35 results on '"Kmieć K"'
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2. A flexible and effcient microscopic simulation of multiple GEM chamber based on Garfield++
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Bellini, V, primary, Brio, V, additional, Cisbani, E, additional, Kmieć, K, additional, Lagamba, L, additional, Perrino, R, additional, Petta, C, additional, Re, L, additional, and Sutera, C, additional
- Published
- 2020
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3. Magnetic susceptibility and 119Sn Mössbauer spectroscopy studies of RAuSn compounds (R=La, Ce, Pr)
- Author
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Łątka, K., Chajec, W., Kmieć, K., and Pacyna, A.W.J.
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- 2001
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4. The effect of galling aphids feeding on photosynthesis photochemistry of elm trees (Ulmus sp.)
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Kmieć, K., primary, Rubinowska, K., additional, Michałek, W., additional, and Sytykiewicz, H., additional
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- 2018
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5. The effect of Tetraneura ulmi L. galling process on the activity of amino acid decarboxylases and the content of biogenic amines in Siberian elm tissues
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Kmieć, K., primary, Sempruch, C., additional, Chrzanowski, G., additional, and Czerniewicz, P., additional
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- 2017
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6. Physiological Response of Orchids to Mealybugs (Hemiptera: Pseudococcidae) Infestation
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Kmieć, K., primary, Kot, I., additional, Golan, K., additional, Górska-Drabik, E., additional, Łagowska, B., additional, Rubinowska, K., additional, and Michałek, W., additional
- Published
- 2016
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7. The effect of Tetraneura ulmi L. galling process on the activity of amino acid decarboxylases and the content of biogenic amines in Siberian elm tissues.
- Author
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Kmieć, K., Sempruch, C., Chrzanowski, G., and Czerniewicz, P.
- Subjects
- *
ANGIOSPERMS , *PUTRESCINE , *SPERMIDINE , *TRYPTAMINE , *HISTAMINE - Abstract
Tetraneura ulmi (L.), a member of Eriosomatinae subfamily, is one of the gall-forming aphids occurring on elms. Sap-sucking behaviour of founding mothers results in the formation of new plant organs. This study documents the changes in the content of plant biogenic amines (putrescine, cadaverine, spermidine, tryptamine, spermine and histamine) and key enzymes of their biosynthesis: lysine decarboxylase (LDC), tyrosine decarboxylase and ornithine decarboxylase (ODC) in galls and other parts of Siberian elm (Ulmus pumila L.) leaves during the galling process. The direction and intensity of these changes for particular amines and enzymes were dependent on the stage of gall development and part of the galling leaf. Generally, the amine content tended to increase in gall tissues during the 1st and 2nd period of the galling process and decreased in later phases. LDC and ODC activities were markedly enhanced, especially in gall tissues at the initial stage of the galling process. [ABSTRACT FROM AUTHOR]
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- 2018
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8. The effect of mealybug Pseudococcus longispinus (Targioni Tozzetti) infestation of different density on physiological responses of Phalaenopsis × hybridum ‘Innocence’
- Author
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Kot, I., primary, Kmieć, K., additional, Górska-Drabik, E., additional, Golan, K., additional, Rubinowska, K., additional, and Łagowska, B., additional
- Published
- 2015
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9. Study on intensity of infestation, biology and harmfulness of wolly beech aphid (Phyllaphis fagi L.) on Fagus sylvatica (L.),Badania nad dynamiką liczebności, biologią i szkodliwością zdobniczki bukowej (Phyllaphis fagi L.) na buku zwyczajnym (Fagus sylvatica L.)
- Author
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Izabela Kot and Kmieć, K.
10. Physiological Response of Orchids to Mealybugs (Hemiptera: Pseudococcidae) Infestation
- Author
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Kmieć, K., Kot, I., Golan, K., Górska-Drabik, E., Łagowska, B., Rubinowska, K., and Michałek, W.
- Published
- 2019
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11. The Interplay of Nitric Oxide and Nitrosative Modifications in Maize: Implications for Aphid Herbivory and Drought Stress.
- Author
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Sytykiewicz H, Czerniewicz P, Ruszczyńska M, and Kmieć K
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- Animals, Gene Expression Regulation, Plant, Seedlings metabolism, Seedlings genetics, Plant Proteins metabolism, Plant Proteins genetics, Nitrosation, Zea mays metabolism, Zea mays genetics, Zea mays parasitology, Aphids physiology, Aphids metabolism, Nitric Oxide metabolism, Droughts, Herbivory, Stress, Physiological
- Abstract
Nitric oxide (NO) and other reactive nitrogen species (RNS) are considered to be signaling molecules in higher plants involved in the regulation of growth and development processes. However, the molecular mechanisms of their formation, removal, and participation in plant responses to adverse environmental stimuli remain largely unclear. Therefore, the aim of this study was to assess the influence of selected single stresses and combined stresses (i.e., Rhopalosiphum padi L. aphid infestation, drought, aphid infestation, and drought) and post-stress recovery on the contents of NO and peroxynitrite anion (ONOO
- ), as well as the levels of mRNA and protein nitration (i.e., the 8-nitroguanine and protein 3-nitrotyrosine amounts, respectively), in maize seedlings ( Zea mays L.). Moreover, the expression patterns of the two tested genes ( nos-ip , encoding nitric oxide synthase-interacting protein, and nr1 , encoding nitrate reductase 1) involved in NO metabolism in maize plants were quantified. We identified significant intervarietal, time-course, and stress-dependent differences in the levels of the quantified parameters. Under the investigated stress conditions, the aphid-resistant Waza cv. seedlings were characterized by a higher and earlier NO accumulation and mRNA nitration level and an increased expression of the two target genes ( nos-ip and nr1 ), compared to the aphid-susceptible Złota Karłowa cv. seedlings. Conversely, the Złota Karłowa plants responded with a greater elevation in the content of ONOO- and protein 3-nitrotyrosine than the Waza cv. plants The multifaceted role of NO and its derivatives in maize plants challenged by single and combined stresses, as well as during post-stress recovery, is discussed.- Published
- 2024
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12. Hemodynamic phenotypes in chronic kidney disease patients based on linear regression of blood pressure parameters.
