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231 results on '"Klarenbeek, Sjoerd"'

1. CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer

Author

Houthuijzen, Julia M., de Bruijn, Roebi, van der Burg, Eline, Drenth, Anne Paulien, Wientjens, Ellen, Filipovic, Tamara, Bullock, Esme, Brambillasca, Chiara S., Pulver, Emilia M., Nieuwland, Marja, de Rink, Iris, van Diepen, Frank, Klarenbeek, Sjoerd, Kerkhoven, Ron, Brunton, Valerie G., Scheele, Colinda L.G.J., Boelens, Mirjam C., and Jonkers, Jos

Published
2023
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4. Truncated FGFR2 is a clinically actionable oncogene in multiple cancers

Author

Zingg, Daniel, Bhin, Jinhyuk, Yemelyanenko, Julia, Kas, Sjors M., Rolfs, Frank, Lutz, Catrin, Lee, Jessica K., Klarenbeek, Sjoerd, Silverman, Ian M., Annunziato, Stefano, Chan, Chang S., Piersma, Sander R., Eijkman, Timo, Badoux, Madelon, Gogola, Ewa, Siteur, Bjørn, Sprengers, Justin, de Klein, Bim, de Goeij-de Haas, Richard R., Riedlinger, Gregory M., Ke, Hua, Madison, Russell, Drenth, Anne Paulien, van der Burg, Eline, Schut, Eva, Henneman, Linda, van Miltenburg, Martine H., Proost, Natalie, Zhen, Huiling, Wientjens, Ellen, de Bruijn, Roebi, de Ruiter, Julian R., Boon, Ute, de Korte-Grimmerink, Renske, van Gerwen, Bastiaan, Féliz, Luis, Abou-Alfa, Ghassan K., Ross, Jeffrey S., van de Ven, Marieke, Rottenberg, Sven, Cuppen, Edwin, Chessex, Anne Vaslin, Ali, Siraj M., Burn, Timothy C., Jimenez, Connie R., Ganesan, Shridar, Wessels, Lodewyk F. A., and Jonkers, Jos

Published
2022
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6. Publisher Correction: Truncated FGFR2 is a clinically actionable oncogene in multiple cancers

Author

Zingg, Daniel, Bhin, Jinhyuk, Yemelyanenko, Julia, Kas, Sjors M., Rolfs, Frank, Lutz, Catrin, Lee, Jessica K., Klarenbeek, Sjoerd, Silverman, Ian M., Annunziato, Stefano, Chan, Chang S., Piersma, Sander R., Eijkman, Timo, Badoux, Madelon, Gogola, Ewa, Siteur, Bjørn, Sprengers, Justin, de Klein, Bim, de Goeij-de Haas, Richard R., Riedlinger, Gregory M., Ke, Hua, Madison, Russell, Drenth, Anne Paulien, van der Burg, Eline, Schut, Eva, Henneman, Linda, van Miltenburg, Martine H., Proost, Natalie, Zhen, Huiling, Wientjens, Ellen, de Bruijn, Roebi, de Ruiter, Julian R., Boon, Ute, de Korte-Grimmerink, Renske, van Gerwen, Bastiaan, Féliz, Luis, Abou-Alfa, Ghassan K., Ross, Jeffrey S., van de Ven, Marieke, Rottenberg, Sven, Cuppen, Edwin, Chessex, Anne Vaslin, Ali, Siraj M., Burn, Timothy C., Jimenez, Connie R., Ganesan, Shridar, Wessels, Lodewyk F. A., and Jonkers, Jos

Published
2022
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8. MYC is a clinically significant driver of mTOR inhibitor resistance in breast cancer

Author

Bhin, Jinhyuk, primary, Yemelyanenko, Julia, additional, Chao, Xue, additional, Klarenbeek, Sjoerd, additional, Opdam, Mark, additional, Malka, Yuval, additional, Hoekman, Liesbeth, additional, Kruger, Dinja, additional, Bleijerveld, Onno, additional, Brambillasca, Chiara S., additional, Sprengers, Justin, additional, Siteur, Bjørn, additional, Annunziato, Stefano, additional, van Haren, Matthijs J., additional, Martin, Nathaniel I., additional, van de Ven, Marieke, additional, Peters, Dennis, additional, Agami, Reuven, additional, Linn, Sabine C., additional, Boven, Epie, additional, Altelaar, Maarten, additional, Jonkers, Jos, additional, Zingg, Daniel, additional, and Wessels, Lodewyk F.A., additional

