Ignjatović, I., Jovanović, M., Knežević, Milijana, Gledić, Dušan, Aleksić-Kovačević, Sanja, Kukolj, Vladimir, Kureljušić, Branislav, Marinković, Darko, Knežević, Đ., Ignjatović, I., Jovanović, M., Knežević, Milijana, and Gledić, Dušan
- Abstract
Hepatic stellate cells (HSCs) play a significant role in hepatic fibrogenesis. In the following study we described the distribution of cells that express alpha-smooth muscle actin (α-SMA) and desmin in the cat liver with various degrees of fibrosis, as well as the significance of hepatic stellate cells and portal myofibroblasts in the genesis of fibrosis in cats with polycistic kidney disease. Liver samples from 15 necropsied Persian cats were examined microscopically, using H&E and Masson-trichrom methods and immunohistology for α-SMA and desmin. Liver fibrosis was confirmed in cats with terminal stage of chronic cholangiohepatitis and it was characterized by connective tissue septa which divide the liver parenchyma into irregular lobuli. Inflammation in the cat liver is connected with the activation of periductal myofibroblasts. The intensity of immunopositivity of perisinusoidal HSCs to α-SMA and desmin varied depending on the degree of fibrosis and was the strongest in livers of cats with cirrhosis., U ovom radu je opisana distribucija ćelija koje eksprimiraju α-glatkomišićni aktin (α-SMA) i dezmin u jetri mačaka sa različitim stadijumom fibroze, kao i značaj ovih ćelija u razvoju fibroze, kod mačaka sa policističnim bubrezima. Mikroskopski su ispitani uzorci jetre od 15 obdukovanih persijskih mačaka, korišćenjem HE i Mason-trihromnog bojenja i imunohistohemijski na α-SMA i dezmin. Fibroza jetre potvrđena je kod mačaka sa terminalnim stadijumom hroničnog holangiohepatitisa i odlikovala se prisustvom vezivno-tkivnih septi koje dele parenhim na nejednake lobuluse. Inflamacija u jetri mačaka u vezi je sa aktivacijom periduktalnih miofibroblasta. Intenzitet imunohistohemijske reakcije perisinusoidnih HSCs na α-SMA i dezmin razlikovala se od stepena fibroze i bio je najjači u jetri mačaka sa cirozom.
- Published
- 2010
35. Expression of α-SMA, desmin and vimentin in canine liver with fibrosis
- Author
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Knežević, Milijana, Gledić, Dušan, Kukolj, Vladimir, Knežević, Đ., Jovanović, Milan, Božić, Tatjana, Aleksić-Kovačević, Sanja, Knežević, Milijana, Gledić, Dušan, Kukolj, Vladimir, Knežević, Đ., Jovanović, Milan, Božić, Tatjana, and Aleksić-Kovačević, Sanja
- Abstract
In this work, 36 canine livers with fibrosis were examined. Based on the degree of fibrosis, the livers were classified into three groups: 1- mild portal fibrosis; 2- moderate portal fibrosis with mild periportal and septal fibrosis; 3- severe portal fibrosis with marked periportal and septal fibrosis or cirrhosis. Normal liver sections obtained from five dogs with no evidence of infectious, neoplastic, or cardiovascular diseases were used as controls. The degree of fibrosis was evaluated on liver sections stained according to Masson's trichrome method. It was proved using an immunohistochemical method that HSC and periductal myofibroblasts are immunoreactive to desmin, vimentin and α-SMA. Desmin, vimentin and α-SMA positive cells in the portal triad were significantly more numerous in dogs with fibrosis of the third degree than in the controls or all other examined livers. The density of α- SMA, vimentin and desmin-positive cells in the portal triad was in correlation with the degree of fibrosis, which cannot be said for HSC. These results suggest that portal myofibroblasts have a significant role in the process of liver fibrosis in dogs., U ovom radu su prikazani rezultati ispitivanja 36 uzoraka tkiva jetre sa znacima fibroze, poreklom od pasa. Na osnovu stepena fibroze, uzorci su klasifikovani u tri grupe: 1 - blaga portalna fibroza; 2 - umerena portalna fibroza sa blagom periportalnom i septalnom fibrozom; 3 - teška portalna fibroza sa izraženom periportalnom i septalnom fibrozom ili cirozom. Kao kontrola su korišćeni uzorci tkiva jetre dobijeni od pet pasa bez znakova infekcije, neoplazije i kardiovaskularnih bolesti. Evaluacija stepena fibroze je urađena na isečcima jetre bojenim po Masson trihromnoj metodi. Imunohistohemijskom metodom je pokazano da su HSC i periduktalni miofibroblasti imunoreaktivni na dezmin, vimentin i α-SMA. Dezmin, vimentin i α-SMA, pozitivne ćelije u portalnoj trijadi bile su značajno brojnije kod pasa sa fibrozom trećeg stepena u odnosu na kontrolu i na sve druge ispitivane uzorke tkiva jetre. Gustina α-SMA, vimentin i dezmin pozitivnih ćelija u portalnoj trijadi je bila u korelaciji sa stepenom fibroze, što se ne može reći i za HSC. Ovi rezultati sugerišu da portalni miofibroblasti imaju značajnu ulogu u procesu fibroze jetre kod pasa.
