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2. Evaluation of Public Health Contact Tracing for Mpox Among Gay, Bisexual, and Other Men Who Have Sex With Men—10 US Jurisdictions, May 17–July 31, 2022

Author

Cope, Anna Barry, primary, Kirkcaldy, Robert D., additional, Weidle, Paul J., additional, Jackson, David A., additional, Laramee, Nicholas, additional, Weber, Robyn, additional, Rowse, Julia, additional, Mangla, Anil, additional, Fox, Brian, additional, Saunders, Katharine E., additional, Taniguchi, Kristen, additional, Usagawa, Lauren, additional, Cahill, Megan E., additional, Harrington, Pauline, additional, Ricketts, Erin K., additional, Harbi, Khalil, additional, Malec, Lenka, additional, Templin, Tingting Gu, additional, Drociuk, Dan, additional, Hannibal, Terri, additional, Klos, Rachel, additional, and Bernstein, Kyle T., additional

Published
2023
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3. Public Health Surveillance and Reporting for Human Toxoplasmosis--Six States, 2021

Author

McCall, Jayden, Rothfeldt, Laura, Giesbrecht, Kelly, Hunt, Amanda, Bauck, Leah, Scheftel, Joni, Birn, Rachael, Buss, Bryan, Schroeder, Betsy, Haupt, Thomas E., Klos, Rachel, and Straily, Anne

Subjects
Diseases, Surveys, Toxoplasmosis -- Surveys, Public health -- Surveys, Infection -- Surveys, Zoonoses -- Surveys
Abstract

Toxoplasmosis is caused by infection with the zoonotic parasite Toxoplasma gondii. Although disease tends to be mild (e.g., self-limiting influenza-like symptoms) or asymptomatic in immunocompetent persons, toxoplasmosis is more severe [...]

Published
2022

5. Outbreak of Multidrug-Resistant Salmonella Heidelberg Infections Linked to Dairy Calf Exposure, United States, 2015–2018

Author

Nichols, Megin, primary, Gollarza, Lauren, additional, Sockett, Donald, additional, Aulik, Nicole, additional, Patton, Elisabeth, additional, Francois Watkins, Louise K., additional, Gambino-Shirley, Kelly J., additional, Folster, Jason P., additional, Chen, Jessica C., additional, Tagg, Kaitlin A., additional, Stapleton, Gregory Sean, additional, Trees, Eija, additional, Ellison, Zachary, additional, Lombard, Jason, additional, Morningstar-Shaw, Brenda, additional, Schlater, Linda, additional, Elbadawi, Lina, additional, and Klos, Rachel, additional

Published
2022
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7. One Health Investigation of SARS-CoV-2 Infection and Seropositivity among Pets in Households with Confirmed Human COVID-19 Cases—Utah and Wisconsin, 2020

Author

Goryoka, Grace W., primary, Cossaboom, Caitlin M., additional, Gharpure, Radhika, additional, Dawson, Patrick, additional, Tansey, Cassandra, additional, Rossow, John, additional, Mrotz, Victoria, additional, Rooney, Jane, additional, Torchetti, Mia, additional, Loiacono, Christina M., additional, Killian, Mary L., additional, Jenkins-Moore, Melinda, additional, Lim, Ailam, additional, Poulsen, Keith, additional, Christensen, Dan, additional, Sweet, Emma, additional, Peterson, Dallin, additional, Sangster, Anna L., additional, Young, Erin L., additional, Oakeson, Kelly F., additional, Taylor, Dean, additional, Price, Amanda, additional, Kiphibane, Tair, additional, Klos, Rachel, additional, Konkle, Darlene, additional, Bhattacharyya, Sanjib, additional, Dasu, Trivikram, additional, Chu, Victoria T., additional, Lewis, Nathaniel M., additional, Queen, Krista, additional, Zhang, Jing, additional, Uehara, Anna, additional, Dietrich, Elizabeth A., additional, Tong, Suxiang, additional, Kirking, Hannah L., additional, Doty, Jeffrey B., additional, Murrell, Laura S., additional, Spengler, Jessica R., additional, Straily, Anne, additional, Wallace, Ryan, additional, and Barton Behravesh, Casey, additional

Published
2021
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8. Human-to-Cattle Mycobacterium tuberculosis Complex Transmission in the United States

