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337 results on '"Kitagawa, Toshiro"'

4. Determination of lipid-rich plaques by artificial intelligence-enabled quantitative computed tomography using near-infrared spectroscopy as reference

Author

Omori, Hiroyuki, Matsuo, Hitoshi, Fujimoto, Shinichiro, Sobue, Yoshihiro, Nozaki, Yui, Nakazawa, Gaku, Takahashi, Kuniaki, Osawa, Kazuhiro, Okubo, Ryo, Kaneko, Umihiko, Sato, Hideyuki, Kajiya, Takashi, Miyoshi, Toru, Ichikawa, Keishi, Abe, Mitsunori, Kitagawa, Toshiro, Ikenaga, Hiroki, Saji, Mike, Iguchi, Nobuo, Ijichi, Takeshi, Mikamo, Hiroshi, Kurata, Akira, Moroi, Masao, Iijima, Raisuke, Malkasian, Shant, Crabtree, Tami, Min, James K., Earls, James P., and Nakanishi, Rine

Published
2023
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6. Rationale and design of the INVICTUS Registry: (Multicenter Registry of Invasive and Non-Invasive imaging modalities to compare Coronary Computed Tomography Angiography, Intravascular Ultrasound and Optical Coherence Tomography for the determination of Severity, Volume and Type of coronary atherosclerosiS)

Author

Nakanishi, Rine, Okubo, Ryo, Sobue, Yoshihiro, Kaneko, Umihiko, Sato, Hideyuki, Fujimoto, Shinichiro, Nozaki, Yui, Kajiya, Takashi, Miyoshi, Toru, Ichikawa, Keishi, Abe, Mitsunori, Kitagawa, Toshiro, Ikenaga, Hiroki, Osawa, Kazuhiro, Saji, Mike, Iguchi, Nobuo, Nakazawa, Gaku, Takahashi, Kuniaki, Ijich, Takeshi, Mikamo, Hiroshi, Kurata, Akira, Moroi, Masao, Iijima, Raisuke, Malkasian, Shant, Crabtree, Tami, Chamie, Daniel, Lansky, Alexandra J., Min, James K., Earls, James P., and Matsuo, Hitoshi

Published
2023
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11. Abstract 13674: Optimal Hounsfield Threshold for Lipid-Rich Plaque by Artificial Intelligence-Enabled Quantitative CT Using Near-Infrared Spectroscopy

Author

Omori, Hiroyuki, Matsuo, Hitoshi, Earls, James, Sobue, Yoshihiro, Fujimoto, Shinichiro, Nozaki, Yui, Nakazawa, Gaku, Takahashi, Kuniaki, Osawa, Kazuhiro, Okubo, Ryo, Kaneko, Umihiko, Sato, Hideyuki, Kajiya, Takashi, Miyoshi, Toru, Ichikawa, Keishi, Abe, Mitsunori, Kitagawa, Toshiro, Ikenaga, Hiroki, Saji, Mike, Iguchi, Nobuo, Ijichi, Takeshi, Mikamo, Hiroshi, Kurata, Akira, Moroi, Masao, iijima, raisuke, Crabtree, Tami, Min, James K, and Nakanishi, Rine

Published
2022
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12. Abstract 13665: Determination of Lipid-Rich Plaque by Artificial Intelligence-Enabled Quantitative Computed Tomography Using Near-Infrared Spectroscopy

Author

Omori, Hiroyuki, Matsuo, Hitoshi, Earls, James, Sobue, Yoshihiro, Fujimoto, Shinichiro, Nozaki, Yui, Nakazawa, Gaku, Takahashi, Kuniaki, Osawa, Kazuhiro, Okubo, Ryo, Kaneko, Umihiko, Sato, Hideyuki, Kajiya, Takashi, Miyoshi, Toru, Ichikawa, Keishi, Abe, Mitsunori, Kitagawa, Toshiro, Ikenaga, Hiroki, Saji, Mike, Iguchi, Nobuo, Ijichi, Takeshi, Mikamo, Hiroshi, Kurata, Akira, Moroi, Masao, iijima, raisuke, Crabtree, Tami, Min, James K, and Nakanishi, Rine