- Published
- 2009
36. Laparoscopic splenectomy in the treatment of splenic artery aneurysm - case report and literature review
- Author
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Milosavljević Vladimir, Tadić Boris, Grubor Nikola, Knežević Đorđe, and Matić Slavko
- Subjects
spleen ,aneurysm ,splenic artery ,laparoscopic splenectomy ,Medicine - Abstract
Introduction. Splenic artery aneurysm is the most common visceral aneurysm with a prevalence of 0.2–10%. It is the third most frequent abdominal aneurysm as well. It can be true or false. It occurs more often in women than in men. We present our experience with a 34-year-old female patient who underwent laparoscopic splenectomy due to the splenic aneurysm located in the splenic hilum. Case outline. We present a case of a 34-year-old female patient diagnosed with an enlarged splenic artery during a routine abdominal ultrasound examination. Abdominal scan and computed tomography angiography showed saccular aneurysm of the splenic artery located in the hilum of the spleen, 24 × 17 mm in size. Given the good general condition and age of the patient, we decided to perform laparoscopic splenectomy. The operation was performed without complications, which was also the case with the postoperative flow. The patient was discharged from the hospital on the third postoperative day. Conclusion. Laparoscopic splenectomy is a safe and effective modality for the treatment of splenic artery aneurysm, localized in the splenic hilum. Considering all the benefits of minimally invasive surgery, laparoscopic splenectomy should be the treatment of choice, over the classical open approach.
- Published
- 2019
- Full Text
- View/download PDF
37. Mine waste
- Author
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Nišić Dragana D., Cvjetić Aleksandar S., and Knežević Dinko N.
- Subjects
mining ,flotation tailings ,sustainable development ,waste management ,disposal ,Engineering (General). Civil engineering (General) ,TA1-2040 - Abstract
Mine waste has aroused the attention of the expert and lay public with its quantity and characteristics for many years. The expert public approaches it from the point of view of the possibility of rational treatment, and the lay public with fear for the environment and sustainable development. One would solve the problem gradually according to available resources, and others would give up mining, at any cost and by a short procedure. This creates the impression that mining is marked with its waste, not with a multitude of useful products without which the current and future development is unimaginable. Starting from these premises, in this paper mine waste is shown through legislation, its general characteristics, risk and management strategies, with the problems that accompany it. The essential problem is reduced to quantities that inevitably stand out in mining processes and the need to solve the problem of disposal of such waste in accordance with its characteristics.
