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9. Possible Use of Non-purine Selective Xanthine Oxidoreductase Inhibitors for Prevention of Exercise-induced Acute Kidney Injury Associated with Renal Hypouricemia

Author

Aizawa, Chiharu, primary, Okabe, Masahiro, additional, Takahashi, Daisuke, additional, Sagasaki, Makoto, additional, Watanabe, Mao, additional, Fujimoto, Toshinari, additional, Yoshioka, Yuuki, additional, Katsuma, Ai, additional, Kimura, Ai, additional, Miyamoto, Daisuke, additional, Sato, Nana, additional, Okamoto, Ken, additional, Ichida, Kimiyoshi, additional, Miyazaki, Yoichi, additional, and Yokoo, Takashi, additional

Published
2023
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13. Online Practice in Time of COVID-19 Crisis

Author

Tsuda, Rieko, Izumi, Taeko, Kimura, Ai, and Inagaki, Yukari

Subjects
感情の変化, 介護福祉実習, リアリティ, オンライン, 360度カメラ
Abstract

COVID‐19の感染拡大により、オンライン実習においてリアリティを追及した実習が行えるように、実習先施設の映像を360度カメラで撮影し、その映像をVRゴーグルにより視聴する実習を取り入れ、その効果と課題を明らかにすることを目的に、介護福祉養成課程3回生18名にアンケート調査を実施した。その結果、360度カメラによる映像の視聴は実習最終日よりも実習19日目の情報収集の段階で学びが大きい(p < .009)ことが明らかになり、細かい点までの観察が繰り返しでき、介護者・利用者双方からの仮想体験が可能で、学生の気づきに効果があった。一方で、映像酔いや目への負担など、身体的負担につながることも示された。さらに、感情面では実習前から実習後にマイナス感情からプラス感情へと改善（ｐ < .001）が確認できた。今後も、ポストコロナや大災害により突然平穏な日常が奪われる可能性があることを視野に入れ、実習先施設と連携を強化する中でオンラインを活用した実習体験プログラムを構築することが重要である。

Published
2022

16. Different Clinical Courses of Nephronophthisis in Dizygotic Twins

Author

Oki, Yutaro, primary, Katsuma, Ai, additional, Okabe, Masahiro, additional, Watanabe, Mao, additional, Sagasaki, Makoto, additional, Takahashi, Daisuke, additional, Kimura, Ai, additional, Kato, Junichiro, additional, Ueda, Hiroyuki, additional, Hataya, Hiroshi, additional, Fujimaru, Takuya, additional, Mori, Takayasu, additional, Sohara, Eisei, additional, Uchida, Shinichi, additional, Miyazaki, Yoichi, additional, and Yokoo, Takashi, additional

Published
2023
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26. About the school for the deaf in Bali, lndonesia. SLB A NEGERI DENPASAR

Author

Desak Made Wihandani and Kimura, Ai

Subjects
聴覚障がいのある子どもの施設, SLB A NEGERI DENPASAR, バリ州
Abstract

本稿は、バリ州における聴覚障がいのある子どもの施設であるスシュルサ・プレイグループ教育機関の概要をまとめたものである。 スシュルサ・プレイグループは、聴覚障がいを抱え、周囲とのコミュニケーションや意思の疎通に課題がある子どもに教育サービスを提供している施設である。理念や方針、アプローチの方法、設備等を報告する。

Published
2019

31. The Effectiveness of Training Programs on the Fidelity of Neuropsychological Tests

Author

Takeda, Shinya, Banno, Yuka, Sugimoto, Taiki, Fujii, Fumi, Kimura, Ai, Sakurai, Takashi, Takeda, Shinya, Banno, Yuka, Sugimoto, Taiki, Fujii, Fumi, Kimura, Ai, and Sakurai, Takashi

Abstract

Background: There will probably be an exponential increase in the number of seniors suffering from dementia, as aging is the greatest risk factor for this disease. Therefore, neuropsychological tests to assessing dementia are likely to play an increasingly important role for medical services in Japan. This study developed and evaluated the usefulness of a training program on neuropsychological tests aimed at promoting the understanding of testers with regard to the cognitive functions and communication required in the neuropsychological testing process. Methods: The subjects of this study comprised 20 individuals engaged in administrating neuropsychological tests at the Japan-Multidomain Intervention Trial for Prevention of Dementia in Older Adults with Diabetes. A four-hour training session was held. The first part of the training program focused on “cognitive functions and communication;” the second addressed “neuropsychological tests.” As the main evaluation criteria, a fidelity checklist was created with 14 items designed to measure success or failure with regard to important and easily mistakable aspects of implementing each neuropsychological test. They were conducted three times: before, immediately after, and six months after the training. Results: The main effect of time was significant for the “fidelity” score. The effect size was large at η2 = 0.69. A simple main effect test using the Bonferroni method revealed significant differences between the pre-training and post-training values and between the pre-training and six-month point values. However, no significant differences were found in self-efficacy scores before, immediately after, and six months after the training. Conclusion: This outcome indicates that the fidelity of the subjects to neuropsychological tests increased as a result of the training program, and that this improvement was maintained through the six-month period following the program. Moreover, the large effect size suggests that the tra

