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10 results on '"Kleinwächter T"'

3. Beam driven plasma wakefield acceleration at FLASHForward

Author

Schaper, L., Behrens, C., Kononenko, O., Libov, V., Martinez de la Ossa, A., Mehrling, T., Palmer, C., Schlarb, H., Schmidt, B., Schwinkendorf, J.-P., Streeter, M., Tauscher, G., Dale, J., Wacker, V., Wunderlich, S., Zemella, J., Osterhoff, J., Elsen, E., Felber, M., Foster, B., Goldberg, L., Hidding, B., Kleinwächter, T., and Knetsch, A.

Published
2015

4. FLASHForward - Future-oriented wakefield-accelerator research and development at FLASH

Author

Libov, V., Aschikhin, A., Hidding, B., Kleinwächter, T., Knetsch, A., Kononenko, O., Ludwig, K., Martinez de la Ossa, A., Mehrling, T., Olgun, H., Palmer, C., Schaper, L., Behrens, C., Schlarb, H., Schmidt, B., Schwinkendorf, J. P., Streeter, M., Wunderlich, S., Zemella, J., Osterhoff, J., Dale, J., Elsen, E., Entrena Utrilla, C., Felber, M., Foster, B., Goldberg, L., and Grebenyuk, J.

Published
2014

6. High Quality Electron Beams from Beam-Driven Plasma Wakefield Accelerators

Author

Osterhoff, J., Aschikhin, A., Martinez de la Ossa, A., Mehrling, T., Olgun, H. T., Palmer, C. A. J., Schaper, L., Schmidt, B., Schwinkendorf, J.-P., Streeter, M., Wunderlich, S., Zemella, J., Behrens, C., Dale, J., Entrena, C., Goldberg, L., Grebenyuk, J., Kleinwächter, T., Kononenko, O., and Libov, V.

Abstract

The field of particle acceleration in plasma wakes has seen remarkable progress in recent years. Accelerating gradients of more than 10 GV/m can now be readily achieved using either ultra-short intense laser pulses or particle beams as wake drivers. The demonstration of the first GeV electron beams and a general trend towards improved reproducibility, beam quality and control over the involved plasma processes has led to plasma-acceleration techniques drawing considerable interest in the traditional accelerator community. As a consequence, DESY, Germany's leading accelerator centre, has established the FLASHForward research programme for novel acceleration techniques exploiting the synergetic combination of conventional and new technology at the FLASH accelerator. FLASHForward aims at producing high-quality electron beams from a beam-driven plasma-wakefield concept utilizing controlled electron-injection techniques with the grand goal to apply these beams for the realization of a plasma-boosted free-electron laser.

Published
2013

10. QTL for the heritable inverted teat defect in pigs.

Author

Jonas E, Schreinemachers HJ, Kleinwächter T, Un C, Oltmanns I, Tetzlaff S, Jennen D, Tesfaye D, Ponsuksili S, Murani E, Juengst H, Tholen E, Schellander K, and Wimmers K

Subjects
Animals, Chromosomes, Mammalian genetics, Crosses, Genetic, Female, Male, Mammary Glands, Animal abnormalities, Quantitative Trait Loci genetics, Quantitative Trait, Heritable, Sus scrofa genetics
Abstract

The mothering ability of a sow largely depends on the shape and function of the mammary gland. The aim of this study was to identify QTL for the heritable inverted teat defect, a condition characterized by disturbed development of functional teats. A QTL analysis was conducted in a porcine experimental population based on Duroc and Berlin Miniature pigs (DUMI). The significant QTL were confirmed by linkage analysis in commercial pigs according to the affected sib pair design and refined by family-based association test (FBAT). Nonparametric linkage (NPL) analysis revealed five significant and seven suggestive QTL for the inverted teat defect in the porcine experimental population. In commercial dam lines five significant NPL values were detected. QTL regions in overlapping marker intervals or close proximity in both populations were found on SSC3, SSC4, SSC6, and SSC11. SSC6 revealed QTL in both populations at different positions, indicating the segregation of at least two QTL. The results confirm the previously proposed polygenic inheritance of the inverted teat defect and, for the first time, point to genomic regions harboring relevant genes. The investigation revealed variation of the importance of QTL in the various populations due to either differences in allele frequencies and statistical power or differences in the genetic background that modulates the impact of the liability loci on the expression of the disease. The QTL study enabled us to name a number of plausible positional candidate genes. The correspondence of QTL regions for the inverted teat defect and previously mapped QTL for teat number are in line with the etiologic relationship of these traits.

Published
2008
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