- Published
- 2019
38. Variability in seed germination of barley cultivars (Hordeum vulgare L.) grown under different nitrogen application rates
- Author
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Knežević Desimir, Paunović Aleksandar, Kondić Danijela, Radosavac Adriana, Laze Artiona, Kovačević Vlado, and Mićanović Danica
- Subjects
barley ,variability ,seed germination ,nitrogen rate ,Agriculture - Abstract
Variability in the percentage of seed germination was studied in four winter barley cultivars ('Jagodinac', 'Premium', 'NS 489' and 'NS 495'), grown under four nitrogen application rates (control N0=0, N1=20, N2=40 and N3=60 kg ha-1) during two years of the experiment. The experiment was carried out as a randomised block design in 5m2 plots and with four replications. In both experimental years, the average seed germination was over 90.0% for all barley cultivars and in each nitrogen fertilisation treatment. The maximum seed germination percentage was 98.0% in 'Premium' in the second year in the treatment N3=60 kg ha-1, and minimum germination percentage (90.1%) was also recorded in 'Premium' 'in the first year of the experiment in the unfertilised control (N0=0 kg ha-1). The obtained values of seed germination significantly differed among cultivars in the first and second year. Also, the average values of seed germination under four N fertilisation treatments were significantly different in both years. The average values for both years of the experiment were significantly different among cultivars and treatments. The values of seed germination for all cultivars increased with increasing nitrogen rates, suggesting that phenotypic variability in seed germination was affected by nitrogen fertilisation, which indicated a high value (81.87%) of the component of phenotypic variance for seed germination.
- Published
- 2019
39. Preferences of customers and improvement of production and sales of organic products in Serbia
- Author
-
Dašić Goran, Radosavac Adriana, Knežević Desimir, and Đervida Ružica
- Subjects
organic farming ,internet ,marketing ,incentives to agriculture ,Agriculture - Abstract
Promotion and sale of organic products require particular approach to introduce customers about the branding, packaging and advantages in comparison to conventional products. The aim of work is investigation which are sources of promotion of organic products use customers and effects of sources on trade improvement. In this study conducted interviews of 400 of customers through the mail. The results showed differences among customers according to: sources of their information about traits of products and market place, and their behavior and decision for use of organic product. Women more often use electronic media, professional literature, while man use magazine as a source of information. Both gender, male and female used internet equally. Customers old between 21 and 40 years more often bought in supermarkets and specialized stores, while customers of age between 41 and 60 years more often bought directly on market from producers. Customers who have more than 60 years buy on the market from producers and the supermarket. This differences depends of gender, age, education, as well as place of residence of customers.
- Published
- 2019
40. Effect of cereals + pea intercropping on spike index of spring wheat, triticale, oat and pods index of pea
- Author
-
Grčak Milosav, Grčak Dragan, Župunski Vesna, Jevtić Radivoje, Lalošević Mirjana, Radosavac Adriana, Kondić Danijela, Živić Jelica, Paunović Aleksandar, Zećević Veselinka, Mićanović Danica, and Knežević Desimir
- Subjects
spike index ,pod index ,intercrops ,cereals ,pea ,Agriculture - Abstract
Advantages or disadvantages of intercropping system can estimate through expression of components of yield on the base of values of productive organs (spike, pod). The aim of this work was study of variation of spike index in cereals species and pods index in pea of spring intercropping. For investigation included spring species of small grains: wheat, triticale, oat and spring legume pea. The investigation was carried out in field condition in experiment with randomised block design of 5m2 plots, with 4 replications. Each species (cereals and pea) were sown sole and in intercrops wheat+pea, triticale+pea and oat+pea. At the maturity stage used 40 plants (10 plants/replication) for determining harvest index of spike in cereal species and index of pea pods on the base of analysis of spike mass and pod mass and seed mass spike-1 and seed mass pod-1 . Seed mass spike-1 of small grains species genotypes variate in ratio of 0.85 g (wheat+pea) and 1.59 g (oat intercrops) with average 1.19 g for all crops of cereals and variant of cultivation. The spike mass variate in range of 1.37 g (triticale intercrop) and 2.23 g (wheat intercrops) with average 1.72 g for all cereals and variant of cultivation. Harvest index of spike variate between 62.5% (triticale sole) and 89.2% (oat sole). The value of spike mass was the higher in wheat intercrops than in wheat sole, while for triticale and oat spike mass is lower in intercrops. In the same of analyzed small grain species, seed mass was the higher in sole crops than in mixture with pea. The spike index, only in intercrop triticale+pea (63.2%) was slightly higher than in single crop of triticale (62.5%). Pod mass and seed mass pod-1 of pea was the higher in pea intercrops than in pea sole. The highest pod mass was in intercrop pea+triticale (0.72 g) and the least in single crop of pea (0.45 g) with average 0.62 g for all crops. The highest seed mass pod-1 was the highest intercrop pea+triticale (0.56g) and the least in monocrop of pea (0.32 g) with average 0.46 g for all crops. Harvest index of pod variate in ratio 68.0% (pea single) and 77.% in pea/triticale intercrop. Pod index of pea in mixture with each small grains species genotypes was higher than in pea's monocrop. On the base of result we can conclude that intercropping cereals + pea, have positive effect on spike and pod characteristics which values were higher in majority of studied intercrops than in monocrops.