Author

Lombard, Jason E., primary, Patton, Elisabeth A., additional, Gibbons-Burgener, Suzanne N., additional, Klos, Rachel F., additional, Tans-Kersten, Julie L., additional, Carlson, Beth W., additional, Keller, Susan J., additional, Pritschet, Delora J., additional, Rollo, Susan, additional, Dutcher, Tracey V., additional, Young, Cris A., additional, Hench, William C., additional, Thacker, Tyler C., additional, Perea, Claudia, additional, Lehmkuhl, Aaron D., additional, and Robbe-Austerman, Suelee, additional

Published
2021
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9. Enhanced contact investigations for nine early travel-related cases of SARS-CoV-2 in the United States

Author

Burke, Rachel M., primary, Balter, Sharon, additional, Barnes, Emily, additional, Barry, Vaughn, additional, Bartlett, Karri, additional, Beer, Karlyn D., additional, Benowitz, Isaac, additional, Biggs, Holly M., additional, Bruce, Hollianne, additional, Bryant-Genevier, Jonathan, additional, Cates, Jordan, additional, Chatham-Stephens, Kevin, additional, Chea, Nora, additional, Chiou, Howard, additional, Christiansen, Demian, additional, Chu, Victoria T., additional, Clark, Shauna, additional, Cody, Sara H., additional, Cohen, Max, additional, Conners, Erin E., additional, Dasari, Vishal, additional, Dawson, Patrick, additional, DeSalvo, Traci, additional, Donahue, Matthew, additional, Dratch, Alissa, additional, Duca, Lindsey, additional, Duchin, Jeffrey, additional, Dyal, Jonathan W., additional, Feldstein, Leora R., additional, Fenstersheib, Marty, additional, Fischer, Marc, additional, Fisher, Rebecca, additional, Foo, Chelsea, additional, Freeman-Ponder, Brandi, additional, Fry, Alicia M., additional, Gant, Jessica, additional, Gautom, Romesh, additional, Ghinai, Isaac, additional, Gounder, Prabhu, additional, Grigg, Cheri T., additional, Gunzenhauser, Jeffrey, additional, Hall, Aron J., additional, Han, George S., additional, Haupt, Thomas, additional, Holshue, Michelle, additional, Hunter, Jennifer, additional, Ibrahim, Mireille B., additional, Jacobs, Max W., additional, Jarashow, M. Claire, additional, Joshi, Kiran, additional, Kamali, Talar, additional, Kawakami, Vance, additional, Kim, Moon, additional, Kirking, Hannah L., additional, Kita-Yarbro, Amanda, additional, Klos, Rachel, additional, Kobayashi, Miwako, additional, Kocharian, Anna, additional, Lang, Misty, additional, Layden, Jennifer, additional, Leidman, Eva, additional, Lindquist, Scott, additional, Lindstrom, Stephen, additional, Link-Gelles, Ruth, additional, Marlow, Mariel, additional, Mattison, Claire P., additional, McClung, Nancy, additional, McPherson, Tristan D., additional, Mello, Lynn, additional, Midgley, Claire M., additional, Novosad, Shannon, additional, Patel, Megan T., additional, Pettrone, Kristen, additional, Pillai, Satish K., additional, Pray, Ian W., additional, Reese, Heather E., additional, Rhodes, Heather, additional, Robinson, Susan, additional, Rolfes, Melissa, additional, Routh, Janell, additional, Rubin, Rachel, additional, Rudman, Sarah L., additional, Russell, Denny, additional, Scott, Sarah, additional, Shetty, Varun, additional, Smith-Jeffcoat, Sarah E., additional, Soda, Elizabeth A., additional, Spitters, Christopher, additional, Stierman, Bryan, additional, Sunenshine, Rebecca, additional, Terashita, Dawn, additional, Traub, Elizabeth, additional, Vahey, Grace M., additional, Verani, Jennifer R., additional, Wallace, Megan, additional, Westercamp, Matthew, additional, Wortham, Jonathan, additional, Xie, Amy, additional, Yousaf, Anna, additional, and Zahn, Matthew, additional

Published
2020
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10. Outbreak of human infections with uncommonSalmonellaserotypes linked to pet bearded dragons, 2012–2014

Author

Kiebler, Craig A., primary, Bottichio, Lyndsay, additional, Simmons, Latoya, additional, Basler, Colin, additional, Klos, Rachel, additional, Gurfield, Nikos, additional, Roberts, Elizabeth, additional, Kimura, Akiko, additional, Lewis, Linda S., additional, Bird, Kiyomi, additional, Stiles, Felicia, additional, Schlater, Linda K., additional, Lantz, Kristina, additional, Edling, Thomas, additional, and Barton Behravesh, Casey, additional

Published
2020
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12. Outbreak of human infections with uncommon Salmonella serotypes linked to pet bearded dragons, 2012–2014.

