Search

Additional file 1. Supplementary Methods.

Additional file 2. Fig. S1: Flow charts of inclusion/exclusion in cohort 1 (training) according to the REMARK guidelines. Fig. S2: Flow charts of inclusion/exclusion for cohorts 2-4. Fig. S3: Clustering of abundant circRNAs in cohort 1. Fig. S4: Association of abundant circRNAs to metastatic disease. Fig. S5: Association of abundant circRNAs to key clinicopathological parameters. Fig. S6: circKDM1A holds prognostic potential in prostate cancer patients. Fig. S7: circRNA candidates show both correlations and substantial differences between levels in EV-enriched plasma and in prostate tissue samples.