12 results on '"Kiss, Stephan"'
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2. bTUNED : transcutaneous tibial nerve stimulation for neurogenic lower urinary tract
- Author
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Stalder, Stephanie A., primary, Gross, Oliver, additional, Anderson, Collene E., additional, Bachmann, Lucas M., additional, Baumann, Sarah, additional, Birkhäuser, Veronika, additional, Bywater, Mirjam, additional, del Popolo, Giulio, additional, Engeler, Daniel S., additional, Agrò, Enrico Finazzi, additional, Friedl, Susanne, additional, Grilo, Nuno, additional, Kiss, Stephan, additional, Koschorke, Miriam, additional, Leitner, Lorenz, additional, Liechti, Martina D., additional, Mehnert, Ulrich, additional, Musco, Stefania, additional, Sadri, Helen, additional, Stächele, Lara, additional, Tornic, Jure, additional, van der Lely, Stéphanie, additional, Wyler, Stephen, additional, and Kessler, Thomas M., additional
- Published
- 2023
- Full Text
- View/download PDF
3. Urodynamics Are Essential to Predict the Risk for Upper Urinary Tract Damage after Acute Spinal Cord Injury
- Author
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Birkhäuser, Veronika; https://orcid.org/0000-0002-6646-7266, Anderson, Collene E; https://orcid.org/0000-0002-4350-6816, Kozomara, Marko; https://orcid.org/0000-0001-5126-9331, Bywater, Mirjam, Gross, Oliver; https://orcid.org/0000-0002-3330-5623, Kiss, Stephan, Knüpfer, Stephanie C; https://orcid.org/0000-0002-2914-1451, Koschorke, Miriam; https://orcid.org/0000-0001-5667-0474, Leitner, Lorenz; https://orcid.org/0000-0001-5764-3494, Mehnert, Ulrich; https://orcid.org/0000-0001-7963-8477, Sadri, Helen, Sammer, Ulla, Stächele, Lara; https://orcid.org/0000-0002-9723-0595, Tornic, Jure; https://orcid.org/0000-0002-1831-4783, Liechti, Martina D; https://orcid.org/0000-0002-3024-0975, Brinkhof, Martin W G; https://orcid.org/0000-0002-9319-665X, Kessler, Thomas M; https://orcid.org/0000-0002-1991-5919, Birkhäuser, Veronika; https://orcid.org/0000-0002-6646-7266, Anderson, Collene E; https://orcid.org/0000-0002-4350-6816, Kozomara, Marko; https://orcid.org/0000-0001-5126-9331, Bywater, Mirjam, Gross, Oliver; https://orcid.org/0000-0002-3330-5623, Kiss, Stephan, Knüpfer, Stephanie C; https://orcid.org/0000-0002-2914-1451, Koschorke, Miriam; https://orcid.org/0000-0001-5667-0474, Leitner, Lorenz; https://orcid.org/0000-0001-5764-3494, Mehnert, Ulrich; https://orcid.org/0000-0001-7963-8477, Sadri, Helen, Sammer, Ulla, Stächele, Lara; https://orcid.org/0000-0002-9723-0595, Tornic, Jure; https://orcid.org/0000-0002-1831-4783, Liechti, Martina D; https://orcid.org/0000-0002-3024-0975, Brinkhof, Martin W G; https://orcid.org/0000-0002-9319-665X, and Kessler, Thomas M; https://orcid.org/0000-0002-1991-5919
- Abstract
We used clinical parameters to develop a prediction model for the occurrence of urodynamic risk factors for upper urinary tract (UUT) damage during the first year after acute spinal cord injury (SCI). A total of 97 patients underwent urodynamic investigation at 1, 3, 6, and 12 months after acute SCI, within the framework of a population-based longitudinal study at a single university SCI center. Candidate predictors included demographic characteristics and neurological and functional statuses 1 month after SCI. Outcomes included urodynamic risk factors for UUT damage: detrusor overactivity combined with detrusor sphincter dyssynergia, maximum storage detrusor pressure (pDetmax) ≥ 40 cmH$_{2}$O, bladder compliance < 20 mL/cmH$_{2}$O, and vesicoureteral reflux. Multivariable logistic regression was used for the prediction model development and internal validation, using the area under the receiver operating curve (aROC) to assess model discrimination. Two models showed fair discrimination for pDetmax ≥ 40 cmH$_{2}$O: (i) upper extremity motor score and sex, aROC 0.79 (95% CI: 0.69-0.89), C-statistic 0.78 (95% CI: 0.69-0.87), and (ii) neurological level, American Spinal Injury Association Impairment Scale grade, and sex, aROC 0.78 (95% CI: 0.68-0.89), C-statistic 0.76 (95% CI: 0.68-0.85). We identified two models that provided fair predictive values for urodynamic risk factors of UUT damage during the first year after SCI. Pending external validation, these models may be useful for clinical trial planning, although less so for individual-level patient management. Therefore, urodynamics remains essential for reliably identifying patients at risk of UUT damage.