Author

Kiebler, Craig A., Bottichio, Lyndsay, Simmons, Latoya, Basler, Colin, Klos, Rachel, Gurfield, Nikos, Roberts, Elizabeth, Kimura, Akiko, Lewis, Linda S., Bird, Kiyomi, Stiles, Felicia, Schlater, Linda K., Lantz, Kristina, Edling, Thomas, and Barton Behravesh, Casey

Subjects
SALMONELLA diseases, AGAMIDAE, SEROTYPES, DRAGONS, PET industry, PET care
Abstract

Reptiles are one of the fastest growing sectors in the United States pet industry. Reptile‐associated salmonellosis (RAS) continues to be an important public health problem, especially among children. We investigated an outbreak of human Salmonella infections resulting from serotypes Cotham and Kisarawe, predominately occurring among children. An outbreak of illnesses was identified in persons with exposure to pet bearded dragon lizards. Human and animal health officials, in cooperation with the pet industry, conducted epidemiologic, traceback and laboratory investigations. Onsite sampling was conducted at two US breeding facilities, one foreign breeding facility, and a large pet retail chain. A total of 166 patients in 36 states were identified with illness onset dates from 02/2012–06/2014. The median patient age was 3 years (range, <1–79 years), 57% were aged ≤5 years, and 37% were aged ≤1 year. Forty‐four patients (37%) were hospitalized, predominantly children. Sampling at breeding facilities and a national pet store chain resulted in isolation of outbreak serotypes at each facility; isolation proportions ranged from 2%–24% of samples collected at each facility.Epidemiologic, microbiologic and traceback evidence linked an outbreak of uncommon Salmonella serotypes to contact with pet bearded dragons. The high proportion of infants involved in this outbreak highlights the need to educate owners about the risk of RAS in children and the potential for household contamination by pet reptiles or their habitats. Strategies should be developed to improve breeding practices, biosecurity and monitoring protocols to reduce Salmonella in the pet reptile trade. [ABSTRACT FROM AUTHOR]

Published
2020
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14. Multistate Outbreak ofSalmonella entericaSerotype Enteritidis Infection Associated with Pet Guinea Pigs

Author

Bartholomew, Michael L., primary, Heffernan, Richard T., additional, Wright, Jennifer G., additional, Klos, Rachel F., additional, Monson, Timothy, additional, Khan, Sofiya, additional, Trees, Eija, additional, Sabol, Ashley, additional, Willems, Robert A., additional, Flynn, Raymond, additional, Deasy, Marshall P., additional, Jones, Benjamen, additional, and Davis, Jeffrey P., additional

Published
2014
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15. Escherichia coli O157:H7 Outbreak Associated with Seasonal Consumption of Raw Ground Beef — Wisconsin, December 2012–January 2013

Author

Quest, Carol, Klos, Rachel, Davis, Jeffrey P., and Canon, Abbey J.

Subjects
Adult, Aged, 80 and over, Male, Meat, Adolescent, Infant, Middle Aged, Escherichia coli O157, Disease Outbreaks, Young Adult, Wisconsin, Child, Preschool, Food Microbiology, Humans, Female, Seasons, Child, Notes from the Field, Escherichia coli Infections, Aged
Abstract

On January 8, 2013, the Wisconsin State Laboratory of Hygiene notified the Wisconsin Division of Public Health (WDPH) of two patients with Escherichia coli O157:H7 clinical isolates that had indistinguishable, but commonly identified, pulsed-field gel electrophoresis (PFGE) patterns. The two patients were interviewed by local health departments within 1 day of the initial report. They revealed that they had eaten raw ground beef purchased from the same meat market and served as "tiger meat" or "cannibal sandwiches." In this dish, the raw ground beef typically is served on rye bread or crackers with onions and is a traditional winter holiday specialty in certain regions of the upper Midwest. Five agencies (the Watertown Department of Health; WDPH; Wisconsin Department of Agriculture, Trade, and Consumer Protection; U.S. Department of Agriculture's Food Safety and Inspection Service; and CDC) investigated to determine the magnitude of the outbreak, prevent additional infections, and better understand raw ground beef consumption.