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Cierpka-Kmieć K, Khursa R, and Hering D
- Abstract
Classic and non-classic cardiovascular (CV) risk factors accumulate in chronic kidney disease (CKD), contributing to vascular remodeling and hemodynamic abnormalities. This study aimed to determine hemodynamic phenotypes based on linear regression of blood pressure (BP) parameters in stage G3-G4 CKD patients at very high CV risk. 24-h ambulatory BP monitoring (ABPM), carotid-femoral pulse wave velocity (PWV) and central BP were obtained from 52 patients (aged 60 ± 11 years, BMI 30 ± 6 kg/m
2 ) with stage G3-G4 CKD (eGFR 44 ± 12 mL/min./1.73 m2 ). Linear BP regression coefficients were generated to determine hemodynamic phenotypes using ABPM data. Coexisting hypertension was present in 45 (86%) patients, out of whom 33 (73%) had BP controlled. 24-h mean systolic/diastolic BP was 128 ± 18/75 ± 12 mm Hg. Twenty-six patients demonstrated the harmonious (H) and 26 patients diastolic dysfunctional (D) hemodynamic phenotypes. eGFR was not significantly different between both phenotypes. Compared to phenotype H, patients with phenotype D were older (57 ± 11 vs. 63 ± 10 years, p = .04), had higher PWV (8.2 [7.3-10.3] vs. 9.7 [8.3-10.9] m/s, p = .02), ambulatory arterial stiffness index (AASI) (0.31 ± 0.1 vs. 0.40 ± 0.1, p = .02), systolic BP (128 [122-130] vs. 137 [130-150] mm Hg, p = .001) and systolic BP variability (BPV) (11.7 ± 2.3 vs. 15.7 ± 3.4 mm Hg, p < .0001). Our findings suggest that one in two patients with stage G3-G4 CKD demonstrates an unfavorable D hemodynamic phenotype based on a linear regression model, associated with higher PWV, AASI, systolic BP, and systolic BPV. Further studies are required to assess the clinical utility of hemodynamic phenotypes and whether the D phenotype may predict latent circulatory disorders and outcomes., (© 2024 The Author(s). The Journal of Clinical Hypertension published by Wiley Periodicals LLC.)- Published
- 2024
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13. Influence of Selected Indicators of Healthcare System Functioning Evaluation on the Health Result.
- Author
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Partyka O, Pajewska M, Czerw A, Sygit K, Kmieć K, Lyubinets O, Niemiec M, Kaczmarski M, Gąska I, Juszczyk G, Krzych-Fałta E, Banaś T, Kosior DA, Deptała A, Kotwas A, Bandurska E, Ciećko W, and Cipora E
- Subjects
- Humans, Health Expenditures, Delivery of Health Care, Health Services, Insurance, Health, Health Services Administration
- Abstract
Background: According to the World Health Organization's statistics, 7 of the 10 main causes of death in 2019 were noncommunicable diseases. Health indicators are measures used to evaluate public health system effectiveness and functioning. Monitoring mortality rates from leading causes, life expectancy and other health indicators is essential to address their causes and adapt health systems to react adequately. The aim of this study is to present the dependencies of selected health care indicators and health outcomes., Methods: Based on the literature review conducted, selected health indicators, along with healthcare system data, were analyzed using Pearson's r correlation. The analyses included data from the Organization for Economic Cooperation and Development (OECD) presented in statistics and the Health at a Glance 2021 report and data collected as part of the preparation of the Financing Global Health 2020 report by the Institute for Health Metrics and Evaluation., Results: Health system resources are linked to health outcomes. The number of medical consultations, the number of nurses per patient or the level of financing of services under general health insurance are related to life expectancy and deaths due to causes that could have been avoided or treated., Conclusions: Life expectancy is positively correlated with access to general health insurance and public expenditure on healthcare. There is a need for all countries to provide their citizens with broad access to healthcare services.
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- 2022
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14. The Sense of Coherence and Health Behavior of Men with Alcohol Addiction.
- Author
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Curyło M, Rynkiewicz-Andryśkiewicz M, Andryśkiewicz P, Mikos M, Lusina D, Raczkowski JW, Juszczyk G, Kotwas A, Sygit K, Kmieć K, Cipora E, Kaczmarski M, Banaś T, Strzępek Ł, Śliwczyński A, Krakowiak J, Świtalski J, Partyka O, and Czerw A
- Subjects
- Health Behavior, Humans, Male, Surveys and Questionnaires, Alcoholism, Sense of Coherence
- Abstract
Introduction: Alcohol dependence is one of the world's major health challenges. The salutogenic concept of health developed by Antonovsky focuses on the search for resources and factors supporting health. Its basic concept of the sense of coherence (SOC) focuses on strengthening the global orientation of the patient, and creating permanent internal resources that translate into the improvement of pro-health behavior, including the fight against alcoholism., Objective: The objective of this study was to determine the correlation between individual factors and the SOC as well as the influence of the SOC concept on pro-health behavior of people addicted to alcohol., Materials and Methods: The study group consisted of 110 men undergoing treatment in an addiction treatment ward. To check the level of the SOC, two standardized questionnaires, Antonovsky's "SOC-29 Life Orientation Questionnaire" and Juczyński's "Health Behaviour Inventory", were used. The correlation coefficient between the sociodemographic variables was checked using the Pearson's r test., Results: A positive correlation was found with the intensity of pro-health behaviors for three sociodemographic variables. In people aged 43-65 (r = 0.299; p = 0.030), people with primary/vocational education (r = 0.276; p = 0.015), and respondents living in rural areas (r = 0.303; p = 0.028) a greater SOC was associated with pro-health behaviors., Conclusions: Individuals addicted to alcohol are characterized by a low SOC and a low level of pro-health behaviors. Strengthening the internal level of the SOC can constitute an element of addiction therapy when introducing health education to prepare the patient for independent life in sobriety.