Published
2023
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10. Neoadjuvant immune checkpoint blockade triggers persistent and systemic Treg activation which blunts therapeutic efficacy against metastatic spread of breast tumors

Author

Blomberg, Olga S., primary, Kos, Kevin, additional, Spagnuolo, Lorenzo, additional, Isaeva, Olga I., additional, Garner, Hannah, additional, Wellenstein, Max D., additional, Bakker, Noor, additional, Duits, Danique E.M., additional, Kersten, Kelly, additional, Klarenbeek, Sjoerd, additional, Hau, Cheei-Sing, additional, Kaldenbach, Daphne, additional, Raeven, Elisabeth A.M., additional, Vrijland, Kim, additional, Kok, Marleen, additional, and de Visser, Karin E., additional

Published
2023
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11. Abstract 3488: Truncated FGFR2 - a clinically actionable oncogene in multiple cancers

Author

Zingg, Daniel Kaspar, primary, Bhin, Jinhyuk, additional, Yemelyanenko, Julia, additional, Kas, Sjors M., additional, Lutz, Catrin, additional, Lin, Chi-Chuan, additional, Klarenbeek, Sjoerd, additional, Lee, Jessica K., additional, Silverman, Ian M., additional, Annunziato, Stefano, additional, Ven, Marieke van de, additional, Ali, Siraj M., additional, Burn, Timothy C., additional, Ganesan, Shridar, additional, Wessels, Lodewyk F., additional, and Jonkers, Jos, additional

Published
2023
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12. Supplementary data from Transcriptomics and Transposon Mutagenesis Identify Multiple Mechanisms of Resistance to the FGFR Inhibitor AZD4547

Author

Kas, Sjors M., primary, de Ruiter, Julian R., primary, Schipper, Koen, primary, Schut, Eva, primary, Bombardelli, Lorenzo, primary, Wientjens, Ellen, primary, Drenth, Anne Paulien, primary, de Korte-Grimmerink, Renske, primary, Mahakena, Sunny, primary, Phillips, Christopher, primary, Smith, Paul D., primary, Klarenbeek, Sjoerd, primary, van de Wetering, Koen, primary, Berns, Anton, primary, Wessels, Lodewyk F.A., primary, and Jonkers, Jos, primary

Published
2023
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15. Supplementary Figures S1-5 from Transcriptomics and Transposon Mutagenesis Identify Multiple Mechanisms of Resistance to the FGFR Inhibitor AZD4547

Author

Kas, Sjors M., primary, de Ruiter, Julian R., primary, Schipper, Koen, primary, Schut, Eva, primary, Bombardelli, Lorenzo, primary, Wientjens, Ellen, primary, Drenth, Anne Paulien, primary, de Korte-Grimmerink, Renske, primary, Mahakena, Sunny, primary, Phillips, Christopher, primary, Smith, Paul D., primary, Klarenbeek, Sjoerd, primary, van de Wetering, Koen, primary, Berns, Anton, primary, Wessels, Lodewyk F.A., primary, and Jonkers, Jos, primary

Published
2023
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16. Data from A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair

Author

Pulver, Emilia M., primary, Mukherjee, Chirantani, primary, van de Kamp, Gerarda, primary, Roobol, Stefan J., primary, Rother, Magdalena B., primary, van der Gulden, Hanneke, primary, de Bruijn, Roebi, primary, Lattanzio, Maria Valeria, primary, van der Burg, Eline, primary, Drenth, Anne Paulien, primary, Verkaik, Nicole S., primary, Hahn, Kerstin, primary, Klarenbeek, Sjoerd, primary, de Korte-Grimmerink, Renske, primary, van de Ven, Marieke, primary, Pritchard, Colin E.J., primary, Huijbers, Ivo J., primary, Xia, Bing, primary, van Gent, Dik C., primary, Essers, Jeroen, primary, van Attikum, Haico, primary, Ray Chaudhuri, Arnab, primary, Bouwman, Peter, primary, and Jonkers, Jos, primary

Published
2023
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19. Supplementary Data from A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair

Author

Pulver, Emilia M., primary, Mukherjee, Chirantani, primary, van de Kamp, Gerarda, primary, Roobol, Stefan J., primary, Rother, Magdalena B., primary, van der Gulden, Hanneke, primary, de Bruijn, Roebi, primary, Lattanzio, Maria Valeria, primary, van der Burg, Eline, primary, Drenth, Anne Paulien, primary, Verkaik, Nicole S., primary, Hahn, Kerstin, primary, Klarenbeek, Sjoerd, primary, de Korte-Grimmerink, Renske, primary, van de Ven, Marieke, primary, Pritchard, Colin E.J., primary, Huijbers, Ivo J., primary, Xia, Bing, primary, van Gent, Dik C., primary, Essers, Jeroen, primary, van Attikum, Haico, primary, Ray Chaudhuri, Arnab, primary, Bouwman, Peter, primary, and Jonkers, Jos, primary

Published
2023
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20. Data from Transcriptomics and Transposon Mutagenesis Identify Multiple Mechanisms of Resistance to the FGFR Inhibitor AZD4547

Author

Kas, Sjors M., primary, de Ruiter, Julian R., primary, Schipper, Koen, primary, Schut, Eva, primary, Bombardelli, Lorenzo, primary, Wientjens, Ellen, primary, Drenth, Anne Paulien, primary, de Korte-Grimmerink, Renske, primary, Mahakena, Sunny, primary, Phillips, Christopher, primary, Smith, Paul D., primary, Klarenbeek, Sjoerd, primary, van de Wetering, Koen, primary, Berns, Anton, primary, Wessels, Lodewyk F.A., primary, and Jonkers, Jos, primary

Published
2023
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21. Supplementary Figure 2 from Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling

Author

Schackmann, Ron C.J., primary, Klarenbeek, Sjoerd, primary, Vlug, Eva J., primary, Stelloo, Suzan, primary, van Amersfoort, Miranda, primary, Tenhagen, Milou, primary, Braumuller, Tanya M., primary, Vermeulen, Jeroen F., primary, van der Groep, Petra, primary, Peeters, Ton, primary, van der Wall, Elsken, primary, van Diest, Paul J., primary, Jonkers, Jos, primary, and Derksen, Patrick W.B., primary

Published
2023
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24. Supplementary Figure 3 from Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling

Author

Schackmann, Ron C.J., primary, Klarenbeek, Sjoerd, primary, Vlug, Eva J., primary, Stelloo, Suzan, primary, van Amersfoort, Miranda, primary, Tenhagen, Milou, primary, Braumuller, Tanya M., primary, Vermeulen, Jeroen F., primary, van der Groep, Petra, primary, Peeters, Ton, primary, van der Wall, Elsken, primary, van Diest, Paul J., primary, Jonkers, Jos, primary, and Derksen, Patrick W.B., primary

Published
2023
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26. Supplementary Figure Legends from Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling

Author

Schackmann, Ron C.J., primary, Klarenbeek, Sjoerd, primary, Vlug, Eva J., primary, Stelloo, Suzan, primary, van Amersfoort, Miranda, primary, Tenhagen, Milou, primary, Braumuller, Tanya M., primary, Vermeulen, Jeroen F., primary, van der Groep, Petra, primary, Peeters, Ton, primary, van der Wall, Elsken, primary, van Diest, Paul J., primary, Jonkers, Jos, primary, and Derksen, Patrick W.B., primary

Published
2023
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29. Supplementary Figure 5 from Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling

Author

Schackmann, Ron C.J., primary, Klarenbeek, Sjoerd, primary, Vlug, Eva J., primary, Stelloo, Suzan, primary, van Amersfoort, Miranda, primary, Tenhagen, Milou, primary, Braumuller, Tanya M., primary, Vermeulen, Jeroen F., primary, van der Groep, Petra, primary, Peeters, Ton, primary, van der Wall, Elsken, primary, van Diest, Paul J., primary, Jonkers, Jos, primary, and Derksen, Patrick W.B., primary

Published
2023
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30. Supplementary Figure 6 from Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling

Author

Schackmann, Ron C.J., primary, Klarenbeek, Sjoerd, primary, Vlug, Eva J., primary, Stelloo, Suzan, primary, van Amersfoort, Miranda, primary, Tenhagen, Milou, primary, Braumuller, Tanya M., primary, Vermeulen, Jeroen F., primary, van der Groep, Petra, primary, Peeters, Ton, primary, van der Wall, Elsken, primary, van Diest, Paul J., primary, Jonkers, Jos, primary, and Derksen, Patrick W.B., primary

Published
2023
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31. Supplementary Figure 1 from Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling

Author

Schackmann, Ron C.J., primary, Klarenbeek, Sjoerd, primary, Vlug, Eva J., primary, Stelloo, Suzan, primary, van Amersfoort, Miranda, primary, Tenhagen, Milou, primary, Braumuller, Tanya M., primary, Vermeulen, Jeroen F., primary, van der Groep, Petra, primary, Peeters, Ton, primary, van der Wall, Elsken, primary, van Diest, Paul J., primary, Jonkers, Jos, primary, and Derksen, Patrick W.B., primary

Published
2023
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33. Supplementary Figure 4 from Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling

Author

Schackmann, Ron C.J., primary, Klarenbeek, Sjoerd, primary, Vlug, Eva J., primary, Stelloo, Suzan, primary, van Amersfoort, Miranda, primary, Tenhagen, Milou, primary, Braumuller, Tanya M., primary, Vermeulen, Jeroen F., primary, van der Groep, Petra, primary, Peeters, Ton, primary, van der Wall, Elsken, primary, van Diest, Paul J., primary, Jonkers, Jos, primary, and Derksen, Patrick W.B., primary

Published
2023
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34. Supplementary Table 3 from Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling

Author

Schackmann, Ron C.J., primary, Klarenbeek, Sjoerd, primary, Vlug, Eva J., primary, Stelloo, Suzan, primary, van Amersfoort, Miranda, primary, Tenhagen, Milou, primary, Braumuller, Tanya M., primary, Vermeulen, Jeroen F., primary, van der Groep, Petra, primary, Peeters, Ton, primary, van der Wall, Elsken, primary, van Diest, Paul J., primary, Jonkers, Jos, primary, and Derksen, Patrick W.B., primary

Published
2023
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35. Supplementary Table 4 from Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling

Author

Schackmann, Ron C.J., primary, Klarenbeek, Sjoerd, primary, Vlug, Eva J., primary, Stelloo, Suzan, primary, van Amersfoort, Miranda, primary, Tenhagen, Milou, primary, Braumuller, Tanya M., primary, Vermeulen, Jeroen F., primary, van der Groep, Petra, primary, Peeters, Ton, primary, van der Wall, Elsken, primary, van Diest, Paul J., primary, Jonkers, Jos, primary, and Derksen, Patrick W.B., primary

Published
2023
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36. Supplementary Table 1 from Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling

Author

Schackmann, Ron C.J., primary, Klarenbeek, Sjoerd, primary, Vlug, Eva J., primary, Stelloo, Suzan, primary, van Amersfoort, Miranda, primary, Tenhagen, Milou, primary, Braumuller, Tanya M., primary, Vermeulen, Jeroen F., primary, van der Groep, Petra, primary, Peeters, Ton, primary, van der Wall, Elsken, primary, van Diest, Paul J., primary, Jonkers, Jos, primary, and Derksen, Patrick W.B., primary

Published
2023
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37. Supplementary Table 2 from Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling

Author

Schackmann, Ron C.J., primary, Klarenbeek, Sjoerd, primary, Vlug, Eva J., primary, Stelloo, Suzan, primary, van Amersfoort, Miranda, primary, Tenhagen, Milou, primary, Braumuller, Tanya M., primary, Vermeulen, Jeroen F., primary, van der Groep, Petra, primary, Peeters, Ton, primary, van der Wall, Elsken, primary, van Diest, Paul J., primary, Jonkers, Jos, primary, and Derksen, Patrick W.B., primary

Published
2023
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39. Supplementary Materials and Methods from Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling

Author

Schackmann, Ron C.J., primary, Klarenbeek, Sjoerd, primary, Vlug, Eva J., primary, Stelloo, Suzan, primary, van Amersfoort, Miranda, primary, Tenhagen, Milou, primary, Braumuller, Tanya M., primary, Vermeulen, Jeroen F., primary, van der Groep, Petra, primary, Peeters, Ton, primary, van der Wall, Elsken, primary, van Diest, Paul J., primary, Jonkers, Jos, primary, and Derksen, Patrick W.B., primary

Published
2023
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41. MYC is a clinically significant driver of mTOR inhibitor resistance in breast cancer

