30 results on '"Kiropoulos L"'
Search Results
2. A systematic review and meta-analysis on the DSM-5 severity specifiers for eating disorders
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Dang, A., primary, Giles, S., additional, Fernandez-Aranda, F., additional, Kiropoulos, L., additional, and Fuller-Tyszkiewicz, M., additional
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- 2021
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3. Do women with differing levels of trait eating pathology experience daily stress and body dissatisfaction differently?
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Dang, A., primary, Fuller-Tyszkiewicz, M., additional, De La Harpe, S., additional, Rozenblat, V., additional, Giles, S., additional, Kiropoulos, L., additional, and Krug, I., additional
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- 2021
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4. Psychometric properties of the cardiac depression scale in patients with coronary heart disease
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Kiropoulos Litza A, Meredith Ian, Tonkin Andrew, Clarke David, Antonis Paul, and Plunkett Julie
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Cardiac depression scale ,Depression ,Coronary heart disease ,Validity ,Reliability ,Psychometric properties ,Psychiatry ,RC435-571 - Abstract
Abstract Background This study examined the psychometric properties of the Cardiac Depression Scale (CDS) in a sample of coronary heart disease (CHD) patients. Methods A total of 152 patients were diagnosed with coronary heart disease and were administered the CDS along with the Beck Depression Inventory- 2 (BDI-2) and the State Trait Anxiety Inventory (STAI) 3.5-months after cardiac hospitalization. Results The CDS’s factorial composition in the current sample was similar to that observed in the original scale. Varimax-rotated principal-components analyses extracted six factors, corresponding to mood, anhedonia, cognition, fear, sleep and suicide. Reliability analyses yielded internal consistency α - coefficients for the six subscales ranging from 0.62 to 0.82. The CDS showed strong concurrent validity with the BDI-II (r = 0.64). More patients were classified as severely depressed using the CDS. Both the CDS and the BDI-2 displayed significantly strong correlations with the STAI (r = 0.61 and r = 0.64), respectively. Conclusions These findings encourage the use of the CDS for measuring the range of depressive symptoms in those with CHD 3.5 months after cardiac hospitalization.
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- 2012
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5. Psychiatric comorbidity and severity in anorexia nervosa: a comparative study of the DSM-5, the ICD-11, and overvaluation of Weight/Shape severity ratings.
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Dang AB, Kiropoulos L, Castle D, Jenkins Z, Phillipou A, Rossell S, and Krug I
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This study assessed the rate of a.) the total and b.) specific psychiatric comorbidities among the three severity ratings for Anorexia Nervosa (AN): DSM-5, ICD-11 and overvaluation of weight and shape (OWS). The sample comprised 312 treatment-seeking patients with AN (mean age = 26.9). Weight and height were taken at intake to calculate BMI, the foundation for the DSM-5 and ICD-11 severity indices. The EDE-Q was used to assess OWS, and the Mini International Neuropsychiatric Interview was conducted to assess psychiatric comorbidities. For the DSM-5, the mild severity group showed a higher total number of psychiatric comorbidities, especially for panic, social anxiety, generalised anxiety, and post-traumatic stress disorders compared to the severe and extremely severe groups. ICD-11 and OWS severity groups did not significantly differ in total comorbidities, except for major depressive disorder and obsessive-compulsive disorders being more prevalent in the "significantly low BMI" ICD-11 group. The high OWS group displayed a notably higher rate of major depressive disorder than the low OWS group. The study underscores inconsistent patterns across the three severity systems, emphasising the need to recognise the current limitations of the assessed severity classification systems in AN assessment and guiding treatment.
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- 2024
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6. Australian elite sport coaches' mental health literacy of eating disorders, orthorexia, and muscle dysmorphia in athletes: A qualitative study.
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Mitchell J, Tilbrook M, Kiropoulos L, and Krug I
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- Humans, Orthorexia Nervosa, Body Image psychology, Australia, Athletes, Muscles, Health Literacy, Feeding and Eating Disorders diagnosis, Feeding and Eating Disorders therapy
- Abstract
Athletes have an increased risk of developing eating disorders (EDs) compared to non-athletes. Coaches are in a unique position to identify symptoms and promote timely support; however, research has not yet explored coaches' mental health literacy about DSM-5 EDs and related orthorexia and muscle dysmorphia conditions in elite athletes. Eighteen Australian elite sport coaches from aesthetic, weight-class, and endurance sports participated in individual semi-structured interviews to investigate their mental health literacy of EDs and related conditions. Four themes emerged from the data. Theme 1 (knowledge of EDs and related conditions) highlighted coaches' awareness of maladaptive perfectionism as a key risk factor, limited awareness of EDs without observable weight loss, and conceptualisation of EDs as a nutritional issue. Theme 2 (facilitators to managing EDs) highlighted the helpfulness of building trust with athletes, accessing support staff, emphasising body functionality, and lived experience. Theme 3 (barriers to managing EDs) highlighted coaches' challenges with communicating about body image, responding to denial, and funding constraints. Theme 4 (future ED education and training) highlighted coaches' desire for in-person, interactive training and to support junior-level coaches. These findings may assist in developing tailored educational resources to improve coaches' ability to identify and manage eating-related concerns in athletes., Competing Interests: Declaration of Competing Interest None., (Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.)
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- 2024
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7. Do risk factors differentiate DSM-5 and drive for thinness severity groups for anorexia nervosa?
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Dang AB, Kiropoulos L, Anderluh M, Collier D, Fernandez-Aranda F, Karwautz A, Treasure J, Wagner G, and Krug I
- Abstract
Background: The current study examined whether risk factors for anorexia nervosa (AN) were related to different levels of severity based on (a) the DSM-5/body mass index (BMI) and (b) drive for thinness (DT) severity ratings., Methods: The sample comprised 153 pairs of individuals with a lifetime diagnosis AN per DSM-IV criteria and their non-ED sisters (N = 306, mean age = 26.53; mean current BMI = 20.42 kg/m
2 ). The Oxford risk factor interview was used to establish AN-related risk factors. Individuals were categorised into the DSM-5 severity groups based on their lowest BMI, while the DT subscale from the eating disorder inventory-2 was used to classify individuals with AN into low and high DT groups., Results: Multinominal regression models showed similar risk factors (e.g., perfectionism, having a history of being teased about weight and shape) contributed to the development of AN using the DSM-5 and DT severity ratings. Follow-up analyses across the severity groups for both indices revealed that only childhood perfectionism was found to be more common in the extreme severe DSM-5 BMI severity group compared to the severe DSM-5 group., Conclusion: Overall, this study found little evidence for AN risk factors being related to the DSM-5 and DT severity ratings. However, given the novelty of this study, replication of the current results is warranted., (© 2024. The Author(s).)- Published
- 2024
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8. Validating and developing a shortened version of the detail and flexibility (DFlex) questionnaire for eating disorders, anxiety and depression.