- Published
- 2023
4. bTUNED: transcutaneous tibial nerve stimulation for neurogenic lower urinary tract dysfunction
- Author
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Stalder, Stephanie A; https://orcid.org/0000-0002-7914-8264, Gross, Oliver; https://orcid.org/0000-0002-3330-5623, Anderson, Collene E; https://orcid.org/0000-0002-4350-6816, Bachmann, Lucas M; https://orcid.org/0000-0002-9868-154X, Baumann, Sarah, Birkhäuser, Veronika; https://orcid.org/0000-0002-6646-7266, Bywater, Mirjam, Del Popolo, Giulio; https://orcid.org/0000-0002-1202-6078, Engeler, Daniel S; https://orcid.org/0000-0003-1383-4701, Agrò, Enrico Finazzi; https://orcid.org/0000-0002-0308-8824, Friedl, Susanne; https://orcid.org/0000-0001-8686-8537, Grilo, Nuno; https://orcid.org/0000-0002-7188-972X, Kiss, Stephan, Koschorke, Miriam; https://orcid.org/0000-0001-5667-0474, Leitner, Lorenz; https://orcid.org/0000-0001-5764-3494, Liechti, Martina D; https://orcid.org/0000-0002-3024-0975, Mehnert, Ulrich; https://orcid.org/0000-0001-7963-8477, Musco, Stefania; https://orcid.org/0000-0001-5844-5684, Sadri, Helen, Stächele, Lara; https://orcid.org/0000-0002-9723-0595, Tornic, Jure; https://orcid.org/0000-0002-1831-4783, van der Lely, Stéphanie; https://orcid.org/0000-0002-2688-9042, Wyler, Stephen, Kessler, Thomas M; https://orcid.org/0000-0002-1991-5919, Stalder, Stephanie A; https://orcid.org/0000-0002-7914-8264, Gross, Oliver; https://orcid.org/0000-0002-3330-5623, Anderson, Collene E; https://orcid.org/0000-0002-4350-6816, Bachmann, Lucas M; https://orcid.org/0000-0002-9868-154X, Baumann, Sarah, Birkhäuser, Veronika; https://orcid.org/0000-0002-6646-7266, Bywater, Mirjam, Del Popolo, Giulio; https://orcid.org/0000-0002-1202-6078, Engeler, Daniel S; https://orcid.org/0000-0003-1383-4701, Agrò, Enrico Finazzi; https://orcid.org/0000-0002-0308-8824, Friedl, Susanne; https://orcid.org/0000-0001-8686-8537, Grilo, Nuno; https://orcid.org/0000-0002-7188-972X, Kiss, Stephan, Koschorke, Miriam; https://orcid.org/0000-0001-5667-0474, Leitner, Lorenz; https://orcid.org/0000-0001-5764-3494, Liechti, Martina D; https://orcid.org/0000-0002-3024-0975, Mehnert, Ulrich; https://orcid.org/0000-0001-7963-8477, Musco, Stefania; https://orcid.org/0000-0001-5844-5684, Sadri, Helen, Stächele, Lara; https://orcid.org/0000-0002-9723-0595, Tornic, Jure; https://orcid.org/0000-0002-1831-4783, van der Lely, Stéphanie; https://orcid.org/0000-0002-2688-9042, Wyler, Stephen, and Kessler, Thomas M; https://orcid.org/0000-0002-1991-5919
- Abstract
OBJECTIVE To present the protocol for a randomized controlled trial (RCT) evaluating the efficacy and safety of transcutaneous tibial nerve stimulation (TTNS) for refractory neurogenic lower urinary tract dysfunction (NLUTD). STUDY DESIGN AND RESULTS bTUNED (bladder and TranscUtaneous tibial Nerve stimulation for nEurogenic lower urinary tract Dysfunction) is an international multicentre, sham-controlled, double-blind RCT investigating the efficacy and safety of TTNS. The primary outcome is success of TTNS, defined as improvements in key bladder diary variables at study end compared to baseline values. The focus of the treatment is defined by the Self-Assessment Goal Achievement (SAGA) questionnaire. Secondary outcomes are the effect of TTNS on urodynamic, neurophysiological, and bowel function outcome measures, as well as the safety of TTNS. CONCLUSIONS A total of 240 patients with refractory NLUTD will be included and randomized 1:1 into the verum or sham TTNS group from March 2020 until August 2026. TTNS will be performed twice a week for 30 min during 6 weeks. The patients will attend baseline assessments, 12 treatment visits and follow-up assessments at the study end.
