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38 results on '"Kitagawa, Jun-Ichi"'

5. Monitoring System for the Gold Target by Radiation Detectors in Hadron Experimental Facility at J-PARC

Author

Muto Ryotaro, Agari Keizo, Aoki Kazuya, Bessho Kotaro, Hagiwara Masayuki, Hirose Erina, Ieiri Masaharu, Iwasaki Ruri, Katoh Yohji, Kitagawa Jun-ichi, Minakawa Michifumi, Morino Yuhei, Saito Kiwamu, Sato Yoshinori, Sawada Shin’ya, Shirakabe Yoshihisa, Suzuki Yoshihiro, Takahashi Hitoshi, Tanaka Kazuhiro, Toyoda Akihisa, Watanabe Hiroaki, and Yamanoi Yutaka

Subjects
Physics, QC1-999
Abstract

At the Hadron Experimental Facility in J-PARC, we inject a 30-GeV proton beam into a gold target to produce secondary particle beams required for various particle and nuclear physics experiments. The gold target is placed in a hermetic chamber, and helium gas is circulated in the chamber to monitor the soundness of the target. The radioactivity in helium gas is continuously monitored by gamma-ray detectors such as a germanium detector and a NaI(Tl) detector. Beam operations with those target-monitoring systems were successfully performed from April to June and October to December 2015, and from May to June 2016. In this paper, the details of the helium gas circulation system and gamma-ray detectors and the analysis results of the obtained gamma-ray spectra are reported.

Published
2017
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10. Pharyngeal branch of the glossopharyngeal nerve plays a major role in reflex swallowing from the pharynx

Author

Kitagawa, Jun-Ichi, Shingai, Tomio, Takahashi, Yoshihiro, and Yamada, Yoshiaki

Subjects
Physiology -- Research, Electric stimulation -- Physiological aspects, Pharynx -- Physiological aspects, Deglutition -- Physiological aspects, Biological sciences
Abstract

Mechanical stimulation of the pharyngeal areas readily elicits reflex swallowing. However, it is much more difficult for electrical stimulation of the glossopharyngeal nerve (GPN) to evoke reflex swallowing than it is for stimulation of the superior laryngeal nerve (SLN) to do so. These paradoxical findings remain unexplained; hence, the main purpose of this study was to explain this contradiction by using a urethane-anesthetized rat. Mechanical stimulation easily elicited reflex swallowing from the pharynx. The posterior pillars, posterior pharyngeal wall, and the soft palate of the rat were extremely reflexogenic areas for swallowing. Sectioning the pharyngeal branch of the GPN (GPN-ph), however, eliminated the swallowing reflex from these areas. In contrast, sectioning the lingual branch of the GPN had no effect on the elicitation of swallowing. Electrical stimulation of the GPN-ph and SLN elicited sequentially occurring swallows. The relationship between stimulus frequency and the latency of swallowing for the GPN-ph was approximately the same as that for the SLN. These results indicate that the GPN-ph plays a major role in the initiation of reflex swallowing from the pharynx in rats. superior laryngeal nerve; pharyngeal reflex; deglutition; pharyngeal plexus

Published
2002

14. Production of Radionuclides in the Cooling Water for Electromagnetic Horns at the J-PARC Neutrino Experimental Facility

Author

Bessho, Kotaro, primary, Hagiwara, Masayuki, additional, Matsumura, Hiroshi, additional, Kitagawa, Jun-ichi, additional, Takahashi, Kazutoshi, additional, Takahashi, Asako, additional, Masumoto, Kazuyoshi, additional, Monjushiro, Hideaki, additional, Oyama, Yuichi, additional, Sekiguchi, Tetsuro, additional, and Yamada, Yoshikazu, additional

Published
2015
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15. Investigation on Radionuclides Released in the Radioactive Material Leak Incident at the J-PARC Hadron Experimental Facility

Author

Hagiwara, Masayuki, primary, Saito, Kiwamu, additional, Numajiri, Masaharu, additional, Takahashi, Kazutoshi, additional, Kitagawa, Jun-ichi, additional, Matsumura, Hiroshi, additional, Sanami, Toshiya, additional, Miura, Taichi, additional, Masumoto, Kazuyoshi, additional, Ieiri, Masaharu, additional, Sato, Yoshinori, additional, and Toyoda, Akihisa, additional

Published
2015
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19. A phase II study of rituximab combined with pirarubicin–cyclophosphamide, vincristine and prednisolone regimen as first-line therapy for patients with indolent B-cell lymphoma

Author

Tsurumi, Hisashi, primary, Hara, Takeshi, additional, Goto, Naoe, additional, Kitagawa, Jun-Ichi, additional, Kanemura, Nobuhiro, additional, Yoshikawa, Takeshi, additional, Kasahara, Senji, additional, Goto, Hideko, additional, Fukuno, Kenji, additional, Yamada, Toshiki, additional, Sawada, Michio, additional, Shimizu, Masahito, additional, Takahashi, Takeshi, additional, Takami, Tsuyoshi, additional, and Moriwaki, Hisataka, additional