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Giles S, Hughes EK, Fuller-Tyszkiewicz M, Kiropoulos L, Donnelly B, Russell J, and Krug I
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- Humans, Reproducibility of Results, Psychometrics, Anxiety Disorders diagnosis, Anxiety Disorders psychology, Surveys and Questionnaires, Depression psychology, Feeding and Eating Disorders diagnosis
- Abstract
Objective: To validate the original and a shortened version of the Detail and Flexibility (DFlex) Questionnaire., Method: Confirmatory factor analyses, internal consistency, and discriminant validity estimates were conducted within individuals with a diagnosis of an eating disorder (ED) (n = 124), an anxiety disorder and/or depression (n = 219), and a community sample (n = 852) (Part 1). Convergent validity of the DFlex through comparisons with the Autism Spectrum Quotient, Wisconsin Card Sorting Task, and Group Embedded Figures Task was undertaken within a combined ED and community sample (N = 68). Test-retest reliability of the DFlex was also examined across 2 years in a community sample (N = 85) (Part 2)., Results: The original factor structure of the DFlex was not supported. Hence, a shortened version, the DFlex-Revised, was developed. Good discriminant validity was obtained for the DFlex and DFlex-Revised, however, support for convergent validity was mixed. Finally, the 2-year test-retest reliability for the two DFlex versions was found to be low, suggesting potential malleability in construct over this timeframe., Conclusions: Further research is needed to validate the DFlex in clinical and non-clinical populations using different neurocognitive tests. Test-retest, using varied time intervals, should also be assessed., (© 2023 The Authors. European Eating Disorders Review published by Eating Disorders Association and John Wiley & Sons Ltd.)
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- 2024
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9. Early intervention for depressive symptoms in multiple sclerosis.
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Kiropoulos L
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- Humans, Depression therapy, Multiple Sclerosis complications
- Abstract
Competing Interests: LK is currently a member of the Research Management Committee (Social and Applied Grants Panel), MS Australia; a member of the Melbourne Health/Royal Melbourne Health ethics committee; a grant reviewer for the UK MS Society; chair of the Low to Negligible Risk Human Ethics Committee, University of Melbourne; and head of the Clinical Psychology Service at the MS Centre of the Royal Melbourne Hospital; and has received University of Melbourne funding for a short study leave, an MS Australia Incubator Grant (2021), and a Centre for Artificial Intelligence and Digital Ethics Seed Grant, University of Melbourne (2023).
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- 2023
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10. Body appreciation around the world: Measurement invariance of the Body Appreciation Scale-2 (BAS-2) across 65 nations, 40 languages, gender identities, and age.
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Swami V, Tran US, Stieger S, Aavik T, Ranjbar HA, Adebayo SO, Afhami R, Ahmed O, Aimé A, Akel M, Halbusi HA, Alexias G, Ali KF, Alp-Dal N, Alsalhani AB, Álvares-Solas S, Amaral ACS, Andrianto S, Aspden T, Argyrides M, Aruta JJBR, Atkin S, Ayandele O, Baceviciene M, Bahbouh R, Ballesio A, Barron D, Bellard A, Bender SS, Beydağ KD, Birovljević G, Blackburn MÈ, Borja-Alvarez T, Borowiec J, Bozogáňová M, Bratland-Sanda S, Browning MHEM, Brytek-Matera A, Burakova M, Çakır-Koçak Y, Camacho P, Camilleri VE, Cazzato V, Cerea S, Chaiwutikornwanich A, Chaleeraktrakoon T, Chambers T, Chen QW, Chen X, Chien CL, Chobthamkit P, Choompunuch B, Compte EJ, Corrigan J, Cosmas G, Cowden RG, Czepczor-Bernat K, Czub M, da Silva WR, Dadfar M, Dalley SE, Dany L, Datu JAD, Berbert de Carvalho PH, Coelho GLH, De Jesus AOS, Debbabi SH, Dhakal S, Di Bernardo F, Dimitrova DD, Dion J, Dixson B, Donofrio SM, Drysch M, Du H, Dzhambov AM, El-Jor C, Enea V, Eskin M, Farbod F, Farrugia L, Fian L, Fisher ML, Folwarczny M, Frederick DA, Fuller-Tyszkiewicz M, Furnham A, García AA, Geller S, Ghisi M, Ghorbani A, Martinez MAG, Gradidge S, Graf S, Grano C, Gyene G, Hallit S, Hamdan M, Handelzalts JE, Hanel PHP, Hawks SR, Hekmati I, Helmy M, Hill T, Hina F, Holenweger G, Hřebíčková M, Ijabadeniyi OA, Imam A, İnce B, Irrazabal N, Jankauskiene R, Jiang DY, Jiménez-Borja M, Jiménez-Borja V, Johnson EM, Jovanović V, Jović M, Jović M, Junqueira ACP, Kahle LM, Kantanista A, Karakiraz A, Karkin AN, Kasten E, Khatib S, Khieowan N, Kimong PJ, Kiropoulos L, Knittel J, Kohli N, Koprivnik M, Kospakov A, Król-Zielińska M, Krug I, Kuan G, Kueh YC, Kujan O, Kukić M, Kumar S, Kumar V, Lamba N, Lauri MA, Laus MF, LeBlanc LA, Lee HJ, Lipowska M, Lipowski M, Lombardo C, Lukács A, Maïano C, Malik S, Manjary M, Baldó LM, Martinez-Banfi M, Massar K, Matera C, McAnirlin O, Mebarak MR, Mechri A, Meireles JFF, Mesko N, Mills J, Miyairi M, Modi R, Modrzejewska A, Modrzejewska J, Mulgrew KE, Myers TA, Namatame H, Nassani MZ, Nerini A, Neto F, Neto J, Neves AN, Ng SK, Nithiya D, O J, Obeid S, Oda-Montecinos C, Olapegba PO, Olonisakin TT, Omar SS, Örlygsdóttir B, Özsoy E, Otterbring T, Pahl S, Panasiti MS, Park Y, Patwary MM, Pethö T, Petrova N, Pietschnig J, Pourmahmoud S, Prabhu VG, Poštuvan V, Prokop P, Ramseyer Winter VL, Razmus M, Ru T, Rupar M, Sahlan RN, Hassan MS, Šalov A, Sapkota S, Sarfo JO, Sawamiya Y, Schaefer K, Schulte-Mecklenbeck M, Seekis V, Selvi K, Sharifi M, Shrivastava A, Siddique RF, Sigurdsson V, Silkane V, Šimunić A, Singh G, Slezáčková A, Sundgot-Borgen C, Ten Hoor G, Tevichapong P, Tipandjan A, Todd J, Togas C, Tonini F, Tovar-Castro JC, Trangsrud LKJ, Tripathi P, Tudorel O, Tylka TL, Uyzbayeva A, Vally Z, Vanags E, Vega LD, Vicente-Arruebarrena A, Vidal-Mollón J, Vilar R, Villegas H, Vintilă M, Wallner C, White MP, Whitebridge S, Windhager S, Wong KY, Yau EK, Yamamiya Y, Yeung VWL, Zanetti MC, Zawisza M, Zeeni N, Zvaríková M, and Voracek M
