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This study explores the structural relationship among digital literacy, learning strategies, and core competencies among South Korean college students as well as the group differences between these variables depending on individual characteristics. Data analysis was conducted by correlation analysis, independent sample "t"-testing, and structural equation modelling. Participants were 916 college students from 10 colleges in South Korea. The results showed that (i) no difference between groups existed in digital literacy and core competencies; however, a group difference existed in learning strategy; (ii) digital literacy had a direct effect on core competencies and learning strategies had an indirect effect on the influence of digital literacy on core competencies; and (iii) digital literacy can enhance the effect of core competencies when mediating learning strategy. This study suggests areas for future research, including developing digital technology-enhanced, competency-driven learning resources that account for the effects of cognitive, meta-cognitive, and resource management; the relationship between digital literacy and core competencies of learner characteristics such as achievement goal orientation, learning style, and academic self-efficacy; the effect of individual digital technologies on core competencies based on individual learning strategies through experimental and quasi-experimental designs; and qualitative studies on employing digital technologies and learning strategies.

Activation of regulatory elements is thought to be inversely correlated with DNA methylation levels. However, it is difficult to determine whether DNA methylation is compatible with chromatin accessibility or transcription factor (TF) binding if assays are performed separately. We developed a fast, low-input, low sequencing depth method, EpiMethylTag, that combines ATAC-seq or ChIP-seq (M-ATAC or M-ChIP) with bisulfite conversion, to simultaneously examine accessibility/TF binding and methylation on the same DNA. Here we demonstrate that EpiMethylTag can be used to study the functional interplay between chromatin accessibility and TF binding (CTCF and KLF4) at methylated sites.

Large-scale inter-combustor thermoacoustic interactions occur frequently in modern can-annular gas turbine combustion systems due to the presence of an annular cross-talk section upstream of the first stage turbine stator vanes. Although the whole system's modal dynamics depend on the relative dominance of low-frequency planar or high-frequency transverse acoustic waves, the majority of prior studies have chiefly focused on longitudinal mode instabilities. Motivated by the paucity of detailed information, here we examine high-frequency transverse acoustic interactions between two adjacent lean-premixed hydrogen combustors connected via two different pathways, known as cross-fire (XF) and cross-talk (XT) sections. We observe that the dual-combustor system undergoes high-frequency spinning mode in the clockwise direction, manifested as well-defined limit cycles with peak-to-peak amplitude of around 10 kPa. The transverse pressure oscillations, in contrast to the well-established low-frequency mutual synchronization dynamics, are not fully synchronized even in the presence of cross-talk communication. This situation leads to the formation of two closely-spaced 1T modes at 4.76 and 4.86 kHz in the respective hydrogen combustors, accompanied by the beating of the pressure fluctuations solely in the XF tube section. Remarkably, the pressure waves induced near the XF tube section tend to lag behind the pressure waves spinning in the injector face, demonstrating the existence of the angular shift characteristically connected to the high-frequency transverse combustion dynamics. • High-frequency transverse instabilities are investigated in subscale dual-combustor test environments. • Distinctive features derived from high-frequency cross-talk interactions are experimentally identified. • Collective dynamics are characterized by weak coupling-induced beating in cross-fire section. • Angular shift in spinning modes is generated from two acoustically coupled hydrogen combustors. [ABSTRACT FROM AUTHOR]