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- 2022
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15. Nutritional Treatment of Patients with Colorectal Cancer.
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Lewandowska A, Religioni U, Czerw A, Deptała A, Karakiewicz B, Partyka O, Pajewska M, Sygit K, Cipora E, Kmieć K, Augustynowicz A, Mękal D, Waszkiewicz M, Barańska A, Mináriková D, Minárik P, and Merks P
- Subjects
- Humans, Nutritional Status, Quality of Life, Colorectal Neoplasms therapy, Malnutrition etiology, Nutrition Therapy
- Abstract
Colorectal cancer is one of the most common cancers in Europe and the world. Cancer treatments have side effects and cause significant deterioration of the patient's nutritional status. Patient malnutrition may worsen the health condition and prevent the deliberate effects of the therapy. The aim of this review was to describe the available data about clinical nutrition in colorectal cancer patients. A large proportion of colorectal cancer patients suffer from malnutrition, which negatively affects the survival prognosis, quality of life, and oncological therapy. Therefore, monitoring nutritional status during the treatment is essential and can be used to arrange proper nutritional therapy to enhance patient responses, prevent side effects, and shorten recovery time. The principles of nutrition during anticancer therapy should mainly consider light and low-fat foods, the exclusion of lactose and gluten-containing foods in certain cases, or the introduction of special dietary products such as oral nutrition supplements and it should be tailored to patients' individual needs.
- Published
- 2022
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16. The Variation of Selected Physiological Parameters in Elm Leaves ( Ulmus glabra Huds.) Infested by Gall Inducing Aphids.
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Kmieć K, Kot I, Rubinowska K, Górska-Drabik E, Golan K, and Sytykiewicz H
- Abstract
Three aphid species, Eriosoma ulmi (L.), Colopha compressa (Koch) and Tetraneura ulmi (L.) induce distinct gall morphotypes on Ulmus glabra Huds.; opened and closed galls. Because the trophic relationship of aphids and their galls shows that throughout the gall formation aphids can elicit multiple physiological regulations, we evaluated the changes of hydrogen peroxide content (H
2 O2 ), cytoplasmic membrane condition, expressed as electrolyte leakage (EL ) and concentration of thiobarbituric acid reactive substances (TBARS), as well as, the activity of catalase (CAT), guaiacol peroxidase (GPX) and ascorbate peroxidase (APX) in gall tissues, as well as, in damaged and undamaged parts of galled leaves. All aphid species increased EL from gall tissues and significantly upregulated APX activity in galls and galled leaves. Alterations in H2 O2 and TBARS concentrations, as well as GPX and CAT activities, were aphid- and tissue-dependent. The development of pseudo- and closed galls on elm leaves did not have a clear effect on the direction and intensity of the host plant's physiological response. The different modes of changes in H2 O2 , TBARS, CAT and GPX were found in true galls of C. compressa and T. ulmi . Generally, physiological alterations in new plant tissues were quite different compared to other tissues and could be considered beneficial to galling aphids.- Published
- 2022
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17. Physical Activity and the Quality of Life of Female Students of Universities in Poland.
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Kotarska K, Paczyńska-Jędrycka M, Sygit K, Kmieć K, Czerw A, and Nowak MA
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- Adolescent, Adult, Cross-Sectional Studies, Exercise, Female, Humans, Poland, Students, Surveys and Questionnaires, Young Adult, Quality of Life, Universities
- Abstract
Physical activity increases human health potential and has an impact on achieving a higher quality of life in society. The aim of our research was to determine the relationship between a physically active lifestyle and the quality of life of female students in the context of demographic and social factors (major, age, marital status, professional activity). The research was conducted among a group of 285 women studying physical culture and social sciences in Poznań and Szczecin (Poland). Average age: 22.7 ± 4.90. The standardized World Health Organization Quality of Life-BREF (WHQOL-BREF) questionnaire was used to assess the quality of life of female students, and the original survey technique was used to study the lifestyle of people undertaking physical activity in the context of socio-demographic factors. Nonparametric statistics were applied in the analyses of the results. The effect size was calculated for each test: E
2 R for the Kruskal-Wallis H test, Glass rank biserial correlation (rg) for the Mann-Whitney U test, and Cramér's V for the χ2 test. The value of p ≤0.05 was assumed to be a significant difference. In the study, it was shown that a higher overall quality of life and health satisfaction, as well as better results in the physical, psychological, and environmental domains, were achieved by female students who assessed their lifestyle as physically active in comparison to those physically inactive. Higher scores of overall quality of life and satisfaction with health were found among female students of physical education and people participating in physical recreation, who also achieved better results in the environmental domain. Female students aged 23-25 had a higher quality of life in the physical, psychological, and social domains. Having a partner or spouse had a positive effect on the quality of life of female students defined by the social domain. A higher overall quality of life and satisfaction with health were characteristic of people who were employed. In the search of factors positively influencing the quality of life of society, it seems necessary to promote a physically active lifestyle among students. The observed differences in the quality of life and health satisfaction of female students of selected majors require targeted programs and interventions that improve the quality of their lives at various stages of their studies. Such activities increase the health potential of the individual and society, not only in the biological, but also psychosocial dimension.- Published
- 2021
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18. Expression of Thioredoxin/Thioredoxin Reductase System Genes in Aphid-Challenged Maize Seedlings.