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- Humans, Psychometrics, Reproducibility of Results, Factor Analysis, Statistical, Language, Surveys and Questionnaires, Body Image psychology, Gender Identity
- Abstract
The Body Appreciation Scale-2 (BAS-2) is a widely used measure of a core facet of the positive body image construct. However, extant research concerning measurement invariance of the BAS-2 across a large number of nations remains limited. Here, we utilised the Body Image in Nature (BINS) dataset - with data collected between 2020 and 2022 - to assess measurement invariance of the BAS-2 across 65 nations, 40 languages, gender identities, and age groups. Multi-group confirmatory factor analysis indicated that full scalar invariance was upheld across all nations, languages, gender identities, and age groups, suggesting that the unidimensional BAS-2 model has widespread applicability. There were large differences across nations and languages in latent body appreciation, while differences across gender identities and age groups were negligible-to-small. Additionally, greater body appreciation was significantly associated with higher life satisfaction, being single (versus being married or in a committed relationship), and greater rurality (versus urbanicity). Across a subset of nations where nation-level data were available, greater body appreciation was also significantly associated with greater cultural distance from the United States and greater relative income inequality. These findings suggest that the BAS-2 likely captures a near-universal conceptualisation of the body appreciation construct, which should facilitate further cross-cultural research., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.)
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- 2023
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11. Assessing severity in anorexia nervosa: Do the DSM-5 and an alternative severity rating based on overvaluation of weight and shape severity differ in psychological and biological correlates?
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Dang AB, Kiropoulos L, Castle DJ, Jenkins Z, Phillipou A, Rossell SL, and Krug I
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- Humans, Adult, Diagnostic and Statistical Manual of Mental Disorders, Psychopathology, Body Image, Anorexia Nervosa diagnosis
- Abstract
Objective: This study evaluated the severity ratings for anorexia nervosa (AN) in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) and an alternative severity rating based on overvaluation of weight/shape, on a range of psychological and biological variables., Method: A sample of 312 treatment-seeking patients with AN (mean age = 25.3, SD = 7.6; mean BMI = 16.8 kg/m
2 , SD = 2.4) were categorised using both DSM-5 severity levels (mild/moderate/severe/extreme) and weight/shape (low/high) overvaluation. The severity categories were compared on a range of psychological (e.g., eating psychopathology) and biological (e.g., sodium) variables., Results: Results showed that the overvaluation of weight/shape appeared better at indexing the level of severity in psychological variables among patients with AN compared to the DSM-5 severity rating with moderate to large effect sizes. Moreover, the DSM-5 mild and moderate severity groups experienced significantly higher eating and general psychopathology than the severe and extreme groups. Finally, neither the DSM-5 nor the weight/shape severity groups differed on any of the biological variables., Conclusions: This study provided no support for the DSM-5 severity rating for AN, while initial support was found for the weight/shape overvaluation approach in indexing psychological but not biological correlates., (© 2023 Eating Disorders Association and John Wiley & Sons Ltd.)- Published
- 2023
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12. The Mediating Role of Stigma, Internalized Shame, and Autonomous Motivation in the Relationship Between Depression, Anxiety, and Psychological Help-Seeking Attitudes in Multiple Sclerosis.
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Barta T and Kiropoulos L
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- Humans, Motivation, Social Stigma, Shame, Anxiety psychology, Patient Acceptance of Health Care psychology, Depression psychology, Multiple Sclerosis complications
- Abstract
Background: Depression and anxiety are commonly experienced in individuals with multiple sclerosis (MS) yet little is known about factors associated with psychological help-seeking attitudes in those with MS., Method: The current study investigated whether increased stigma related to chronic illness, internalized shame, and autonomous motivation mediated the relationship between depressive and anxiety symptoms and psychological help-seeking attitudes in individuals with MS. Two hundred fifty-four participants with MS completed an online questionnaire assessing depressive and anxiety symptoms, stigma related to chronic illness, internalized shame, autonomous motivation, and psychological help-seeking attitudes., Results: Stigma related to chronic illness, internalized shame, and autonomous motivation mediated the relationships between increased depressive symptoms and anxiety symptoms and psychological help-seeking attitudes. The study also found that higher levels of chronic illness-related stigma and internalized shame were associated with more negative psychological help-seeking attitudes and higher autonomous motivation was associated with more positive psychological help-seeking attitudes. There were no direct effects of depressive or anxiety symptoms on psychological help-seeking attitudes., Conclusion: The significant mediating roles of stigma-related chronic illness, internalized shame, and autonomous motivation indicate that these factors may be useful to include in future depression and anxiety intervention studies targeting MS populations., (© 2022. The Author(s).)
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- 2023
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13. The effects of mindfulness-based interventions on symptoms of depression, anxiety, and cancer-related fatigue in oncology patients: A systematic review and meta-analysis.