- Published
- 2023
5. Temporal development of unfavourable urodynamic parameters during the first year after spinal cord injury
- Author
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Anderson, Collene E; https://orcid.org/0000-0002-4350-6816, Kozomara, Marko; https://orcid.org/0000-0001-5126-9331, Birkhäuser, Veronika; https://orcid.org/0000-0002-6646-7266, Bywater, Mirjam, Gross, Oliver; https://orcid.org/0000-0002-3330-5623, Kiss, Stephan, Knüpfer, Stephanie C; https://orcid.org/0000-0002-2914-1451, Koschorke, Miriam; https://orcid.org/0000-0001-5667-0474, Leitner, Lorenz; https://orcid.org/0000-0001-5764-3494, Mehnert, Ulrich; https://orcid.org/0000-0001-7963-8477, Sadri, Helen, Sammer, Ulla, Stächele, Lara; https://orcid.org/0000-0002-9723-0595, Tornic, Jure, Liechti, Martina D; https://orcid.org/0000-0002-3024-0975, Brinkhof, Martin W G; https://orcid.org/0000-0002-9319-665X, Kessler, Thomas M; https://orcid.org/0000-0002-1991-5919, Anderson, Collene E; https://orcid.org/0000-0002-4350-6816, Kozomara, Marko; https://orcid.org/0000-0001-5126-9331, Birkhäuser, Veronika; https://orcid.org/0000-0002-6646-7266, Bywater, Mirjam, Gross, Oliver; https://orcid.org/0000-0002-3330-5623, Kiss, Stephan, Knüpfer, Stephanie C; https://orcid.org/0000-0002-2914-1451, Koschorke, Miriam; https://orcid.org/0000-0001-5667-0474, Leitner, Lorenz; https://orcid.org/0000-0001-5764-3494, Mehnert, Ulrich; https://orcid.org/0000-0001-7963-8477, Sadri, Helen, Sammer, Ulla, Stächele, Lara; https://orcid.org/0000-0002-9723-0595, Tornic, Jure, Liechti, Martina D; https://orcid.org/0000-0002-3024-0975, Brinkhof, Martin W G; https://orcid.org/0000-0002-9319-665X, and Kessler, Thomas M; https://orcid.org/0000-0002-1991-5919
- Abstract
Objectives: To describe the temporal development of and risk factors for the occurrence of unfavourable urodynamic parameters during the first year after spinal cord injury (SCI). Patients and methods: This population-based longitudinal study used data from 97 adult patients with a single-event traumatic or ischaemic SCI who underwent video-urodynamic investigation (UDI) at a university SCI centre. The first occurrences of unfavourable urodynamic parameters (detrusor overactivity combined with detrusor sphincter dyssynergia [DO-DSD], maximum storage detrusor pressure ≥40 cmH2 O, bladder compliance <20 mL/cmH2 O, vesico-ureteric reflux [VUR] and any unfavourable parameter [composite outcome]) were evaluated using time-to-event analysis. Results: The majority of the population (87/97 [90%]) had at least one unfavourable urodynamic parameter. Most unfavourable urodynamic parameters were initially identified during the 1- or 3-month UDI, including 92% of the DO-DSD (78/85), 82% of the maximum storage pressure ≥40 cmH2 O (31/38), and 100% of the VUR (seven of seven) observations. No low bladder compliance was