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Sytykiewicz H, Łukasik I, Goławska S, Sprawka I, Goławski A, Sławianowska J, and Kmieć K
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- Animals, Oxidation-Reduction, Plant Diseases parasitology, Plant Proteins genetics, Seedlings genetics, Seedlings parasitology, Thioredoxin-Disulfide Reductase genetics, Zea mays genetics, Zea mays parasitology, Aphids physiology, Gene Expression Regulation, Plant, Plant Proteins metabolism, Seedlings metabolism, Thioredoxin-Disulfide Reductase metabolism, Thioredoxins metabolism, Zea mays metabolism
- Abstract
Thioredoxins (Trxs) and thioredoxin reductases (TrxRs) encompass a highly complex network involved in sustaining thiol-based redox homeostasis in plant tissues. The purpose of the study was to gain a new insight into transcriptional reprogramming of the several genes involved in functioning of Trx/TrxR system in maize ( Zea mays L.) seedlings, exposed to the bird cherry-oat aphid ( Rhopalosiphum padi L.) or the rose-grass aphid ( Metopolophium dirhodum Walk.) infestation. The biotests were performed on two maize genotypes (susceptible Złota Karłowa and relatively resistant Waza). The application of real-time qRT-PCR technique allowed to identify a molecular mechanism triggered in more resistant maize plants, linked to upregulation of thioredoxins-encoding genes ( Trx-f , Trx-h , Trx-m , Trx-x ) and thioredoxin reductase genes ( Ftr1 , Trxr2 ). Significant enhancement of TrxR activity in aphid-infested Waza seedlings was also demonstrated. Furthermore, we used an electrical penetration graph (EPG) recordings of M. dirhodum stylet activities in seedlings of the two studied maize varieties. Duration of phloem phase (E1 and E2 models) of rose-grass aphids was about three times longer while feeding in Waza plants, compared to Złota Karłowa cv. The role of activation of Trx/TrxR system in maintaining redox balance and counteracting oxidative-induced damages of macromolecules in aphid-stressed maize plants is discussed.
- Published
- 2020
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19. Poplar Tree Response to Feeding by the Petiole Gall Aphid Pemphigus spyrothecae Pass.
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Kot I and Kmieć K
- Abstract
Pemphigus spyrothecae Pass. which is a member of the subfamily Pemphiginae is one of the gall-inducing aphids that occurs on poplar trees. Phloem feeding of a founding mother on leaf petiole results in the formation of a new organ, i.e., the spiral gall. This study documents aphid development inside the galls during the growing season and the effect of their feeding on leaf architecture and physiology of the host plant. In particular, leaf length, width, and area were measured, as well as hydrogen peroxide (H
2 O2 ) content, electrolyte leakage (EL ), malondialdehyde (MDA) concentration, and the activity of ascorbate (APX) and guaiacol peroxidase (GPX) were determined in galls and galled leaves. The presence of petiole galls significantly decreased the length, width, and leaf area. Aphid activity increased H2 O2 concentration in galls and EL from galls and leaf tissues, which was accompanied by a strong decrease in MDA content and both peroxidase activities, especially in gall tissues. It can be suggested that P. spyrothecae can manipulate physiological machinery of the host plant for its own benefit., Competing Interests: The authors declare no conflict of interest.- Published
- 2020
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20. Tachycardia: The hidden cardiovascular risk factor in uncomplicated arterial hypertension.
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Cierpka-Kmieć K and Hering D
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- Heart Disease Risk Factors, Humans, Risk Factors, Tachycardia, Cardiovascular Diseases, Hypertension diagnosis, Hypertension drug therapy, Hypertension epidemiology
- Abstract
Early detection and management of elevated blood pressure is crucial in reducing the burden of cardiovascular disease (CVD). The importance of an absolute risk assessment and patient risk stratification has been highlighted in the European hypertension guidelines since 2003. Amongst numerous risk factors influencing patient prognosis, elevated heart rate (HR) has been indicated as important predictor of future risk of hypertension, coronary heart disease, sudden cardiac death, heart failure, CVD, stroke, total cancer and mortality. Given that resting HR can be easily determined in clinical practice and modified by lifestyle changes as well as beta-blocker therapy, it seems reasonable that lowering resting HR should be a potential target to reduce disease burden and premature mortality. However, there is a lack of outcome studies of HR lowering in tachycardia-related hypertension. This review outlines the underlying mechanisms of early course hypertension pathophysiology with the critical role of the sympathetic nervous system activation, the prognostic significance of fast HR and the mechanistic rationale for the use of non-pharmacological approaches and/or highly long-acting cardioselective beta-blockers with some consideration given to betaxolol properties.
- Published
- 2020
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21. Physiological Response of Basil Plants to Twospotted Spider Mite (Acari: Tetranychidae) Infestation.