Published
2019

32. AMP‐activated protein kinase in the amygdala and hippocampus contributes to enhanced fear memory in diabetic mice.

Author

Yamagishi, Aimi, Yonemochi, Naomi, Kimura, Ai, Takenoya, Fumiko, Shioda, Seiji, Waddington, John L., and Ikeda, Hiroko

Subjects
*AMP-activated protein kinases, *PROTEIN kinases, *AMPA receptors, *WESTERN immunoblotting, *MENTAL illness, *AMYGDALOID body
Abstract

Background and Purpose Experimental Approach Key Results Conclusions and Interpretation Diabetic patients have an increased risk of psychiatric disorders. Because hyperglycaemia increases L‐lactate in the brain and L‐lactate inhibits AMP‐activated protein kinase (AMPK), this study investigated the role of L‐lactate and AMPK in strengthened fear memory, a model for human psychiatric disorders, in diabetic mice.The diabetic model was mice injected with streptozotocin. Fear memory was measured using the conditioned fear test with low (0.45 mA) or high (0.50 mA) foot shock to cause low and high freezing, respectively. Protein levels of AMPK and phosphorylated AMPK (pAMPK) were measured by western blotting and immunohistochemistry.At 0.45 mA, the AMPK inhibitor dorsomorphin increased freezing, which was inhibited by the AMPK activator acadesine. In contrast, at 0.50 mA, acadesine decreased freezing, which was inhibited by dorsomorphin. In diabetic mice, pAMPK was decreased in the amygdala and hippocampus. Diabetic mice showed increased freezing at 0.45 mA, which was inhibited by acadesine. In the amygdala and hippocampus, L‐lactate was increased in diabetic mice and injection of L‐lactate into non‐diabetic mice increased freezing at 0.45 mA. In addition, L‐lactate decreased pAMPK in the hippocampus, but not the amygdala, and increase in freezing induced by L‐lactate was inhibited by acadesine. Dorsomorphin‐induced increase in freezing was inhibited by the AMPA receptor antagonist NBQX.In diabetic mice, L‐lactate is increased in the amygdala and hippocampus, possibly through hyperglycaemia, which strengthens fear memory through inhibition of AMPK and activation of glutamatergic function. [ABSTRACT FROM AUTHOR]

Published
2024
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33. Estimation of salt intake from spot urine samples in patients with chronic kidney disease

Author

Ogura Makoto, Kimura Ai, Takane Koki, Nakao Masatsugu, Hamaguchi Akihiko, Terawaki Hiroyuki, and Hosoya Tatsuo

Subjects
Chronic kidney disease, Salt intake, Urinary sodium excretion, Diseases of the genitourinary system. Urology, RC870-923
Abstract

Abstract Background High salt intake in patients with chronic kidney disease (CKD) may cause high blood pressure and increased albuminuria. Although, the estimation of salt intake is essential, there are no easy methods to estimate real salt intake. Methods Salt intake was assessed by determining urinary sodium excretion from the collected urine samples. Estimation of salt intake by spot urine was calculated by Tanaka’s formula. The correlation between estimated and measured sodium excretion was evaluated by Pearson´s correlation coefficients. Performance of equation was estimated by median bias, interquartile range (IQR), proportion of estimates within 30% deviation of measured sodium excretion (P30) and root mean square error (RMSE).The sensitivity and specificity of estimated against measured sodium excretion were separately assessed by receiver-operating characteristic (ROC) curves. Results A total of 334 urine samples from 96 patients were examined. Mean age was 58 ± 16 years, and estimated glomerular filtration rate (eGFR) was 53 ± 27 mL/min. Among these patients, 35 had CKD stage 1 or 2, 39 had stage 3, and 22 had stage 4 or 5. Estimated sodium excretion significantly correlated with measured sodium excretion (R = 0.52, P 170 mEq/day (AUC 0.835). Conclusions The present study demonstrated that spot urine can be used to estimate sodium excretion, especially in patients with low eGFR.

Published
2012
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37. Impact of hip fracture on all‐cause mortality in Japanese patients with type 2 diabetes mellitus: The Fukuoka Diabetes Registry

Author

Komorita, Yuji, primary, Iwase, Masanori, additional, Idewaki, Yasuhiro, additional, Fujii, Hiroki, additional, Ohkuma, Toshiaki, additional, Ide, Hitoshi, additional, Jodai‐Kitamura, Tamaki, additional, Yoshinari, Masahito, additional, Murao‐Kimura, Ai, additional, Oku, Yutaro, additional, Nakamura, Udai, additional, and Kitazono, Takanari, additional

Published
2019
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42. The result of Denmark social welfare study 一Change of Daily Life Skill for College Students一