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Chayadi E, Baes N, and Kiropoulos L
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- Anxiety psychology, Anxiety therapy, Depression psychology, Depression therapy, Fatigue etiology, Fatigue psychology, Fatigue therapy, Humans, Mindfulness methods, Neoplasms complications, Neoplasms psychology, Neoplasms therapy
- Abstract
Objective: Mindfulness-based interventions (MBIs) are increasingly being integrated into oncological treatment to mitigate psychological distress and promote emotional and physical well-being. This review aims to provide the most recent evaluation of Mindfulness-Based Stress Reduction (MBSR), Mindfulness-Based Cognitive Therapy (MBCT), and Mindfulness-Based Cancer Recovery (MBCR) treatments, in reducing symptoms of depression, anxiety and CRF in oncology populations., Methods: A search using the following search terms was conducted: (mindful* OR mindfulness* OR mindfulness-based* OR MBI* OR MBCT OR MBSR OR MBCR) AND (Oncol* OR cancer OR neoplasm OR lymphoma OR carcinoma OR sarcoma) to obtain relevant publications from five databases: PsycINFO, PubMed, Embase, and MEDLINE by EC, and ProQuest Dissertations & Theses Global from January 2000 to February 2022. 36 independent studies (n = 1677) were evaluated for their overall effect sizes (using random-effects models), subgroup analyses, and quality appraisals. Evaluations were performed separately for non-randomized (K = 20, n = 784) and randomized controlled trials (K = 16, n = 893)., Results: The results showed that MBIs have significant medium effects in reducing symptoms of depression (Hedges' g = 0.43), anxiety (Hedges' g = 0.55) and CRF (Hedges' g = 0.43), which were maintained at least three months post-intervention. MBIs were also superior in reducing symptoms of anxiety (Hedges' g = 0.56), depression (Hedges' g = 0.43), and CRF (Hedges' g = 0.42) in oncology samples relative to control groups. The superiority of MBIs to control groups was also maintained at least three months post-intervention for anxiety and CRF symptoms, but not for depressive symptoms. The risk of bias of the included studies were low to moderate., Conclusions: This review found that MBIs reduced symptoms of depression, anxiety and CRF in oncology populations., Systematic Review Registration: PROSPERO: International Prospective Register of Systematic Reviews: CRD42020143286., Competing Interests: The authors have declared that no competing interests exist.
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- 2022
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14. A new integrative model for the co-occurrence of non-suicidal self-injury behaviours and eating disorder symptoms.
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Krug I, Arroyo MD, Giles S, Dang AB, Kiropoulos L, De Paoli T, Buck K, Treasure J, and Fuller-Tyszkiewicz M
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Objective: The high co-occurrence of non-suicidal self-injury (NSSI) behaviours and eating disorder (ED) symptoms suggests these conditions share common aetiological processes. We assessed a new integrative model of shared factors for NSSI and ED symptoms, where affect dysregulation, impulsivity, self-esteem, and body dissatisfaction mediated the relationship between insecure attachment and maladaptive schemas and NSSI and ED symptoms. A further aim of the study was to assess whether the model behaved similarly across a clinical eating disorder (ED) and a community sample., Method: 123 females with a lifetime ED diagnosis and 531 female individuals from the community completed an online survey, which included measures assessing the variables of interest. A cross-sectional single time point analysis was used., Results: Invariance testing indicated that the model was structurally non-invariant (different across groups). The proposed integrative model was a good fit for the ED group, but for the community sample only a revised model reached an acceptable fit. Both attachment and maladaptive schemas, included early in the model, were implicated in the pathways leading to ED and NSSI symptoms in the ED and community groups. In the community group, impulsivity, a mediator, was a shared predictor for NSSI and bulimic symptoms. No other mediating variables were shared by NSSI and ED symptoms in the two groups. Overall, the proposed model explained slightly more variance for the ED group relative to the community group in drive for thinness (R
2 = .57 vs .51) and NSSI (R2 = .29 vs .24) but less variance in bulimic symptoms (R2 = .33 vs .39)., Conclusion: We conclude that the current model provides only limited support for explaining the comorbidity between NSSI and ED symptoms. It is vital to consider both common (e.g., attachment and maladaptive schemas) and specific factors (e.g., impulsivity) to better understand the pathways that lead to the co-occurrence of NSSI and ED symptoms. A new integrative model assessed whether emotion dysregulation, impulsivity, self-esteem, and body dissatisfaction were mediators in the relationship between insecure attachment and maladaptive beliefs about the world and the self and subsequent eating disorder and self-harm symptoms. A further aim was to assess whether the proposed model differed between a clinical eating disorder and a community sample. All participants were female and included 123 patients with a lifetime eating disorder and 531 individuals from the community. Participating individuals completed an online survey at one timepoint, which included measures assessing the variables of interest. The findings of the current study indicated that the proposed model was a good match for the clinical eating disorder sample, but for the community sample only a revised model yielded acceptable statistical fit. Both insecure attachment and maladaptive beliefs about the world and the self, included early in the model, were indirectly related to eating disorder and self-harm symptoms for both the eating disorder and the community groups. Impulsivity, a mediator, was the only shared predictor for self-harm, and bulimic symptoms in the community group. We conclude that the current model provides only limited support for explaining the comorbidity between self-harming behaviours and disordered eating symptoms., (© 2021. The Author(s).)- Published
- 2021
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15. Self-concept, illness acceptance and depressive and anxiety symptoms in people with multiple sclerosis.
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Kiropoulos L, Ward N, and Rozenblat V
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- Anxiety, Depression, Humans, Self Concept, Surveys and Questionnaires, Multiple Sclerosis
- Abstract
Little research has examined the relationship between self-concept and depressive and anxiety symptoms and whether this is moderated by illness acceptance in individuals with multiple sclerosis. Results of an online self-report survey completed by 515 individuals with multiple sclerosis revealed that self-concept was negatively associated with depressive and anxiety symptoms with illness acceptance moderating the association such that individuals with highest self-concept and illness acceptance had the lowest levels of depressive and anxiety symptoms. Findings lend support to psychological interventions that focus on increasing illness acceptance and fostering positive self-concept in individuals with multiple sclerosis.