- Author
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Golan K, Kot I, Górska-Drabik E, Jurado IG, Kmieć K, and Łagowska B
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- Animals, Hydrogen Peroxide, Plant Leaves, Mites, Ocimum basilicum, Tetranychidae
- Abstract
The induction of plant resistance against pests is considered a potential method of controlling mite infestation as it restricts the use of chemical pesticides in herbal crops. Our goal was to investigate whether plant physiological response to mite feeding varied depending on basil cultivar and/or duration of mite infestation. The effect of plant acceptance, mite mortality rate, and changes in physiological parameters: malondialdehyde content (MDA), hydrogen peroxide (H2O2) concentration, and antioxidant enzyme activities, including guaiacol peroxidase (GPX) and catalase (CAT) were examined in this study. Tetranychus urticae Koch (Acari: Tetranychidae) infestation induced oxidative stress in three Ocimum basilicum L. cultivars: 'Sweet basil,' 'Purpurascens,' and 'Fino Verde.' The analysis of mite behavior and alteration in metabolic plant profiles showed different sensitivities of basil cultivars to biotic stress that were dependent on the cultivar and duration of infestation. All basil plants were suitable as host plants for T. urticae, but they varied in the level of susceptibility to mite feeding. O. basilicum 'Fino Verde' was the most suitable host for the twospotted spider mite. In turn, O. basilicum 'Purpurascens' was characterized by the lowest level of susceptibility to T. urticae feeding. The lowest acceptance, the highest mortality of twospotted spider mite individuals as well as decreased levels of H2O2 and MDA, significantly increased GPX activity and low level of CAT activity were recorded in O. basilicum 'Purpurascens' leaves. Research on plant responses to biotic stress can inform breeding cultivars resistant to arthropod attack., (© The Author(s) 2019. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2019
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22. Transcriptional profiling of catalase genes in juglone-treated seeds of maize (Zea mays L.) and wheat (Triticum aestivum L.).
- Author
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Sytykiewicz H, Kozak A, Leszczyński B, Sempruch C, Łukasik I, Sprawka I, Kmieć K, Kurowska M, Kopczyńska A, and Czerniewicz P
- Subjects
- Catalase biosynthesis, Enzyme Induction drug effects, Gene Expression Regulation, Plant drug effects, Germination drug effects, Hydrogen Peroxide metabolism, Isoenzymes, Plant Proteins biosynthesis, Seeds enzymology, Seeds genetics, Triticum enzymology, Triticum genetics, Zea mays enzymology, Zea mays genetics, Catalase genetics, Gene Expression Profiling methods, Naphthoquinones pharmacology, Plant Proteins genetics, Seeds drug effects, Transcriptome drug effects, Triticum drug effects, Zea mays drug effects
- Abstract
The major aim of the present study was to investigate the influence of juglone (JU; 5-hydroxy-1,4-naphthoquinone) treatments on the expression level of Cat1, Cat2 and Cat3 genes, encoding the respective catalase isozymes in maize (Zea mays L.) and wheat (Triticum aestivum L.) seeds. In parallel, germination efficiency, catalase (CAT) activity and hydrogen peroxide (H
2 O2 ) content in juglone-exposed cereal seeds were assessed. Juglone applications significantly stimulated abundance of three target catalase transcripts as well as induced CAT activity and generation of H2 O2 in both maize and wheat kernels. Furthermore, germination process of juglone-affected maize seeds was more severe suppressed than in case of wheat kernels. The role of juglone in triggering the oxidative stress as well as antioxidative responses in seeds of the studied model cereal species are discussed.- Published
- 2018
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23. Early results of revision acetabular cup using antiprotrusio reconstruction rings and allografts.
- Author
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Kmieć K, Dorman T, Andrzej G, Synder M, Kozłowski P, and Sibiński M
- Abstract
Background: Hip arthroplasty is one of the most frequently performed orthopedic procedures with high scores of success while its most common complication is aseptic loosening of the acetabular component, which may result from host bone loss or even from pelvis discontinuity. The purpose of the study was to evaluate results in patients after revision acetabular arthroplasty with reconstruction rings and allografts., Materials and Methods: Retrospective data was collected from 69 revisions of acetabular components, performed in a group of 69 treated patients (the mean age 65.1 years). Before surgery, the patients had bone defects of type IIb (n = 5), IIc (n = 20), IIIa (n = 27) or IIIb (n = 17), according to Paprosky et al., Results: The mean followup period of the patients was 7.2 years (range 3-19 years). A Kaplan-Meier analysis showed that a 3- and 10 year survival rate was 92.8% and 84.8% respectively, using further revision for any reason of the acetabular device as an end point. Eight patients revealed implant related complications. Four patients presented with ring loosening, one with a loose acetabular polyethylene cup, two hips demonstrated recurrent dislocations and one patient was with deep infection. Regarding the remaining 61 patients without re-revision surgery, the mean Harris hip score improved from 30.5 to 73.8 points., Conclusion: A modified, antiprotrusion cage provides an acceptable survival rate and radiological results, but complications could still be expected. It seems that the observed massive bone loss with pelvic discontinuity and an insufficient fixation of the cage to the ischium may result in implant loosening. Stable fixation of the ischial ring flange with screws is an essential condition to expect a good outcome.
- Published
- 2015
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24. Metallographic evaluation of hip joint implants wear and electrochemical implants potential.
- Author
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Kmieć K, Sibinski M, Synder M, Drobniewski M, and Kozłowski P
- Subjects
- Electrochemistry, Female, Humans, Infant, Male, Mechanical Phenomena, Microscopy, Electron, Scanning, Prosthesis Design, Reoperation, Foreign Bodies etiology, Hip Prosthesis adverse effects, Prosthesis Failure adverse effects, Titanium analysis
- Abstract
We performed metallographic evaluations of implants, removed during revision hip arthroplasty. The implants were evaluated for electrochemical potentials and the presence of wear products on the implants surface. A total of 50 patients (50 hips) underwent revision hip arthroplasty during the years 2007-2009 for aseptic loosening. The mean follow-up from primary hip replacement to revision was 10.1 years (from six months to 17 years). All hip joint implants removed during the revision arthroplasty were submitted to metallographic analysis and all heads were submitted to analysis under a scanning microscope. All polyethylene (PE) cups and inserts showed numerous features of wear (friction wear, plastic deformation and creeping, fatigue wear and degradation), six PE cups were broken. In six ceramic cups, only friction wear features were found; one of them was mechanically broken. In all heads articulating on PE not one had any mechanical damage. Heads of ceramic implants in ceramic-ceramic articulation undergo abrasive wear. None of the studied stems (cemented or uncemented) revealed any features of wear. Areas of titanium crystals (formed by electrolytic sedimentation of metals) were macroscopically identified on the sliding surface of six heads that was confirmed by chemical composition and scanning microscope.In the course of prosthesis use, wear products are produced and transferred onto the sliding surfaces of implant heads and cups via ways other than purely mechanical contact. It has been confirmed that metals used for implant construction, make galvanic cells with different electrochemical potentials.