Author

Kimura, Ai

Subjects
日常生活スキル尺度（大学生版）, デンマーク, 研修
Abstract

本論文は，デンマーク社会福祉研修に有志で参加した学生を研究協力者とし，研修の直前オリエンテーション時と帰国時に心理測定尺度「日常生活スキル尺度（大学生版）」を実施した。学生の「効果的に日常生活を過ごすために必要な学習された行動や内面的な心の動き」に変化があるか研修前後の比較をすることで，研修の成果を測ることを目的とした。その結果，日常生活スキル尺度（大学生版）全体の合計点および「リーダーシップ」「計画性」「感受性」「情報要約力」「自尊心」の5項目，対人スキル，個人的スキルにおいて有意差を確認できた。

Published
2015

43. Report of Volunteer Activities after the Grand Eastern Japan Earthquake

Author

Kimura, Ai

Subjects
ボランティア, 陸前高田, 東日本, 復興支援
Abstract

東日本大震災から月日は流れた．しかし，今も人々の生活再建のために復興が続いている．経済的にも人材も不足している現状にある．そのような中で，筆者は岩手県陸前高田市を中心にボランティア活動に参加した．その時，自身が見聞きしたことを伝えるため，また，東日本におけるボランティアのあり方を再考するために，ここに報告する．

Published
2014

44. Impact of hip fracture on all‐cause mortality in Japanese patients with type 2 diabetes mellitus: The Fukuoka Diabetes Registry.

Author

Komorita, Yuji, Iwase, Masanori, Idewaki, Yasuhiro, Fujii, Hiroki, Ohkuma, Toshiaki, Ide, Hitoshi, Jodai‐Kitamura, Tamaki, Yoshinari, Masahito, Murao‐Kimura, Ai, Oku, Yutaro, Nakamura, Udai, and Kitazono, Takanari

Subjects
TYPE 2 diabetes, HIP fractures, DIABETES, CHRONIC kidney failure, LOGISTIC regression analysis, CARDIOVASCULAR diseases
Abstract

Aims/Introduction: Patients with type 2 diabetes mellitus have an increased hip fracture risk. We investigated the relationship between hip fracture and all‐cause death in patients with type 2 diabetes in comparison with cardiovascular disease (CVD) or end‐stage renal disease (ERSD). Materials and Methods: In total, 4,923 Japanese participants with type 2 diabetes (mean age 65 years, 2,790 men, 2,133 women) were followed for a median of 5.3 years (follow‐up rate 99.5%). We evaluated the associations between the presence of hip fracture (n = 110), upper limb fracture (n = 801), CVD (n = 1,344), ESRD (n = 104) and all‐cause death by logistic regression analysis. Results: A total of 309 participants died during follow up. Multivariate‐adjusted odds ratios (ORs) for all‐cause mortality were significantly higher in participants with hip fractures than those without hip fractures (OR 2.67, 95% confidence interval [CI] 1.54–4.41), whereas the ORs for upper limb fracture were not significant. The ORs for all‐cause mortality were significantly higher in participants with CVD than those without CVD (OR 1.78, 95% CI, 1.39–2.70) and ESRD (OR 2.36, 95% CI 1.32–4.05). The ORs for all‐cause mortality of hip fracture were not affected by further adjustment for CVD and ESRD (OR 2.74, 95% CI 1.58–4.54). The cause of death was infection (40.0%), malignant neoplasm (25.0%) and CVD (15.0%) among participants with hip fracture. Conclusions: Hip fractures were associated with an increased risk of death among Japanese patients with type 2 diabetes, independently of CVD and ESRD. [ABSTRACT FROM AUTHOR]

Published
2020
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45. 不登校半減計画プロジェクトに対する学校関係者の評価に関する研究 : 不登校問題の改善効果とプロジェクトに対する評価を中心に

Author

KOBAYASHI, Masayuki, HIRANO, Chikako, ITO, Toru, KIMURA, Ai, EJIRI, Kana, KIM, YoungMin, HAYAKAWA, Keiko, MURAMATSU, Ayako, KOBAYASHI, Masayuki(Tokyo Gakugei University), HIRANO, Chikako(Tokyo Gakugei University Graduate School of Education), ITO, Toru(Alternative Classroom for non-attendance pupils, Koganei City), KIMURA, Ai(Mental Clinic Andou, Fuchu city), EJIRI, Kana(Tokyo Gakugei University Graduate School of Education), KIM, YoungMin(Tokyo Gakugei University Graduate School of Education), HAYAKAWA, Keiko(Tokyo Gakugei University Graduate School of Education), and MURAMATSU, Ayako(Tokyo Gakugei University Graduate School of Education)

Published
2006

50. 大学生のストレス過程に関する検討 : 認知的評価と個人内要因に注目して

Author

Kimura, Ai, Kobayashi, Masayuki, Mastuda, Osamu, Kimura, Ai(Integrated Research Center for Educational Practice, Tokyo Gakugei University), Kobayashi, Masayuki(Integrated Research Center for Educational Practice, Tokyo Gakugei University), and Mastuda, Osamu(Department of Psychology, Tokyo Gakugei University)

Subjects
Stressor, Cognitive Appraisal, Stress Responses, Irrational Belief, Neurotic Tendency
Published
2003

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