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Background: High-flow nasal cannula (HFNC) is an option for respiratory support in patients with acute hypoxic respiratory failure. To improve patient outcomes, reduce ICU-associated costs, and ease ICU bed availability, a multi-phased, comprehensive strategy was implemented to make HFNC available outside the ICU under the supervision of pulmonology or trauma providers in cooperation with a dedicated respiratory therapy team. The purpose of this study was to describe the education and implementation process for initiating HFNC therapy outside the ICU and to convey key patient demographics and outcomes from the implementation period., Methods: HFNC therapy was implemented at a tertiary hospital in the Midwest, with systematic roll-out to all in-patient floors over a 9-month period. Utilization of the therapy and patient outcomes were tracked to ensure safety and efficacy of the effort., Results: During the implementation period, 346 unique subjects met study inclusion criteria. Median (interquartile range) hospital length of stay was 8 d (4-12), and median duration of HFNC therapy was 44 h (18-90). Two thirds of subjects ( n = 238) received the entire course of HFNC therapy outside the ICU, and more than half of subjects ( n = 184) avoided the ICU for their entire hospitalization. Moreover, 6% of subjects in the study group escalated from HFNC to noninvasive ventilation, and 5% of subjects escalated from HFNC to mechanical ventilation., Conclusions: A comprehensive implementation process and a robust therapy protocol were integral to initiating and managing HFNC in all hospital locations. Study findings indicate that patients with acute hypoxic respiratory failure can safely receive HFNC therapy outside the ICU with appropriate patient selection and staff education., Competing Interests: Fisher & Paykel Healthcare provided grant support and donated disposables to UnityPoint Health to support nurse and physician education during the implementation phase of the study. Ms Jackson and Dr Trump have disclosed relationships with Fisher & Paykel HealthCare. The other authors have disclosed no conflicts of interest., (Copyright © 2021 by Daedalus Enterprises.)

Purpose: The purpose of this study is to determine if patient mobility achievements in an intensive care unit (ICU) setting are sustained during subsequent phases of hospitalization, specifically after transferring to inpatient floors and on the day of hospital discharge., Materials and Methods: The study is an analysis of adult patients who stayed in the ICU for 48 hours or more during the second quarter of 2013. The study sample included 182 patients who transferred to a general inpatient floor after the ICU stay., Results: Patients experienced an average delay of 16 hours to regain or exceed chair level of mobility and 7 hours to regain ambulation level after transferring to an inpatient floor. One third of patients ambulated in the ICU, and those patients had significantly shorter post-ICU and hospital stays compared with patients who did not ambulate in the ICU. Delays in regaining mobility on the floor were modestly associated with initial Morse Fall Score and being male., Conclusions: Mobility progression through the hospital course is imperative to improving patient outcomes. Study findings show the need for improvement in maintaining early ICU mobilization achievement during the crucial phase between ICU stay and hospital discharge., (Copyright © 2015 Elsevier Inc. All rights reserved.)