Published
2013

20. Multistate Outbreak of Salmonella enterica Serotype Enteritidis Infection Associated with Pet Guinea Pigs.

Author

Bartholomew, Michael L., Heffernan, Richard T., Wright, Jennifer G., Klos, Rachel F., Monson, Timothy, Khan, Sofiya, Trees, Eija, Sabol, Ashley, Willems, Robert A., Flynn, Raymond, Deasy, Marshall P., Jones, Benjamen, and Davis, Jeffrey P.

Subjects
SALMONELLA food poisoning, SALMONELLA infections in animals, SALMONELLA enteritidis, GUINEA pigs, FOODBORNE diseases
Abstract

Salmonella causes about one million illnesses annually in the United States. Although most infections result from foodborne exposures, animal contact is an important mode of transmission. We investigated a case of Salmonella enterica serotype Enteritidis (SE) sternal osteomyelitis in a previously healthy child who cared for two recently deceased guinea pigs (GPs). A case was defined as SE pulsed-field gel electrophoresis (PFGE) XbaI pattern JEGX01.0021, BlnI pattern JEGA26.0002 (outbreak strain) infection occurring during 2010 in a patient who reported GP exposure. To locate outbreak strain isolates, PulseNet and the US Department of Agriculture National Veterinary Service Laboratories (NVSL) databases were queried. Outbreak strain isolates underwent multilocus variable-number tandem repeat analysis (MLVA). Traceback and environmental investigations were conducted at homes, stores, and breeder or broker facilities. We detected 10 cases among residents of eight states and four NVSL GP outbreak strain isolates. One patient was hospitalized; none died. The median patient age was 9.5 (range, 1-61) years. Among 10 patients, two purchased GPs at independent stores, and three purchased GPs at different national retail chain (chain A) store locations; three were chain A employees and two reported GP exposures of unknown characterization. MLVA revealed four related patterns. Tracebacks identified four distributors and 92 sources supplying GPs to chain A, including one breeder potentially supplying GPs to all case-associated chain A stores. All environmental samples were Salmonella culture-negative. A definitive SE-contaminated environmental source was not identified. Because GPs can harbor Salmonella, consumers and pet industry personnel should be educated regarding risks. [ABSTRACT FROM AUTHOR]

Published
2014
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21. Multi-drug Resistant Salmonella Hadar Infections Associated with Turkey Burger Consumption.

Author

Green, Alice L., Klos, Rachel, Kirkpatrick, Jaime, Douris, Aphrodite, Cosgrove, Shaun, Miller, Ben, and Seys, Scott A.

Subjects
SALMONELLA infections in animals, MULTIDRUG resistance in bacteria, TURKEYS, PULSED-field gel electrophoresis, MICROBIAL sensitivity tests, CO-trimoxazole, DISEASES
Abstract

In mid-January 2011, the Minnesota Department of Agriculture's (MDA) retail food sampling program detected Salmonella Hadar in a turkey product produced by a corporation with nationwide distribution. Enhanced surveillance led the Wisconsin Department of Health Services (WDHS) to notify the United States Department of Agriculture Food Safety and Inspection Service (FSIS) of three clinical cases of Salmonella Hadar infection from January. The case-patient isolates were indistinguishable by Pulsed-Field Gel Electrophoresis (PFGE) from the MDA sample. All samples had resistance to five antimicrobials on the Wisconsin State Laboratory of Hygiene (WSLH) clinical test panel. The WSLH determined that Salmonella isolated from intact turkey product from a case-patient's home was indistinguishable from the outbreak strain by PFGE and antimicrobial susceptibility testing. The Food Safety Inspection Service tworked with additional states with illnesses in the cluster to determine exposures. This report describes the investigation that resulted in the first FSIS raw poultry recall due to contamination with multidrug resistant Salmonella in the United States. [ABSTRACT FROM AUTHOR]

Published
2014

22. An Outbreak of Foodborne Illness Among Attendees of a Wedding Reception in Wisconsin Likely Caused by Arcobacter butzleri

Author

Lappi, Victoria, Archer, John R., Cebelinski, Elizabeth, Leano, Fe, Besser, John M., Klos, Rachel F., Medus, Carlota, Smith, Kirk E., Fitzgerald, Collette, and Davis, Jeffrey P.

