43 results on '"Kiper, Aytug K."'
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2. Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2
3. Popeye domain containing proteins modulate the voltage-gated cardiac sodium channel Nav1.5
4. Cloxyquin activates hTRESK by allosteric modulation of the selectivity filter
5. KCNQ1 is an essential mediator of the sex-dependent perception of moderate cold temperatures
6. Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson’s disease
7. Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2.
8. POPDC2 a novel susceptibility gene for conduction disorders
9. Ion occupancy of the selectivity filter controls opening of a cytoplasmic gate in the K2P channel TALK-2
10. A lower X-gate in TASK channels traps inhibitors within the vestibule
11. Calcium Handling Remodeling Underlies Impaired Sympathetic Stress Response in Ventricular Myocardium from Cacna1c Haploinsufficient Rats
12. TASK-1 and TASK-3 may form heterodimers in human atrial cardiomyocytes
13. Selective TASK-1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability
14. Kv1.5 blockers preferentially inhibit TASK-1 channels: TASK-1 as a target against atrial fibrillation and obstructive sleep apnea?
15. The role of acid-sensitive two-pore domain potassium channels in cardiac electrophysiology: focus on arrhythmias
16. A New Strategy for Multitarget Drug Discovery/Repositioning Through the Identification of Similar 3D Amino Acid Patterns Among Proteins Structures: The Case of Tafluprost and its Effects on Cardiac Ion Channels
17. 5-(Indol-2-yl)pyrazolo[3,4-b]pyridines as a New Family of TASK-3 Channel Blockers: A Pharmacophore-Based Regioselective Synthesis
18. Identification of a critical binding site for local anaesthetics in the side pockets of K v 1 channels
19. Gain-of-function mutation in TASK-4 channels and severe cardiac conduction disorder
20. A “Receptophore Model” for Local Anesthetics Binding Site in Cardiac Ion Channels
21. Identification of a critical binding site for local anaesthetics in the side pockets of Kv 1 channels.
22. Discovery of Novel TASK-3 Channel Blockers Using a Pharmacophore-Based Virtual Screening
23. TASK Channels Pharmacology: New Challenges in Drug Design
24. Structure/Activity Analysis of TASK-3 Channel Antagonists Based on a 5,6,7,8 tetrahydropyrido[4,3-d]pyrimidine
25. The molecular basis for an allosteric inhibition of K+-flux gating in K2P channels
26. A pharmacological master key mechanism that unlocks the selectivity filter gate in K + channels
27. A Pharmacological Masterkey Mechanism to Unlock the Selectivity Filter Gate in K+ Channels
28. Author response: The molecular basis for an allosteric inhibition of K+-flux gating in K2P channels
29. Molecular Pharmacology of K2P Potassium Channels.
30. The VAMP‐associated protein VAPB is required for cardiac and neuronal pacemaker channel function
31. Stretch-activated potassium currents in the heart: Focus on TREK-1 and arrhythmias
32. Sodium permeable and “hypersensitive” TREK ‐1 channels cause ventricular tachycardia
33. Stress-Kinase Regulation of TASK-1 and TASK-3
34. Identification of the A293 (AVE1231) Binding Site in the Cardiac Two-Pore-Domain Potassium Channel TASK-1: a Common Low Affinity Antiarrhythmic Drug Binding Site.
35. A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels.
36. Functional mutagenesis screens reveal the ‘cap structure’ formation in disulfide-bridge free TASK channels
37. An N-terminal deletion variant of HCN1 in the epileptic WAG/Rij strain modulates HCN current densities
38. Kv1.5 blockers preferentially inhibit TASK-1 channels: TASK-1 as a target against atrial fibrillation and obstructive sleep apnea?
39. The role of acid-sensitive two-pore domain potassium channels in cardiac electrophysiology: focus on arrhythmias
40. Activation of the alkaline-activated K2PK+channel talk-2 requires opening of two functionally coupled gates
41. 5-(Indol-2-yl)pyrazolo[3,4- b ]pyridines as a New Family of TASK-3 Channel Blockers: A Pharmacophore-Based Regioselective Synthesis.
42. Molecular Pharmacology of K 2P Potassium Channels.
43. The molecular basis for an allosteric inhibition of K + -flux gating in K 2P channels.
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