Published
2022
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17. Coronary plaque characteristics in computed tomography and 2-year outcomes: The PREDICT study

Author

Utsunomiya, Hiroto, Senoo, Atsuhiro, Matsunaga, Eriko, Takamura, Kazuhisa, Kinoshita, Ryoko, Hayashi, Yasuhiko, Himeno, Hideo, Kondo, Takeshi, Fujimoto, Shinichiro, Yamashina, Akira, Hirano, Masaharu, Ando, Kenji, Yamaji, Kyohei, Inoue, Noriko, Dote, Keigo, Kato, Masaya, Sasaki, Shota, Kawamura, Masaki, Oshima, Kiyotaka, Hirayama, Atsushi, Yoda, Shunichi, Yoshino, Hideaki, Ishiguro, Haruhisa, Doi, Osamu, Fukuda, Shota, Shimada, Kenei, Nao, Tomoko, Tanabe, Kengo, Mochizuki, Teruhito, Kurata, Akira, Morishita, Hiroshi, Matsumoto, Naoya, Ohta, Hiroshi, Yamamoto, Hideya, Kihara, Yasuki, Kitagawa, Toshiro, Ohashi, Norihiko, Kunita, Eiji, Iwanaga, Yoshitaka, Kobuke, Kazuhiro, Miyazaki, Shunichi, Kawasaki, Tomohiro, Daida, Hiroyuki, Fujii, Takashi, Sato, Aki, Okimoto, Tomokazu, and Kuribayashi, Sachio

Published
2018
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20. 18F-sodium fluoride positron emission tomography following coronary computed tomography angiography in predicting long-term coronary events: a 5-year follow-up study.

Author

Kitagawa, Toshiro, Sasaki, Ko, Fujii, Yuto, Ikegami, Yuki, Tatsugami, Fuminari, Awai, Kazuo, Hirokawa, Yutaka, and Nakano, Yukiko

Abstract

Purpose: The predictive value of 18F-sodium fluoride (18F-NaF) positron emission tomography (PET) in combination with coronary computed tomography (CT) angiography (CCTA) for future coronary events has attracted interest. We evaluated the potential of 18F-NaF PET/CT following CCTA to predict major coronary events (MACE) during a 5-year follow-up period. Methods: Forty patients with coronary atherosclerotic lesions detected on CCTA underwent 18F-NaF PET/CT examination. Each lesion was evaluated for luminal stenosis and high-risk plaque (HRP) with < 30 Hounsfield units and a > 1.1 remodeling index on CCTA. Focal 18F-NaF uptake in each lesion was quantified using the maximum tissue-to-background ratio (TBRmax), and the maximum TBRmax per patient (M-TBRmax) was determined. We followed MACE (cardiac death, acute coronary syndrome, and/or coronary revascularization > 6 months after 18F-NaF PET/CT) for 5 years. Results: In total, 142 coronary lesions were analyzed. Eleven patients experienced any MACE. Patients with MACE showed a higher M-TBRmax than those without (1.40 ±.19 vs. 1.18 ±.18, P =.0011), and the optimal M-TBRmax cutoff to predict MACE was 1.29. Patients with M-TBRmax of ≥ 1.29 had a higher risk of MACE than those with lower values (P =.012, log-rank test), whereas patients with obstructive stenosis and those with HRP did not. Multivariate Cox proportional analysis adjusted for age, sex, coronary risk factors, and CCTA findings showed that M-TBRmax of ≥ 1.29 remained an independent predictor of 5-year MACE (hazard ratio, 5.4; 95% confidence interval, 1.1–25.4; P =.034). Conclusion: 18F-NaF PET/CT following CCTA provides useful strategies to predict 5-year MACE. [ABSTRACT FROM AUTHOR]

Published
2023
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22. Endothelial Function Is Preserved in Patients with Wild-Type Transthyretin Amyloid Cardiomyopathy