- Published
- 2014
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25. Metal debris concentrations in soft tissues adjacent to loosened femoral stems is higher in uncemented than cemented implants.
- Author
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Kmieć K, Synder M, Kozłowski P, Drobniewski M, and Sibiński M
- Subjects
- Adult, Aged, Aged, 80 and over, Arthroplasty, Replacement, Hip adverse effects, Female, Humans, Male, Middle Aged, Prosthesis Design, Reoperation, Time Factors, Treatment Outcome, Young Adult, Arthroplasty, Replacement, Hip instrumentation, Bone Cements therapeutic use, Femur surgery, Hip Prosthesis, Metals analysis, Prosthesis Failure
- Abstract
Background: There are still many questions related to aseptic femoral stem loosening. Systemic and local immune responses to the implanted "foreign body" is one of the reasons for loosening. The purpose of the study was to measure metal ion concentration (Ti, Co, Cr, Mo, Ni, Al) around loosened femoral stems and compare their levels around uncemented and cemented implants., Methods: This paper reports 50 hips operated for isolated stem loosening, in 50 patients at the mean age of 57 years (from 21 to 87). There were 25 cemented (Co,Cr29,Mo,Ni) and 25 uncemented (Ti, Al) stems. The mean follow-up from primary hip replacement to revision was 10.1 years (from 0.5 to 17). During the procedure, scar tissue around the stem was taken for analysis of metal ions., Results: The concentrations of titanium and aluminium in soft tissues around uncemented loosened stems were higher than cemented ones (p < 0.001, p < 0.001 respectively). However, no statistically significant differences were observed between both types of stems in terms of ions of the metal of which cemented implants had been made of (Co, Cr, Mo, Ni)., Conclusions: In soft tissue around a loosened stem, the concentrations of metal ions from implants are much higher in case of uncemented stems than of cemented ones. Metal ions from vitalium femoral heads were found around uncemented stems in similar values to cemented streams.
- Published
- 2014
- Full Text
- View/download PDF
26. Parasitoid complex associated with the overwintering generation of Swammerdamia pyrella (Lepidoptera: Yponomeutidae) in Poland.
- Author
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Górska-Drabik E, Kot I, Golan K, and Kmieć K
- Subjects
- Animals, Larva growth & development, Larva parasitology, Larva physiology, Moths growth & development, Pest Control, Biological, Poland, Seasons, Wasps growth & development, Host-Parasite Interactions, Moths parasitology, Wasps physiology
- Abstract
The study was conducted on fruit trees where bands of corrugated cardboard were attached around the trunks of the trees, which were used to catch the larvae of overwintering generation of the rufous-tipped swammerdamia moth, Swammerdamia pyrella (Villers) (Lepidoptera: Yponomeutidae). Twenty-five species of parasitic Hymenoptera have been described from S. pyrella in Poland including the report in this article of seven species belonging to the family of Ichneumonidae (three species) and superfamily Chalcidoidea (four species). The parasitoids Gelis agilis F. (Ichneumonidae), Chrysocharis aquilegiae (Erdös) (Eulophidae), Catolaccus ater (Ratzeburg) (Pteromalidae), and Eupelmus urozonus (Dalman) (Eupelmidae) had not been reported from the host before. Triclistus pallipes Holmgren (Ichneumonidae), Dibrachys cavus Walker (Pteromalidae) had the greatest effect on the natural regulation of S. pyrella population. Parasitization for the wintering cocoons of S. pyrella changed each year, but it was high throughout the study. The contribution of secondary parasitoids was much higher than primary parasitoids., (© The Author 2014. Published by Oxford University Press on behalf of the Entomological Society of America.)
- Published
- 2014
- Full Text
- View/download PDF
27. Shelf acetabuloplasty in the treatment of severe Legg-Calvé-Perthes disease: good outcomes at midterm follow-up.
- Author
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Grzegorzewski A, Synder M, Kmieć K, Krajewski K, Polguj M, and Sibiński M
- Subjects
- Child, Child, Preschool, Epiphyses pathology, Female, Femur Head pathology, Follow-Up Studies, Humans, Legg-Calve-Perthes Disease pathology, Male, Range of Motion, Articular, Treatment Outcome, Epiphyses surgery, Femur Head surgery, Legg-Calve-Perthes Disease surgery
- Abstract
The aim of the study was to retrospectively review results of operative treatment for coverage deficit of femoral head in children with severe epiphysis displacement in Legg-Calvé-Perthes (LCP) disease. The material included 23 shelf acetabuloplasty procedures for LCP disease. The average age at diagnosis was 8.1 years (range 4-12). Mean follow-up was 5.8 years (range from 2.2 to 11.2 years). Mean Reimer's index decreased statistically significantly from a mean of 32% before surgery to 10.0% at the last follow-up (P < 0.00001). The mean Wiberg center-edge angle increased also statistically significantly from a mean of 17.3° before procedure to 32.3° at the last follow-up (P < 0.00001). According to the Stulberg classification, type I was observed in 2, type II in 13, type III in 6, and type IV in 2 hips. There were no differences in the range of motion or leg length discrepancy in preoperative and postoperative standing. Partial, not significant, bone graft resorption was noted in 6 cases in the first 6-9 months after surgery. To conclude, shelf acetabuloplasty allows achieving good midterm results in the treatment of severe stages of LCP disease. The procedure improves coverage of femoral head and allows its remodelling.