Abstract

AbstractBackground:Arcobacterspecies, primarily Arcobacter butzleri, are widely distributed among animals, infrequently isolated from humans, and previously not associated with outbreaks of foodborne illness. We report results of an investigation of a foodborne outbreak that occurred among attendees of a wedding reception in Wisconsin, United States, and was likely caused by A. butzleri.Methods:We conducted a case–control study among reception attendees and a laboratory investigation to determine the extent, source, and cause of the outbreak. A clinical case was defined as diarrhea in an attendee with illness onset ≤7 days following the wedding reception.Results:The case–control study included 47 of 51 case patients and 43 non-ill attendees. Results demonstrated that consuming broasted chicken was the only factor significantly associated with illness (odds ratio 10.51; 95% confidence interval 1.28, 476.4). Five patients provided stool specimens. Comprehensive culture and polymerase chain reaction (PCR) testing did not detect common bacterial or viral pathogens. Subsequent testing with PCRs targeting 16S/23S rDNA of the three most clinically relevant Arcobacterspp. and the rpoB/Cgene of A. butzleriprovided products confirmed as A. butzleri(four patients) and A. cryaerophilus(one patient) by sequence analysis.Conclusions:The results of this investigation suggest that A. butzlerishould be considered an agent that can cause outbreaks of foodborne illness. Rigorous investigation of outbreaks of undetermined etiology is valuable for incrementally increasing our understanding of emerging agents causing foodborne illnesses.

Published
2013
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23. Use of Traceback Methods To Confirm the Source of a Multistate Escherichia coliO157:H7 Outbreak Due to In-Shell Hazelnuts

Author

Miller, Benjamin D., Rigdon, Carrie E., Ball, Jill, Rounds, Joshua M., Klos, Rachel F., Brennan, Brenda M., Arends, Katherine D., Kennelly, Patrick, Hedberg, Craig, and Smith, Kirk E.

Abstract

Traceback methods by state regulatory agencies were used to complement traditional epidemiological cluster investigation methods and confirmed hazelnuts (also referred to as filberts) as the vehicle in a multistate outbreak of Escherichia coliO157:H7 infections. Bulk in-shell hazelnut and mixed-nut purchase locations were identified during the initial epidemiological interviews. Based on purchase dates and case onset dates, regulators in Minnesota, Michigan, and Wisconsin traced product back through the supply chain. Six (86%) retail locations received the suspect hazelnut or mixed-nut shipments from a Minnesota distributor, with one retailer (14%) receiving products from a Wisconsin distributor. Both distributors received 100% of their bulk in-shell hazelnuts and mixed nuts from a distributor in California. The California distributor received 99% of their hazelnuts from a packing company in Oregon. The California distributor received the hazelnuts in 50-lb (22.7-kg) bags and either resold them without opening the bags or used the in-shell hazelnuts in the manufacture of their in-shell mixed nuts. Records at the packing company in Oregon were incomplete or lacked sufficient detail needed to identify a suspect farm or group of suspect farms. Laboratory samples collected from human cases and subsequently recalled product matched the outbreak pulsed-field gel electrophoresis subtype of E. coliO157:H7. Hazelnut harvesting practices create a plausible route of contamination from fecal matter from domestic ruminants or wild deer. This outbreak investigation demonstrates the use of product traceback data to rapidly test an epidemiological hypothesis.

Published
2012
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24. Outbreak of Multidrug-Resistant SalmonellaHeidelberg Infections Linked to Dairy Calf Exposure, United States, 2015–2018

Author

Nichols, Megin, Gollarza, Lauren, Sockett, Donald, Aulik, Nicole, Patton, Elisabeth, Francois Watkins, Louise K., Gambino-Shirley, Kelly J., Folster, Jason P., Chen, Jessica C., Tagg, Kaitlin A., Stapleton, Gregory Sean, Trees, Eija, Ellison, Zachary, Lombard, Jason, Morningstar-Shaw, Brenda, Schlater, Linda, Elbadawi, Lina, and Klos, Rachel