Published
2011
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20. Phase II study of the tetrahydropyranyl adriamycin–cyclophosphamide, vincristine, and prednisolone regimen combined with rituximab as first-line treatment for elderly patients with diffuse large B-cell lymphoma

Author

Kasahara, Senji, primary, Hara, Takeshi, additional, Tsurumi, Hisashi, additional, Goto, Naoe, additional, Kitagawa, Jun-Ichi, additional, Kanemura, Nobuhiro, additional, Yoshikawa, Takeshi, additional, Goto, Hideko, additional, Fukuno, Kenji, additional, Yamada, Toshiki, additional, Sawada, Michio, additional, Takahashi, Takeshi, additional, Takami, Tsuyoshi, additional, and Moriwaki, Hisataka, additional

Published
2011
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21. Long-term Survival of a Patient with Splenic Angiosarcoma after Resection, High-dose Chemotherapy, and Autologous Peripheral Blood Stem Cell Transplantation

Author

Hara, Takeshi, primary, Tsurumi, Hisashi, additional, Kasahara, Senji, additional, Ogawa, Kengo, additional, Takada, Jun, additional, Imai, Kenji, additional, Takai, Koji, additional, Kitagawa, Jun-ichi, additional, Kiyama, Shigeru, additional, Imai, Naoki, additional, Oyama, Masami, additional, Takami, Tsuyoshi, additional, and Moriwaki, Hisataka, additional

Published
2010
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22. Phase II study of Rituximab combined with THP-COP as first-line therapy for patients younger than 70 years with diffuse large B cell lymphoma

Author

Hara, Takeshi, primary, Tsurumi, Hisashi, additional, Goto, Naoe, additional, Kitagawa, Jun-ichi, additional, Kanemura, Nobuhiro, additional, Yoshikawa, Takeshi, additional, Kasahara, Senji, additional, Goto, Hideko, additional, Fukuno, Kenji, additional, Yamada, Toshiki, additional, Sawada, Michio, additional, Yasuda, Ichiro, additional, Katsumura, Naoki, additional, Takahashi, Takeshi, additional, Takami, Tsuyoshi, additional, and Moriwaki, Hisataka, additional

Published
2009
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23. Serum-soluble interleukin-2 receptor (sIL-2R) is an extremely strong prognostic factor for patients with peripheral T-cell lymphoma, unspecified (PTCL-U)

Author

Kitagawa, Jun-ichi, primary, Hara, Takeshi, additional, Tsurumi, Hisashi, additional, Goto, Naoe, additional, Kanemura, Nobuhiro, additional, Yoshikawa, Takeshi, additional, Kasahara, Senji, additional, Yamada, Toshiki, additional, Sawada, Michio, additional, Takahashi, Takeshi, additional, Shimizu, Masahito, additional, Takami, Tsuyoshi, additional, and Moriwaki, Hisataka, additional

Published
2008
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24. Immunoproliferative Small Intestinal Disease with Protein Loss Complicated with Duodenal T Cell Lymphoma during Progression

Author

Hara, Takeshi, primary, Tsurumi, Hisashi, additional, Kato, Tomohiro, additional, Imao, Yasuyuki, additional, Kojima, Yasushi, additional, Kojima, Keishi, additional, Kitagawa, Jun-ichi, additional, Katsumura, Naoki, additional, Araki, Hiroshi, additional, Takami, Tsuyoshi, additional, and Moriwaki, Hisataka, additional

Published
2008
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25. Continuous drip infusion of low dose cytarabine and etoposide with granulocyte colony-stimulating factor for elderly patients with acute myeloid leukaemia ineligible for intensive chemotherapy

Author

Kanemura, Nobuhiro, primary, Tsurumi, Hisashi, additional, Kasahara, Senji, additional, Hara, Takeshi, additional, Yamada, Toshiki, additional, Sawada, Michio, additional, Goto, Naoe, additional, Kitagawa, Jun-ichi, additional, Shimizu, Masahito, additional, Oyama, Masami, additional, and Moriwaki, Hisataka, additional

Published
2008
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31. Vertical distribution and formation analysis of the I, Cs, Te, and Ag from the Fukushima Dai-ichi Nuclear Power Plant in the beach soil.

Author

Satou, Yukihiko, Sueki, Keisuke, Sasa, Kimikazu, Kitagawa, Jun-ichi, Ikarashi, Satoshi, and Kinoshita, Norikazu

Subjects
FUKUSHIMA Nuclear Accident, Fukushima, Japan, 2011, VERTICAL distribution (Aquatic biology), GEOLOGIC hot spots, CESIUM content of soils, SENDAI Earthquake, Japan, 2011
Abstract

We have investigated vertical distributions of Ag, I, Te, and Cs and existence in beach soil collected three months after the Great East Japan Earthquake. All the nuclides passed through tsunami deposit and original beach soil, then reached fine particle layer lying beneath them in the three months. Moreover, depth profiles of all the nuclides did not exhibit exponential decrease. Behavior of I, Te, and Cs were explained with distribution coefficients ( K) but that of Ag was not explained. Particulate form was observed for the Cs; number of the particle was proportional to the Cs concentration in the soil sample. [ABSTRACT FROM AUTHOR]

Published
2015
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35. Volcanic ash falls from the Usu 2000 eruption and situation at the source area.

