Search

Your search keyword '"Klinke, Peter"' showing total 25 results
Start Over Author "Klinke, Peter"
25 results on '"Klinke, Peter"'

21. A comparison of the radial and the femoral approach in vein graft PCI. A retrospective study

Author

Ziakas, Antonios, Klinke, Peter, Mildenberger, Richard, Fretz, Eric, Williams, Malcolm, Della Siega, Antony, Kinloch, David, and Hilton, David

Abstract

BACKGROUND: Transradial PCI is a safe and effective method of percutaneous revascularization. However, there is limited data on the efficacy of the transradial approach for saphenous vein graft (SVG) PCI. METHODS: We studied 334 patients who underwent SVG PCI between January 2000 and December 2003, and compared the radial (132 patients) and the femoral (202 patients) approach. RESULTS: Mean EF (55.6±18.6% radial versus 58.1±16.8% femoral), lesion location (proximal, mid, distal: 22.6/50.6/26.7% versus 22.6/44.5/32.9% respectively) and lesion type (B1/B2/C: 3.4/4.1/92.5% versus 0.4/3.1/96.5%) were similar in both groups (P>0.05). Five patients had a failed radial attempt (3.8%) and were switched to the femoral approach. Mean fluoroscopy time (20.4±12.2 versus 18.4±10.2min), procedural time (60.0±27.2 versus 61.6±24.9min) and the use of contrast (223±91 versus 234±91ml) IIB/IIIA inhibitors (27.2 versus 33.2%), and stenting (81.5 versus 81.3%) were similar in both groups, whereas 5 or 6 French sheaths were used more often in the radial group (83.4 versus 64.9%, P<0.01). Angiographic success (93.9 versus 92.9%), in hospital MACE (radial:5 MI (3.8%) versus femoral: 1 death (0.5%) and 7 MI (3.5%) and major vascular complications (0.7 versus 0.5%) were also similar. CONCLUSIONS: The radial approach in SVG PCI is as fast and successful as the femoral.

Published
2005
Full Text
View/download PDF

25. Magnesium sulphate during transradial cardiac catheterization: a new use for an old drug?

Author

Byrne J, Spence M, Haegeli L, Fretz E, Della Siega A, Williams M, Kinloch D, Mildenberger R, Klinke P, and Hilton D

Subjects
Adult, Aged, Aged, 80 and over, Analgesics administration & dosage, Coronary Angiography drug effects, Double-Blind Method, Female, Hemodynamics drug effects, Humans, Magnesium Sulfate administration & dosage, Male, Middle Aged, Pain Measurement, Prospective Studies, Vasodilator Agents therapeutic use, Verapamil therapeutic use, Analgesics therapeutic use, Cardiac Catheterization adverse effects, Magnesium Sulfate therapeutic use, Pain drug therapy, Radial Artery drug effects, Spasm drug therapy
Abstract

Objective: To assess the effect of intra-arterial magnesium on the radial artery during transradial cardiac catheterization., Background: Transradial coronary angiography has become popular in the last decade and offers several advantages over transfemoral angiography. Radial artery spasm is a major limitation of this approach, and a vasodilatory cocktail is usually given. The aim of this study was to examine the effect of magnesium sulphate on the radial artery during cardiac catheterization., Methods: This was a prospective, double-blind, randomized trial of 86 patients undergoing radial catheterization. Patients were randomized to receive magnesium sulphate (150 mg) or verapamil (1 mg) into the radial sheath. Radial dimensions were assessed using Doppler ultrasound. The primary endpoint of the study was a change in radial artery diameter following administration. Secondary endpoints included operator-defined radial artery spasm and patient pain., Results: Following administration of the study drug, there was an increase in radial artery diameter in both groups (p < 0.01), although the increase seen was greater in the group receiving magnesium (magnesium 0.36 +/- 0.03 mm; verapamil 0.27 +/- 0.03 mm; p < 0.05). Administration of verapamil resulted in a fall in mean arterial pressure (MAP) (change in MAP -6.6 +/- 1.4 mmHg; p < 0.01), whereas magnesium did not have a hemodynamic effect. Severe arm pain (pain score > 5) was observed in 14 (30%) patients receiving verapamil and 9 (27%) receiving magnesium (p = NS)., Conclusion: This study demonstrates that magnesium is a more effective vasodilator when compared to verapamil, with a reduced hemodynamic effect, and is equally effective at preventing radial artery spasm. As such, the use of this agent offers distinct advantages over verapamil during radial catheterization.

Published
2008

Catalog

Books, media, physical & digital resources
See catalog results