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- 2021
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16. Correction to: Comparison of the effectiveness of a tailored cognitive behavioural therapy with a supportive listening intervention for depression in those newly diagnosed with multiple sclerosis (the ACTION-MS trial): protocol of an assessor-blinded, active comparator, randomised controlled trial.
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Kiropoulos L, Kilpatrick T, Kalincik T, Churilov L, McDonald E, Wijeratne T, Threader J, Rozenblat V, O'Brien-Simpson N, Van Der Walt A, and Taylor L
- Abstract
After publication of our article [1] the authors have notified us that three of the names have been incorrectly spelled.
- Published
- 2020
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17. Comparison of the effectiveness of a tailored cognitive behavioural therapy with a supportive listening intervention for depression in those newly diagnosed with multiple sclerosis (the ACTION-MS trial): protocol of an assessor-blinded, active comparator, randomised controlled trial.
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Kiropoulos L, Kilpatrick T, Kalincik T, Churilov L, McDonald E, Wijeratne T, Threader J, Rozenblat V, O’Brien-Simpson N, Van Der Walt A, and Taylor L
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- Adaptation, Psychological, Anxiety psychology, Australia, Depressive Disorder psychology, Fatigue, Humans, Multiple Sclerosis diagnosis, Psychotherapy methods, Quality of Life, Resilience, Psychological, Single-Blind Method, Sleep Initiation and Maintenance Disorders, Social Support, Randomized Controlled Trials as Topic, Cognitive Behavioral Therapy methods, Depressive Disorder therapy, Multiple Sclerosis psychology
- Abstract
Background: Multiple sclerosis (MS) is an unpredictable, chronic neurological disease accompanied with high rates of depression and anxiety, particularly in the early stages of diagnosis. There is evidence to suggest that cognitive behavioural therapy (CBT) is effective for the treatment of depression amongst individuals with MS; however, there is a paucity of tailored CBT interventions designed to be offered in the newly diagnosed period. This trial is the first to assess the effectiveness and cost-effectiveness of a tailored CBT intervention compared to a supportive listening (SL) intervention amongst individuals with MS who are depressed., Methods: ACTION-MS is a two-arm parallel group, assessor-blinded, active comparator, randomised controlled trial which will test whether a tailored CBT-based intervention compared to an SL intervention can reduce depression and related factors such as anxiety, fatigue, pain and sleep problems in those newly diagnosed with MS. Sixty participants who are within 5 years of having received a diagnosis of MS and scored within the mild to moderate range of depression on the Beck Depression Inventory (BDI-II) will be recruited from MS clinics located across three hospital sites in Melbourne, Australia. The primary outcome is depression severity using the BDI-II at post-assessment. Intervention satisfaction and acceptability will be assessed. A cost-effectiveness analysis will also be conducted. Data will be analysed on an intention-to-treat basis., Discussion: There is a scarcity of psychological interventions for depression targeting the newly diagnosed period. However, interventions during this time point have the potential to have a major impact on the mental and physical wellbeing of those newly diagnosed with MS. The current trial will provide data on the effectiveness of a tailored CBT intervention for the treatment of depression in those newly diagnosed with MS. Findings will also provide effect size estimates that can be used to power a later-stage multi-centre trial of treatment efficacy, and will provide information on the mechanisms underlying any treatment effects and cost-effectiveness data for delivering this intervention in outpatient MS clinics., Trial Registration: ISRCTN trials registry, ISRCTN63987586. Current controlled trials. Retrospectively registered on 20 October 2017.
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- 2020
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18. Trauma and Mental Health in Resettled Refugees: Mediating Effect of Host Language Acquisition on Posttraumatic Stress Disorder, Depressive and Anxiety Symptoms.
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Kartal D, Alkemade N, and Kiropoulos L
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- Adolescent, Adult, Aged, Aged, 80 and over, Australia epidemiology, Austria epidemiology, Female, Humans, Life Change Events, Male, Middle Aged, Models, Psychological, Psychiatric Status Rating Scales, Self Report, Warfare, Young Adult, Anxiety epidemiology, Depression epidemiology, Language, Refugees psychology, Stress Disorders, Post-Traumatic epidemiology
- Abstract
This study examined the relationship between traumatic exposure, host language acquisition and mental health (posttraumatic stress, depressive and anxiety symptoms) in long-term resettled refugees. Participants included a community sample of Bosnian refugees ( N = 138, 55% male, mean age of 40 years old) that had resettled in Australia and Austria on average 18 years prior. Two mediation models were tested based on two competing theories. Model A examined whether language acquisition mediates the relationship between traumatic exposure and mental health problems experienced by refugees. Model B examined whether mental health symptoms mediate the relationship between exposure to traumatic events and the acquisition of host language. Model A fit the data well (CFI = 1.00, SRMR = .017, RMSEA < .001, χ
2 p = .526), while Model B was rejected as an acceptable model for the data (CFI = .556, SRMR = .136, RMSEA = .352). In Model A, the indirect pathway from trauma to mental health via language acquisition was significant for PTSD ( β = .067, p = .028) and anxiety symptoms ( β = .063, p = .026) but not depression symptoms ( β = .048, p = .071). Intervention strategies aimed at improving host language acquisition may be important not only in successful adaptation to daily living in the host country, but also to improve the mental health of traumatized refugees.- Published
- 2019
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19. Online Health Seeking Behaviours: What Information Is Sought by Women Experiencing Miscarriage?
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Pang PC, Temple-Smith M, Bellhouse C, Trieu VH, Kiropoulos L, Williams H, Coomarasamy A, Brewin J, Bowles A, and Bilardi J
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- Female, Health Behavior, Humans, Internet, Mothers, Pregnancy, Abortion, Spontaneous, Information Seeking Behavior
- Abstract
One in four pregnancies ends in miscarriage, a distressing event which can cause significant psychosocial impacts for many women, and yet often remains unseen and unspoken. Many would-be mothers turn to the internet for information and emotional support, and to share their experiences. In this paper, we present the results from 12 semi-structured interviews with women, investigating how and what online information they searched for at the time of miscarriage. We found that women are passive information seekers, searching for causes and preventive strategies to inform future pregnancies. Women want information presented in an easy to understand manner that is not overly clinical, and informed by credible sources. Women also seek psychological support and emotional relief through reading about others' experiences and sharing their stories online. The findings from this study provide a unique insight into the support and information needs of women, and will be used to guide the content, design and functionality of web-based technologies for women experiencing miscarriage.