- Published
- 2019
41. Estimation of the sky radiance
- Author
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Knežević Dragan, Nikolić Zoran, Mišković Katarina, and Vasiljević Darko
- Subjects
infrared ,sky ,radiation ,radiance ,temperature ,thermal imaging camera ,uniformity ,contrast ,signature ,atmosphere ,skewness ,kurtosis ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 - Abstract
For the infrared prefilter model there was a need for testing the sky radiation and defining its fluctuations within the zone of neighborhood area for the current frame and tests of repeatability. It was necessary to do the statistical processing of sky fluctuations in the current frame, because the sky is represented by corresponding layers through which the infrared image prefiltration is done. In this paper the uniformity for low elevation angles has been confirmed. The lower effective temperatures differences exist at large elevation angles.
- Published
- 2019
42. Assessment of the correlation between grain yield and its components in spring barley on an acidic soil
- Author
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Madić Milomirka, Knežević Desimir, Đurović Dragan, Paunović Aleksandar, Stevović Vladeta, Tomić Dalibor, and Đekić Vera
- Subjects
barley ,liming ,mineral fertilisers ,correlation ,yield ,Agriculture - Abstract
A field trial was conducted in 2016-2017 to determine the effect of different rates of mineral fertilisers, especially phosphorus, and lime on grain yield, yield components and their correlation in the spring barley cultivars 'Dunavac' and 'Novosadski 456' under dryland farming conditions at the experimental field of the Secondary School of Agriculture, Kraljevo. The experiment was performed on a very acidic soil (pHH2O 4.5), in a randomised block design with three replications. Grain yield, stem length, number of spikes m-2, spike length, number of grains per spike and grain weight per spike increased in response to mineral fertilisers and lime. Both cultivars performed better under mineral fertilisation and liming treatment than under increased phosphorus fertilisation, as the availability of macro- and micronutrients increased with increasing soil pH i.e. due to phosphorus immobilisation in the highly acidic environment. In general, significant positive correlations were observed among yield components, and between grain yield and its components. Grain yield was significantly positively correlated with number of spikes m-2, spike length, number of grains per spike and stem length. Correlations between grain yield and its components under diverse agroenvironmental conditions can guide the selection of cultural practices as well as the choice of cultivars for unfavourable growing conditions.
- Published
- 2019
43. LBA22 - A Prospectively-Designed Study to Determine the Association of a 17-Gene Genomic Prostate Score with Recurrence Following Surgery for Localised Prostate Cancer (Pca)
- Author
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Cullen, J., Rosner, I., Brand, T., Ali, A., Chen, Y., Zhang, N., Tsiatis, A., Knezevic, D., Maddala, T., Lawrence, H.J., Febbo, P., Srivastava, S., Sesterhenn, I., and McLeod, D.
- Published
- 2014
- Full Text
- View/download PDF
44. 814PD - Genomic Renal Score for Assessing Risk of Recurrence in Renal Cancer: Subgroup Analyses from the Validation Study
- Author
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Escudier, B., Koscielny, S., Lopatin, M., Svedman, C., Verkarre, V., Radulescu, C., Neuzillet, Y., Timsit, M., Hemmerlé, I., Tsiatis, T., Bonham, M., Knezevic, D., Lebret, T., Goddard, A., and Mejean, A.