Author

Bhin, Jinhyuk, Yemelyanenko, Julia, Chao, Xue, Klarenbeek, Sjoerd, Opdam, Mark, Malka, Yuval, Hoekman, Liesbeth, Kruger, Dinja, Bleijerveld, Onno, Brambillasca, Chiara S., Sprengers, Justin, Siteur, Bjørn, Annunziato, Stefano, van Haren, Matthijs J., Martin, Nathaniel I., van de Ven, Marieke, Peters, Dennis, Agami, Reuven, Linn, Sabine C., Boven, Epie, Altelaar, Maarten, Jonkers, Jos, Zingg, Daniel, Wessels, Lodewyk F.A., Bhin, Jinhyuk, Yemelyanenko, Julia, Chao, Xue, Klarenbeek, Sjoerd, Opdam, Mark, Malka, Yuval, Hoekman, Liesbeth, Kruger, Dinja, Bleijerveld, Onno, Brambillasca, Chiara S., Sprengers, Justin, Siteur, Bjørn, Annunziato, Stefano, van Haren, Matthijs J., Martin, Nathaniel I., van de Ven, Marieke, Peters, Dennis, Agami, Reuven, Linn, Sabine C., Boven, Epie, Altelaar, Maarten, Jonkers, Jos, Zingg, Daniel, and Wessels, Lodewyk F.A.

Abstract

Targeting the PI3K–AKT–mTOR pathway is a promising therapeutic strategy for breast cancer treatment. However, low response rates and development of resistance to PI3K–AKT–mTOR inhibitors remain major clinical challenges. Here, we show that MYC activation drives resistance to mTOR inhibitors (mTORi) in breast cancer. Multiomic profiling of mouse invasive lobular carcinoma (ILC) tumors revealed recurrent Myc amplifications in tumors that acquired resistance to the mTORi AZD8055. MYC activation was associated with biological processes linked to mTORi response and counteracted mTORi-induced translation inhibition by promoting translation of ribosomal proteins. In vitro and in vivo induction of MYC conferred mTORi resistance in mouse and human breast cancer models. Conversely, AZD8055-resistant ILC cells depended on MYC, as demonstrated by the synergistic effects of mTORi and MYCi combination treatment. Notably, MYC status was significantly associated with poor response to everolimus therapy in metastatic breast cancer patients. Thus, MYC is a clinically relevant driver of mTORi resistance that may stratify breast cancer patients for mTOR-targeted therapies.

Published
2023

42. MYC is a clinically significant driver of mTOR inhibitor resistance in breast cancer

Author

Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics, Chemical Biology and Drug Discovery, Bhin, Jinhyuk, Yemelyanenko, Julia, Chao, Xue, Klarenbeek, Sjoerd, Opdam, Mark, Malka, Yuval, Hoekman, Liesbeth, Kruger, Dinja, Bleijerveld, Onno, Brambillasca, Chiara S., Sprengers, Justin, Siteur, Bjørn, Annunziato, Stefano, van Haren, Matthijs J., Martin, Nathaniel I., van de Ven, Marieke, Peters, Dennis, Agami, Reuven, Linn, Sabine C., Boven, Epie, Altelaar, Maarten, Jonkers, Jos, Zingg, Daniel, Wessels, Lodewyk F.A., Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics, Chemical Biology and Drug Discovery, Bhin, Jinhyuk, Yemelyanenko, Julia, Chao, Xue, Klarenbeek, Sjoerd, Opdam, Mark, Malka, Yuval, Hoekman, Liesbeth, Kruger, Dinja, Bleijerveld, Onno, Brambillasca, Chiara S., Sprengers, Justin, Siteur, Bjørn, Annunziato, Stefano, van Haren, Matthijs J., Martin, Nathaniel I., van de Ven, Marieke, Peters, Dennis, Agami, Reuven, Linn, Sabine C., Boven, Epie, Altelaar, Maarten, Jonkers, Jos, Zingg, Daniel, and Wessels, Lodewyk F.A.