- Published
- 2018
20. Depression as a risk factor for fracture in women: A 10 year longitudinal study.
- Author
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Williams LJ, Pasco JA, Jackson H, Kiropoulos L, Stuart AL, Jacka FN, and Berk M
- Subjects
- Absorptiometry, Photon, Adult, Aged, Bone Density, Case-Control Studies, Cross-Sectional Studies, Depression drug therapy, Depressive Disorder drug therapy, Female, Femur Neck diagnostic imaging, Humans, Longitudinal Studies, Middle Aged, Odds Ratio, Osteoporosis psychology, Proportional Hazards Models, Psychotropic Drugs therapeutic use, Retrospective Studies, Risk Factors, Surveys and Questionnaires, Depression complications, Depressive Disorder complications, Fractures, Bone psychology
- Abstract
Background: Previous research has demonstrated deficits in bone mineral density (BMD) among individuals with depression. While reduced BMD is a known risk for fracture, a direct link between depression and fracture risk is yet to be confirmed., Methods: A population-based sample of women participating in the Geelong Osteoporosis Study was studied using both nested case-control and retrospective cohort study designs. A lifetime history of depression was identified using a semi-structured clinical interview (SCID-I/NP). Incident fractures were identified from radiological reports and BMD was measured at the femoral neck using dual energy absorptiometry. Anthropometry was measured and information on medication use and lifestyle factors was obtained via questionnaire., Results: Among 179 cases with incident fracture and 914 controls, depression was associated with increased odds of fracture (adjusted odds ratio (OR) 1.57, 95%CI 1.04-2.38); further adjustment for psychotropic medication use appeared to attenuate this association (adjusted OR 1.52, 95%CI 0.98-2.36). Among 165 women with a history of depression at baseline and 693 who had no history of depression, depression was associated with a 68% increased risk of incident fracture (adjusted hazard ratio (HR) 1.68, 95%CI 1.02-2.76), with further adjustment for psychotropic medication use also appearing to attenuate this association (adjusted HR 1.58, 95%CI 0.95-2.61)., Limitations: Potential limitations include recall bias, unrecognised confounding and generalizability., Conclusions: This study provides both cross-sectional and longitudinal evidence to suggest that clinical depression is a risk factor for radiologically-confirmed incident fracture, independent of a number of known risk factors. If there is indeed a clinically meaningful co-morbidity between mental and bone health, potentially worsened by psychotropic medications, the issue of screening at-risk populations needs to become a priority., (Copyright © 2015 Elsevier B.V. All rights reserved.)
- Published
- 2016
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21. Effects of acculturative stress on PTSD, depressive, and anxiety symptoms among refugees resettled in Australia and Austria.
- Author
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Kartal D and Kiropoulos L
- Abstract
Background: Research indicates that exposure to war-related traumatic events impacts on the mental health of refugees and leads to higher rates of posttraumatic stress disorder (PTSD), depression, and anxiety symptoms. Furthermore, stress associated with the migration process has also been shown to impact negatively on refugees' mental health, but the extent of these experiences is highly debatable as the relationships between traumatic events, migration, and mental health outcomes are complex and poorly understood., Objective: This study aimed to examine the influence of trauma-related and post-migratory factors on symptoms of PTSD, depression, and anxiety in two samples of Bosnian refugees that have resettled in two different host nations-Austria and Australia., Method: Using multiple recruitment methods, 138 participants were recruited to complete self-report measures assessing acculturative stress, PTSD, depressive, and anxiety symptoms., Results: Hierarchical regressions indicated that after controlling for age, sex, and exposure to traumatic events, acculturative stress associated with post-migratory experiences predicted severity of PTSD and anxiety symptoms, while depressive symptoms were only predicted by exposure to traumatic events. This model, however, was only significant for Bosnian refugees resettled in Austria, as PTSD, depressive, and anxiety symptoms were only predicted by traumatic exposure in the Bosnian refugees resettled in Australia., Conclusion: These findings point toward the importance of assessing both psychological and social stressors when assessing mental health of refugees. Furthermore, these results draw attention to the influence of the host society on post-migratory adaptation and mental health of refugees. Further research is needed to replicate these findings among other refugee samples in other host nations.
- Published
- 2016
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22. Erratum to: Comparison of the acceptability and benefits of two mindfulness-based interventions in women with breast or gynecologic cancer: a pilot study.
- Author
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Stafford L, Thomas N, Foley E, Judd F, Gibson P, Komiti A, Couper J, and Kiropoulos L
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- 2015
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23. Comparison of the acceptability and benefits of two mindfulness-based interventions in women with breast or gynecologic cancer: a pilot study.
- Author
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Stafford L, Thomas N, Foley E, Judd F, Gibson P, Komiti A, Couper J, and Kiropoulos L
- Subjects
- Adult, Aged, Anxiety Disorders etiology, Breast Neoplasms complications, Breast Neoplasms therapy, Depressive Disorder etiology, Female, Genital Neoplasms, Female complications, Humans, Middle Aged, Pilot Projects, Quality of Life, Treatment Outcome, Anxiety Disorders therapy, Breast Neoplasms psychology, Depressive Disorder therapy, Genital Neoplasms, Female psychology, Mind-Body Therapies methods, Mindfulness methods, Patient Acceptance of Health Care psychology
- Abstract
Purpose: The aim of this study was to compare the relative benefits and acceptability of two different group-based mindfulness psychotherapy interventions among women with breast and gynecologic cancer., Methods: Data from 42 women who completed an 8-week mindfulness-based cognitive therapy (MBCT) program comprising 22 contact hours were compared to data from 24 women who completed a 6-week mindfulness meditation program (MMP) comprising 9 contact hours. Distress, quality of life (QOL), and mindfulness were evaluated pre- (T1) and post-intervention (T2). ANCOVA was used to analyse the relationship between intervention type and T1 score on outcome variable change scores. Participants' perceptions of benefit and acceptability were assessed., Results: The participants did not differ on clinical or demographic variables other than MBCT participants were more likely than MMP participants to have a past history of anxiety or depression (p = .01). Scores on distress, QOL, and mindfulness improved from T1 to T2 with medium to large effect sizes for the MMP (p=.002, d=.7; p=.001, d=.8; p=.005, d=.6, respectively) and MBCT (p<.001,d = .6; p=.008, d = .4; p<.001, d=.9, respectively) interventions. [correted]. ANCOVA showed no main effect for intervention type on outcome change scores and no interaction between intervention type and respective T1 score. Distress and mindfulness scores at T1 had a main effect on respective change scores (p = .02, ηp (2) = .87; p = .01, ηp (2) = .80, respectively). Both programs were perceived as beneficial and acceptable with no differences between the intervention types., Conclusions: Within the limits of a small, non-randomized study, these findings provide preliminary support for the utility of a brief mindfulness intervention for improving distress and QOL in a heterogeneous group of women with cancer. Abbreviated interventions are less resource intensive and may be attractive to very unwell patients.