- Published
- 2014
- Full Text
- View/download PDF
45. Morphological Characteristics of Two-rowed Barley (Hordeum sativum ssp. distichum L.) Landraces Originating from Herzegovina
- Author
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Kovačević Ivan, Hajder Đurađ, Kondić Danijela, Mandić Dragan, and Knežević Desimir
- Subjects
barley ,local population ,characterization ,evaluation ,productivity ,Agriculture (General) ,S1-972 - Abstract
Barley is a small grain cereal, tolerant to high temperatures and drought. Due to this characteristic, it can be regarded as a promising crop for production in dry conditions. Research on five spring landraces of two-rowed barley lasted two experimental years (2011 and 2012) in agro-ecological conditions of Banja Luka. In the experiment, the standard cropping practices were applied, without irrigation. The experiment was set as a complete randomized design with four replications. All measurements were performed in 10 plants per replication. Morphological characteristics included plant height (cm), spike length (cm), grain number per spike and grain weight per spike (g). Obtained data were subjected to two-way analysis of variance with landrace and growing season as main factors. Significant treatment or interaction effects were further analysed by Fisher's least significant difference (LSD) test, often utilized for pairwise comparisons among arithmetic means. In all tested traits the maximum average values were obtained in barley landrace AM2, i.e. the plant height (86.89 cm), the spike length (8.90 cm), the grain number per spike (24.74) and the grain weight per spike (1.17 g). Due to these facts, two-rowed barley landrace AM2 can be marked as the most productive in this research, bearing a potential for different crop breeding practices.
- Published
- 2018
- Full Text
- View/download PDF
46. A closure of the first phase of the flotation tailings storage facility 'Pekina glavica'
- Author
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Nišić Dragana D., Knežević Dinko N., Ilinčić Luka M., and Gogić Goran M.
- Subjects
Šuplja stijena mine ,closure of the flotation tailings storage facility ,multilayers covering system ,acid mine drainage ,Engineering (General). Civil engineering (General) ,TA1-2040 - Abstract
First phase closure of the flotation tailings storage facility 'Pekina Glavica' at the mine 'Suplja stijena', Sula - Montenegro has been shown in this paper. The mine has opted for the multiphase development of the flotation tailings storage facility, so by activating the third phase, the conditions for first phase tailings storage facility closure has been met. Dry closure method has been selected by applying multilayers of materials with different characteristics, which is in accordance with the recommendations of the International Commission on Large Dams (ICOLD). Earth materials extracted from the floor of the third tailings storage facility, overburden from the open pit mine and coarse tailings from the preconcentration process were mainly used. Five layers of a total thickness of 1,6 m were planned, but total thickness exceeded 4 m, because of the excess soil material from the floor. This closure method met the requirements of urban planners and environmentalists, and local residents were satisfied with closure and biotechnical rehabilitation. The closure has become financially sustainable for the company because of the rational use of available resources.
- Published
- 2018
47. State of agro-food foreign trade in Bosnia and Herzegovina
- Author
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Milovanović Mirjana, Radosavac Adriana, and Knežević Desimir
- Subjects
agricultural products ,production ,food ,market ,trade ,economy ,Agriculture - Abstract
Trade of agricultural products plays an important role in food security, development of production and processing of products, strengthening the economy and GDP growth. The aim of this paper is to establish the trend of trade of food, live animals, drinks and tobacco in Bosnia and Herzegovina (B&H). Foreign trade of food products in B&H has been investigated for the past six years (2012- 2017). In B&H, annual import of agricultural and food products exceeds BAM 2.5 million and the export is approximately BAM 600 million. Food production is a strategic interest of every country. The coverage of import by export was the highest in 2017 (29.9%) and 2016 (29.4%), while the lowest was in 2014 (18.4%). During the investigated period, there was a deficit of trade in B&H. Both export and import in agro-food sector have been increasing recently, while the volume of export has a higher growth than import.