Author

TAKARADA, Shinji, primary, YOSHIMOTO, Mitsuhiro, additional, KITAGAWA, Jun-ichi, additional, HIRAGA, Naoto, additional, YAMAMOTO, Takahiro, additional, KAWANABE, Yoshihisa, additional, TAKADA, Akira, additional, NAKANO, Shun, additional, HOSHIZUMI, Hideo, additional, MIYAGI, Isoji, additional, NISHIMURA, Yuichi, additional, MIURA, Daisuke, additional, HIROSE, Wataru, additional, ISHIMARU, Satoshi, additional, KAKIHARA, Yasuyuki, additional, ENDO, Yuji, additional, YAHATA, Masahiro, additional, NOROTA, Susumu, additional, NIIDA, Kiyoaki, additional, ISHIZUKA, Yoshihiro, additional, KUDO, Takashi, additional, AIZAWA, Koji, additional, HONMA, Hiroki, additional, EGUSA, Masamichi, additional, ISHII, Eiichi, additional, and TAKAHASHI, Ryo, additional

Published
2001
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37. A phase II study of rituximab combined with pirarubicin-cyclophosphamide, vincristine and prednisolone regimen as first-line therapy for patients with indolent B-cell lymphoma.

Author

Tsurumi, Hisashi, Hara, Takeshi, Goto, Naoe, Kitagawa, Jun-Ichi, Kanemura, Nobuhiro, Yoshikawa, Takeshi, Kasahara, Senji, Goto, Hideko, Fukuno, Kenji, Yamada, Toshiki, Sawada, Michio, Shimizu, Masahito, Takahashi, Takeshi, Takami, Tsuyoshi, and Moriwaki, Hisataka

Subjects
RITUXIMAB, ANTHRACYCLINES, DOXORUBICIN, DRUG efficacy, DRUG side effects, CLINICAL trials
Abstract

The anthracycline drug pirarubicin (tetrahydropyranyl-adriamycin [THP]) apparently has been reported to show fewer cardiotoxic effects than doxorubicin. We have previously described the effectiveness of the R-THP-COP regimen comprising rituximab, cyclophosphamide, pirarubicin, vincristine and prednisolone in patients with diffuse large B-cell lymphoma. We conducted a phase II study to determine the effectiveness of a regimen incorporating rituximab (R-THP-COP) for patients with previously untreated advanced-stage indolent CD20-positive B-cell lymphoma according to the Working Formulation and World Health Organization classification. Four to six courses of the regimen were administered every 3 weeks in 50 patients. The complete remission rate was 57%, while the 3-year overall survival rate was 92%. Regimen-related death was not observed. The R-THP-COP regimen appears very effective for patients with previously untreated advanced-stage indolent CD20-positive B-cell lymphoma. The present results indicate the need for randomized trials of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone) and R-THP-COP among patients with CD20-positive indolent lymphoma. [ABSTRACT FROM AUTHOR]

Published
2012
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38. A comparison of voluntary salt-intake behavior in Nax-gene deficient and wild-type mice with reference to peripheral taste inputs

Author

Watanabe, Uno, Shimura, Tsuyoshi, Sako, Noritaka, Kitagawa, Jun-ichi, Shingai, Tomio, Watanabe, Eiji, Noda, Masaharu, and Yamamoto, Takashi

Subjects
*HOMEOSTASIS, *DRINKING behavior, *ELECTROPHYSIOLOGY
Abstract

The Nax channel, a subfamily of voltage-gated sodium channels, is thought to be a specific sodium receptor in the central nervous system. Our previous study revealed that Nax-gene-deficient mice consumed excessive amounts of NaCl even under water-deprived conditions. In the present study, to investigate whether the peripheral taste inputs are involved in the abnormal intake of salt in Nax-deficient mice (homo), voluntary intake of various taste solutions in homo and wild-type mice (wild) was examined under non-deprived conditions. Homo showed a higher preference for 0.15 M NaCl solution than wild. Preference ratios for other basic tastants were identical between groups. Transection of the chorda tympani (CT) or the glossopharyngeal (GP) nerve had little effect on salt-intake behavior in homo and wild. Although combined transection of the superior laryngeal (SL) and GP nerves decreased NaCl intake in homo but not in wild, there were no differences in preference ratios for NaCl in homo before and after SL+GP transection. On the other hand, preference ratios for NaCl in wild tended to increase after combined SL and GP transection. Consequently, preference ratios for NaCl after SL+GP transection were no different between homo and wild. While electrophysiological responses of the CT and the GP to various taste solutions were indistinguishable between homo and wild, those of the SL to NaCl in homo were smaller than those in wild only at lower concentrations (0.01 and 0.03 M). Thus, chemosensory inputs from the oro-pharyngeal regions had little effect on abnormal salt intake in homo, if any. From these results, it is suggested that the higher preference for NaCl in homo is mainly due to the lack of Nax channels in the central nervous system. [Copyright &y& Elsevier]

Published
2003
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