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- 2015
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24. Mindfulness-based cognitive group therapy for women with breast and gynecologic cancer: a pilot study to determine effectiveness and feasibility.
- Author
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Stafford L, Foley E, Judd F, Gibson P, Kiropoulos L, and Couper J
- Subjects
- Adult, Affective Symptoms psychology, Aged, Feasibility Studies, Female, Humans, Meditation methods, Meditation psychology, Middle Aged, Patient Satisfaction, Pilot Projects, Program Evaluation, Quality of Life, Treatment Outcome, Affective Symptoms therapy, Breast Neoplasms psychology, Cognitive Behavioral Therapy methods, Genital Neoplasms, Female psychology, Mindfulness methods, Psychotherapy, Group methods
- Abstract
Purpose: Group-based mindfulness training is frequently described in psycho-oncology literature, but little is known of the effectiveness of mindfulness-based cognitive therapy (MBCT). We investigated the effectiveness and acceptability of MBCT for women with breast and gynecologic cancer., Methods: Fifty women were recruited to participate in eight weekly 2-h mindfulness sessions. Outcomes of distress, quality of life (QOL), post-traumatic growth, and mindfulness were assessed pre-intervention, post-intervention, and again 3 months later using validated measures. Data were analyzed with repeated measures ANOVAs with a Bonferroni correction. Participant satisfaction and evaluation were also assessed., Results: Forty-two women completed the program, and complete data were available for 36 women. Significant improvements with large effect sizes (ηρ(2)) were observed for distress (P < 0.001; ηρ(2) = 0.238), QOL (P = 0.001; ηρ(2) = 0.204), mindfulness (P < 0.001; ηρ(2) = 0.363) and post-traumatic growth (P < 0.001; ηρ(2) = 0.243). Gains were maintained 3 months post-intervention. Improvements in outcomes did not differ based on diagnostic group, psychological status, or physical well-being at entry. Change indices further support these findings. Scores on measures of distress, QOL, and post-traumatic growth decreased as a function of increased mindfulness at each time point (all P < 0.05). Participants reported experiencing the program as beneficial, particularly its group-based nature, and provided positive feedback of the therapy as a whole as well as its individual components., Conclusions: Within the limits of a non-randomized trial, these findings provide preliminary support for the potential psychosocial benefits of MBCT in a heterogeneous group of women with cancer. Future, more comprehensive trials are needed to provide systematic evidence of this therapy in oncology settings.
- Published
- 2013
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25. Knowledge of depression and depression related stigma in immigrants from former Yugoslavia.
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Copelj A and Kiropoulos L
- Subjects
- Acculturation, Aged, Depression physiopathology, Female, Humans, Male, Middle Aged, Surveys and Questionnaires, Victoria, Yugoslavia ethnology, Depression ethnology, Emigrants and Immigrants psychology, Health Knowledge, Attitudes, Practice, Stereotyping
- Abstract
The aim of the current research was to assess and compare level of depression literacy and level of depression related stigma in first generation immigrants from former Yugoslavia (FY) with a same aged Anglo Australian (AA) sample. The community sample comprised of 54 immigrants born in the FY and 54 AA born participants living in Melbourne. Participants were recruited through various social and recreational clubs. All participants completed questionnaires assessing depression literacy, self and perceived stigma and level of acculturation for the immigrants from FY in an interview format. After controlling for level of education, immigrants from the FY demonstrated lower depression literacy and higher personal and perceived depression stigma scores compared to the AA participants. The findings provide further insight to potential barriers impeding access to mental health care in immigrant populations living in Australia. Implications for mental health professionals working with immigrant populations in Australia are discussed.
- Published
- 2011
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26. A therapist-assisted cognitive behavior therapy internet intervention for posttraumatic stress disorder: pre-, post- and 3-month follow-up results from an open trial.
- Author
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Klein B, Mitchell J, Abbott J, Shandley K, Austin D, Gilson K, Kiropoulos L, Cannard G, and Redman T
- Subjects
- Adult, Aged, Analysis of Variance, Female, Humans, Life Change Events, Male, Middle Aged, Patient Satisfaction, Patient Selection, Professional-Patient Relations, Psychiatric Status Rating Scales, Severity of Illness Index, Stress Disorders, Post-Traumatic diagnosis, Surveys and Questionnaires, Treatment Outcome, Cognitive Behavioral Therapy methods, Internet, Remote Consultation methods, Stress Disorders, Post-Traumatic therapy
- Abstract
This study was an open trial evaluation of a 10-week therapist-assisted cognitive behavior therapy (CBT) internet intervention (PTSD Online) undertaken with people with a primary clinical diagnosis of posttraumatic stress disorder (PTSD) (n=22) at pre-assessment. Participants were re-assessed at post-assessment and 3-month follow-up. Significant improvements on PTSD severity ratings and related PTSD symptomatology were observed at post-assessment and maintained at 3-month follow-up. At post-assessment, 69.2% of the sample showed clinically significant improvement and 77% of the sample at follow-up assessment. Non-significant, yet improved, change was observed on all other general psychological measures. Overall, treatment satisfaction was good (69%), participant therapeutic alliance ratings were high (87.5%), and the average total therapist time required was 194.5 min. PTSD Online appears to be an efficacious treatment option for people with PTSD that can be provided entirely remotely, with far less therapist time than traditional face-to-face treatment, and without compromising therapeutic alliance., ((c) 2010 Elsevier Ltd. All rights reserved.)
- Published
- 2010
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27. Internet-based treatment for panic disorder: does frequency of therapist contact make a difference?
