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11. Detection of Corynebacterium bovis infection in athymic nude mice from a research animal facility in Korea.

Author

Kim TH, Kim DS, Han JH, Chang SN, Kim KS, Seok SH, Kim DJ, Park JH, and Park JH

Subjects
Animals, Corynebacterium Infections pathology, Mice, Nude, Polymerase Chain Reaction veterinary, RNA, Ribosomal, 16S genetics, Republic of Korea, Rodent Diseases pathology, Skin Diseases, Bacterial pathology, Corynebacterium isolation & purification, Corynebacterium Infections microbiology, Mice, Rodent Diseases microbiology, Skin Diseases, Bacterial microbiology
Abstract

Corynebacterium (C.) bovis infection in nude mice causes hyperkeratosis and weight loss and has been reported worldwide but not in Korea. In 2011, nude mice from an animal facility in Korea were found to have white flakes on their dorsal skin. Histopathological testing revealed that the mice had hyperkeratosis and Gram-positive bacteria were found in the skin. We identified isolated bacteria from the skin lesions as C. bovis using PCR and 16S rRNA sequencing. To the best of our knowledge, this is the first report of C. bovis infection in nude mice from Korea.

Published
2014
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