- Published
- 2013
- Full Text
- View/download PDF
28. [Clinical and metallographic evaluation of the causes of mechanical loosening of revision baskets Recon Ring--description of 3 cases].
- Author
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Kmieć K, Sedzicki M, Dorman T, Sibiński M, Synder M, and Kozłowski P
- Subjects
- Acetabulum diagnostic imaging, Aged, Arthroplasty, Replacement, Hip instrumentation, Female, Humans, Internal Fixators adverse effects, Male, Middle Aged, Prosthesis Design, Radiography, Reoperation methods, Treatment Outcome, Acetabulum surgery, Arthroplasty, Replacement, Hip adverse effects, Equipment Failure Analysis, Hip Prosthesis adverse effects, Prosthesis Failure etiology
- Abstract
Aim of this study is to assess the causes of mechanical loosening of revision Recon Ring baskets (Aesculap / BBrown, Germany). This analysis was done by assessing the circumstances of baskets loosening of revision in 3 patients. Intraoperative images and radiographs of patients with these clinical complications were analyzed, and removed damaged bins and bolts of revision metallographic expertise. It was found that the most likely cause mechanical damage to the implant was originally unstable or re-fixing their ischial part, causing movable canopy closer to the basket is balanced by the screws and in turn causing fracture or bending arms, and follow-up baskets of hip bone loss. Our observations suggest that the most important is proper attachment of acetabular basket, especially his arm sciatic.
- Published
- 2011
29. [Hip revision arthroplasty in massive bone loss of acetabulum with the use of reinforcement ring].
- Author
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Dorman T, Kmieć K, Pogonowicz E, Sibiński M, Synder M, and Kozłowski P
- Subjects
- Acetabulum diagnostic imaging, Adult, Aged, Aged, 80 and over, Female, Follow-Up Studies, Humans, Internal Fixators, Male, Middle Aged, Postoperative Complications diagnostic imaging, Prosthesis Failure, Radiography, Reoperation methods, Treatment Outcome, Acetabulum surgery, Arthroplasty, Replacement, Hip methods, Bone Transplantation methods, Hip Prosthesis, Osteolysis surgery, Postoperative Complications surgery
- Abstract
The aim of the study was the assessment of results after acetabular revision arthtoplasty with the use of reinforcement ring ReconShell (BBrown - Aesculap) and homogenous bone grafts. There were 49 patients in the study (42 women and 7 men) in the age from 30 to 88 years. The follow-up period ranged from 4 to 48 months. Before operation the mean Harris hip score was 31.14 and at last follow-up 71.64 points. Aseptic loosening of reconstruction ring was found in 3 patients. During next revision good integration of bone grafts, that were implanted into acetabulum at previous operation was found. In one hip revision of loose polietylen cup was performed. Three patient had early dislocation of hip endoprothesis, that were treated successfully in abduction casts. Next 2 patients had re-revision performed for recurrent dislocations. One patient had implants removal for septic loosening. Prolonged wound healing was noticed in 5 patients. Two patients had temporary and one permanent common peroneal nerve palsy. Two patients had temporary femoral nerve palsy. The use of reconstruction rings in massive bone loss of the acetabulum after cup loosening gives satisfactory clinical results. After the procedure patients have stabile joint that allows for weight bearing. Despite relatively high number of complications (most of which are temporary) this procedure is worth recommending.
- Published
- 2011
30. Cementless hip joint alloplasty complicated by intraoperative fracture of the femoral bone.
- Author
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Dorman T, Sibiński M, Kmieć K, Bira M, Borowski A, and Synder M
- Subjects
- Adult, Arthroplasty, Replacement, Hip instrumentation, Arthroplasty, Replacement, Hip methods, Female, Femoral Fractures diagnostic imaging, Femoral Fractures etiology, Follow-Up Studies, Humans, Intraoperative Complications etiology, Intraoperative Period, Male, Middle Aged, Poland, Prosthesis Design, Radiography, Retrospective Studies, Treatment Outcome, Young Adult, Arthroplasty, Replacement, Hip adverse effects, Femoral Fractures surgery, Fracture Fixation, Internal methods, Hip Prosthesis adverse effects, Intraoperative Complications surgery
- Abstract
Background: The aim of the study was to analyse the outcomes of hip replacement complicated by intraoperative femoral fractures and to analyse their effective management., Materials and Methods: The medical records of 43 cases of intraoperative femoral fractures (1.4% of all hip replacements) were retrospectively reviewed. The patient group included 29 females. Patients' age ranged from 20 to 66 years (mean age: 48.4 years). Follow-up duration ranged from 8 to 89 months (mean duration: 44 months)., Results: There were 13 fractures of the greater trochanter, 21 fractures of the lesser trochanter involving the calcar, 7 at the implant stem level, and two below the implant stem. In 3 cases, the fracture was treated with a revision stem, with cerclage used in 17 other cases. In the remaining cases, the fractures were stable and did not require any internal fixation. Eighteen patients had very good final results, 19 had good and 6, fair results, according to Merle D'Aubigne- Postel's classification in Charnley's modification. None of our patients demonstrated evidence of stem loosening at the final follow-up., Conclusions: Unstable intraoperative femoral fractures during a hip replacement procedure are rare and occur mostly in patients with post-dysplastic hips with a narrow intramedullary canal. In cases of stable fractures of the trochanter and calcar region, 12 weeks of partial weight bearing without additional immobilization is a sufficient approach. The final results are satisfactory in most cases of intraoperative femoral fractures.
- Published
- 2010
31. [Coronary disease in the past. An attempt at evaluating the dissertation by Jan Cenner "De angor pectoris" (1820) in the context of contemporary knowledge].