observed. The risk of DO-DSD was elevated in patients with thoracic SCI compared to those with lumbar SCI (adjusted hazard ratio [aHR] 2.38, 95% confidence interval [CI] 1.16-4.89). Risk of maximum storage detrusor pressure ≥40 cmH2 O was higher in males than females (aHR 8.33, 95% CI 2.51-27.66), in patients with a cervical SCI compared to those with lumbar SCI (aHR 14.89, 95% CI 3.28-67.55), and in patients with AIS Grade B or C compared to AIS Grade D SCI (aHR 6.17, 95% CI 1.78-21.39). No risk factors were identified for the composite outcome of any unfavourable urodynamic parameter. Conclusions: The first UDI should take place within 3 months after SCI as to facilitate early diagnosis of unfavourable urodynamic parameters and timely treatment. Neuro-urological guidelines and individualised management strategies for patients with SCI may be strengthened by consid
- Published
- 2023
6. Neurogenic Lower Urinary Tract Dysfunction in the First Year After Spinal Cord Injury: A Descriptive Study of Urodynamic Findings
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Kozomara, Marko, primary, Birkhäuser, Veronika, additional, Anderson, Collene E., additional, Bywater, Mirjam, additional, Gross, Oliver, additional, Kiss, Stephan, additional, Knüpfer, Stephanie C., additional, Koschorke, Miriam, additional, Leitner, Lorenz, additional, Mehnert, Ulrich, additional, Sadri, Helen, additional, Sammer, Ulla, additional, Stächele, Lara, additional, Tornic, Jure, additional, Brinkhof, Martin W. G., additional, Liechti, Martina D., additional, and Kessler, Thomas M., additional
- Published
- 2023
- Full Text
- View/download PDF
7. bTUNED: transcutaneous tibial nerve stimulation for neurogenic lower urinary tract dysfunction
- Author
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Stalder, Stephanie A, Gross, Oliver, Anderson, Collene E, Bachmann, Lucas M, Baumann, Sarah, Birkhäuser, Veronika, Bywater, Mirjam, Del Popolo, Giulio, Engeler, Daniel S, Agrò, Enrico Finazzi, Friedl, Susanne, Grilo, Nuno, Kiss, Stephan, Koschorke, Miriam, Leitner, Lorenz, Liechti, Martina D, Mehnert, Ulrich, Musco, Stefania, Sadri, Helen, Stächele, Lara, Tornic, Jure, van der Lely, Stéphanie, Wyler, Stephen, Kessler, Thomas M, and University of Zurich
- Subjects
610 Medicine & health ,10046 Balgrist University Hospital, Swiss Spinal Cord Injury Center - Published
- 2023
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8. Temporal development of unfavourable urodynamic parameters during the first year after spinal cord injury
- Author
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Anderson, Collene E., primary, Kozomara, Marko, additional, Birkhäuser, Veronika, additional, Bywater, Mirjam, additional, Gross, Oliver, additional, Kiss, Stephan, additional, Knüpfer, Stephanie C., additional, Koschorke, Miriam, additional, Leitner, Lorenz, additional, Mehnert, Ulrich, additional, Sadri, Helen, additional, Sammer, Ulla, additional, Stächele, Lara, additional, Tornic, Jure, additional, Liechti, Martina D., additional, Brinkhof, Martin W.G., additional, and Kessler, Thomas M., additional
- Published
- 2022
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9. Temporal development of unfavourable urodynamic parameters during the first year after spinal cord injury.