- Published
- 2018
48. Content of TDF, SDF and IDF in Cereals Grown by Organic and Conventional Farming – a Short Report
- Author
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Menkovska Mirjana, Levkov Vesna, Damjanovski Dragan, Gjorgovska Natasha, Knezevic Desimir, Nikolova Nedeljka, and Andreevska Danica
- Subjects
dietary fibre fractions ,wheat ,barley ,rye ,oat ,millet ,Nutrition. Foods and food supply ,TX341-641 - Abstract
The objectives of this article were to determine the content of total dietary fibre (TDF) as well as of its fractions – soluble dietary fibre (SDF) and insoluble dietary fibre (IDF) of different cereals grown by conventional and organic farming in Macedonia, as well as to find out the influence of the cereal type and farming method on their values. Standardized enzymatic-gravimetric method (Megazyme Total Dietary Fiber Kit) was used for determination of soluble, insoluble, and total dietary fiber in 27 different cereal samples of wheat, rye, barley, oat, and millet, which were grown at three locations. The content of TDF, IDF and SDF was influenced by both cereal type and farming type. The organically grown cereals, primarily oat and barley, have shown higher values of TDF and of its fractions than the conventionally grown cereals. Their values (% db) for oat and barley for TDF were 42.00±1.39 and 21.91±2.01, for IDF 39.22±0.58 and 15.06±1.84 and for SDF 2.78±1.25 and 6.85±3.85, respectively. Barley grown by either organic or in conversion farming method proved to have the highest value of SDF content among the other cereals investigated, whereas oat produced by organic farming method exhibited the highest values of TDF and ISF content. The organic farming method proved to have a good perspective in cereal processing and technology, food market and nutrition.
- Published
- 2017
- Full Text
- View/download PDF
49. Variability of number of spikes per unit area and grain yield effected by different sowing densities of winter wheat (triticum aestivum L.)
- Author
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Kondić Danijela, Bajić Maja, Hajder Đurađ, and Knežević Desimir
- Subjects
genotype ,sowing rate ,yield ,number of spikes m -2 ,environment ,Agriculture (General) ,S1-972 - Abstract
The sowing density of wheat is important for expression of number of spikes per unit area, grain yield as well as other yield components. The aim of this work is investigation of variability of grain yield and number of spikes per unit area influenced by different sowing densities under different environmental conditions. Three wheat genotypes NS 40, Prima and Nova Bosanka were studied at seven different sowing densities (384, 424, 451, 504, 544, 588 and 604 seeds m-2) with four replications on experimental plot of one m 2 on field experiment in agro-ecological conditions of Banja Luka during two successive growing seasons. In all studied wheat cultivars, the lowest number of spikes m-2 and the lowest grain yield were found on variant of lowest sowing density (384 seeds m-2), while the highest number of spikes m-2 and the highest grain yield were found on variant of 588 seeds m-2 in both years. The wheat genotype NS 40S had the highest number of spikes m-2 , while Nova Bosanka had the lowest at all variants of sowing densities in both years. Mainly, at all variants of sowing densities, the highest values of analyzed traits were expressed in first year of experimental investigation. Depending of year and variant of sowing density the highest grain yield were found in NS 40 and Prima, while the lowest grain yield had Nova Bosanka in both years of experiment. In general, the recommended wheat sowing rates should be confirmed in the specific area of production and for the specific genotype.
- Published
- 2017
- Full Text
- View/download PDF
50. The spike characteristics of winter wheat (Triticum aestivum L.) varieties in agro-ecological conditions of Banja Luka region
- Author
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Kondić Danijela, Bajić Maja, Hajder Đurađ, Knežević Desimir, and Bosančić Borut
- Subjects
cultivar ,sowing density ,productivity ,grain ,interaction ,Agriculture (General) ,S1-972 - Abstract
The aim of this study was to analyze the spike length, number of grains per spike and grain weight per spike of winter wheat in agro-ecological conditions of Banja Luka at different sowing densities. Three winter wheat varieties (NS 40S, Prima and Nova Bosanka) were examined at seven sowing densities (384, 424, 451, 504, 544, 588 and 604 seeds/m2 ) in two growing seasons (2013/14 and 2014/15). Experimental design was a completely random system with four replications. In all wheat varieties, sowing was carried out from the 6th to 8th November in 2013/14 and from the 3rd to 5th November in 2014/15. Sampling of plants was done in the first decade of July in both experimental years. Factorial ANOVA 2×8×3 and LSD-test were performed, with year, sowing density and variety as main factors. For different varieties, the average number of grains per spike ranged from 34.53 to 38.19 while the average grain weight per spike (g) ranged from 1.58 to 1.73 g. The spike length ranged from 7.58 to 8.20 cm for varieties with statistically significant interaction effect variety × year at P ≤ 0.01. Spike parameters were generally higher in the second experimental year (2014/15).
- Published
- 2017
- Full Text
- View/download PDF
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