Author

Hashimoto, Yu, primary, Yamaji, Takayuki, additional, Kitagawa, Toshiro, additional, Nakano, Yukiko, additional, Kajikawa, Masato, additional, Yoshimura, Kenichi, additional, Chayama, Kazuaki, additional, Goto, Chikara, additional, Tanigawa, Syunsuke, additional, Mizobuchi, Aya, additional, Harada, Takahiro, additional, Yusoff, Farina Mohamad, additional, Kishimoto, Shinji, additional, Maruhashi, Tatsuya, additional, Fujita, Asuka, additional, Uchiki, Toshio, additional, Nakashima, Ayumu, additional, and Higashi, Yukihito, additional

Published
2023
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24. The reliability and utility of on-site CT-derived fractional flow reserve (FFR) based on fluid structure interactions: comparison with FFRCT based on computational fluid dynamics, invasive FFR, and resting full-cycle ratio.

Author

Fujii, Yuto, Kitagawa, Toshiro, Ikenaga, Hiroki, Tatsugami, Fuminari, Awai, Kazuo, and Nakano, Yukiko

Subjects
*COMPUTATIONAL fluid dynamics, *CORONARY arteries, *CORONARY artery disease, *COMPUTED tomography, *FLUIDS, *MUCOCUTANEOUS lymph node syndrome
Abstract

Fractional flow reserve (FFR) derived off-site by coronary computed tomography angiography (CCTA) (FFRCT) is obtained by applying the principles of computational fluid dynamics. This study aimed to validate the overall reliability of on-site CCTA-derived FFR based on fluid structure interactions (CT-FFR) and assess its clinical utility compared with FFRCT, invasive FFR, and resting full-cycle ratio (RFR). We calculated the CT-FFR for 924 coronary vessels in 308 patients who underwent CCTA for clinically suspected coronary artery disease. Of these patients, 35 patients with at least one obstructive stenosis (> 50%) detected on CCTA underwent both CT-FFR and FFRCT for further investigation. Furthermore, 24 and 20 patients underwent invasive FFR and RFR in addition to CT-FFR, respectively. The inter-observer correlation (r) of CT-FFR was 0.93 (95% confidence interval [CI] 0.85–0.97, P < 0.0001) with a mean absolute difference of − 0.0042 (limits of agreement − 0.073, 0.064); 97.3% of coronary arteries without obstructive lesions on CCTA had negative results for ischemia on CT-FFR (> 0.80). The correlation coefficient between CT-FFR and FFRCT for 105 coronary vessels was 0.87 (95% CI 0.82–0.91, P < 0.0001) with a mean absolute difference of − 0.012 (limits of agreement − 0.12, 0.10). CT-FFR correlated well with both invasive FFR (r = 0.66, 95% CI 0.36–0.84, P = 0.0003) and RFR (r = 0.78, 95% CI 0.51–0.91, P < 0.0001). These data suggest that CT-FFR can potentially substitute for FFRCT and correlates closely with invasive FFR and RFR with high reproducibility. Our findings should be proven by further clinical investigation in a larger cohort. [ABSTRACT FROM AUTHOR]

Published
2023
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27. Development and appropriateness of a scoring method for International Classification of Functioning, Disabilities, and Health assessment in older patients with heart failure: a Delphi survey of expert panel in Japan

Author

Shiota, Shigehito, primary, Kitagawa, Toshiro, additional, Goto, Naoya, additional, Fujisita, Hironori, additional, Tamekuni, Yurika, additional, Nakayama, Susumu, additional, Mio, Naoki, additional, Kanai, Kana, additional, Naka, Makiko, additional, Yamaguchi, Mizuho, additional, Mochizuki, Mariko, additional, Ochikubo, Hiroyuki, additional, Hidaka, Takayuki, additional, Yasunobu, Yuji, additional, Nakano, Yukiko, additional, Kihara, Yasuki, additional, and Kimura, Hiroaki, additional

Published
2022
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30. A longitudinal pilot study to assess temporal changes in coronary arterial 18F-sodium fluoride uptake.