Published
2023

43. Natural deletion of mouse carboxylesterases Ces1c/d/e impacts drug metabolism and metabolic syndrome development

Author

Afd Pharmacoepi & Clinical Pharmacology, Afd Biomol.Mass Spect. and Proteomics, Pharmacoepidemiology and Clinical Pharmacology, Biomolecular Mass Spectrometry and Proteomics, Gan, Changpei, Wang, Jing, Wang, Yaogeng, Martínez-Chávez, Alejandra, Hillebrand, Michel, de Vries, Niels, Beukers, Joke, Lebre, Maria C., Wagenaar, Els, Rosing, Hilde, Klarenbeek, Sjoerd, Bleijerveld, Onno B., Song, Ji Ying, Altelaar, Maarten, Beijnen, Jos H., Schinkel, Alfred H., Afd Pharmacoepi & Clinical Pharmacology, Afd Biomol.Mass Spect. and Proteomics, Pharmacoepidemiology and Clinical Pharmacology, Biomolecular Mass Spectrometry and Proteomics, Gan, Changpei, Wang, Jing, Wang, Yaogeng, Martínez-Chávez, Alejandra, Hillebrand, Michel, de Vries, Niels, Beukers, Joke, Lebre, Maria C., Wagenaar, Els, Rosing, Hilde, Klarenbeek, Sjoerd, Bleijerveld, Onno B., Song, Ji Ying, Altelaar, Maarten, Beijnen, Jos H., and Schinkel, Alfred H.

Published
2023

45. Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L‐dose dependency in HDAC1‐deficient thymic lymphoma

Author

Vlaming, Hanneke, McLean, Chelsea M, Korthout, Tessy, Alemdehy, Mir Farshid, Hendriks, Sjoerd, Lancini, Cesare, Palit, Sander, Klarenbeek, Sjoerd, Kwesi‐Maliepaard, Eliza Mari, Molenaar, Thom M, Hoekman, Liesbeth, Schmidlin, Thierry T, Altelaar, AF Maarten, van Welsem, Tibor, Dannenberg, Jan‐Hermen, Jacobs, Heinz, and van Leeuwen, Fred

Published
2019
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47. Publisher Correction:Truncated FGFR2 is a clinically actionable oncogene in multiple cancers (Nature, (2022), 608, 7923, (609-617), 10.1038/s41586-022-05066-5)

Author

Zingg, Daniel, Bhin, Jinhyuk, Yemelyanenko, Julia, Kas, Sjors M., Rolfs, Frank, Lutz, Catrin, Lee, Jessica K., Klarenbeek, Sjoerd, Silverman, Ian M., Annunziato, Stefano, Chan, Chang S., Piersma, Sander R., Eijkman, Timo, Badoux, Madelon, Gogola, Ewa, Siteur, Bjørn, Sprengers, Justin, de Klein, Bim, de Goeij-de Haas, Richard R., Riedlinger, Gregory M., Ke, Hua, Madison, Russell, Drenth, Anne Paulien, van der Burg, Eline, Schut, Eva, Henneman, Linda, van Miltenburg, Martine H., Proost, Natalie, Zhen, Huiling, Wientjens, Ellen, de Bruijn, Roebi, de Ruiter, Julian R., Boon, Ute, de Korte-Grimmerink, Renske, van Gerwen, Bastiaan, Féliz, Luis, Abou-Alfa, Ghassan K., Ross, Jeffrey S., van de Ven, Marieke, Rottenberg, Sven, Cuppen, Edwin, Chessex, Anne Vaslin, Ali, Siraj M., Burn, Timothy C., Jimenez, Connie R., Ganesan, Shridar, Wessels, Lodewyk F. A., Jonkers, Jos, Medical oncology laboratory, CCA - Cancer biology and immunology, CCA - Imaging and biomarkers, and Amsterdam Neuroscience - Neurodegeneration

Abstract

This paper was originally published under a standard Springer Nature license (

Published
2022

48. Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism

Author

Gan, Changpei, primary, Wang, Jing, additional, Martínez-Chávez, Alejandra, additional, Hillebrand, Michel, additional, de Vries, Niels, additional, Beukers, Joke, additional, Wagenaar, Els, additional, Wang, Yaogeng, additional, Lebre, Maria C., additional, Rosing, Hilde, additional, Klarenbeek, Sjoerd, additional, Ali, Rahmen Bin, additional, Pritchard, Colin, additional, Huijbers, Ivo, additional, Beijnen, Jos H., additional, and Schinkel, Alfred H., additional

Published
2022
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49. CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer

Author

Houthuijzen, Julia M., primary, de Bruijn, Roebi, additional, van der Burg, Eline, additional, Drenth, Anne Paulien, additional, Wientjens, Ellen, additional, Filipovic, Tamara, additional, Bullock, Esme, additional, Brambillasca, Chiara S., additional, Nieuwland, Marja, additional, de Rink, Iris, additional, van Diepen, Frank, additional, Klarenbeek, Sjoerd, additional, Kerkhoven, Ron, additional, Brunton, Valerie G., additional, Scheele, Colinda L.G.J., additional, Boelens, Mirjam C., additional, and Jonkers, Jos, additional

Published
2022
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