- Author
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Skalski JH, Skalska A, Turczyński B, and Kmieć K
- Subjects
- Angina Pectoris physiopathology, History, 19th Century, Humans, Poland, Academic Dissertations as Topic history, Angina Pectoris history, Cardiology history
- Abstract
Following an abbreviated historical review of literature related to angina pectoris spanning the period from olden days to the beginning of the XIX th century, this paper analyses Jan Cenner's doctoral dissertation entitled "Dissertation inauguralis medica de angor pectoris", written in Cracow, Poland in 1820. A conciliation of the information regarding coronary artery disease with the current state of medical understanding is made in a tabular form and an attempt at an assessment of treatment rules (including prevention, general non-specific therapy, local treatment, dietary management and the use of pharmacological agents) according to updated medical criteria follows. The authors' goal is an objective evaluation of the real scientific value of Cenner's work in light of nearly two centuries of progress in medical knowledge. Emphasis is placed on those diagnostic findings and therapeutic paths relating to coronary artery disease that are currently used in medical practice.
- Published
- 2003
32. [Diagnostic problems with Borrelia burgdorferi infection in children].
- Author
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Andrzejewski A, Woźniakowska-Gesicka T, Wiśniewska-Ligier M, and Kmieć K
- Subjects
- Diagnosis, Differential, Humans, Lyme Disease epidemiology, Lyme Disease microbiology, Poland epidemiology, Borrelia burgdorferi isolation & purification, Lyme Disease diagnosis
- Abstract
Lyme borreliosis has become a serious diagnostic and therapeutic problem of modern medicine. The occurrence of the disease in Europe, and also in Poland, has recently increased. Diagnostic problems with Borrelia burgdorferi infection result from non-characteristic course of the disease in children, without the 1 st stage of the disease (erythema migrans), negative history forwards tick bite, lack of seasonal changes in occurrence and difficulties with interpretation of serological tests results. Direct laboratory investigations are also of little relevance.
- Published
- 2003
33. [Clinical course of borreliosis in children].
- Author
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Andrzejewski A, Woźniakowska-Gesicka T, Kmieć K, and Sass-Just M
- Subjects
- Adolescent, Child, Child, Preschool, Female, Fever epidemiology, Fever microbiology, Headache epidemiology, Headache microbiology, Humans, Incidence, Lyme Disease epidemiology, Male, Meningitis, Bacterial epidemiology, Meningitis, Bacterial microbiology, Peripheral Nervous System Diseases epidemiology, Peripheral Nervous System Diseases microbiology, Poland epidemiology, Risk Factors, Seasons, Borrelia burgdorferi Group isolation & purification, Lyme Disease diagnosis, Lyme Disease microbiology
- Abstract
Clinical picture of Borrelia burgdorferi infection has been presented in 45 children, aged 2-16 years from Łódź region. The analysis showed significant domination of cases with affected central and peripheral nervous system (44.4%) and rather unspecific symptoms such as: fever (20%) or headache (13.3%). Peripheral cranial nerves paralysis and symptoms of cerebrospinal meningitis dominated among children with neuroborreliosis. Unlike descriptions concerning adults, majority of the observed symptoms were changes characteristic for I and II stage of the disease. Dermatosis was found only in 1 child and symptoms of arthritis in 2 of them. Contact with tick was stated in 52% of the analysed children. Incidence of the disease occurred throughout the whole year, more frequently in summer and autumn months.
- Published
- 2002
34. [Congenital toxoplasmosis in own studies].
- Author
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Kmieć K, Woźniakowska-Gesicka T, and Andrzejewski A
- Subjects
- Animals, Antibodies, Protozoan blood, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Pregnancy, Toxoplasma, Toxoplasmosis prevention & control, Immunoglobulin M blood, Neonatal Screening, Pregnancy Complications, Parasitic diagnosis, Pregnancy Complications, Parasitic prevention & control, Toxoplasmosis, Congenital diagnosis, Toxoplasmosis, Congenital prevention & control
- Abstract
Clinical picture of congenital Toxoplasma gondii has been presented in 20 children. The infection was diagnosed in 18 children in the first and in 2 children in the sixth month of life. Clinical symptoms were observed in as many as 12 children. The most frequent symptoms were those concerning central nervous system, organ of vision in the form of hydrocephalus, spastic paresis, epilepsy, intracranial calcification, choroiditis, retinitis and vision impairment. The presented analysis indicates an urgent need of introduction of screening in pregnant women and infants and widespreading of prophylactic activity aiming at raising awareness of the existing threat of T. gondii infection.
- Published
- 2001
35. [Peripheral blood lymphocytes T gammadelta in children with acute acquired toxoplasmosis].
- Author
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Kmieć K and Woźniakowska-Gesicka T
- Subjects
- Acute Disease, Adolescent, Animals, Child, Child, Preschool, Female, Humans, Male, Reference Values, Receptors, Antigen, T-Cell, gamma-delta analysis, T-Lymphocyte Subsets immunology, Toxoplasma immunology, Toxoplasmosis diagnosis, Toxoplasmosis immunology
- Abstract
The aim of the study was to determine the percentage participation of lymphocytes CD3TCRgammadelta in peripheral blood of children with acute toxoplasmosis. The study compromised 30 children aged 2-14 years. Increase of the percentage of CD3TCR gammadelta cells was observed in the group of children with clinical symptoms of toxoplasmosis (mean value 5.7%) in relation to the comparative group (mean 4.4%), but in 12 children (40%) the mean value was 8.1%. Toxoplasma gondii infection produces a strong signal for activation of cells with gammadelta receptors. Examination of CD3TCRgammadelta cells may be helpful in the diagnosis of the acute phase of T. gondii infection.
- Published
- 2001
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