Author

Kitagawa, Toshiro, Sasaki, Ko, Fujii, Yuto, Tatsugami, Fuminari, Awai, Kazuo, Hirokawa, Yutaka, and Nakano, Yukiko

Abstract

Purpose: How coronary arterial 18F-sodium fluoride (18F-NaF) uptake on positron emission tomography changes over the long term and what clinical factors impact the changes remain unclear. We sought to investigate the topics in this study. Methods: We retrospectively studied 15 patients with ≥1 coronary atherosclerotic lesion/s detected on cardiac computed tomography who underwent baseline and follow-up (interval of >3 years) 18F-NaF positron emission tomography/computed tomography scans. Focal 18F-NaF uptake in each lesion was quantified using maximum tissue-to-background ratio (TBRmax). The temporal change in TBRmax was assessed using a ratio of follow-up to baseline TBRmax (R-TBRmax). Results: A total of 51 lesions were analyzed. Mean R-TBRmax was 0.96 ± 0.21. CT-based lesion features (location, obstructive stenosis, plaque types, features of high-risk plaque) did not correlate with an increase in R-TBRmax. In multivariate analysis, baseline TBRmax significantly correlated with higher follow-up TBRmax (β = 0.57, P < 0.0001), and the presence of diabetes mellitus significantly correlated with both higher follow-up TBRmax (β = 0.34, P = 0.001) and elevated R-TBRmax (β = 0.40, P = 0.003). Conclusion: Higher coronary arterial 18F-NaF uptake is likely to remain continuously high. Diabetes mellitus affects the long-term increase in coronary arterial 18F-NaF uptake. [ABSTRACT FROM AUTHOR]

Published
2023
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38. Innovative atherosclerosis imaging using 18F-NaF PET/CT: Its clinical potential.

Author

Kitagawa, Toshiro and Nakano, Yukiko

Abstract

In addition, intense SP 18 sp F-NaF uptake was shown in recently ruptured coronary plaques in patients with acute myocardial infarction.[5] These points highlight the potential of SP 18 sp F-NaF PET imaging as an innovative approach to monitoring atherosclerosis. For example, the step-by-step approach using coronary CT and SP 18 sp F-NaF PET/CT may be useful for identifying coronary atherosclerotic lesions and patients at high risk for coronary artery disease, and SP 18 sp F-NaF PET/CT would play a role as molecular imaging modality for coronary artery disease (Figure 2). They found that in noncalcified arterial walls, SP 18 sp F-NaF uptake is colocalized with an increased CT density and related to the presence of initial calcium deposition, whereas in calcified plaques, SP 18 sp F-NaF uptake is a harbinger of future lesion growth. In imaging of coronary arteries, SP 18 sp F-NaF tracer, unlike SP 18 sp F-fluorodeoxyglucose ( SP 18 sp F-FDG), is not taken up physiologically in the myocardium; therefore, coronary atherosclerotic lesions can be specifically detected and assessed using SP 18 sp F-NaF PET/CT. [Extracted from the article]

Published
2022
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39. The International Classification of Functioning, Disabilities, and Health Categories Necessary for Care Planning for Older Patients with Heart Failure: A Survey of Care Managers in Japan

Author

Shiota, Shigehito, primary, Kitagawa, Toshiro, additional, Hidaka, Takayuki, additional, Goto, Naoya, additional, Mio, Naoki, additional, Kanai, Kana, additional, Naka, Makiko, additional, Togino, Hiroko, additional, Mochizuki, Mariko, additional, Ochikubo, Hiroyuki, additional, Nakano, Yukiko, additional, Kihara, Yasuki, additional, and Kimura, Hiroaki, additional

Published
2021
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40. Selection of Comprehensive Assessment Categories Based on the International Classification of Functioning, Disability, and Health for Elderly Patients with Heart Failure: A Delphi Survey among Registered Instructors of Cardiac Rehabilitation

Author

Shiota, Shigehito, primary, Naka, Makiko, additional, Kitagawa, Toshiro, additional, Hidaka, Takayuki, additional, Mio, Naoki, additional, Kanai, Kana, additional, Mochizuki, Mariko, additional, Kimura, Hiroaki, additional, and Kihara, Yasuki, additional

Published
2021
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