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Klein B, Austin D, Pier C, Kiropoulos L, Shandley K, Mitchell J, Gilson K, and Ciechomski L
- Subjects
- Adolescent, Adult, Aged, Female, Humans, Male, Middle Aged, Panic Disorder psychology, Prevalence, Young Adult, Internet instrumentation, Internet statistics & numerical data, Panic Disorder epidemiology, Panic Disorder therapy, Professional-Patient Relations, Psychotherapy instrumentation, Psychotherapy statistics & numerical data
- Abstract
Internet-based interventions with therapist support have proven effective for treating a range of mental health conditions. This study examined whether frequency of therapist contact affected treatment outcomes. Fifty-seven people with panic disorder (including 32 with agoraphobia) were randomly allocated to an 8-week Internet-based cognitive behavioural treatment intervention (Panic Online) with either frequent (three e-mails per week) or infrequent (one e-mail per week) support from a psychologist. Posttreatment, intention-to-treat analyses revealed that both treatments were effective at improving panic disorder and agoraphobia severity ratings, panic-related cognitions, negative affect, and psychological and physical quality of life domains, with no differences between conditions. High end-state functioning was achieved by 28.6% of the frequent and infrequent participants, respectively. Therapist alliance, treatment credibility, and satisfaction also did not differ between groups, despite significantly greater therapist time invested in the frequent contact condition. The results provide evidence that the effectiveness of Internet-based mental health interventions may be independent of the frequency of therapist support and may, therefore, be more cost-effective than previously reported.
- Published
- 2009
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28. A therapist-assisted Internet-based CBT intervention for posttraumatic stress disorder: preliminary results.
- Author
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Klein B, Mitchell J, Gilson K, Shandley K, Austin D, Kiropoulos L, Abbott J, and Cannard G
- Subjects
- Adult, Female, Humans, Male, Middle Aged, Stress Disorders, Post-Traumatic psychology, Cognitive Behavioral Therapy instrumentation, Cognitive Behavioral Therapy methods, Internet instrumentation, Professional-Patient Relations, Stress Disorders, Post-Traumatic therapy
- Abstract
Posttraumatic stress disorder (PTSD) is a debilitating mental health condition frequently associated with psychiatric comorbidity and diminished quality of life, and it typically follows a chronic, often lifelong, course. Previous research has shown that trauma-related psychopathology (but not necessarily clinical PTSD) can be effectively treated via the Internet. This study is the first of its kind to report on the online treatment of patients with a Diagnostic and Statistical Manual of Mental Disorders (fourth edition) clinical diagnosis of PTSD with therapist support by e-mail only. Preliminary findings are presented of an open trial involving a 10-week Internet-based therapist-assisted cognitive behavioural treatment for PTSD (PTSD Online). Pre and posttreatment measures of PTSD and related symptomatology were compared for 16 participants with a variety of trauma experiences. Participants showed clinically significant reductions in PTSD severity and symptomatology, moderate tolerance of the program content, and high therapeutic alliance ratings. No significant change was found on measures of more general psychological symptoms. The results suggest that PTSD Online appears to be an effective and accessible clinical treatment for people with a confirmed PTSD diagnosis.
- Published
- 2009
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- View/download PDF
29. An Internet-based investigation of the catastrophic misinterpretation model of panic disorder.
- Author
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Austin D and Kiropoulos L
- Subjects
- Agoraphobia diagnosis, Agoraphobia physiopathology, Agoraphobia psychology, Analysis of Variance, Cognition Disorders diagnosis, Cognition Disorders physiopathology, Defense Mechanisms, Diagnostic and Statistical Manual of Mental Disorders, Female, Humans, Life Change Events, Male, Panic Disorder diagnosis, Panic Disorder physiopathology, Perceptual Distortion physiology, Phobic Disorders diagnosis, Phobic Disorders physiopathology, Phobic Disorders psychology, Psychiatric Status Rating Scales statistics & numerical data, Psychological Theory, Stress, Psychological diagnosis, Stress, Psychological physiopathology, Stress, Psychological psychology, Surveys and Questionnaires, Arousal physiology, Cognition Disorders psychology, Internet, Models, Psychological, Panic Disorder psychology, Sensation physiology
- Abstract
The catastrophic misinterpretation (CM) model of panic disorder proposes that spontaneous panic attacks are the result of interpretation of harmless autonomic arousal as precursors to physical (e.g., heart attack) or psychological (e.g., insanity) emergency. Mixed research findings to date have provided equivocal support. The body sensations interpretation questionnaire-modified was administered via Internet to investigate core assumptions of the model among 30 people with panic disorder (PD), 28 with social anxiety disorder (SAD), and 30 non-anxious controls. The PD group gave more harm-related interpretations of ambiguous internal stimuli than both other groups, and this tendency to interpret ambiguous stimuli catastrophically was not also apparent for external/general events. Furthermore, people with PD rated harm and anxiety outcomes as more catastrophic than non-anxious controls. Results substantially support the CM model although a modification is proposed.
- Published
- 2008
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30. Exploratory economic analyses of two primary care mental health projects: implications for sustainability.
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Mihalopoulos C, Kiropoulos L, Shih ST, Gunn J, Blashki G, and Meadows G
- Subjects
- Attitude of Health Personnel, Attitude to Health, Cognitive Behavioral Therapy, Cost-Benefit Analysis, Evidence-Based Medicine, Family Practice education, Financial Support, Humans, Internet, Models, Economic, Panic Disorder therapy, Patient Acceptance of Health Care, Psychology, Quality-Adjusted Life Years, Victoria, Workforce, Mental Health Services economics, Primary Health Care economics, Program Evaluation economics
- Abstract
We evaluated an Internet-based psychological intervention supported by either general practitioners or psychologists (Panic Online), and a Primary-care Evidence-based Psychological-interventions (PEP) strategy which involves training GPs to deliver specific psychological interventions. Economic modelling suggests that Panic Online is cost-effective when supported by either GPs or psychologists. Threshold analysis of the psychological training of GPs suggests that a modest effect size for clinical benefit would be sufficient to provide an acceptable cost-effectiveness ratio. The sustainability of these approaches depends on a range of factors, including funding, workforce availability, and acceptability to consumers and health care providers.
- Published
- 2005
- Full Text
- View/download PDF
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