Abstract

In August 2016, the Wisconsin Department of Health Services notified the U.S. Centers for Disease Control and Prevention of multidrug-resistant (MDR) Salmonella entericaserovar Heidelberg infections in people who reported contact with dairy calves. Federal and state partners investigated this to identify the source and scope of the outbreak and to prevent further illnesses. Cases were defined as human SalmonellaHeidelberg infection caused by a strain that had one of seven pulsed-field gel electrophoresis (PFGE) patterns or was related by whole genome sequencing (WGS), with illness onset from January 1, 2015, through July 2, 2018. Patient exposure and calf purchase information was collected and analyzed; calves were traced back from the point of purchase. Isolates obtained from animal and environmental samples collected on-farm were supplied by veterinary diagnostic laboratories and compared with patient isolates using PFGE and WGS. Antimicrobial susceptibility testing by standardized broth microdilution was performed. Sixty-eight patients from 17 states were identified. Forty (63%) of 64 patients noted cattle contact before illness. Thirteen (33%) of 40 patients with exposure to calves reported that calves were sick or had died. Seven individuals purchased calves from a single Wisconsin livestock market. One hundred forty cattle from 14 states were infected with the outbreak strain. WGS indicated that human, cattle, and environmental isolates from the livestock market were genetically closely related. Most isolates (88%) had resistance or reduced susceptibility to antibiotics of ≥5 antibiotic classes. This resistance profile included first-line antibiotic treatments for patients with severe salmonellosis, including ampicillin, ceftriaxone, and ciprofloxacin. In this outbreak, MDR SalmonellaHeidelberg likely spread from sick calves to humans, emphasizing the importance of illness surveillance in animal populations to prevent future spillover of this zoonotic disease.

Published
2022
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26. Notes from the Field.

Author

Quest, Carol, Klos, Rachel, Davis, Jeffrey P., and Canon, Abbey J.

Subjects
*ESCHERICHIA coli O157:H7, *EPIDEMICS, *BEEF contamination, *ESCHERICHIA coli disease prevention, *MEAT contamination
Abstract

The article discusses the outbreak of Escherichia coli O157:H7 associated with seasonal consumption of raw ground beef in Wisconsin from December 2012 to January 2013. The Wisconsin State Laboratory of Hygiene reported two patients with Escherichia coli O157:H7 after they had eaten raw ground beef purchased from the same meat market. Retailers are advised to discourage their consumers from eating raw ground beef in order to prevent the disease.

Published
2013

27. Epidemiologic and Clinical Features of Children and Adolescents Aged <18 Years with Monkeypox - United States, May 17-September 24, 2022.

Author

Hennessee I, Shelus V, McArdle CE, Wolf M, Schatzman S, Carpenter A, Minhaj FS, Petras JK, Cash-Goldwasser S, Maloney M, Sosa L, Jones SA, Mangla AT, Harold RE, Beverley J, Saunders KE, Adams JN, Stanek DR, Feldpausch A, Pavlick J, Cahill M, O'Dell V, Kim M, Alarcón J, Finn LE, Goss M, Duwell M, Crum DA, Williams TW, Hansen K, Heddy M, Mallory K, McDermott D, Cuadera MKQ, Adler E, Lee EH, Shinall A, Thomas C, Ricketts EK, Koonce T, Rynk DB, Cogswell K, McLafferty M, Perella D, Stockdale C, Dell B, Roskosky M, White SL, Davis KR, Milleron RS, Mackey S, Barringer LA, Bruce H, Barrett D, D'Angeli M, Kocharian A, Klos R, Dawson P, Ellington SR, Mayer O, Godfred-Cato S, Labuda SM, McCormick DW, McCollum AM, Rao AK, Salzer JS, Kimball A, and Gold JAW

Subjects
Child, Animals, Adolescent, Humans, United States epidemiology, Zoonoses epidemiology, Disease Outbreaks, Mpox, Monkeypox epidemiology
Abstract

Data on monkeypox in children and adolescents aged <18 years are limited (1,2). During May 17–September 24, 2022, a total of 25,038 monkeypox cases were reported in the United States, † primarily among adult gay, bisexual, and other men who have sex with men (3). During this period, CDC and U.S. jurisdictional health departments identified Monkeypox virus (MPXV) infections in 83 persons aged <18 years, accounting for 0.3% of reported cases. Among 28 children aged 0–12 years with monkeypox, 64% were boys, and most had direct skin-to-skin contact with an adult with monkeypox who was caring for the child in a household setting. Among 55 adolescents aged 13–17 years, most were male (89%), and male-to-male sexual contact was the most common presumed exposure route (66%). Most children and adolescents with monkeypox were non-Hispanic Black or African American (Black) (47%) or Hispanic or Latino (Hispanic) (35%). Most (89%) were not hospitalized, none received intensive care unit (ICU)–level care, and none died. Monkeypox in children and adolescents remains rare in the United States. Ensuring equitable access to monkeypox vaccination, testing, and treatment is a critical public health priority. Vaccination for adolescents with risk factors and provision of prevention information for persons with monkeypox caring for children might prevent additional infections., Competing Interests: All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. No potential conflicts of interest were disclosed.

Published
2022
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