- Author
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Anderson, Collene E., Kozomara, Marko, Birkhäuser, Veronika, Bywater, Mirjam, Gross, Oliver, Kiss, Stephan, Knüpfer, Stephanie C., Koschorke, Miriam, Leitner, Lorenz, Mehnert, Ulrich, Sadri, Helen, Sammer, Ulla, Stächele, Lara, Tornic, Jure, Liechti, Martina D., Brinkhof, Martin W.G., and Kessler, Thomas M.
- Subjects
SPINAL cord injuries ,CYSTOMETRY ,SEXUAL dimorphism - Abstract
Objectives: To describe the temporal development of and risk factors for the occurrence of unfavourable urodynamic parameters during the first year after spinal cord injury (SCI). Patients and Methods: This population‐based longitudinal study used data from 97 adult patients with a single‐event traumatic or ischaemic SCI who underwent video‐urodynamic investigation (UDI) at a university SCI centre. The first occurrences of unfavourable urodynamic parameters (detrusor overactivity combined with detrusor sphincter dyssynergia [DO‐DSD], maximum storage detrusor pressure ≥40 cmH2O, bladder compliance <20 mL/cmH2O, vesico‐ureteric reflux [VUR] and any unfavourable parameter [composite outcome]) were evaluated using time‐to‐event analysis. Results: The majority of the population (87/97 [90%]) had at least one unfavourable urodynamic parameter. Most unfavourable urodynamic parameters were initially identified during the 1‐ or 3‐month UDI, including 92% of the DO‐DSD (78/85), 82% of the maximum storage pressure ≥40 cmH2O (31/38), and 100% of the VUR (seven of seven) observations. No low bladder compliance was observed. The risk of DO‐DSD was elevated in patients with thoracic SCI compared to those with lumbar SCI (adjusted hazard ratio [aHR] 2.38, 95% confidence interval [CI] 1.16–4.89). Risk of maximum storage detrusor pressure ≥40 cmH2O was higher in males than females (aHR 8.33, 95% CI 2.51–27.66), in patients with a cervical SCI compared to those with lumbar SCI (aHR 14.89, 95% CI 3.28–67.55), and in patients with AIS Grade B or C compared to AIS Grade D SCI (aHR 6.17, 95% CI 1.78–21.39). No risk factors were identified for the composite outcome of any unfavourable urodynamic parameter. Conclusions: The first UDI should take place within 3 months after SCI as to facilitate early diagnosis of unfavourable urodynamic parameters and timely treatment. Neuro‐urological guidelines and individualised management strategies for patients with SCI may be strengthened by considering sex and SCI characteristics in the scheduling of UDIs. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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10. Obstruktive Pyelonephritis
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Kiss, Stephan, primary, Nussberger, Fabio, additional, Cantieni, Christoph, additional, Willi, Niels, additional, Voegeli, Michèle, additional, Subotic, Svetozar, additional, Maurer, Patrick, additional, and Gasser, Thomas, additional
- Published
- 2016
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11. Über die Eiweißfraktionen des normalen Harnes
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Kerekes, Medardus and Kiss, Stephan
- Published
- 1962
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12. �ber die Eiwei�fraktionen des normalen Harnes
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Kerekes, Medardus, primary and Kiss, Stephan, additional
- Published
- 1962
- Full Text
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